LOCUS       gnlProkkaNECHEGGL_177  10956 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NECHEGGL_177.
ACCESSION   gnlProkkaNECHEGGL_177
VERSION     gnlProkkaNECHEGGL_177
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 00:11:55
            Original ID  :: gnl|Prokka|NECHEGGL_177
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10956
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10956
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6013:6364]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6014..6364
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10956
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10956
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..1544)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg177_1"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(1737..1961)
                     /locus_tag="ctg177_2"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             2632..2748
                     /locus_tag="ctg177_3"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             3023..4534
                     /locus_tag="ctg177_4"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             4607..5674
                     /locus_tag="ctg177_5"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVCLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             5711..5995
                     /locus_tag="ctg177_6"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(6014..6364)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg177_7"
                     /sec_met_domain="PqqD_RRE (E-value: 9e-12, bitscore: 34.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVVPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(6462..7850)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg177_8"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(8099..8494)
                     /locus_tag="ctg177_9"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(8501..9274)
                     /locus_tag="ctg177_10"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(9280..9807)
                     /locus_tag="ctg177_11"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(9794..10954)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 344.9; E-value:
                     1.2e-104)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg177_12"
                     /transl_table=11
                     /translation="MAIQVAPTDLSVLITGESGVGKESFPQIIHQYSRRKHGQYIAVNC
                     GAIPEGTIDSELFGHEKGAFTGAIGERKGYFGEADGGTIFLDEVGELPMSTQARLLRVL
                     ESGEFMKVGSSKVQKTDVRVVAATNVNLTQAIAEGRFREDLYYRLNTVPIQIPPLRERG
                     DDVLLLFRKFSADFAEKYRMPAIQLTEDAKKELLAYPWPGNVRQLKNITEQISIIETNR
                     EISAAILQNYLPAQNTQRLPALMGTRESKGFESEREILYSVLFDMRQEVAELKKMVHNL
                     MAERAGQVGQVGQMGTVVTTPVVTAHQPSVPAIIHTMQPTVCKDDDDIQDTEEYVEESP
                     LSLDEVEKEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEYELD"
ORIGIN
        1 tattctaccc cgtgcatcat cttctgtaat ttcttcgaga gaaggaacag aatcaacgaa
       61 gcaacaccgg acattacgac gaataccata aagaaatcat acatggtagc aatctgataa
      121 ccaaagattg acttcacttt tccggcttcc ggatagagtc cgctcaacat tcccgcaaat
      181 ttattggctg tggcagtaga cagataccag attcccatca tcagggaagc gaaacgcagc
      241 ggactcaatt tatttaccat tgaaagtccg ataggcgaca aagctatttc acccatggta
      301 tgaataaagt aaagtcctgt cagccaaatc atgctcactt tcactccggg aactgcatct
      361 ttcactccga aacagatgaa aagataacct aaagaaagga gtaacagacc aatcgcttgt
      421 ttggtaggag aagcaggttc catctttcgc ttgttcagga acccccatac acccggcatg
      481 atatatgcca ggacaactac aaacagtgga ttgaaggatt gaaaccatga agccggcatt
      541 tcccaaccga atatgtcacg attcgtctgt tcggatgcga agagagttaa agaagctccc
      601 gcctgttcgt aggctgccca gaagaagatg acaaagaagg ctactatata gataacgaaa
      661 atacggctgc gttctatttt tgtcaatgaa ccgtctaaca ggatcagaac agggaaaaca
      721 atgcaggcgg taaaaatgcc gatactcacc caatcgcctt caaatgcata gttaaagaag
      781 gctattaaag caatggtaag aattgtgatt acaagggtat tacgtacttt ggtacgtttg
      841 tccatcttcg ggtgtgagat atggtcggcc ttgtcttctt tcttttcacg tttagcatcg
      901 gggataatac caatcggttc tccggaagga gaaaaaagat atttattctt ttgagtctcg
      961 aaaagaacaa cggtgaacag tgtcatgatt ccggctgcaa gaaatcccca tttaaagtca
     1021 tgcggatcac cggtatcacc cagataacca caaatcaaag gagcagcaaa agagcctaca
     1081 ttcactccca tataaaaaat ggtgtatgca gcatccaacc gcctgtctcc gggttcgtag
     1141 agctgaccta ccagagaaga gacagtgggt ttgaagcaac cattgcctag aatcaggaag
     1201 ccgagtccac catacatcat ccagtgggca aggttcgtat tatctaaagt ggaggcactc
     1261 ataaacatca ggaattgtcc gactgccatc attaccgctc cccaaaacac ggaacgacgg
     1321 attccccaat atttatcggc aatgtatccg ccaatcaacg gggttaaata aactagtccg
     1381 gtatagctgc cgtagatgga tgctgccgct tctttgtcaa acaataatgc ctgcgtcagg
     1441 aaaagaataa agatcgcacg cataccgtag taactgaaac gttctgccgt gcttgtcgcg
     1501 aaaatcagat aaaggccttt cggatgccct ttcaatgcac tcatgaattt atgtgtttag
     1561 tagtttatgg ggtgcaaagg tacagaaaaa gtagattaga tgcttctctt atcaaacaga
     1621 ataatagggg gaatagtaaa aacgagcata aaaatcctac tgatccactt cattactttt
     1681 ttagcagtgt aaataataaa gtggagatcc atcttaaatg taggttagct accaccttag
     1741 ccaaaagtaa attcgacatt ttcgatactg gcaaaaagca ttccttctct tttcctcaaa
     1801 aagattttgt cttctcgggc cagccaacca atagcaagag ctacgtcttc aaacgtcaaa
     1861 cttaattcac ggcacaaatc gaacattgaa agttcacctt tttcatttaa gatgcgccat
     1921 actttcccgg cattcaagcc aatttttgtc ttttccatca tgcaaacttt agaagattaa
     1981 acaatccgtt atttagattt taattcattt tcattgtgag cactggaaaa taatgtgatg
     2041 cacattatct atctccaaag ataacatttt tatcggaaac ggcaaataat caaaggctta
     2101 atcaggggaa ccgcattaaa aatttgttta agaaggtatg gcgataaact aaacacaatt
     2161 tccatccgcg cctctacaga aaaagatttt tcatttctca tattctcata aataagaaac
     2221 aagtggcagt aaactaataa gatagactat gagaaatgat ttaaaaacag gcatttctca
     2281 tagtttcttc gcaaaataac ccggattttg cttcatttct catagtgtag tgtgccggaa
     2341 gctgacattg aataaataaa actatgtatt ccttttgctt gcttccatac acagtgtctt
     2401 agttccacat attgtgggaa tagattccct aaggcttggg aaagtattcc cttattttgt
     2461 gggaaagtat tcccgtatat tgaaggaaaa ctttcccaca atatatggga caatcgagac
     2521 caatgagcat cttcaagcaa aaagccacta ttttatctaa atagtagctt catttcctga
     2581 taaaaataag gcaggctgaa agaaaaaagg aagaacaaat ggcttttgac tatgagaaat
     2641 accctgaaat actatgagaa taaggtggct tttgagccaa aatatgggag aacttatgag
     2701 aaataccgtt tcgaaaaagt gtttctcata agatatctat ttgattagct ttcgtttatc
     2761 gaaaaacaat gagaatatga gaaatgaaat gaagaaatct ttttcaggag aaataaaagt
     2821 aagttcataa tggtgctgca ttgaattatt ttttggcgga gttattctaa cacttaatag
     2881 ttcaaaaaca gatatttctc tgacccaaag atagaactaa tgatgaatta aaagttgcaa
     2941 ttatggtttt cttcccacaa caaacgggaa aagtcagaag aatcatgtac atttgtaatc
     3001 cgaaaactaa aagaacatcg caatgaaaat atttccaagc agcagtatca agaaattgga
     3061 cgcttatacc attgagaacg aacctattgc atcaatcgat ctgatggaac gtgcagcaac
     3121 cgtattaaca aaagccatca cagacagatg gaatacggaa acgccggtca ctatctttgc
     3181 cggaccgggg aataatggcg gagacgctct cgccgtagcc cgcatgatgg ctgaaaaagg
     3241 atataaaatc gaggtatttc tcttcaacac gaaaggagaa ctttcacccg actgccagac
     3301 caataaagaa ctggtagaaa tgatggaaga agtaaaattc cacgaaatca gtacccaatt
     3361 cgtacctccc gtcctgacgc ccgatcacct agtaatcgac ggattattcg gttcaggcct
     3421 gaacaaaccg ttgagcggcg gattcgctgc cgtagtgaaa tacatcaatt cctcccctgc
     3481 catggtagta gccatcgaca ttccttccgg actgatggga gaagaaaaca cattcaacgt
     3541 aaaagctaat attatccgtg ccgacgtaac tttcagtctg caactgccga agctcgcctt
     3601 tcttttcgca gagaacacgg aatttgtcgg agaatgggaa ttgttggata tccaattgag
     3661 cgaagacggc attgaagaga tggaaacgaa ctacgaaatg ttggaaatag agcaaatccg
     3721 ttcactcatc aagccacgca aacagtttgc ccacaagggg aacttcggcc atgcactatt
     3781 gattgccggt tcaaaaggaa tggcaggagc ctctgttctc gctgcccgcg cctgcctccg
     3841 ttcgggagta gggttactga ctgttcatgc accaatgtgc aacaacgaca tcttgcagac
     3901 ctccataccc gaagcaatcg tagaaaccga tatcaacgaa acctgttttg ccgtacctac
     3961 cgatacggac gactatcaag cagtcggcat cggcccaggg ctgggacgaa acgaggaaac
     4021 ggaagctgcc ttgttggaac aactggaaca ctgccagact cctgttgtag tggatgccga
     4081 cgcacttaat atcctcgcca accaccgtca tgcacttacc cacctaccga agggttccat
     4141 cctcaccccg catccgaaag aactggaacg tctgaccggc aaatgccagg actcttacga
     4201 acgtctgatg aaggcttgcg aactggcccg tgccgcccat gttcacatta ttttaaaagg
     4261 agcctactcc gccattatca cccccgaagg taaatgtttc ttcaacccaa ccggaaatcc
     4321 gggaatggca accggaggta gcggtgacgt actgaccgga gtaatcctgg cgctgcttgc
     4381 ccaaggttac cccaccgagg aagccgctaa aatcggcact tacattcacg gattggcggg
     4441 cgatgtcgct caaaagaagc aaggaatgat cggaatgatc gcaagcgata ttatcacctg
     4501 tctgccgaca gcatggcgac ttgtaagcga ataaaagtta agaacttaca gttttttcaa
     4561 taacttcatt aactttgttt tcaaaaccag ttaaaaagaa ccgaatatga aaaagttgat
     4621 tatagcagca ggactactta tgacaacgtc cgcctatgca caaaccgaag tactgacggg
     4681 ggttacccga ggaaaagact atggagtggt ttacagtctt cccaaaaccc aaatagaact
     4741 tgaaataaaa gccaacaaag tcaactatac tcccggagaa ttcagcaaat atgctgatcg
     4801 ttacctgcga ctgaccaacg tctccgccga tcctgaagag tactgggaac tggctagcgt
     4861 aaaagtgaaa tccgtaggtg tgcccaacag cgaaactacg tatttcgtaa aattgaagga
     4921 taagacagta gcaccgctca tggaactgac agaggatggc attgtgaaaa cgatcaatgt
     4981 tccttacagc aacagcagtg taagcaaaaa agttgctccc gctcccgcag tcctccaaaa
     5041 gaaagcgaat cctcgcgaat tcctgaccga agagattctg atggctagtt ctaccgccaa
     5101 gatggccgag ctggtggcta aagagatcta taacatccgc gaaagcaaaa atgccttatt
     5161 gcgcggacaa gctgataata tgccttcaga tggggcacag cttaaaatta tgctcgacaa
     5221 tctgaatgca caggaagaag ccatgacaca aatgttctcc ggcacctgca acaaagaaga
     5281 gagaacattc actgtctgcc ttacccctga caaggaattc aacaatgaag ttgccttccg
     5341 cttctcgaag aagttaggtg tagttgccaa caatgatttg gcaggaactc cgttttatat
     5401 cagtctgaaa gacctgaaat cggtcaagat accacaagaa gacggtaaga agaagaaaga
     5461 tttggatgga atcgcctaca acgtacccgg acaagctatg gttacactga ccgacggtaa
     5521 aaagaaactt tacgaaggtg agcttcctat tacccaattc ggtgtgatag aatatctggc
     5581 tccggttttg ttcaacaaga attctaccat caaagtttat tttgatccga atacgggagg
     5641 attgctcaaa gtggacagag aagaagggaa atagaaaaac gaggaagtga acttctaaaa
     5701 aacaaagaat atggttggtg aaggacatgc attcgacatg atacgccgaa taaaagaggg
     5761 acgggaagct tcccgcctac gtcgtgaacg tgctaacgat aagttgaagc atctaaaccg
     5821 tgcaaacgaa ccttatccac tacccaacac cacccccgaa gaaatggaac gtatcatcca
     5881 cgactcggag aaaaagaaag agaaagacag caattatttt gtttggggaa cgcttattat
     5941 catgggggtc ctgatagcaa ttgccgtcat actttgggct gtatttatca aataaataat
     6001 aataagttcc tatttatacg actggtatca ccagttttat aaatccatct ttctgcattt
     6061 gagaaagata agccgataca cgcgactcgt agccctcttc attttgaaag tggtctgcga
     6121 gtttttctat aatctcacga acattgcgtt ttccatctat cagttcccat acagccgtac
     6181 cgtgttcttc caatttcaca tgaagttctt tcgacattcc tttcggcaca aggaagcgtt
     6241 gcatccacgg atatttaaaa cggggaaagg agagcacaat tgtctcccct tccctttctg
     6301 ctgtaatatg ttcactgcga cagggaacga cctctaacag gttgattttc tctttggcag
     6361 ccatacttct tattttttat ttcagagtat tcatactgat acccttttgt ttacaccttg
     6421 atacaaaatt cctttgttac tttaggtatt gaatttccca gttacttttg gatattcgcc
     6481 tcttccagac cgtatccctt cttcttgttc tctgccttca acatcaaagc cacaatcaga
     6541 gcaagcacac caaaaagagc aaaaatagtc atcggcaacg tgtagtcata agtctgtgca
     6601 ccgtctacta ccggaccttt gcaataagta ttcaacaccc atccgatcaa caaaggaaca
     6661 cccatcaatc cccagttctg tacccagaaa atcaatgcgt atgctgtacc caactgtttt
     6721 tccggaataa tcttcggaac agacggccac atagctgaag gcactaacga gaaggcaaat
     6781 cccaatataa tcatgataat agtagcaaac caccatatat tcagtatagg cagagcgaac
     6841 atcgtatgca caaaaataag catcactgat ccgattatca tcaacgtagc tcccttaccg
     6901 atacggtcat aaagcgagcc gaacaacgga gtcagaataa tcgcaccaat cggcaacaat
     6961 ccgggaatcg ttcccgccaa cttcggatcc acattatact tctgcaccat caagtcggca
     7021 gcatacttga taaaggggaa tacagccgag tagaacaata cacatagtaa tgcaatcagc
     7081 cagaatcctt tattggtaat gatatacaca atatctttca tacggaacgg ctcttccggt
     7141 tccaatccct ctgcatccaa agaagcatcc aacttcttat catagaaagt ataaaggaag
     7201 aaagcaatcg tacccacgca caacataatc agacaaaaca aaatcggagc aggaatattg
     7261 gtatggaatg tgccactctc atccgtagat ccgaaaaagt cggccaaagg aaccgtgagc
     7321 accattgcca gagttgttcc gatacgtgcc gtagccattt caagtcccat agccaatgcc
     7381 atttccttac ccttgaacca tttcacgata attttggaaa ctgtgatacc ggcaatttcc
     7441 acacctacac cgaagatagc ataccccaat gcagccaggg ttacctgtgt tttgaatccg
     7501 aagagcatgg caccttccgg aaaagtagta gaaatcgcat agtatttcaa tccacaacca
     7561 aacaccatca ataagcaagc tcccattccg gtgaaacgaa ctcccatctt atccaaaatg
     7621 ataccaccga aaatcagcat caataggaat acattaaacc acccgtaagc gcttgtgaag
     7681 aaaccataat caagactgtc ccatagtagt tctttctcaa gcatgggttt tagaggagac
     7741 attacgtcgg tgaggaaata gccgcatagc atagtaaatg cgaccaatgc tagaacactc
     7801 catcggagta cggcggagtc attcaatttc tgtttcaaat gttctgtcat tgttatattt
     7861 aaaaaagtag ttaataatct tcatacgacc aacaaaggta gttaaatctc gtttgtttct
     7921 atcaaaaaga gattgttttt acaagaaaaa gttaagtgcg gattacactg accacgcgga
     7981 agattgaaaa tccgtgtaat ctgcgtaatc cgcacttaaa tatcaaagaa atgcagcatc
     8041 cgtctgcacc ttcccattaa tggttttacc ccaaagtctt acctgacaac ggagtgaatt
     8101 actctgctgc aggagcagga gtttcagtag ccggtgccgg agtttctgta gcaggtgcat
     8161 tggtagcagg agcttcagtt tgcggcgcag ccgtacctgc gggtaagtta tacgggttag
     8221 tctgttgttc tttctgtgcc tgttccaaca ctgcgtcttt agcaacagca gagcgaggaa
     8281 ctacataagc agtagcaatg ctcattacca ccatgaagat agctaagccc catgttgctt
     8341 tttccagaaa atctgtagtc ttgcgcacgc ccatgatggc gttagatgaa gagaaaccag
     8401 aagcaagtcc gcctcctttt gagttctgaa tcagcacgat gaaacacatc aacaaggctg
     8461 caataaccat taagataacg aataataagt acatttttag ttattttgaa ttagcgttaa
     8521 taatcaattt ctccaaaaat ctgatttggt ctgcaaagta agcatttttt tttggatatt
     8581 tcaagcttaa ttttttaatt atttcaagag cttttgaata tcgttgctgt ttaacataga
     8641 tttttgccaa agtttccgta aaacagctgt catcttcctc ttcttccttc atcgtttctt
     8701 cttcggtaag ttcgtccgaa gaggttggcg aagatggcat ttcttctctt aaaggtttca
     8761 tgcagagggg agagtcgctc tcgctctttt ctataaagtc gtcaatcagt tcgaagcctt
     8821 tgagtttggg cgtttcttcg gccggctgtt ccgtggccgg agtctcctcc aaaagataag
     8881 aggtataatc catcgaatag tcgaagctgg tgcgggcagt cacctcttcg ggtactgtgg
     8941 acaagaaagc gtcgatcaat gctaatgtgc ggtctacgga cggttcgtct ttcagtacct
     9001 ccgtgagagg tactcccttt ttccgtgctt gcacatcata gcggtcacct tcaatcaacc
     9061 ggaacaactg ccgtctgtct gcaatgtaaa gaactgcttt ccgcagttct ccaccgaaac
     9121 taatatcatg gagaatatac agattcttca gatacagcag acgaagtgac tgaaaatacg
     9181 gatacctcgc aagaagattg cgcagttcgt acaaagtatc cctattcagc gtctcgggat
     9241 gctgaatcca ttgttgaaag ttaacagaag tcatttatat taccagtttg ctacagttgc
     9301 attaaaaatt tggtcggtga tctctttaga catttcagca atcaatccgt cctgtacggc
     9361 agtcagcaac tggctagagt cgtaggtacg gaacgcagaa aactgttgtt caaagtcttc
     9421 ggcatgattg gtgttgttga caaaacgtac attgacggtg atagtcaact tcgtctccga
     9481 agaataaccg tcggcagata cagcctgatt gtactgattg taacctgtga tttctccgtc
     9541 aatctgcaag tcggcatttt gactcggctt gagcagttgc agacgggtct gccggatgaa
     9601 gatatctttc aggtcctcat taaacttggt tgccaacgga gcatacacat actccgactt
     9661 gatcgggaag tcggctatcg aaatggtctt taccttatca taattgatag acgatccgtt
     9721 aaacttatag gaaacagtgc acgcaatgac taccaacggc aagccgaaca gtaacaaagg
     9781 gcgtattatt ttcttaatcc aattcatatt cttttatttt tctataaagt gtacgctcgg
     9841 aaatattcaa gtccttggcc gcactcttcc gctttccatg atgcctctca agtgccttgc
     9901 gtatcatttc tttctccact tcgtccagtg acaaaggaga ttcttctaca tattcttccg
     9961 tgtcttgtat gtcatcatca tccttgcaaa ccgtaggctg catggtgtga ataatagcag
    10021 gtaccgaagg ttgatgcgcc gtcactaccg gagtagtaac caccgttccc atttgtccta
    10081 cctgccccac ctgtccggca cgttccgcca tcaggttgtg caccatcttc ttcagctccg
    10141 ccacttcctg gcgcatatcg aacagaacgg aataaagaat ctcccgttcg ctctcaaagc
    10201 ctttactctc acgcgttccc atcaacgcgg gaagacgttg cgtattttgt gcgggaagat
    10261 aattctgcaa gatagcagca gagatctccc tattggtttc aatgatagat atttgctcgg
    10321 tgatgttctt caactgacgc acgtttccgg gccacgggta agccaacaac tctttcttcg
    10381 catcctccgt caactgaata gcaggcatcc ggtatttctc tgcaaagtct gcggaaaact
    10441 tacggaacaa caaaagtaca tcgtcaccac gttcacgcaa aggcggtatt tggataggca
    10501 ccgtattcaa ccggtaatat aaatcttcac ggaaacgtcc ttctgcaatc gcttgtgtca
    10561 gattgacatt ggtagccgcc accacacgca catccgtttt ttgtactttg gacgaaccta
    10621 ctttcataaa ctcgccactc tccagtacac ggagcaaacg tgcctgggta gacatcggca
    10681 actcccctac ttcatcaaga aaaatagtac caccgtcagc ttcgccaaag taccctttcc
    10741 gttcgccaat cgcaccggta aacgcaccct tctcatgccc gaacagttcg gaatcaatcg
    10801 tgccctccgg aatagcacca cagttgacag caatatactg tccgtgcttc ctccggctat
    10861 attgatgaat aatctgcgga aaactttctt ttccgactcc actttctccg gtaatcagca
    10921 cagacaaatc ggtaggagct acctgaatgg caacat
//
