LOCUS       gnlProkkaFODKBJLG_154  10494 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FODKBJLG_154.
ACCESSION   gnlProkkaFODKBJLG_154
VERSION     gnlProkkaFODKBJLG_154
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 00:16:39
            Original ID  :: gnl|Prokka|FODKBJLG_154
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10494
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10494
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1761:6035]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1762..6035
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10494
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10494
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..364)
                     /locus_tag="ctg154_1"
                     /transl_table=11
                     /translation="MFVEKIRIRILLVRWIKTIFHISDLNLFLRDVRLYSSKLVYCKKF
                     TVVDLVNLMCEMGMKPGSTIVIHCAMKQFYNFSGTAEELIDAIIEKLGPEGTLCMPSYP
                     FDKKNENILFDVIKSPT"
     CDS             complement(367..1731)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg154_2"
                     /sec_met_domain="Polysacc_synt (E-value: 1.9e-15, bitscore:
                     46.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVFNSNKFFCWINQALITCVSRIICVIETLVPSKFSDKIRILR
                     SHEVVFYNVIGLTFFNSLGGLLTILTQVKLANVMGASHYGVYSYCLAIGEVGAMVVRYG
                     RHKTMVRDLIQYPVRNLQLISSTFIIGVINFLIFLGLVLVFHQDIDIQISVGTVLLICG
                     ACLISLDFQPVYESLNAMSWHSMYNLFQKLIFVIILWGIMLSPFTLSLNVLGIVFFFSW
                     ILVIVWQYKEITSFFHLKIISTCEWSKLFKLYRENFVVAFSCLFGIAFGPIIRIVLNNY
                     CNSREVGVFSAGLQILLIAQFILNQIGRIGNPMMAIIGKDNCSMKQRRLFVYRYLFIML
                     SSTLPFFIPFFFFPSLVVNMFFTEEYADLVIMLPILAVYLIALSVGVVYTQFLISMRKD
                     RLYFIIYVLGATLTILCAFLLIPILGILGATLSLCVPHALTCLCYWWFSANLLRK"
     CDS             complement(1762..2871)
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.3e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg154_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_3"
                     /sec_met_domain="Aminotran_5 (E-value: 8.7e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAQYLLFIR"
     aSDomain        complement(1978..2781)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg154_3_Aminotran_5.1"
                     /evalue="6.30E-34"
                     /label="ctg154_3_Aminotran_5.1"
                     /locus_tag="ctg154_3"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             complement(2868..4004)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(4016..5317)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.4e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.1e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(5337..6035)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_6"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(6049..7332)
                     /locus_tag="ctg154_7"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             complement(7329..7814)
                     /locus_tag="ctg154_8"
                     /transl_table=11
                     /translation="MLSLQSEIDSLCAVSHELLHLGLDGEPIYSDRFRQLNTDVYHRCE
                     HLFGSHGRTLEEEASLCIALLTGYNATIYNHGDKEDKIQSVLNRSWDLLDTLPASLLKC
                     RLLVACYAEVFDEELAAEAHAIIDGWKDRELTREECEIVEHLKSLEANPYPYSELHE"
     CDS             complement(7873..8451)
                     /locus_tag="ctg154_9"
                     /transl_table=11
                     /translation="MFHYPGVPQLYPFVNNSINKSWYALRITYSRELAFKEYLDSRGVR
                     NFLPMRYEYVFRGERKIRKLVPVVHNLVFVYATRSEVDEMKSTVGASLPIRYIMDRETR
                     QPITIPEVQMRSFIAVAGNYDEQVVYLDPSVVSMKKGDRVRVTGGIFEGVEGEFVRIKG
                     DRRVVVSIQGVMAVATAFIHPSLIELIKN"
     CDS             9500..9847
                     /locus_tag="ctg154_10"
                     /transl_table=11
                     /translation="MKQKKRPASQTEAMKLRWKKRIVFEKGYTEQCAEWMAERLEALTD
                     HLQYGHAAIAYQKQNGDFRLVKATLIYYEAEFHKKYDPTQIEGAVVYWNVDEQRWTTFQ
                     MENFMEWRPIV"
     CDS             9986..10492
                     /locus_tag="ctg154_11"
                     /transl_table=11
                     /translation="MAIAYDGINYFPVGVNFMEENAMEVIEAKYGIKGSAIVLKLLCKI
                     YKEGYFIHWDEEQCLIFANKAGREVQAAEVQGIIEILFIKGILDRNSYLANGILTSANI
                     QKIWMEATKRRKRDLKALPYLLVNDLTQQETEAPEGENVTISPGNVVHDVAVNAKNACN
                     SGQSKV"
ORIGIN
        1 ctgtaggact ctttataaca tcaaataata tattttcatt cttcttatca aatggataag
       61 aaggcataca taatgtacct tctggtccta atttttcaat aatcgcatca attaactcct
      121 ctgcagtacc tgagaaatta taaaactgct tcatagcaca atgaataacg attgtagatc
      181 ctggcttcat tcccatttca cacattaaat tcactaaatc cacaactgta aattttttac
      241 aataaacaag tttagaacta tataatctaa catcacgcag aaaaagattc aaatccgata
      301 tatgaaatat tgtcttaatc caacgtacca ataagatacg aattcttatt ttttcaacaa
      361 acataactac tttcttaaca agttagcaga aaaccaccaa taacataaac aagttaaagc
      421 atgaggtaca cataaagata aagtagcccc caatatcccc aatataggaa taagaagaaa
      481 agcgcacaaa atagtcaaag tagctcctaa aacatatata ataaaataaa gtcgatcctt
      541 tctcatcgaa atcaaaaatt gagtataaac aactcctaca gacaatgcta tcaaataaac
      601 agctaaaata ggtaacatta taactaagtc agcatattct tcagtaaaaa acatattaac
      661 aactaaagaa ggaaaaaaga aaaatggtat aaaaaaaggc aaagtacttg aaagcattat
      721 aaacaaataa cgatatacaa aaagtctccg ttgcttcata gaacaattat cttttccaat
      781 aattgccatc attgggttac caatacgtcc aatttgattt aatataaact gagcaatcaa
      841 taaaatttgt aaacctgcag agaaaactcc cacttcccgt gaattacaat aattatttaa
      901 aacaatacga ataattggtc caaaagctat tccaaaaaga caactaaatg caactacaaa
      961 attttcacga tacaacttaa ataatttact ccattcacat gtagaaatga ttttcaaatg
     1021 aaaaaacgaa gttatttctt tatattgcca tacaattact agtatccaag aaaagaagaa
     1081 tactattcct aatacattca aagataaagt aaatggagac agcattattc cccacaagat
     1141 aataacaaat atcaatttct gaaacaaatt atacatagaa tgccaactca ttgcgtttaa
     1201 agactcatat acaggttgaa aatccaatga gatcaaacaa gcaccgcata taagcaacac
     1261 tgttcctaca gaaatttgaa tatctatatc ttgatgaaaa acaagaacta gccctaaaaa
     1321 aatcaaaaaa ttaattaccc caataataaa tgtggaagaa ataagttgta aatttctaac
     1381 cggatattgt ataagatctc gtaccattgt tttatgtcgc ccatagcgaa ctaccatagc
     1441 accaacttct ccaatagcta aacaatatga atatacccca taatgagaag ctcccattac
     1501 attggctagc tttacttgtg tcaaaatagt caataatcct cccaacgaat taaagaatgt
     1561 caatcctatt acattataaa acacaacctc atgacttctt aaaatcctta ttttatcact
     1621 aaatttagaa ggaaccaaag tttcaatgac acaaattatc ctactaacgc aagtaattaa
     1681 agcttgattt atccaacaaa aaaatttatt tgaattaaac acaacatcca ttctaaagaa
     1741 acatttcttc caatcaacga cctatcttat aaataggaga tattgtgcct ccctcatcac
     1801 ctcaaagaac ctctcaatat cctccacatc aatctctccc aacgcacaaa gccggaatgt
     1861 attcgttgtg gaaatcttac ccgggtagat cgtaaagcca cgttcatagc agtaatcatg
     1921 aaccttatca aaatcccaga ggggatcatc aggatacaat acagaaacaa caagacccga
     1981 ctgccattca cgtttgatcg catactgaag accaagctct tgcaaacctt tatggatggc
     2041 ttcaaagacc ctcttgtgac gggcgaattt agcctcttca cctactgcaa aatattcatc
     2101 aagagcctga cgggcagcgt aaacggtttg aacaggagga gtaaaatgca tctcacccgt
     2161 cttctcaaag taatcgtatt gtaaatagag gttacaatag taggagcgtt tcggataatc
     2221 ccttgaagca cgtatcaggg attcatcacc tatgataaag gaaagacccg tcatggcctg
     2281 aaggcctttc tgagccgaag ccatacaaaa gtcaacatta tccttcccga tatcaaaagg
     2341 aatcataccc agggaagaag tggtgtcgac aacaaaaacg gcaccgtgcg aatgggctat
     2401 ttttccgatc tcacggatgg ggttcaagat acccgtaccc gtttcatggt gcgtggtata
     2461 gaccaaagcg atgtccggat tgtcggaaag cgtcttttcg attaccgaca ggtcgggaag
     2521 ttcgtaaacg gaaaacttca aatcgatatg gggaagaccg taatattcgc agacttccac
     2581 cgcacgggtg ctgtaggcac cgttattgac aaccagaact ttcttatccg caggaagaag
     2641 agagttcagg cagatatcga tattgatcgt acccgagccg caaaacagga cggccgtatg
     2701 tttggagagg tctccatgcg caacgcggac caggtcgtca cgtaactgtt tcatcatacc
     2761 cgcaaactct ttctcacgcg gacagatatc gggaacaacc tgcgccagct tcaccgtatc
     2821 cgtcgtggtg gcgggacccg gattcaaaag gatctttctt tcgatattca tgaatgcgta
     2881 tcttttaaaa atgccataaa atgctcttta ttctctaccg gagtagtcgt agggcgaccc
     2941 agatcatcac gtgaatcgat ccggacctta atttcaagaa gaaccgggcc ggacaggccg
     3001 gacagcttct caagcgcaca cgaaagccct tccttgtcgg aggcagtcag tacatgcgca
     3061 taaccgcaac ctttcgctat cgaggcgata tccagacgga aaccgagcgt gggttgaccg
     3121 ccgacagatt catgcgcacc gttgttgaaa aggacgtgcc tgtaattctt gggagaaaga
     3181 tcgccgatat tgctgacagc acccatgtgc atgataaagg caccgtcacc gtcaagacag
     3241 tagacacggc ggtcaggctt ctcaagggca atccccaggg caatggaaga actgtgaccc
     3301 atggaaccca cagttaggaa atcccttgcg tgcccctgcc ctttcgattc acggtactcg
     3361 aaaagctcac gggagagctt gcccgtggtg gaaaccacaa tgtcattgtc cccgaggtgg
     3421 tcgacaacct gcattagcgc ctcctcgcgg gacagaggat agtcattcaa ggcttcctga
     3481 cgcaatttat attttccaaa cgtatcttta cggatgacaa tcgcatgggg aatcgaccgg
     3541 ctcttcgccg agacaaccgc gtcatggatc tgcgccaggg cctcgtcttc atccgtatcc
     3601 agaattataa aaggaatttt catggctttc agaagatcaa gggtaacctc gccctgcttc
     3661 ttatgctggg gttcgtcttt tgtgccgggc tcaccgcgcc agccgaccag caaaagaaga
     3721 ggaaggctgt acactttctc gtccgcaagg gacaagaggg gattcaccgt atttcccaga
     3781 ccggagttct gcatataaac caaaggaacg ttgccagaag ccatataata accgcaggca
     3841 atgcccaccg cggaaccttc attggcggcg atgatatgct taccacgcgg agcatgatcc
     3901 gtgatatagg cgcaaatatt cttcaaaagg gaatcgggaa cacccgtaaa gaagtcaaca
     3961 ccgtgatgaa ggaacgtatc gtatatcttt tctacactta ccataaccgt ctgatttatt
     4021 tagtgcccgg aatcaattcc agaatttcct tgataggcat acaaagcgga cggacctcct
     4081 cggcgcgctc gttttcaagg atggtcctgg ccacgttcat catggccggg taagcggcac
     4141 ggagaaggtg gttggcgtaa atgactacgt tggcacccca ttcgtgaagt tcggattcgt
     4201 gcacatggtc ataagtcgtc ggaacaacga caatgggaac atgggcgtat tctttgcgga
     4261 aagtccggca gaactcacgg atatcctcac ccgacttatc cttgctgtgg atcatgatgc
     4321 cgtccgcacc cgcctgtaca taggcataag cacgttcgag ggcgtcactc atgggtttgc
     4381 cggcaataag gctttcgata cgcgcaatga tcataaagtc accggtgacc tgggcattct
     4441 tccctgctct gatcttatcg cagaaaccct cgatactatc ctgagtctgg atagcgtcag
     4501 taccaaaaag ggaattcttc ttcagaccga ctttatcttc aatgattacc gcagaaatgc
     4561 cgtgacgttc cagagtgcgc acagtaaaga caaagtgttc gatcttgcca cccgtgtctc
     4621 catcaaaaat aataggcttg gtggtgcatt caaggatatt gttcaggtcc tgtaaacggg
     4681 tggtaaggtc gaccgcttca atatccggtt tacccttact cgtggagtcg gtcaggctgc
     4741 tggaccacat gccgtcaaag acctcgcgct tatcaccctt ctggacttca agattctcaa
     4801 taatcagacc gcaaagaccg tcgtgagcct ccaggatacg gaccacaggc ttggcctgga
     4861 tcaggcggcg gagggactta agacgtacgt caggggtagt cccgatcgcc ttgatatcct
     4921 tgtcgagcga ggaggagttg atgccccggg tataagggat ctcgattacc ttgcccccct
     4981 gggcgttcat cacctcaaaa acctgttcgc gcacctcgcg caacgggccc gttttccagt
     5041 cgtcgccgtg gatgatatag tcaggcttga gtttttccag attcggaaca tagctccagt
     5101 cctcctgggg aacaacctca aaaaccccct tgatattctc aacaacctcc ttacgctgat
     5161 cataggtaag gtaagggagg cgtttgtgtt cggcgatggc cttgtccgtc agcagaccga
     5221 cgatgacatc accgtattta gtagcttcat gaataatatg gatcagcccc ggatgcatga
     5281 tatccgcggt cataccgaca tagattttct tgttcatata tggaaaagat ttgtttttaa
     5341 caatagcgga tgatgtgctc ctcggcatac gaaaggtcgg cttcatcatc gatttcatac
     5401 catttaagac cctccaccct gagcacacgg acaggggaaa cggaacggga catgcggagc
     5461 agttcgtact cgtaacccag tttaggctgg gactccagga tggtcgcata atcggcgcac
     5521 atccggcggt agaaagtatt ggaaagttta tggataccga ccagctcgcc ttttgcctca
     5581 agggcgttct tgtctaccga acaggaagta aggatgtgat tgcggtcata ttccacataa
     5641 tactgatcct ggaacttggt cagagaagag acaagcatca catccgggaa ttcgtcatcc
     5701 agtagcgaga ggatggcctt gcgttcaaaa acaaggtccg attcaagcag caggaaactg
     5761 tcatcgccta tcacgtcacg cgtattgtac agagtgtaca tactgttagt atcggcatag
     5821 cggggactga aacaggtctc tatctggggg aaatccgcct gaagggcttc ataagcctct
     5881 tttttataac ccgtaccgag gatgatacgt tcgataccgc aggaaagaag ggtttcgata
     5941 gagcggataa tcataggttt tccaccaacc tccacaaaac ctttgggcac aagctcggta
     6001 taatgcccga agcgggtacc aagaccggca gccatgatca ttgctgtttt aatcatgaat
     6061 ttcagaggga attaatataa gtgaattcaa ttgttgcttg aaataacagt aaatcgcaaa
     6121 aatcgacagg acagaaacaa atcctgaaaa aagggcagta cgcattagca tgacagtcca
     6181 ggaaatgtca gcagaaacga agttcttgac cataaacaca cccgtagtgc ccagatagcc
     6241 gaaagaatcg gccaaataaa taataaaaac agccgtacta accaccctaa gggaagcaat
     6301 caggcgttct atcaggtaag tgaaaggaat ataccccata tacagaccaa gaccggaaag
     6361 aatcatccac caaataggag aaagaaaacc gtacacataa agcaatgtgg aaaaaaccat
     6421 taaggaaccg cctgtaacgg caatgcaata aatgatatta agagccaaac ggttattacg
     6481 gacaaacaca atcaggaaca tcagtacaag gacaaaaacg gcaatgggaa cctctgtctg
     6541 agtaaagatc attgcacctt caatatggag ctccttccaa atatcggcag cgaaagagtc
     6601 acgaagctca cggaacacgg tcagggcacc gtaaaaaaca accagcatgc agattcccca
     6661 gaagaattgc ctcaaaaatt tacgcctgtc tttaccatcc atcggagcac gtttggtacg
     6721 ctgtatgata tcttgctcat tgggagccgg aatctgattg agaagccagc tgcaaagcaa
     6781 cataacaggg tataccaaca aaccggtggt aaaaggcatc caatattccg acacatgcaa
     6841 attatccatc acgaattgtc ccaaggtttt caccaaaccg gaagagacta tcaaagcaac
     6901 gctcagcccg acattcaata tttcactgat acgacgccct tcgatatagc taaaaatgac
     6961 accccagatc atacccaggg gaagaccgct cagaaaaata gaacacacct tcaaaggaac
     7021 cggaagaagt gcaaaaccca acaaagcaac ttcggaaaaa gtaagcagcc ctattatata
     7081 atagatgcgg tgacccgctt tcatcgaagg cagaatacga acaccgatga acttggaaag
     7141 ggcgtagccg ataatctcag aaaggacata caggattttg acatcgaatc cccaaagaat
     7201 ctcaccttca taaatggctg cggtaaatgg cttacggtag gcataggcac aagtataaac
     7261 cagaaaaatc aaaacgctgg catagagagc caaaacgtaa aggggagaac gggaaagaaa
     7321 ggaacgaatc attcgtgtag ttcgctgtac ggatatggat tagcttccaa gctctttaaa
     7381 tgctccacaa tctcacactc ttccctcgtc aattcccgat ccttccaacc gtctattatt
     7441 gcatgtgcct ccgccgccag ctcttcgtca aagacctcgg cgtaacaagc taccaacaaa
     7501 cggcatttca aaagcgaagc gggaagtgta tccaagagat cccaactacg attgaggacc
     7561 gactggattt tatcttcctt atcaccgtga ttataaatgg tagcattata gccggtcaac
     7621 aaagcgatac aaagagaagc ttcctcttcg agggtacgtc catgtgaacc gaaaagatgc
     7681 tcacaacgat gatacacatc cgtattcaac tgacggaaac ggtcggagta gatgggttcg
     7741 ccatccagac ctaaatggag aagttcgtgc gaaacggcgc acaaagaatc gatttctgat
     7801 tgcaaagaca acatggtgat ttatttacgt attggaatat gcaccacaga gggcacagag
     7861 ttcacagagt ttttaattct ttattaattc gattaaagag ggatgaatga aggccgtggc
     7921 aactgccata accccctgga tggaaaccac cacacggcgg tcacctttga tacggacaaa
     7981 ctcaccctca actccctcga agatgccacc ggtgacacgg acacggtctc cctttttcat
     8041 ggaaacgact gaaggatcca gataaacaac ctgttcatcg taattaccgg caacggcgat
     8101 aaaactacgc atttggactt caggaatggt aataggctga cgggtctcac ggtccatgat
     8161 ataacgaata ggaagagaag ccccgacagt ggatttcatt tcgtcaacct cactgcgagt
     8221 ggcataaaca aaaaccaagt tgtgaacaac aggaaccaat ttacggatct tacgctcacc
     8281 acggaatacg tattcatagc gcatgggaag aaaattcctc actccgcggg agtccaggta
     8341 ttccttaaag gcaagctcac ggctataggt gatacgaagg gcgtaccagg atttattaat
     8401 gctattgttc acaaaaggat ataattgggg gacaccgggg tagtgaaaca ccttccggtc
     8461 aagtttgcta attctgttgt ttgccttgca gcgtatatca tttcatcagg tactccccta
     8521 tcgcaggaga gacagtttga aaaagaagaa cagaaaacga agttttgaaa aaacagggcc
     8581 ttactgatct tacaatctgt aaacgagtct attatgaagc gaaagtgttt caaaagacga
     8641 tcgtcttttg aaacacactt ttttaaagat ccagacaatt aaaatacata taaaagcaga
     8701 cagatattaa agcgtttttt gttagtttat agacatttga ttatcaaata attaaataga
     8761 tcaagccatg aaggaaaaca ttttttttat taaacatttt gcagttatga aaataccctc
     8821 tatctttgcg ttcaattaaa cgatcgttta ttgaaacact cactttttta agaattattt
     8881 catttaatgt cagacaatta agaagagaaa aggtttcatt ttccctttga ttcccacttt
     8941 aattccacat tcatttgccc actgaaagat tactctctac ctttgcaaca tattaacaac
     9001 atttagttat tgattaaata aaaaaatcat gaacaaagaa aatgaattat tacagacagt
     9061 gaacaaaagt gtaaaaaaac gctaacacta aaacacaacc tcctatcaca gaatctatta
     9121 aagaaacaag aggcagaaaa gcaggaacgc agataccggg aattatctcc aacaatgaag
     9181 gagttataaa agcgctgata gaatcctaca tattggacgc aaaagaacaa aatatcaaga
     9241 catgtaaaga ttcgttggca cgctacatag aggaaaaaaa actttttgga aaaataagaa
     9301 atggagtatt caaaccatta gttttcagca caatcagaac ttacgtcaac gagatctgga
     9361 ataagatgga aagaaagaaa aagaaccaag aaggaaagcg ctgaaatacg tacaatgaat
     9421 tttatcaaac cggaatacat tcgatctgac ctatctttgg ggcgataatt tatctattaa
     9481 ccctttaaat catatacgta tgaaacagaa gaaaagaccg gcatcacaaa ctgaagccat
     9541 gaaactgaga tggaaaaaac ggattgtctt tgaaaaagga tataccgaac agtgtgcgga
     9601 atggatggcg gaacgcctgg aagcattgac cgaccacctg caatacgggc acgcagccat
     9661 cgcttatcag aagcagaacg gagacttcag gttggtaaaa gcgacactga tctactatga
     9721 agcggaattc cacaaaaagt atgatcccac acaaatagaa ggcgcagtag tctactggaa
     9781 tgtggatgaa cagcgatgga cgacattcca gatggagaac ttcatggagt ggagaccgat
     9841 cgtatagggc gccaccacag attacacgga ttttcaccga tgaattattt ttattttgag
     9901 aaatcaagtg aagacatctt tgggaatccg gggtaattta tggtgaatgt attattgaaa
     9961 gtacaaacga ctaatctaaa aaacaatggc aatagcatat gacgggatca actatttccc
    10021 ggtgggcgta aacttcatgg aagagaacgc aatggaagtg atagaagcaa aatacggaat
    10081 aaagggttcg gcaatcgtac tgaaactact gtgcaaaata tacaaggagg gatacttcat
    10141 ccattgggat gaagaacagt gcctgatctt tgccaacaag gcgggaagag aggtgcaggc
    10201 cgctgaggta caggggatca ttgagatcct cttcatcaaa gggatattgg acagaaacag
    10261 ttatctggca aacggaatac tgacttcggc aaacatacag aagatatgga tggaggcaac
    10321 aaagcgaaga aaaagggatc tgaaagcatt gccctatctg ctggtgaacg acttgactca
    10381 gcaggaaaca gaagcgccgg aaggtgaaaa tgtaaccatt agtccgggaa atgtagtaca
    10441 tgatgtagcc gttaacgcaa aaaatgcatg caattccgga caaagtaaag taaa
//
