LOCUS       c00004_gnlPro..        14147 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JGDKEKFH_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:58:18
            Original ID  :: gnl|Prokka|JGDKEKFH_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14147
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14147
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[657:4147]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      658..4147
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14147
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14147
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(658..1425)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Fer2_3 (E-value: 6.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2e-10, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1466..3424)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.1e-53, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3446..4147)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="SucD_FumR (E-value: 7e-13, bitscore: 42.0,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4348..4620
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDNTVPETAAAKAACGAPNLSK"
     CDS             4653..5438
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5472..5705)
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6134..6841)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNMDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             7136..7876
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(8094..8387)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MQSPSTAAASSGNIVDATSVIRADDGKEYEVLGMGPIAVLPKYQR
                     RGNRTANNMYAAARQVCELQRGSLSGLKGRYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(8341..8541)
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8555..9760)
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9784..10530)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_12"
                     /sec_met_domain="adh_short_C2 (E-value: 6.2e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10659..11177)
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(11241..12851)
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12974..13681
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
     CDS             complement(13891..14019)
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MKNIAILAIAGAACLVASCSQQQQQQQTTAPAPAPVVQAKGK"
ORIGIN
        1 cctccatgcc ccgcctgccg gggctgccgc cggctccaaa gtaccatttc cggtagccgg
       61 gaacggcaga acgatgggcg gaggaggaac gatgaggcgg attcatcagg tattcaagag
      121 tcgggggtaa tgaaggaagc gagggggccg ccctttcctg atcgttttat caatagtatg
      181 atctgaagtc ggtgtcgata gaattttatt tgtatgtttt tgatttttta taaaagatgg
      241 tcattatttt acacgaaaag ataatattat aattcttacg ttcagtgcat tcccttaata
      301 gacatcaatg ttgtctgttt gttagaaaat gttttcctct catgctgagc ccttgacagg
      361 aggccatccc ttccgggcat cagtctaatt cctgtaatca atgtttcttt ctctcgaaga
      421 aagatggggg ccgtcgctgt cggaaggggg cttgcttagg tttcgtccgg cattgccaag
      481 tacggtctcc tggattactg ggtgccttcc ggtgtaacaa ttttttacgc tgcgcgacga
      541 tgaggaagca actgtctggt attttattcc tggttcaagg aaatctggta atgaaaaaac
      601 tcccgacagc cgatgccgcc gggagttttt acagagcgtc ttaagaagga atcttcttta
      661 gaaacagagg ccttccttgg cgttggcccg catgaagtcg cggttgaggc gggcgatgtt
      721 gtccacgctg atgcctttcg ggcaggcggc ttcacattca tactggttcg tgcagttgcc
      781 aaagccttcc gcttccatct gcttcatcat ggccaggacg cgcttggaac gttccggctg
      841 gccctgcggc agcagattga gatgggcgat cttggcggag gtgaacagca tggcggaagc
      901 gtttttacag gaggccacgc aggcgccgca gccgatgcag gcggccgcgt caaaggcggc
      961 gtccgccttc actttttcca cggcgatgtt gttggcgttc ggcgcggaac cggtacgcac
     1021 gtcaatatag cctccggcgg cgatgatgcg gtccagggcg gagcggtcca ccatcaggtc
     1081 ccgcaggatt gggaaagcct tcgcgcggaa gggttcaatc cagacggtat cgccgtcctt
     1141 gaacttgcgc atgtgaagct ggcaagtggt cacctggcgt tccggcccgt ggggaatgcc
     1201 gttgatggtc agggagcaca tgccgcagat gccttcccgg cagtcgtggt caaaatggat
     1261 gggttccttg ccttccttga ccaggccttc attgacgatg tccagcattt ccaggaagga
     1321 ggcgtccacc ggaatgtcct tggcggcata ggtctcaatg cggcccttgg cttcccggtt
     1381 ttcctggcgc cagaccttga gagtgagatt gagtgtttta gccatgttat aatctttctt
     1441 ttgagtgtta atgtattggc tatctttact tgtagctgcg gatggcaagg tgcacgttct
     1501 cgaaggtcag cggttccttg tggagaacag gcaggctgtc cacgccagtg tattcccagg
     1561 cggctacata ggcgtattca tcgtcgttgc gcttggcttc gccgtccggc agctggtatt
     1621 ccacgcggaa gtgggcgccg caggattcct ggcggttcag ggcgtcatag cagagcagct
     1681 gggcgaattc caggaagtcg gccacgcggc aggctttttc cagttccgcg ttgatgccgt
     1741 ccgccgtgcc ggttacgcgc acgttttccc agaattcctt gcggagctgg ggaatgcgtt
     1801 caatggcgtg ggtcaggctt tcttccgtgc gggccatgcc gcagtcttcc cacatgatga
     1861 ggcccagttc ccggtggaag gagtccaccg tcttggtgcc cttcacattc aggagcttgt
     1921 tgatgcgttc cttcacttcg tcttccgcag ccttgaattc cggggcggcg gtggtgacgg
     1981 cgccgggctt ggtggtcgtc aggtaagcgg gcaacgtggc gggaatgacg aagtagccgt
     2041 cagacaggcc ctgcatcagg gcggaggctc ccaggcggtt ggcgccgtgg tcggagaagt
     2101 tggcttcacc gaggacgtgc agccccttca cgttggacat gaggttgtag tccacccaca
     2161 ggccgcccat ggtgtagtgg gaggcggggt agatcatcat gggcgtttca tgggggtcgt
     2221 cgtccgtgat ttcttcgtac atgtcaaaca gattgccgta ttggccgtca atccattcgc
     2281 ggcccatgcg cttgatttca tccgcaaaat ccaggaagac gcccttgccg gtgacggcca
     2341 cgccgcggcc gtcgtcgcag gcttccttgg cggcgcggga ggaaatgtcg cgcggagcca
     2401 ggttgccgaa ggagggatac ttgcgttcca ggtagtagtc ccgttcttct tcgggaacat
     2461 cggaaggctt gatttccttt ttacggattt tttctgcggt ttcacgggac ttgggcaccc
     2521 agatgcggcc actgttgcgg agggattccg acatcagcgt cagtttggac tggtagtcgc
     2581 ccttgaccgg aatgcaggtg gggtggattt gcgtgaagca ggggttggcg aagaaggcac
     2641 cgcgcttgta ggccttgtag gcggcagtga cgttgcagcc catcgcgttg gtggacagga
     2701 agaacacgtt gccgtagccg cccgtgcaga gcaggacggt atcccctgcg taggatttga
     2761 tttcgccggt aaccagattg cgggtgacga tgcccttggc ttcgccgtcc accagcacca
     2821 gatccatcat ttcatggcgg gagaacattt caatgtgtcc cttggccact tccttttcca
     2881 gggcctggta ggcacccagc aggagctgct ggcccgtctg tccgcgtgcg tagaaggttc
     2941 gcttgagctg ggcgccgccg aaggagcggt tgtccagcag gccgccgtat tcacggccga
     3001 agggaacgcc ctgggccaca cactggtcaa taatgttgga ggagacttcc gccagacggt
     3061 agacattggc ttcacgggcg cggaagtcgc cgcctttaac ggtgtcgtaa aacaggcggt
     3121 aaacggagtc gccgtcgttc tggtagttct tggctgcgtt aatgccgccc tgggccgcaa
     3181 tggagtgggc gcggcggggg ctgtcctggt agcagaagca tttgacgttg tagccaagtt
     3241 cggcaagcgt ggcggcagcg gaggcgccag ccaggccgga acctaccaca agcaccgtgt
     3301 acttgcgctt gttgttcgga ttgatcagtt tggactcaag tttgtacttg gaccatttgt
     3361 cctgaatagg gccggaggga attttggcat ccggcatcca gtcgcttacg ggaaaattaa
     3421 tcatgacttt gagaggagtt gatggttatt tgatgatacc cagaagaacc gagaccggca
     3481 cggagatgaa gcccaggcag ataatcgcgc cgtaggcgat ggcgataaag ttgtagaagg
     3541 gccggatttt gcgggaatcg acgcccacag tctggaagat ggactgtacc ccgtggcgca
     3601 gatggctgaa cagcatcaga acggccagga tgtagaaggc ggagcaccat acgttggaga
     3661 atccggtcac gatcatcttg tacacgtcaa aggtttccac cgtaccgtcg gaaataaagg
     3721 tggtgaactg ggcggggtcg tatcccacgc gcagggtgta ctggtacagg tggtagatca
     3781 ggaacaccag gacggtcaaa ccggtataga tcatgtagcg ggaggagagc gttgccttaa
     3841 tggtgttctt gaacacgtag ggttcgcggg ccgcatggtt ttccagcttc agctggatgg
     3901 tcagccagac gtggatgatg aagatcaccg caagccccgc gcggattccc cagagggctg
     3961 cttccggcat ggagtgcagg ccgtgggcgt aggtgttgat ccattcaggg cctccgaaga
     4021 tgagaaggtt gcctgccagg tgtcccgcaa ggaacaagac caaacataac cccgtcagag
     4081 ccacaatgat tttgcggccg atggaggatg tcacgaatgt acatatggtt tttactagtg
     4141 cattcatagg cgctctaatg aaataaatgc gtcttcacag gatgcccggt tcaagcccgg
     4201 atggcaagcc tcttcttgaa tttccggcgc ttttcggatt tttgaaaaac cggggaaaga
     4261 ggttgctgtt tatcagtttg gaatggttat cattttgttg cctgttccgg cttgacgagg
     4321 ctttccgcat aggcgtatcg tctgtgcatg aaaagaagta aaaaggaggt gctggacgcg
     4381 gatttcgcag cggcgcgcgc cggcgttctg gatgtggccg catttctgga ccgggtggac
     4441 cgcggggaag gggaggcgga tttccgctac catgccctga tggatgttct tcccctcttg
     4501 tccgcatccg gccccggacg cgtccgggcc attctggaag ccctttccta cagggataac
     4561 accgtgccgg aaaccgccgc agccaaagcg gcctgcggag ccccgaacct cagcaaataa
     4621 gaatgatggc tttcatagaa cctcatatac atatggtgtg ccgcaccacg gacgaatacc
     4681 gggccatggc gcaggccggc tgcctggcgg taggggaacc ggcgttctgg gccggttacg
     4741 accgttcgtc cgcggacggt ttccgggatt atttcgtaca gcttacggaa tgcgaacccg
     4801 ccagggcggc caagttcggc atggaccatt acacatggct gtgcatcaat cccaaggagg
     4861 cgcaggacgt ggctttcgcg cgggatgtga tgaaactgat tccggagttc attgaccggc
     4921 ccaatgtcct cggcatcggg gaaatagggc tgaaccggaa tacttcccat gaaatgacta
     4981 tttttgaaga gcatctggat ctggcggtgc gcctcaacca gcttgtgctg attcacactc
     5041 cccatctgga agacaagctt aaggggaccg taatgattct ttccgccctg aaaaaccgtc
     5101 cggatctgga cccttgccgc gtgctggtgg atcactgtga ggaacatacc ttcccgctgg
     5161 tgaaggaggc cggttactgg gccgggctga ccctttatcc caccagtaag ctgaatccca
     5221 agcgggcggc ggatattctg gaattgtacg gaatggaccg tgtctgggcc aattccgcgg
     5281 cggactgggg ggattccgat cccctggcgc tgacggccct ggcctgcgag ctgcgcaggc
     5341 gcggtttttc ccggcaggaa acggaacgtc ttctcctgga aaatccggag acattcatgg
     5401 gacagtcccc gaagttccgg aaagtgtcgt cccgctaatt ccgcccgagg cgcggcggag
     5461 ggtacggccc tctagtcccc gtccgggaaa aagacggtga ggacggcgcc caggatgacc
     5521 gccgcgtcat ccagaaggcc cagcctgccg attccgtcaa acaggaattc gtcgggagtc
     5581 aggatgtagg cgccggcggc ggccagaagg catatattcc gtttgttgaa aaaacgcggt
     5641 tctccttttc tgcttttgaa ataccggaac aggcgcagta gcagctgctg tttttgaagg
     5701 ttcatggacg ggaacggggg ataaaggttc aagctcagcc attttcccac tccttttccc
     5761 tgtttcgggg aaggagtctg ttgccgacgg acgaaaccgc agcgatccgg accgtgcggg
     5821 gaaatggatt gctgaaagga tgggctgttc cggatgctga gggaagccgg gctttgcatg
     5881 ctccggttcc ggctgtcccg gcatgggaaa aaggggcgtg tacggaagtg gggcggggcc
     5941 ggaagctctt gaaatgaccc tcccggggga gcctgaatgc catttccccg tcaagtgctg
     6001 gccgtgaggg taccgcagca aatggaagct tttcccctct gttttttcgg cagatgtttg
     6061 aacggataag gaaaaggccg gctcacgatt ttgtgagccg gcctttgaat atagggaggc
     6121 ggacggtaca ggcttatgcc ctgcggcggc gcatcatcag cgcggccagt cccagcaggc
     6181 ccagggaagc cgtggcgggt tccggaatgc tggcgatttc actcatcagt tgaccaactt
     6241 gttcctggga aaggagggag tcgtggatgt agagctgttc gatggattca gccagtcctg
     6301 cgtccatgag aatctgatca atttgctggt tgccgaattt caggccgctg ttggaatagt
     6361 acgtagcgct gtcgccaaaa tagatgcggg tgccaagatc tccggtgact acggaaatgg
     6421 tcagggaccc ttccgtgccc agcggggtgt caacgacggg cccgctgtat gaggtgttgt
     6481 tccataatcc ctggagtttc cggtccatgt tcaggcccac gccccagctt acactgctgt
     6541 ttttggcgtt aaacagagcg gtataggtct ccggagtgtt gattttggac agatcaagaa
     6601 ccatcgtcac agacataacg tcgcggttgt tggtaccgta tccgttgaag gttatcccgg
     6661 ataacgtcag attgctgtcg tcagacgtga tggaaacgga atctttcagg gtgccgaaat
     6721 ccgccgtttg ggaggtaaag tccgaatatc ccacgatgga gctatccagc agagtggtat
     6781 tcgcggtggc gctcaggctc atgccggccg aaagaatcag ggtggataat aatttcttca
     6841 tggtcagtat cttaataaaa tgatgcaaga ttcaatgtat gcacttgcgc ttgaataacg
     6901 aatttggaat ccgcaagcaa ttaaaaatat taagagttag tatattgtat ttataattca
     6961 ttgaaaataa tgatttttta atatctctgg tccttttgtc aagatgacgg ggcaatcttt
     7021 gttattcatt ggtttcatga ttgatttggc ctctttttca ttacttgacg gattccaaat
     7081 ccgattgggg aattccaaat tcgctacaag ttgccatcca aaaggaataa taaatatgaa
     7141 gaaaacactg acatttttaa tcgcgatggg aagctttgct gtttcctcgg aggcagcgac
     7201 cgtttttaat tattacactc ccggtacgga taattacaat agtaccatcc atgggtttta
     7261 tcttggcctg gggtcttctt ccctggctcc ttccgattcc tcttctccct cctccctgtc
     7321 cggagagatc agactggaca gttttacgct gcgcggagcc gccaacaatt tgggcgctaa
     7381 tgtcacttac ggcttcctgg tgctgaatgg ctccgacaat tcggtcatcg gctggagcac
     7441 caatacggga actactgcag cagggattaa tctgacgttc agtttttctt ccctggatgg
     7501 ttctcccctg cttcttgacg cggcattgac ataccgtttc ctggccgtga gccagtccgt
     7561 gatggacttg atgcaggata cgtctaaaac gtatttatat gctgcggggg gaacagccgc
     7621 ccctactgct aacacggaag gagataccgt aacgatcagc ggcggattga ctgctcccgg
     7681 catccgcggc cattatgacg ccgagggagc gcctggtgat tctgtcgtta ttacgggagc
     7741 caacggaacc aatactttca gcttattatc cccgattttc acggaaatcc gaggggaaat
     7801 ggtgccggaa ccagccacgg tttccctggg cctgctggga ctggccgcgc tgatgatgcg
     7861 ccgccgcagg gcttgagctt cctgatggcg aaaaatcggc ggatgagagc tgttcttgcg
     7921 gaacagctct tgttttttat atccagagag gaagaattgc ttatccgtat gcgggattca
     7981 tgccctccgg aaggtacgga atttccgggg gcagggggcc gtatccggtt ttttcggcat
     8041 ggcggcaatt tgctggaaac gtttttgaga cgcagtaccg gaaagctttt tctttaccgg
     8101 aaaatgccgt caaattcggc agcgcgcttt tcgtccatat ggtacacggc agctttcaca
     8161 tagcggcctt tcaggccgga tagggaaccc ctttgcagct cacagacctg gcgggccgcc
     8221 gcatacatat tattcgccgt cctattcccc cggcgctggt atttcggaag aacggcaatg
     8281 ggccccatgc ccagcacttc atattctttt ccatcgtctg ccctgatgac ggacgttgca
     8341 tcaacgatgt ttcccgacga tgcggctgcc gtggacggcg actgcatcca gctccgggat
     8401 gaaggacgga ctgacgcgca tgatatggag caggtaatgt tcatggcagc cggggacgaa
     8461 atagttccag aacgcttctc tcgtgacatg ttccgtttcg gcatggtctg aggattgttc
     8521 cgttcttaat gcaatggtca tgaaaggttg ttctttacgg ctcccccttg gagaaattcc
     8581 agaggcggtg catcgtcata atgtccggaa tgttcatggg gcgcaccacg cggaacccga
     8641 tcatgcctcc gtccgtcagg taccagatgc ttttagggtt ttgaggatcc tgacggttcc
     8701 aggcgggggt gctggcgcgg cgcgcagcgc ttctcaggct gtccgggtcg tcttcccacg
     8761 aaccgccgcg aacgatgtga ggggcgccgg ggatgatgac caaggggtct ttcgcgggca
     8821 agccgctccg tttgccgtag gcatccggaa cgtaagagtc caaaacccat tccgccacat
     8881 ttccgtgcat gtcccggagt ccccacttat ttggtttttt agagcctgtt ttctggtagc
     8941 ggtcattgga gttgttccag taccaggcgt actggtccag agaggcttcc ccgtttccgt
     9001 aagaataggc gccgggggag ccggcccggc aggcgtattc ccattccgcc tccgtgggca
     9061 ggcggtagta atgcccggtc tgggcgctca gccattcgca gaatttgctg gcggcgtggt
     9121 gggacatgga gatggcgggc agaccgtgtt catagccgtg gcccatgccc aggttcatgg
     9181 cggtgtaggg ggcggtaggc tgcgtaacgg agtcccacag ttcgtcatcc ggctgttcct
     9241 ccagaagctg gccgtccttg gcgcgcggac gcccgttttc catgaaggcc gtataaagtt
     9301 cccaggggat ttccgtttcc gagatccaga agggggagat gctcacttta tgctgcggac
     9361 cttcgtccgg tttccggtgc ggctcttccg cgggactccc catgaggaac gttcctcccg
     9421 gtatggcgac catgcgcagg gaagctcccg ccgcgggaac cgtttccgtg taggattcaa
     9481 aacgtgccgg atttccggaa gcttcaatga gctgatggat ttggcgcgtt gtgccgacca
     9541 gctcccggga cggcaggtca tccggaatgg gaagggcagg accggcagcg cggtccagtt
     9601 cccgtttttg cagcgcggat cggctttctc cccactggcg tgcgctggta atgcgcgcgg
     9661 catcttccgt ggccgggcgg ggggaattat tttcttcccg gcacccggcc agcagggcgc
     9721 ttcctcccag aaagcaggaa acaaggaaaa tgccgcgcat ggaatggaga aaaccggaat
     9781 gccctacatc gtcatgcctc cgtcgcaggc aatgacctgc ccggtgatgt aacgggcatc
     9841 gtcagaggca aggaaggccg tcagggcggc gatatcttcc acggaacctt gttctttcaa
     9901 aggtattttc ttaacgattt cttccttgag attgtcggga atggcattgg acatttccgt
     9961 ggagatgaag ccgggagcaa tggcgttgca cgtgactttg cgcggagcga attcctgagc
    10021 cagtgatttg gtgaaaccga tgaggcccgc cttggaagcg gcgtaattgg cttggccgat
    10081 gttgccgacg agaccgatga cggagctcat gttgatgatg cgcccggccg gggatttcat
    10141 gagaacgcgc tggagggcct tgaccgtatt gaacgcgctt ttcaggttgg tgtccagaac
    10201 ggcatcccag tcttcctctt tcatgcggag catcagggag tcccgcgtga tgccggcgtt
    10261 gttcaccagg atgtcaatct gcgggaagtc tttcaaaatg gcggccatgg tttcctgaac
    10321 ggccgcgtaa tccgctacgt cgcaggggta ggccttgcag gaatccggaa attccttgtt
    10381 gatttcttct gcggcccccc cgcagctgga tggactgcgg ctgatcagga tgaccctggc
    10441 tccttccgaa gcgaagcggc gcgcgacggc attgccgatt ccgcggcccg cgccggtaac
    10501 gatggctgtt ttacctgcta acttttgcat gctgcccaca gtaaacccgt ttttcacggt
    10561 tccggcaagc ttgaaatgga cttggccgcg caggaaccca tacggggaag gggcgtgccg
    10621 ggaatgaaaa aagagggggg gagaaacggg gcggggggct actgtccggc ctcttcattt
    10681 tcccggagtg caccgggggg cgccccgtct tcatccggtt ctaccaggtc gctgaattca
    10741 tccgaatttt ccaaaatgtc ctttaaggcg gcggaaccgt aatagcgggc ctcaaacagg
    10801 cgtttgcctt cctgcctgca gcggttgtcc agcatttcca ttcgtttttc cattttttct
    10861 atcaaggcgt cttctttctc cttttccgca tcgttcaatt tatcctgaag ctggaggaaa
    10921 tgccggatgt ccttctgaat gtcctgcagc gttttgacgg cgttgtccgc gctttccttg
    10981 tcctgaacgc ctgccaacgt ctgctggata ttgatggcaa aggaaaaggc ctggttgatc
    11041 agggattccg cggaaggaat tttttccgcc ggagccgctg ctgcggggga agccgttccg
    11101 gcggccgttt caccaaatgc aagagaggct ccggacagaa gcgcagaata taagagagga
    11161 acaagaaaag ccttcatcct gttcttttaa ggcaggatga aatccacggc aaggaaaaag
    11221 gggaaactga aaaaagagcc ttattccgcc gtgatgccgc ctttttcatc gtccagaatg
    11281 cctgactttt ccagatagta gtcatatcca cctgcgtagg cggtgatggt cccccggttc
    11341 acatgcaggg ttttttgtgc cagggaacgg atgaagtgca catcgtggga gatgaagacc
    11401 agtgttcctt cataatgctt cagagcctgc accagggctt ctacggacaa aaggtccagg
    11461 tgggtggtcg gctcgtccat cagcaggagg ttgggcggat ccaccaggaa tttgaccagg
    11521 ctgagccgcg atttttcccc gccggaaaga acgctgacgc gtttttccac atccagcctc
    11581 cggaacagga aggaacccag gatggaacgc gcttcttcct cccggatttc agcgctgcat
    11641 ttcatgattt cctccagcac ggtattttcc ggattcaggt tttccgttcg cgcctgggag
    11701 aagtagccga tgcgcgtcgt ggtaccggga gtgcgttgtc cggagtcaat ggggatgatg
    11761 cccgccagaa ttttgagaag agtggatttg cccgcgccgt tcgggcctac aagaacagtg
    11821 cgctccccgc gttccaccag caggtccagg ttttcataaa ccctgcggtc accataggat
    11881 tggcagactt tttccagctc aatgactttc tgggtgctgc gcggaggctg ggggaagttg
    11941 aatttaaata ctttcctgcg ggctaccggt ttttgaatga ttttcatctt ttccagctgc
    12001 ttgatgcggc tctggacttg cccggctttg gaattgatgg agcggaaacg gtcaataaat
    12061 tcctgaatgt gcgctatttc cttctgctgg ttgcggtagg ccgcctgaag ctgctcgaag
    12121 cgcacgtcct tttgttggag gaagtccgag taattgccgc ggtattccac cagttcttcg
    12181 ttgtcgatgt cgtacacgct ttccaccagc tcatccatga aatcccggtc gtgggaaatc
    12241 atcaggatgg ctccggggta gtttttcagg tatcgctgga gccacagcag ggacaggagg
    12301 tccaggtggt tggtaggttc gtccagcatc aggaggtccg gctccaggac aaggagtttg
    12361 gccaggtacg cgcgcatgat ccagccgccg gacatttccc gggcggggcg atggaagtcg
    12421 ctttcccgaa aggccagccc tttgagaatt ttcttggctt tgggctccag ctggtaaccg
    12481 ttggcggcgt tgaaagtgtc aatggcttcc gcgtattccg gcgtatccgt tttgttggcg
    12541 ttttccgccg tccggatggt gtggatggcc tgttccattt ccggcgtgat gcccagggcg
    12601 atttccagaa cggtttcatc cttcggttcg ctggcttcct ggggaagata gcccacgatg
    12661 gcgtattcat ccatgctgat ggagccttcg tccggcgtgt cttctcccag aatcatgcgg
    12721 aacagggtgg atttgcctgc tccgttgggg ccaaccagag ccacccgttc cccccagtta
    12781 atggtcattt ccgtttccct gaacaaggtc cgtccggcgt gggattttgt gagatttttg
    12841 atcgtcagca tggtgaagag aggatgtatt ctaccgggat ggaaagggga aggcaagagc
    12901 cgtcagggcg gaggcaggca tttttgaaag ctttactgga tttttacgcg tagtctgcta
    12961 gccttggcgc gccatgccga ccacgcagac attcaggctt ttgcttgctg ccgccctttt
    13021 gtgcggatgg agttcctgct gtactcctcc ggcggaggat tatatacaac aaacttacgt
    13081 gcagcagcaa atgtccgggc tggctaatgc cttcctggcg ctgctgccgc cggatcaggc
    13141 ctctcttccc gctgccggag cggaggccag gtggctggcg gacacggccg tggtccagtc
    13201 cgcagcgatt gcccgggaca acaggactgt gctgtttggc tggctgaaca atattctggt
    13261 caattccaac ctgcgcgaca gggggctgtg ctggcaggtc cagcaggatt tgtaccggga
    13321 cctgcgccgc cgccccgtga agtatttccg catagggctg acgattcgag accgaggaac
    13381 gggcagggag cacagttgcg tgtatgtcaa tgccgcgggg aagggattgc agggctccat
    13441 tgttctggat gcctggaaga actgcgggca tctggtgacg ctgacccaga aggaccggga
    13501 aggcggcaaa tgggaggagg actggcggga accatttgtt tccaaggcct ttccggaggg
    13561 ccattcctac ggcatggaac atcacctggt ctggcccggg tgggccagga aacgccccat
    13621 tctggttcag cggatattcc agtccgatca gcagaatgag gcgaaggcgg ccgctgaata
    13681 aaggggaagc ctgatccggc aggaaccggc acacggtgct gcgccgcggc ggtttgcggt
    13741 atcctccgtt tttaaggaaa atcccggcga atcggcaaat ggcggaggga atccggactc
    13801 agggcaaata aaaacgcact cagtgcgtac accgagtgcg gattaattgg ataatttgct
    13861 agtgttgcag ggcaaaaccc cgctgcaaac ttacttgccc ttggcctgca caaccggagc
    13921 gggagcagga gcggtggttt gctgttgctg ctgctgctgg gagcaggaag cgaccaggca
    13981 agcggcgccg gcgatggcga ggatagcgat gttcttcata attcgaatta aatacagtgt
    14041 ttgttaacta ctggaacctc cgcatccacg gaggtttgct ggcaccaatg taaatggtgg
    14101 caagtagaaa tcaagagatt ttcttgttcc atgtcacggc attacag
//
