LOCUS       c00109_gnlPro..        14809 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGPEONJI_109.
ACCESSION   c00109_gnlPro..
VERSION     c00109_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:54:59
            Original ID  :: gnl|Prokka|KGPEONJI_109
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14809
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14809
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6261:9819](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(6262..9819)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14809
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14809
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             3..521
                     /locus_tag="ctg109_1"
                     /transl_table=11
                     /translation="WPGELGNIDVKSCIKKAIDASTRFYYNVNKTMSYNESSLPSILYV
                     QAKAKAPELDEDHLADYEELAANKFASLTSTKDKLKFIFDQKFCHMNIMNPYEIYNEAR
                     RLVKDFDGELPFVSTPNVVFQERMFYPSSELTNNGDNFAKVAHKNTYDTPVWWTGRTTP
                     AENHNGNAL"
     CDS             628..1170
                     /locus_tag="ctg109_2"
                     /transl_table=11
                     /translation="MKSINVILYWVIVMVIGLSACGDDDEKTIPAHTEEEKIWIADNQK
                     YFQEKKEDVEDDGQLLYQRLVVDEDTLLYRVLETSQIDSFPKIDADVKVSMLGVIPVSQ
                     TVIVGNKDGNPIDQTLKLDSPNLIKGLAALLPKIRKGERVDAIIPYQLGYGDRNYSNPY
                     IPLCSTLQFTFTVKSFD"
     CDS             complement(1237..2235)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_3"
                     /sec_met_domain="Peptidase_M20 (E-value: 5.2e-12, bitscore:
                     35.7, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTGLFVASVMLSTTLWAQSPVEKGLNTINKENAEAYIGFLASD
                     ELEGREAGFQGGRIAAEYIVSNLKTMGIAPLNESYYQPFEAYNKERQKRGRFQVHPDSI
                     AQLKQGVHQKLSMRNILGKIEGKNPNEYVIIGAHYDHLGFDPMLDGDQIYNGADDNASG
                     VSAVLQVAKAFLASGEQPQRTVIFAFWDGEEKGLLGSEYFVQNCPFLKDIKGYLNYDMI
                     GRNSNEVVPEQVDYFYTEANKAFGDWLKNDIKKYNLNLKPIYHPWDKPVGGSDNGSFAK
                     RGIPIIWYHTNGHPDYHMPGDHVEKINWDKIVDITKASFLNMWNLANEKKY"
     CDS             complement(2452..2610)
                     /locus_tag="ctg109_4"
                     /transl_table=11
                     /translation="MMTSRNEENLRTLAMLRYQADRYQSMRNGTMSQRVNAEIRRLLEE
                     MGANAKN"
     CDS             complement(2800..3342)
                     /locus_tag="ctg109_5"
                     /transl_table=11
                     /translation="MIDELLEYNRGFVDKKGYEKFITNKYPDKKIAIVSCMDTRLIELL
                     PAALGIKNGDVKIIKNAGAIISHPFGSVIRSLMVAIYELGVVEIMIIGHSDCGAQHMDS
                     DEMIEAMKKRGIPAERIDMIRYCGIDFKYWLRGFDSTECSVKDTVEQVRNHPLIPTDIT
                     VRGFVINSVTGELTEVE"
     CDS             complement(3396..4172)
                     /locus_tag="ctg109_6"
                     /transl_table=11
                     /translation="MVKAIFFDIDGTLVSFKTHEVPRSTIDALDILRKKGIKVFIATGR
                     HYSSINNLGDLKFDGYVTLNGGYCFAGEDKVIYKHSIPDRDIDALIRYLETEESFPCAF
                     VQEKEIFMNYKDETVEEIFNMLNFPEPPIRPLSEMKGKTVYQLVSFFTAEQEKKIMSIL
                     SHCESTRWNPLFTDVVPAGSSKRIGIDKMLEYFKIPLKECMAFGDGGNDIAMLQHAGIG
                     VAMGNADDDVKQYADYVTDSVDEDGIFKALKFHNII"
     CDS             4282..5316
                     /locus_tag="ctg109_7"
                     /transl_table=11
                     /translation="MEYRQLGGSGLYVPVLCLGTATFGGTNGFEGWGHTQVDEARRMIN
                     LCLDAGVNLFDTADAYSDGLSETILGKAVEGLRNKLLISTKATFNLNPEGRNAMGSSRF
                     HLIEACEASLKRLNTDHIDIYHMHGFDANTPVEETLRALDDLITAGKIRYIACSNFSGW
                     HLMKALSVSERYGWSRYVAQQVHYSLLNREFEWELMPLGIDQKVGSIIWSPLSAGRLGG
                     RYRRNNPIPADGRVARGGSPIPDEATSYERLYNIMDVLDEIAEETGHSVAQCALNWLLQ
                     RPTVSSLIIGASTEEQLKQNLEAVGWNLTPEQVKRLDNASQVTPIYPYWHQAQFPFLNA
                     QIQF"
     CDS             complement(5496..6152)
                     /locus_tag="ctg109_8"
                     /transl_table=11
                     /translation="MAKNKSKQNQFQLLSPEKYIRLKARNLPIEVCYVSDDWKDERGAV
                     AEVIVVRRHAGGNYTFGVYVVDTLCLGVKHSVYRFNVPPDEYDDFVERTATDCGIKISY
                     NEAHNFIYGAIAFAEEFGIKPDKSFALTQYILEEDTEEIPLIEYKYGRGGRPHLVAETS
                     LEASKYIPILEESTGGDFGLEILEDRDVFDDDEFDDEFDDDEFDDEYDEEDNKTM"
     CDS             complement(6262..9819)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_9"
                     /sec_met_domain="PFOR_II (E-value: 9.3e-20, bitscore: 60.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.3e-83, bitscore: 268.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 4e-32, bitscore: 101.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.3e-13, bitscore:
                     39.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 4.9e-13, bitscore: 39.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.4e-07, bitscore: 21.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.9e-05, bitscore: 13.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 6.7e-25, bitscore: 76.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVMVQEMQSEGGAAGAVHGSLQAGALTSTYTASQGLLLMIPNMYKIAG
                     ELLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEALENDDLAPLIDQKALAEFRARALNPEKPEARGMAE
                     NPDHFFQHRESSNKYYEAVPAIVEEYMNEISKLTGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLTAQGEKVGLVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKEPGATGE
                     PLYLDVKDCFYGQADAPVIVGGRYGLGSKDTTPAQILAVYENLALPMPKNQFTLGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKYCQAYFSYDS
                     KKSGGFTCSHLRFGDHPIRSTYLVNTPNFVACHVQAYLRMYDVTRGLRENGTFLLNTVW
                     NGEELANHLPNKVKRYFAQKNITVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DLAIEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYTQLTVDPDWANLPDDEVVANNDP
                     AFINEVVRPINAQDGDLLKVSAFKGIEDGTWRQGTAKYEKRGVAAFVPVWDGENCIQCN
                     KCAYVCPHASIRPFVLDAAEQAAAPFNNSLKATGKQFEGMQFRIQVDVLDCLGCGNCAD
                     VCPGNPKKGGKALKMVALEGQLAEAPNWEYCTEKVSSKQHLVDIKANVKNSQFATPLFE
                     FSGACSGCGETPYVKLVTQLFGDREMVANATGCSSIYSGSVPSTPYTTNDKGQGPAWAN
                     SLFEDFCEFGLGMELANEKMRARLTNAMNEIIAADNAPAEAKEVLKAWVENQNDADKTK
                     ELAPQVLAIAEEGITHGCPLSAQIKELSHFLVKRSQWIIGGDGASYDIGYGGLDHVIAS
                     GKNVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRIRKKDLGLMATTYGYVYVAQ
                     IAMGADQAQTLKAIREAEAYDGPSLIIAYAPCINHGLKKGMGKSQQEEADAVACGYWHL
                     WRYNPALEEEGKNPFTLDSKEPDWSKFQDFLKGEVRFASLTKQFPAEAAQLFQAAEDNA
                     KWRLNNYKRLAKQQWGVEE"
     CDS             complement(9852..11030)
                     /locus_tag="ctg109_10"
                     /transl_table=11
                     /translation="VEAFFKTHKYLVEHLHAPVRRGLMDEIDWNDRLIGIKGSRGVGKT
                     TFLLDYAREHFGADNKECLYINLNHFYFTERTLVDFASEFRAKGGKVLLIDQVFKYSGW
                     SKELRYCYDNFEDLKIIFSGSSVMRLKEENPDLSGKVVSYNLRGFSFREFLNLMSGNSF
                     PAYTFEEIIGNHQEIAKNICSVAKPMAYFQDYLHHGFYPFFLEKRNFSENLLKTMNMML
                     EVDVLYIKQIEQSYLPKLRKLLYLLAISAPCTPNVSQLSKEIETSRATVMNYIKYLTDA
                     RLMNMLYPVGESFPKKPSTVYMYNSNLMYPIRPMEVNVQAVRESFFYNQLLKDNTLNEG
                     MKNAHFLVNGKYNFRIEESMKVKNNPDLYYAVDKVEVGEENMIPLWLFGFLY"
     CDS             complement(11218..12237)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_11"
                     /sec_met_domain="Aminotran_4 (E-value: 1.3e-32, bitscore:
                     103.4, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMNWSDLAFGYMKTDYNVRCYYRDGKWGELEVSSSEIINIHMA
                     ATCLHYGQESFEGLKAFKGKDGRIRVFRMDENGKRMQASSRGIKMAELPVEMFEEAVRK
                     VVKLNERFVPPYESGAALYIRPLMIGLGAQVGVKPAPEYMFMVFVTPVGPYFKGGFKPS
                     KVCIMREYDRAAPYGTGTIKVGGNYAASLVAGEIAHEKGYAAVLYLDPKEKKYLDECGP
                     ANFFGIRGNSYITPQSHSILPSITNKSLQQLAEDMGLTVERRPVPFEEIATFDEAAECG
                     TAAVIAPISQIDDLDENKSYVIAKDGKPGPVCEKLYNKLRGIQYGDEPDTYGWVTVIE"
     CDS             12321..13271
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_12"
                     /sec_met_domain="MTHFR (E-value: 2.7e-64, bitscore: 207.1,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKY
                     INITSHHSEYIYKTLPDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDE
                     TEYALIDLNFLGVYDLLLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGST
                     FEANETPFSYGMACYPEKHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVE
                     RCRAEGIDVPIIPGIKPVVFKNQLTVLPKIFRSDIPEPFAAELRKCKNDDEVKAVGVEW
                     CIQQCKDLIAHGVPSLHFYTMMATDSVYKVAKEVY"
     CDS             complement(13494..14360)
                     /locus_tag="ctg109_13"
                     /transl_table=11
                     /translation="VLVLAASPSFVSCGGQRPVRFGVVTDLHYSRREPYGTRYFPQTMD
                     KLKEAMEVFNSSNLDFVIEMGDLKDQDNVSQREQTITYLDEIENVFQSFRGPVYHVLGN
                     HDMDSISKDDFLQHTSNQGDADKKAYYSFAFDNIKFIVLDANYNLDGTPYDKGNFDWTK
                     AYIPKDQIDWLKKELKGNNKPVIIFIHQLLDRFSDISKSLCVSNADEIVPLLEENGNVL
                     AVFQGHHHAGHYSFRNNIHYWTMKGMIEGNLPDNNSFAVVEIDTQNNIHIDGFYNCEDK
                     DLNRFTV"
     CDS             14713..14808
                     /locus_tag="ctg109_14"
                     /transl_table=11
                     /translation="MKYILFITMDLAVYPFLLLIYIVKCIFDKIQP"
ORIGIN
        1 gttggccggg cgagttaggt aatatcgatg ttaaaagctg tattaagaag gccattgatg
       61 cttctactcg tttctactat aatgtgaata aaacaatgag ttataatgaa tcttctctgc
      121 cgagtattct gtatgttcag gcaaaggcta aagctccgga attggacgaa gatcatctgg
      181 ctgattatga agaactagct gctaacaagt ttgctagttt gacctcaaca aaagataaac
      241 tgaaattcat tttcgaccag aagttctgcc acatgaatat catgaatccg tatgaaattt
      301 acaacgaagc tcgtcgtttg gtaaaagact tcgacggaga actgccgttt gtctccactc
      361 ctaatgtggt attccaggaa cgtatgttct atccgtccag cgagttgact aacaacggtg
      421 ataactttgc aaaagttgct cataaaaata catacgacac accagtttgg tggacaggac
      481 gtacaactcc tgcagaaaac cataatggta atgcattgta ataaacatta gcttaatgct
      541 acataaacac aaaggctgtc gagaaacttt ttcgacagcc tttattcact ataaaatgta
      601 ctgcataatt taacaaaatg agtaaaaatg aaatcgatta atgtgatcct gtattgggta
      661 atagtgatgg tgatcggcct atcggcttgt ggtgatgacg atgaaaagac gataccggct
      721 catacagaag aggagaaaat atggattgcc gataaccaga aatattttca ggaaaaaaag
      781 gaagatgtag aggatgacgg acaattgctg tatcagcgat tagtcgtgga tgaagatacg
      841 cttttgtatc gtgtactgga aacgagtcaa atagattctt tccctaagat agatgctgat
      901 gtaaaagttt ctatgttagg agtaattccg gtttcccaaa cggttatcgt aggtaataaa
      961 gatggtaatc cgatagatca gactttaaaa ttggacagtc cgaatctgat taagggcctg
     1021 gctgctcttt tgccgaaaat ccgtaaagga gaaagggtgg atgctataat tccttatcag
     1081 ttgggatatg gggatcgtaa ttactccaat ccgtatattc cattatgctc aacgttgcag
     1141 tttactttta ctgtaaaaag ttttgattaa gcttttaaaa aggagaggtt gtttcacttc
     1201 aaaaattgaa agatcctctc ctttttatat tcaacactaa tatttcttct cattcgccaa
     1261 gttccacata ttcaggaaag aggcttttgt aatatctacg atcttatccc agttgatctt
     1321 ttcgacatgg tcgcccggca tatggtagtc cggatgaccg ttggtgtgat accagataat
     1381 gggaatacca cgtttggcaa aagagccgtt gtcactccct cctaccggct tgtcccaggg
     1441 gtgataaatc ggtttcaggt tcagattgta tttcttgata tcattcttca gccagtcacc
     1501 aaaagccttg tttgcttccg tatagaaata atcgacctgc tcgggaacca cttcgttcga
     1561 attgcggccg atcatatcat aattcaaata tccctttata tctttcagga acggacagtt
     1621 ctgcacaaaa tattcagagc ctagcaatcc tttttcttca ccgtcccaga aagcaaagat
     1681 taccgtacgt tgcggttgct caccggaagc caggaatgct tttgcaacct gaaggacagc
     1741 cgatacgccc gaagcattat catctgcccc gttatagatc tgatcaccgt ccagcatcgg
     1801 atcgaaaccc aggtgatcgt agtgtgctcc gatgataaca tattcattcg gattcttccc
     1861 ttctatcttt cccaggatat tacgcatgga taacttctga tgtacgcctt gcttcagttg
     1921 ggcgatcgaa tcaggatgca cctgaaaacg tcccctcttc tggcgttcct tattataagc
     1981 ctcgaaaggt tggtaataag actcattcaa gggagcgatg cccattgtct tcaggttgga
     2041 gacgatatac tcggcagcaa tccgtcctcc ctggaaaccg gcttcacgcc cttccagttc
     2101 gtcactggcc aagaaaccga tataggcttc cgcattttcc ttattgatag tgttcagtcc
     2161 tttttctaca ggcgactgtg cccaaagggt ggtagatagc atgacggatg ctacaaataa
     2221 acctgttctt ttcattgtat gattgtgttt tacaaattat cggaaatact tagtttcagc
     2281 ttccgatcac aaagatagaa gataaattga agaattgtaa ggacaataaa ataaaaaaag
     2341 gctaatcttc actgatcctc cagtgtcgaa tgcccatctt tttgtctctc accagtctta
     2401 taaaagaccc tggtgaagag aatacatcaa aataatatac tttctttttg tttaattttt
     2461 tgcgttagcg cccatttctt ccaacaggcg acggatttca gcatttactc gctgactcat
     2521 tgtaccattt ctcattgact gataacgatc agcctgataa cgcaacatcg ctaaagtacg
     2581 aagattttct tcatttctac ttgtcatcat aatctttact tttttatgtc tcccacgctt
     2641 ggaagactcg ttaataatta acctaaacct taatcttttc tttttgttta cagtgcaaag
     2701 ataagcactt tttccaaaac tatgctataa aacatataaa ttatttctat ctttacattt
     2761 atttaatcta tagaaataga ttttcagaag ataacctccc tactccactt cggtcaattc
     2821 acctgtaact gaattaatta caaagcctct aaccgtaata tcggtaggaa tcaacgggtg
     2881 gttgcgaact tgttcgactg tatcttttac tgagcattct gtcgagtcaa acccacgaag
     2941 ccagtattta aaatcgattc cgcagtaacg gatcatatcg attcgctcag cgggaatacc
     3001 ccgtttcttc attgcttcga tcatctcgtc gctgtccata tgctgggcac cacaatcaga
     3061 atgaccaatg atcatgatct cgaccactcc cagttcataa atagcgacca tcagactgcg
     3121 tatcacactg ccgaacggat gtgaaatgat tgcaccggca ttctttatga ttttcacgtc
     3181 gccattcttt atgcccaatg cggcaggaag caattctatc agacgagtat ccatacagga
     3241 tacgatggca atctttttat cgggatactt attcgttata aacttttcat atcctttctt
     3301 atctacaaat ccccggttgt attcaagtaa ttcgtctatc atgagtctgt ctttctttta
     3361 ataataacac tagctatata aataacaaca ctggtttaaa taatgttgtg gaatttcaag
     3421 gctttgaata tcccgtcctc atcaacagaa tcggttacat aatccgcata ttgttttacg
     3481 tcgtcgtcag cattccccat agcaaccccg atcccggcat gctgaagcat ggctatatca
     3541 ttaccgccat caccgaaagc catacattct tttaatggta tcttaaagta ttccagcatt
     3601 ttatcaatac cgatccgctt gctgctcccg gcaggtacca catcggtaaa caacggattc
     3661 cagcgagtgg attcgcaatg ggataagata gacatgatct ttttctcctg ttcggcagta
     3721 aaaaatgaga ctaactggta gaccgtcttt cccttcattt cactcagagg acggataggc
     3781 ggctccggaa aattcagcat attaaaaatt tcttccactg tttcatcctt ataattcata
     3841 aagatttctt tttcctggac aaaagcacag gggaaagact cttcagtttc caaatagcgg
     3901 atcaatgcat cgatatccct gtcgggaatg ctgtgtttat agatcacttt gtcttctccg
     3961 gcaaaacaat atccaccgtt cagtgtaaca tatccgtcaa attttaaatc tcccagattg
     4021 ttgatggaac tgtaatgacg acctgttgct ataaaaactt taataccttt cttccgtaag
     4081 atatccaatg cgtcaatggt agagcggggt acttcatgtg tcttaaaact gaccaacgtc
     4141 ccgtctatat cgaagaaaat tgccttaacc atactttttc taataaccta aatttgatac
     4201 aaagataaga ataaataaac acatgcggat ttttatatac ctttgtaagt aagatcttaa
     4261 taacaattta ataggtaagc tatggaatac agacaattag gaggatcggg actttatgta
     4321 cccgtgcttt gtttagggac tgctactttt ggaggtacaa acggtttcga aggatgggga
     4381 catacccaag tggacgaagc cagacgcatg ataaaccttt gtctcgatgc gggtgtaaac
     4441 ctgttcgaca ccgctgacgc atattcagac ggactttctg aaacgatatt ggggaaagct
     4501 gttgaaggac tgagaaataa actgttgata tcgaccaaag ccacattcaa cctgaatccg
     4561 gaaggacgca acgctatggg ttcttcccgc ttccacctca tcgaggcctg cgaagccagc
     4621 ctgaaacggc tgaataccga tcatattgat atttatcata tgcatggatt tgacgccaat
     4681 acgccggtag aagaaacgct tcgcgctctg gatgatctga tcactgccgg aaaaatacgg
     4741 tatatcgctt gttctaattt ctccggatgg catctgatga aggctttgtc tgtctccgaa
     4801 cgctatggct ggagtcgtta tgtggcacag caggttcatt attctttgct caacagggag
     4861 tttgaatggg aattaatgcc gctcggaatc gatcagaagg taggttccat catctggagt
     4921 cctctttcag caggacgtct gggcggaaga taccggcgca acaatccgat accggccgac
     4981 ggacgtgtgg ctcgcggcgg aagtcctatc cccgatgaag ctacttccta tgaacgttta
     5041 tataatataa tggatgtatt ggatgaaata gcagaagaga caggacattc ggtagcacaa
     5101 tgtgcgctga actggttact gcaacgccca actgtttcca gcctgataat cggggccagc
     5161 acagaagaac aattaaaaca gaatctggag gctgtcggct ggaacctgac accggaacag
     5221 gtaaaaagac tggataatgc cagccaggtc acccctattt atccatattg gcaccaggca
     5281 caattcccgt ttttgaatgc acagattcaa ttttagaaag aattgagcta tcccgttccc
     5341 gtgcttgaca cgggatcgca aaggcacaga ccgtttccta taatatcttt tgataccgcc
     5401 agttctcttg cggccccgtg tcaagcacgg ggacaggata gttcactttt gacaaaaact
     5461 gaaccaattc cctctatatt attattgtaa tattcttaca ttgtcttatt atcctcctcg
     5521 tcatattcat catcaaattc gtcatcatcg aattcgtcgt cgaattcatc atcatcaaac
     5581 acatcacgat cttccaatat ctcaagaccg aaatcgccgc ctgtggattc ttccagtata
     5641 gggatatatt tacttgcctc aagagaagtt tcggcaacca ggtgagggcg gccacctctc
     5701 ccatatttat attcaatcaa aggaatctct tccgtatcct cttccagtat atattgcgtc
     5761 aaggcaaaac tcttatccgg tttgatcccg aactcttcgg caaacgctat agccccataa
     5821 ataaaattat gagcttcatt ataactgatt ttaataccgc aatcagttgc cgttctttca
     5881 acaaaatcgt catactcatc cggtggcaca ttaaacctat atacagaatg tttcactccc
     5941 agacacaacg tatctacgac gtaaactccg aatgtataat ttccaccggc atgacgacga
     6001 actacgatca cttccgctac agcccctctt tcatctttcc agtcatcgga aacataacac
     6061 acctctatcg gtaaatttct agctttcaaa cgaatatact tttcaggaga gagtaactga
     6121 aactgattct gcttgctttt atttttcgcc atttgcttgt ttgtttagtt tcgctaaagg
     6181 tacgatttat ttggcttata caaaaaaacg gaaccctctt tcgaagattc cgttttacta
     6241 tttagatgat caaataatca attattcttc aacaccccac tgctgtttag ccaaacgctt
     6301 gtagttgtta agtctccact tagcgttgtc ttcggcagcc tggaacaatt gagcggcttc
     6361 ggccgggaat tgttttgtca gagatgcgaa acgtacttca cccttcagga agtcctggaa
     6421 cttgctccaa tccggttctt tgctatccaa agtgaatgga ttcttgcctt cttcttccaa
     6481 agccgggttg taacgccaca aatgccagta accacatgct actgcatcag cttcttcctg
     6541 ctggctctta cccataccct tcttcaaacc gtggttgata caaggagcgt aagcaatgat
     6601 caatgaagga ccatcataag cttcagcttc gcggatcgct ttcaatgtct gagcctggtc
     6661 ggcacccatt gcgatctgag caacataaac ataaccgtaa gttgtagcca tcagacccag
     6721 gtctttcttg cggattctct taccggaagc agcaaactta gcgattgcac ctaccggagt
     6781 agctttagaa gactggcctc ccgtatttga ataaacttca gtatccaata ccaggatgtt
     6841 aacgttctta cctgaagcaa ttacatggtc aagaccaccg taaccgatat cgtaagaagc
     6901 accgtcacca ccgataatcc actgtgaacg ttttaccagg aagtgagaaa gctccttgat
     6961 ctgtgcgcta agcggacacc cgtgagtgat accttcttca gcaatagcca atacctgagg
     7021 agccagttct tttgtcttat cggcatcatt ctgattttca acccaagcct tcagaacttc
     7081 cttagcttca gcaggagcat tgtcggcagc gataatttcg ttcatcgcat ttgtcaggcg
     7141 tgcacgcatc ttttcgttag ccaattccat acccagaccg aattcgcaga agtcttcgaa
     7201 caatgagtta gcccaagccg gaccctgacc cttatcattt gttgtataag gagtagaagg
     7261 tactgaacct gaatagatag aagaacaacc tgttgcgtta gctaccattt cacggtcacc
     7321 gaacagctga gttaccaact tcacgtacgg agtttcacca caaccggagc aagcaccgga
     7381 gaactcaaac aacggagttg cgaactgaga gttcttcacg ttagccttga tgtcaaccaa
     7441 gtgttgtttg cttgaaacct tttcagtgca atattcccag ttaggagctt cagccaactg
     7501 accttccaaa gcaaccatct taagcgcttt gccacccttc ttcggattac ccggacaaac
     7561 gtcggcacag ttaccacaac ccagacagtc aagaacgtct acctgaatac ggaactgcat
     7621 tccttcgaat tgtttacctg ttgctttcaa agagttattg aacggagcag cagcctgttc
     7681 agcagcatcc aacacgaacg gacggataga agcgtgagga caaacatatg cacacttatt
     7741 acactggata cagttttcac catcccatac aggaacgaaa gcagccacac cacgtttttc
     7801 gtatttagct gttccctgac gccaagtacc atcttcgata cccttgaatg cagaaacctt
     7861 cagcaagtca ccatcctgag cattgatagg acgaactact tcgttgatga aagcaggatc
     7921 gttgtttgct acaacttcat cgtccggcag gttagcccag tccggatcaa ctgtcagttg
     7981 agtatattcg ccaccacgat cgacagcagc atagttcttg ttaactacat cttcaccctt
     8041 ctttccgtaa gacttcacga tgaatttctt catctgttcg atagccagat caacaggaat
     8101 tacacctgtg atgcggaaga atgcagactg aaggattgta ttggtacggt tacccaaacc
     8161 aatttccaaa gcaatctgtg ttgcattgat atagtaaaca gtaatatttt tctgagcgaa
     8221 ataacgtttt accttgttcg gcaggtggtt agccaactct tcgccattcc atacagtgtt
     8281 caacaggaat gtaccgtttt cacgcaaacc gcgagtaaca tcgtacatac gcagataagc
     8341 ctgaacgtga caagcaacga agttcggagt atttaccaaa taagtagaac gaatcggatg
     8401 atctccgaaa cgcaggtgag aacaagtgaa accgccggat ttcttagagt cgtaagagaa
     8461 gtatgcctgg caatatttgt ctgtattgtc accaataatc tttacagagt tcttgttagc
     8521 acccaccgta ccgtcagcac ctaatccgta gaacttagct tcgaacatac cttcaccgcc
     8581 caaagcgatt tcttctttct gaggaagaga agtgaatgta acatcgtcta cgatacccag
     8641 tgtgaactga ttcttcggca tcggcaatgc cagattttcg taaacggcaa gaatctgtgc
     8701 cggagtagta tctttagaac ccagaccata acggccaccc acgataaccg gagcgtcagc
     8761 ctgtccgtag aaacagtctt ttacatccag atacaaaggt tcgccagttg cacccggttc
     8821 ttttgttctg tcaagaactg cgatacgttt tgcagtctta ggaacagctg ccaggaagtg
     8881 cttagcagag aacggacgat acaaatgaac agaaaccaaa ccaacttttt caccctgagc
     8941 agtcaggtgg tcgatagctt cgcgggcagc ttcggttaca gaacccattg cgataatcac
     9001 gcgttctgca tcttctgctc cgtagtaatc gaacaaacca tatttacggc ctgtgagttt
     9061 ggagatttcg ttcatatatt cttctacgat agcaggaact gcttcatagt atttgtttga
     9121 agattctctg tgctggaaga agtgatccgg gttttcagcc ataccgcgag cttccggttt
     9181 ttccggattc aaagcacgtg cacggaattc agccaacgcc ttctggtcga tcagcggagc
     9241 caggtcatca ttttccagag cttcgatctt ctggatttcg tgagatgtac ggaaaccgtc
     9301 gaagaagttc acgaaaggaa cgcgagactt gatagtagcc aggtgagcta cacccgccaa
     9361 gtccataact tcctgaacag aaccttctgc caacattgcg aaaccagtct gacgagcaga
     9421 cataacatcc tgatgatcgc cgaagataca caaggcatga gatgccagtg tacgggcaga
     9481 tacatggaat acgcaaggaa gcaactcacc ggcaatcttg tacatattag ggatcatcag
     9541 caacaatccc tgagaagccg tgtaagttga agtcagggca ccagcctgca aagaaccgtg
     9601 aactgcacct gcagcaccac cttctgattg catttcctgt accataacag tttcgccgaa
     9661 aatgttctta cgtccggcgg cagcccattc gtctacatat tctgccattg tagacgacgg
     9721 agtgatgggg tagatagcgg ctacttcact gaacatatat gaaatatgag cagcagcctg
     9781 gttaccatca caggtcaaaa atttcttctg ttttgtcata gacttttact attagtattt
     9841 aaaagaattt cttagtataa aaagccaaac agccaaagcg ggatcatatt ctcttctcct
     9901 acttcgacct tgtctacagc atagtataaa tcgggattgt tttttacttt catactttcc
     9961 tctatcctga aattatactt tccgtttacc aaaaagtgtg cgttcttcat tccctcattt
    10021 agcgtattgt ctttcaaaag ctggttatag aaaaaagatt cgcgcacagc ctgcacattt
    10081 acctccatcg gacggatggg gtacatcaga ttcgaattgt acatatacac agtagatggt
    10141 tttttcggaa acgattcgcc taccggatat aacatattca ttaaacgggc atcggtcaga
    10201 tattttatat aattcatcac tgtagcccgt gacgtttcta tttctttgct caactgactg
    10261 acattcggcg tacacggtgc gctgatagcc agcagataca acagtttgcg gagtttgggc
    10321 agataacttt gctcgatttg cttgatgtac aagacatcta cctccagcat catattcatt
    10381 gtcttcaaca ggttctctga gaaattgcgt ttctccagga agaacggata aaaaccatga
    10441 tgcaaataat cctgaaaata agccatcggt ttggctaccg aacaaatatt cttcgcaatc
    10501 tcctgatggt tcccgattat ttcttcaaac gtataagccg gaaaactgtt tcccgacatc
    10561 agattcaaaa actctcggaa agaaaaacca cgcaaattat atgaaacaac tttacctgag
    10621 agatccggat tttcctcttt caacctcatc actgacgaac cggaaaagat aatcttcaga
    10681 tcttcaaaat tatcataaca ataacgtaac tctttcgacc atccggaata tttgaaaacc
    10741 tggtcaatca acaacacctt ccctcctttt gccctgaact cagaagcaaa gtcgaccagc
    10801 gtacgttccg taaaataaaa gtgattcaga tttatataca ggcactcttt attatcagca
    10861 ccaaaatgtt cgcgggcata atccagcaaa aaagtagttt tccctactcc acgagagcct
    10921 ttgatcccga tcaaccggtc attccaatca atctcatcca tcagcccccg gcgtaccggt
    10981 gcatgcaaat gttctacaag gtatttatgt gttttaaaga atgcttccac ctgactgtct
    11041 tactatatag accgcaaaga tagaaaatat cctcaacttt gcaataccga gatagcaatt
    11101 ttattttcag ttggcaatcc aaagttggca aagcgtattg acgtttgaga atttagagtt
    11161 ggcagttaat gcttccggtt tatctaaaaa cattaactgt caacatcttt tatctgatta
    11221 ttcaattacc gtaacccaac cgtatgtatc aggttcgtca ccgtattgga tgccacgcag
    11281 tttgttatat agtttttcgc aaacaggtcc gggtttaccg tccttggcta tcacgtatga
    11341 tttattttca tccaaatcat caatctgtga aatcggggcg ataacggcag ctgttccgca
    11401 ttctgctgct tcatcgaatg tagctatttc ttcaaaagga acaggacgac gttcaaccgt
    11461 cagtcccata tcttcagcca gctgctgcaa actcttgtta gtgatagacg gcagaataga
    11521 atgagactgc ggagtgatgt aactgtttcc acgaataccg aagaagttgg caggaccgca
    11581 ttcgtccaga tatttctttt ctttcgggtc cagatacaat acggcggcat accccttttc
    11641 atgcgctatt tctccggcta ccaggctggc tgcataatta ccaccgactt tgatcgtccc
    11701 agtcccataa ggcgcagcac ggtcgtattc acgcatgata caaacctttg acggtttgaa
    11761 accacctttg aaataaggtc ctaccggggt tacgaatacc ataaacatat attcgggagc
    11821 cggttttacg cccacctgcg cacccaaacc gatcatcagc gggcggatat ataatgctgc
    11881 tccactctca tagggaggaa caaaacgctc gttcaacttc acaactttac ggactgcttc
    11941 ttcaaacatt tccacaggaa gttcagccat cttgatgccc cggctggaag cttgcatacg
    12001 tttgccgttt tcatccatac ggaacacacg gattctaccg tcttttccct tgaatgcttt
    12061 caaaccttca aacgactcct gtccgtaatg gaggcaagta gctgccatgt gaatattgat
    12121 aatttcagaa gagctaactt ccaattcacc ccacttacca tcacgatagt aacaccgtac
    12181 attgtagtct gtcttcatat aaccgaatgc cagatcagac caattcatat tttccatatc
    12241 ttgtcgtaat tagattatga gcgcaaaagt aagctatttc ggatgataat tgttactttt
    12301 gcagcaaaaa taattaaaat atgaaagtta ttgatctgat caacggcagt aaaacgactg
    12361 ctttttcatt tgaaattcta cctcctctga aagggaacag catacagaag gtatataatg
    12421 tgattgataa actgaaagaa ttcgacccta aatacattaa tataacttct caccatagcg
    12481 aatatatcta taagaccttg cccgacggca gcttccagaa agtgaacatc cgcaagcgcc
    12541 cgggttcggt tgccattgct tctgccatcc agaacaaata tggtattccg gcagttccac
    12601 atattatatg taagggattt acaaaagatg aaacggaata tgcattgatc gatcttaatt
    12661 tcctgggagt ttacgacctg ctgctgttgc gtggtgatgt aaaaacactg gaagccggac
    12721 aaaatacgga tttatatcac gaacatgcga ctgaccttca ggaacaggta aacaatttca
    12781 ataaaggtat tgccgtagac ggttccacat tcgaagcaaa cgaaacaccg ttctcatacg
    12841 gtatggcttg ctatccggaa aaacatgagg aagcaccgaa tatggaatcg gatatttttt
    12901 atctgaaaga gaaagtaaaa aacggtgccg actatctggt tacccagatg tttttcgata
    12961 atgaaaaata ttattcattt gtggaacgct gccgtgccga aggtatcgat gtcccgatca
    13021 tcccaggcat caagccggtt gtctttaaaa accagctgac cgtattacct aaaatattcc
    13081 gctcagacat tcccgaaccg tttgcagccg aattgcgcaa atgcaaaaat gatgatgaag
    13141 taaaagcggt tggcgtggaa tggtgcatcc agcaatgcaa agacctgatc gcccacggtg
    13201 tccccagcct gcatttttat acaatgatgg ctacggatag tgtttataaa gtggcaaaag
    13261 aagtatatta aaatcgttga tggaactaat cgattgccag gagacaacgg attggataaa
    13321 aagcgtaata ctgactaaat ccggagaaca ttactatgtc ttataaatta gaggtaggtg
    13381 taaatgaatt tagacgtacc tctaattcga tttacaccta cctctaaatt tatttagacc
    13441 tacctctgtc tgaaaaaaca ttagattgct ttacgcagat caactgaata actttacacc
    13501 gtgaagcgat tcaaatcctt atcttcacaa ttatagaaac catcgatatg aatattattc
    13561 tgcgtatcga tctccacaac agcaaaactg ttgttatcgg gaaggtttcc ttctatcatc
    13621 cctttcattg tccagtagtg gatattatta cggaaactgt aatgtcccgc atgatgatgt
    13681 ccctggaata cagctagcac attcccattt tcttccaaca gaggaactat ttcgtccgca
    13741 ttacttacac aaagcgattt actgatatcg gagaagcggt ctaacaactg atggataaaa
    13801 atgatgaccg gtttgttatt tcctttcaat tcttttttca accagtctat ctggtcttta
    13861 ggaatatatg cctttgtcca gtcaaaatta cctttatcat acggtgtacc gtccaaattg
    13921 taattcgcat ccaggactat gaattttata ttatcaaagg caaatgaata ataagctttc
    13981 ttgtcggcat ccccctgatt ggaggtatgt tgcaggaaat cgtctttgga gatgctatcc
    14041 atatcatgat ttcccaggac atgataaacc ggtccccgga acgattgaaa gacgttttct
    14101 atttcatcca gataagtaat tgtctgttcc cgctgagaga cgttatcctg atccttcaga
    14161 tcgcccattt cgatcacaaa atccagattg gaagagttga agacctccat ggcctctttc
    14221 aacttatcca ttgtctgagg gaaataacgg gtcccataag gttcccgccg cgaataatgc
    14281 agatcggtaa caaccccaaa ccggacaggc cgttgtccac cacaggatac aaatgaagga
    14341 gaagctgcca ggaccaacac ccctccgcat gcctttttta aaaataagcg tctgttcatc
    14401 atattaaaaa tttcataggt tatagagtca tgccggtaac ctgccggatg tagcaggcta
    14461 tcagcattgg cttacaatat taataataaa aagtcaatat atctaccatc ccggatttag
    14521 gatgagttga gaacaaattt tcaatctccc gaaaaaagct tatttgttaa attaccccaa
    14581 tttcaaaccc agatgcatct ttttagagcc tttgctcatc ttcttttcat acaaatacaa
    14641 aaaaatctgt caggccgata ggggtttttg aaatatttct gtcttacagg tggaatttaa
    14701 aagaaaaaag aaatgaaata catactattc attactatgg atctggcagt atatcctttt
    14761 ctgctactaa tttatatagt aaaatgcatc tttgataaga tacaaccag
//
