LOCUS       c00013_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBHCOKAE_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:48:51
            Original ID  :: gnl|Prokka|OBHCOKAE_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 71632
            Orig. end    :: 85321
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[81632:85122]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             911..2056
                     /locus_tag="ctg13_58"
                     /transl_table=11
                     /translation="MPIKRLRPVLAIAADLPLGRLLTSFRNKDRRTIPWIFSLFHALES
                     QEDFDIHWITLSKAVSAPETIRMRNQTIHILPLGSMGRNILTAHFLTVRRIRKTLNDIQ
                     PDLLHVWGVEQAYALAGIAFRGKKLLSYQGALTAYCQRAPQAFLLHMQALWERMAVKHY
                     DLITCESPWACGRVAEIAPHARLSCMEYGVEPSFYHLARKPSPEPSCLFAGTIYELKGI
                     SYLVEAFTHPSLSHVQLFIAGNGALRERLEALSTPNIHWLGSISRAELQQHLSTAWFLV
                     HPTLGDCCPNIVKEARVMGLPVITTEEGGQTQYVQDGVSGYIVPVRNSAAIREAAQKLS
                     VSLDKTMSMGMERHQECRRLLDVKQTVTGCLSRYHTMLYPH"
     CDS             2056..2673
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_59"
                     /sec_met_domain="Hexapep_2 (E-value: 7.5e-15, bitscore:
                     46.7, seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFLIHLLSGIGRLLLRLRGVRTGTGIILSGFPLIKKFPGASIT
                     IGNGVTIHSLTRMNPVLSHHTCLAALSHQASIILEDGCGISGATLVCVNGIRIGRHTLI
                     GADALILDNDMHYPRSGARWGSTLGKPEQGQPISIGEGCFIGARATILKGVTIGSGSVV
                     AAGAVVTRDVPPGCLAIGNPAVNKPLPERLKHPRETQKAICP"
     CDS             2720..3823
                     /locus_tag="ctg13_60"
                     /transl_table=11
                     /translation="MTPQNPTILLPSSREHWIDISRFLAACLIVCVHAPAFSFASLFQL
                     PVFNGRVAFFLILAGYFMGRNNSWNKAFKRGYTLLIPFLFWNIVISFLHPGIMNMGLPE
                     YLCNLAGFRSLFTPDFIPLSINGLTGEPFSPPTWFLRDIILCSLISPILLKLKYPVFVL
                     ILICFSTDWLQYPVPANKITLAPSTVSLFSLGLFLSSIKLAEVKHVYKNSFTPLVLLAV
                     GTGFLLSITNYLSVCQNNPEWNMHKILASYGVWNISWPAVHLNSLCPVFGALLLMALGI
                     WLEKKIPVARKLSNYAPACFLIFVLHYPLIMLIPSHIWKQSFFAPFVLIPAIIFLIVAF
                     YLFLRKFFPACLPYVANDRITHVPKKN"
     CDS             3804..4544
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_61"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.5e-10, bitscore:
                     33.9, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPKKIKACILFLLLTVPAALGAVWCAKHAYRYHLAVHPLPYSPE
                     QGALLEKHRQDKRNARLNPHAPVLFLGSSTMEFWLKEGKHSWETWFSPLGCLNLGTRSE
                     TTGNLLWRLNDGLTSPLAPRIIVLYSGVNNLGVQKSLGWTAFQGNVAIVKKIREIYSPE
                     TTAIIVIPPLIAQKGSRMETFRNCLLQHDFGENVHVLPLHFFLPGKDASLYTWDGLHLN
                     ALGYEAISPPLFRFLQQLLSRSSF"
     CDS             4628..5512
                     /locus_tag="ctg13_62"
                     /transl_table=11
                     /translation="MTLFLAGPTGSGKSAVAVELAEMLDAEIVSSDAYQVYRELPILTA
                     APSPADRERVPHHMVSIIPVQRNWNATEHYHRAMRCMEEIHARGKIAIVTGGSGLYFKF
                     LSHGLSEAPPGDAALRAAFANCSTEALYARLSSLDPEGAASTDASNRRYVERNLEIVLA
                     GGKPLSFWKRNWLTPPRGPGWVISRDVPELDERIAHRAARMMQEGAVEETASLGPCSAT
                     AERTLGLALIRSMLRGEISRENCQGQLALATRQYAKRQRTWLKREQWLRKLPASPSDSP
                     RALAERIMEELGH"
     CDS             complement(5509..6639)
                     /locus_tag="ctg13_63"
                     /transl_table=11
                     /translation="MCSFHYYAGGGHPSEFILPFQFAAIYGVCRLYRDPDRFVRTGVVF
                     GAGIGMALLLKFNLAAFWFVPFLYVLYRARMTGKAWIFTGSVGGTLLLMLTPCLWYFYS
                     RGALLDLYEGYIVFNAGYGADAVSFKEMCRNYSQWVKRDIMYPSMLMYIVGGAGVILSR
                     MPAREKIYYTAAFLITCMGVQGNGKTHFNHYAQTLIPFAAVGYLVVARMIHVEEVVSRK
                     WRRWLFPLVVAGVMACTFLNCVDFSCRSRAREWMSAFALPDTSDEPGGENACAVLGRHA
                     VWFYCVNGLVPPIRTFTICASDKQGAERERMRQYQEIRRGKIDYVVIAGEYFKPDNTES
                     PSLRAMRDLLSTEYCRERSFFREVTNLDIYRRVKRD"
     CDS             6972..7136
                     /locus_tag="ctg13_64"
                     /transl_table=11
                     /translation="MQYNIHLPYYNETFLYGYGFGIPQSDLEFPNRIWNPSSNEKEAKS
                     IMKPMNNKD"
     CDS             7307..8014
                     /locus_tag="ctg13_65"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPEAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg13_66"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9495)
                     /locus_tag="ctg13_67"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg13_68"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_69"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10751..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_70"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.6e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_71"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.5e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 ccgttttttc tccgctccca tggtgcagct accaatttcc gctctttttt ccgcttcaat
       61 taccctcctt tcttcggcct gaaaaaatgg ctctgctcct tttttcaagt acgcagggat
      121 atcctcaacg tatgccggaa atcaccgtta aaccgtctcg tttttctcga tccttacggg
      181 acactgttca agagctttga ttattactgc gcatccagaa gcaaacttgc ccattactcc
      241 tgcattccca acacattccc ggctctgaaa agaaccgctc cttttttccg ggaaaaatac
      301 ggactttcct ccgcccccgt ttttacctgc cctgccggcg ccagcatgag gaaacggcag
      361 cttctcttca tccgccatgt gaaacgctcc cgtctgcggc atatcatttt tctttttctg
      421 attccccagc acaatgccta cgcggaacaa atggaacaag ccatcgggga tgaccccaga
      481 ttcaggattc tctacaggct cccccgtttg gaagtagaag ccgccattat ggaaagcgat
      541 gccgttttcc tttactctta tcaggaacag cagcccctct ccattctgga ggcgatgtca
      601 tgcggcgttc cctggttcgc tccggacgca ggagctcttt ccaccctgga ggggggaatc
      661 gtcctgaaaa acacttcccc ctccgtgctg ggaaaagccg tggaatcgtt gacggacgaa
      721 aaaacacgca aactactggg gagtaaaggc cgccggcaat gggaagcctg tttcgccccc
      781 gacgcagtaa accaggaatg ggagcaactg cttttttcct ccatccgccc ggaaggaaag
      841 cctccgttcg catcttccat cgtccgggag catttaccca cctgctaacc ttgcctcctc
      901 tttccaatcc atgccgatca aacgcctccg tcccgtatta gccatagcag cggacctccc
      961 tctgggccgg ctgctgacgt ctttccgtaa taaggaccgg cgtacgattc cctggatttt
     1021 ttcccttttt catgctctgg aatctcagga agattttgac atccactgga tcaccctcag
     1081 caaagccgtt tctgccccgg aaaccatccg gatgcgcaac cagaccatcc acattcttcc
     1141 cctgggcagc atgggcagga atatcctgac ggcccatttc ctgaccgtcc ggagaatacg
     1201 caagaccctg aatgatatcc agccggacct cctgcacgta tggggtgtgg agcaggctta
     1261 cgctctggcg gggattgcct tccggggaaa gaagctcctt tcctaccagg gagccctcac
     1321 cgcctactgc cagcgcgctc cgcaggcctt cctcctccat atgcaggccc tctgggaacg
     1381 gatggccgtc aaacattatg atcttatcac gtgcgaatcc ccctgggcgt gcggccgcgt
     1441 tgcggaaatt gccccccatg cccgtctatc ctgcatggaa tacggcgtgg aaccttcctt
     1501 ttaccatctt gccagaaaac cttccccgga accttcctgc ctctttgccg gaaccattta
     1561 cgagttgaag ggcatttcct acctggtgga ggcctttacg catccgtccc tttcccatgt
     1621 ccagctgttc attgcgggca acggagccct cagggaaagg ctggaagccc tgtccactcc
     1681 caatatccac tggctgggca gcatttcccg cgcagaactt cagcagcacc tctccacggc
     1741 gtggttcctg gtgcatccca ccctggggga ttgctgcccc aacatcgtga aggaggcaag
     1801 agtcatgggc cttccggtaa tcaccacgga agaaggcgga cagactcaat atgttcagga
     1861 cggcgtatcc ggctatattg tccctgtccg caacagcgcc gccatcaggg aggccgcgca
     1921 gaaactttcc gtcagcctgg ataaaaccat gtccatggga atggagcggc atcaggaatg
     1981 ccgccgcctg ctggacgtaa agcagacagt aaccgggtgc ctgtcacgtt atcataccat
     2041 gctgtatcca cactgatgaa attattcctt atccatctgc tttccgggat aggccgcctg
     2101 ctgctcaggc tcaggggggt gcgcaccgga acaggcatca ttctttccgg atttcccctc
     2161 attaaaaaat tcccgggagc gtccatcacc atcggcaacg gagtcaccat ccactccctg
     2221 actcggatga atccggtact ttcccatcac acctgcctgg ccgccctttc ccatcaggca
     2281 agcatcattc tggaggacgg ctgcggcatc agcggagcca ccctggtctg cgtcaacggc
     2341 atccgcatcg gacgccacac gctgatagga gcagacgcgc tgattctgga caacgacatg
     2401 cactatcccc ggagcggcgc caggtgggga tcaaccctgg ggaagcccga acagggacaa
     2461 cccatttcca tcggggaagg atgcttcatc ggcgccaggg ccaccatctt gaaaggagtc
     2521 accatcggct ccggttccgt agtcgccgca ggagccgtcg tcacccggga tgtgcctccc
     2581 ggctgcctgg ccatcggaaa tcccgcagta aataaaccgc tccccgaacg tctcaaacat
     2641 ccccgggaaa cacaaaaagc catctgccct tgagcatttc ccctgcctgc ctcagggggc
     2701 tccaaaggca gactctttca tgacaccgca aaatcctaca attttattac cctcatcccg
     2761 ggaacattgg attgacatat cccgattcct cgcggcatgc ctgattgtat gcgtccacgc
     2821 gccggccttc tctttcgcca gcctgttcca gcttccggtt ttcaacggcc gcgtggcatt
     2881 tttcctgatt ctggcaggct atttcatggg ccggaataat tcctggaaca aagcgttcaa
     2941 acggggttat acgcttctca ttccctttct gttctggaat atagtcatct ctttcctcca
     3001 tccgggaatc atgaatatgg gactgccgga atacttatgc aaccttgcag gcttccgctc
     3061 ccttttcact cccgatttta ttcctctttc catcaatgga ttgacgggag aacccttttc
     3121 ccctcccaca tggtttttga gggatatcat tctctgttcc ctcatttccc ccatcctgct
     3181 gaaattgaaa tatccggttt ttgtcctgat cctgatctgc ttcagcacgg actggctcca
     3241 ataccccgtg ccggccaaca agattaccct tgctccatcc accgtctccc tgttcagtct
     3301 gggccttttc ctgtcttcca tcaaactggc tgaagtaaaa cacgtttaca aaaattcctt
     3361 tactcccctc gtcctgctcg ccgtaggaac cgggtttctg ctcagcatca ccaattactt
     3421 gagcgtttgc cagaataacc cggaatggaa catgcacaaa atactggcat cctatggagt
     3481 atggaatatc tcctggccgg ctgtccattt gaattccctc tgcccagtct tcggggcgct
     3541 tcttctcatg gcccttggaa tctggctgga aaagaaaatt cccgttgcca gaaagctgtc
     3601 caactatgct cccgcctgtt tcctgatatt cgttcttcat tatcctttga tcatgctgat
     3661 cccctcccac atctggaaac aatccttttt cgctcccttt gtattaatac cggccatcat
     3721 tttcctgatc gtcgcattct atcttttcct gagaaaattc ttcccggcct gcctgcccta
     3781 cgtcgccaac gaccgcatca cccatgttcc caaaaaaaat taaggcctgt atcctctttc
     3841 ttcttttaac cgttccggcc gcattaggcg ccgtctggtg cgccaaacac gcctaccgct
     3901 accatttggc tgtccatccc cttccctatt ccccggaaca gggcgccctg ctggaaaaac
     3961 accggcagga caaacgcaat gcccggctga atccccatgc ccccgtgttg ttcctgggtt
     4021 cctccaccat ggaattctgg ctgaaagaag ggaaacattc ctgggaaacc tggttttccc
     4081 ctctgggatg cctcaacctg ggaaccagga gcgagaccac gggcaacctg ctctggcgcc
     4141 tcaatgacgg cctgacaagc ccgctggcgc ccagaatcat cgtcctgtat tcgggagtca
     4201 acaatctggg agtacaaaaa agcctgggat ggacggcttt tcagggaaac gtggccatcg
     4261 tcaaaaaaat cagggagatt tacagcccgg aaacgaccgc catcattgtc attcccccgc
     4321 tcatcgcaca aaaagggtcg cgcatggaaa ccttcaggaa ttgtctgctg caacacgact
     4381 ttggagaaaa tgtccatgtc ctccccctcc atttcttcct tccgggaaaa gacgccagcc
     4441 tttatacttg ggacggcctc catctcaacg ccctgggata tgaagccatt tcgcctccgc
     4501 ttttccgctt cctccaacag cttttaagca ggagcagctt ttagggcttc acaggaacaa
     4561 caaactttat ccgccattac tccacgtgat gattgaatct tctccacccc atcaggcaac
     4621 acttcccatg accctgtttc tggcaggtcc caccggatcg ggcaaatccg cggtagccgt
     4681 ggaactggcg gagatgctgg acgcagaaat cgtcagttcc gacgcttacc aggtgtaccg
     4741 ggagctgccc atcctgacgg cggcgccttc cccggcagac cgggaacggg tcccccacca
     4801 catggtttcc atcattccgg tccaaaggaa ctggaatgcc acggaacact accaccgcgc
     4861 catgcgctgc atggaagaaa ttcacgcacg cggaaaaatc gccatcgtca cgggcggttc
     4921 cggcctgtac ttcaaattcc tctcccacgg cctgtcggaa gcgccgccgg gggacgctgc
     4981 tctccgcgcc gctttcgcga actgttccac ggaagcgcta tacgccagac tctcttccct
     5041 ggatccggaa ggagcggcct cgacggatgc ctccaaccgg cgttatgtgg aacgcaatct
     5101 ggaaatcgtc cttgccgggg ggaaacctct ttccttctgg aagaggaact ggctgacccc
     5161 gccgcgcggg cccggctggg tcatcagcag ggatgttcct gaactggacg aaagaatagc
     5221 ccaccgtgcc gcacgcatga tgcaggaggg ggccgtggag gaaacggctt ccctcggccc
     5281 atgctccgcc acagcggaac gcaccctggg cctggcgttg atacgaagca tgctgcgcgg
     5341 ggaaatctcc cgtgaaaact gccagggcca gctggccctc gccacccggc aatacgccaa
     5401 acggcagcgc acctggctga aacgcgaaca atggctccgg aaacttccgg cttccccttc
     5461 cgactctccc cgggctcttg cagaacgcat catggaagaa ctggggcatt aatccctctt
     5521 cacacggcgg taaatatcca agttcgtcac ttctctgaaa aaggatcgtt cccggcaata
     5581 ttccgtactt agcaaatccc gcatagccct cagggaggga gattccgtgt tgtccggctt
     5641 gaagtattct cccgctatca ccacatagtc tatctttccg cggcggattt cctgatactg
     5701 acgcatcctt tcccgttctg caccctgttt gtcggaagcg caaatcgtaa acgtgcgtat
     5761 gggcggcacc aaaccattga cacagtaaaa ccatacggca tgccgcccaa ggactgcaca
     5821 agcattctcc ccccccggtt catcactggt atctggaaga gcaaaagcgg acatccattc
     5881 gcgggcgcgg cttctgcatg aaaaatccac gcaattcagg aaggtgcaag ccatcactcc
     5941 cgcaacaacc agaggaaaaa gccatcggcg ccactttcgg gaaacaacct cttccacatg
     6001 gatcatcctg gccaccacca ggtatcccac agcagcgaag ggaataagtg tctgggcgta
     6061 atggttgaaa tgcgtctttc catttccctg gacgcccatg caggtaatca gaaaagcggc
     6121 tgtataataa atcttttccc tggcgggcat ccggcttaaa atcacccccg ctcctcccac
     6181 gatgtacatc aacatgctag gatacatgat atcccttttc acccattggg aataattccg
     6241 gcacatctcc ttgaacgata ccgcatcggc gccgtaaccg gcattaaaaa caatgtatcc
     6301 ttcatataaa tccagcaacg cgccgcggct gtaaaaatac cagaggcagg gcgtcagcat
     6361 caacaggagc gttcctccca cgcttcctgt aaaaatccat gccttcccgg tcatccgcgc
     6421 acgatacagg acatacagga agggaacgaa ccaaaaagcg gccaagttga atttcaacag
     6481 aagcgccatc ccgatgcccg cgccaaacac cacgcccgtt cttacgaagc gatcgggatc
     6541 ccgatacagg cggcacactc cataaatcgc ggcaaactgg aaaggcagaa taaattcgga
     6601 gggatgacct cctcctgcat aatagtggaa actgcacatg gaataaagga tgagcagcga
     6661 aacgataaac gctttttttc cagatacgaa gagaagggcc gccttgtaac aaaagatcat
     6721 ggaggccgtc actgcgaata cctcaagaac gaatacaagc cagtaagaac cacacaaggc
     6781 gtaggaaaag ccatatatca aaaaaatgaa gggccccttt tgatcaaaca aatcccgata
     6841 aggcatcaac ccttccatca ttccgcgtcc catgagatga taaataatgg gatcacaact
     6901 tacgggaatt tcataatagg gagacacata actggaataa taacaaatca gaaatgagaa
     6961 aatagaccac catgcaatac aacatccatt taccctatta caacgaaaca tttttatatg
     7021 ggtacggatt tggaattccc caatcggatt tggaattccc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gactgacccg
     7141 tcatcttgac aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaaca
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagca
     7261 caagtacata cattgaacct tgaatcattt tattaagata ctgaccatga ataaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctgagcgct accgcggcta cctctctgct
     7381 ggatagctcc atcgtgggat attcggactt tgcctcccaa acggcggatt tcggcaccct
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggataacctt
     7501 caacggatac ggtgccaaca accgcgacgt tatgtctgtg acgatggttc ttgacctgtc
     7561 caaaatcaac actccggagg cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 caacgggccc gtcgttgaca ccccgctggg cacggaaggt tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggcgacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcagct
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 ggccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatggca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagtggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gatggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ctggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga gaccgtactt ggaaatgccg
    13681 gacgaaacc
//
