LOCUS       c00024_gnlPro..        15222 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEOIGKPM_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:44:08
            Original ID  :: gnl|Prokka|NEOIGKPM_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15222
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15222
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3870:7384]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3871..7384
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15222
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15222
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..235)
                     /locus_tag="ctg24_1"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKG"
     CDS             560..2116
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MNKLVLTGLLAAGTMTHLQGAQPAGQRPNILFILSDDHTSQAWGI
                     YGGVLAEYAHNANIRRLAKEGVVLDNCFCTNSISAPSRASILTGLYSHRNRLYTLADSL
                     DTSIPTLATLLQANGYHTGLVGKWHIQSQPQGFDYYSIFYDQGEYRDPTFIESTDPWPG
                     NRRFGERVLGFSTDLVTEKAIRWMKEQDGNQPFLMCCHFKATHEPYDYPIRMEHLYDGV
                     TFPEPENLLDWGPETNGRSFKGQTLEELERRWRIASQDPDKWWCRYPGLPFSTEGMQRT
                     AARRASYQKFIRDYLRCGATVDDNIGKLLNALDEMNIADNTIVIYVSDQGYFLGEHGFF
                     DKRMFYEESARMPFVIRYPKKVPAGKRLDDLILNVDFAPTLAEFAGVKMENVQGDSFVS
                     NLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYARNLDMTDTENFDFTPS
                     WDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLRKETGDTDGKYPEMQELLEKYYN
                     K"
     CDS             2800..3750
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MEERILFSQKTTIFVPVDNDSRIKPMSKDSLCAQHTDCSGCPKAM
                     ESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTTLHEKQFILQAIGSKY
                     EILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVMNPRLFYLINDVAAYL
                     DESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTESFQYFVMQNYSKAKNV
                     EEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQHSNMRITEICNRYGFD
                     SLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             3871..4575
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             4613..6592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7e-37, bitscore:
                     116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             6629..7384
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="Fer4_7 (E-value: 9.5e-13, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 6.8e-26, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(7492..7884)
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MDTLNLHSNFDNLLYIGRSVLNNTSSHIQKLFFKKEMCIYEYLYK
                     EEVSKGIEIKIDDVVLVCALEHDKCNKSILYFNDVANIARYIHYCNSNFEYKEELNGWI
                     MSDSYLALSISEDDYEKRFAFIQTLL"
     CDS             8010..8234
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MTEIMLDKQETLNEIGTKIRKLRESKNLSIQEFADKLEMEYNNVI
                     RIEKGRTNFTIGTLVKIANSLEVNLKDIV"
     CDS             complement(8412..9938)
                     /locus_tag="ctg24_9"
                     /transl_table=11
                     /translation="MRTKRAFKEFCVLGGLASSVCGVAQERPNIIVFLVDDMGLMDTSV
                     PFIADESGQPVRHPLNDWYHTPNMERLAKQGICFSTFYAQSVSSPSRASIMTGQNATRH
                     GVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPRVLQQAGYKTIHVGKAHFGCMGSEG
                     ENPLNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTI
                     EANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMD
                     KSLGDIMDQLEKLEIAENTLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRV
                     PFIAAWAKPEKKSKVQKNLPIEVGSMQTQLGTIMDIYPTVLSVAGCEVPQNYVIDGFDL
                     KKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLK
                     DDPEERNELSSAHPDKCREMIQEMSAQLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(10286..11128)
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MSSICQGTWDCQNCPKAVDNAIIHTTHTRGYHQPARKCEDNFILF
                     LIKGELLVNSQEYAGTMLKAGEFILQAIGSKYEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKDVPSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLSYYYSD
                     YDLASLVHPLSKYTTTFEYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFHEPVYE
                     WMQARRKEGILDDLNNSEYSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTSKKNV"
     CDS             complement(11469..12452)
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="MKKVLLAIAAVATITSCSQNEEFENPAQNAEINFSTIVSKSTRAV
                     IIENKDFKKFTAYGYSHGETNFTGVVTSTIMSSAEYTKGEDGGWTTSGRYYWPTSGKVT
                     FFGYGGVATATYAKEDGKFPTLKYTVLTDVNKQEDLLVAQQANKSKENNNPSVNLNFKH
                     ALAQVYFKLKGNDADLTYTVSKIELNKVRTEGTFTYGGDPDTSIGQWAVEDNASTGNYA
                     ITLNDQKVIGEAEATILNDALTQVMILMPQSLAGVEVKVTYSAEKGGLEVHSASEPVTV
                     KLTGNWEAGSKTAYVLSLNGDAINLTGSSDDTSWSEKTDVNTDVNK"
     CDS             complement(12505..13461)
                     /locus_tag="ctg24_12"
                     /transl_table=11
                     /translation="MQDTRYILLVLLSSLLMLTGCSRRELLDDYPVSGVDIKLDWNGVT
                     DKLPEGVRVIFYPKSAEGRKIDTYLSVRGGKVKVPPGRYSVVAYNYDTETVQIRGEEAY
                     ETIEAFTGYCNGLGIAGTEKMVWGPDPLYVVQINDLHIANSEEELLLDWKPKLVVKTYS
                     FKIKVEGLEYVSSIVGSVEGMAGCYCLGRCCGMMNDAPIYFEAQGCSGEVTGSFTAFGL
                     PEGAMSRASLAIKFTLAFVKVDNTVQKIEVDITDVIVNSESGEGGGNDEPSKDIELPLD
                     DDEVKVDKPENSSGGDGGIGGDVGDWGEEEEVPLPVI"
     CDS             complement(13469..14752)
                     /locus_tag="ctg24_13"
                     /transl_table=11
                     /translation="MKNGIYTCVILMAFLALSESVYAAIPVLTVASDTIRRVVIYFDKE
                     ETDIDFSYKTNNHEINVLDSLLEEKINSRYITALNVVTFVSPDGDSVYNAALSVRRNNS
                     MREFLRQRYPYVDVEKIKLTSEGEDWSELRKLVASDSDLPDREEVLMLIDYHRDNTVKR
                     KELLQKLNQGMAYRYIVRNVLPELRRAEITVVREVPEMEKNTFEPVSSVFGLFVSKQEE
                     ALPSDQPDKPEGESKESMAYEDEVVVSEAEGPVESKTVLAVKNNLLYDLALAPNLEVEI
                     PVGKRWSLNAEYKCPWWLNSKHDFCYQLLSGGVEGRCWLGNRQKRNRLTGHFIGLYAEG
                     GIYDFQWKGDGYRGDYYGAAGVTYGYARQLARHLSLEFSFGIGYLTTEYKKYTPYEGDI
                     VWTTSGRYNFIGPTKAKVSLVWLIKRGR"
ORIGIN
        1 ctcctttccc attctcaaag atacggggat tctcaaacga aagcgacccg tctttattgg
       61 gacggacgtt cagaaaaatc agatcatcac tcgcccttaa actctcggca gaaatacgtc
      121 cgcgattgta gaaattaccc cgtacatacg aactaatgaa gcagttttgt tgcgcataca
      181 acgataatcc gacaaacaag agaaggaaaa atacaatttt tcttggtagt agcataataa
      241 ttgataatta atgggttttg atcgcaaaag taggtacagg caaagaaaac aaatgttcaa
      301 aaatcactat aatacttcca aaaatcaaca taaagtttct tattgagaga tgtaaaacaa
      361 aaacatcctt ttaaaaaggg aattaagtgt tttaccggaa tcaattacat taaatcgcaa
      421 aagttttccg gattataata caaagtgaat aacaatcact atctttaggc ataaaatcag
      481 ttcatatgat catttatcta catgaaagca accgtctaac ttagactgac ttttgaagaa
      541 atgcaacatc tatacgtata tgaataaact cgtacttacc ggtctgctgg cagccggaac
      601 catgacgcac ctgcaaggcg ctcaacctgc cggacaacgc cccaacatcc tttttatcct
      661 gagtgacgac cacacctccc aagcctgggg catctatggc ggagtactgg cagaatatgc
      721 ccacaacgcc aacatccgcc ggctggcaaa agaaggggta gtgctcgaca actgtttctg
      781 caccaactct atctcagcac ccagccgtgc cagtatcctc accggtctat acagtcaccg
      841 gaacagactg tacacccttg cggactcact ggacacctcc atccccaccc ttgccaccct
      901 gctacaagcc aacggatacc acaccggact cgtcggcaaa tggcatatcc agtcgcaacc
      961 gcaaggattc gactactact ccatcttcta cgatcaaggc gaataccgtg acccgacttt
     1021 catagagagc accgacccgt ggcccggcaa ccgccggttc ggcgaacggg tgctcggctt
     1081 ctccaccgac ctcgtcaccg agaaagccat ccgatggatg aaagagcagg acggcaacca
     1141 gcccttcctg atgtgctgcc atttcaaagc aacgcacgaa ccctacgact acccgatacg
     1201 catggagcat ctctacgacg gcgtcacctt ccccgaaccc gaaaacctgc tggactgggg
     1261 accggaaacc aacggccgtt ctttcaaagg acagacactg gaagagctgg aacgtcgctg
     1321 gcgcatcgca tcacaggacc ccgacaagtg gtggtgtcgc taccccggac tgccgttcag
     1381 caccgaaggg atgcaacgga cggccgccag acgtgcttcc taccaaaagt ttatccgtga
     1441 ctacctccgt tgcggcgcta ccgtcgacga caacatcggc aaactcctaa acgctctgga
     1501 cgaaatgaat atcgccgaca ataccatcgt catctacgtc tccgaccaag gctatttcct
     1561 aggcgaacac ggcttcttcg acaaacggat gttttatgaa gaatcggctc gtatgccttt
     1621 cgttatccgt tatccgaaga aggtacccgc aggaaaacgt ctggacgatc tgatactgaa
     1681 tgtcgatttc gcaccgacgc tggcagaatt tgccggagta aagatggaga atgtgcaagg
     1741 agacagcttc gtcagcaacc tggaaggcaa cacgccgacc gactggcgaa aagaaatcta
     1801 ctatcgctac tggaccaatc atgctattcg tcccgcgcac ttcgccatcc ggtcagaccg
     1861 ttacaagctg atcttctatt atgcccgaaa tctagacatg actgatacgg agaactttga
     1921 ctttactccg tcatgggact tctatgactt acagaatgat ccgcacgaga atcataatgc
     1981 atacaacgat ccgaaatatg cacctgtcat caaacagatg aagaaagact tattgagact
     2041 tcgcaaagaa accggagata cggacgggaa atatccggaa atgcaggaac tgcttgaaaa
     2101 atactataat aagtaagtga ctggtacgga aactgaactg tcgcatttat aacttgaact
     2161 taggcagctg ctacaagtga aaaagatagc agttttgccc taacgctctc attattcgcg
     2221 tgtatccctt tattcatcgg catttcaagc attacagcaa gtatggtggc agagtgagag
     2281 caagggtttg ctctcactct gccaccacgg catataggtc gtttatccta cattatactt
     2341 tgatttactg ggtattaaca tctgacgcgt cagctattaa cgattgtcat gtcagctatt
     2401 aataattgag aaatcaggta ttaacagctg agaagtcatc cattattgac tgaaaaatga
     2461 aataatacct ttcgaacgga caggtcaatc agagcaactt atgcggtcaa gtgagttgaa
     2521 tcgagctgtc atatgaacga aatcgacagt tgttccaaga agtttcatta cttgaaacag
     2581 tttgtttcat gccttgaaac acttggtttc aacaggtgga actaatgatg aaactacttg
     2641 ttctgaatat atcatgtaaa gggatgaaga aaatgctgca gatggcagat aaaaatgtat
     2701 taatgtatta aagaacgcca ttcaggagtc cgtgaaactt caaagttgtg caaacaaaac
     2761 caataaagac aatcatatcc ccgtttctgc taaaacataa tggaagaaag aattttattt
     2821 tcacaaaaaa cgactatctt tgtccctgta gacaacgatt cacggataaa acccatgtca
     2881 aaagactcac tttgtgctca acatacagat tgctcaggat gccccaaagc gatggaaagt
     2941 actcttattc acagaaatct gctcagaggg cagcatattc cgaaggataa gtgcacgcaa
     3001 aactgcatgc tctttatgat cgagggcgaa ttgctgatca acagtgacga acatcccgga
     3061 acgacactac acgagaaaca gtttatcctg caagccatcg gctcaaaata cgagatactg
     3121 gcactgacgg acgtatcata catccttttc tggttcaacg aactgccgtt gctatgcgaa
     3181 aaccgctacc gtgaaatcat cgaccaggca gaaggcccgc tgacctacac cccaatggtg
     3241 atgaacccgc gcctgttcta tctcatcaac gacgtagccg cataccttga cgaatcgaca
     3301 cccgcctgcg gcaaatatat cgacctgaaa tgtcaggaga tggtgtatat gatcaccaat
     3361 tactatcccc tgccccagtt gagggctttc ttctacccga tcagcaccta tacggaaagt
     3421 ttccaatact ttgtcatgca gaattacagc aaagcgaaga acgtcgaaga attcgcacat
     3481 ctgggaggct ataacaccac caccttccgc cgtctcttcc gaaacttata cggcgtgccc
     3541 gtctacgaat ggatgctgga gaaaaaacgg gaaggcatcc tcgaagacct acagcactct
     3601 aatatgcgga ttacagagat ttgcaaccgg tatggtttcg actcgctgtc ccaccttgca
     3661 cacttctgca aagactcctt cggagacacc ccgcgcgcct tgcgcaagaa agcggccaat
     3721 ggcgaaaaaa tcggaaagat caccgattaa ggaattattt ctttaattct ttggtcaatc
     3781 aatctatttc ccctattttt gcagtctgta agaggtgtaa aacgtcgaaa ttttagttct
     3841 aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc tgtaggaagg
     3901 aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt tcacatggcg
     3961 atgaacttag ttgcaatcat ctcggctgat ggttacaaca tgatttgtga gtttttggga
     4021 gcaaactggt atgcgctggt agctaccgca gcactggctg ctcttttcat tattcacatc
     4081 atctacgcgt tctggctgac aatgcagaat cgcacagcgc gcggtagcga acgctatgca
     4141 gtagtcgaca aaccgaaaac tgtagagtgg gcttctcaaa acatgttggt gttaggcatt
     4201 atcgttatcg taggcctcgg tttgcacctc ttcaacttct gggcaaaaat gcagttgccg
     4261 gaactgatgc acaacctgga catgcacgct gatacactga cgctggctta tgcggcaaac
     4321 ggtgcatatc acatccagca gacattctct tgtccggttt atgtagtgct ctacctcatt
     4381 tggctgtttg ctctgtggtt ccacctgact cacggtttct ggagctccat gcaatcactg
     4441 ggatggaaca acaaggtatg gatcaatcgt tggaaatgta tttctaacat ctattctacg
     4501 attgtagtac tcggtttcgc actcgtagta gtggtattct tcgtgaaatc actcctttgt
     4561 ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata ttatgatcaa
     4621 gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact ataaagctca
     4681 ccagaaattg gtgaaccccg ctaataaacg ccgtttggat atcatcgttg tgggtacggg
     4741 tctggcaggt gcttctgctg ctgcatccct cggtgaaatg ggtttcagag tattcaactt
     4801 ctgtattcag gactctccgc gccgtgcaca ctctatcgct gcacagggtg gtatcaatgc
     4861 tgcaaagaat tatcagaatg atggtgactc cgtttaccgt ctgttttacg atacagtaaa
     4921 aggtggtgac tatcgtgcac gtgaagccaa cgtttaccgt ctggccgaag tgtccaacgc
     4981 tatcatcgac caatgcgtgg cacaaggtgt tcctttcgca cgcgaatacg gcggtacact
     5041 ggacaaccgt tctttcggtg gcgcacaggt atcacgtaca ttctacgcta aaggccagac
     5101 cggtcagcaa ctcttgctgg gtgcttactc cgcactgagc cgtcaggtaa acgtaggtac
     5161 ggtgaagttg ttcacccgtt atgaaatgca ggacgttgtg atcatcgacg gacgtgcacg
     5221 cggtatcatc gccaagaact taatcaccgg cgaactggaa cgtttcgctg ctcacgccgt
     5281 agtaatcgct accggtggtt acggtaacgc ttacttcctg tctaccaacg ctatgggttg
     5341 taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcta accccgcata
     5401 cgttcagatt cacccgactt gtatcccggt acacggtgac aagcagtcca aactgactct
     5461 gatgtccgaa tctctgcgta acgacggtcg tatctgggtt ccgaagaaga aagaagacgc
     5521 tatcaaattg cagaaaggcg aaatcaaggg aagcgatatt cctgaagaag accgcgacta
     5581 ttatctggaa cgccgttatc cggcattcgg taacctggtt ccacgtgacg ttgccagccg
     5641 tgcagctaaa gaacgttgcg acgcaggttt cggtgtgaac aacacaggtc tggccgtatt
     5701 cctcgatttc tctgaagcta tcaaccgcct gggcatcgat gtagtgcttc agcgttatgg
     5761 taacctcttc gatatgtatg aagaaatcac tgacgttaat ccgggcgaac tggcaaaaga
     5821 aatcagtggt gtgaaatatt ataatccgat gatgatttat ccggctatcc actacacaat
     5881 gggtggtatc tgggtagact acgaactgca gactaccatc aagggtctgt tcgctatcgg
     5941 tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttccgcat tgatgcaagg
     6001 tctggccgac ggttacttcg tattgcctta cactatccag aactatctgg cagatcagat
     6061 tactgttcct cgtttctcta ctgaccttcc ggaatttgcc gaagcagaaa aggcagttca
     6121 ggctaagatc gacaagttca tgagcatcca gggtaaagaa tcagttgatt ctatccacaa
     6181 gaaactgggt cacatcatgt gggaatacgt aggtatggga cgtacggcag aaggcctgaa
     6241 gaaaggtatc gccgaactga aagcagtccg caaggaattc gaaaccaatc tgtttatccc
     6301 cggttctaag gaaggtatga acgttgagct cgacaaggct atccgtctgt atgacttcat
     6361 cactatgggc gagctcgttg cttacgacgc attgaaccgt aacgaaagtt gtggtggtca
     6421 cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg aaaacttctt
     6481 ctacgtagct tgctgggaat atcagggtga cgatgaaaag gctcctgtat tgatcaaaga
     6541 accgctggta tacgaagcta tcaaggttca gacccgtaac tacaagagct aatcggtgaa
     6601 gttaaacatt taaaagaatt agacgaaaat ggataaaaat atatcattta cactgaaggt
     6661 atggcgtcaa gcaggcccga aggctaaagg cgcttttgaa acctaccaaa tgaaagatat
     6721 ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc tgatcagcga
     6781 aagaaaagaa ccggttgtat tcgaccacga ctgccgcgaa ggtatctgcg gtatgtgttc
     6841 tctttacatc aacggacatc cgcacggtcc tgcaacaggt gctactactt gccagattta
     6901 catgcgtcgt ttcaacgatg gtgacaccat cactgttgag ccttggcgtt cggccggttt
     6961 ccctgtcatc aaggacttga tggtagaccg tactgcttat gacaagatca tgcaggccgg
     7021 tggttatgta agcgttcgta caggcgctcc gcaggatgcc aacgctatcc tgatcccgaa
     7081 gcccatcgct gacgaagcta tggatgccgc ttcttgtatc ggttgcggtg cttgtgtagc
     7141 tgcttgtaag aatggttctg ctatgttgtt cgtttctgca aaggtcagcc agctgaactt
     7201 gcttccgcaa ggtaaaccgg aagctctgcg ccgtgcgaaa gctatgttgt ctaagatgga
     7261 tgaactcgga ttcggtaact gtaccaacac ccgcgcttgc gaggctgaat gtccgaagaa
     7321 catctctatc agcaacatcg cccgcctgaa ccgcgacttc atcatcgcta aactgaaaga
     7381 ctaagcgtga gcttgatttg attaatagca taaatccccc gtcggcgtta gctggcgggg
     7441 gattttcttt ttactcatta gcaaaagtat aataaaacga ctcagttaag ttcatagtaa
     7501 agtttgtata aacgcaaatc gcttctcata atcatcctca gatatagata aagcaagata
     7561 actatctgac atgatccacc cattgagttc ttctttatat tcaaaattac tgttacagta
     7621 atgaatgtaa cgtgcgatat ttgctacgtc attaaaataa agaatggact tattgcattt
     7681 atcatgttct aaagcacaga ctaagacaac atcatctatt ttaatttcaa tgcctttact
     7741 tacctcctcc ttatacaagt actcatatat acacatctct tttttaaaga ataatttttg
     7801 aatgtgactg ctcgtattat ttaatacgct tctacctata tatagtaggt tgtcaaagtt
     7861 tgaatgcaaa ttaagtgtat ccatctcatc atttttttta ttgttattac tcaactgaat
     7921 attccattag cattattata tctcaccata caatcatata tgattgcgga tatgcaaata
     7981 taaatacttt cctttgaaaa caatcatata tgacagagat tatgcttgat aaacaggaaa
     8041 ctttaaatga gataggtact aaaattagaa aattacggga aagtaagaat ctatctatcc
     8101 aagaattcgc agataaactt gaaatggagt acaacaacgt tattcgaata gagaaaggga
     8161 gaactaattt cactattggt actcttgtga aaatagccaa ttccctagaa gtaaatttaa
     8221 aggatatagt atagcaattt gagatgcaag gattatacaa ctccttagaa cgctaaccta
     8281 aggagctgta tatatgaagc ataactatta tcaactgaac ttcatatatt gactgaaatg
     8341 tctatgcaat tacatttaaa acaatttgcg gataagacat caatactctt gcaaaccaaa
     8401 atcaatgcca atcaaaagta aacaaaaggt ttcaactcat ttccttgttt atccaccgga
     8461 taaagagctc cttccttctc taattgagca gacatttcct gaatcatctc cctgcattta
     8521 tccggatgtg cggaagaaag ttcatttctt tcttccggat cgtctttcag attgtaaagc
     8581 aaggctttgg gttgtttcgg agtctcggga agataataat aaatcagttt ccagtcgccc
     8641 atgcgatagg tggtgaagta gctgccgcgg tgtgcgtgag ggaagtgcat caggaaagac
     8701 tcgggacgct tcttgtccac cttaccgctc agttgctttt tcagatcgaa tccgtctatc
     8761 acgtagtttt ggggaacttc gcatcctgcc acagacagaa cagtcggata gatatccatg
     8821 attgtgccca actgtgtctg catacttcct acttcaatag gcaagttctt ctgtactttg
     8881 ctcttcttct caggctttgc ccaagctgcg atgaaaggaa cacgcatacc accttcaaac
     8941 tccgtcccct ttttacctct cagcggagcg gaagaaccat agccacgttc atctcccaat
     9001 ggagcatcac caccgttatc tcctaaaaag agaatcagcg tattttcggc aatttccagc
     9061 ttttcgagtt ggtccatgat gtcgcctaat gatttatcca tgccttctat caatgtagca
     9121 aaagctcttg cctgctcgtt cttatccggg tcggtgtagc gtgacaagaa acgtttgtct
     9181 gcctggaaag gtgaatgaac tgcgtaatgg gccatattca gatagaaagg tcgtttttct
     9241 tctacggctt tggtgatctc ccgattcgct tctatagtca gcgcttcact caggaaggta
     9301 tctgtaccgt gatatttctc caggtcagga actgctctaa tcttctgtcc cttgatatgc
     9361 ccgtatcccc attcgccata atagctgccg ggatgtccaa tgccggaacc tgcgatattt
     9421 acatcaaagc cgatattcag cggattctct ccttcgcttc ccatacagcc gaaatgtgct
     9481 tttcctacat gaatggtttt atatccggct tgttgcagga ctctcggcat ggtaggcata
     9541 tcttttctga gacctttcca gttccattgg ggcggtccga aaggattccg attgttgctc
     9601 tcagcattaa tccagttagt gactccatgc ctggtcgcat tctgtccggt catgatggaa
     9661 gctctggaag gggaactcac gctctgtgcg taaaaagtag aaaaacaaat accctgttta
     9721 gccagtctct ccatattcgg ggtatgatac cagtcattca gcggatgacg caccggctga
     9781 ccactctcat ctgcgataaa aggaaccgac gtatccataa gtcccatgtc atctacaagg
     9841 aaaacaataa tattcgggcg ctcctgagct actccgcaaa cggaagatgc caaaccaccc
     9901 aatacacaaa attccttaaa agctcgtttt gttctcatta catagtattt atgatttata
     9961 tcctagttat tgtacgtgcc ataatagatt tcaaactcag actctcttct gattacacaa
    10021 aagagtatta gaaaaatatc ctattatctt tcattcattc agcataatct atcatgttat
    10081 tattctgctt tgaaacctga ttttaattcg ttgaaataaa aagtttaatt tccgtatccg
    10141 ccttatcatg gctttatttg aagtgatctg actttataat aaagatgtat tagactggtt
    10201 ttaaaggaaa cagctagcaa tatacaacaa atgtactaca cccacaaaga aaaaaatagt
    10261 ttttgacttt ctctctgaaa aattatcaga cgttcttctt gcttgttcta agcatacgtg
    10321 gagaagctcc aaagaacttc ttacagaaat tggagaagtg aggcagagac tcaaaaccgt
    10381 atttatagca tatttcggag atactgtact cagagttatt caagtcatcc aaaatacctt
    10441 ccttacgtcg cgcctgcatc cattcgtata ccggttcgtg gaatacatta ttgaagatac
    10501 gccgcaaggt gctgacggta taacctccca gttgagccag ttcttctacc gtttttactt
    10561 tcttatagtt ctgaaggatg aagtattcaa aagtggtggt gtatttcgag agtggatgca
    10621 ccaaactagc caagtcataa tccgaataat agtagcttag cacaaacgcc agttctttgc
    10681 gctttaaaga cagcagatcc cggcagactt tactttcact caaataggat ttggaaccat
    10741 ccaaaaagta tttcaattca ggaattatct ttaaaggaga atagataagc ggagaaggta
    10801 catccttcat gatatgattg aaacggaagt cacagaatag ttccggctga ataaaacgat
    10861 aatagataca ttcgcactcg gtcatcgcaa gcatctcgta ttttgaacca atagcctgaa
    10921 gaataaattc acctgctttc aacatcgtac ctgcatactc ctgactatta accaagagct
    10981 ctccctttat caaaaaaagg atgaaattat cttcacactt ccgggctggt tgatggtagc
    11041 cccttgtatg ggtagtgtga atgatagcat tgtctacggc tttcggacag ttctgacaat
    11101 cccaagtacc ctgacagatt gatgacatat atttgtgttg gcgtttgatt tgttcctgtt
    11161 tgcaacaaaa atatatgaaa tcttttacat ggcaatagaa aagggaggaa aagtgaaaaa
    11221 gaggttattt ttacattttt tttgtaatat aaaaaggaga gtatttttac ttttaaaaaa
    11281 gctattcact attttatatt atcaaaaatt cctaaatata aattttacac tagattttga
    11341 ctttcaaaca taactagaat taatttaaaa ttaggggact atctgaaata tcatcagata
    11401 aagtccccgg aatattttat tttcaaataa tcaaaacaga catttgtttc ttaataaata
    11461 cgtccaaatt atttatttac atcagtattt acatctgttt tttctgacca tgaagtgtca
    11521 tcagaagacc ctgtcaaatt tatagcatca ccatttaaag ataatacata agctgtttta
    11581 gaaccagctt cccagttccc tgtcaatttt accgtaacag gttcactcgc actatgaact
    11641 tcaaggccac ccttttctgc actatatgtt actttaactt ctactccggc taaggattgg
    11701 ggcataagaa tcattacctg tgttaaggca tcatttaaaa ttgtggcttc tgcttctcct
    11761 ataactttct gatcatttaa tgtgattgca taatttccag tagaagcgtt atcctctaca
    11821 gcccactgtc caatagatgt atcaggatca cccccatatg tgaaagtacc ttctgttctt
    11881 accttattta gttcaatctt agaaactgta tatgtaaggt ctgcgtcatt acctttcaat
    11941 ttaaagtaaa cttgagccaa tgcatgctta aaattcaaat taacagaagg attattgttt
    12001 tctttacttt tattagcttg ctgtgctact agtaagtctt cttgcttatt aacatccgtt
    12061 aacacagtat attttaaagt aggaaactta ccgtcttctt tagcatacgt tgcagtagcc
    12121 actcctccat atccaaagaa agtaacctta ccagatgtcg gccaataata acgccctgat
    12181 gtagtccagc ctccatcttc acctttagta tattcagcac tagacattat agtagatgta
    12241 acaactcccg taaaattcgt ttcaccatga gaatacccat aggctgtaaa tttcttaaag
    12301 tccttattct ctattataac ggctcttgta gatttactta caatagtact aaaatttatc
    12361 tccgcattct gtgctggatt ctcaaattct tcattctgtg agcagcttgt aattgttgca
    12421 actgctgcaa tcgccaataa tacctttttc ataatcgtat ttttttaagt ttataatatt
    12481 gttatatttt gcttatgctt tatctcaaat tacgggcaaa ggcacctcct cctcttcccc
    12541 ccaatcacca acatcaccgc caataccacc atcaccacca gacgaatttt ccggcttatc
    12601 aaccttcacc tcatcatcat caagcggtaa ctctatatct ttagaaggct catcgttgcc
    12661 tcccccttca ccactctccg aattaacaat cacatccgtt atatcaacct ctatcttctg
    12721 taccgtatta tccaccttca caaatgccag cgtaaacttt atagcaagac ttgcccgact
    12781 catcgcccct tccggtaacc caaaagcagt aaaactaccc gttacttcgc ccgaacaccc
    12841 ttgcgcttca aagtagatag gagcatcgtt catcatcccg caacatctgc ccaaacagta
    12901 acaacccgcc ataccttcca cactgcctac aattgaagaa acatattcca gcccttccac
    12961 cttgatcttg aaagaatagg tctttaccac taatttcggt ttccaatcca gtagaagctc
    13021 ttcttcactg ttcgctatat gtaaatcatt gatctgcact acgtataagg gatcaggtcc
    13081 ccataccatt ttttccgttc ccgctattcc cagaccattg caatagcctg taaatgcttc
    13141 aatcgtctca taggcttcct ctcctctgat ctgcaccgtt tcagtgtcgt agttgtaagc
    13201 cactaccgag taacgccccg gcggcacctt tacttttcca cctcttactg aaaggtatgt
    13261 atcaatcttt ctgccttccg cactcttcgg ataaaaaatc acccgaaccc cttccggcaa
    13321 cttatcggta acaccgttcc aatctaactt tatatctacc ccgcttacgg gataatcatc
    13381 caatagttcg cgacggctac atccggtcag catcagcagc gaggacagaa gcacaagaag
    13441 tatgtatctt gtatcttgca taacgtcctt atctccctct ttttatcagc cataccagag
    13501 agactttcgc cttggtagga cctataaagt tataacgtcc actagttgtc cacacgatat
    13561 ccccctcgta aggagtatat ttcttatatt ctgttgtcag atacccgatg ccgaagctaa
    13621 attcgagcga cagatggcga gccagttgcc gcgcataccc gtaggtcact cccgcagctc
    13681 cgtaataatc gccccgataa ccgtctccct tccactggaa atcgtaaatt ccaccttcag
    13741 cataaagccc aataaaatgc cctgtcaacc ggttgcgctt ctgacgattg cccaaccagc
    13801 aacgtccttc cactcctccc gaaagaagct gataacagaa atcatgttta ctgttcagcc
    13861 accacgggca tttgtattca gcatttaaag accacctttt gcctaccgga atctctactt
    13921 ccagatttgg cgccaacgcc aaatcgtaca acagattatt cttcactgca agcaccgttt
    13981 tactttcaac cggcccttct gcctccgaca ctaccacctc atcctcataa gccatactct
    14041 ctttactttc tccctccggc ttatcaggtt gatcgctcgg aagcgcctct tcctgctttg
    14101 aaacaaacaa tccgaagaca gaagataccg gttcaaaagt attcttttcc atttccggaa
    14161 cctcccggac aaccgtaatc tcagcgcgtc tcaactcagg taacacattg cggacaatgt
    14221 atcggtaagc cattccctga ttcaacttct gcaacagttc ttttcgcttc acagtgttat
    14281 cccgatgata atctatcaac atcaagactt cttcccggtc cggcaagtct gaatccgacg
    14341 ccaccaactt acgaagttca gaccaatctt ctccttccga agtaagttta atcttttcga
    14401 catcaacata cggataacgt tgccttaaga actctctcat cgaattgttt cttcggacag
    14461 ataatgcggc attgtaaacc gaatctccgt caggcgatac aaaagtgacc acattgagcg
    14521 cagtgatata tcttgaattt attttttctt caagcaaaga atctaaaaca ttaatttcat
    14581 gattattagt tttataacta aaatcaatat ctgtttcttc cttatcgaaa tatatcacca
    14641 cccgcctgat agtgtcactc gcaaccgtga gaaccggaat cgctgcatac acactttctg
    14701 ataaagcaag aaatgccatg agaataacgc atgtatagat cccgtttttc ataattgttc
    14761 gtttctgtga acaaatatag aagttaataa ctaaataaaa tcatactacc ggaacaaaaa
    14821 aacaggcttg gaaggttctg tgaaacgatt ggaaggaatt tgcaagtttt aagagtatgg
    14881 atggatagaa caagcgtaaa aaagcgaaac tccagaagtt gaaaagctat ttttccacga
    14941 tactacacag aagttataaa tgaaaaacat ctgccatctg caacaaaatc gaaataacta
    15001 tttaatcaac atttgattac agcgttgcag atacctgttg cagataagtg acagatacca
    15061 ccatctgcaa caccggtata aacagggaag gcgcccctta taacgcaaat ggaagataac
    15121 ctcctattat cggagaaatg atttccgaag cagaaacgac agtatccagg aaggaaacga
    15181 tagttcccaa ggcgggaaac gatagttccc aaggcaagat ac
//
