LOCUS       c00006_gnlPro..        16904 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNCAIGMN_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:26:06
            Original ID  :: gnl|Prokka|HNCAIGMN_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16904
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16904
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3928:6904]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3929..6904
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16904
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16904
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(19..3711)
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MRNILFTVLFIGILSLIASPISLASKSLHKANMINLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVDTDNKLYRQHVDGKGKEFLFDLPEMTKQYGNIIKICTFQSNVYIVFRNGNILDL
                     SQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIRMFYDKPDLFGSILLKDLPINIQNP
                     IRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKMIPQSAITHFTTADGLSSNRVYCFQ
                     KSEYHPCIWIGTEGPGLTYYSYKEKRIKTIPQREDTTPLRYVHSICEVDDSTLWLATTG
                     NGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEIQSMVYDNDSTLFLGSRGGYGVIRF
                     NIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFYAGASSGLTRIKFRGGKMRLRQFDK
                     SDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRNNFFHNYHQPYFSVTEFSDDAYWKC
                     PYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFELQMDKQILPLYKDISRNGVTVPAD
                     VQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKLQKTNKVTFMNLPYGEYLLKVRYRN
                     DVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGTVLLIIATYRIHHQILKKQKQIADK
                     IKEEQKEKLYESKLNFFTHITHELCTPLTLINGVENYIQAYAATSKDKTLEKYTSVLRE
                     NVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSSLLRTQFEWFYPLSEQHQIQFKIDA
                     PKELYWNTDSVYFKKILANLISNAFKYTEDGGTVRISLHEEENFLVLKVYNTGKGIEEA
                     DMQNIFDRYRILGTMDNDDNRQNTARNGLGLFICHSLVQSLGGKIDIESEVGQYAEFTV
                     TLPFGIVEESSDDTIDEDIPVSLPSPNTDIQKPQISHTAQKETEDKPMILVIDDHKDIV
                     WLITETLSSEYQVQEAYNAEEALEFLKQYTPSLIITDIMMPNIDGLELISLIKENRYTR
                     HIPLIIVSAKISDQEQAAGLNIGADAYLTKPFSPTVLLSVVNRLMTNQRELKEYFLNSA
                     TLLQI"
     CDS             3929..6169
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_2"
                     /sec_met_domain="Gly_radical (E-value: 4.7e-45, bitscore:
                     145.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.7e-281, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREMQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             6170..6904
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.1e-32, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             7031..7681
                     /locus_tag="ctg6_4"
                     /transl_table=11
                     /translation="LLYATNIYFCKEIKNDIDQKMMNSMKTPQEIAEMISKRFYPLPDA
                     DLDSLASIIESSKAAKGELLLDNGQISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNI
                     VICIASTFQREPTRLLIEALEPTVYHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQ
                     EKADSWRFESARKRYLRFQQEYPEAAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             7789..9069
                     /locus_tag="ctg6_5"
                     /transl_table=11
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGEN
                     EALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTKSK
                     LGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQE
                     FMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDALNSII
                     AAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLEKLINE
                     YPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCGNSILIK
                     VNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSD
                     RMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             9290..9856
                     /locus_tag="ctg6_6"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             9876..11429
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_7"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-47, bitscore:
                     155.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESTLKEQLKGIFAGLNANYTFDISISPAYESRQELLDLLGDVA
                     SCSDKISMQVSDGEGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASAAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIVATGASWRKLNVPGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFKEIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLD
                     "
     CDS             11515..11865
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPFHK
                     TDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIVPF
                     RGRRTLRAPPIF"
     CDS             11912..14221
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQAMGENRLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGG
                     GSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAG
                     LYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGG
                     NLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDP
                     NAYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHI
                     ESAFLQNEWKNKRWSFLIGGRLDKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRA
                     PQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYT
                     SLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRY
                     KEAEKWSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYI
                     PLDKAVETPDFFDMNIKLAYEFPLYKELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIY
                     GPASPRSYFAGVKMSF"
     CDS             complement(14395..15387)
                     /locus_tag="ctg6_10"
                     /transl_table=11
                     /translation="MTDRRTFLRNISLLTLGGIASQKVMASNPTRSIPATDAISSATAG
                     KKMGLQTYSLGQELLQDMPNGLNRLAKAGYTDLEIFGYREDTGKFGDYNPKNTTFIASK
                     DYKKMVDDAGLRISSSHLTPSLREYTKENMPKFDEFWKKATDIHAELGVSCMVQPSLPR
                     IENEDDAKVVSEIFNRAGEITKKAGILWGYHNHSNEFKRVLKAGEKPEQNPNPWAPPKG
                     TYIEELFLKNTDPDKVMFELDVYWAVMGQQDPVEWMENYPNRFKLLHIKDRWIIGDSGM
                     MNFPNIFKKAYEIGILGYYVELEGDKKGRTQFEGVEKSAAYLQAAPFVK"
ORIGIN
        1 gctcaggtac ttaaaaagtt atatttgtaa tagtgttgcg gaattaagga aatactcttt
       61 taattctctt tgatttgtca tcaatcggtt cacgacggat aggagaactg ttggcgagaa
      121 aggcttggtt agataggcat ccgctcctat attaagtcct gccgcttgct cttggtctga
      181 tattttggca gatacgataa taagcgggat atgacgggta tatctatttt ccttgataag
      241 agagatcaat tccaatccgt cgatattagg catcatgata tcggtgatga taagggaggg
      301 agtgtattgc ttgaggaatt ccagagcctc ctccgcatta taagcttcct gaacctgata
      361 ttcggaagag agggtttccg tgattagcca gacgatgtct ttatgatcgt cgataacgag
      421 tatcatcggt ttatcttccg tctctttttg tgccgtatgt gagatttgcg gcttttgtat
      481 atccgtgttt ggggaaggaa gcgatacggg aatatcttcg tctatcgtgt cgtctgagct
      541 ctcctctacg atgccaaaag gtaaggtaac tgtaaattca gcatattggc cgacctcact
      601 ctctatgtcg attttaccac ctaaggattg tacgaggctg tggcagataa ataagccgag
      661 gccattccgt gccgtatttt gcctgttatc gtcgttatcc atcgtgccaa ggatacgata
      721 tcggtcgaaa atattttgca tgtctgcctc ctcgattcct ttgccggtgt tgtaaacttt
      781 aaggacgagg aagttctcct cctcatgtaa ggagatacga accgtgcccc cgtcttccgt
      841 atacttaaat gcgttggaaa tcagatttgc taggatcttc ttgaaataga cggaatccgt
      901 attccaataa agctctttgg gagcatcgat cttgaattgg atttggtgtt gctcggatag
      961 tgggtaaaac cattcgaatt gagttcgcaa aagagaggat acggatactc ttcggatgtg
     1021 cgtatgactg aatccagcgt cttccgcttt ccggaaatca aggatttctt ggataagccc
     1081 gttcagttcc tctacatttt cccggaggac tgaagtgtat ttttctaatg tcttgtcttt
     1141 tgaggtggcg gcataggctt ggatataatt ctccacgcca ttgatcaagg taagcggggt
     1201 gcatagctca tgcgtaatgt gggtaaagaa attcagcttg gactcgtata gcttctcttt
     1261 ttgctcctcc ttgatcttgt ctgcgatctg cttctgtttc tttagtattt ggtgatggat
     1321 acgataggtg gcgatgatga gcaaaaccgt accgataaaa agatacgtga aaatggctaa
     1381 cgagcttaga taaataggag gtaatacctt gataggtaga gtgtattctt ttgctgacga
     1441 atcaatgaca tcgttgcgat aacggacttt cagcaaatat tccccgtacg gtaggttcat
     1501 gaaagttacc ttgtttgtct tttgcaattt ttcccaagag gaattatagt tgaccaactg
     1561 atacgaatac tcgtaattct ccccgttgat gtaatccgga gcgacgaacg caatcgttaa
     1621 cgattgcaca tcagccggaa ccgttacacc gttccggctg atgtccttat ataatggaag
     1681 gatttgttta tccatttgca actcgaagaa acttaattcg ggttgatagg tatgctccgg
     1741 ctccgtttgt ttatttaccc agactaatcc gttgatgcct ccaaagaata aacgctcgga
     1801 gtatgggcat ttccaataag cgtcatcaga gaattccgtg acgctaaagt aaggctgatg
     1861 ataattatgg aaaaagttgt tccggggatt atatttggtg agacctttat tggtactaag
     1921 ccagatacag ctatcgttcc cctcatggat accatggatc atgtcgttta cgatcccgtc
     1981 gcttttatcg aattggcgta aacgcatctt tccccctctg aatttaatcc gggtgagacc
     2041 ggagctggcg cctgcataaa acgtggaatc ttcggtctgg catacggaaa gcacatctcc
     2101 aatggccggg tttcttaaat tgttggtttg caggaattca tatccttgat tgaaaatatt
     2161 gaaacgaatg actccgtaac cgccacggct cccgaggaac agggtagagt cgttgtcata
     2221 taccatcgat tggatttctt tacagatgtt ctttccgttt tttaacggga aggtttgtac
     2281 cttcccgatt gtaggtacgg ctttatctat atgtaaggta accttttgca atccgttacc
     2341 cgttgtcgct agccataatg tggaatcatc tacctcgcaa atagagtgga catagcgtag
     2401 aggggtggtg tcttctcgtt gcggtatcgt ttttattcgt ttctctttat acgaataata
     2461 ggtcagtccc gggccttccg tgccaatcca gatacatgga tggtactcgc ttttttggaa
     2521 gcaatacaca cggttgctgg ataggccgtc ggcggtggta aaatgcgtga tagcgctttg
     2581 tgggatcatc tttttgttat ggtaagtgtc atacgcttgt atccggacaa taccgtctcc
     2641 ttttgtcccg agccaaaggg attgatcatc gtctgtatat aaagaacgta tggggttctg
     2701 tatattaatc ggtaaatcct tgagtaagat agagccgaaa agatcgggtt tgtcataaaa
     2761 catccgtata ccttgcccgt ctgttcccaa ccagagaatc tcctgccttt tatcgttcat
     2821 taggcaaaag ataccgatgc ccatatttat cgtgttttcc ggttggctta ggtctagaat
     2881 attgccgtta cggaaaacga tatacacatt ggattggaag gtgcatatct tgatgatgtt
     2941 accatattgt tttgtcattt caggcagatc gaacaggaat tctttcccct ttccgtctac
     3001 atgctgtcga tataatttat tgtcggtatc tactatgaaa atatgattat tctcgtaaaa
     3061 tgcggataag atcggtttat tatggaattg gcgttcttcc gatagcaaat taaaagtagt
     3121 atcggagaaa tccggagtca actttttcag tatgcccgag gctaataata aataaaaatg
     3181 tccgtccgtc ccggcgaata aggtacgtac ggtttgaggg cctactcctt ctctcggcag
     3241 gtcccggaac ccatcgctag atggggtgta gcaagagatt ctgttttcct tacaaatagc
     3301 gagcgtgatg ccggatgaat cggaggccaa tagatcgcat tccatgtatc cggggaaaga
     3361 ctcggtgact ttccgttctt ttagtgagaa tttattgata cctaaagagg ttgatatcca
     3421 taaaaagccg ggttctgcgt cggatatttt gtgaatgata ttactacaaa gagagttttt
     3481 gttatttaat tcgaaacgat atacatacgt atcttttccg ttgtataagt taagtccgtc
     3541 gtaagtcccg atccacaaat agccatccgg atcttgatgc atgcaaataa tggcattgtt
     3601 cgacaaatta atcatatttg ccttatgcaa agatttagac gcgagtgaga taggagatgc
     3661 gattaaagat agtattccta taaataaaac ggtaaacagg atatttctca tgtgtttgat
     3721 ccagattaac ttttacgttc tgtaggcaaa gatagtgaat aaaatggaga cttcgtgcaa
     3781 agcatcgcat tactatcccg tttcttcttg tatattttta atacctattt atagggattt
     3841 tagaggggtg tcgcaaatgt tacaggaaca tgaggataaa agttttacct ttgcggcggt
     3901 aaaaatgtgg tattagataa gattgtttat gaaatttgag aatgagtgct gggatcactt
     3961 taagggtgag acctggaaaa gagagatcaa tgtaagagat tttatccaga gtaactatac
     4021 gccttatgaa ggggatgatt cctttttagt cgcttcttcc gagaagaccc gtaaggtctg
     4081 gaacaagctg accgagatgt ttaaggtcga gagggaaaag ggagtttatg acgccgagac
     4141 aaaattacct caagggatcg atgtatatgg cccgggctat attgataagg agaatgaggt
     4201 tatcgttggg ttacaaaccg atgctccgct gaaacgtggt atcttcccga agggcggtat
     4261 ccgtatggtc gagaatagct tggaagctta tggttatcat ttggacccga tgacgaaaga
     4321 gatcttcacg aagtaccgta aaactcataa cgagggcgtt ttctccgcat atacggaaga
     4381 gatgattgcc gcacgtcgtt cggctattat caccggtctg cccgacgcgt atggtagagg
     4441 acgtattatt ggtgactatc gtcgtgtcgc tttatatggt acggcaatct tgatcgagga
     4501 gaaaaagcgt ttcttgaatc gtttggatat ccaagagatc acggaagaga tcatccagag
     4561 ccgtgaggag atttccgaac agatcaaggc tttgaaagcg ttcgagaaaa tgtgcgctag
     4621 ctatggcttt gatgtgactc gtccggcaca aaacgctcgt gaggcggttc agtttgtgta
     4681 cttagcttat ctggcggcgg taaaagacca agatggcgcg gcgatgtcta tcggacgtac
     4741 ttctacgttt ttggatattt atatcgagaa agacatccgt gagggtaagt tgaccgaaga
     4801 ggaggcgcaa gaattggtag accagctgat catcaagttg cgtatcgttc gtttcttacg
     4861 tacgccggaa tacaatgatt tgttctccgg tgatccggtt tgggtaacag agtccttggg
     4921 cggccaagga gtggatggcc gttctttggt aacaagaact tcctatcgtt atctccatac
     4981 attatataat ctaggtccgg caccagaacc caatttgacg gttctgtggt ttaagaacgc
     5041 tcccgagaac tggaaacgtt tctgtgccaa ggtctctatc gatacgtcgg ctatccaata
     5101 tgagaacgac gatttgatgc gtccggatta tggagatgat tatggtatcg cttgttgcgt
     5161 ttctcctatg aagatcggta agcagatgca gttcttcgga gcccgtgcga atttggcgaa
     5221 atgtttatta tatgcgatca acggaggacg ggatgagcgc agcggcgtac aggtagcccc
     5281 gatgttcgag ccggttcgcg gcgagtatct ggaatacgat gaggtgatgg ctaagtatga
     5341 gcaaatgatg cgctggttgg cgaaagtgta tgtgaacgcc ttgaagataa tccattatat
     5401 gcatgataaa tacgcgtatg aggcattcga gatgtcgctt cacgatgggg atgtagagcg
     5461 tatccgtgcg acaggtatcg ccggtctttc tatcgttgcc gattcgttgg ctgctatccg
     5521 tgatacgaaa gtacgtgtga tccgtgacga gcgtggcttg gcggttgatt tcgaacgtga
     5581 gggcgaatat gttcctttcg gtaataacga tgatcgtacg gatagtatcg ctgtagagat
     5641 caccgagaag ttcatggaat atttgcgtca gcacgagacc tatcgccatg cgaaacctac
     5701 gcagtccatc cttacgatca cctctaatgt ggtatatggt aagaagactg gtacgacacc
     5761 ggatggccgt atcggtggaa ctcctttcgc tccgggcgcg aaccctatga acggtcgtga
     5821 tacgaaaggt gctatcgctg cgctagcttc ggtagcgaag cttccattcc agcatgcgca
     5881 cgacggcatc tcttatactt tcgctgtttc tccggctacg ttgggaaagg agcgtgaaat
     5941 gcagatcaat aatctggtta gcttattgga tggctatttt actccggatg gaggtcagca
     6001 tctgaatgtt aacgtatttg ataaggattt gttgatcgac gctatggaac atcccgagaa
     6061 atatccgcaa cttacgatcc gtgtatccgg atatgcggta aacttcgtga aactgactcg
     6121 tgaacaacag ttggatgtta tttcaagaac cattaaccat tcactgtaag tgataaaagg
     6181 taagatacat tcattagaga gtttcgggac cgtagatggt cccggaattc gctttgtcgt
     6241 ttttatgcag ggctgcccgt tgcgttgcct gtattgccat aacccggata cttggaaccc
     6301 gaaagggaag gtgaaatatc agatgactcc cggcgagcta ttgacggaag tcttacggta
     6361 taagagtttt atcgcccgtg ggggggtgac tgttaccggt ggggaacctt tattgcaacc
     6421 tgagtttctg aaagagtttt tccgtttgtg ccaagagcaa ggtcttcaca cagctttgga
     6481 cacatctggt ttcgtatgta cctcaaaagc ttgggaagtc ttggattatg cggacttagt
     6541 gttattggac atcaaaacct taaacccgga tttacatccg ttactggcgg gtgtcaagca
     6601 ggataatacg cttctgttct tggatgaatt ggagagacgt ggcatagata cttggattcg
     6661 ccatgttatt gtccccggat atacggataa tgacgagtgg ctggaggcgt tagctcggta
     6721 tgtcagttca tataaagtgg ttcgcaaagt ggaattattg ccttatcata cgatgggaac
     6781 ctataaatat gagcaattag gtctcgatta tccgttaaag ggggtggaac ccttatcaaa
     6841 agaacgttta gataatgcga aagcgatatt ctctcgctac aaaccagaaa ataacaaggc
     6901 ctgatctctc gatcaagcct tgcgattatg caacagctaa tcagggaaaa caatctaatc
     6961 cgattagctt ttaaacgata gtaataattt tttgcctaga ctaaccttga ctatttaata
     7021 tgtgtttgtt ttgttatatg caacaaatat ctatttttgt aaggagataa aaaatgatat
     7081 agatcagaaa atgatgaata gtatgaagac accacaagaa atagccgaaa tgatatccaa
     7141 acgtttttat ccattacccg atgcggattt ggattctctg gcctcgatca tagaatcaag
     7201 taaggctgcg aaaggagaat tattgttgga taacggacaa atatctaaat atttatatta
     7261 tgtggaatcg ggattattac gccagtttta ctataagaat aaacgtgata ttaccgagca
     7321 tttctcctgt gagggaaata tcgttatttg tatagccagc acattccaaa gagaaccgac
     7381 gcgtttatta atcgaggcat tggaaccgac ggtttatcac cggatctctt tttcggaatt
     7441 tagcgattta ttgaaaacat ctttagctat taatagattg taccagaaaa tactggagtg
     7501 ggctttgatg ctttcgcaag agaaagcgga ctcttggcgt tttgagtcgg caagaaaacg
     7561 ttatctgcgt tttcaacagg aatatccgga agcagcgaaa cgtgcttctg tcaatcatat
     7621 cgcctcgtat ttattgatga cacccgaatc tttgagccgg gtgcgggcgg gagtgttgta
     7681 gtctctacct acattcaggt attattgagg tgaaaatagc aatttgtggt gatttcacgg
     7741 ttcaagtaat ccatctatat ttgcgtcagt ttaaaaaacg tagaagcaat gaaaatagaa
     7801 aagattacag gacgtgagat cctagattca agaggtaacc cgacagtaga ggttgatatt
     7861 ttactagagt ccggcgttat gggccgtgcg tctgtgcctt ccggtgcgtc caccggcgag
     7921 aacgaggctt tggagttgcg tgatggcgat aagaagcgtt atggtggtaa aggcgtattg
     7981 aaagcggttg agaatatcaa tacgattatc gctccggcat tgaaggggat gtctgccttg
     8041 gatcagatag gtatcgatca tgcgatgttg gctttggacg gtacgaaaac taaatcgaaa
     8101 ctaggtgcga acgctatcct tggcgtttct ttagctgtag cgaaagctgc cgcaaattat
     8161 ttggatattc ctttatatag atatattggt ggaacgaata cctacgtgat gcctgttccg
     8221 atgatgaata taatcaatgg cggttcgcat agcgacgctc cgatcgcttt ccaagagttt
     8281 atgattcgtc cggtaggtgc cgcttctttc aaggaaggct tacgtatggg cgctgaggta
     8341 ttccatgcgt tgaaaaaggt attgcacgat cgtgggttaa gtaccgctgt tggtgatgag
     8401 ggtggtttcg ccccgaattt ggaaggtacg gaagatgcct tgaactcaat tatcgccgct
     8461 atcaaggcgg ctggttatga accgggcaag gatgtgatga tcggtatgga ttgcgcttct
     8521 tctgagtttt ataaggatgg aatctacgat tacacgaagt ttgaaggaga aaaaggagtg
     8581 aaacgtactt ccgacgaaca agtggattat ctggaaaagc tgatcaacga atacccgatc
     8641 gattccattg aggatggtat gagtgagaat gattgggctg gttggaagaa actgacagat
     8701 cgtattggta accattgcca attagtcgga gatgatttgt tcgtgacaaa tgtagagttc
     8761 ctttcaaggg gtattaaaga aggttgcggt aactcaatct tgatcaaggt aaatcagatc
     8821 ggttccttga cggagacact gaacgctatc gagatggctc accgtcatgg atacacgacc
     8881 gttacttcac accgttccgg tgagacggaa gacgctacga tcgccgatat cgctgtcgct
     8941 accaatagcg gacagatcaa gacgggatca ttaagtcgtt cggaccgtat ggctaaatat
     9001 aaccagctgc ttcgtatcga ggaggaattg ggagaccgtg ccgtatacgg atacaaaaga
     9061 atcaattaag tatataaagt aaattataat cgctaattat gtagtaatcc aaaacccaag
     9121 atattgaagg gcttatccgt gaggataggc cctttttatt gattgataaa gtattatcta
     9181 taacctcata aaatatatcg attagaaaaa ttgttttaat gaataaatat gttatatttt
     9241 tgtatcggaa ataaaaacaa atagtattca tttaaaaata ggaacaagta tggaaccgat
     9301 tattaattct caacttccgg agtttaaagt acaagctttt caaaatggta atttcaagac
     9361 tgtaaccaac gaggacgtct tgggtaagtg ggctatcttt ttcttctacc cggccgattt
     9421 tacatttgtt tgtccaacag agttggtcga tatggctgag aagtatgagc agtttaaatc
     9481 aatgggagta gaaatttact ctgtaagtac agactctcat tttgtacata aagcttggca
     9541 tgacgcttcc gagactatcc gtaagatcca atatccgatg ttggcggatc ccactggagc
     9601 actgagtcgt gcgtttggtg tgatgattga ggaagagggt atggcatacc gtggcacttt
     9661 cttggtaaat ccggaaggaa agatcaaagt ggccgagatt catgataaca atatcggtcg
     9721 tgacgcttcc gagttacttc gtaaagttga agccgctcag tttgtcgctt cacatgatgg
     9781 tgaggtttgt cccgctaaat ggaagaaagg ggaggctacc ttgaaaccta gcattgactt
     9841 ggtagggaaa atctaaataa ttaagagtat agatcgtgtt agaatcaaca ttaaaagaac
     9901 aattgaaagg tatattcgca gggttaaatg cgaattatac ctttgatata tcgatctctc
     9961 ctgcgtatga aagtagacag gaattgttgg atttattagg tgatgttgcc tcttgttcgg
    10021 ataaaatatc tatgcaagta tctgatgggg agggattgga attcattttg ttaaaggatg
    10081 gagcgaaaac ggggattaag tttcgtggag tacctaatgg acacgagttt acttccttac
    10141 tgttggcgat cttgaattca gatgggaaag gcaagaattt tccggacgag agcatttgta
    10201 atcgtgttaa agccttgaat ggcccgatac atctgacgac ctatgtctct ttgacttgta
    10261 cgaattgccc ggatgtggta caggcattaa acgctatgac gactttaaat cctcagatcc
    10321 atcatgagat ggtagatggg gctatcaatc aagcggaagt tgatgccttg aagatacaag
    10381 gcgtcccctc tgtctttgcg gatggaaaac tgatccatgt aggacgtggg gaattcggtg
    10441 aattgttatc gaagctggaa gctcagtatg gaatcaatga gagcctaacg gagaagacgg
    10501 taaaacgata tgacgtggtt gtggtcggtg ggggtccggc tggtgcttct gccgctattt
    10561 attccgcacg aaaggggctg agtgtcgctg tcgtggcgga gcgtatcggc gggcaggtga
    10621 aggagacggt aggaattgag aatctgattt cagttccgga gacaacaggt acccagttgg
    10681 ctgacaatct gcgcttgcat atgcggcaat atccgattga cctgctggag catcgtcgta
    10741 tagagaaggt aacgatagaa ggaaacgaga aggttttatc tacggctgga ggtgagatat
    10801 tcaaggctcc ggcggttatt gtcgctacgg gcgctagctg gcgtaaattg aatgtaccgg
    10861 gtgaggcaga gtatataggg cgtggagtgg ctttttgtcc tcattgcgac ggtccgtttt
    10921 ataagggaaa acatgttgcc gtggttggcg gtggaaattc cggtatcgag gcggctattg
    10981 atttggcggg gatctgttcg aaagtaaccg ttttggagtt tatggatgag ttaaaagcgg
    11041 atcaagtctt gcaagagaaa gcgaagagtt tgccgaatgt cgagatcttt gttagttcac
    11101 aaacaaccga ggtggttgga aatggcgaca aggtaaccgg tatccgtaca aaggatcgta
    11161 agacagggga agagcgtgtt attcatttag acggtatttt tgttcaaatc ggcttagccg
    11221 ctaatagtgg tgtctttaag gagattgtcg aaacaaatcg tcccggtgag atcgtgattg
    11281 acgcacattg ccggacgaat gtcccgggta tttatgcagc gggcgacgtt tccaccgtac
    11341 cctttaagca aatcattatt tctatgggag aaggagccaa agcggccctt tcggcctttg
    11401 aagatcgggt acgtggcgta cttgattgag gaaagtacct acaaataggt aatttttgaa
    11461 cagcgtatct cttttatcgg ttatattact atatttgcga tcgagagaaa agagatggat
    11521 agattaagaa aatatctgag gatattactc cctgcgctgt tcatagccta tttgggatgt
    11581 attattgcgt ttactcacgt tcatattgtc aacggggtaa cgatcgtcca ttctcacccg
    11641 tttcataaaa cggacgatgg tcgtccggac catgaacatg gctacgccga gtttcagttg
    11701 cttcatcagt tatctgtctt gcagataaca ggtgcggctt tcgtcgctat tctgctggcg
    11761 gctttttatt cctttatccg taacttatct ttcgctccgg tctatccgga ctatatcgtt
    11821 cccttccggg gaagacgtac gcttcgtgct cctcccatat tctgatattg tgagattaat
    11881 aacattgtat tacttatcag aataaattaa aatgaataaa tttttcatct ttatactatg
    11941 cctgtgctgt gccctaacgg tagctcaggc catgggagag aaccgtctaa acgactcaga
    12001 cgcaaatgtt ttcggacatg tattggataa gaaaacaggg gaacatcttc cctttatcaa
    12061 cgtattgtta aaaggtacca cgatcggtac gaccaccgat aactcgggac attatttcct
    12121 gaagaatctg ccggaaggta aatttacgct agaatataaa gcgctcgggt ataagactat
    12181 ctctaaagaa gtgaccctaa agaaaggaaa aaccttagag attaatgtag aactggaaga
    12241 agaccagatc gccttggatg gcgtggtggt atctgcgaat cgtgcggaaa cttcccgccg
    12301 gttggctccc acattagtga atgtattgga tgcgaaggtt tttactacga ccaatgcggt
    12361 gaatttggca cagggactaa atttccaacc gggtgtacgg gtagagacga attgccagaa
    12421 ttgcggtttc cagcaagtcc ggatcaatgg attagacgga ccttataccc aaatactgat
    12481 tgattcacgt cccatattca gcgctttatc cggcgtatat gggcttgagc aaataccggc
    12541 gaatatgatc gagcgggtag aggtgatgcg aggaggggga tcggcactgt tcggctcgtc
    12601 cgctatcgcc gggacaatta atatcatcac gaaggagccc ttgagaaatt ccggggaatt
    12661 gtcgcatacg ttaacctcga ttggcgggac atctgctttc gataataata cgaccctaaa
    12721 tgcctctttg gtatcggaaa atgggaaagc gggcttatat ctttttggcc agaaccgtca
    12781 tcgttccggt tttgatcagg atggagatgg ttttacggag ttgcctaaat tgaagaatca
    12841 aacggttggt ttccgttcgt acctgaaaac gagtacttat agtaaattga cattcgagta
    12901 tcatcatatg aatgaatacc gcaggggagg aaatctgttg gatcgtccgc ctcatgaagc
    12961 ggatatcgcc gaacagttgg agcattcgat tgatggagga ggtctgaaat tcgatctttt
    13021 ctccaaggat tacaaacata aatggagtgt tttcacttct gcccagaata cagaccggga
    13081 tagttattac gggacgaacc aagatccgaa cgcttacggc aagactacgg acctgacggt
    13141 tatggccggt acgcaatatg cttatagttt tgataaattc ttgtttatgc catcggattt
    13201 gactgccggt ttggagtata gtttcgatca tttgaaagac gagatgatcg ggtataatcg
    13261 ctttacgaat cagaaggtgc atatcgagag cgcatttttg cagaatgagt ggaaaaataa
    13321 gcgatggagc ttcttgattg gcggtcgttt ggataaacat aatatgatgg atcatgtaat
    13381 attcagccct cgtgcgaata tccgttttaa cccgacggaa gatatcaata tccgggctag
    13441 ttattccagt ggtttccgtg ccccgcaagc gttcgatgag gatatgcata tctcggcggt
    13501 cggcggagag gtcgctatga tccagcgtgc gaaagattta tccgaggaga aatcgcagag
    13561 cttgagtgct tcggtcgatt tttaccatcg ttttaagaat ggtatccagt tgaacttctt
    13621 ggtggaaggt ttttacacca gcttaagtga tgtgtttgtc ttggaagata tcgggaaaga
    13681 tgagcaaggc aatctgatta aggaacgtcg taacggttcc ggggcgaaag tgatgggatt
    13741 aaccttggaa ggaaagtcgg tgttaacttc atggctatct ttgcaagcgg gcgctacttt
    13801 ccagcgaagc cgttataaag aggccgagaa atggagcgat gacgagaatg tgccagccga
    13861 gacaaagatg ttccgtacgc cggatatcta tggttatttt acggctactc tcacgccttt
    13921 caaacgtttc acggcttccc tgtcgggaac ctatacggga agtatgttgg tgcagcattt
    13981 ggcgggatat atacctttgg ataaggcggt ggagactccg gatttctttg atatgaatat
    14041 caagcttgcg tatgagttcc cgctttacaa agagctgaaa ctagaagtaa atgggggcgt
    14101 gcagaatctg ttcaacgctt accaatccga ctttgaccaa ggtaagaacc gggattcctc
    14161 ctatatctat ggcccggcta gcccgagaag ttattttgcc ggtgtaaaga tgagctttta
    14221 atcatgtaat gccctttgaa aaaacatgta cgtgtttcgt gaaaaacacg tacgtgtttc
    14281 cgaaaaaaga cgtacgtgtt tttttgaagg caaaataaat aaaaagacag tgttcccaag
    14341 cgtatgatcg ccctacggaa acactgtctt ttttatggga taaatcggga tgttttattt
    14401 aacgaacgga gcggcttgca aataggcggc gctcttctct acgccctcga actgggtacg
    14461 gccttttttg tcaccttcca gttccacgta gtagccgagg ataccgatct cgtacgcttt
    14521 tttgaatata ttcgggaaat tcatcatacc ggaatcaccg atgatccaac gatccttgat
    14581 gtgcaataac ttaaaacgat tcggataatt ctccatccat tccacgggat cttgctgccc
    14641 cataacggcc caatatacat ccaactcgaa cataacctta tccggatcgg tattttttag
    14701 gaataactcc tcgatataag tacctttagg aggtgcccac ggattcgggt tctgttccgg
    14761 tttctcgccg gctttcaata cccgtttgaa ctcattgcta tgattatggt aaccccatag
    14821 gattccggct ttcttcgtga tctctccggc acggttgaag atctccgata ctactttggc
    14881 gtcatcctcg ttttcgatac ggggtaaact cggttgtacc atacaactaa cacctagctc
    14941 ggcatggata tcggttgcct ttttccagaa ctcgtcgaat ttgggcatat tctctttcgt
    15001 gtactcacga agagaagggg tcaggtgtga gctactgatt ctcaaaccgg catcatccac
    15061 cattttctta taatccttgg aggcgatgaa tgtcgtattt ttaggattat aatcaccgaa
    15121 tttaccagtg tcttccctat atccgaaaat ctccagatcg gtatatcccg cttttgccaa
    15181 tcggttcaat ccgttaggca tatcttgcag taactcctgt ccgagcgaat aggtttgcaa
    15241 tcccatcttt ttcccggcgg ttgccgagga tatcgcatcc gtggcgggta tggatctggt
    15301 gggatttgaa gccattactt tttggctggc tatgccccct aaagtaagta atgaaatgtt
    15361 tctcaaaaat gttcttctgt ctgtcatggt gataaagaat taaaattaaa catctgtttc
    15421 tcgcaaatat agttaacctt tttgaagttt attaagaaaa tgtctctcaa aaacttgcga
    15481 ttgggtttaa atagatttaa aatttgacat aactcaattt tacgaactta ctccatacat
    15541 ccaattacct gaataagggg attgtttggt atacctccgt ggatttttaa tgtgatttta
    15601 cccattctta ggtattgtgg ggctgtagtc tctgatcgta actttgcaac gttttaaata
    15661 acataattga ttaaatgatg atgaagaaaa tcagagggct tttcctctcc tttttactgt
    15721 tgcttatttc catctcggct ttttctcaac ataaaacaat gatatcgggt aaagtcctgt
    15781 ccacggaaaa aacaaccgtg gatttcgcta ccgtttatct aaaaggtacg aattacggcg
    15841 ggactacgaa tgaggaaggt atctatcatc ttcaagctcc cgcgggagaa tatacattag
    15901 tagtatcggc tatcggatat aagacggtag agaaacccgt gaaactgatg cgtggggaac
    15961 ggacgaagat gaatgtggta atcagccctc aagctacgga gttggatgag gtggttgtcg
    16021 tttctaatgg cgtgacccgg ctcaagcgtt ctgcgttcaa tgccgtggcc ctcgatacga
    16081 aagccttgca aaattcaacc cagaacttga gtgaagcctt ggctcaagcg cccggaatga
    16141 agatccggga gtccggcggt gtcggctcgg atatgcaact gatgatggat ggatttaccg
    16201 gcaagcatat caagatcttt atcgatgggg ttccgcaaga aggtgtcggc agttctttcg
    16261 gactgaataa cattccggtg aattatgccg agcgtataga ggtctataag ggtgtggtac
    16321 cggtgggttt cggaacagac gctatcggag gtgttatcaa tatcatcacc aagaagaacc
    16381 ggaacaaatg gtttttggat gcttcttatt catacgggtc tttcaatacg cataaatctt
    16441 atgtgaactt cggacaaact ttccggagcg gactcacgta tgagatcaac gttttccaga
    16501 attattcgga taataattac tatgtggata ctccggtgaa ggactttacg accggagcga
    16561 tcaataagaa aaagatcgag catgtgaagc gttttcatga tacgtatcat aacgaggccg
    16621 ttatcgggaa aataggtttc gtggataaga aatgggcgga tcgtttgatg tttgggttta
    16681 cctattcaca tatgtataaa gatatacaga cgggcgtgcg tcaagaagtg gtgtttggcg
    16741 gcaaatatcg gaagggatac tcgatcatgc cgtcgttgga ctatcgcaag cgtgatttct
    16801 tcgttagggg cttggatgtg gtattgacgg cgaattataa taagaacatg acgaacaatg
    16861 tagatacctc ttcctatgaa tataattggc gtggcgagat gcgt
//
