LOCUS       c00032_gnlPro..        14757 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JLGHEHEN_32.
ACCESSION   c00032_gnlPro..
VERSION     c00032_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:37:23
            Original ID  :: gnl|Prokka|JLGHEHEN_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14757
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14757
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[278:4757]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      279..4757
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14757
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14757
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(279..3125)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 4.2e-11,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 2.3e-179, bitscore: 586.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3221..3601)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_2"
                     /sec_met_domain="GCV_H (E-value: 2.4e-48, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3672..4757)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_3"
                     /sec_met_domain="GCV_T (E-value: 1.1e-88, bitscore: 286.8,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 4.7e-24, bitscore: 74.1,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLATKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECREVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGTKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAYAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4833..5954)
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(6013..6936)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 1.5e-56, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPFATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7496..8623)
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSTVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGITVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGRDVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCSPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     EKAAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(8620..9732)
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHTQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9729..10745)
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10755..11816
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_9"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-21, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVKEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11935..12312
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12346..12897
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12933..13544
                     /locus_tag="ctg32_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13675..14442
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_13"
                     /sec_met_domain="HAD (E-value: 1.2e-36, bitscore: 116.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYVFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 taagggcaga gaaaaagctc atctgagacg tagctcaacg gatttccaat ccgaaagagc
       61 aaacatatcc agaaaacaat taagcccaaa agcaatatgg gttgaaaaag aaaaaaggaa
      121 catttctccc accccgcttt tcctcccctt tcattttgat gacccatttg ttctcaaaat
      181 agagtgttga cttcggattg gaaatccgat tcttgaacat aagaaaaagg ctgctccaaa
      241 tgaatggaac agcctttttg aaaggaagga tgagattttt ataactctac ggccttggaa
      301 aattcctcca ccgtgtcgca ggtgcagacc agattgcggt ctccgtacac attatccacc
      361 cggcctacat acggccagaa tttgtgaata aggagaccgg agaccggata agccgcttca
      421 ctgcgggagt aggggtgccg ccattcgtcg gcggagacca tttctgcggt atggggcgag
      481 tttttcagga cgttgtcttc cttgtctgcc gtaccgttga taatggccgt gatttccgca
      541 tgaatgcgtt ccatggcttc aatgaagcgg tccagttctt ttttgggttc cgattccgtc
      601 ggctccacca tcagggtgcc cggaacgggg aaggacatgg tggggccgtg gaagccgtag
      661 tccatgagcc ttttggcaat gtcatccacc gtgaggccgg cgtcatgagt gagctgacgc
      721 ggatccagaa tgcattcatg cgccaccagc cccttgttgc cggagtagag aaccgggaag
      781 agatgtccga gtttcttggc aatgtagttg gcgttaagga tggccatttc cgtggcttcc
      841 ctgaggccgt ccggccccat catggagagg tacatccagc agatggcggc gatggaggcg
      901 cttccccacg ccgcagacgc tacggcccct tcttcatggc ccagcgtgag gtgcccgggc
      961 aggaagggta cgaggtgttc cgctacgccg atgggcccga tgccgggacc gccgccgccg
     1021 tgcggcatgg caaaggtttt atgcaggttc aggtggcaga cgtccgcacc aatgcagccg
     1081 gggcaagtca gacctacctg ggcattcatg ttggcgccgt ccatgtacac ctggccgcca
     1141 ttggcatgga cgatgtcgca gagttccttg attgtctgtt catatacccc gtgcgtggag
     1201 gggtacgtga ccatgatgca ggagagattg tccttatggg cttccgcctg ggatttcagg
     1261 tctgccatgt cgatgttgcc tctttcgtcg catttgacgg gcaccacctt gaggccggcc
     1321 atggcggagg atgcgggatt tgttccgtgg gcggaggtgg gaatgaggca gacattgcgg
     1381 tggccttctc cggcgtgctt ctggtagcgg cggatggcca gtagcccggc atattcccct
     1441 gcggcgccgg cgttgggctg gagggatacg gcggcaaagc cggtgatttt cgccagacgg
     1501 tcggacagga cggagagcat ttcccggatg ccttccgact ggtccgccgg aacaaaggga
     1561 tgcagggagt tggcttccgg ccacgtgatg ggaatcattt cagaggcggc gttcagcttc
     1621 atcgtgcagg agcccagagg gatcatggct tcatttagag ccaggtcccg ggattccagg
     1681 cggcggatgt agcgcatcat ttccgtttcg gaatggtagg agttgaaagc cttttccgtg
     1741 cagaaaggcg tctggcgcgt gtggacggga tcccaggcag gagcgtcgca atcgcaggcg
     1801 gcggatgttt ccgcaccagc aagggcggag gccagtgccg ctatatccgc acaggttgcg
     1861 gtttcatcca gagagatggc tgcgtggtcg gcatccaccc tgcggatgtt atacccggct
     1921 tccagggctt tttgcaccat ggcgtccgct tgtccgggaa cggacagcag cagggtgtca
     1981 aagaagtttt tgttttcaat ggcgatgccg gcttccgtga gcgccttgta caggcttttg
     2041 gttttcaagt ggatttccgt gccgatgcgt ttgaggcctt cctggccgtg gtatacggcg
     2101 taaaaggcgg caagcacggc caggagcacc tgggcggtgc agatgttgga ggtcgccttg
     2161 tcgcggcgaa tatgctgttc cctcgtttgc agggccaggc ggtaggccgg gcggcccagg
     2221 gtatctatgg acatgccgat aaggcggccg ggcatgcggc gtttgagagc gtccgtgcag
     2281 gacatgtagg cggcatgggg gccgccgaag cccattggga tgccgaagcg ctgcgtgttg
     2341 ccgatgcaga tatcggctcc gaaggcgccg ggttcccgga tgacggtaag ggccatgaga
     2401 tccgccgcca cgacgcagag cgcgcccgtg gcatgcacgc gggaaaagaa gtccgtgtag
     2461 tcgcagatgc ggccgagcgt gtccggatat tggacaagca ctccggccag atccgcaccg
     2521 atggatgcgg ggtcaaagga ggagcaatct cccacgatga tgttaacgcc ctggaaggcg
     2581 gcgcgggtac ggatgacgct gatggtctgg gggtggcagg tgtccgccac aaagaaggtg
     2641 tttgctttgg ggcgcgcgtt ccggcacatg gtgacggctt ctgctgctgc ggtgccttca
     2701 tccagcaggg aggcgttcgc taccggcagt cctgtcaggg aagagaccat ggtctggaaa
     2761 ttcatgagca tttccagccg tccctgggcg atttccggtt gataaggggt gtaggccgtg
     2821 taccagccgg ggttctccag tacattgcgg aggatgacgg agggagtgat ggtgccgtaa
     2881 tagccctggc caatgaaggt tttcaggagc ttgtttttcc gcagaatgga acggagttcc
     2941 tccagggctt ccgtttccga tttggctgcg ggcaggtcca gcggggcctt catgcggata
     3001 tctgcgggga cgatgtccgc aatgagttcg tcaagcgtcc ggtagccgag gctgtcaagc
     3061 atttcccggc gttcttcccc ctgggggccg atgtgccggc tggcaaaatc tgagtgggta
     3121 ttcatgtggt atctctggct ggtaatagcg tccggccgcg gaacgggcca aacaaaatgc
     3181 cccgggatgg aatcaccggg gcgggggagg gaagaatggt tcaggagcag tattcttcgt
     3241 aatccgtggc gttcatcata tcttccgttt ccgtgggaac gtccaggcgg attttgtaca
     3301 gccagcctgc gccgtagggg tcggagttaa tgagggacgg atcattggaa agctcttcgt
     3361 tcacttctag gatttctcct gaaacggggg tgtacacgtc gctggcggct ttgacagatt
     3421 ccacgacagc gacagggtcg ccggctgcga cggtggcgcc tacttcggga aggtctacaa
     3481 agacgacatc ggagagttcg gcctgggcat ggtcggaaat gccgatggtg ccgatgtccc
     3541 cgtcaatttc aatccattcg tgatctttgg aatacagcag attttctggt acgtcgtgca
     3601 taagatgtaa ttgtttgaag tgagagtgta gtaaaatgag gtgtttgtca gtttattttt
     3661 gcgccgtagt gtcagccttt tttataaaag ggttttttta cgaccacggc tgggaatttc
     3721 cttcccctta cgtcaatttc cagctccgtg ccgaccttgg cataggcggc aggcaggtag
     3781 gccagggcaa tgcccttcat cagcgaagga gagagcacgc cgctggtaag ttctccgatg
     3841 gcttctccgc cggggacgtg cacggcatag tgggcgcggg gaggagctcc cttgccggtg
     3901 tattcaatag cggccagccg acggctgagg ccgttggctt tttgttcccg gagaatatcg
     3961 gaaccgatga agtccgtatc cagcgcgcag aagaatccga gtccggcttc cagaggcgtt
     4021 ttgtccggag agaggtcgga gccgttcaga ggatagcaca tttccagacg caggctgtcg
     4081 cgggcgccca ggccgcaggg tttggttcct gctccaagaa aggcttcaaa ccatttgacg
     4141 ccttccttag ccgggcagaa gaattcaaaa ccatcttccc cggtatagcc ggtgcggcag
     4201 ataatgagat ccgtcccttc cgccgtgatg cgggagattc cattgcgggg gggaagttcc
     4261 acgccgggga tgacgcggga gaatacttct cggcattcgg gaccttgaac agccagcccc
     4321 acgtattcgt cggagtggtt ttccagagtt acgcctgcag gttgatgggc ggaaagccat
     4381 gcgaagtctt catcaatctt ggaggcgttc accactacga agaaggtttc cggttccatc
     4441 cggtacagga tgaggtcgtc aatgactccg gccctgtcat tgagcatgac ggagtattgc
     4501 ccctgcccta cattcagttt gttgatgtca ttggtcagca tggagttcag ccatgctgca
     4561 gcggaaccgc cggctaccgt gaactgcccc atgtgggaga tgtcaaaaat gccgcaggtt
     4621 tcgcgcactg ctttgtgttc gtccagaatg ccggtgtact gcaccggcat attccagccg
     4681 gcgaaaggaa ccattctggc tcccagttca acgtgtttag ttgccagggg ggtggatttg
     4741 acgtctgtat cagtcatgag gcgatgtgaa ggttatgagc aatctgcccc ttatatcagt
     4801 aaaagtcaat ggaattccgg taacgcttcc gtctagacat tgaagcggaa ttcgatgacg
     4861 tccccgtctt tgacgacata ttcttttcct tcgatgcgca gcttgccgtg ttccctcgct
     4921 ccggccttgc cgccgcagga aaccaagtcg tcgtagtgca ctacctccgc ggcgataaaa
     4981 ccgcgttcaa agtccgtgtg gatgacgccg gccgcctggg gtgcttttgc cccggccgga
     5041 atggtccagg cccgcgtttc cttgattccc gtggtgaggt aggtgcgcag gcccagaagg
     5101 tggtacacgg cgcggataag gtcggaaacg ccggagtcct tcacacccag ggattccagg
     5161 aattcgcggg attcttcctc cgagacgtcg atgagttcct cttcaatccg ggcggagatg
     5221 acaatggctt ccgcgttatg gtgttccgct acgtattttt tcacctggga gacgtaggga
     5281 tgggcgtccg ggttggagat ggcgtccgcc agttcgtctt cattgacatt gcaggcgaaa
     5341 atgctttttt tatccgaaag cagctggaaa gaatggagca gcttgcgttc atcgtcgtcc
     5401 agctgcggtt caagggtgag ggcgggattg ccttcgttca ggtggggcag gagtttggtg
     5461 atgagggcca cttcggcctt ggcttccttg tcgccgctgc gtgccttgcg ttcgcgggaa
     5521 gagagtctct tttccatggt ggcgatatcc gccagaatga gttccgagtt gatgatgtca
     5581 atgtcgcgca gaggatccac ggaaccgagt tcatggataa tatcatcatt gtcaaagcag
     5641 cggactacct gcacgatggc gtccacttca cggatgttcg ccagaaactg gttgcccagg
     5701 ccggctcctt ccgaggctcc cttgaccaga ccggcaatat ccacgaattc aataagcgtg
     5761 gggatgattt tttcagaacc ggacatgtcg gaaagaacct gcaggcgggg atccgggact
     5821 gttaccatac ccacgttcgg gtcaatggtg cagaagggat agttggccgc ctgggccttg
     5881 cgcgtccggg tgaccgcatt gaatagagtg gatttgccga cgttggggag acctacaata
     5941 cctgcctgta acataggcag gactgatagc gggtcacgcc gtgaaagtca aataccaatt
     6001 gccgacgggc atttatgcgg cggatcccaa agcccatctg atcaggtttt ccgattccgt
     6061 ccagatacgg gacggatggc agccgaggac gacgacgatg acatggcgcc cgttgacgcc
     6121 ggctgaggaa accaggcagc gtccggcggc gttcgtgtat ccggttttca ttccggtaac
     6181 ccaggggttc tgggtgagca gcttgttggt gtttctcagc agaagcgttc tgccgttggc
     6241 gcgggtaaag gcatattggc gtttgcagat aatattgcgc agttccgggt tgcggtacac
     6301 gtaataggcg cagcgggcca tgtcaatggc agtggaatat tgatccgccg ggaggccgtt
     6361 gggattggcg aagcgtgagt tgtacatgcc catctgccgg gctttggcat tcatcaactg
     6421 ggcgaaacgg ggaacggaac ccgccgtatc gcgggccaga gccaaggcta cgtcgttgaa
     6481 actgcggatc atcatggcat tgagcagttc gcggcgtgaa tagacttccc ccgcccggaa
     6541 tcccagtttg gtggggtccg ccttggtatc ggaaggctgg atgaccactt ttttgtccag
     6601 gctgccgtgt tccatcacga ccatggccgt cacgagtttt tgcgtgctgg ctacctggcg
     6661 gtgctggagg ccgttgtggg aaaagagcac tttgccggta agggcgtcca tgacgcaggc
     6721 gctggcgcag cggggcgtgc gcggggcgct tgaggggatg gctacaggac gtgtggggaa
     6781 attggccggt cgggggaggg catgggaaac cggctgggag agttgtgggg gaacgggcgt
     6841 tgcgaagggg atgtagtcac ttgaatcccc gtacgattgg cagcttgtgg agctcaggca
     6901 aagggagaat cctgcaagaa gggcgaataa acgcatgtct tgttgctaca gtaagaagtt
     6961 tcgttcatca agcccaaact ccgcatttga aagagagccg gacgaaaaag gccgcggatc
     7021 ggacaatccg cggccttttt tctctattaa ctacctatgg aaccaaaaac caccctgaac
     7081 ggattttgaa ttgctttttc catccgtcgg acagatcttg tgaaggatga gactccaggc
     7141 aggagggatg cgttcaaaat atattcgtca acagttcttt ttaagaggtg ttgccgtatg
     7201 agcccgagcc tgcgtccagt aaatatggca gagatttttt ccgaacatat tttgtttttc
     7261 gcgagcatgt aaatttgccg caggcattta aaatgccggg gatgtcctgc cgatatattt
     7321 aatttttgga ataaaattat tgaaggaaag gatttggcga ctgttttaag acgttttttt
     7381 gcatccggat ggaaaggttt ttatacggga gatggacggc gctcccttcc ggttccatgg
     7441 tcagggagag gaggcccgga cctggcgttt tccccggcgg aaaagcggaa tctgcctaaa
     7501 gttccctgcc gttaatggag aaataccctc cggcgtccgg agtaatttgc cctgcaattt
     7561 gcattttggc caaaagcggg gtgatggtat gcgccgcttt ttccagagag gtgcagaggg
     7621 tgtcaatagt attgaaaccc agtctgatgg cgtggagaat ctccttttct tccaaagtgg
     7681 gaagcggtgg ggttgaggct ccggcagggg agcatggcga gaagagaggc agtccctgtt
     7741 ccggaacggc ccagttcatg tcctgcagaa tatcggaggc tccggtagcc aggatggctc
     7801 cgtcccggat gagggcatgg catccgtcgg aagaatgccg gtcaaccggt ccgggaatgc
     7861 aaaaaacgtc tcgaccctgt tcggccgccg ttcgggccgt gatcagggcc ccgctgcgtc
     7921 cggacgcctc caccaccagc gtagcgcggc tccagccgct cacgatgcgg ttgcgcatgg
     7981 gaaaagtggt gcgggagggg ggcaggtcca tcgggaactc ggagactacc gctccatgcc
     8041 cgtccgcaat gcgctgcgcc aagtttctgt tttcccgagg atacagtttg ttgagacctg
     8101 ccccgataac ggcgatggtg cgcccctccg cgtccatggc cccggtatgg gcttccgtgt
     8161 ccacgccgcg cgccagtccg gaaatgacag ttattccggc ttccgccagg tcatgggaga
     8221 tgtttctggc gcaaagcctg ccgtaatggg tggccatccg tgagccgacg acggcaatgg
     8281 agcgttcggc atccgttccg gtccagtttc cccaggagta gaggacaatg ggcgggtctg
     8341 ggagagcacg cagggaggat gggtaggagt cgtcaaaaac cgtggttacc gcggcccccg
     8401 cgttatccgc cagttccagt tccctgtacg ggttgacggt gctccgccaa gaggaaatgc
     8461 ggcaagccag ctgcgccccc acgccgggaa tttccatcaa cagggaggaa ggggattcca
     8521 gaatcagttc cggagaggcg aatacctgca ggagacgcat gattctgaca gggcccaggc
     8581 ccggtatcag gttcagggct atggctgctt cccggggtgt catgaataag gtgtcagttc
     8641 ctggtaaacg tccagatggg cttgaatcat atcctgcata ttgtaagggg aaggaatttg
     8701 ccggggcagg ggggggggct gggtatgcca gcgggccagc aggtccgcca tggcggcggt
     8761 atctcctacg gcgacgttcc cttcaggaag gaaggcgtcc agctgttcct tgactccgcc
     8821 gtgggcgtat ccggctacgg gtttgcccag ggcgagcgcc tccagggttg atttgccgaa
     8881 ggcttccggg cttttggtca gggagagggt gacggaacat gtggaaagga tttccctcag
     8941 atcctggcga tggcctgtcc aggtgaagga ctgggagacg ccggaacgtt ctattgcccg
     9001 caggacctcg tttttatatt cttcttttcc cttctttgct tctcctacaa tgacggcgtg
     9061 ggccgggatt ccctgttcca gaagctgcct gacgaccgga atcagatcca gatgcccttt
     9121 caggcgcgtg atgcggcccg gcaggcacag ggtgaatttc cccttcagtt caggatagga
     9181 catgaaccag cccgtgagcc attcccggga gggggagtag gccgggtgat attggtccgg
     9241 ggaaatagca ttgggtatga ttctgatatg gtccggaggg gtggacggat aatggtcaag
     9301 gatgtagtcc ctgatgcagt tggagacggc gatcacccgc tctcctcggc tcatgatggc
     9361 ggagtaccgg ttgacggagt agaagccgtg aacgctggtg acgaggccgg ggcggtcttc
     9421 cggcgggagc tttttccatg ccaggtagcc tgcccacgca ggaacgcggg aatggagatg
     9481 caggatatcc ggcctgacgg cctgaagcag ggcgcggagg gccccgatgc ggaagagagt
     9541 ggagatgctt tttttgccta tcggcatcag gatgtggcgg gagccttcct tttccagacg
     9601 gggcaccagg cgtccgcctc cggaaacgac gatattttcc acgccccggg aagaaaggcc
     9661 gctgcccagt tccataacga cttgttccac gcctccggat tccatggagg ggacgagatg
     9721 tactattttc ataaggcgcg gagctgaggg aaaaatctgg agaggatgta gtctgctgca
     9781 cggtccgctt ccagaagcgg ggaaccggga gccgtcaggc ggaagttctg ttttttccag
     9841 tcactgtatc cagtaaccat gccttccttt tccagtgtct ccaggccgga caggatgcgg
     9901 gatttgcggc tgccgtgtcg gcgcggtacg gaaaggatgc ctacaggcgc gccggagcca
     9961 agagcctcat ataccatgga gacgctgtcc tggctgaccc aggcggcgga ggcgtgcgcc
    10021 agatgccggg ctacccaccc cggccgggtt tcctccacgg gaacgacggt tagttccgga
    10081 acggccgtcc ggattttttc cgcaaagccg tccggcgtcc ggcgcgaggt ggttagaaca
    10141 aggtgtccgg gggtgtggat gctgatggac gcgagctggt tgagcatgct ttcgtcatcc
    10201 cagtcaaaat ctttgctggg ccctcctatg agaatcagtg tggtatcctt tggtacggag
    10261 ggatccggcc tcatggggtg gagagctccc tgggtgggga agatatccgt atccgtgtaa
    10321 tcgcggccgg aatccaggtc atggcgggga ataaggcaga ggtcgaaaaa ggagcaggga
    10381 agcgtaggct tcatgcagag gacggcccgg gttttgaaat ggtgccgcgc gcagatgagc
    10441 gggatatgcg ttgcatgtcc ggcggaaatg aacagatccg gccgtggaat gtcgctgcct
    10501 gtgacgacct tccggatttt ccccaaaagg gaaagcccct gcaggtctac cgtttccacg
    10561 gttccccccg ctttggagat cagagcctgc gccagcccca gggactggtt gaggtggccc
    10621 tgtttcccat cgctcagaat ccggatgttc atatatgcgg cattatgaag cggcggcggg
    10681 gtgcaggcaa tccaatttcc accggacaga agaaaattct tggtgggagg catgctcttg
    10741 ttcatgattc cggcgtgctg actccggatt cctctgttat taaagattcc ttgtgcgccg
    10801 tgtcccggca gcttggtttt tccggctgcc gggtggcccg tgcggaaaaa agcccgcatg
    10861 cggaaaaatt gtttcaatgg ctggagcgcg gatggcacgc cgggatggag tggatggcgc
    10921 gttccccgga gcggcgcacg gatcctgcgg aagtgcttcc cggatgccgt tccgtcattt
    10981 gcctgtccta tgattatgac agccccggta ggcgcccgga gggggagggt agcatttgcc
    11041 tttacgccca tggaaaggat taccacggaa ttctggagga aaaactggcg gatttgcagg
    11101 agctgctttc catttacggc gggaagcaga gggggtatgt ggactccggc cctgttatgg
    11161 aacgggacca tgcggaggcc tgcggcctgg gctggcgcgg gaaaagcggt ttgatcgtgc
    11221 gcaggaaagg gggctcccgc ttttttatcg ctaccctgct gactacgctg gaactggaac
    11281 cggacgctcc ggtttcaaac ggatgcggca gttgccgccg ttgtgcggcc ctgtgtccga
    11341 cgggcgcaat tatggaaaac ggtcaggttg atgccggacg ctgcctttcc tactggacga
    11401 ttgaacaccg gggggctatt ccggaagaaa tccgtcccct gataggcacg cgcctgtacg
    11461 ggtgcgatac ctgcgtgacg gtctgtccct ggaatggtaa gcctttgccg gacgttgacg
    11521 aacggttccg catgtcccgt ctgctggctt ccattcccct gcgtggtctt ctttccctgg
    11581 atgccggcgg ttttgcggcc ctgttccgga attccccgtt gaaaaggctc aagagggaag
    11641 ggctgctgcg taacggctgc gttgtgctgg ggaatgcggg gactccggat gacattgatt
    11701 ttctgaaggc gctttacggg gagtctcctc tggtgaagga acacgcttcc tgggctgtgg
    11761 agcgcatcct ccgccgccac gggcggcatg catcttcaag cggtgcaaga gattaaaaat
    11821 agaaaaaatg atgttttggt cttgtcaaaa cctcaattta tggtatccat cttgccccaa
    11881 gcaatagctc tgcgcgaggc agagaaaaat aacagctagc aaatccaatc cattatggca
    11941 cgccttttcg gtacagaaat acccaacgag aagcgcatcg aggcttccct tccgtatatt
    12001 tacggaattg gtcgctcgac ttctaagaga atcctggaac aagcaggcat caatcccgac
    12061 atccgcacgg gacagcttac cgacgaacag ctcacgaaga ttgttcaagt aatcaccacc
    12121 gacggcattt tgattgaagg tgaccttcgt cgtgaaaagc aatccattct caagcgtctg
    12181 acctccatca actgctatcg tggtcagcgc caccgccgcg gccttccggt acgcggtcag
    12241 cgtacccgca cgaatgcccg cacccgtaaa ggcaagaaga agaccgttgg cgcgcaggcc
    12301 aagaagaagt aatccgccaa cctgaacttt taatatagct ttactatggc tagcgaagaa
    12361 atcaccaacg aaaccgccga acagcctgtg gaagcggcag cttccgctcc cgtcgctgaa
    12421 actccggccg ccgctgtttc cgctcctgaa gaaatcaaga agcccgaacc ccgcaaggat
    12481 atctttgcgg aacttggtct gggcggcgat gatgacaagc ccaaaatcct gaaggccaag
    12541 ggcagcaaaa acgtttccac gggcgtggtt cacgtttcct ccacgttcaa taacaccgtc
    12601 gtaactgtga ctgaccagcg cggcaatgtc atcggctggt cctccgccgg caagatgggc
    12661 tttaagggtt cccgcaagag cacggcctat gccgggcagg tggtgtgcca ggacgcctgc
    12721 cgccaggcca tgggtcacgg cttgcgtgaa gtggaagtgc gcgtaaaggg gcccggttcc
    12781 ggtcgtgaat ccgccgtacg tgccgtgcag acgatcggta ttgaaatcac ctccatcaag
    12841 gacgtgaccc ccatccccca caacggctgc cgtcctccga aggcccgccg cgtctaattg
    12901 agaatctttt acctatatag atctaatata tcatggctcg ttataccggt ccccgcgata
    12961 aagtgtcccg ccgttttggc gttgcccttt tcggttccac caaggctctt gaaaagcgcc
    13021 ccttccctcc cggccagcat ggcatgcgcg ccggccgcaa gaagaaatcc gactatggcg
    13081 tgatgcttgc tgaaaaacag aaactgcgtt tccagtacgg tgtgcttgaa ggccagttcc
    13141 gcaagtatta tgcagaagcc gcccgccgcc gcggcattac cggcgatatt ctgcttcagc
    13201 tccttgagct tcgtctggac aatgttgtgt accgcctcgg cttcagcaat acccgtgccg
    13261 gcgcccgtca gcttgtttcc cacggtcaca tcaccgtgaa cggcaagaag acgaatatcg
    13321 cgtcctactc ctgccgtccg ggcgacgtca ttgccgtagg cggcaaggct tcttcccagc
    13381 agctggttac ccgtttcctt gacctgactc aggctactgt ggttcctgac tggctggaat
    13441 gcgaccgtga caagctcacg ggcaagattg cccgcgtgcc ttccaaggaa gagattgctc
    13501 ccatcgtcaa cgagcagctc atcgtggaat tttactcccg ttaatcttat ttccttctgg
    13561 atttgcttca aaaccccggt tgcctttcgg cggccggggt tttgggcatt caggaggagg
    13621 ggcatggaag agttgggtgt tgagagttaa gggaagcggg tataggatga aagcatgacg
    13681 gacgattgga aaaaaagagg cgcagcgctg tttgatatgg acggcacgct ccttccctgg
    13741 gatacgcaat atgttttttc ctgttttgtg gtgaggcgcc atccttggag acgcttgctg
    13801 atttttcttt tcctggcctg tattccgctc tatattttga gaatatggga tgagaaccgg
    13861 atgaagaggg cttatctcat gtatttgtgg gggcttcccg ctgaaacggt gcgggaatat
    13921 ggacggaagt ttgccgagat ggcgcaggaa tggatttatc cggagctgaa ggagcggctg
    13981 gcagggtatc ggaagaaggg ttatttgtgt ctcatggttt ccgcttctcc atcattttac
    14041 gtgaagcctc tgggcgaact gctgggattt gacgaagttc tgggaacgga tgtgcttctg
    14101 gaggaacgca tgccggcaat gccggaactg ccgaacggta ataataaggg ggcggtgaag
    14161 gtggagcgtc tgcgggagag gaatgtgctg ccggaacatg gtgttctgga aaacgccgtt
    14221 gcctacagtg acagtgccgc ggatctgccc atgctgcttt cctgcaggcg gagggttctg
    14281 gtgaatcctt ctcctgccct gaaagaagac aggcttctgg atggtgcgga gtgtctgtat
    14341 ccggccaggc cttggaaggg aaggtttggc aagatatgga gaattggatt ttttgtcatg
    14401 gggctggtgg atgtaaataa tgtgaaatca atgacttgct gatttatcaa gagaaaattc
    14461 tttacttttg tgacgaaaat gtttcacttt tcttaacaag gggggaaaaa gcatttttct
    14521 ttccatgtta gcaaatcaac aattaatacc ctaaccaagt aatagtcatg caaaccaaga
    14581 acatcatcag tgttgcggca gttgtggcat cctttgccgg agctgctctt gcgggtactc
    14641 ccgtcaagat tgttgctccg actccggttc ccgctcctgt ggcgacttcc agcccgctgt
    14701 ccggcgatat ttacgccggc tacgcttcca attacacctg ccgcggcatt gtggctt
//
