LOCUS       c00112_gnlPro..        15032 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NECHEGGL_112.
ACCESSION   c00112_gnlPro..
VERSION     c00112_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:09:36
            Original ID  :: gnl|Prokka|NECHEGGL_112
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15032
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15032
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7374:12592]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7375..12592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15032
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15032
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..137
                     /locus_tag="ctg112_1"
                     /transl_table=11
                     /translation="LCPDTVIAHWLYLVGVSAVLAVAYILFMKKNYHLHEEYLISLKQ"
     CDS             143..580
                     /locus_tag="ctg112_2"
                     /transl_table=11
                     /translation="MEFDKEFLDKLFEQAMENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGKLDEVIYEEVVSYEKDTDDFQKGVNVQDVARKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(855..1277)
                     /locus_tag="ctg112_3"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRGRALEKIGAHCRNHNAHSVGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALVVGHRDLNPMKGCPCFDAVKEYAEITSF"
     CDS             complement(1282..1389)
                     /locus_tag="ctg112_4"
                     /transl_table=11
                     /translation="MSKSSSPRSVWSLVLKIVITVATAIGGVFGIQSCM"
     CDS             complement(1577..2065)
                     /locus_tag="ctg112_5"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             2285..2503
                     /locus_tag="ctg112_6"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             complement(2685..4526)
                     /locus_tag="ctg112_7"
                     /transl_table=11
                     /translation="MTDIESLCRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPPHTGAYNKVGNDNISEEREGEEELLPGSEPQHQLPTFPENDWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVAIQMKAYKKEKTEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKTHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGREMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPADNRKDDIITRWDVSISQ
                     EDFHAVLSLAEPLYCHATHILSFLPNTEISHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKHGKLISMDGKGLYARACVYE"
     CDS             complement(4565..5188)
                     /locus_tag="ctg112_8"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFTRRSCKDFVSPSHLVIVDVDGLH
                     SYQEAVEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCHYSSTTNDTKNITENMSWAMR
                     YVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTK"
     CDS             5355..5507
                     /locus_tag="ctg112_9"
                     /transl_table=11
                     /translation="MENEKGLYVALGVYIGELQKRADLKNDEIRKSVHIGHSTFNDLKK
                     GQNAH"
     CDS             5788..6657
                     /locus_tag="ctg112_10"
                     /transl_table=11
                     /translation="MSSKIYPIGIQNFEKIRKDGYFYIDKTALIYQMVKTGSYYFLSRP
                     RRFGKSLLISTLEAYFLGKKELFEGLAMEKLEKDWTTYPIFHIDLNTEKYDTRESLDSI
                     LNFTLEKWEQQYGTAPSETTFALRFRGLIERAYEQTGQRVVILIDEYDKPMLQAIGNEE
                     LQKEFRNTMKAFYSVLKTMDGCIQFAFLTGVTKFGKVSVFSDLNNLDDISMRKQYVDIC
                     GVSEKELHDNLEIELHELADANELTYGELCNRLREYYDGYHFTYNSIIKFLLPFYANTN
                     AVESEFEI"
     CDS             6802..6945
                     /locus_tag="ctg112_11"
                     /transl_table=11
                     /translation="MVAISFPCAITKTQKITIYYVEKVGGMLRSSQIMIKFAAICNAEF
                     AK"
     CDS             6942..7367
                     /locus_tag="ctg112_12"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMAWIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             7375..8289
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.9; E-value:
                     3.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_13"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-12, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.8e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 9.9e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.7e-08, bitscore: 25.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4.2e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-06, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCANRPRTNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNSIIELNFPPRKPKEEAPA
                     APKPATKVETPAAKATEAPKVTE"
     CDS             8314..9651
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_14"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.2e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.6e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-29, bitscore: 92.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSTTLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             9657..10664
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_15"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-120,
                     bitscore: 392.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIHAADKSAAMDALNQIPDALSLLIGQNGGCLGEVSALALLIGLVYMLWKKIIT
                     WHIPVSILATVFIFAGIMHLADPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGM
                     LIYGVCIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             10691..11398
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_16"
                     /sec_met_domain="FMN_bind (E-value: 2.6e-23, bitscore:
                     73.0, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKGEQAVSHEESKKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGKVNGVSGASQKATGADSDTATGA
                     TIKVELTDSVSAK"
     CDS             11413..11997
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_17"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.9e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             12020..12592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_18"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.5e-63, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             12816..13850
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_19"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 3.4e-52, bitscore:
                     168.3, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGLREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             13897..13986
                     /locus_tag="ctg112_20"
                     /transl_table=11
                     /translation="MRFVYLMLIDLKLFMSMRIYVNGTYASPA"
     CDS             complement(14107..14931)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_21"
                     /sec_met_domain="GHMP_kinases_C (E-value: 4.2e-10,
                     bitscore: 30.5, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.5e-10,
                     bitscore: 31.8, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSS
                     ETEKKITLHQYGMEIAGNPEDNLVAKAYSLLDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHFQLELSEEQLEVYAATLGADCAFFIKNKPTYAEGIGNLFSPIELSLS
                     GYQIMIVKPNVFVSTREAFSNIHPHRPEYPVKEAILRPVAEWKDILINDFEASVFPQHP
                     VIGEIKRELYHQGAIYASMSGSGSSVFGLFAPGTSLPETMGESDVFYFKGKL"
ORIGIN
        1 atctttgtcc cgatacagtg attgctcatt ggttatatct ggtgggtgta tcagctgtat
       61 tggctgttgc ttacatatta ttcatgaaaa aaaactatca tttacatgaa gaatatctta
      121 tatcattgaa acaataacga ttatggaatt tgataaagaa tttttagata agttatttga
      181 gcaagctatg gagaatccac gtttgcgtca gaacttcgac ctacgcactt catctgccga
      241 taccagtcaa cgtatgctaa acgcattgtt gccagaaact aaggtgccta tccatcgaca
      301 tgaagatact accgaaacag taatctgcct gtgtggtaag ttggacgaag taatttatga
      361 ggaagtagtt tcgtatgaga aggatacgga tgattttcag aagggggtaa atgtacaaga
      421 tgtagctcgt aaggttgagt atcgagaagt acagcgtatc catctcaatc ctacagaaac
      481 caagtatggt tgtcagatac ctaagggtgc atggcatact gtggaagtga ttgaaccatc
      541 tgtcatcttt gaggctaaag atggagctta tgctcgttaa acgatgaaaa acagatgaaa
      601 tgaataggaa gtactgaaag tgctttttaa tacgttatgt tataattgaa catttataat
      661 gagatggaaa aatgtaggtc cctagattca tgtgacaaac atgaatccct acatttagta
      721 gattaggagc aatatagtga tattgtccta atctcgctct tcatattagt gttagcacta
      781 atatgatttc caaaaatacc aactgtctgt gaagatcgtt gatatttttt atacaataag
      841 ccagtggtgg aaacctaaaa ggatgttatt tctgcatact ctttcaccgc atcaaagcac
      901 ggacatcctt tcatcggatt taagtcccgg tgtcccacga ctagtgcttt cggaaactgc
      961 cttttcaact ccctcaacaa agcaagcaaa gctccttttt gttccagtgt acgcgtatct
     1021 ttcggttttc cgttcgcatc cagtcctccc tcataacaaa caccaaccga atgggcatta
     1081 tgattacggc agtgtgctcc aatcttttct aaagcgcgtc cccggtgaat ctccccatca
     1141 cgagtgatgt agaaatgata gccaatatca cggaaaccac ggtgcaagat atgatcctgt
     1201 cggcaagcct ccgccgaaag ggactttcct tccggcgtgg cactgcaatg aatgataatt
     1261 aatgtaatag tccgcatggg gttacatgca actttgtatt ccgaacacac ctccgatggc
     1321 ggtggctaca gtgataacga ttttgaggac taagctccat acagagcggg gagatgatga
     1381 tttactcata caataacagg ttttaaataa attaataata gttttctttt accacagatt
     1441 taccacagat ttactgtagg tttaccatag gtttaccaca gatctacaca gactcacaca
     1501 gataaataat cgactacttt agcaactacc aattcaatat aatctgtgga aatctgtgta
     1561 gtcagtggtg aatcttttag gcagccgggt caggcgcttc accacctcca tccggtttcg
     1621 gatcagggtt gtcacccgaa tcagaacctc ctccggcagt tgtcggtttc tgatattccg
     1681 cctgctgctt caactggcta tcgagtttca gattattggt cgacagatta ccggtggcac
     1741 gggctttcag acgcatgccg ctaatattct tctccaacga gaactcttcc agcgtatcgg
     1801 ctgccttact gcgaataccc acaccaaaaa tggcaagatc atcaattttc acacacttgc
     1861 cgtctagcaa caattctttg atgcaatcta ccatatccga aagcacacct ttgatgacac
     1921 caccggaata cggtgaattg tgcttcgaca tatgttcggc aagctttgcc aaatcaaacg
     1981 tctcgtcgct tactgcacgg gcgaaccact tacccgcatt caagcctttc ttctgctggt
     2041 tctgataaat tttgtaacga atcataaaac aataaattaa agggttaaac atattgtccg
     2101 gggattcttt tccctttcga cgatacaaaa atactactcc ggatctcccg gaaatcagct
     2161 gtgcacggtt gtgtctggta gcggtcggtt atttgtcatt atagtcggtt attcaatgga
     2221 aaaacgttgg ttatatagtc gttttttgtt atttttgtaa cagtaaatca gaaatatatc
     2281 catcatgagt gaatttaaaa tacgtgctta cgggcgcatg gaactggcgc aactctattc
     2341 tccacaacta actgacatcg ctgcctatcg aaaaatgaag aaatggatct ctttgtgtcc
     2401 cggacttctg caacgcctgt acgacttagg ctacgaatca aagcgacgct cattcacacc
     2461 gttggaggtg agagttattg tggatgcttt aggagagcct taaataaagc gtcgctttat
     2521 ggtgtataaa gcaccgcttt acgatgtcta aagcttagct ttacacctcc taaagcgatg
     2581 ctttatgcag gacaaacgat tgtttcagtc aaaacggatg tggtaattga aatgactact
     2641 gcatccgtaa ataaaacggg tacagtaggt acactttttc cggttcactc atacacacac
     2701 gcacgcgcat acaacccttt accgtccata ctgattaatt ttccgtgttt ggtgagacgc
     2761 ttcagccaag tgagggctgt gttttcctta attcccatgg caactgcttc ttccagtaac
     2821 tgtgtacgag taaattcatc acccagtttc tggaagagat aatcacgatc ggcattagga
     2881 cggtggctga tttctgtatt ggggaggaac gatagaatat gcgtggcatg acagtagaga
     2941 ggttccgcaa gactaagcac agcatgaaag tcttcctgtg aaatggatac atcccaacga
     3001 gtgatgatgt catctttgcg gttgtccgca ggaatctcct tgtccggtgt gaaaggagag
     3061 gtgggagagg tcttgaagtc gtagggctgc gggctttcga gggcacgcaa tacggctact
     3121 tccgacatga ttctgcatag attgacggcc agacgtgcca caaaactata catttccctt
     3181 ccattagcta cactggagcg ttcaaacaag tcggaaaaga cggtgtcgat ttcttctttt
     3241 tgttcatccg tgagttgcag ggtatgaatg ccgtgagttt ttatcacgct caacttttct
     3301 ttccattcca gtcccatagc ggtgaatatc tcctcccaat ctatctcgtt gtccataaat
     3361 tggctgatcc atttactgat tccgcacatg taataatata attggcggga gtatgatccg
     3421 tcttctgccg tcggaatgaa agtttgcacc tgcgacggcg tacccgaaat cagaacggaa
     3481 agatagcttt tcttcacttc ccggtattcc tggtcggtgc ggcggttgta ggacaagcgg
     3541 tcgtggtcga acgctttgcg cagggtatcg ctccaatgac cgtggtccga tccgatggcg
     3601 gtggaaaggg tgtccgcttc cgcttcgcag ataagtccgg ttccgtcgga gtccatgatg
     3661 ttttgtagga tacccgtacc ggtgttgttg cccgaaatga ggaacatcct gttagggggc
     3721 atttgtggag cctccttttt ggttcgttct tttcccattg catcgtactc ggttttctct
     3781 tttttgtatg ctttcatctg tatggccact tctttgcgga tctcgtcgtg gataggttcc
     3841 acgagtaagc ggatgtagga aaggatacct ttgccggagg ccgaaggagc cactacgaaa
     3901 cattggaggc tggggtgatg gtatttgccg ccatataggc atcgcacgtg gcgcgacata
     3961 caagcaccca gggcagtgag cgctcccaat aacatgatgt cgtgttgtat tgggctgctc
     4021 ccggctttta tgatacgttg caaaaattcc ggccagtcgt tttccggaaa agtgggcaat
     4081 tgatgttgcg gttcactgcc cggcaatagt tcttcttccc cttctctttc ttcggagata
     4141 ttgtcattcc ctaccttatt atacgcgccc gtgtgtgggg gaaatttgcg tgctgtacct
     4201 gctgtacctt ttgtacctgt gggatgtttg ggcatttctt ctatgcagat gcttactccc
     4261 gtcgcttcgg ccaggtggaa agcggtgccc aagtgcactt ctccacgttg ggtgtggagt
     4321 gcattggaga atacccgttc ggcatgttcg cgctgatact tgggagacac ccggcacagg
     4381 cgatggaaaa agtcacgtcc tgcttcaccg caatccgttg cgatggcgaa tgacaattgt
     4441 acgtattcaa gataggtggg agcaatgtcc gctcctgccg cttcgactgc ttcggtgaga
     4501 cggcataaag attcaatatc ggtcatgttt tgatttttat aaaataatgt ttaattattc
     4561 tcgtttactt ggttctgaac aatgcttccg ggtcgtaact aaggaaacag gatctcacga
     4621 ggtctttgcc ggagaaatct actttggatt tcgtttcgga agaaaccgct gttaccgtat
     4681 tgtatgccgt ctctacgtac cgcatcgccc aactcatgtt ttctgtgata ttttttgtat
     4741 catttgtcgt ggaggaataa tggcaaggaa caaatgcctt tacacccagt ccgctggggc
     4801 tgataaaggt gagtacaggt tgtaggagag ggtcgtcata gagcatacgt cgcatttcta
     4861 ctgcttcctg ataagagtgg agaccgtcca catctactat caccagatga gacggggaga
     4921 cgaaatcctt acagctacgg cgggtgaatg tgccgcaagg ggtcacatag ggaagcaatg
     4981 atgctttggc ggctcgtata tctgtggcat tccgtacttg tgcggtcagg gttttgagat
     5041 tctcattgca agtaatcatt tggaaaactt gttcgatgga gacttcgcag aaggggataa
     5101 gcgtgggagg agtcatcagt cggccttgtt tgtctttgat gggagcgata ggtggcataa
     5161 aataggacat tctgtagttg tttgacatca ttttcttttt gttataagtt aaaatgttta
     5221 tttttgcaaa aaatatgagt gtgtttcaaa acacggcgta aaattagtaa atgcaaaata
     5281 gacatcgtcc cgacatgttg ggatgaaagt gaaaataatt aaccgttacg gtgtaatttt
     5341 aacaataaaa aagaatggaa aatgaaaaag gtttatatgt agctttagga gtttacatag
     5401 gagagttgca aaagcgtgcg gatttgaaaa atgacgaaat acggaagagc gtacacatcg
     5461 gccactctac ttttaatgat ttaaaaaagg ggcaaaacgc ccattgagtg attacgtaaa
     5521 agtggtggag tgctgtctgg atgccttcaa tgaagaggaa gccggagtta tctgggatga
     5581 atggaggaga atgtattttc gatacaggag aagaaaagag gaggagagag gagaacggtg
     5641 aaaaaacaga taaggtaaaa gcggcaggcg ggaaaaagtt tcccgcctgc ggtctttatg
     5701 aatggatttt ttttgtagct ttgtgaaaaa taagattgat atggaagatt tgtctggtaa
     5761 tttttataat ttaagaaaaa gaagcgtatg agtagcaaga tataccccat tggcatacag
     5821 aactttgaaa aaatccggaa agacggttat ttctatattg ataagactgc tttgatttat
     5881 cagatggtga agacaggcag ttattatttc ttgagccgtc cccgtcgttt tggaaaaagt
     5941 ctgttgatat ctacgcttga agcgtatttc ttgggcaaga aagaactttt tgagggcttg
     6001 gccatggaaa agctggaaaa ggattggact acatatccca tttttcatat cgatcttaat
     6061 acggagaagt atgatacgcg ggagagcctg gacagcatat tgaatttcac attggagaaa
     6121 tgggaacagc aatatggcac cgccccgtcg gaaacaactt ttgcattgcg ttttcgcggc
     6181 cttattgaac gggcttatga gcaaaccggg cagcgtgtgg tcattctgat agatgaatat
     6241 gataagccca tgttacaagc aataggtaac gaggagcttc agaaggaatt ccgtaatacc
     6301 atgaaagctt tttatagtgt gctgaagact atggacggtt gcattcagtt tgcttttctg
     6361 acgggagtga cgaaattcgg taaggtaagc gtgttcagcg atttaaataa tctcgatgac
     6421 atctcaatgc ggaagcaata cgtggatatt tgcggagttt ctgaaaaaga attgcatgat
     6481 aatttggaaa ttgaactgca tgaactggcg gatgcaaatg agctgactta tggtgaactg
     6541 tgcaatagat tgagggagta ctatgatggc tatcatttta catacaattc tatcattaaa
     6601 tttttgcttc ccttttatgc gaacaccaat gcggtagagt cggagtttga aatatagaac
     6661 tttaacgcga aaatgcgtaa tattgagaaa tggatagtgg agtaatctgt gaaataattg
     6721 atggaaaatc ccggctgaag aaataaaacg gctgggattt tttgtttagg atgtctattt
     6781 gccattcttg aaaaatatca aatggtagct atatcttttc cgtgtgcgat aacgaaaacg
     6841 caaaaaataa caatttatta tgtagaaaaa gttgggggaa tgcttcgtag ttcacaaata
     6901 atgattaaat ttgccgcgat ttgtaatgcg gagtttgcaa aatgacgaat aatactataa
     6961 agcatctagg tattgtggaa aacatccaag gttctcatct gtcggtgagg attgtccaga
     7021 catcggcttg cgcggcttgt agcgcaaagg ggcattgttc ctcggcggat agtaaggaca
     7081 aaatcataga tattatagat accgcggctt cttcctatca ggtgggagag aaggtgatgg
     7141 tggtcggcga aacgtcgatg ggcatgatgg cagtggtatt ggctttcgta cttcctttcg
     7201 tacttcttat attttcattg tttcttttga tggcgtggat agagaatgag ttgtatgcag
     7261 cacttctttc tctggctgtc cttatacctt attatttcgt tttgtggctc aataaaacgc
     7321 gactcaaaca acaattttca tttactataa aaccaataaa taactaaaaa cattatgaat
     7381 ttgattctga ttgcagtgat ttcattggga gctatagcgc tcgtgctggc cgctattctt
     7441 tatgtggctt ccaagaaatt tgccgtgtat gaagacccgc ggattgctca ggtgggagaa
     7501 gtgcttcccc aggctaattg tggtggatgt ggctatcccg gttgtagcgg atttgccgac
     7561 gcttgcgtca aagccggttc gctggatggt aaattctgcc ccgtaggtgg acaacctgtc
     7621 atggcacaaa ttgctgatat cctcggactt gcagccggtg aagctgaacc gatggtagca
     7681 gtggtaagat gtaacggaac gtgtgccaat cgtccgcgta ccaaccaata tgatggtgcg
     7741 aagagttgtg ctattgccgc ttcgctgtat ggtggggaaa cgggatgtag ttacggatgt
     7801 ctggggtgtg gtgactgtgt ggctgcttgt cagttcgatg ccatccacat gaatcctgaa
     7861 acggggcttc cggaagtgga tgaagcgaaa tgtaccgctt gtggcgcctg tgtgaaggct
     7921 tgcccgaaag cgatcatcga aatccgtccg caaggaaaga agtcacgccg cgtgtatatc
     7981 tcttgtgtga ataaagacaa gggagctgtg gcacgtaagg cttgtacagt gagctgtatc
     8041 ggctgtggca agtgtgtgaa gacttgtccg ttcgaggcta ttacgctgga aaacaatttg
     8101 gcttacatcg atccgaacaa gtgtaaatct tgccggaaat gtgtggaagt ttgtccgcag
     8161 aatagcatta tcgagttgaa tttcccgccg cggaaaccga aagaagaagc tccggctgct
     8221 ccgaaaccgg ctacaaaagt ggaaactcct gctgcaaagg ctacagaagc tccgaaagta
     8281 acagaataat aacagaaaaa aatacagaac tgtatgttaa agacattttc aattggtgga
     8341 gttcatccac acgaaaataa attgtcggca catcaaccta ttatcacagc ggaagttcct
     8401 gcaaaggctg ttattttgct ggggcagcat atcggtgcgc ctgcaaaacc ggttgtagcg
     8461 aaaggggatg tggtaaaggt aggcacacgg attgccgaac ctgccggctt tgtttcggca
     8521 gcaattcact cttcggtcag tggtaaagtg gcgaagattg ataccatagt cgatgccagc
     8581 ggttatgcga aacctgccat cttcattgat gtggaaggcg acgaatggga agaaacaatc
     8641 gaccgtagca ccacactggt gaaagagtgt gaactttccg cagaagagat cgtgaagaag
     8701 attgccgatg ccggaatcgt aggtctgggc ggtgcttgtt tccctacgca ggtgaaactt
     8761 tgtcctcctc cttctttcaa ggctgaatgt gtgattatca atgccgtaga gtgtgaacct
     8821 tatctgactg ccgaccatca gctgatgctg gaacacgcgg aagaaattat ggtaggtgtt
     8881 tccatcctga tgaaagcggt gaaagtgaac aaggcattta tcggaatcga aaataataag
     8941 cctgatgcta tcgaactgat gaccaaagtg gcttccagct atgcaggtat cgaagtagtg
     9001 cccttgaagg tgaaatatcc gcaaggaggt gaaaagcagc tgatcgacgc gatcaccaaa
     9061 cgtcaagtgg cgagcggtgc attgcctatc tctacgggag cagtcgtgca gaacgtggga
     9121 acagcatttg ccgtttatga agctgtacag aaaaataagc cgttgttcga acgtgtgatt
     9181 accgtgacag gaaagtcggt tgcgaaacct tccaacttcc tggctcgtat cggtacaccg
     9241 atgaaacagt tgattgacgc ttgcggtggt ctgcccgaag atacgggtaa ggtgatcggt
     9301 ggcggtccga tgatgggtaa ggcgctcgta aatatcgagg ttcctactgc gaagggcagt
     9361 tccggtatcc tgattatgaa tcagaaggaa gccaaacgtg gtgaggcgca gacttgtatc
     9421 cgttgcgcga agtgcgtgag tgcctgtccg atgggactgg aaccgtactt gctcggagct
     9481 ttgtccgaaa acggagattt tgaaacaatg gaaaaagaaa gaatcatgga ttgtatcgag
     9541 tgcggctctt gccagttcac ttgtcctgcc aaccgtccgt tgctcgacta ctgtcgtctg
     9601 ggcaaaggca aagtaggcgc tatgattcgt gcacgtcaag ctaaaaaata acgaatatgg
     9661 aaaataaatt aatcgtatca ctatcacccc acgttcatgg cggagacagc gtacagaaaa
     9721 atatgtatgg cgtgctgatc gcactgattc cggcttttct ggtgtctctc tatttcttcg
     9781 gactgggtgc cctgattgtc acggctactt ccgttgcagc ttgtttgttc ttcgaatggg
     9841 cgatcgggaa atatttaatg aagaaaccta ccaccaccat ctgcgacggc tctgccatca
     9901 tcacaggtgt gttgctggca ttcaacttac cgtctaatct ccctatctgg attatcattc
     9961 tgggtgcact gtttgctatc ggtgtaggca aaatgtcttt cggcggatta ggttgcaatc
    10021 ctttcaatcc ggcactggca ggacgtgtgt tcctgttact ttctttcccg gtacagatga
    10081 ccagctggcc ggtagtcgga cagttgaccg cctatacgga tgctaccacc ggtgccactc
    10141 cgctggcatt gatgaaacaa gcgattcatg ctgcagataa aagtgcggct atggatgctt
    10201 taaaccagat tccggatgca ttgagtttgc tgatcggaca gaatggcgga tgcttgggtg
    10261 aagtgagtgc attggctcta ttgatcggac tggtttatat gctctggaag aagatcatca
    10321 cttggcatat tcctgtgtct atcctggcta ccgtgtttat ctttgcaggt atcatgcact
    10381 tggcagatcc ggaaaaatat gtttctccga tattgcagtt gctctccggt ggtctgatgc
    10441 tgggtgctgt ctttatggca accgactatg tgacttctcc gatgagtaag aaaggaatgt
    10501 tgatttatgg tgtatgtatc ggtctgctga cggttgtcat ccgtctgttc ggtgcttatc
    10561 ccgaaggtat gtcgttcgcc atcctgatta tgaatgcgtt cactccgctg attaacacct
    10621 attgtaaacc aaaacgcttt ggggaggtag cgaagaagaa atgaaaaagt tagaatcatc
    10681 tttaaagaat atgttgctgg tacttacggg cgtgactgct gtctccgtag cgttgctggc
    10741 ttatgtaaat gaactgacaa aaggccccat tgccgaagcg aatgcgaaga cactgaacga
    10801 ggctttgaaa aaggttcttc ccgaatttac caataatccg gtagcggaaa gcgatacgat
    10861 cttcagcgag aaagacggaa agaagaatgt tgactttatc gtttatccgg ctaagaacgg
    10921 cgaagaattg gtaggaacgg ccgtcgaagc taaatcaatg ggatttggtg gcgaactgaa
    10981 agtgttggta ggctttaacg ccgaaggtaa aatctataat tactcgttac tcgctcacgc
    11041 ggaaactccg ggactgggtt ctaaagccga caaatggttc ggagcatacg acccggccaa
    11101 gggagaacag gctgtgtctc atgaagagag taaaaagtct attttgggga tgaatccggg
    11161 tgaagctccg ttgaccgtca gcaaagatgg gggagcggtg gatgccatta cagcttctac
    11221 cattacttca cgtgcgtttt tgaatgctgt aaatgctgct tatcaggctt ataaggcaga
    11281 aggtggtaaa gtgaatggtg tcagcggtgc ttctcaaaag gctacaggcg cagactctga
    11341 cactgctacg ggagctacga taaaagttga acttactgat tcggtcagtg ctaaataaga
    11401 aaggagacag atatgaataa ctttaaagta atgatgaacg ggattatcaa agagaatcct
    11461 acgtttgtac tcctgctcgg tatgtgtcct acattgggta cgacttcgtc ggccatcaat
    11521 ggtatgggta tgggactggc taccatgttc gtattgatct gctcgaatgt ggtgatctct
    11581 ttaatcaaga acctgattcc ggatatggtg cgtatcccgt cgtttatcgt ggtgatcgcg
    11641 tctttcgtaa ccttgcttca aatggtgatg caggcatacg tgcctggact gtacgctacg
    11701 ctcggacttt tcatcccgtt gattgtagtg aactgtattg tgttgggacg tgccgaagca
    11761 ttcgccgcca agaataacgc agttgcttct atgttcgacg gtatcggcat gggacttggt
    11821 ttcaccattg ccctgacatt gctgggggct gtccgtgaat ttctgggaac cggtaagatt
    11881 ttcgatctga ccatcatgcc ggaagaatat ggaatgttgg tatttgtatt ggctccgggt
    11941 gctttcatcg ctttgggata cctcattgcg ctgattaaca gtttcaagaa agcctaattc
    12001 aattaaataa gaaaagaata tggaatatat attgatattt atttcggcaa tctttgtaaa
    12061 caacatcgtg ttgtcgcagt tcttgggtat ctgtccgttc ctgggcgtat ctaagaaagt
    12121 agagactgcg atgggtatga gcgctgcggt tgctttcgtg ttgaccatcg ctaccatcgt
    12181 taccttcctg attcagaagt ttgtgttgga tgttttcggg ctgggatatt tgcagacgat
    12241 tacgttcatt ctggtcattg ccggattggt gcagatggtg gaaatcattc tgaaaaaagt
    12301 atcgcctgct ctgtatcagg ctttgggcgt gttcttgcct ttgattacaa ccaactgttg
    12361 tattcttggt gtggctatcc tggtgattca gaaagactac gacctgctga caggtgttgt
    12421 gtacgcgttt tctacggcca tcggtttcgg tctggcactg gtgctttttg ccggattgcg
    12481 cgaacagatg agcctcgtga aagtacctaa aggaatgcaa ggcactccga ttgccttgat
    12541 taccgccggt ttgcttgcta tggcattcat gggattctcc ggcgtggtgt aaggatttac
    12601 agttgataat taaatagggg attggaagct ctgttgtatg tcgccataca gctttgagtt
    12661 tccaattctt ttttatacct gattaccacc aaattgtacc ttaataactt ttcagcaaat
    12721 aaaattgtgg caaattattg ctattccatt ttatttccat acatttgtaa ctcaaacaat
    12781 aataagccga gaaactaacc atttttataa agtatatgaa agaaagaatt ttagtaacag
    12841 gcgggacagg atacataggg tctcatactg ttgtagaact acaaaacagt ggatatgaag
    12901 taatcatcat cgataattta tcaaattcaa gtgctgacgt tgttgacaat atagagaaag
    12961 tttccggtat tcgcccagtt tttgaaaagc tggattgcct ggactttgct ggtcttgatg
    13021 cagtatttac aaaatataaa ggaattaagg cgatcattca ctttgcagcg agcaaagcag
    13081 taggagaatc ggtacagaaa ccgttgcttt actaccgtaa taacctggtt tctttgatta
    13141 accttctcga actgatgcca aaacatggag tagaaggtat tgtgttctct tcttcctgta
    13201 cagtatacgg tcagccggat gaattgccgg tgacagaaaa ggctccgatt aagaaagcgg
    13261 aatcgccata cggaaatacg aaacagatca atgaagagat tattcgtgat acggtagctt
    13321 caggtgctcc gatcaatgcg attatgctgc gctatttcaa tccgattggt gcgcatccta
    13381 cggcattgct gggtgaactg cctaatgggg ttcctcaaaa cctgattcca tatctgaccc
    13441 aaaccgccat cggtctccgt gagaaactaa gtgtgtttgg tgatgattat gatacaccgg
    13501 acggttcttg tatccgtgac tttatcaatg ttgttgactt ggctaaagcc cacgtgattg
    13561 ctatccgtcg tatcttggaa aagacacaaa aagaaaaagt ggaagtgttc aatatcggta
    13621 caggacgtgg cgtttctgta ttggaattaa taaatggctt tgaaaaagcc accggcgtaa
    13681 aattgaatta tcagattgtc ggacgtcgtg ctggtgatat tgaaaaagtt tgggcgaatc
    13741 cggatttcgc aaatcaggaa ctgggttgga aggctgtaga aactttggaa gatactttac
    13801 gttctgcatg gaactggcag ctgaaactcc gtgaaagagg gattcaataa aagagatttg
    13861 ttttaaaata aacataaaag attaaacaaa tcgtgcatgc gatttgttta tctgatgcta
    13921 atcgacctga agctgtttat gagtatgcga atatacgtaa atggtactta tgcctccccg
    13981 gcatagacag gaaagattgc atagtagttt tgtcgtgttt tattttgtgt ttgtgttgtg
    14041 acggtactac gacgtgagtc gtggtaccgt tttttgttcg cccatactgg gcgaacaaaa
    14101 ctatgtttat agctttcctt tgaaatagaa aacgtcgctt tctcccattg tttccggtaa
    14161 agaagttccg ggggcgaaca gtccgaacac tgaagagccg gagccgctca tggaggcgta
    14221 gatcgctcct tgatgataga gttctctttt aatttcccca ataacgggat gttgcgggaa
    14281 tacacttgct tcaaaatcat tgattaggat atccttccat tctgcaactg gacgcaggat
    14341 tgcctctttg accggatatt ccggacggtg gggatgaata tttgaaaaag cttcccgggt
    14401 agaaacgaaa acgttcggtt tgacaatcat gatttggtaa ccgcttaatg aaagctcgat
    14461 tggtgagaac aggtttccga ttccttcggc ataggtcggc ttgtttttaa taaagaaagc
    14521 acagtccgct cccaaagtgg cggcatatac ctccagctgt tcttcggata attccagctg
    14581 aaaatgatcg ttgagcaact ttagcataaa agcggcatcg gatgaaccgc cccccagtcc
    14641 ggctcccgag ggaatatgct tatacaaatg aatttcgaca gggggaagat gaaactcctt
    14701 atccagcaat gaataggcct ttgccaccag gttgtcttcc ggattgccgg ctatctccat
    14761 gccatactgg tggagggtaa tcttcttttc tgtttcagaa gaagtacgga tttcgagagc
    14821 gtcttcgagg gctaccggat agaaaacggt ttccagattg tgatatccgt ccgggcgttt
    14881 ttccgtgatg gaaagtccca ggtttatttt gatattagga aaagcgagca tttgatttat
    14941 gatttatgaa ttatgattta tgggttgcta aattgcgatg ttgtggcact gtctcttata
    15001 cacatctccg agcccacgag acatgcgcag at
//
