LOCUS       c00059_gnlPro..        13209 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FODKBJLG_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:17:44
            Original ID  :: gnl|Prokka|FODKBJLG_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13209
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13209
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[250:3209]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      251..3209
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13209
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13209
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             251..2479
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_1"
                     /sec_met_domain="Gly_radical (E-value: 8.9e-47, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2484..3209
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3442..4704)
                     /locus_tag="ctg59_3"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4756..5304)
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5624..6244
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MKIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFV
                     GYLQMGEEKPGYENGKIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIE
                     YQYLGSMNENKKHMLNLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDS
                     IAEQLATAKGIKLRVNTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6349..7347)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="LysR_substrate (E-value: 1.3e-46,
                     bitscore: 149.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.9e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMELKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7417..7890
                     /locus_tag="ctg59_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(7994..8992)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1e-69, bitscore:
                     225.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDINQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9047..10117)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_9"
                     /sec_met_domain="MFS_1 (E-value: 5.4e-12, bitscore: 35.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKTKKYFVVATEIITGLAFALVALSLPLPDFFRCAIALMGIIAL
                     SGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLKDEFGVVH
                     AWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFFQKKHIAF
                     YIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFILGSLLAG
                     YYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYGFGFVGLM
                     LFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVLIATIPAF
                     IVTWLVPFTYPDGKKK"
     CDS             complement(10110..10289)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MLGAYCLLCYGIAVCGPFDGFCPYVFRYGSVECTDCFLDFSHYAS
                     LDIEAFMESVSGNV"
     CDS             complement(10565..11578)
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDATAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPGGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11601..12710)
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 ctacggttaa gtagtgcttt tctcttaaag cgatgcaaag gtacgaatca ttttttaact
       61 tgcaaattat tccgcaaaaa aatattagaa aagtatattt ggaagtaata accgccctct
      121 ggcttctccc cataaatagg tatttttatg ctattcaaca taaaatagga cccttttata
      181 tacctaaacc gaaaaaaggt tgtaaatttg cgcgctctaa aggataacta accactaact
      241 gattaatttt atggaactga ataagacctt taaagatgga ctttggagca aagaaatcaa
      301 tgtaagggat ttcgttagta acaacatcac tccttatgaa ggggatgctt ctttcctgca
      361 aggacctacc gaacgcacca aagctgtctg gaatcactgt ctcaaagctc tcgaagaaga
      421 gagaaacaat aatggtattc gtgcactcga ctacacaact gtatctacta taacctctca
      481 ccctgccggc tacatcgata aagaaaacga actgatcgtc ggactacaga ccgatcaggt
      541 gttaaaacgt gccatcaaac cgtttggcgg aatcaatgtg gttatgaaag cttgccgtga
      601 aaacggagtg gaagtagatg acagagttaa ggatatcttc actcactatc gcaagactca
      661 taatgatggg gtattcgatg tgtataccga agaaattcgt tcgttccgtt cattgggatt
      721 ccttaccgga cttcccgaca actatgcacg cggacgtatc atcggtgatt atcgccgcct
      781 ggctctctat ggtcttgacc gtctgataga agctaaaaaa gaagatctgc ataatctgac
      841 aggtcctatg actgaagccc gcattcgtct tcgtgaagaa gtagccgagc aaatcaaggc
      901 cctgaaagag attaaagtat tgggcgaata ttatggtttg gatttgagcc gaccggcata
      961 taccgcacag gaagctgtac aatgggtgta tatggcttat ctggctgccg taaaagagca
     1021 ggatggtgct gccatgtcac tgggtaatgt atcttcattc ctcgacatct atcttgaata
     1081 tgaattaagc cagggtacga taaccgaaac attcgctcag gaactgatcg accaattcgt
     1141 tatcaaactc cgtatggtac gccacttgcg tatgcagtcg tacaacgata tttttgcggg
     1201 tgatcccaca tgggtgaccg aatctatcgg tggacgtttc aatgacggac gtaccaaagt
     1261 tactaaaact tctttccgct tcttgcagac actttataac ttaggcccgt caccggaacc
     1321 taacatgact gtactatgga gccctgagtt acccgaaggt ttcaaagcat tctgtgcaca
     1381 agtatctatc gacacttctt ccgtacaata cgaaaacgac gacctaatgc gtgaagtccg
     1441 tcaatcggat gactacggaa tcgcttgttg tgtttcatat caggaaatcg gaaagcagat
     1501 tcaattcttc ggcgcacgtg ccaaccttgc caaagccctg ctactggcta tcaacggagg
     1561 acgttgcgaa aatacaggta cagttatggt aaaagacatc cctgtattga ccggtgaaac
     1621 actgaagttc gaagaagtaa tggccaacta taagaaagta ttgatacaaa ttgcacgtgt
     1681 atacaacgaa gcaatgaata tcatacatta catgcacgat aagtattact acgaaaaggc
     1741 gcagatggct ttcgtggata ctgatccccg cattaacctc gcttatggtg tagccggact
     1801 ttcaatcgcc atcgattcac tgtccgccat caaatatgca catgtgaaag cccgtcgcaa
     1861 cgacatcgga ctgacggagg gattcgatat cgaaggtgct ttcccttgtt tcggtaatga
     1921 cgatgaccgt gtagaccact tgggtgtgga cctggtatat ttctttagcg aagaattaaa
     1981 gaaactcccc gtatataaga atgcccgtcc taccctttcg ctgctgacta tcacttcgaa
     2041 cgtaatgtat ggcaagaaga ccggtgccac tcctgacgga cgcgccaaag gcattgcctt
     2101 tgctcccggt gccaacccca tgcacggacg tgataaaaat ggtgcaatcg cctcactgag
     2161 ttctgtagcc aagttgcgtt atcgcgactc acaggatggt atcagcaata cattctcaat
     2221 cgttcccaaa tcattgggag caacacaaga agaccgtatc gacaatctgg tgaccatgat
     2281 ggacggatat tttacaaaag gcgcacacca cctgaacgta aacgtgctga accgggaaat
     2341 gttgcaggat gcgatggaac atcccgaaaa gtatccgcaa ctgactatcc gtgtctcagg
     2401 atatgccgtt aatttcgtga aattgagccg cgaacatcag ttggaagtaa tcagccgcag
     2461 tttccacgaa agaatgtaat tgaatgataa acgtacactc atacgagtca atgggaacat
     2521 tcgacgggcc gggtctccgg ctcgtcgttt tccttcaagg gtgtaacttc cgttgcctct
     2581 attgtgccaa tccggacaca attgaagcca aaggagggac agcaaccgac cctgaggaaa
     2641 tagttcgcat ggccgtcagt cagaaagctt tcttcggtaa aaagggaggt atcacctttt
     2701 ccggcggaga gcctactttt caagcaaaat cgcttatccc actttttaaa agactaaagg
     2761 aagcaggaat ccatatttgc cttgatacca atggcgggct atggaacaat gatgtagagg
     2821 aactattgga attgactgat ctggttttat tagatatcaa agaatttaat ccggaacatc
     2881 atcagtcttt aaccggaaga agcaacgagc agaccctgaa aaccgcagcc tggcttgaaa
     2941 ccaatcataa accattctgg ttgcgatacg tattagtgcc cggctacagt gacttcgaag
     3001 acgatatccg gcagctggga gagcatcttg gaacgtacca gatgattcag cgtgtagaaa
     3061 tattgcctta ccacaccttg ggtgttcaca aatatgaagc aatgaacaaa gaatatatgc
     3121 tgaaaggagt gaaagagaat actccagagc agatagaaaa ggctgagaaa ctattcaggc
     3181 aatatttcca gaccgtacaa gtaaattgac ttatataagt gtcgaaactc gtattcgcca
     3241 cagattacac gaatttacac agataaagat tcattggcca tcaatagatt aagttcactc
     3301 tgcggtgaat tatgacgact gcacttattt ataattttgt aagtcacgat ataaaagtct
     3361 ccctgttctt gccttaattc attacaatac aaggcaagaa cagggagata atgtaaccgg
     3421 catatttttt gccaccctac tttaataagt gaatcgcaat cctgcctgca agttaaagtt
     3481 acaaggcctt tcttttcgga tggtttgtac tttggagcca tcatcaaaga aatacgaaac
     3541 tcccggttcc acatataggc cgacatgatc tgtcgcattg aactgcgctc ccacggcacc
     3601 ggctacagaa aattgcaaag gcttcacatt caccttatca tccgccaact ttccataaac
     3661 acacttttca accattcctc cggcagatac atagagtgta aaatatttct tttccagaaa
     3721 attccagttt ccacgtacag gaatacctat ataatgcaat ttctgactct gcatcttggt
     3781 atccccctgc cgtttgatat cagaagacaa caacgtataa gtcaatcccg tctctacaga
     3841 gaaacctttg ggaagagact tacgtacaga cagtccgaag ctaaccggct gatgatgttc
     3901 ataatccacc acggcagttg tattggactt caggtaagga accccttcct caaatataac
     3961 ttcctgatcg gcaggaatac tcacagctcc attcatgatc gtcatcaagt cgaccctgtt
     4021 agtcatcgga cggggcgcaa aattttcgga accatttgtc ggaagtccac ctccattacc
     4081 gatacccact cccatcgacc atttaccacc acgtttagca gaagagtctc cgataggcaa
     4141 ctgatacttg tctttaccgg acggtcgccg cgcttctttc ctctttggag gctgcgccgt
     4201 cgcactttct tttttctcga ttgcagcaat tgcttcctgt tgcggctcag atctcttttc
     4261 ctccgtcact gcctccggtc gcttctctac cagggaggat acctccggaa caatcaccgg
     4321 atcagtattc tttgccaaat agcccgaaac agggttaata ctcgtcgttc ctaccggctt
     4381 aactggttcg gatacagcta cctgtacatc cggcaaggca ggttccggca atacatccgg
     4441 gttgacagcc agtgaaggag ccgttgcata acggatttca tcagctaccg ggctattcag
     4501 aaaatacaaa ctgacagcag tcgttagcac caataccaca gctgccgcag caaccgccca
     4561 ccggcgatac ggatatattc gtttttcggt tacaggcatc agttcccttt ccagtcgttc
     4621 ccaaccggaa gcaggcatcg gctccgaata atcttcgagc ttatccttga atgctttaat
     4681 ccatttttcg tcttctttca tcattctatt tcatttttga aatccaaggt tcacctcagt
     4741 atctgtaaat acatgtcaac cattggtcac caaccattct ttcactttct ttgccaatac
     4801 actttttgcg cgaaaaagct gtgaggcaga agatttttca ttaatcccca acatctgtgc
     4861 gatttccttg tgcgacttat cttcaaaggt gtataaattg aatacggtac gatatccggc
     4921 ggggagttca ttaataaatt gcatcagcac tttctgtggt attgcttcaa cagccgaagc
     4981 atccggttct tcatacgttt cgggaacttc atccagtgcc gtggtctggt tcatcacgtc
     5041 gttctttctt aagaactgta aagccgtatt caccattaca cgctccatcc atgctctcag
     5101 agagccttca ccccgccagg taaacttgtc gaaggagtcg aaaatcttca ggaaaccgtc
     5161 gtgtaccaag tcttgtgcca tatccctgtc tccggcataa cgaagacaga caccaagcat
     5221 gcgccctgcg tactgctcat aaagttcttt gcgggcacga ttatctccct gcctgcaacg
     5281 ttccgacagc tctaattcat tcattctcct aaacacgtgt ttaccttata aatgcagcaa
     5341 agatagaaat actgcacaga gagaacaact cttttatcac ttttgtttct ttaacatttt
     5401 aggatgcaat atatcatcac ttcctgcatt ttctcaatac aataaagaat aaatctcaat
     5461 ggataaatag gataaaacca acaagaaact tatgaagaaa tttaatttaa taacttttgc
     5521 cgtcatcctg atgttattgc ccattttaca gtcatgtctg gacgatgcca acaacgacga
     5581 gtgggtcact tgtcctccgg gtggaatatt ggccatcggc acaatgaaga ttcccaatgc
     5641 ggacactcca agggactttt tcattgcgtt ggacaatgga gacaatgtac ttccggcaga
     5701 tacggccgat atacgcaaca ggaaatacac tgttgcagaa ggacaaagag tcttcgttgg
     5761 ctatctgcag atgggagaag agaaacctgg atatgagaac ggtaaaatat tcacgataga
     5821 agatatattg acgaaagaga tcatcccact gacggaagct acagcagaca gcattggaga
     5881 cgaccgtatc aacgtcacag cgcatgcact tacgaaagat tatctgacca tcgaatatca
     5941 atatctgggc agcatgaatg aaaataaaaa acacatgctg aacttggtac aaaacgaaat
     6001 aacaggtccc ataaaagatg acggatatat ctatctggag ttccggcata atgcctttaa
     6061 tgactccccc aatcaattgg gttcgagcct tgtttctttc aagctggata gtatagccga
     6121 gcaattggcg acagccaaag gaataaaact ccgtgtgaac accatttatg acaatataca
     6181 gtatgtcaca atagatatca acgaagacaa aaacttaaaa ataaaatcat ttcattctca
     6241 ataaaacaac aagaaacacc tacacaatca ggcaaaacga gtaataattc tgatacataa
     6301 aagaaataag gcggcgatgt ttgtgaaaat atcgccgtcg tttttatatt ataccagaca
     6361 ctgaacggcc tgcagggtaa gcatctcctt gggaaccgcc gcctgaatct cctctttcaa
     6421 aacctgcagc agactggtgc ggatgaagtc tttccgggtc accaggacaa tctgacgggt
     6481 aggccgcggg atagcaaacg gacggaccag ttctttctgc tcttcgctca attgcatcac
     6541 tgccagttcg ggaataaacg taatcccctt accactctcc accatatgca taaaggtttc
     6601 catactaccc agccgatacg ccatttggct gatcttaacc gcttccatct gacaaaaacg
     6661 aaccaactga tcgcggaagc aatgcccttc gtcaagaagc caaagccgtt cccctgtcac
     6721 atcggacgta cgaatcacat cgtgcttgaa caacggttcc ttctttgaga catagcccag
     6781 gaattgctcg taaaataagg tctcttccgt taatgcggca tcatccagca tgctggcaat
     6841 gatagcagca tccgcttcac cggtcagcag agccttgcga atgtcgggcg tcttcagctc
     6901 catcacccgt atatcaagat ccgggtattt ctccatcagt tgcggaaaga aacggggcag
     6961 aagataaggt gcaatcgtcg gtaacactgc caatcggaat gtacccgaca gggagtgctg
     7021 ttcttcgctg atgatctcct tgacacagat aacttccgaa agaatcttac gggcctgttc
     7081 cagcactttc ttaccaatgg cagtagggca aaccggtgtc atgctacggt cgaacagttt
     7141 cacccccaat tcgtcttcca gcttttggat cattgcactc aaagtaggtt gcgtcacccg
     7201 gcaatactcg gcagctttag caaaatgccg gaactggtcc acagccagaa tatattccaa
     7261 ttgttgtata gtcatcgttc tctgatttat taaagatata gaatctatca atgcaaagat
     7321 agaaattttc agtttgacac gaatcatttt gtgccgtatc tttgttccag ataaaaagaa
     7381 gaaatatagt attaactcaa aaaaaacaat atcattatga agactttaaa ttatacacat
     7441 ttggaagaaa aaggagctaa caccatcgta ctgtcattac agcaactgct tgccgatttt
     7501 cagattcatt atgcaaacct gagaggattt cactggaaca tcaaaggaca cggtttcttc
     7561 gtactgcaca gcaagtttga agatttatat aatggagccg ccgaaaaggt ggacgaaata
     7621 gccgaacgta tactgatgct gggaggaact cccgccaata aatacagtga ctatctgaag
     7681 atggcgcaga tcaaggaagt ggacggagtg aataaggccg acgacgctct gaatcatatt
     7741 ctcgaaactt acgggcatct gattgcggaa gaacgtaaaa tcctgtctct cgcctcttca
     7801 cacaacgacg aagtaacagt ggccatgatg agcgactacc tgaaagaaca ggaaaagatg
     7861 gtttggatgc tgactgcata caacggataa cagccgaaag ggtgtagcca tctgaccgaa
     7921 aaggtgtagc catacaaaca aaagggtgta gccatcccgg cgggatagct acaccctttc
     7981 tgttttattc gattcagatg atacttgtac gtttggtaaa ttcaataatc tccggaatgt
     8041 atccgaatgc gagcccggtc actgtatccg cacacccata atagatggca atccgtccgg
     8101 tctccgaatc atgaagcgcc gcgcatggga aacagacatt aggcacatca cccatacatt
     8161 cgtaatcctt ctgaggtgaa atcagataag gccccgaacg gaattttact ttccagggct
     8221 gattgatgtc aagcagtgcc gaaccaaaac tatacacaaa accgttgcag gaagccaata
     8281 caccatgata gatcagtaac cagccttccg aggtttcaat cgggataggc cctgcaccga
     8341 tcttggtaca ctgccaggca ctgtcttcga acggagccgg cgacataaca tgacgatgac
     8401 gtccccagaa ctccatatcg ggagactcgc tatagaaaat atctccaaaa ggagtatgcc
     8461 cattatcact cgggcggctc aacatcgcaa aacgaccgtt tatcttacga gggaacaaga
     8521 ctccattccg attgaaggga ataaaggcat tctccaactg gtgaaaagta acaaaatcat
     8581 aggtgtaggc cacaccgata gtaggaccat gatagccatt acaccaggtc acatagtagc
     8641 ggtcttcgat aaagcaaacc cgtgggtcat atccatagac ccaggttcca acctcagcgt
     8701 catcacattg aaactttaac ggttcttcgt tgatatccca atgaacagca tccttactga
     8761 atcccacatg caaacgcatg cgacgattag tatcatcaca acggaacacc cctgcatagc
     8821 catccttaaa cggaactacg gcactgttga atatactgtt tgaagtaggg agcaagtcgc
     8881 gcggaataat cggattggcc gaacaacgcc acactacatc tttacatcct gccggacgtt
     8941 cttcccaagg catagccggc aaagcagcac ctgcaatttt aatttcttcc atgattcgat
     9001 taaattaata ttatgtatat atcttgttta tattgaaaat ctctttttat ttcttctttc
     9061 cgtccggata tgtgaaaggt accagccaag tcacgataaa agccggtatg gtagcgataa
     9121 gtacccagat aaagaaatcg cgataaccca gccaatcgct caggtatccg ctcatcattc
     9181 cgggaagcat cacccccaga ttcataatac cggtagcaaa agcataatgt gccatctgat
     9241 gtttgccggg agccacttgc tgcatcataa agagcatcaa tccgacaaaa ccaaacccgt
     9301 aacccaagta ttcagacaca atggccatac caataatcca tagatcggaa ggctggtaaa
     9361 gggctaacag gaaatatacc aagaacggaa tattaaaagc gcaacataaa gaaaacaaag
     9421 tcttccgaag tccgaaagcc gaaatgtaat aaccggccaa aagcgaaccg agaataaaag
     9481 ctcccgctcc gaacgtacca tataccagtc cgatatcctg agtgctgagt cccaatccac
     9541 catccgcaac cgacgctttc aggaacaacg gtacaatctt gatggcatat ccttcggcaa
     9601 accggtacaa aatgataaag acaatgtaga aagcaatatg ttttttttgg aaaaaagagc
     9661 ggatgacttc ccaaagcata ttcaatgcgt cactcatcgt attcacttca ccggaagcgc
     9721 ctcctcccga aggcaaaatc cggatgtggt aaagaccgat cagaatcata atacccgcac
     9781 acatcaacat gacaatcatc caggcatgta ccactccaaa ttcatccttc agcatacctg
     9841 ccagccaaac caagcctccg ttggcaagta tcttggccag attataaaaa gctccctgcc
     9901 aaccgatata cttggcttgc tgggtagcag tcagttcagt caggtatact ccgtcacccg
     9961 caatgtcatg agtcgcacca ctgagagcaa tgatccccat cagagcgatg gcacaacgaa
    10021 aaaagtcggg cagcggcagc gaaagtgcta ccaatgcaaa tgccagtccg gtaataattt
    10081 ccgtagcgac aacaaagtat tttttcgttt taaacatttc cagaaacgga ctccataaag
    10141 gcttcaatgt ccagggaagc ataatgagag aagtccagaa agcaatctgt gcattcgaca
    10201 cttccatatc ggaaaacata aggacagaaa ccatcgaaag ggccacaaac ggcaatccca
    10261 tagcaaagta aacagtaggc acccaacata cagggcttat cggcttttta ttcatcagtt
    10321 agttttttat aataattcca tcggttaaca attccagtaa gcaaagatag gggatattaa
    10381 aaacataacc caagattacg acaagaagtt gctttcatta tttaataata caactcaccc
    10441 gggaaaacta ctaacctcta tcaccctttt tttattaaac tttatcaata caatacacgc
    10501 aaagaagcac cgaagacttt catccccgat gcctctcgcc cccttatcta caatctaaac
    10561 acctctattg cttcacatat aaatttatct cagcaaaccc ggtataatta tccggagtca
    10621 gacagtttat tctgaattcc tttacattcg ggataggtgg ttcgatggcc gcatattgcg
    10681 gatcagcccc tttaaaattt ctgaaagtca agactctcgg gtaagtaacc cactcggttt
    10741 caccctcttt ccgaacctta atctcagcac ttctcagatt ataacccgat ccgtaggcac
    10801 tctgtttagt gaccgaaaat ccggttaagg taacaggccg gtccagtacc gtattccacc
    10861 aacactctcc ggcattagcc actccccatg taaaccaagt agtatttatc tcaccgtcaa
    10921 tagccagatg tgcaccatat ttggcatcat catcggcata aacattgctg caacttacac
    10981 tccacgcact tcgatctaca gcggaccaat tcccgggttt cgtataactg gtataaagca
    11041 cgctggtata aatccggata taaaccgtct tcatagatgt actgacagcc tgttcgtcca
    11101 tgcccgtaac tcctttaagc gtcacgggaa gcacatatcc gccaggatta gtcaactttt
    11161 ctatattctt caaaacgacc tgaaaagatg aatcggccac tgtctgtccc gtttttaaga
    11221 caacttcact tgtttcaatg gtataattat cttggggcaa caacttacat ttcgtcttat
    11281 tggcagaatt gtaagtatcc actttcagcg tatctactcc caaagcggca gtggcatccc
    11341 gcgtaaccgg ctgtacggca cacaattgta tttcaaaatc agaacggtcg gcagtagagg
    11401 aattgctcac acaatccacc actaccgcag cacccatttc ggcccccggt gcaactcccg
    11461 ttctgatata tatcttttga tatttgtcca tttcatcatc atcgttgctg cacgaagcca
    11521 acgatacaaa gcctgttatc aggcagatta aggtcacaaa attcaaatgt ctattcatat
    11581 cttatcttct ttttacatag ttattgctta tcaaaacgaa catgctcttt ccagacaaga
    11641 gttcctcctg ccaccaaatc gtatccgtgt ccggtacagt cggcaaaggc atttccttta
    11701 ccttcatcca ttttccaata gcctatcagg ttcggatcgg cgggtttcac ggcaaaatac
    11761 atgttggact gaatttgcgt ctggctgatt gcgctcttcc aaagacgcac ctgggccatc
    11821 tgacaattgt tgcggaagta gctaccgctc gaaaccatgt tcatcttgtc gaatcttacc
    11881 gggccaccct ttgtctgcag agtcacgtcg agcactccgt tgatataaat cgacaataac
    11941 ccggaagaat tataaacgaa ggccagatga taccacttat tcttctcaaa caaagtcacc
    12001 gtattgacct gacttccaag tgtcttcacc tgtaatgaat tataagggat catagcgtca
    12061 ccgaaacgga tataaacctc gtggtcgctg ctgcccgaat taaatatagc ctgattatta
    12121 atatcgaatc cgtccatctg tacccaagcc tcgagtgacc attcattggt tgtcactccc
    12181 cacaattcgt ccttggcggg cttcacggca ttggtcgtat tcataaacgg tacagactgt
    12241 atcagcggct tatccagcaa aatgataaac ttcgacgaaa gcccgattgt agacaccggt
    12301 ccctgaattt ctgtgagaga taccggaata gcatacaatt ctccgttttc gtttgaataa
    12361 ggtttcactc taaactcact ggggattgcg ctaacatcgc ctgccgctat ctttatctct
    12421 ttgtcataag taaaatactg ctcgggaagg acttcgtacg aagtttcatt agcttcattg
    12481 tactctttaa gaatagaagg atctaccgtc aggacagcag tcacattttc ggttacaggc
    12541 tgtcccacac gtacggtcag agtagttgtt gttacatttt caggatcaac ggtaaccttt
    12601 gccgaaccat tctcggatgc ttcattcaaa taaatcgcat tgtcgataac ctggtaatcg
    12661 gcatcgttgc atcctgccag gatcatcggc agaacgaaac aggcaagcaa acattgtttt
    12721 attgttattc ttttcataat caaattcttt aaagtcattt tacagcagga ttcattattc
    12781 tgattgcttc acgcaggtac ttatattcga tgtcgcccgg atagtcatat tccatgtgat
    12841 aggtgcctac tccacccttc cgtacctgtt ttccgtcaat agtcggagtc cagcgtgcca
    12901 tgccggcaag tgctctcatt ttgtttccgt aacgatctac ataatcacct cctcctgtcg
    12961 gagcataaga ttcgaaattc tccgtaacga tgtacatatt agccactttc tccggaggaa
    13021 gtattccttt aaagttggca atcgtaccag ccagacgtct gtcaagatta gcgtcggaat
    13081 tacccgcaag gttagagtat gcctgcacaa tgaaatagtc aaagtaaggc ccggtttccg
    13141 gatgaatact ttgaggctcg ccatcaatca caagtaaccg tcccgtacct gatttaggtc
    13201 cgattcttt
//
