LOCUS       c00488_gnlPro..         3669 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNOAIPPO_488.
ACCESSION   c00488_gnlPro..
VERSION     c00488_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:40:37
            Original ID  :: gnl|Prokka|LNOAIPPO_488
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3669
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg488_1"
                     /sec_met_domain="IlvN (E-value: 2.3e-47, bitscore: 148.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.1e-21, bitscore: 65.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACERGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMD"
     protocluster    1..3669
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3669]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3669
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3669
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3669
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(854..1597)
                     /locus_tag="ctg488_2"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             complement(1603..2160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg488_3"
                     /sec_met_domain="ALS_ss_C (E-value: 7.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             complement(2218..3669)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg488_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.3e-49, bitscore:
                     153.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TNTVTGIADAMIDSTPIVVIAGQVGTGFLGTDAFQEVDLVGITQP
                     ITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDFAKNAQIEKTKYEPTKVDFIRSY
                     VPVPDTDEESVQAAAELINNAERPLVLVGQGVELGNAQSELREFIEKADMPAGCTLLGL
                     SALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGMRFDDRVTGNLATYAKQAKVIHF
                     DIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTHTEWIDSFKEYEKVEEEKVIRPE
                     LHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMISARYFKYTKERSIITSGGLGTM
                     GFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGTIMEQKAPVKIICLNNNYLGNVR
                     QWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFTREELKEAIAEMLATDGPFLLEA
                     CVVEEGNVLPMTPPGGSVNQMLLEC"
ORIGIN
        1 gtccataccg ttctttgcaa acaacggcat caatgactgt gtcagttctt ccactgtttc
       61 attgaatgct tcagaaggac tatgaccgtt ttcacgcaat acttcgtact gtgccagcaa
      121 caaaccttgg atagcaccca tcaatgaacc acgttcacct gtcaagtcag aagtagcttc
      181 acgttggaaa gttgtttcga acagataacc ggaaccgata ccaataccca gtgcgatggt
      241 tctttcgtaa gccttgcctg tagcatcctg atagatagca taagaagagt tcaagccacg
      301 tccttcgagg aacatagtac gcaaagatgt acccgaacct ttaggagcaa ccatgataac
      361 gtcgatatca gcaggaggaa ctacacctgt acggtcgttc caagtgatag caaaaccgtg
      421 tgagaaataa agagcttttc cagcagtcag gtaaggcttg atagtaggcc atactgacat
      481 tactgctgcg tcagacaaca gacacattac aatagtacct ctctcacaag cttcttcgat
      541 accgaacaaa gtttcacccg gaacccatcc gtctgctact gccttatcgt atgtttttcc
      601 ttcacgttga ccaacgatta cattgaaacc gttatcacgc aagttcagtg cctgtccagg
      661 accctgtacg ccataaccga ttacagcgat tgtttcattt ttcaatactt cacgagcttt
      721 ttccaatgga aattcgtcac ggattactac agtttcagta gtacctccaa aattcaactg
      781 tgccattttc tttttgtttt tagtttttga tgacttacgc catctgttat taattgattt
      841 tatattctca catttattca aatatcactt tcgagcggca aacaacttcg ttgccattct
      901 tcttcacttc tacgtgaaac tcgtttgcat tcacttcatc gcagaagaaa gagagttcat
      961 caccaaaata gctttccgcc acatacgcca tttcaaaacg acggatacgt ttggtcttat
     1021 acaattcaat cgggaacaaa tcaaggatat gctcgatgta acggatgctg tttacatgac
     1081 cgttgatatc tatatcactg tattttgccg tcagggtagc tatcggctga tcgcttgtca
     1141 ctttgatgcg tgaaggcttt tcaatcgggc aaggctcatc acagacatag tctacgatac
     1201 ttcccccatg caaagtcaac aagtcggcag gcttgcgggt attaagatta atcattgccc
     1261 atacggaacg tgcgtagcca atcttcttcc catccttatc aataatagca aaattacggt
     1321 ccgtaaacaa acggtagaca ttttccaccc acgtctgaac cgagaaattc tcatactgat
     1381 aaggcatttc atccaactca atagccagac gtgaaagcac ccatgtgtaa ttatcctcat
     1441 tcagcgttgc aataccaaaa ccacggtcat tggcgtgaaa acctgcacaa ttcagcagat
     1501 gatttcccag tacccccata gtcagacgtc cgttgaagtc aacatggaac ggttctgcca
     1561 caaactgata agtccctatt ctattttctt cactcattat tcttattggt ttttactttg
     1621 gttatacata gcttcccgtc catcgagaaa ctcattcacc cgttcaaagc agctggtagt
     1681 aatcgctaca cgtcccgaac gaacaaactg caaaacacaa ttcaaagcct tcagttcacc
     1741 atagagcgaa gttatatctt cgctcattcc atttttctcg acaatagaaa ataccggatt
     1801 gacttccact atacgtgcat tgtatctacg aatcagtttg gatgcttccg gattctcctg
     1861 aaaagcagga gtagacacct tatataatgc aatctcgtgg aaataaatct catcctctgt
     1921 gaaataatgt gcctgaatca cgtcgatctt cttttcgatc tgtttcacta ccttctcaat
     1981 gatgtcctta tcagtccagg ctgttattgt atacttatgt acacctttaa tagaagaagc
     2041 agatacattc aggctctcaa tatttatttg ccgacgggta aatacagcag ttacctgatt
     2101 cagcaatcca gctatattct ccgaatgaac aatgattgta tataacgttt tatcactcat
     2161 aactctaatt ttttaaatgc gaactctcaa ctctccattc tcaactctca acttctccta
     2221 gcactccagc aacatctggt ttactgaacc acccggagga gtcatcggca aaacattgcc
     2281 ttcttccacc acgcaagctt cgagcaggaa cggaccgtcc gttgccagca tttcagcaat
     2341 agcttccttc agttcttcac gagtgaaaac acgcttggaa ggaatatcat aagccgaggc
     2401 cactttcata taatccggat tcaacatcgg ggtaaacgaa tagcgacggt tgaaaaacat
     2461 agcttgccac tgacgtacgt ttccgaggta attattgttc aggcagataa tcttcaccgg
     2521 agctttctgc tccataatcg tacccagttc ctgaatattc atttgcagtc cgccatctcc
     2581 cataaatacg catacggtac gttccggtgc tccgaaagtt gccccgatag ctgcgggaag
     2641 cccgaagccc attgttccaa gtcctccgga agtaatgata ctgcgttctt tcgtatattt
     2701 aaagtagcgt gcagatatca tctgattttg acctacatct gtaaccaaaa cagcttcatg
     2761 atgagtagcg tcacttaccg cacgtaccac ttcccccata ctcaacgagt ttgtggcagg
     2821 atgaagttca ggacggatta ctttttcctc ctctactttc tcatattctt tgaagctatc
     2881 aatccattcg gtatgagtgt tctttttcag gagtttcgtc acagaagcca gtgtttcctt
     2941 gcaatctccc aatacagcta catctacctt tacattctta ttaacttccg caggatcgat
     3001 atcaaaatga atcacttttg cctgtttggc gtaagtagcc aaattaccgg tcacacggtc
     3061 gtcaaaacgc ataccgacag caatcagcac atcacattta ttggtattga tattcggtcc
     3121 cagattgccg tgcataccca acataccttt attcaacgga tgttctgtcg gcaaagccga
     3181 aagcccgagc agcgtacaac ccgcaggcat atccgctttt tcgataaact cgcgcaattc
     3241 gctctgtgca tttcccagtt caacaccttg tccaaccaat acaagcggac gttcagcgtt
     3301 attaatcagt tcggcagcag cctgtacaga ctcctcgtcc gtatcgggaa caggaacata
     3361 actacggata aaatcgactt tcgtcggttc gtatttcgtt ttctctattt gcgcattttt
     3421 ggcaaagtcc agtaccaccg gccccggacg accactacga gcaatgtaaa acgcacgtgc
     3481 taccgcccag gctacatctt ccgcacggcg aatctgataa ctccatttag tgattggctg
     3541 ggtgatacct accaagtcaa cttcctgaaa agcatcggtc ccaagaaagc ctgttcctac
     3601 ctgtccggca atcactacga taggcgtact atcgatcatc gcatccgcaa tgcctgttac
     3661 cgtattggt
//
