LOCUS       c00041_gnlPro..        17362 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BDEKBOIK_41.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:22:18
            Original ID  :: gnl|Prokka|BDEKBOIK_41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17362
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17362
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4661:7362]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4662..7362
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17362
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17362
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             130..339
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MLLGDDSLDRLKLGIARLLLDHHANPSLKDKYGRTALQRIGNRSN
                     EHLQMVLKYLPELSAPPLPKKENH"
     CDS             complement(353..1921)
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MKAAPAGYPPNYGGIPKESPAIVRNPLTREFIRVQPIGGFVFLSR
                     GGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKGRRVIVPFHNMGGGT
                     KFHISDDGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVLEMKDGTLWALARTS
                     QDQAWQAFSKDYGETWSKPEPSRFFGTLTMNTLGRLDDGTIVSLWTNTMALPENATAGN
                     GTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHSGYATLDGPEDRGKHQSEMV
                     QLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLNSQWTIHTYIPQKKGHCS
                     YNRKPSAELVQDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGATWNFPNGTTGLVKF
                     RFRVVDGEQADDSGLQVSLTDRLFNACDSTTKDYALFTFPIRLKPAPHLLLGMKKVPFS
                     PGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGASYIHFISTGSQPDAGILLDTV
                     NARVK"
     CDS             complement(1918..2091)
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MPNRRPHPFRSLKLSPLRRLMRGAALSVWTPVKYAIIPVPARNRI
                     TWSAGITEKHGK"
     CDS             complement(2225..3013)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_4"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 5.3e-23, bitscore:
                     72.4, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSYMLAILLGSSSLAFSAPSIPASALPVTLKPEPHQRDPYDW
                     NARHEAVKKRNRAVKPEYVMIGDSITHHWGGEPSGDGKNTGSGSWEKLFGPHAATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAGLHNGKDIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             complement(3236..3991)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_5"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 7.1e-24, bitscore:
                     75.2, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLAGVFCVACFSGACADELPPTLKPQVNPRAVYDWKKRHEAVMER
                     NRTVKPEYVVFGDSITHRWGGEPSGDNRALGTGKTAWDSLFSSHAVTNMGFGSDYVDNA
                     YYRLQLGELDGISPRVIIVLLGTNNLGGRKDAPRVCADNLKAFVSLARRKCPSSKILLL
                     GILPREEKKLAPLIRETNKMISGLADGNSVFFANPGEEFLGEDGVSPKPGLLEDGLHPS
                     ARGYDILGKSLSVLLKKMDDKYGKLPAPR"
     CDS             complement(4050..4148)
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="LACFTCLSVAERKMRGTCDCGKVTEDYFSLLS"
     CDS             4662..6566
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_7"
                     /sec_met_domain="Gly_radical (E-value: 5.5e-46, bitscore:
                     145.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.5e-243, bitscore:
                     799.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDIRAA
                     RSAGIITGLPDAYGRGRIIGDYRRVALYGTDKLIAERRKDLKNREHSPLTDELIRLREE
                     MSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGRVST
                     FFDIYFTRDLEQGLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTESIGG
                     MGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPETFKSFCAKVSIETSSVQY
                     ENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGKQVA
                     PPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHDPEI
                     LRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVDDIA
                     CSLVSNFMEKLRRLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGANPM
                     HGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAYFAA
                     TGHHINVNVLERETLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFHTR"
     CDS             6583..7362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 53.6;
                     E-value: 9.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_8"
                     /sec_met_domain="Radical_SAM (E-value: 1.1e-31, bitscore:
                     100.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQVFPQNRDPDGESSVTGLVHSVESCGTVDGPGIRFVLFLSGCS
                     LRCRYCHNPDTSYVRRGRLRSADDVLKEIARYRDFLQAAGGGVTLSGGDPLFQPDFAGA
                     VLKGCRKLGLHTCLDTSGHLGVNAGEEMLADTDLVLLDIKAWNPKRYRALTGGELRPTL
                     EFAERLASLRKPVWLRYVLVPGVTDNLEEIEELSRHAALLGNVERVDVLPFHQLGRFKW
                     DELKLDYTLKDVPEASAELAEQVRGIFRRGGFPDCVH"
     CDS             complement(7609..9534)
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     RAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSRSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDRFAPQDKKAAALLENMELKPYRILVAVPRALDEAL
                     ATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVLEVTHVLPHDSLKQLREALAADEFYN
                     DGPLDLGVMLDGDMETLKALEPYGPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQ
                     LYLQLGGLHGLDVATPSLFPVKKAAPAEDAPILIAPFSRLGSASEWSWEQWRELVSLLP
                     GRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDFPSLCSFRG
                     LPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVRDVLEALR
                     EISGKE"
     CDS             complement(9527..9685)
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MGWLWIPHRCKNLGKTSFSRENKMREGISAGGIKGLWTGGDSYNI
                     FSGFPYD"
     CDS             10073..11212
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_11"
                     /sec_met_domain="Abhydrolase_1 (E-value: 6.4e-30, bitscore:
                     94.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPAVQTKFLDLPNSFSLRNGATLDKVRVAYEQYGTLTPNKDNA
                     ILLFHALSGSQHAYGYNPEVPGIGSLWKPENHEGWWNSIIGPGKPLDTNRFCIICANYL
                     GGCYGTTGPATPCPADGQPYGSRFPHVEAADQARLQALLLDSLGIERVHLMGPSVGGLI
                     ALSFACQFPERVRSFISIGSGYRASIEHRLSLFEQILAIELDPDFQGGDYYRGPAPKKG
                     LAFARIIGHKSFVYQEGLEQRARKEVGGNYGLLTWMTPTRSTQSYMLHQGTKFAERFDA
                     NAYIRIADMWAEFDIRDHTPDGTFQTALEGFRRAGIPALIFSIDTDCCFRPAEQQDFAA
                     QLEAAHIPTEFHTIASTKGHDSFLLEPELYAEPIRRALG"
     CDS             11485..11709
                     /locus_tag="ctg41_12"
                     /transl_table=11
                     /translation="LKNTAENTWSGPNEIIPLISGWKTNRVIVIRIPSRESLECCFASE
                     EYRQLKSLREDSVDSHAIIVKGTDYDETL"
     CDS             11804..12034
                     /locus_tag="ctg41_13"
                     /transl_table=11
                     /translation="LIPAWTEARRPFFSYMEETGQRPEEIKGIFLTHAHPDYIGSASRI
                     REMEMGPVHTQIIPYFILYFPINNFRAKSRV"
     CDS             12058..12852
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_14"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 8e-23, bitscore:
                     71.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCLFLKKFVSLFILPLLGLLSLHAEEVPSSPPPAPLVIDGIPAN
                     QVQLVLIGDSITDDLRQNKKPLHEFQPVWQKYYAPYKALNLGVSGNKTSDVLNRINNGM
                     LDHIKPRVAMLMIGTNNTGAGESVEDTVKGIQSVVDKIHEKLPSTRILLLNILPNDIRD
                     WHVRGAQDPKEKWLKDREINKQINAFYVNSSFVTCLNLEKVFLNKDGSINETLYYDPQE
                     VNFLGRKCGPLHPSTAGHTLMAEAIKPVLKKLMEKPALSPEQ"
     CDS             complement(13207..13665)
                     /locus_tag="ctg41_15"
                     /transl_table=11
                     /translation="MNGRDFFKDNFKLGLTFLMAAYFHSHSMGVSRSGRSAWRTGQDKA
                     VFSSMARRGWLPSRGMITFSSIFSIPLDDSAARARTRMPFKSTPFLAATTETRLIMQEA
                     SVEPSKTPGEGNSARPSKEAGRSVANVTLEGIKVVSQRNCPTFSVSEV"
ORIGIN
        1 ctggctttca ttgatgtgtc ctgcctccct caaatcaggg acctggtcaa tctcttcatc
       61 aaagagggag ctgacgtcaa ccatcaaaac gccgccggag aaactcccct catggcatgc
      121 tgccgaggca tgctgctggg agacgattcc ctggaccggc tgaaactggg tattgcgcgt
      181 cttctgctgg accaccacgc aaacccatcc ctgaaagaca aatacggacg cacagccctc
      241 cagaggatag gcaaccggtc aaacgaacat ctccagatgg tgctgaaata cctgccggaa
      301 ttaagcgctc cgccgcttcc gaagaaggaa aaccattgaa tcccgccgct ccttacttca
      361 cccgggcatt caccgtatcc agcagaatgc cggcatccgg ttgggacccg gtgctgatga
      421 aatggatata actggctcca ttgggggact tattagccat tttcaacgtt ccggccttct
      481 ttccgtccag agacaccacg gcctgcccac cctgccaaag aagggaaatt tcatgccacg
      541 cgccgggcga gaaaggcact tttttcatcc ccagcaacag atggggcgca ggtttcagcc
      601 tgatcgggaa ggtaaacagg gcataatcct tcgtagtgga atcacaggca ttgaacagcc
      661 ggtccgtcag agagacctga aggccggaat catccgcctg ctccccgtcc actacacgga
      721 agcggaattt gaccagccct gtggtcccgt tcggaaagtt ccaggtagct ccgccgttcc
      781 ggtaatccac attggatttt tcattgacca gttcgggatc atccagacgc ttgatttgca
      841 acaccttctt cgttcccccg gacggatcct gaaccagctc ggcggaaggc ttgcggttat
      901 aactgcaatg gccttttttc tgggggatat aagtgtgaat ggtccactgg gaattcaaat
      961 ctttccccgt ctgcgtggca cgcgtcttgg cccctaccca gcggcggtcc acaataacca
     1021 ggcggcggtg gtttttatgc tgccccaggg aaataaggat gcggtttttg tccagctgca
     1081 ccatttcgct ctggtgtttg ccgcggtctt ccggaccatc cagcgtagca tagccggaat
     1141 ggttgcggtg ttcgtccagg atgatctccc ggaacccgta ccaggttttg ccctcgtccc
     1201 cggacatagc aatgtggtgg gaatcacggt tggtgaatac atcctcccac gttccgttgc
     1261 cagctgtggc gttttcaggc agagccattg tattcgtcca cagggaaacg atagttccgt
     1321 catccaggcg tcccaacgtg ttcatggtca gggtgccgaa aaagcgggaa ggctccggtt
     1381 tgctccacgt ttccccgtaa tccttggaaa aagcctgcca cgcctggtcc tgggaggtgc
     1441 gggcaagcgc ccacaacgta ccgtctttca tttccaaaac cgtggcttcc acggcattgt
     1501 tgaaccatct gacgccctgg tgggggggcc tggcttcatg tctgggggaa gtaacaccgt
     1561 tcctggatac atgccaggtc agccccccgt catcggaaat atggaacttg gtgccgccgc
     1621 ccatgttgtg gaacggcacg atcaccctgc ggcccttgtt cacaaaaacg ggggttcgca
     1681 tgatgccgcc cagttttttc aggtttttcc tcttttccgg gtctttccag tcttcttcca
     1741 gtttgccgtc attcgtgacg gcaagccact tgccgtccag cccacccctg gaaagaaata
     1801 caaagccccc gataggctgc acacgaatga attccctggt caaagggttg cgcacaatag
     1861 ccggagattc cttgggaatg ccaccgtagt tgggagggta gccagccgga gcggccttca
     1921 tttcccatgt ttttccgtta tccctgctga ccaggtaatc cggttccttg cgggtaccgg
     1981 aataatggcg tatttcacgg gagtccacac ggataaggcc gcgccccgca tcagccggcg
     2041 gagtggcgac aacttcaggc tccggaacgg gtgcggcctt ctgttgggca taacagcaac
     2101 aaaaggaacc ggtcaacaat gcaaacaaca ggtttttcat aaactaaata tcaaaggcca
     2161 tatattttcc tcaaccgggg ctttcccttc aagcagaatc ctaccttcca tcagaagacg
     2221 atcatcagga atgctttccc gcctgcttcc ctccccggta ttttgcatca agctttttca
     2281 ggagtacggc cagttccttt tccaaaacct cgtaccccct ggcattggga tgcaccacat
     2341 ccttcatgaa ttcattctgc ggagaagcac cgtctgcgga aagaagcgcc tttcccggat
     2401 cggcaaagaa aatgtccttt ccgttatgca gccccgccaa cagtctgttc gtctgcttca
     2461 ccggttccgc caggtttttc tccttccgtg ggagaacgcc cagcaacagg attttggaag
     2521 aggggcactt ccggcgcact aggcggacaa atgccctgat attgtccgca catgcctgcg
     2581 gcgtatcctt gcggtgtccc agattattgg tccccagcag cacgatgatg acccgcggag
     2641 aaatgccgtc cagctccccg ttttggacac ggtaataggc attatccaca taatcaaatc
     2701 caaagcccat attcgtcgct gcatgcggac cgaataattt ctcccaggaa cccgatcccg
     2761 tattttttcc gtccccggaa ggctcccctc cccaatggtg ggtaatgctg tcccctatca
     2821 tcacgtattc aggcttgacg gcccggtttc tttttttaac ggcttcatgc cgggcattcc
     2881 aatcatacgg gtcccgctga tggggctccg gcttcagggt aacgggcaac gcggaggccg
     2941 gaatggaagg cgcagaaaac gccagactgg aactccccag caatatggcg agcatgtagg
     3001 agaggaaatt cataatcaaa aagtaaaacc ggttttcagt ttaagcaaat tctgccgtgc
     3061 atcaagatcg caggcgtcac ttccgccggc agagtaaaaa agaccactgc ccgtccggca
     3121 aatcctgccg caaccacggc caggcgagca ccgtgtccgg cctcttccaa ggcgcgctcc
     3181 atttcatcca tcccccggcc tctcccggaa caggaacgcc ctcccccgta ttcatctacc
     3241 ggggagcggg cagcttgccg tacttgtcgt ccattttctt cagcaatacg ctcaacgact
     3301 tccccagtat gtcgtacccc ctggcactgg gatgcagccc atcctccagc agcccgggtt
     3361 ttggggacac tccgtcctcc cccaggaatt cctcgccggg attggcgaaa aacacgctgt
     3421 ttccgtcagc caggccggat atcattttat tggtttccct aatcagggga gccagctttt
     3481 tttcctccct ggggagaatg cccagcaaca ggattttgga agaggggcac ttccggcgcg
     3541 ccaggctcac aaaagccttg agattgtctg cgcagacccg gggagcatcc ttccgcccgc
     3601 caagattatt ggttcccagc agcacgatga tgacccgcgg agaaatgccg tccagctctc
     3661 ccagctgcaa gcggtaatag gcattatcca cgtaatcgga accaaacccc atattggtta
     3721 ccgcatggga agaaaacagg ctatcccagg cggtttttcc tgttccgaga gccctgttgt
     3781 ccccggaagg ctcgccgccc cagcggtggg taatgctgtc accaaagacg acatattccg
     3841 gtttgacggt ccggttccgc tccatcactg cttcatgacg ttttttccag tcatacacag
     3901 cccgcgggtt cacctggggc ttcagcgtgg gcggcaattc atcagcacag gcaccggaga
     3961 aacaagcaac gcaaaaaact cccgccagca ataaacaaag gcatgcataa gatttcataa
     4021 cggtaagcgt tgagatactg caatagagat taggaaagta aagagaaata atcttccgtc
     4081 acttttccgc aatcgcatgt tcccctcatt ttccgctccg caacggacag acaggtgaaa
     4141 catgccaaag ccagcgcacc cgcgttctct tcgcaaagaa ttagccttgt tgtcccccgg
     4201 aattcacgat ataattacgc ggcgcggagt tttgccgttt ccagcctttc aggggctgcg
     4261 gaacgttttt ctccagtctt cttcactaca ttctatttat gatcagcata gtaaaagact
     4321 tgaaggagtc caccgccctt ccgcaggaat ggcagggatt caagccggga acatggacgg
     4381 agtccattga cgtacgggat ttcatccagc ataactacac gccctattcc ggcaatgaag
     4441 agtttctttc cggcccctcc cagcgcacgc ttcgtttatg ggacgagctg aaagtcctgc
     4501 tgaaacggga aatagacaac ggcggcgtgc tggatgctga tgaagaagtg gtatcctcca
     4561 tcacatccca caagcccggc tacattgaca aggaactgga agtggtcgta ggcctccaaa
     4621 cggacgcccc cctgaaaagg gccctgatgc cctttggcgg cttgcgcatg gcccaacagg
     4681 ccctggaatc ctacgggttc aagatgtgcg agaaaaccgc ggacattttc aaaaagatac
     4741 gcaagacgca caatgaaggc gttttcgacg cctacacttc cgatatccgg gcggcccgtt
     4801 ccgccgggat tattaccggc cttccggacg cctatggccg cggccgcatc atcggggact
     4861 accgccgggt ggccctgtac ggcacggata agctgattgc cgaacgccgc aaggacctca
     4921 aaaaccgtga acattccccc cttacggatg agctgatacg tctgcgcgaa gaaatgagcg
     4981 aacaaatacg cgccctggaa gaactcgccc agctgggcgc ctcctacggc tgcgacctca
     5041 ctcgccccgc cgcaaacgcc cgcgaagccg tgcaatggac gtacctgggc tacctggctg
     5101 ccgtgaaaga acagaatgga gcggccatgt ccctgggccg cgtttccact ttcttcgaca
     5161 tttatttcac ccgcgacctg gaacaggggc tcatcacgga agaggaagtt caggaaatca
     5221 tcgaccagtt cgtgatgaag ctgcgcatcg tccgtttcat ccgcacgcct gattacaata
     5281 acctgttctc cggagacccc acctgggtga cggaatccat cggcggcatg ggagaggacg
     5341 ggcgcaccct cgtcacccgc agttctttcc gcatgctgca gaccctgtac aacctggggc
     5401 cggctccgga accgaacctg accgttctgt ggtcccggaa cctgccggaa accttcaaaa
     5461 gcttctgcgc caaggtttcc attgaaacat cctccgtcca atacgagaac gatgacctga
     5521 tgcgcccgca ttggggcgac gactacggca tcgcatgctg cgtgtccgcc atgcgcatcg
     5581 gcaagcagat gcagttcttc ggagcgcgcg ccaacctcgc caagtgcctt ctctacgccc
     5641 tgaacggcgg cgtggatgaa ctcaagggca agcaggtggc cccgccctcc ccccgctaca
     5701 cggaggaaat tctcaactat gatgaagtga tggccctgta cgacaagatg caggactggc
     5761 tcgccaaaac ttacattgac gcgctgaaca tcatccacta catgcacgac aaatactgct
     5821 atgaacgcat tgaaatggcg ctgcatgatc cggaaattct gcgcacgatg gctacgggaa
     5881 tcgccgggct ttccgtggcg gcggactccc tgtccgccat caagtatgcc accgtaaaag
     5941 ccatccgcaa tgaagaaggg ctgattgtgg acttcaagac ggaaggggaa ttcccctgtt
     6001 acgggaacaa tgacccgcgc gtggacgaca tagcatgcag cctggtcagc aatttcatgg
     6061 aaaaactgcg caggctccac acttaccgca attccctgcc cacccagtcc atcctgacga
     6121 tcacctccaa cgtggtgtac ggcaaaaaga cgggcaacac gccggacggc cgccgagccg
     6181 gggaaccgtt cgcccccgga gccaacccca tgcacggaag ggacaggaac ggagccgtgg
     6241 cctccatgct ctccgtagcc aagctgtcct atgacgactc cctggacggc atctcctaca
     6301 ccttctccat cgttccccag gccctgggca aggaggaacg tgaacgccgc gtcaagctcg
     6361 tctccctgct ggacgcctac tttgccgcta caggtcacca cattaatgtg aacgtactgg
     6421 aacgggaaac gcttctcgac gccatggatc acccggaaaa atacccgcag cttaccatcc
     6481 gcgtttccgg ctatgccgtg aatttcatca agctgacccg ggaacagcag caggaggtca
     6541 tcaaccgcac tttccacacc cgttaacccg gactgcaagc ggatgccgca ggtttttcca
     6601 caaaaccgtg atccggacgg agaaagctcc gtcaccggtt tggttcattc cgtggaatcc
     6661 tgcggcaccg tggacggccc tggcatccgc ttcgtccttt tcctgtccgg ttgcagccta
     6721 cgctgccgct actgccataa tccggatacc tcctacgtgc ggaggggccg gctcaggagc
     6781 gcagatgatg tcctcaagga aatagcccgt taccgggatt ttttgcaggc ggcgggcggc
     6841 ggcgtcaccc tctccggcgg ggaccccctc ttccagccgg attttgccgg tgccgtgctg
     6901 aaaggctgcc ggaaactggg cctgcacacc tgcctggaca cctccggcca tctgggcgtg
     6961 aatgcgggcg aagaaatgct ggcggatacg gatctggtcc tgctggatat caaggcatgg
     7021 aatccgaaac ggtaccgcgc cctgacagga ggggaactgc gccctacact ggagtttgcg
     7081 gaacgcctgg cctccctccg caagcccgtg tggctgaggt atgtgctggt acctggcgtt
     7141 acggacaatc tggaagaaat tgaggaactc tcccgccatg cggcgcttct gggcaacgtg
     7201 gaacgcgtgg acgtgctccc tttccaccag ctggggagat tcaaatggga tgaattgaag
     7261 ctggactata ctttgaagga cgtcccggaa gcgtccgcgg aactggcgga acaggtccgc
     7321 ggcattttcc ggcggggcgg ctttccggat tgcgtgcatt aaccggattt tcgcgctttg
     7381 gcgccaccaa ccgcagcaaa ccggacgcag gcattcccct cttccggatg agaggcctct
     7441 tccctccact acagaatcca tgcaaaaagg aagacgcatt tctggaattg ctccggaata
     7501 cggcatttcc gcaattcctt tcgttattcc atcattcttt acggcaacgg cagcattccc
     7561 gccatttttc cgccaacgcc gggggacggc attccgtccc ttcccagatt attctttccc
     7621 ggaaatttcc cgcaaggctt ccagtacgtc ccggacggca atgtggcggt tgcagggaac
     7681 atcccggtca cattccttcc ggaagcaggg agaacagcac tggtggctgt aaagggaacg
     7741 gttgaatgtg cccatagggc ggtaaacatc cggaagccgg gtggaaaaca gagtcaccac
     7801 cggaagcccc cggaaagaac agagggacgg aaagtcgcca tccacggcta ctgccgccgc
     7861 agcgccgtcc atgacgggaa agagagcttc cggcgcaccc accgccagct ccacattcaa
     7921 atgttccgcc agggacgcgg cgcgctcccg gtcttcttcc agagccgcca gcaccgtccg
     7981 tcccggcaga agggaaacca gctccctcca ctgctcccag ctccattcac tggcgctccc
     8041 caggcgggaa aacggagcga ttaaaatggg ggcatcttcc gccggggccg cttttttcac
     8101 agggaacaaa gacggggtgg cgacgtccag cccatgcagc ccccccaatt gcagataaag
     8161 ctgcacccgg tgcgccgggg gggcggcgcg caggacgggg gcctttaccc ggaatttgta
     8221 cttccgggca ccgggatgcg tgtccagccc ggaaaacatc atggggccat acggttccag
     8281 cgctttcagg gtttccatat ctccatccag catgacgccc agatccagcg gtccgtcatt
     8341 gtaaaattca tctgctgcca aagcttcccg aagctgcttc agggagtcgt gcggcagcac
     8401 atgggtaact tccagcaccg tcttccatat ccccagctgg gcagacgggc agacgatgtt
     8461 cacctgcatg tcgcaccgga cggttttcaa agcacgaatc aggggaacag tcgccagggc
     8521 ttcatccagc gccctgggaa cggctaccag aatgcggtac ggcttcagct ccatattttc
     8581 caggagcgca gccgcttttt tatcctgcgg ggcaaatcgg tcaacggatt tccagcggtg
     8641 gtgcatccag aacacatcca gcacggattc ccggatcaac gtttccagcc ccctgttcac
     8701 ttcaatcgtg tcccccgcca gagaaccgtc cgacctggaa aaatccacca cattccccat
     8761 atccgctatc cagtggccgg gagcatccgt gcgcactgct atggccacca tgtccgcgcc
     8821 agcccttttt ctcagcagag cgggcagcgg agtcgtgccg gtcaccttgc caaaaaaggg
     8881 gacatacacc ccctcccata caaactggtc gctcagcacg cccagggccc ccccttcctt
     8941 gagcattttc atgggagcct tgatgcctcc ctccttggag aacatctgag ttccacgttc
     9001 cgtgcgccgc tggtacacgt attcctccat cagcggattg tcaaactggc ggtacatgga
     9061 cccgtaacgc tccacctccg ggtaaaatgc gcgtattctc gccagcgcct cccagttgcc
     9121 ggagtgggct atggcgcaaa cctgcccgcg cccttccagc acaggcgcgg caaactgttc
     9181 gtgccctccg accgtcacgc aatgcttcaa ttgctcatcc gtcagggtag ccgtcttcgc
     9241 ggaacacagg aaattggcaa tggtcctttt gaaattttcc cggcttaatt tctgcagttc
     9301 ctttccgcgc agggccggat ccaaaacgat gcgcagattc ctttccacaa tgttccggcg
     9361 ctggggaagc agatgccacg ccacggcccc tgccgcgcgc cccagccggt acagcgtttt
     9421 catgcccacg agcttcaaca gcccttccat gagcagaaac cctttcattc ccaaatgatg
     9481 ggcaaacgta ttccgggaag ccggggagga atcaggagag gaagaatcag tcataaggaa
     9541 aaccggaaaa gatgttatac gaatcccctc cggtccacaa accctttatt cccccggcag
     9601 agatcccttc ccgcatttta ttttcccggc taaatgacgt cttccctaaa tttttacatc
     9661 ggtgcggaat ccaaagccat cccatgcttt actgcatctt cctcataaaa gcatctctgc
     9721 ggaggcggca tcttactttt ggcaaagaaa tgactttaca attcttaact aaccggtata
     9781 ttccgtctcc cgaaccgaac accaaaccgg agttatacac catgaaagtt ctttcttcct
     9841 tagcctctat gaagcgccgc cacgcagact gccaaatcgt gaagcgcaag ggcacgctgt
     9901 atgtgatctg caagagcaat cccaagttca aggcccgcca gggcgctacg gcaggcacgc
     9961 gcctttccaa aaagggcgtc aagtaatccc tggcccagca cagatttcaa gaagaccgcc
    10021 gcccgccggg tgccggtctt tttttgctga ccaagcccct ttccgtacat ccatgcagct
    10081 tcctgccgtc caaaccaaat tcctggatct tcccaactcc ttctccctga gaaatggagc
    10141 tacgctggac aaggttcgcg tcgcctacga acagtacgga accctgacgc cgaataaaga
    10201 caacgccatc ctgctgttcc atgctctttc cggcagccag cacgcctacg gttacaatcc
    10261 ggaagtcccg ggcatcggtt ccctctggaa accggaaaac cacgagggct ggtggaacag
    10321 catcatcggc cccggcaagc cgctggacac aaaccgcttc tgcatcatct gcgccaatta
    10381 cctgggaggc tgctacggca ccacaggccc cgctaccccc tgccctgcgg acggccagcc
    10441 ctacggctcc cgcttcccgc atgtggaggc cgcagaccag gcacgtctcc aggcccttct
    10501 gctggacagc ctgggcatag aacgcgttca tcttatgggc ccctccgtgg gcggcctgat
    10561 cgccctcagc ttcgcgtgcc agttcccgga acgggtccgg agcttcatct ccatcggctc
    10621 cggctaccgg gcttccattg aacaccgcct gtccctgttt gaacaaatcc tggccattga
    10681 gcttgacccg gatttccaag gcggggatta ctaccgggga ccggcgccca aaaaagggct
    10741 ggcgttcgcc cgtatcatcg gccacaaatc atttgtttac caggaagggt tggaacagcg
    10801 tgccagaaaa gaggtgggag gcaactacgg cctgctcacg tggatgaccc ccacccgcag
    10861 cacgcaaagc tacatgcttc accagggaac caagttcgcg gagcgctttg acgccaacgc
    10921 ctatatccgt attgcggata tgtgggcgga gttcgacatc cgcgaccaca ccccggacgg
    10981 aacatttcaa accgctctgg aaggcttccg ccgcgcaggg attcccgcgc ttatcttttc
    11041 cattgataca gactgctgtt tccgcccggc ggaacagcag gatttcgcgg cgcagcttga
    11101 agccgcccat attcccacgg agttccatac catcgcttcc accaaggggc acgattcctt
    11161 cctgctggag ccggaacttt atgcggaacc catccgaagg gctctggggt gagcgtgcgg
    11221 ttctccagaa ggttttcccc ctgatcgtcc cggcagattg acgcaggata tccctgcttt
    11281 aatcttcccg tcaaggccat caatgcttct ggggaatgca tggaaaccaa ccgacaacca
    11341 tcaccgcgca tttcatgacg gcagccacat ccactgctta tcaggaaaaa aggatatgag
    11401 ttattatttt atcgtcacga tttcattaac cggagatgcg catacccctt atgatgccta
    11461 cgtcagggag ataaaagccc attgttgaaa aacacggcgg agaatacctg gtcaggacca
    11521 aatgagatca ttccgttgat ttctggctgg aagacgaacc gtgtgattgt catccggatt
    11581 ccctccaggg aaagcctaga atgctgcttt gcatcggaag agtaccggca gctcaaatcg
    11641 ctgcgggagg attccgtgga cagccatgcc atcatcgtga aaggaacgga ttatgatgaa
    11701 actttgtgaa ggactgcacc agctcagggt tgatttccgg gtgacaccgg aaatcaggag
    11761 gtttgcgtat acttattgat tgagggagac gcctgctatc tgattgattc cggcatggac
    11821 ggaagcgaga aggccgtttt tttcctacat ggaggaaacc gggcaaagac cggaggaaat
    11881 caaagggatt ttcctgacac acgcccaccc ggactacatc ggcagtgcgt ccagaatcag
    11941 ggaaatggaa atggggccag tccacactca aatcattcct tattttatcc tttattttcc
    12001 aatcaacaat tttcgcgcta aaagtcgcgt ataaaagaac aacgacattt tatttttatg
    12061 aactgccttt ttctgaaaaa attcgtttct ctgtttatcc tgccccttct ggggctgctc
    12121 tccctgcacg cagaagaagt tccctccagc cctccccctg cgcctcttgt catcgatggc
    12181 attcccgcca atcaggttca gttggttcta ataggcgact ccataacgga cgatttgcgt
    12241 caaaacaaaa agcccttgca tgaatttcaa ccggtctggc aaaaatatta cgctccctac
    12301 aaggcgctga acctgggagt gagcggaaac aagaccagcg acgtgttgaa ccgcatcaac
    12361 aacggtatgc tcgaccacat aaagccgcga gttgccatgc tgatgatagg aacgaacaat
    12421 acgggagccg gagaatccgt cgaagacacg gtcaagggca tccagagcgt cgtagacaaa
    12481 atacatgaaa aactgccgag tacccgcatc ctcttgctga acatcctccc gaacgacata
    12541 cgagactggc atgtaagggg agcccaggac cccaaagaaa aatggcttaa ggatcgggaa
    12601 attaacaagc aaatcaacgc cttttatgtg aattcttcgt ttgtcacctg cctcaatctc
    12661 gaaaaagtct ttctgaacaa ggacggcagc atcaatgaaa cgctttatta cgatccccag
    12721 gaagtcaact tcctgggcag aaaatgcggt cccctgcacc cttcgacggc tggccacacc
    12781 ctgatggcag aggccatcaa acccgtcctg aaaaagctta tggaaaagcc ggcactctct
    12841 ccagagcaat aatgccatcc ctctccggga gctatccttt cacttatcag agcctaaagg
    12901 cattagtctt cattcatgga atccagcgcg gaaccgggca tggagaggtt cctgagaaat
    12961 cccttctttg ccaggacgct catctccctc ctgcccggcg gcatgcagaa catttttccc
    13021 tgattgcagc catggtccga aaaaacgcag aagagcaccg ggggaagtac agccttgagc
    13081 gcaaagccca ttaatcgtcc atcgctacag ccagccaaat tttcacaata tccttgataa
    13141 aaaattacca aattccggtg aacccaaatc ggggttgagc tgtcccactc ctatgactga
    13201 tactcattac acctccgaaa cggagaacgt cggacaattc cgctgcgaaa ccacctttat
    13261 tccttccaac gttacgtttg ccacggacct gcccgcttct tttgaaggcc gcgcagaatt
    13321 cccctccccc ggagttttgc tcggttccac gctcgcctcc tgcatgatga gcctggtttc
    13381 cgtggtcgcg gccagaaaag gagtggattt gaaaggcatg cgcgttctgg cgcgtgcggc
    13441 ggaatcatcc aagggaattg aaaaaattga actgaaggta atcatgcccc tggaaggcag
    13501 ccaccctctc cgcgccatgc tggaaaaaac cgccttgtcc tgccctgtgc gccaggcgct
    13561 gcggcccgat ctggaaacgc ccattgaatg ggaatggaag taagcagcca tcaggaacgt
    13621 caacccaagc ttgaagttat ccttaaagaa atcccgccca ttcatgaaaa aagccgctgc
    13681 ggaatcatcc gcagcggctt tccaattggc cgacgttttt tcctttagaa gttgtagcgg
    13741 tagccgatac tcccgttgat ggagctggaa ccgctgcgga tatccgcatt gccgtccaca
    13801 aaaatgacgc cctgggtgcc cacgggaacg ctcagccccg cgccaatctg gaaggccgtg
    13861 cttccgacct tggcgccata caccggacgc gtataggagg gatctgccag gaagcccaca
    13921 ttagcctgcc cgcggcggtc tcccatatcc tgggaaacgt tcacccgtac ttctcccagc
    13981 gcttcacgcc cgaagatatt ggaccccatg agtccggaga gccgggcacc cacagcgaca
    14041 gcagccgtag tcagttcctg gtcttccacc ttcagtccgg catttccggc agaaccgctt
    14101 tcccgatagc cgtccatgcg ggtcgtcacg atggaagcgt taaacaaagg ctggagaatc
    14161 acgctcctgt cttcattgag agcgatgtca tacgccaact cgtacatggc gccgaaaccg
    14221 gctcccgtcg tattgccgcg ggcctggtaa gaccccgtac cgtaattcac cgtgcgcgtc
    14281 agcgaggcat cattccagcc acccgtcaga atcagcagat gggaccattt acggtactgg
    14341 tagcgggcga acagattgac atagtaactg tccaggtctc cgtccgccgt atccgccgcg
    14401 ctggccgtca ggcttccgta attggcagta aacgcagctc ccgcagtgag gcggtcgttg
    14461 atatccacgt ccatgcctac cgtgcctccc caggtggtga gttcgtagcc gctttcatcc
    14521 cccctggtgt ccagcttggc ataagacccg gttccctgca tccacatatg gaagtagggc
    14581 atgtcttcat ggacatatgc agggttaacg cccatctgcg ccacgcggtt gcgtatccag
    14641 cccatctggt cgcgcaggga gtcgcgctgg gcgatgccca ggctggtaac cgtgctgccg
    14701 gcggcggcgg ccagtttgcg ggcggcgccg gaatagtcgc ctgaattctg ggagagaaga
    14761 acagaggtat agaaatcgcg caaggcagag ccttcctcca tgtgatagcg ggaattccaa
    14821 aggatgtccg ctccagtagc ggcattccgc gtcagggaag agtcacggaa aatgttttcc
    14881 gtgcgcgccg taccggtgag gatgatggcc gtcatgctgt cattggtggt cagctccagg
    14941 ttttcataca tggaaccaag aatcatgtcc tggagggtga cattgtcacc cagggacacc
    15001 agcgcgccgt ccgttgtctt gaacaattcc atattcagcg tttccgaact cccggaaacc
    15061 agggtatcca gattgttcat gaccagcgtg acttcccccg tcccgtctcc cagcgtaata
    15121 tttccgctgg aggtgacaaa gggattgccc aggccgtcca ccgttgtgga ggaagtggta
    15181 atggccactg tgctgtcccc tgtcacgctc aagccgtccg agccaagcgt cagctgggtt
    15241 ttgggatcgt ctgcgctgcc gatattgagc gtgccgccgt tcacggtaat cccctgatag
    15301 gaagcctggg cgggattgcc gccctcccct gccgttccgg ccagggtcag cacgccgccg
    15361 tcactcacat tcaggtgata acctgcattg cccgcaccct tgatagtctg gacgcttccg
    15421 ttgccggatt tgacgttgag cgttccggat gccccgtcca gagtaccggt aaaggtatgg
    15481 gaatcggaag agctgatcgt catttccgca ccgctcagct tcagagctcc gccgccctcc
    15541 agtccggaaa cggtattcac ggaaccggtt gcagcggaca gggcggaccc ttcacggata
    15601 tccagcagga cactgttcag ggaagagccg ttgcccagtg tcagggagga gtctgttccc
    15661 gtaccaccca aggtcagcgt accgtccccg gagatagtca cttccgtgac atggctgccg
    15721 gcctgctggc cggtaagaac catctgggct ccgttaccca aattcagggt tccccctccc
    15781 gcgccggcag ccagcgtctc caccgtggtt acacgggagg cgccgtcatt ccgtccgccc
    15841 agcgttatgt ctccgcccgc gagttccagc gtagtaaggc tattgcctgc accgttcagg
    15901 atgatatttc cctccgagga actgagactg gagtcattcc cggtgaagtt tccttctacg
    15961 gtgagggttt ccgcaccttt cttgacaaaa tccacatggt ccccgctgat ggttccgccg
    16021 tagctgttgc cgccggcgtc aacatcctga accagatcca ccacggcgtg gttggaagcc
    16081 gcatcatccg ccgtattcgt cacggtcagc gcaccgtcgc tgccaaccag gttgctgact
    16141 ttcagaccgt ccccattccg ggaggcttcc ggagccccgt tcaggctcac atgaagcgtg
    16201 gtgccattaa tgccgacagc cttgtaggga tccagcgcgg cgtaatcgct gatattgggg
    16261 ttgtctgaat tgggggtggt gtccaccaga tagacaagat ccgtattgcc gctgaccatc
    16321 agcgtcccgt ccgcacccag gacttccgtc acggtatagc cgagggaagc caggagagga
    16381 gagaatccga tttgcttgaa attatccaca gccagggttc ccgttgtcag tacaagccct
    16441 acgccgtcag tggaatcccg gttggcggca agcaggtcca gaacaccctg gttgctgagg
    16501 ttgatggttg ttgtggcggc tgaaagcgtc aggctgtccg catcaataac gccctgtccg
    16561 gtagttccga ccgctgtaag gctgccggaa tccagtttca gcgtcaccgt cttgcccgtc
    16621 atgtccagag caccggaaac gcctgtaagc cgggagtaat cctccatgac gatggagccg
    16681 accatggagc cggacaggcc gcccagattg atggtattca gggctccctg cgttccggcg
    16741 gaagcggcca cttccacgtt tccagcggtt ttggcttccg cgtttgccag gcttcccttc
    16801 gtaatcagaa taacgttggc cgcatccagg gaggacagat tgagaacacc gttattgacg
    16861 gtgacccgtc cggaccccag ggagtcggcc cccgccaagg tgacggtgcc cgttccggag
    16921 agcgtcgtag aaccggtgaa cccggtgttg ccggccgcca gcgttatctc tccagcagtg
    16981 tcaataacca gggaaccagc tccggagagg gacccggccc agacacttcc gtcacccagc
    17041 cgcgccgtag cgccgcccgc aatggagagt gcgcccagga aggtgttcgc tccggtgagt
    17101 tccagcgttc cggcgtttac ggataccgtg ctgccggccg taccgctgat gacgcctccg
    17161 taggagaaat cgcgggcaaa ggccagcgtg gagttgttct ggatgtcaat gctgtccccc
    17221 agcttggcca catcggcgga attcacggta accgtgccgc ggtgcacctt gagctgaccg
    17281 tccaggttga cgccgcccgc cagggtaata ttgcccgctc cctgggtgga gaacgccgtt
    17341 ccgctcaaat cgccgctgaa gg
//
