LOCUS       c00036_gnlPro..        13866 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEOIGKPM_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:44:08
            Original ID  :: gnl|Prokka|NEOIGKPM_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13866
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13866
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1727:11919]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1728..11919
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..13866
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13866
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..1678
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="DFSSQLLFLKEVLDNNSYREKDIFFPQTELYTHWIVYSPEKDEVV
                     GLFTDSTEAVKTNRALDRSEKLFKSIFANIPAGVEIYDKDGFLIDLNNKDLEIFGVENK
                     QDVIGVNFFENPNVPQYIRDRVRDEDLVDFRLNYSFERAEGYYHPDRRDTIDIYTKVSK
                     LYDNEGNFNGYILISIDNTEQIDAMNRIRDFENFFLLISDYAKVGYAKLNLLNRKGYAI
                     KQWYKNLGEEEDTPLADVVGVYRNMHPEDRERIFDFYREVRKGNRKHFQGEMRICRPGK
                     KNEWNWIRMNVVVTTYNPEENEVEIIGINYDITELKETEKELILARDKAEMMDRLKSAF
                     LANMSHEIRTPLNAIVGFSDLLVDTENIEERREYIQIVKENNDLLLQLISDILDLSKIE
                     AGTFEFTNGDVDVNMLCEDIVRSMQMKVKENVELMFDPHLAECRIISDRNRLHQVISNF
                     VNNAIKFTSEGSIRVGYKQKGEELEFYVQDTGVGIDAESQAHIFERFVKLNSFVHGTGL
                     GLSICQSIVEQMGGKIGVESEPGKGSRFWFSLPCFVVMSEE"
     CDS             complement(1728..3170)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="Proton_antipo_M (E-value: 3e-72, bitscore:
                     233.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLHMREELSLVAVLLLLFLADLFMSPDAHKQKGTRPVLNT
                     MLPVILMAIHTAINLVPSTAADIFGGMYHYVPMHTVVKSILNIGTLIVFLMAHEWMKRD
                     DTSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEA
                     GAKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMALVFFFTGMAFKL
                     SLVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLMAILIKVFAPMIHDWQEVLYWVT
                     IASITIANIFAIRQQNLKRLMAFSSISQAGYIMLGVIGGTAQGMTAMVYYILVYAAANL
                     GVFAVITIVALRSQKFTLEDYAGLYKTNPKMAFLMTISLFSLAGIPPFAGFFSKFFIFM
                     AAFEAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTL
                     GIIGLGIASIVYQSIDKLSFGI"
     CDS             complement(3208..4692)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.6e-68,
                     bitscore: 220.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFMYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISIDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELTGLMKVMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLALTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             complement(4775..6664)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="Proton_antipo_N (E-value: 1.5e-25,
                     bitscore: 79.0, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 3.6e-87,
                     bitscore: 282.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFLSFLILGIGGKWMSHRTAGAIGTLILGAVVVLS
                     YVTAFQYFSAPRLEDGTFATLIPYNFTWLPFTETLRFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGETGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIAYA
                     PDTLHMIAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMDPHHGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPAMGWVMTVIAAMTAFYMFRLYYGIFWGKGNKELH
                     AHHTPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIHLDLSVAVTSVVIAI
                     ISIGIATWMYKNAKQPVANALAKRFNGLWTAAYHRFYIDDIYQFITHKIIFRCISTPIA
                     WFDRHVVDGFFNFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGALALILLLVL"
     CDS             complement(6752..7060)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="Oxidored_q2 (E-value: 2.7e-22, bitscore:
                     68.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDDLKW"
     CDS             complement(7156..7668)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Oxidored_q3 (E-value: 5.7e-37, bitscore:
                     116.4, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKLKRSRFLAGLFTMVAG
                     LAIILFITLKHNFLQTTNLVPLEINIHTIGNALLSSDKYGYILPFEAISILLLACIIGG
                     IMIARKR"
     CDS             complement(7671..8192)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-13, bitscore: 40.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.3e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPLASTSKIRIMEYKDQKYTYLGGLIHGISTLATGMKTSIKVYFR
                     KKVTEQYPENRKELKMFDRFRGTLAMPHNENNEHRCVACGLCQIACPNDTITVTSETIE
                     TEDGKKKKILAKYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLQLNHAG
                     SKVIEKKKEV"
     CDS             complement(8170..9246)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_8"
                     /sec_met_domain="NADHdh (E-value: 3.9e-123, bitscore:
                     400.3, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSVMPEGWAIFIECIAVGVCIVALYAILAI
                     VLIYMERKVCGFFQCRLGPNRVGKWGSIQVICDVLKMLTKEIFTPKDADRFLYNLAPFM
                     VIIASFLTFACIPFNKGAEILNFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLMGTMQFSEIVEGQADGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMHFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNAVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             complement(9372..10988)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_9"
                     /sec_met_domain="Complex1_30kDa (E-value: 4.9e-37,
                     bitscore: 117.1, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 1.7e-65,
                     bitscore: 210.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNEERRIMQEIQFIVPAALHDEMLRLRNEKQMDFLESLTGMDWG
                     VADEKDAPEKLRGLGVVYHLESTVTGERIALKTAVTDRERPEIPSVSDIWKIADFYERE
                     VFDYYGIVFVGHPDMRRLYLRNDWVGYPMRKDNDPEKDNPLCMTNEETFDTTQEIELNP
                     DGTIKNREMKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEK
                     MNESLTYPQTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSDRVKYIRTIMDELQRID
                     SHLLFYSALAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNF
                     VKRVKEFIPYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWA
                     CDVRKRIPYGVYDKVDFQEIVYTEGDCFARYLVRMDEIMESLKIIEQLIDNIPEGPYQE
                     KMKPIIRVPEGSYYAAVEGSRGEFGVFLESQGDKMPYRLHYRATGLPLVAAIDTICRGA
                     KIADLIAIGGTLDYVVPDIDR"
     CDS             complement(10985..11578)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_10"
                     /sec_met_domain="Oxidored_q6 (E-value: 5.4e-26, bitscore:
                     80.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVFLGVLDDL
                     VNWGRSNSLWPLTFATSCCGIEFMALGAARYDMGRFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVLNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGTNRKEKKPEFMK"
     CDS             complement(11569..11919)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_11"
                     /sec_met_domain="Oxidored_q4 (E-value: 4.5e-38, bitscore:
                     119.3, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMHDMGPQGLVSILFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             complement(12033..12410)
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MKQSLKYGLFLVLALLIHVVSNEAMEDNCRVSPPTYRQEKCYVSQ
                     DHPVHNALERLHYFYSTQSCDMSHADVAHIPTDKSVQLLITYFREYKSQQNTSQTHSLH
                     IPKYFYDPITYYIYGLRKIVI"
     CDS             12670..13866
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MKHTLCFITILLGSLLDLYANNENDSLLKVLDKVISERLVYTEKK
                     EATIKELKAKKKEQKTLDDMYRLNSEILHQYETFVCDSAEQYINENIEIAKKLDNKTYL
                     LEGRLQLAFVYSLSGLFIQANDIFKSINCSDLPSHLQALYCWNRIRYYENLIKYTDDAR
                     FASEYLIEKEAYRDTVMSILYDASEEYSKERAIKLQDQGNTKEALKILTKIYQKEKPGT
                     HGFAMMSMGLSRAYRLVGEHELEEKYLILAAMTDIKLAVKENEALLTLAVNLYHKGDID
                     RSYNYIKVALSDAIFYNSRFKNTVIARIHPIIENTYLYRLEKQKQNLRFYILLTSLFVV
                     ALAITLYFTYKQTKIVSRAKKNLNVMNEELVALNKNLDEANLIKERYVGYFMNQCAVYI
                     "
ORIGIN
        1 ggatttttct tcacaactcc tctttctgaa agaagtgctg gataacaatt catacaggga
       61 aaaggatatc tttttcccgc agacagagct ttatacccat tggatagttt attctccgga
      121 aaaagatgaa gtggtaggtc tgtttacaga ttccacggag gccgtgaaga ccaatagggc
      181 actggaccgt agtgagaagc tctttaagag tatctttgcc aatatcccgg caggagtgga
      241 aatctatgat aaggatggat tcctgattga cctgaataat aaggacctgg aaatattcgg
      301 tgtagaaaat aaacaggacg tgataggagt caacttcttt gagaatccga acgtaccgca
      361 gtatatccgt gaccgtgtgc gggatgaaga tttggtagac ttccgtctga attactcttt
      421 tgaacgggca gaaggttatt atcaccccga tcgtcgggat acgatagata tatatacgaa
      481 agtcagcaag ctctatgata acgaaggaaa ctttaacggc tatatcctga ttagcattga
      541 taatacggag cagattgatg cgatgaaccg tattcgtgat tttgagaatt tcttcctgct
      601 catatcggat tatgcaaagg tgggatatgc caagttgaat ctgctgaacc ggaagggata
      661 tgccattaaa caatggtata aaaatttagg tgaagaagag gatactccat tggcggacgt
      721 ggtgggagtc tatcgtaata tgcatcccga agaccgtgaa cgtatttttg atttctatcg
      781 ggaggtcaga aaaggaaacc ggaagcactt tcagggagaa atgcgaatct gccgtcccgg
      841 caagaagaat gaatggaact ggatacgtat gaatgtagtc gttacgacat acaatccgga
      901 agaaaacgaa gtggaaatca tcggtatcaa ctatgatatt accgaactga aggagacgga
      961 gaaagaattg atcctggcac gtgacaaagc tgaaatgatg gaccgtctca aaagtgcttt
     1021 ccttgctaac atgagccacg aaatacgtac tcctctgaat gccatcgtcg gcttttccga
     1081 cttgctcgtc gatacggaaa atatagagga acggcgggag tatattcaga ttgtgaagga
     1141 gaacaatgac ctgcttttac aactgatttc ggatatactc gacctgtcta agattgaagc
     1201 gggtacattt gagtttacca acggagatgt agacgtgaat atgctctgtg aagatattgt
     1261 ccgctccatg caaatgaagg tgaaggagaa tgttgaactg atgttcgatc cgcatcttgc
     1321 ggaatgccgc attattagtg accgtaaccg actgcaccag gtaatctcca attttgtgaa
     1381 caatgcgatt aagtttacct cggagggaag tatccgtgtg ggatataagc agaaaggaga
     1441 agaactggag ttctatgtac aagatacggg agttggtatt gacgcagaga gtcaggcaca
     1501 tatttttgaa cgttttgtga agctaaactc ctttgtacac ggcacgggtc tgggactctc
     1561 catctgccaa agtattgtgg aacaaatggg cggaaagata ggggtggaat ccgaaccggg
     1621 aaagggttcg cgtttttggt ttagccttcc ctgttttgtg gtgatgtcgg aagaatagac
     1681 aagaatgatg gggctgacta aaaagtcagc cccaaagagt cggtttctta tattccgaat
     1741 gatagtttat cgatagactg atatacgata cttgcaatac ccagtccgat gatgcccagt
     1801 gtgcagagcg ccagtcccca ctttgtacag cggtcgctgc ggaaagtcgg aatcgggtta
     1861 tcggaaggcg tgatatacat tgcttttaca atcagcagat agtagtacaa tgaaatcacg
     1921 gtattaacca gtgcaatgaa taccagcaag tggaagcccg cttcgaaagc tgccatgaaa
     1981 ataaagaact tcgagaagaa tccggcaaac ggaggaatac ctgccagtga gaacagcgaa
     2041 atagtcatca gaaaagccat tttcgggttc gtcttgtaga gtcctgcata atcttcgagg
     2101 gtaaacttct gactgcgtaa tgctacgata gtgatgacgg caaatactcc gagattggca
     2161 gcggcatata caagtatgta atataccatg gcggtcattc cctgtgccgt tcctccgatt
     2221 acacccagca tgatatatcc tgcctgcgaa atactggaga acgccatcag acgtttcaga
     2281 ttctgctggc ggatagcgaa tatattggcg atggtgatag aagcgatagt cacccagtaa
     2341 agtacttctt gccagtcatg tatcatcggt gcgaatactt tgatcagaat tgccatcagc
     2401 acaaatgctg ccgaaccttt ggagataaca ctcagatagg cggtaaccgt actcggtgca
     2461 ccttcgtaaa catctgccgt ccataaatgg aacggaacca gagagagctt gaacgccata
     2521 ccggtaaaga agaatacaag agccatgatt tgcaacggat ttccatcgat atgagcagga
     2581 agatcatcga aatacagtgt tcctgcggaa ccgtaaatca ttgacagacc aaacagtaac
     2641 agtgcgctgg agaaaagtgc ggtaaggata tacttggcac cggcttcagc ggagttatgg
     2701 cggtatttgt cgaaagcgat caaggctgcc atcgggatgg aagctgtctc cagtccgatg
     2761 aagaacatca ggaagtgtcc ggcggaaatc atgagataca taccgaacag ggtggagagt
     2821 gtaagtacat agaactcacc ttgcttgaat gaagtatcgt cgcgtttcat ccattcgtgt
     2881 gccatcagga aaacaatcag cgtgcctatg ttcaggattg atttgacaac cgtgtgcatg
     2941 ggtacatagt gatacatacc gccaaaaatg tcggcagctg tgcttggaac cagattgatc
     3001 gctgtatgga tggccatcag gataactggc agcatggtgt tcaaaacggg tctcgtccct
     3061 ttttgcttgt gtgcgtccgg actcatgaag agatcggcaa ggaacagcaa tagtaaaact
     3121 gctacgagcg acagctcttc ccgcatatgt agaaattgtg aataatccat ctttataaat
     3181 taagaattaa agattaaaaa ataaaggtta tgggatgagt tgtgagacta cagggagtac
     3241 actttcacca atcatgtggc ttacccagaa aggagccata cccagtccgg ctacacaaac
     3301 gatgaggcag ataacagcta cccgttcatc ccaggttgcg tctgtcagcg caagatgatg
     3361 tttgttggtg caggtaccgt acagaatctt gcctaccaga cgcaggatat agactgccgt
     3421 gatcacgatg gatgaacaag cgatgatggt cagtgtacgg tggaatacgt cgttgttctg
     3481 gaaagaacct acgaagatag tcatttcggc aatgaacccg cttaatcccg gcaaaccgag
     3541 attggcaaga ccggcaatca cataacatac gctgaggaac ggcattactt tcattaatcc
     3601 ggtaagctcg cggacatcac gtgtgtgtgt acgtccataa atcataccga tcagggcaaa
     3661 gaacaaggct gtcatcaatc cgtgggaaag catctgaaga atggctcctg tcgcagcagt
     3721 ctgattcagc atcagaatgg cgaaaagtac cagtccgcag tgagagacgg aagagtaagc
     3781 gttgatgtat ttcaagtctg tctgtacgca agcggagaat gctccgtaaa caacggagat
     3841 acctgtcagt atcaggaata tccatgaaag ctcgttagcg gcttccggca tcagatacat
     3901 ggcgatacgg aaacatccgt aacctcccag tttcatcagt actccggcgt gaagcatgga
     3961 tacggctgtc ggggcggaag cgtgaccatc gggactccat gtgtggaacg ggaaaagagc
     4021 acccaacaca ccgaacccga ggaaggtaag cgggaaccag atacattgct gtgcaaaagg
     4081 aatattatgt agctgtgcta tttccagcag gttcatggtg gtagctcccg aaccgaaata
     4141 gattccgaga ataccgatca gcaggaaagc ggaaccgccc atcagcataa gggtcagctt
     4201 catggctgca tattctttac gtcccgaacc ccatacaccg atcagcaggt acataggaat
     4261 cagcgcgatt tcgtagaaca tgaacatggt gaataagtcg atggatataa agaatccgaa
     4321 gactcccata gacaacagtg tgaaccaaag gaaatattct tttgtcagag gctgcagacg
     4381 ccaggaggcg aaagtacctg tgaatacaat aacggcagac aataacaaca tggctaccga
     4441 aataccgtca acgcctaccg aataggagat gtgaagcggt gcataccaga gtgtatccgc
     4501 acggaatagc atttctgccg tgttgccggc actgcgttct cccaaataca taaaggtaag
     4561 tacgacggag gcaatcagaa gtgccgatgc gccggtaacc ataacccccc gaatcgcttt
     4621 gattccccgt gctgcccaaa gtccggcaag catcagtaag gggatgagta cgaagattga
     4681 taaaaaattc ataattgaat tattaagttt taagtattaa ttcgcagcga cttgttgcgc
     4741 agcttaatat ctaatacctg atagttaata cttgctatag aactaacagc aggataagcg
     4801 ccagcgctcc gcaaaggaac acgtatgcgt attgctgtac ctgaccgctt tgaagaccac
     4861 gtatctcgtc gcttgtcgta ttcgtagccc atgccaggaa attaaagaat ccatccacta
     4921 catgacggtc gaaccatgcg ataggagtcg aaatgcaacg gaagatgatc ttatgcgtaa
     4981 taaactggta tatatcatca atataaaaac gatgataagc agctgtccac aatccattga
     5041 accgtttggc aagtgcattg gcaacaggct gtttggcatt cttatacatc catgtggcaa
     5101 tcccgataga aataatcgca attacaacgc ttgtgacagc taccgacaga tcgaggtgaa
     5161 tagagtaaga ctctccattc gaactgataa aatgtccgaa aggaatgaac cctgcaccac
     5221 aagtaacaac cgccagaaac atcaacggaa aagtcatagc caacggactc tcatgcgggg
     5281 tgtgatgagc atgaagctct ttatttcctt tgccccagaa gatgccgtag tagaggcgga
     5341 acatatagaa ggcggtcatt gcggcgatta ctgtcatcac ccaacccatt gcagggctat
     5401 attggaagca ggcagccaaa atctcatctt ttgagaagaa accggagaac ggaggaatac
     5461 cggcaatggc gagacaggca atcaggaatg tccagtgagt aataggcatg tatttgcgta
     5521 gtcctcccat ggctgacatt tcgttggaat gtactgcatg gataatgctg ccggcaccca
     5581 agaagagtaa tgccttaaac atggcgtgtg tgaagaggtg gaacatggaa gccatatatc
     5641 ccagtcctcc gtggtgcggg tccatagaag tacaaacgcc cagtgctacc atcataaaac
     5701 caatctgtga aatggtcgag aaggccagca cacgtttgat atccgattgt acgcaagcca
     5761 cgcttgctgc ataaaaggcg gtgaaagcac ctacccaggc aatcatatgt aaggtgtccg
     5821 gtgcataagc aatgaaaagc gggaacatac gcgctaccag ataaacgccg gcaactacca
     5881 tcgtagccgc atggatcaag gcactgacag gagtaggacc ttccatggca tcgggcagcc
     5941 agatatgcaa cgggaacatg gcactctttc cggcgccacc gataaacatc agtcccaaag
     6001 ccaatggaag catggaagcg ccgccactga tcaatgatac cgtatccggt gtgaagccga
     6061 atgtgccacc gtagtatccg taaatcagaa taccgataag gaagcctaag tctgcaaagc
     6121 gggtgacaat gaacgctttc ttggaagcgg caatggcagc aggctttgta tagtaaaaac
     6181 cgatcagcag ataagaactg acacccacca gttcccagaa aagatacatc tggaaaatgt
     6241 ttgtggcaac aaccagtccc agcatagaca tcgtaaacag ggacaggaaa gcgtaataac
     6301 gttgaaagcc cgtctcacct ttcatgtagc cgaaggagta gatatgcacc atcagtgaca
     6361 cggtagaaat gacaatcagc atcatcacgg atataggatc tagcagaatg cccagatcaa
     6421 atcgtaaagt ctcggtgaaa ggaagccacg taaaattata aggtatcaat gtggcaaatg
     6481 ttccgtcttc caaacgaggg gcggagaaat attggaaagc cgtaacgtac gatagtacta
     6541 ctactgctcc cagtatcagc gtaccgatag cacccgctgt ccgatgagac atccattttc
     6601 ctccgattcc cagaatgagg aaggagagga agggaagaag gagtattaga attgttagtt
     6661 ccatacagtt tattttaatt acttgtttta ttattgttca tatttatcac gatatccatc
     6721 cgaatggaaa ttgggtcgtg ccgctttggc actaccactt cagatcgtcc agattgcgga
     6781 cttgaatgct tcggaggttg cggtaaatgt taatcatgat ggcgatagct atagccgttt
     6841 ccgcagccga aatagcgatg gaaaagagtg caaagaaata gccttccatg cctcccggaa
     6901 agagaaaacg gttgaacacg gcgaagttga tgtccgtggc gttcagcatt aactctacag
     6961 aaatcaggat agccagcgta ttacggcggg taaagaaccc atagattcct gcaaacatca
     7021 tgatggtaga aactaccaga taatattcca tgtgtatcat atctgaaatt attaggtttt
     7081 aagtaataag tattaattcc ttgcggttca ttgcgcagcc taatacctga tacttaatag
     7141 ttaatactta cttatttatc tctttcgggc gatcatgata ccaccgatga tacaagccag
     7201 caataaaata ctgattgctt cgaaaggcaa tatataacca tatttgtcac tgcttaataa
     7261 agcattacca atggtgtgga tgtttatttc cagcggaacc aggttggtcg tttgcaggaa
     7321 gttatgcttc agggtgataa acaagataat cgctaaaccg gcaaccatcg taaagagtcc
     7381 tgccagaaac ctgcttcgtt tcagtttctc ggcgcggtca ccttctccac tggtcagcag
     7441 gatggagaat acataaagga cgacgatacc accggcataa accataatct ggacagaccc
     7501 cagaaatgtg taacccagca ggaaatagat gccagccgtg ccgaagagca cgaagagcag
     7561 ataggtggct gagcggacaa tacgttgggt agtcaccgtc atgatggaca ttgcaataat
     7621 aaatgctgcc aaaaagtaga atactactgt ttcaagtgtt gatcccatat ctaaacttct
     7681 tttttctttt caattacttt actaccggca tgattcagtt gcagaacaag cttcgtccgg
     7741 tcaaagacgg catgttcgaa gttctggtcg aacgtgatgg cgtcatgcgg acaagcgttg
     7801 acacacagtt ggcagaacat acaagctccg aggtcatatt catattttgc caggattttc
     7861 ttcttcttgc cgtcttcagt ctcgatcgtt tcgctggtta cggtgattgt atcgttcgga
     7921 caagctatct gacacaatcc gcaggctaca cagcggtgtt cgttattctc attgtggggc
     7981 attgccagtg taccacggaa ccggtcgaac attttcagct ctttccggtt ttcaggatac
     8041 tgttcggtta ccttcttacg gaagtatacc ttgatactgg ttttcatacc cgttgccaga
     8101 gtgctgatac catgtatcag tcctcccaag tacgtatatt tttgatcttt atattccata
     8161 attcttattt tagaagtgga agccaaaggc aacacaacat gccattaata ataggtttac
     8221 catagaaatt ggaaccagat atttccattc cagattcaga atctggtcga tacgcaggcg
     8281 tgggaaagtc catttgatcc acattaagag gaacacaacg aagaatgctt tggcaaagaa
     8341 ccagatgaag ccgggaatat agtccataac agcgttgaat ccgtccaaac cgacgatatg
     8401 caatggcatc cagcctccca aaaagatggt agcggccacg ctggctacga taaacagatt
     8461 cagatattcc gccagataaa agaaaccgaa gtgcataccg gaatattccg tatgatatcc
     8521 ggccgtcaat tcactttccg cttcgggaag gtcgaacggg ccacggttac attctgcatt
     8581 tccggcaatg agatagatga tgaaagcgat aacggcagga atatgtcctt tgaagataaa
     8641 ccatccgtca gcctgtcctt ctacgatttc ggagaactgc atggtgccca tcagtacgac
     8701 catcgtcatg atgctcatac ccactgacaa ctcataactg atgatctgtg cgccgcttcg
     8761 catggcaccg atcagcgaaa acttgttgtt actaccccaa ccggcaagca gaatacctac
     8821 cacaccgatg ctggaagcag ccagcaggaa gaatacgccc acattaaaat tcagaatttc
     8881 cgctccttta ttaaaaggaa tacaagcgaa agtgaggaac gaggcgataa tcaccatgaa
     8941 tggagccaga ttgtagagga agcggtcggc atccttcgga gtgaaaatct ccttggtcag
     9001 catcttgagt acgtcgcata tcacttgaat agaaccccat ttaccgacac ggttcggacc
     9061 gaggcggcac tggaagaaac cacagacttt gcgttccatg taaatcagta cgatagccag
     9121 aattgcatat agtgcaacga tgcacacgcc gacagctatg cactctataa agatggccca
     9181 tccctccggc ataacggaga gcagcagctc atgtatccag tttgttacta tactaaagtc
     9241 gaacatatat attttaatta ttaggtttta agtattaagt attaattcca tgcggaatat
     9301 agcgtatatc atattgcata gtcggttaat acttactact ttatacttaa tacttgtttt
     9361 ttatcttttg tttatcggtc gatgtccgga actacatagt ccagtgttcc tccgatggca
     9421 atcaagtcgg caattttcgc tccgcggcaa atcgtgtcga ttgcagcaac aagtggcaat
     9481 cccgtagcac gatagtgcag gcgataaggc atcttgtcac cctgactttc gagaaagact
     9541 ccgaattctc cgcggcttcc ttctacggcg gcataataac tgccttcggg aacgcggatg
     9601 atcggtttca tcttttcctg atacgggcct tcgggaatgt tgtctatcaa ctgctctata
     9661 atcttcagac tctccatgat ttcgtccata cgcaccagat aacgggcgaa acagtctcct
     9721 tccgtataaa caatttcctg gaagtccacc ttgtcatata caccgtacgg tatccgctta
     9781 cgtacatcgc aagcccaacc cgaagcacgg cctgtacccc cggtgcaacc gaatgagatt
     9841 gcatcttcac ggcttaacac tccgacgccc ttcatacggc tctgagcgat aatgttgccg
     9901 gtaaatatgt cgtggtattc gtgaatgata cctctcatat aagggataaa ttcttttacc
     9961 cgcttgacga agttaggatg aaggtcggcc tgtacaccgc cgatggtatt gtagttcatg
    10021 atcagacgtc cgccgcaagt ctcttcaaaa atatcgagaa ttttttcacg gtcacggaat
    10081 ccgtagaaga aagcagtcag tgctccaagg tccatggcga gggcggagta gaacagtaag
    10141 tgagagtcga tacgttgcag ctcatccata attgtacgaa tgtatttgac acggtcactc
    10201 acttcgatgc ccatcgcttt ctcgatgcac atacacaaag cgtgacggtt ctgatgtgcg
    10261 cccagatagt cgaggcggtc agtcaatgcc aatgtctgcg gatatgtaag actctcgttc
    10321 attttctcga taccccgatg gatataaccg cagttagcat cgatcttacg aataatttca
    10381 ccttcaagag aaacgcggaa gcgcattaca ccgtgagttg cagggtgttg cggaccaatg
    10441 ttgactacat actcttcttc tccaaagagt ttcatttctc tgtttttaat cgttccgtcc
    10501 ggattaagtt ctatttcctg tgttgtatcg aacgtctctt cgttagtcat acaaagcgga
    10561 ttatctttct ccggatcatt atctttacgc atggggtatc ctacccagtc attacgtaag
    10621 taaaggcggc gcatatcggg atgccctacg aaaacaatgc catagtagtc gaacacttca
    10681 cgttcgtaga agtcggctat tttccatata tcgctgactg acggaatttc cggtcgttca
    10741 cggtcggtaa cggctgtttt cagtgctatc cgttctcccg taacagtcga ttccagatgg
    10801 tagacaacgc ctaaaccacg gagtttctcc ggtgcgtctt tttcgtctgc tactccccag
    10861 tccataccag tgaggctttc aaggaagtcc atctgttttt catttcgcaa gcgcagcatt
    10921 tcgtcgtgta acgctgcagg gactataaat tgtatttctt gcataattct tcgttcctca
    10981 ttcttcattt cataaattcc ggtttcttct cttttctgtt cgttccacca aagaatttct
    11041 ctattttcac tttgcgttgt agttgcatca tgccgtaata gaaagcttcc gggcggggcg
    11101 gacatccggg gatatataca tcgaccggaa gaatcttatc tactccattc agcacatgat
    11161 aagacttctt gaaaggccct ccgctgacag cacatccgcc tacggcaact acatatttcg
    11221 gatcgggcat ctgatcgtac aaacgtttca gtaccggtgc catcttgttg gtgattgttc
    11281 cgcagaccat gatcatatca gcttggcgcg gactggcacg tgctacttcg aacccgaagc
    11341 ggcccatatc ataacgcgcg gcacccagtg ccatgaattc gatgccgcaa cagctggttg
    11401 cgaaagtaag cggccacagt gaattgctgc gtccccagtt gacaaggtcg tccagaaccc
    11461 caagaaaaac gttcgctcct ccggcattaa gttccttgac caacttttcc aatgactcat
    11521 tgtcgatgaa ctcatcatac ggaattgatt ttattttcgg ttttttggtt atttccattc
    11581 caaagctcct ttcctccagg cataagcaag gcccagaacc aaaataataa agaagaagag
    11641 aatactaacg agcccctgag gtcccatgtc atgcataact actgcccaag ggaacagaaa
    11701 agctgtttcc acgtcgaaca tcaggaacag gatggcaaac aggtagtaac ctacacggaa
    11761 ctgcatccat gatttaccac gcgttggtat accacattca taagcttcaa acttttgtac
    11821 attgtacgaa cgtggtgaaa tagctcgtga aagggctatt actacaccga caaaagcgag
    11881 cgctgtcagt aaaacaacaa ctaaaaatgt aaaattcata atttcaatag ctgtttagat
    11941 tgaatattat atagaaataa acaattagtt tctccacacc cggatgaaac caactgtaat
    12001 gaattgacga ataagataat ggattgtacc gtctaaatga cgatcttcct taaaccatat
    12061 atataatatg taataggatc gtaaaagtac ttgggaatat ggagtgaatg agtctgagac
    12121 gtgttttgct ggcttttgta ttcacggaaa taagtaatca gcaattgcac gcttttatct
    12181 gtagggatgt gtgcaacatc cgcatgactc atatcacaag actgggtaga atagaaataa
    12241 tgaagacgtt caagagcatt atgaacagga tgatcctgag atacgtagca cttctcctgg
    12301 cgatatgtcg ggggggatac tctgcagtta tcttccattg cttcattgga aacaacatgg
    12361 atcagcaaag caagtaccag aaatagtccg tattttaagc tttgtttcat ctttctcttt
    12421 taacggctgc aaatatagga ttaatattca tgttttttgc aaagtcgggg ttacaaaaaa
    12481 gtatttttta acttgcttta tttcaagtcc gtttttattt cagtgctact ctggagaatc
    12541 ttcttctttt atggtatata tccgttctta tttggttaaa agatgtaata aaaagaacga
    12601 tttacgttct ttttgacgaa ttacccaaag aaaattcatt tttttgcaaa ttgtatataa
    12661 cacattgata tgaaacacac actttgcttt ataacaatcc tattgggttc tttgttggat
    12721 ctttatgcaa ataacgagaa tgattctcta ttgaaagttt tagataaagt gatttctgag
    12781 cgtcttgtgt atacagaaaa gaaggaagct actatcaaag agctgaaagc aaaaaagaag
    12841 gaacaaaaga ccttggacga tatgtatcgt ctgaattccg agattctcca tcaatacgaa
    12901 acgtttgtct gcgattctgc ggaacagtac attaatgaga atattgagat cgctaagaaa
    12961 ctggataata aaacctattt gctggaagga aggctgcaac tggcttttgt ttattcctta
    13021 tcggggttgt ttattcaagc taatgatatt ttcaaatcaa tcaattgttc ggatttacct
    13081 agtcatttac aggctttgta ttgttggaat cgcattcggt attatgaaaa cttgattaaa
    13141 tatacagatg atgctcgatt tgccagtgaa tatttgattg aaaaagaggc gtatcgagat
    13201 acagttatga gtatcttgta tgatgcatcg gaagaatatt cgaaagaaag agctataaag
    13261 cttcaggatc agggcaatac aaaagaagca cttaagatac tgactaaaat ttatcaaaag
    13321 gaaaaacctg gaactcacgg gtttgcgatg atgtctatgg gattatcaag agcatatcgg
    13381 ctggtcggag agcatgaatt ggaagaaaag tatcttatat tagctgctat gaccgatata
    13441 aaactggcag tgaaagaaaa tgaggctttg ttgactctag ccgtgaattt atatcataaa
    13501 ggagatatcg atagatctta taattatatt aaagtagcac tgagtgatgc tatcttctat
    13561 aattcccgtt ttaagaatac ggtaatagct cgtattcatc ctattataga aaatacttat
    13621 ttatataggc tggaaaagca aaagcagaat cttcgttttt atattttgct cactagtttg
    13681 tttgttgtgg ctcttgctat cactttgtat tttacttata aacagactaa gattgtttcc
    13741 cgtgcaaaga agaatcttaa tgttatgaat gaagagttag ttgcattgaa caagaatttg
    13801 gatgaggcta atttaataaa agaaagatat gtaggctatt tcatgaacca gtgtgctgtt
    13861 tacatt
//
