LOCUS       c00003_gnlPro..        13739 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIOMLBID_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:53:45
            Original ID  :: gnl|Prokka|AIOMLBID_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13739
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13739
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[253:3739]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      254..3739
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13739
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(254..1009)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1"
                     /sec_met_domain="Fer2_3 (E-value: 2e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.7e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.1e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPTTGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(1037..2980)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.3e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.3e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(3014..3739)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="SucD_FumR (E-value: 5.2e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             3811..3927
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MLNTRITQTIKEIFRQSNLYISGGTNGKSYSINKLTKM"
     CDS             4128..5375
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTP
                     LLAVYGMKLGGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSG
                     HTATAFMAATIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGIL
                     STELGYFLADLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLS
                     SPGATNVSVKGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRIHADPTG
                     VFTFTAGPYFSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKHPPCGTINNIAFMKGN
                     GSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKH
                     KIHYFTIGATVTALFW"
     CDS             complement(5379..7298)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MVFSCLLKGFRIRKHFFKRFPIFVTPIKYNTCMNKTILLVVFCFS
                     LFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIKSDLALNPEMLRLHNYLLKQCDDLITTP
                     VLAYKKEGKRLLAVSREALRRIFYLSYAYRMTGEDKYRLRAEQEMIAVCSFADWNPSHF
                     LDTGEMTMAVAIGYDWLFDRLSPDARRLVQEAILNKGFAPSRDKRYNWFLRATNNWNQV
                     CNAGLVYGALAVLEDHLEEAREIIERALYTVGLTLKGYGPDGAYPEGYNYWGYGTTFQV
                     LLNAALESALGTDGGLSSAEGFLASARFMQFMTGTTGKCFNFSDSRETVFALPAMYWFA
                     DKLQDPTLLWNEKDMLSRAELSFSDEESRFLPLIPIYGSQYKMNELVPPAMKLWAANGQ
                     TPVVLVRTGWENGEGFYLGIKGGTASTSHAHMDAGSFVFDALGVRWVQDLGMQEYYSLE
                     KENVDLWNMSQNGQRWNVFRYNNLAHNTLTVNGKYHDVKGFVPVTNIYSEAHKLGASLN
                     MTDLFGGELENAVREVALINEKYLSVIDRVKAGSQPATVRWTIVTGAIPRVLDSHMVEL
                     TKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDASNEGTCRIVFDVSLESGQESDIKVRLV
                     PAAD"
     CDS             complement(7486..7644)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MCCWDLVWIFTYSGDKMCCLACDLRSQGLFKITFLDRINNFFIYN
                     KSLFHLK"
     CDS             7933..8409
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MKTLVHTEKEHIEEIIRSCDVCFVGLADTDGTPYVIPMNFGYRNG
                     VIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHPEVACSYRMRSKSVIAWGKVRFE
                     EDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLVDLDEVTCKEFGAPHKKY"
     CDS             8430..8900
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIADKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             8959..9858
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     QILSQAKKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVITQNKVTK"
     CDS             9905..11482
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDKEVLYRAN
                     FCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSEDFNHSKF
                     VAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESLHKRGYRV
                     EQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGIHRKEFAF
                     EKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIETAQKNIRSAGLAKYVELKTM
                     PFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWILSYKDECF
                     DKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSASRPRPSFP
                     EKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERGDGRPARK
                     QFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRPFKKPFRR
                     EDNDDFED"
     CDS             11466..13682
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MTLKIKHFLVLCVFALSTSMTLMAQDKQLTLHDLLPGGKTHNKFV
                     PASLKQLQWCGDTYLYVKGDSMICGVPEKKEQVAFTRSRLNEALSATGLPTVGSLPGFS
                     VPYKDQPVLAFTSKGHRLHYNFAENKIIGNYQLDSKGSNYNFCPANNCLAFTVGNNIQI
                     LSPENQTSIVTRETKNGIVCGQAVHQREFGISKGLFWSPAGSALAFYRMDESMVTDYPI
                     VNIDARQAKAEPVKYPMAGMKSHEVTVGVYNLSTGETVWLETGTPKEKFLTNIAWSPDE
                     KSIYIAELNREQNEMNLVRYSALTGKKEAVLFTETNEHYVEPQYPVLFLPNDPGKFIWQ
                     SQKDGYNHLYLYDTTGKQLKQLTQGEWVVTQVIGFDAKGENLFITSTQPHIRSSFNYGT
                     PMNVNGWKLNLKKGETSLLTPNAALESVHNLSVSASGKYAIDSYDAPKIPRIINLIRTK
                     DGKEIKNLLTARDPYKGYTLPEIEAGTIKSADGTTDLHFRLVKPVGLDENKKYPTIVYV
                     YGGPHSQLVTGGWQNGVRGWDIYMAQRGYVVFTVDNRGTSNRGFAFESVIHRNLGVNEM
                     ADQMKGVEYLKSLPYVDADRIGVHGWSYGGFMTTNLILTHPDVFKVGVAGGPVIDWSNY
                     EIMYGERYMDRPQDNPEGYKNANLKLKAGNLKGHLLQIHGDIDPVVVWQHSLGFLKACV
                     DADTYPDYFVYPRHEHNVTGKDRPHLYEKITRYFDDYLKNTNKE"
ORIGIN
        1 tgtctcacga caagccctaa ccaactttgt taaccttaaa tctaatacta ttatgaaaaa
       61 accacagtac aaagatacag gtattctcca acttgtcaat agttaaaatg ctaattagtg
      121 ttgtatagca tataagaaac actaacaaca ttcaagatat ttatctatga cttcagaaat
      181 gttaaaatag gggcaaaaaa gaagaggcgc tgccataagc aacgcctctc cggacataca
      241 tatataatgt atattagtct tgcaatttag cacaaatgaa ctcgcggttc aaacgagcga
      301 tgttgctgac agagatgttc ttcggacatt ccatttcgca agcacgcgtg ttggtacagt
      361 taccgaagcc cagttcgtcc atcttggcaa ccattgcttt cgcacgacga gcagcttcta
      421 ccttaccctg aggcaacaga gccaactggc taacctttgc agaaacgaac aacatagccg
      481 aaccgttctt acaagcagca gcacaagcac cgcaaccgat acatgcagca gcatccatag
      541 ccatttcagc atctgcacga ggaatagcga ttgaattggc atcaggtaca ccacctgtgt
      601 tcactgatac gaaaccacct gcctggataa ttttatcgta agcataacgg tctaccatca
      661 agtcgcggat taccgggaaa ccggcagaac gccacggttc gattgtaata gtttcgccat
      721 cattgaagcg acgcatataa agctggcaag tagttgcgcc ggttgtaggt ccgtgcggat
      781 gtccgtttac atacaaagaa cacataccgc agataccttc acgacagtcg tgatcgaata
      841 cgatcggctc tttaccttca ctgaccaaac gttcattcaa aatgtctaac atttccagga
      901 aagaaacact ctgattgatt ttgtctattt ggtaagtctc aaattgtcct ttatctttcg
      961 gacttttctg acgccaaact ttaagtgtta cttttatatc tttatccatg attctaattt
     1021 ttgtgattga tgattattac ttcttgtagt tacgtgtttg aggaacaacg aactgatagt
     1081 tcaaatcttc cttcagcata accggatctt tgtcttcacc ctggtattcc caacaagata
     1141 cgtacatgaa cttatcgtca tgacgcaggg cttcgccttc ctcggtctgg tgctctgtac
     1201 ggaagtgtcc tccacaagat tcggcacggt ccaatgcatc gtgtgccatc aatgtaccaa
     1261 tctcaataaa gtcagccaaa cgcaatgcct tatccaactc tacgttcagg ttatcggctt
     1321 cacccggaat atatacatta ctccagaact ctttcttcag ctctttcaac atctggatcg
     1381 cttcctgcaa accttttgca tcacgtgcca tacctacatg ttcccacatg atatgaccca
     1441 gtttcttatg gatagaatct accgactctt tacccttgat actcatcaat ttcttgatgc
     1501 ggtctttgat acccttttca gcttctgcaa actcaggcag gtcggtgctg aaacgtggaa
     1561 cctggatctg gtctgacaga tagttctgaa ttgtataagg caatacaaag tagccatcgg
     1621 ccaatccctg catcaacgca gaagcaccca gacggttagc tccgtggtca gagaagttag
     1681 cttcaccgat agcgaacaga cccggaatag aagtcatcaa ttcatagtca acccacagac
     1741 cacccatcga gtagtgcaat gcaggataaa tcatcatcgg agtttcgtat ggatcgtcgt
     1801 tggtaatttc ttcgtacatg tcgaacaagt taccatattt agcttttaca acatctttac
     1861 ccagacggtt gatagcgtcg gagaagtcga ggaacacggc cagacctgtg ttgttcacac
     1921 cgaagccggc gtcgcaacgt tctttagcgg cacgtgaagc cacgtcacgc ggaaccaggt
     1981 taccgaatgc tggataacgg cgttccagat agtagtcgcg gtctgcttca ggaatgtctt
     2041 tccctttctt agttccggcc tgtaatgctt ttgcatcttc cagtttcttc ggaacccaga
     2101 tacgaccgtc gttacgcaat gattcagaca tcaaagtcag cttagactga tagtcacctt
     2161 tcaccggtac acaagtcggg tggatctgca ccatacaagg gttagcgaag taagcacctt
     2221 tcttgtagca ctgccatgca gcagaaccgt tggaagccat tgcgttagta gacaagaaga
     2281 aagtatttac ataaccacct gttgccacca ctactgcgtg agcagagaaa cgttcgatct
     2341 gacctgtgat caggttacgt gcgatgatac cgcgggcacg gccatccacc ttcacaacgt
     2401 ccagcatttc gtggcgggta tacatcttta ctttgttcaa accgatcata cggctcaaag
     2461 cagagtaagc acccagcaac aactgctgtc cggtctgacc gcgggcatag aacgtacggg
     2521 atacctgagc accaccgaat gaacggttat ccagcagacc accgtattcg cgagcgaaag
     2581 gaacaccctg tgctacgcac tggtcgataa tagagttgga aacttcagcc agacgataaa
     2641 cgtttgcttc gcgggcacga tagtcaccac ctttgattgt atcgtagaac agacggtaaa
     2701 cagagtcacc atcattctga taattctttg cagcattgat accaccctgt gcggcgattg
     2761 agtgtgcgcg acggggagaa tcctggatac agaagttcaa tacgttgaat cccatttctg
     2821 ccagagaggc agcagcagaa gcaccggcca gaccagtacc aactacaatc acgtccagac
     2881 gacgtttgtt cgcggggttc accagtttct gatgatcttt ataatttttc cacttctcag
     2941 ccaacgggcc ctgagggatt ttagaatcta tttgagtcat aatgatttat tttcaatatt
     3001 gttacacctt aaattaatgt cctgcacaaa cagctacata gtcaccacct acaccattca
     3061 ggtagaaaac gatagtaatg atagcaaaca ctacgcaaat aacggttgct acaatcttgg
     3121 aaatgcagat ccaacggttc atccagatcg tgttactcca accgatagtc tgaatagcgc
     3181 tccagaaccc gtgagtcagg tggaaccaca aagctacgta ccataccaga tacagcactg
     3241 tattcaggat attaccctgg aaatagtagt tgataaacgc tgcaccgtcc tgaggagata
     3301 cggttgttgt tccgtcgcaa agtgttacca tgtgattgcc taggagttcg gcgaacatca
     3361 tcttatacca gaactggctg aagtgcaaca ccatgaacag gataatgata atacccagta
     3421 ccagcatgtt ctgagatgcc cattccacac ctttcggacg agcgttaatt gcataacggt
     3481 cgttaccgcg agccttacgg ttttgcagtg taaggagaac agcatacaca aagtgaatca
     3541 caacgcctgc tgccagcacc aatgttgctg ccacggcata ccaatttgct cccaacaatg
     3601 aacaaatcat gttataggct tctcccgaga aagcagccgc cacattcatt gacaagtgga
     3661 acaataagaa caaaacaaga aaaaggcctg atacactcat tatcagcttc ttcccgatag
     3721 aagaattaag taaccacata agataataat ttaagttatt taattgtttt tagaaattca
     3781 tatcaatata ctcaattatc aggcaaaggt atgctaaata cacgtatcac gcaaacgatt
     3841 aaagaaatat ttcgtcaatc aaacctatac atttcaggag ggacaaacgg taaatcctat
     3901 tcaataaata aattaacaaa aatgtaacca gtactaaccg gcatttttat atcttcgtgg
     3961 cataatcagg ggatcgtatg ttacaacgta aaatgctgag cttcttattt atgatgattt
     4021 ttataccgtc tgttcgtgct cagtggaaag atagtacgag attcataaat aaagaacatg
     4081 aatttgaaac cacttacaac aaaatatcag agaataaggt ataccagatg ctacgtgtcc
     4141 ctgttcctct tttcgccatt tcagccataa catatgggca gggtgataaa ttccggacat
     4201 tgcgcaatac gcatacgccc aacttccatt acagatacga tgattttctg caatatactc
     4261 cgttgcttgc tgtttacggg atgaagctcg gcggtgtgga aagtcgtagt tcatggcccc
     4321 ggatgatcgt atcgaacgct ttttcggcaa cgatcatggc cgctaccgtc aacagcatga
     4381 aatatacgat caaacgcgaa cgccccgacg gctcaaagaa caactcattc ccttcgggac
     4441 acacggcaac cgctttcatg gctgctacca tcatgcaccg ggaatatggt ctgacccgca
     4501 gcccgttata tagtatcggg ggatatacag tcgccacagc caccgctttc agccggcaac
     4561 tgaacaaccg ccactggctg agcgacgtac tggccggggc tggtatcggc atcttatcca
     4621 cagagttagg gtattttcta gcagacctga tcttcaagga caaaggcttg aatctccctg
     4681 acaagctcag ggagtctgcc cccaaaggag ggcgcccttc tttcctggag ttcgccgtag
     4741 gatacagtat catcaacgga agtatcgagg taggtaaaaa tatacgcctg agctcgccgg
     4801 gagcaaccaa tgtcagcgta aaaggcggtt acttcttcaa tccttatttc ggtatcggcg
     4861 gcgaaataac agcgctggca agcccgatgg cattcgacat gtcgctttat acaggaacaa
     4921 ccccttcaac caaatatgac atcacccgca tccatgccga tccgaccggt gtttttactt
     4981 ttacggcagg gccttatttc tcgttacctg tagccagtaa attgctttta ggaacaaagt
     5041 tccaggccgg atattcctac ctggtgaaaa atgaagtgga aatggactta caggaaaagc
     5101 accccccatg cggaaccata aataatattg cttttatgaa aggcaacggt agcagcaact
     5161 atgttttacg cacaggcatt tcagcgaccg gaattgtcag ccgcaacctg ggtatccgta
     5221 tgttcgtaga ttacgattat acgttcctga aagcacctta cgaaatctta accagcctca
     5281 gagacagcca accagtctac ggcgagagcc atttaagcaa gcacaaaata cactatttta
     5341 caataggggc aaccgtaacg gcgctgttct ggtaattatc agtcagcagc aggaaccagc
     5401 cggactttga tatcgctctc ctgcccgctt tccagactta catcgaaaac gatacggcag
     5461 gttccctcat tggaagcatc atagctattc ttcgatacat tatcaaggac ggacacagaa
     5521 gttacggatg gactatcgac gatcagttgc atacatttgc cgtcttttgt cagttccacc
     5581 atatgactgt ccaatacacg gggaatggcc ccggttacaa tcgtccatct gacagttgcc
     5641 ggctgactgc cggcttttac acgatcaatc accgacagat atttttcatt gatcagagca
     5701 acttcacgga cggcattttc caattctccg ccgaacaagt ccgtcatatt cagagaggct
     5761 ccgagtttat gcgcttccga atagatattt gtcacaggta caaaaccttt tacatcatgg
     5821 tatttaccgt ttacagtcag tgtattatgc gccaggttat tataacggaa cacattccag
     5881 cgctgcccgt tctgcgacat attccataaa tctacatttt ccttttccag cgaataatat
     5941 tcctgcatcc ccaggtcctg cacccagcga acacccaaag catcgaacac aaacgatccg
     6001 gcatccatat gggcatggct ggtcgaagcc gttcctcctt ttattcccag atagaaacct
     6061 tctccattct cccatcccgt acggaccagc acgacaggcg tctgtccgtt agccgcccac
     6121 aatttcatgg caggaggcac cagttcattc attttatatt gtgaaccata aatcggtatc
     6181 aacggaagga aacggctctc ctcatccgaa aaagacaact ccgcccgact caacatatcc
     6241 ttttcattcc aaagcagtgt agggtcttgc agcttgtcgg caaaccagta catagccggc
     6301 aaagcaaaaa cagtctcacg ggaatcgctg aagttaaagc atttaccggt cgttccggtc
     6361 ataaactgca taaaacgggc agaagccaga aaaccttcag ccgaagagag accgccgtca
     6421 gtccccaggg cggattccaa cgctgcattc aaaagaacct ggaaggtagt cccgtatccc
     6481 caataattat atccttcggg ataagcgcca tcgggaccat agcccttcaa agtcaagccg
     6541 actgtataca aagcacgttc aatgatttca cgggcctctt ccagatgatc ttccaacaca
     6601 gccagcgcac cgtaaaccag tccggcatta cagacctggt tccagttatt ggtcgctctc
     6661 agaaaccagt tatatctttt atccctcgac ggggcaaaac ctttattcag aatcgcctcc
     6721 tgcaccagcc tccgggcatc cggagataac cgatcgaaca accagtcata accgattgca
     6781 acggccatag tcatttctcc cgtatccaga aaatgagacg ggttccaatc ggcaaacgaa
     6841 cacacggcaa tcatctcctg ctctgcccgc aaacgatact tatcctctcc tgtcatccgg
     6901 taagcatatg aaagatagaa gatacgccgc aaggcttcac gcgatacggc cagcaaccgt
     6961 ttcccttctt ttttatatgc cagcacaggc gtcgtgatca gatcgtcgca ttgcttgaga
     7021 agatagttat gcaaccggag catttccgga ttaagagcca gatcggattt aatcttttgc
     7081 tcctctcctt tcttcaccag caaccgggga tgagaagggt aagaatcaaa gcgtattccc
     7141 tgtgaatacc ccgaaacgaa cagggaaaag caaaacacaa caagcaggat agttttattc
     7201 atacaggtat tatatttaat tggagttaca aatataggaa atcgcttgaa aaagtgtttt
     7261 cttatccgga atccttttaa cagacaagaa aataccattt tgctacaatt tacaacgatt
     7321 aaagatcatt ttgtatattt tttccgcata tacgtatctg ctatatttca caaaacagta
     7381 gaaatagaag atccgaaaac acaatattta acacttaacg tattcatata gattttcact
     7441 cttcatttta aacaaattgt aatctcgttt aaaacgaatt ttttttcatt ttaaatgaaa
     7501 tagagattta ttgtagatga aaaaattgtt aattctgtcc aaaaaagtta ttttaaacag
     7561 gccttgggac ctcaaatcac atgctaaaca acacatttta tctccagaat aagtaaatat
     7621 ccagaccaaa tcccaacagc acattcacat atttcaaatg tactttacga catttatcaa
     7681 cgactaccac acatcatcaa acataaagct acatttatta atcaacaatt aaaataaaga
     7741 cattcgcaat catcccgtag agcgaataaa aacaacaaac ccgatttagg acacgtacag
     7801 ctcactgaca gaaggactat ttgacatttt gacacattga cgaaaacagt acatatataa
     7861 taaagtcgca aaagtaagtc cgagaagttg aactttttta ctatgtttgc aaaagcataa
     7921 ttaaaaatag taatgaagac actggtacac acagagaaag aacatatcga ggagattatc
     7981 cgtagttgcg atgtctgttt cgtcggactg gctgatacgg atggtacgcc ttacgttatt
     8041 cccatgaact ttggctatcg gaacggtgtt atctatttac attcagcgca ggaaggccga
     8101 agtatctcaa tcctggaacg taacccgaag gtttgcatca ccttcagcac cgaccatgat
     8161 ctggtattcc agcatcccga agtggcttgc agctaccgta tgcgttccaa aagcgttatc
     8221 gcatggggta aagtgcggtt tgaagaagac ttcgacaaga aaacggaagc gctggatata
     8281 attatgaaac agtattcgga caaggaattc cgttattccg acccggctgt gaaaaacgta
     8341 aaaatatggc tggtagacct cgatgaagta acatgcaaag agttcggggc accgcacaag
     8401 aaatactaaa catttaagag agtgaatata tgaaaaatct gttagcaata tttttaatgg
     8461 tgttcctgtt cgcttcatgc gaaggaccga tgggccctcc gggacgagac ggggaagacg
     8521 gcggtataac ctactggata tttgacaagg atatacaagt taagtcaagc gactgggaat
     8581 tagtcgacaa tggtaataac gaaccttttt acatgtatga gtacagaatt gccgataaag
     8641 atttcgacat atatcaggat gcttataaag aaggcttaat tacctgttac atgtatctgg
     8701 atcacggcga agacaaagaa gcacaaactg cattacccaa ccctgtcaat cgaatagata
     8761 aagagaataa tatctggacg gaaacctatg cagccgaata caccaaagac ggtttcatca
     8821 tcttcaaagt gacattctcc gacttcttta ctgatcaacg gccgccggaa acgcatttca
     8881 aagcagttat aacctattaa aagtacacat atatcagata tttaatgtac ttttgcccaa
     8941 aataagactt tcgaaataat gggattgcaa aagcatagca aggtattgaa tgaaacagta
     9001 gaaaagctgt cggacgaatg ttcatacaaa caactgtttc atgcctaccg cgatgaagag
     9061 gcattgcctt caggtgaagt actggaggag attattgact tgtgccgtgc aatcctgttt
     9121 cctggctatt acgggaatgc gcggatcagt acacagacga tccgtttcca taccggggtc
     9181 aatattgaaa agttgcacga gctgctcagc cgtcaaatct atgcgggcct ttgcctggcc
     9241 gacaccagct gtacttcctg tgcggaagag cagatcctca gccaggcaaa aaaactttcc
     9301 gaagcgttca tttccacact gccggaaatg cgctgtctgc ttgccaccga tgccgaagcc
     9361 gcctacaacg gcgatccggc agcacaaaac atcaatgaag ttatcttctg ttacccgggc
     9421 ttccgggcaa taggcaatta tcgtatagcg caccagcttt ataagttggg cgttcctttt
     9481 ataccccgga tgatcaccga aatggctcat tccgaaaccg gtatcgacat tcatccggga
     9541 gctcagatag gacattattt ctctatcgac cacggcacgg gtaccgtgat cggcgaaacc
     9601 agtgtgatcg ggaataacgt acgcatcttc cagggtgtca gccttgccgg agagaagctg
     9661 ccacccgatg agaacgggaa cgcgatccgc ggtgtccccc gccatcccat cctggaagac
     9721 aatgtgaccg tctattccaa cgcgacgcta ttggggaaaa tacgggtcgg caaaggtgcc
     9781 acgatatgtg gcaacgtctg gatcaccgga gatgttcccc ccggtgctgt cattacacaa
     9841 aataaagtaa ctaaataaat atcttttctt acaacgcacg caaatgaata acgagacatt
     9901 tgaaatggtg gccaaaaccc tgtacgggtt agaagaaata ctggccggtg agttattagc
     9961 tataggcgcc aacgacatag aaattggccg ccggatggta tccttcacag gagataaaga
    10021 agtgctttac agagccaact tctgttgccg caccgcctta cgcatcctga aaccgatcta
    10081 tcatttcaag gcaaaagatg ccgatacggt ttataaggaa gtgaaaaagg tcgtatggga
    10141 aaactatatg tcactggaca agacgttcgc gatcgactcc gtgatctatt cagaagattt
    10201 caatcactct aaattcgtgg cttaccgtac aaaagatgcg atcgttgact actttatgga
    10261 gaagcacaac aaacgtcctt ccgtacgtgt gaacaatccc gacttataca tcaatataca
    10321 tatctcgcac aacgattgta ccttgtctat cgacagttcg ggcgagagcc ttcacaaacg
    10381 cggataccgc gtggaacaga ccgaagcacc gctgaacgaa gtgctggctg ccggtatgat
    10441 cctgaagaca ggctggaaag gcgaatccaa tttcgtcgac ccgatgtgcg gttccggtac
    10501 gctgctgatc gaagcggcta tgatcgccct gaacatcgcc ccgggtatcc accgcaagga
    10561 gttcgctttc gagaaatgga tcgacttcga ccaggaactg ttcgaccgca tctataacga
    10621 cgaaagccag gaacgcgaat tcactttcaa atgctacggt tcggatatca acccggccgc
    10681 tatcgagacc gcccagaaga atatccgtag cgcaggcctg gccaaatacg tcgaactgaa
    10741 aacgatgcct ttccagcaat atacggaagc accgcaaccg ggtatcctgg taaccaaccc
    10801 gccttatggc gaacgtatct cctcccgcga cctgctggga ctttataata tgatcggcga
    10861 acgcgtcaaa catgtgttta ccggatataa agtatggata ctcagctaca aagacgaatg
    10921 tttcgacaag atcggcctgc gtcccagcga acggatgaag ctgatcaacg gctcgctcga
    10981 ctgcgaatac cgttgttacg aaatatttga aggaaagaac aaagactata agaaagcatt
    11041 gaacgaggaa ggcgcggaaa gaacggaaga ttccgcctca cgcccaaggc cctcgttccc
    11101 agaaaaaaga tatgacaccc gtcctgcagg tcgcccgaac ttcaagaccg accgcatgga
    11161 ccgccccgac cgtcgtttcg ccgccgctca cagtgaagac gaaaacgaac gtacatccgc
    11221 agcaccggga aaacgtttct tcggtgaaga acgcggtgac ggccgtcctg cccgcaaaca
    11281 gttcggaggc gaacgtggtg aacgcccggt tcgtccgatt ttgcacaaag ccggcgaaaa
    11341 acgccccgtc aaaatgcgtt acaaagacga agacgacagg ttctctaaaa acagaaagaa
    11401 cttcggagac agaaaacgcg gagaaggccg tccattcaag aaaccattca gaagagaaga
    11461 caacgatgac tttgaagatt aaacacttcc tggttctttg cgtgttcgct ttatctacat
    11521 ccatgacgct gatggcacag gacaaacaac tcacattaca cgacctgctt ccgggaggga
    11581 agacacacaa taagttcgtc ccggccagtc tcaaacagct acaatggtgt ggggacactt
    11641 acctgtatgt caaaggagac agtatgatat gcggcgtacc cgaaaagaaa gagcaggttg
    11701 cctttacacg cagccgactc aatgaggcgc tttcggcaac cggacttccg acggtaggca
    11761 gcctgcccgg attttcggtt ccctataagg accagccggt actggctttt accagtaaag
    11821 gccaccgcct gcattacaat tttgccgaaa acaagataat tggcaattat cagctggaca
    11881 gcaaaggatc gaactataac ttctgtccgg ctaataactg tctggcattc acggtgggaa
    11941 acaacataca gattctttca ccggagaatc agacgagcat tgttacacgt gaaacaaaaa
    12001 atggaatcgt atgcggacag gcagtccatc aacgtgaatt cggcatcagc aaaggactgt
    12061 tctggtcacc ggcaggttcc gccctggctt tctaccggat ggacgagagc atggtcacag
    12121 actatcctat cgtcaatatc gacgcccgcc aggcaaaagc cgaaccggtt aaatatccga
    12181 tggccggcat gaagagccat gaggtaacag tcggtgtgta caacctctcg acaggcgaaa
    12241 ccgtctggct ggaaaccgga accccgaaag aaaagttcct taccaacatc gcctggagcc
    12301 cggacgaaaa gagcatctat attgccgaac tgaaccgcga acagaatgaa atgaacctgg
    12361 ttcgctattc cgccctgacc ggcaagaaag aagccgtcct tttcacagaa acaaacgagc
    12421 attacgttga accgcaatat ccggtactct tcctcccgaa cgatcccggc aaattcatct
    12481 ggcaaagcca gaaagacgga tacaaccacc tgtatctgta tgacaccacc ggcaaacaac
    12541 taaagcaact gacacaggga gaatgggtag tcacccaggt aatcggtttc gatgccaaag
    12601 gcgagaacct gtttatcact tccacccaac cgcacatacg gagttcgttc aattacggca
    12661 ctccgatgaa tgtaaacggc tggaagctga atctaaagaa gggggagaca tccctgctga
    12721 caccgaatgc cgccctggaa agtgtgcata acctttcggt cagcgcctcc ggcaaatatg
    12781 cgatcgacag ttacgacgct ccgaaaatcc cgcgcatcat caacctgatc cggaccaaag
    12841 acggcaagga gatcaaaaac ctcctgaccg cccgggaccc atacaaaggc tacacactgc
    12901 cggaaataga agctggcacc ataaaatctg ccgacggtac aaccgacctg catttccgcc
    12961 tagtcaaacc tgtcggactg gatgagaaca agaaataccc gaccatcgtc tacgtctacg
    13021 gcggccccca ctcacaactg gtaacgggcg gctggcagaa cggcgtaaga ggctgggata
    13081 tctatatggc acaacgcggc tacgtggttt tcacggtcga caaccgcggc acatctaacc
    13141 ggggattcgc tttcgaaagc gtgatccacc gcaacctggg tgtcaacgag atggccgacc
    13201 agatgaaagg cgtggaatac ctgaaatcgc ttccttacgt ggatgccgac cgtatcggtg
    13261 tgcacggatg gagctacggc ggcttcatga cgaccaacct gatcctgacg catcccgatg
    13321 ttttcaaagt cggtgttgcc ggcggtccgg tgatcgactg gagcaactac gagatcatgt
    13381 atggagagcg ttatatggac cgtccgcagg ataatccgga agggtataag aacgccaacc
    13441 tgaagctgaa ggcaggcaac ctgaaaggcc atctcctcca gatacacggc gacatcgacc
    13501 cggtagtagt atggcaacat agcctgggct tcctgaaagc ctgcgtggat gcagatacct
    13561 atcccgatta tttcgtctac ccccgccacg agcacaacgt gacaggcaaa gaccgcccgc
    13621 atctctacga gaagataaca cggtatttcg atgactactt gaagaatacg aacaaagagt
    13681 aactgtttcc cctcttgaga ggggaaacag ttaccatcag ataatataat aaacataac
//
