LOCUS       c00035_gnlPro..        13695 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BDEKBOIK_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:22:18
            Original ID  :: gnl|Prokka|BDEKBOIK_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13695
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..192
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="LGFVRHCQVRSPGLLRTFQCNIYFLRCATMRKQLSGILFLVQGNL
                     VMKKLPTADAAGSFYRAS"
     protocluster    1..13695
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[205:3695]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      206..3695
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13695
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13695
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(206..1036)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.2e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1014..2972)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.7e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2994..3695)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3917..4168
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="VLDADFAAARAGVLDVAAFLDRVDRGEGGADFRYHALMDVLPLLS
                     ASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4201..4986
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5020..5253)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5683..6390)
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6421..6510)
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             6715..7425
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             complement(8102..8980)
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MIAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWE
                     LYTAFMENGRPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMS
                     HHAASKFCEWLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSN
                     DRYQKTGSKKPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPTKDPLVIIPGAPHIVR
                     GGSWEDDPDSLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTM
                     HRLWNFSKGEP"
     CDS             complement(9331..10104)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_12"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10101..10259)
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MKTVRPPMHSGKMKRPDSSPPPRFSPLFFIPGTPFPRMGSCAAKS
                     ISSLPEP"
     CDS             complement(10204..10542)
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="LAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDAL
                     IEKMEKRMEMLDNRCRQEGKRLFEARYYGSAASKDILENSDEFSDLVEPDENGAPPDAL
                     RENEEAGQ"
     CDS             complement(10786..12309)
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="VALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIVGYLPQEAS
                     EPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANGYQLEPKAK
                     KILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLDLLSLLWLQ
                     RYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDVRFEQLQAA
                     YRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVFKFNFPQPP
                     RSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKILAGIIPID
                     SGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGSFLFRRLDV
                     EKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKHYEGTLVFI
                     SHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12636..13226
                     /locus_tag="ctg35_16"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWDEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 ttaggtttcg tccggcattg ccaagtacgg tctcctggat tactgagaac cttccagtgt
       61 aacatttatt ttttacgctg cgcgacgatg aggaagcaac tgtctggtat tttattcctg
      121 gttcaaggaa acctggtaat gaaaaaactc ccgacagccg atgccgccgg gagtttttac
      181 agagcgtctt aagaaggaat cttctttaga aacagaggcc ttccttggcg ttggcccgca
      241 tgaagtcgcg gttgaggcgg gcgatgttgt ccacgctgat gcctttcggg caggcggctt
      301 cacattcata ctggttcgtg cagttgccaa agccttccgc ttccatctgc ttcatcatgg
      361 ccaggacgcg cttggaacgt tccggctggc cctgcggcag cagattgaga tgggcgatct
      421 tggcggaggt gaacagcatg gcggaggcgt ttttacagga ggccacgcag gcgccgcagc
      481 cgatgcaggc ggccgcgtca aaggcggcgt ccgctttcac tttttccacg gcgatgttgt
      541 tggcgttcgg cgcggaaccg gtacgcacgt caatatagcc tccagcggcg atgatgcggt
      601 ccagggcgga gcggtccacc atcaggtccc gcaggattgg gaaagccttc gcgcggaagg
      661 gttcaatcca gacggtatcg ccgtccttga acttgcgcat gtgaagctgg caagtggtca
      721 cctggcgttc cggcccgtgg ggaatgccgt tgatggttag ggagcacatg ccgcagatgc
      781 cttcccggca gtcgtggtca aaatggatgg gttccttgcc ttccttgacc aggccttcat
      841 tgacgatgtc cagcatttcc aggaaggagg cgtccaccgg aatgtccttg gcggcatagg
      901 tctcaatgcg gcccttggct tcccggtttt cctggcgcca gaccttgaga gtgagattga
      961 gtgttttagc catgttataa tctttctttt gagtgttaat gtattggcta tctttacttg
     1021 tagctgcgga tggcaaggtg cacgttctcg aaggtcagcg gttccttgtg gagaacaggc
     1081 aggctgtcca cgccagtgta ttcccaggcg gctacatagg cgtattcatc gtcgttgcgc
     1141 ttagcttcgc cgtccggcag ctggtattcc acgcggaagt gggcgccgca ggattcctgg
     1201 cggttcaggg cgtcatagca gagcagctgg gcgaattcca ggaagtcggc cacgcggcag
     1261 gctttttcca gttccgcgtt gatgccgtcc gccgtgccgg ttacgcgcac gttttcccag
     1321 aattccttgc ggagctgggg aatgcgttca atggcgtggg tcaggctttc ttccgtgcgg
     1381 gccatgccgc agtcttccca cataatgagg cccagttccc ggtggaagga gtccaccgtc
     1441 ttggtgccct tcacattcag gagcttgttg atgcgttcct tcacttcgtc ttccgcagcc
     1501 ttgaattccg gggcggcggt ggtgacggcg ccgggtttgg tggtcgtcag gtaagcgggc
     1561 agcgtggcgg gaatgacgaa gtagccgtca gacaggccct gcatcagggc ggaggctccc
     1621 aggcggttgg cgccgtggtc ggagaagttg gcttcaccga ggacgtgcag ccccttcaca
     1681 ttggacatga ggttgtagtc cacccacagg ccgcccatgg tgtagtggga ggcggggtag
     1741 atcatcatgg gcgtttcatg ggggtcgtcg tccgtgattt cttcgtacat gtcaaacaga
     1801 ttgccgtatt ggccgtcaat ccattcgcgg cccatgcgct tgatttcatc cgcaaaatcc
     1861 aggaagacgc ccttgccggt gacggccacg ccgcggccgt cgtcgcaggc ttccttggcg
     1921 gcgcgggagg aaatgtcgcg cggggccagg ttgccgaagg agggatactt gcgttccagg
     1981 tagtagtccc gttcttcttc gggaacatcg gaaggcttga tttccttttt acggattttt
     2041 tctgcggttt cacgggactt gggcacccag atgcggccgc tgttgcggag ggattccgac
     2101 atcagcgtca gtttggactg gtagtcgccc ttgaccggaa tgcaggtggg gtggatttgt
     2161 gtgaagcagg ggttggcgaa gaaggcaccg cgcttgtagg ccttgtaggc ggcagtgacg
     2221 ttgcagccca tcgcgttggt ggacaggaag aacacgttgc cgtagccgcc cgtgcagagc
     2281 aggacggtat cccctgcgta ggatttgatt tcgccggtaa ccagattgcg ggtgacgatg
     2341 cccttggctt cgccgtccac caacaccaga tccatcattt catggcggga gaacatttca
     2401 atgtgtccct tggccacttc cttttccagg gcctggtagg cacccagcag tagctgctgg
     2461 cccgtctgtc cgcgtgcgta gaaggttcgc ttgagctggg cgccaccgaa ggagcggttg
     2521 tccagcaggc cgccgtattc acggccgaag ggaacgccct gggccacaca ctggtcaatg
     2581 atgttggagg agacttccgc cagacggtag acattggctt cacgggcgcg gaagtcgccg
     2641 cctttaacgg tgtcgtaaaa caggcggtaa acggagtcgc cgtcgttctg gtagttcttg
     2701 gccgcgttaa tgccgccctg ggccgcaatg gagtgggcgc ggcgggggct gtcctggtag
     2761 cagaagcatt tgacgttgta gccaagttcg gcaagcgtgg cggcagcgga ggcgccagcc
     2821 aggccggaac ctaccacaag taccgtgtac ttgcgcttgt tgttcggatt gatcagtttg
     2881 gactcaagtt tgtacttgga ccatttgtcc tgaatagggc cggagggaat tttggcatcc
     2941 ggcatccagt cgcttacggg aaaattaatc atgactttga gaggagttga tggttatttg
     3001 atgataccca gaagaaccga gaccggcacg gagatgaagc ccaggcagat aatcgcgccg
     3061 taggcgatgg cgataaagtt gtagaagggc cggattttgc gggaatcgac gcccacagtc
     3121 tggaagatgg actgtacccc gtggcgcaga tggctgaaca gcatcagaac ggccaggatg
     3181 tagaaggcgg agcaccatac gttggagaat ccggtcacga tcatcttgta cacgtcaaag
     3241 gtttccaccg taccgtcgga aatgaaggtg gtgaactggg cggggtcgta tcccacgcgc
     3301 agggtgtact ggtacaggtg gtagatcagg aacaccagga cggtcagacc ggtatagatc
     3361 atgtagcggg aggagagcgt tgccttgatg gtgttcttga acacgtaggg ttcgcgggcc
     3421 gcatggtttt ccagcttcag ctggatggtc agccagacgt ggatgatgaa gatcaccgca
     3481 agccccgcgc ggattcccca gagggctgct tccggcatgg agtgcaggcc gtgggcgtag
     3541 gtgttgatcc attcagggcc tccgaagatg agaaggttgc ctgccaggtg tcccgcaagg
     3601 aacaagacca aacataaccc cgtcagagcc acaatgattt tgcggccgat ggaggatgtc
     3661 acgaatgtac atatggtttt tactagtgca ttcataggcg ctctaatgaa ataaatgcgt
     3721 cttcacagga tgcccggttc aagcccggat ggcaagcctc ttcttgaatt tccggcgctt
     3781 ttcggatttt tgaaaagccg gggaaagagg ttgctgttta tcagtttgga atggttatca
     3841 ttttgttgcc tgttccggct tgacgaggct ttccgcatag gcgtatcgtc tgtgcatgaa
     3901 aagaagtaaa aaggaggtgc tggacgcgga tttcgcagcg gcgcgcgccg gcgttctgga
     3961 tgtggccgca tttctggacc gggtggaccg cggggaaggg ggggcggatt tccgctacca
     4021 tgccctgatg gatgttcttc ccctcttgtc cgcatccggc cccggacgcg tccgggccat
     4081 tctggaagcc ctttcctaca gggatgacac cgtgccggaa accgccgcag ccaaagcggc
     4141 ctgcggagcc ccgaacctca gcaaataaga atgatggctt tcatagaacc tcatatacat
     4201 atggtgtgcc gcaccacgga cgaataccgg gccatggcgc aggccggctg cctggcggta
     4261 ggggaaccgg cgttctgggc cggttacgac cgttcgtccg cggacggttt ccgggattat
     4321 ttcgtacagc ttacggaatg cgaacccgcc agggcggcca agttcggcat ggaccattac
     4381 acatggctgt gcatcaatcc caaggaggcg caggacgtgg ctttcgcgcg ggatgtgatg
     4441 aaactgattc cggagttcat tgaccggccc aatgtcctcg gcatcgggga aatagggctg
     4501 aaccggaata cttcccatga aatgactatt tttgaagagc atctggatct ggcggtgcgc
     4561 ctcaaccagc ttgtgctgat tcacactccc catctggaag acaagcttaa ggggaccgta
     4621 atgattcttt ccgccctgaa aaaccgtccg gatctggacc cttgccgcgt gctggtggat
     4681 cactgtgagg aacatacctt cccgctggtg aaggaggccg gttactgggc cgggctgacc
     4741 ctttatccca ccagtaagct gaatcccaag cgggcggcgg atattctgga attgtacgga
     4801 atggaccgtg tctgggccaa ttccgcggcg gactgggggg attccgatcc cctggcgctg
     4861 acggccctgg cctgcgagct acgcaggcgc ggtttttccc ggcaggaaac ggaacgtctt
     4921 ctcctggaaa atccggagac attcatggga cagtccccga agttccggaa agtgtcgtcc
     4981 cgctaattcc gcccgaggcg cggcggaggg tacggccctc tagtccccgt ccgggaaaaa
     5041 gacggtgagg acggcgccca ggatgaccgc cgcgtcatcc agaaggccca gcctgccgat
     5101 tccgtcaaac aggaattcgt cgggagtcag gatgtaggcg ccggcggcgg ccagaaggca
     5161 tatattccgt ttgttgaaaa aacgcggttc tccttttctg cttttgaaat accggaacag
     5221 gcgcagtagc agctgctgtt tttgaaggtt catggatggg aacgggggat aaaggttcaa
     5281 gttcagccat tttcccactc cttttccctg tttcagggaa ggagtctgtt gccgacggac
     5341 ggaaaccgca gcgatccgga ccgtgcgggg aaatggattg ctgaaaggat gggctgttcc
     5401 ggatgctgag ggaagccggg ctttgcatgc tccggttccg gctgtcccgg catgggaaaa
     5461 aggggcgtgt acggaagtgg ggcggggccg gaagctcttg aaatgaccct cccgggggag
     5521 cctgaatgcc atttccccgt caagtgctgg ccgtgagggt acccagcaaa tagaagcttc
     5581 ttccccctgt tttttccggc aggtgtttga acggataagg aaaaggccgg ctcacgattt
     5641 tgtgagccgg cctttgaata tagggaggcg gacggtacag gcttatgccc tgcggcggcg
     5701 catcatcagc gcggccagtc ccagcaggcc cagggaagcc gtggcgggtt ctggaatgct
     5761 ggcgatttca ctcatcagct gaccaacttg ttcctgggaa aggagggagt cgtggatgta
     5821 gagctgttcg atggattcag ccagtcctgc gtccatgaga atctgattaa tttgctggtt
     5881 gccgaatttc aggccgctgt tggaatagta cgtagcgctg tctccaaaat agatgcgggt
     5941 gccaagatct ccggtgacta cggaaatggt cagggaacct tccgtgccca gcggggtgtc
     6001 aacgacgggc ccgctgtatg aggtgttgtt ccataatccc tggagtttcc ggtccgtgtt
     6061 caggcccacg ccccagctta cactgctgtt tttggcgtta aacagagcgg tataggtctc
     6121 cggagtgttg attttggaca ggtcaagaac catcgtcaca gacataacgt cgcggttgtt
     6181 ggcaccgtat ccgttgaagg ttatcccgga caacgtcaga ttgctgtcgt cagacgtgat
     6241 ggaaacggaa tctttccggg tgccgaaatc cgccgtttgg gaggcaaagt ccgaatatcc
     6301 cacgatggag ctatccaaca gagcggtagc cgcggtagcg cttaggctca tgccggccga
     6361 aagaatcagg gtggataata atttattcat ggtcagtatc ttaataaaat gattcaaggt
     6421 tcaatgtatg tacttgtgct tgaataacga atttggaatc cgcaagcaat taaaaatatt
     6481 aagagttagt atattgtatt tataattcat tgaaaataat gattttttaa tatctctggt
     6541 ccttttgcta agatgacggg tcagtctttg ttattcattg gtttcatgat tgatttggcc
     6601 tctttttcat tacttgacgg attccaaatc cgattgggga attccaaatt cgctacaagt
     6661 tgccatccaa aaggaataat aaatatgaag aaaacactga catttttaat cgcgatggga
     6721 agctttgctg tttcctcgga ggcagcgacc gtttttaatt attacactcc cggtacggat
     6781 aattacaata gtaccatcca tgggttttat cttggcctgg ggtcttcttc cctggctcct
     6841 tccgattcct cttctccctc ctccctgtcc ggagagatca gactggacag ttttacgctg
     6901 cgcggagccg ccaacaattt gggcgctaat gtcacttacg gcttcctggt gctgaatggc
     6961 tccgacaatt cggtcatcgg ctggagcacc aatacgggaa ctactgcagc agggattaat
     7021 ctgacgttca gtttttcttc cctggatggt tctcccctgc ttcttgacgc ggcattgaca
     7081 taccgtttcc tggccgtgag ccagtccgtg atggacttga tgcaggatac gtctaaaacg
     7141 tatttatatg ctgcgggggg aacagccgcc cctactgcta acacggaagg agataccgta
     7201 acgatcagcg gcggattgac tgctcccggc atccgcggcc attatgacgc cgagggagcg
     7261 cctggtgatt ctgtcgttat tacgggagcc aacggaacca atactttcag cttattatcc
     7321 ccgattttca cggaaatccg aggggaaatg gtgccggaac cagccacggt ttccctgggc
     7381 ctgctgggac tggccgcgct gatgatgcgc cgccgcaggg cttgagcttc ctgatggcga
     7441 aaaatcggcg gatgagagct gttcttgcgg aacagctctt gttttttata tccagagagg
     7501 aagaattgct tatccgtatg cgggattcat gccctccgga aggtacggaa tttccggggg
     7561 cagggggccg tatccggttt tttccgcatg gcggcaattt gctggaaacg tttttgagac
     7621 gcagtaccgg aaagcttttt ctttaccgga aaatgccgtc aaattcggca gcgcgctttt
     7681 cgtccatatg gtacacagta gctttcacat agcggccttt caggccggat agggatcccc
     7741 tttgcagctc acagacctgg agggccgccg catacctatt atccgccgtc ctattccccg
     7801 gcgctggtat tccggaagaa cggcaatggg ccccatgccc agcacttcat attcttttcc
     7861 atcgtctgcc ctgatgacgg acgttgcatc aacgatgttc ccgacgatgc ggctgccgtg
     7921 gatggcgact gcatcctgct ccgggatgaa ggaaggactg acgcgcatga tatggagcag
     7981 gtaatgttca ttgcagccgg ggacgaaata gtttcagaac gcttctctcg tgacatgttc
     8041 cgtttcggca tggtctgagg attgttccgt tcttaatgca atggtcatga aagattgttc
     8101 tttacggctc ccccttggag aaattccaga ggcggtgcat cgtcataatg tccggaatgt
     8161 tcatggggcg caccacgcgg aacccgatca tgcctccgtc cgtcaggtac cagatgcttt
     8221 tagggttttg aggatcctga cggttccagg cgggggtgct ggcgcggcgc gcagcgcttc
     8281 tcaggctgtc cgggtcgtct tcccacgaac cgccgcgaac gatgtgaggg gcgccgggga
     8341 tgatgactag ggggtctttc gtgggcaagc cgctccgttt gccgtaggca tccggaacgt
     8401 aagagtccaa aacccattcc gccacatttc cgtgcatgtc ccggagtccc cacttatttg
     8461 gttttttaga gcctgttttc tggtagcggt cattggaatt gttccagtac caggcgtact
     8521 ggtccagaga ggcttccccg tttccgtaag aataggcgcc ggcggaaccg gcccggcagg
     8581 cgtattccca ttccgcctcc gtgggcaggc ggtagtaatg cccggtctgg gcgctcagcc
     8641 attcgcagaa tttgctggcg gcgtggtggg acatggagat ggcgggcagg ccgtgttcat
     8701 agccgtggcc catgcccagg ttcatggcgg cgtagggggc ggtaggctgc gtgacggagt
     8761 cccacagttc gtcatccggc tgttcctcca gaagctggcc gtccttggcg cgcggacgcc
     8821 cgttttccat gaaggccgta taaagttccc aggggatttc cgtttccgag atccagaagg
     8881 gagagatgct cactttatgc tgcggacctt cgtccggttt ccggtgcggc tcttccgcgg
     8941 gactccccat gaggaacgtt cctcccggta tggcgatcat gcgcagggaa gctcccgccg
     9001 cgggaaccgt ttccgtgtag gattcaaaac gtgccggatt tccggaagct tcaatgagct
     9061 gatggatttg gcgcgtcgtg ccgaccagct cccgggacgg caggtcatcc ggaatgggaa
     9121 gggcaggacc ggcagcgcgg tccagttccc gtttttgcag cgcggatcgg ctttctcccc
     9181 actggcgtgc gctggtaatg cgcgcggcat cttccgtggc cgggcggggg gaattatttt
     9241 cttcccggca cccggccagc agggcgcttc ctcccagaaa gcaggaaaca aggaaaatgc
     9301 cgcgcatgga atggtgaaaa ccggaatgcc ctacatcgtc atgcctccgt cgcaggcaat
     9361 gacctgcccg gtgatgtaac gggcatcgtc agaggcaagg aaggccgtca gggcggcgat
     9421 atcttccacg gaaccttgtt ctttcaaagg tattttctta acgatttctt ccttgagatt
     9481 gtcgggaatg gcattggaca tttccgtgga gatgaagccg ggagcaatgg cgttgcacgt
     9541 gactttgcgc ggagcgaatt cctgagccag tgatttggtg aaaccgatga ggcccgcctt
     9601 ggaagcggcg taattagcct ggccgatgtt gccgacgaga ccgatgacgg agctcatgtt
     9661 gatgatgcgc ccggccgggg atttcatgag aacgcgctgg agggccttga ctgtattgaa
     9721 cgcgcttttc aggttggtgt ccagaacggc atcccagtct tcctccttca tgcggagcat
     9781 cagggagtcc cgcgtgatgc cggcgttgtt caccaggatg tcaatctgcg ggaagtcttt
     9841 caaaatggcg gccatggttt cctgaacggc cgcgtaatcc gctacgtcgc aggggtaggc
     9901 cttgcaggaa tccggaaatt ccttgttgat ttcttctgcg gcccccccgc agctggatgg
     9961 actgcggctg atcaggatga ccctggctcc ttccgaagcg aagcggcgcg cgacggcatt
    10021 gccgattccg cggcccgcgc cggtaacgat ggctgtttta cctgctaact tttgcatgct
    10081 gcccacagta aacccgtttt tcacggttcc ggcaagcttg aaatggactt ggccgcgcag
    10141 gaacccatac ggggaaaggg cgtgccggga atgaaaaaga ggggggagaa acggggcggg
    10201 gggctactgt ccggcctctt cattttcccg gagtgcatcg gggggcgcac cgttttcatc
    10261 cggttctacc aggtcgctga attcatccga attttccaaa atgtcctttg aggcggcgga
    10321 accgtaatag cgggcctcaa acaggcgttt gccttcctgc ctgcagcggt tgtccagcat
    10381 ttccattcgt ttttccattt tttctatcaa ggcgtcttct ttctcctttt ccgcatcgtt
    10441 caatttatcc tgaagctgga ggaaatgccg gatgtccttc tgaatgtcct gcagcgtttt
    10501 gacggcgttg tccgcgcttt ccttgtcctg aacgcctgcc aacgtctgct ggatattgat
    10561 ggcaaaggaa aaggcctggt tgatcaggga ttccgcggaa ggaatttttt ccgccggagc
    10621 cgctgctgcg ggggaagctg ttccggcggc cgtttcacca aatgcaagag aggctccgga
    10681 cagaagcgca gaatataaga gaggaacaag aaaagccttc atcctgttct tttaaggcag
    10741 gatgaaatcc acggcaagga aaaaggggaa actgaaaaaa gagccttatt ccgccgtgat
    10801 gccgcctttt tcatcgtcca gaatgcctga cttttccaga tagtagtcat atccgcctgc
    10861 gtaggcggtg atggtccccc ggttcacatg cagggttttt tgtgccaggg aacggatgaa
    10921 gtgcacatcg tgggagatga agaccagtgt tccttcataa tgcttcagag cctgcaccag
    10981 ggcttctacg gacaaaaggt ccaggtgggt ggtcggctcg tccatcagca ggaggttggg
    11041 cggatccacc aggaatttga ccaggctgag ccgcgatttt tccccgccgg aaagaacgct
    11101 gacgcgtttt tccacatcca gcctccggaa caggaaggaa cccaggatgg aacgcgcttc
    11161 ttcctcccgg atttcagcgc tgcatttcat gatttcctcc agcacggtat tttccggatt
    11221 caggttttcc gttcgcgcct gggagaagta gccgatgcgc gtcgtggtac cgggagtgcg
    11281 ttgtccggag tcaatgggga tgatgcccgc caggattttg agaagagtgg atttgcccgc
    11341 gccgttcggg cctacaagaa cagtgcgctc cccgcgttcc accagcaggt ccaggttttc
    11401 ataaaccctg cggtcgccat aggattggca gactttttcc agctcaatga ctttctgggt
    11461 gctgcgcgga ggctggggga agttgaattt aaataccttc ctgcgggcta ccggtttttg
    11521 aatgattttc atcttttcca gctgcttgat gcggctctgg acttgcccgg ctttggaatt
    11581 gatggagcgg aaacggtcaa taaattcctg aatgtgcgct atttccttct gctggttgcg
    11641 gtaggccgcc tgaagctgct cgaagcgcac gtccttttgt tggaggaagt ccgagtaatt
    11701 gccgcggtat tccaccagtt cttcgttgtc gatgtcgtac acgctttcca ccagctcatc
    11761 catgaaatcc cggtcgtggg aaatcatcag gatggctccg gggtagtttt tcaggtatcg
    11821 ctggagccac agcagggaca ggaggtccag gtggttggta ggttcgtcca gcatcaggag
    11881 gtccggctcc aggacaagga gtttggccag gtacgcgcgc atgatccagc cgccggacat
    11941 ttcgcgggcg gggcggtgga agtcgctttc ccgaaaggcc agccctttga gaattttctt
    12001 ggctttgggc tccagctggt aaccgttggc ggcgttgaaa gtgtcaatgg cttccgcgta
    12061 ttccggcgta tccgttttgt tggcgttttc cgccgtccgg atggtgtgga tggcctgttc
    12121 catttccggc gtgatgccca gggcgatttc cagaacggtt tcatccttcg gttcgctggc
    12181 ttcctgggga agatagccca cgatggcgta ttcatccatg ctgatggagc cttcgtccgg
    12241 cgtgtcttct cccagaatca tgcggaacag ggtggatttg cctgctccgt tggggccaac
    12301 cagagccacc cgttcccccc agttaatggt catttccgtt tccctgaaca aggtccgtcc
    12361 ggcgtgggat tttgtgagat ttttgatcgt cagcatggtg aagagaggat gtattctacc
    12421 gggatggaaa ggggaaggca agagccgtca gggcggaggc aggcattttt gaaagcttta
    12481 ctggattttt acgcgtagtt tgctagcctt ggcgcgccat gccgaccacg cagacattca
    12541 ggcttttgct tgctgccgcc cttttgtgcg gatggagttc ctgctgtact cctccggcgg
    12601 aggattatat acaacaacct tacgtgcagc agcaaatgtc cgggctggct aatgccttcc
    12661 tggcgctgct gccgccggat caggcctctc ttcccgctgc cggagcggag gccaggtggc
    12721 tggcggacac ggccgtggtc cagtccgccg cgattgcccg ggacaacagg actgtgctgt
    12781 ttggctggct gaacaatatt ctggtcaatt ccaacctgcg cgacaggggg ctgtgctggc
    12841 aggtccagca ggatttgtac cgggacctgc gccgccgccc cgtgaagtat ttccgcatag
    12901 ggctgacgat tcgagaccga ggaacgggca gggagcacag ttgcgtgtat gtcaatgccg
    12961 cggggaaggg attgcagggc tccattgttc tggatgcctg gaagaactgc gggcatctgg
    13021 tgacgctgac ccagaaggac cgggaaggcg gcaaatggga tgaggactgg cgggaaccat
    13081 ttgtttccaa ggcctttccg gagggccatt cctacggcat ggaacatcac ctggtctggc
    13141 ccgggtgggc caggaaacgc cccatgctgg ttcagcggat atttcagtcc gatcagcaga
    13201 atgaggcgaa ggcggccgct gaataaaggg gaagcctgat ccggcaggaa ccggcacacg
    13261 gtgctgcgcc gcggcggttt gcggtatcct ccgtttttaa ggaaaatccc ggcgaatcgg
    13321 caaatggcgg agggaatccg gactcagggc aaataaaaac gcactcagtg cgtacaccga
    13381 gtgcggatta attggataat ttgctagtgt tgcagggcaa aaccccgctg caaacttact
    13441 tgcccttggc ctgcacaacc ggagcgggag caggagcggt ggtttgctgt tgctgctgct
    13501 gctgggagca ggaagcgacc aggcaagcgg cgccggcgat ggcgaggata gcgatgttct
    13561 tcataattcg aattaaatac agtgtttgtt aactactgga acctccgcat ccacggaggt
    13621 ttgctggcac caatgtaaat ggtggcaagt agaaatcaag agattttctt gttccatgtc
    13681 acggcattac agaaa
//
