LOCUS       c00078_gnlPro..        14157 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EALPJDNL_78.
ACCESSION   c00078_gnlPro..
VERSION     c00078_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:01:24
            Original ID  :: gnl|Prokka|EALPJDNL_78
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14157
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14157
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[202:6169]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      203..6169
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14157
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14157
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..121)
                     /locus_tag="ctg78_1"
                     /transl_table=11
                     /translation="MEKGLRNISTTSQLLTHLSPYLLMTRRTTTRIICNTLFII"
     CDS             203..2038
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_2"
                     /sec_met_domain="ILVD_EDD (E-value: 3.8e-217, bitscore:
                     711.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEVGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGTDFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             2072..3775
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-50, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVEYEYKKVDYVRSYQPEPDINKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVAVDVKVLGNAKHTIPMITALLEERR
                     RLEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             3791..4345
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.8e-17, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             4352..5077
                     /locus_tag="ctg78_5"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             5135..6169
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_6"
                     /sec_met_domain="IlvN (E-value: 2.4e-47, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.1e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQSLN
                     LRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMSVWP
                     TMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGRGLN
                     SSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGLLLA
                     QYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMGPFH
                     DAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVRKLR
                     PENN"
     CDS             complement(6247..6588)
                     /locus_tag="ctg78_7"
                     /transl_table=11
                     /translation="MDGQLSRKKVIGSPIYEESLERTFVEGIERFGMFQARKYLEHILN
                     TVEKLENDYPYYPECRHLTTKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KQARNIHIE"
     CDS             complement(6558..6791)
                     /locus_tag="ctg78_8"
                     /transl_table=11
                     /translation="MTKLSNNPTKETTAKTAKTRKTKTGPAKLKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFYPIEEVHQRIRSWMDSYQGKK"
     CDS             7093..7311
                     /locus_tag="ctg78_9"
                     /transl_table=11
                     /translation="MMGNVSSLYCPSLRPNDGQCYLVTDAIVYLTFYKKYTAKNFELYL
                     VVSKKAVSLQRSNKNNKDKNNDTQLAK"
     CDS             7474..8976
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_10"
                     /sec_met_domain="HMGL-like (E-value: 6.4e-95, bitscore:
                     307.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNTVEKIQVAKALEQLGVDVIEA
                     GFPVSSPGDFKSVVEISKAVTWPTICALTRAVEKDIDVAAEALKFAKRGRIHTGIGTSD
                     SHIKYKFNSTREEIIERAIAATKYAKKYVEDVEFYCEDAGRTDNEYLARVVEAVIKAGA
                     TVVNIPDTTGYCLPDEYGAKIKYLMEHVDGVHNAILSTHCHNDLGMATANTVQGVLNGA
                     RQVEVTVNGIGERAGNTSLEEVAMIFKSHKERDIITNITTNKIYSTSRMVSSLMNMPVQ
                     PNKAIVGRNAFAHSSGIHQDGVLKNAQTYEIIDPKDVGIDDNAIVLTARSGRAALKHRL
                     HVLGVDLEQEKLDKVYDEFLKLADRKKDINDDDVLMLVGKDRTATHRIKLEYLQVTSGV
                     GVQSVASICLNLSGVRKYEAAAGNGPVDAGIKAVKKAISNSDMTIQEFLIQAINKGSDD
                     TGKVHMQVEYNGATYYGFSANTDIIAASVEAFVDAINKFIVD"
     CDS             8991..10388
                     /locus_tag="ctg78_11"
                     /transl_table=11
                     /translation="MSKTLFEKIWDKHVVDTLPDGTIQLYIDRLYCHEVTSPQAFAGLR
                     ARGLKPFRPAQITCMPDHNIPTLNQDKPIEDPISKNQVDTLEENAKYFGLTYYGLQHPK
                     NGIIHVVGPETGLTQPGMTIVCGDSHTSTHGAMGAIAFGIGTSEVEMTLATQCIMQRKP
                     KTMRITIDGVRKPGVTAKDFALYIISKMSTSGATGYFVEYAGEAIRNTTMEERLTICNL
                     SIEMGARGGMIAPDDVTFDYLKDREFAPRGEEWERKVSEWRQLYSDPDAKFDKEIVFHA
                     EDIDPMVTYGTNPGMGMSISKDIPSLESVPEAGRISYKKSLDYMGFKAGESMLGKKVDY
                     VFLGSCTNGRIEDFRAFASLVKGKKKADDVTVWLVPGSWQVEREIRAEGIDKVLAEAGF
                     VLRQPGCSACLAMNEDKVPAGKYAVSTSNRNFEGRQGPGARTILAGPLVAAAVAVTGKI
                     TDPRELM"
     CDS             10415..11002
                     /locus_tag="ctg78_12"
                     /transl_table=11
                     /translation="MKTKFNIITSTCVPLPLENVDTDQIIPARFLKATTKEGFGENLFR
                     DWRYDKEGNKIESFVLNDPTYSGKILVAGKNFGSGSSREHAAWAIADYGFRVVVSSFFA
                     DIHKNNELNNFVLPVVVTEEFLAELFDSIYKDPKTEVEVNLPEQTITNKATGKSEHFEI
                     NAYKKDCLINGLDDIDYLLANKSKIEAFEAAR"
     CDS             11005..12519
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_13"
                     /sec_met_domain="HMGL-like (E-value: 2.5e-49, bitscore:
                     158.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEIMDTTLRDGEQTSGVSFAAHEKLSIAQVLLSDLGVNRVEIAS
                     ARVSDGEFEAVKRVAAWAARSGNLDKLEVLGFVDGTVSLDWIESAGCRVVNLLCKGSYK
                     HVTEQLRKTPEQHVDDIRTVVLEAAKRKIDVNIYLEDWSNGIKHSPDYVFLVIDALKGL
                     PICRFMLPDTLGVLNPGNTYEYCKMMVDRYPDLRFDFHAHNDYDLAVANVYSAIRAGIK
                     GIHTTVNGLGERAGNAPLSSVLAVIKDQLGEETSLREEKINKASRLVETYSGVHIPPNK
                     PIIGEHVFTQCAGVHADGDSKNNLYCNDLLPERFGRVREYALGKTSGKANIRKNLEALG
                     IDMDEGSMRKVTERIIELGDKKEMVTPEDLPYIISDVLHHDNALEDQKIRILNYSLSLA
                     QGLKPVATLKIEINGEAYEESASGDGQYDAFVRALRRIYSRLNRPFPMLTNYSVSIPPG
                     GRTDAFVQTVISWNYAGVDFKTRGLDADQTEAAIKATLKMLNKIED"
     CDS             12540..12983
                     /locus_tag="ctg78_14"
                     /transl_table=11
                     /translation="MKKLTIALVAHDNRKAEMVEWAVHNAEFLSHHHIVCTGTTGNLVR
                     KALEEKGVNADIACMHSGPMGGDAEIAAMVVRKEIDLAVFLIDDLNPQPHEADIQMLLR
                     QCRVHNVPIACNRYSADLMITSTLWDDDTYFPTEPKYVHFNRE"
     CDS             12999..14060
                     /locus_tag="ctg78_15"
                     /transl_table=11
                     /translation="MKLNIAVLPGDGIGPEISVQGVEVMSAVCEKFGHEVHYEYALCGA
                     DAIDKVGDPFPEETYRICKDADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGLFA
                     NIRPVQTFKCLLHKSPLRAELVDGADFLCIRELTGGMYFGEKYQDNDKAYDTNMYTRPE
                     IERILKVGFEYAMKRNKHLTVVDKANVLASSRLWRQIAQEMAPSYPEVTTDYMYVDNAA
                     MRMIQEPKFFDVMVTENTFGDILTDEGSCISGSMGLLPSASTGESTPVFEPIHGSWPQA
                     KGLNIANPLAQILSVAMLFEYFDLKEEGALIREAVDASLDANVRTPEIQVEGGAKYGTK
                     EVGSWIVNYITEK"
ORIGIN
        1 agatgatgaa caacgtattg catattattc tcgtggtggt ccttctagtc attagtaggt
       61 aaggagaaag gtgtgtaaga agttgtgaag tcgtagagat atttcttaag cctttctcca
      121 tatagggaaa ggctttttta ttataaataa atcaaggtag aggcgtggat aaagcgctct
      181 acgaacaaaa aataggaaag agatgaagaa tccgttaaga agctcattta gcaccgaagg
      241 tcgtaggatg gccggagccc gtgcgctatg gcgtgccaac gggatgaaag aggaacagtt
      301 cggcaagcct attatcgcta tcgtaaattc atttacccag ttcgtgccgg ggcatacgca
      361 tttgcatgag gtcgggcaat tggtcaaggc cgagatcgag aaacaaggtt gtttcgccgc
      421 tgaatttaat acgatcgcta tcgacgacgg tatcgctatg gggcacgatg ggatgcttta
      481 ctcgcttcct tcacgcgaca ttatcgcgga cagcgtggaa tatatggtaa atgcccataa
      541 ggcggacgct atggtttgca tcagcaattg cgataagatc acgccgggta tgcttatggc
      601 ttccatgcga ttaaatatcc cgacggtgtt cgtgtccggt ggcccgatgg aggcaggtga
      661 gctggatggc cgccatcttg atttgatcga cgcgatgatt gagtctgccg atacatcggt
      721 aagcgatgag cgtatcgagc aggtggaacg ccatgcgtgt ccgggttgcg gttgttgttc
      781 cggtatgttt accgctaact ctatgaactg cttgaacgag gcgatcggtc tggcgcttcc
      841 gggtaacggg acgatcgtgg ctacccataa gaaccgtatt caacttttcc gtgacgcggc
      901 taagcaaatc gttgagaacg cttacaaata ctatcgtgac ggggatgatt ccgtgttacc
      961 tcgcaacatc gctacccgtc aggctttctt gaacgccatg tcgctggata tcgccatggg
     1021 ggggtctacc aatacggtgc ttcacttatt ggccgtggca caagaagccg gcaccgattt
     1081 tcatatggag gatatcgata tgttatcccg caagactcct tgcctgtgta aggtagcccc
     1141 gaatacgcac acttatcatg tacaagacgt aaaccgtgcc ggtggaatcc tcggtatcat
     1201 gaacgagttg atgaaagccg ggcttgtgga tggcagcacg agacgtgcgg acggcctgac
     1261 cttggccgag gctgttgata aatacgccgt cacttccccg aacgtaacgg aggaggcgat
     1321 ccgtaaatac aagagcgctc ccgctcatcg gttcagtatc cagatgggtt cccaagaatc
     1381 ttattataag gaattagata cggatcgtgc cgaaggttgt atccgcgacg tggagcacgc
     1441 ttattccaag gatggcggct tggctgtttt gagagggaat atcgccttgg acggatgtgt
     1501 cgtaaaaacc gccggtgtgg atgagagtat ttggaaattc tccggcccgg cgaaagtctt
     1561 cgattcacag gatgccgctt gcgagggcat tttaggaggc aaggtcgttt caggcgatgt
     1621 ggtcgtcatc acgtatgagg gtccgaaagg ggggccggga atgcaagaga tgttatatcc
     1681 tacttcttat ataaagagcc gtcacttagg taaggagtgc gccttgatca cggatggtcg
     1741 tttcagtggc ggtacgtccg gcctttctat cgggcatatc tctcccgagg ccgcttccgg
     1801 tggcgctatc ggactggtga gagacgggga tatcatcgag atcaatatcc cggaacgttc
     1861 catcaacgtg cggttgagcg acgaggagtt ggccgagcgc cgtaaagcgg aagaggcacg
     1921 tggaaagaaa gcctttacgc cgccgacgcg tcagcgtgag gtctcgaaag cgttgagagc
     1981 gtacgggaag atggttagct ccgccgataa gggaggtgta aggattgttg aagattaaag
     2041 ccaataatat acattaaaca cgttatttct tatggagaaa caaaagataa ccggttcgga
     2101 agctttgctg aaagcgttga ttgctgaagg agtagatact atcttcggtt atcccggagg
     2161 acaggcgata cctatttacg acagtttata tgattatagg gaccagttga ggcatgtatt
     2221 ggtgcgccac gagcaaggcg ctacccatgc ggctcaagga tatgcccgtg tatccggcaa
     2281 ggtaggagtg acgttggtta cttccggccc gggcgctacg aataccatca cgggtatcgc
     2341 tgatgcgctg atggatagta cgccaatggt cgtaatcgcc ggtcaagtac cctcgccgtt
     2401 gttgggaacc gatgcttttc aggaagtcga cgtgattggc atcacgcaac cgatcacgaa
     2461 atgggcttat caaatccgta agccggagga gatcgcatgg gctgtttctc gtgcttttta
     2521 tatcgcttct acaggccgtc cgggtccagt tgtgctggat ttagcgaagg acgcgcaagt
     2581 agggttggtg gaatatgaat ataagaaggt cgattacgta cgtagttatc aaccggagcc
     2641 ggatatcaat aaggatcgta tcaaggccgc cgccgattta atcaatgagg cgaagaaacc
     2701 cttctgtctg gtcggacagg gagtattgtt aggcggtgcg gaagaggaat tgaaagcgtt
     2761 tctccaaaag aatgatatac ctgccggatc tacggtattg ggcttatctg cgttgccaac
     2821 cgatttccca ttgaacaagg gaatgctcgg catgcatgga aacgtagggc cgaaccggaa
     2881 aacgaatgag tgtgatgtat tgatcgctat cggtatgcgt ttcgacgacc gtgtgactgg
     2941 cgatttaaag acatacgcta agcaagccaa gattatccat ctggatatcg ataactcgga
     3001 aataggcaag aatgttgccg tggatgtaaa ggtgctgggt aatgccaagc acacgatacc
     3061 gatgatcacg gcgttgttgg aagaacgtag acgtctggaa tggaatgccg agttcgatcg
     3121 ggacgagaaa gaggaatacg ataaggtaat cgagaaggaa ttgtatccga ccgagggcca
     3181 actgaaaatg ggcgaggtag tccgtaaggt ttccgaggcg accggtaacg acgctgtatt
     3241 ggtaaccgac gttgggcaga accagatgat gggcgtccgc tatttcaaat ataaacaaac
     3301 ccgtagcgtg gtgacttccg gtggtttagg tacgatggga tttggtctgc cggccgctat
     3361 gggcgctaag ttcggagctc cggaccgtac ggtctgcttc tttaccggtg atgggggtat
     3421 gcagatgacg attcaggaat tgggcactat catgcaggag aaactgaacg tgaagattat
     3481 cattcttaat aataacttct taggtatggt acgtcagtgg caagaattgt tcttccacga
     3541 gcgttattca aacaccatca tggagaatcc ggatttcgtg gcgatcgcta aagcctatgg
     3601 tatcgccggc cgtgccgttg aaaagcggga ggaattggac gacgctatcg ctgagatgct
     3661 aaaccacgac ggcgcttacg tgttggtcgc taacgtggag acttgcggaa tggtatatcc
     3721 gatggttcct gccgggggaa gcgtgacaaa catgattatg ggagacgaga aataaggagg
     3781 agatgaagct atgacaacaa agaaattata taccgttatt atcttttcag agaatatcgt
     3841 aggtcttttg aaccagataa cgattatctt tacacgccga cagctgaaca tcgagactct
     3901 gtccgtctct ccgtccgcta tcaagggtat ccataagttt acgatcacga cattcgccga
     3961 tgaggatatg atcgataagg tggtgaaaca gatcgataaa cgtgtggata tcttgaaggc
     4021 ttattataat acggatgagg atttggttta tcaagagatc gctctttata agctaagtac
     4081 cgagcttttc atcaagatgg gaaccgtgga gggattgatc cgtaaataca acgctcgtat
     4141 cttggagatg aacgagacct gcgtggtatt ggagaagagt ggccactatg acgagacaca
     4201 agccttgttc aatgagttga gcgagacgat cggtgtcctg caattcatcc gctccggacg
     4261 tgtggctatc acgaagagca aggtggagcg cttgagcgat atgttggccg atatggagcg
     4321 aaagttacat gaaaagcaac aataataaga tatggagaaa gtaggattat ttcatttcgt
     4381 ggcggagccg tatttgatgg atttcagggg acgtgtaacg ctccctatga ttggtaacta
     4441 tttgattcac gccgcttcca gccatgccgg agagcgtggg ttcggtttca atgatatgtc
     4501 ggagcgtcat acggcttggg tgttgtcccg tctggctatc gagatgaagg aatatcctac
     4561 cgccttcgat aagattaatc tatacacttg gatcgatgag gtcggacgcc tcttcaccag
     4621 tcgttgtttc gagctggcgg atgagaatgg gaaaaccttt ggattcgccc gttctatttg
     4681 ggcggctatc gacgtggaga cccgccgtcc taccttattg gatatagagg cattgggcaa
     4741 atatatcgac gagcgtccgt gcccgatcga gaagccgggc aagatcatgc cggcggagaa
     4801 taaggcggag ggaatcccgt attcgatcaa atacagcgac ttggatatca acggtcactt
     4861 caatagcgtg aagtatatcg agcatctgct ggatttgttc gatatcgacc agttcaagac
     4921 ccgtgagatc ggccgtctgg agatcgccta ccaatccgag ggtaaacaag gtatgccgct
     4981 tacgcttcat aaggcggagt ccgctcccga taagcaagac atggctattt gccatgaggg
     5041 aaaggcgatc tgtcgtgcgg cggttacttg gagataataa gagagataca taaataggtt
     5101 tttaaacatt aatagttaaa aaaaaatggc acaaatgaat tttggcggtg ttgtagagaa
     5161 tgtaatgacc cgcgaggaat ttccgttgga aaaggcaaga gagatattaa aagatgagac
     5221 aatcgctgtt atcggctatg gcgtacaggg accgggacag tcattgaacc ttcgtgacaa
     5281 tggcttcaac gtaatcgttg gccagcgcca aggtaagact tacgataaag cggttgagga
     5341 cggatgggtt ccgggtgaga ctctgttcgg tatcgaggag gcttgcgaca aggccacgat
     5401 catcatgtgc ttgttgtccg acgctgccgt aatgtctgta tggcctacga tgaagcctta
     5461 tttgacagct ggcaaggccc tgtatttctc tcatggtttc gcgatcactt ggaacgatcg
     5521 tacgggcgtt gttcctcccg cggatattga cgtgatcatg gtcgctccga aggggtctgg
     5581 tacgtctttg cgttccatgt tccttgaggg tcgtggcttg aactcttctt tcgctatcta
     5641 tcaagacgct actggcaagg cgatggatcg tacgttggcg ttgggtatcg gtatcggttc
     5701 cggctacttg ttcgagacga ctttcatccg tgaggctact tccgatttga ctggtgagcg
     5761 tggttccttg atgggcgcta tccaaggttt gttgttggcc cagtatgagg tattgcgcga
     5821 gaatggacat actccttccg aggctttcaa cgagacggtc gaggagttga ctcaatcctt
     5881 gatgcctttg ttcgccaaga atggtatgga ctggatgtac gctaactgct ctacgactgc
     5941 ccagcgtggc gctttggact ggatgggtcc gttccacgac gcaatcaagc cggttgtcga
     6001 gaaattgtac gcgaacgtaa aatgcggtaa cgaggctcag atctctatcg actcaaactc
     6061 taagccggat tatcgtgaga aattggaggc tgaattgaag gcattgcgcg agagcgagat
     6121 gtggcagaca gctgttactg tacgcaagct tcgtccggag aacaactaat ccaatcttaa
     6181 tccttatata tcagcaaaaa gaggcgggtc acttacgggt ggctcgcctt tttctgtttc
     6241 tctgcatcat tcgatgtgga tattcctagc ctgtttgatc tttcgcatgc tggatgcgga
     6301 atggacgatg tctagcactt cgatacgctc ctcggtgatg cggtagatga taaggtgtga
     6361 atctaggatg atgttccggt acatgcggct tttcgtggtt aggtgtcggc attcggggta
     6421 ataaggatag tcgttttcta gtttctcgac tgtattcaat atatgctcaa gatatttccg
     6481 ggcttggaac ataccgaatc gttctatgcc ttccacaaaa gtcctctcaa ggctttcctc
     6541 gtaaatggga gaaccgatta cttttttcct tgatagctgt ccatccatga tcttattctt
     6601 tgatgtactt cttcaatagg atagaacggt cccttctcaa tctcatggat atgttcccag
     6661 atctcttctt gggtgaattg caccggcttg gtgggatccc acttgagctt tgcgggtccg
     6721 gtcttggtct tacgtgtctt tgcagtcttg gccgtagttt ccttggtggg gttgttgctt
     6781 aattttgtca tagtcgtaac tgttatttat tagtacagtg gcaaatgtat ggaataattt
     6841 ccatgtaata agatatttgg taaggaaaaa agtaggtcta taggattaac ttattaccca
     6901 gttgtagaga cggggcgtgc cccgtctcat ctcctcaata gggtagagaa gcttaccttg
     6961 cctaagaata aaacagtatt gcgttccttg atgttatccg gtaatacgct gctcttgttc
     7021 gtgaagaaga tcgtagctcg ttaaaatgag ctgtctcaca tatttcataa cactgcccat
     7081 cataaggcct ttatgatggg caacgtaagc agcttatact gcccatcgtt acgacctaac
     7141 gatgggcagt gttatttagt aacagatgca attgtttatc ttacgtttta taagaaatat
     7201 actgcaaaaa acttcgaatt atatttggtg gtatcaaaaa aggccgtatc tttgcaacgt
     7261 tcaaacaaaa acaataaaga caagaacaat gacacgcaac ttgcaaaata gtctcattat
     7321 ttctctaaac attattctac tctgggaacg ggataggaag tgagactgta tgctttgcga
     7381 gcattacgat agatgaaaga gcctttctca cttccttgtg agagaggctt ttttagttag
     7441 tataggatat tagtaaatta agaatataag attatgtcag acagattatt tattttcgac
     7501 accaccttac gtgatggtga acaggttccg ggatgccagt tgaatacagt ggaaaagatt
     7561 caagtagcta aggcattgga acagctaggt gttgatgtga tcgaggctgg tttccctgtc
     7621 tccagtcccg gggattttaa gagtgtggtt gagatctcaa aggccgtgac ttggccgacc
     7681 atctgtgcct tgacccgtgc ggtggagaaa gatatcgacg tggcagccga ggcgttgaaa
     7741 ttcgctaagc gaggacgtat tcatacgggt atcggtactt ctgattctca tatcaaatac
     7801 aagtttaact ccacgagaga ggagattata gagcgtgcga tcgccgccac gaaatacgct
     7861 aaaaagtatg tggaggacgt agaattctac tgtgaggatg ccgggcgtac ggataatgaa
     7921 tatctggccc gtgtcgtgga ggccgtgatc aaggccgggg ctaccgtagt gaatatcccg
     7981 gatacgacag gatattgctt gccggatgag tacggggcga agattaagta tctgatggaa
     8041 catgtggatg gcgtacataa cgctattctt tccactcatt gccataatga cttgggcatg
     8101 gctactgcga ataccgtaca aggcgtgttg aacggagccc gtcaggtgga ggtaaccgta
     8161 aacggtatcg gtgagcgtgc gggtaacacg tcattggaag aagtcgccat gattttcaag
     8221 agccataaag aacgtgatat catcaccaat atcacgacga ataagatcta tagtacgagc
     8281 cgtatggttt ctagcttgat gaatatgccg gtacaaccga ataaggctat tgtcggacgt
     8341 aacgcattcg ctcactcctc cggtatccat caagatggcg ttttgaagaa tgcgcaaacc
     8401 tacgagatca tcgatccgaa ggatgtgggt atcgatgata acgcgatcgt attgactgct
     8461 cgtagcggtc gtgcggcgtt gaagcatcgc ttgcatgttt taggtgtgga tctggagcag
     8521 gagaaattgg acaaggtgta tgatgagttc ttgaaactgg ccgatcgtaa gaaagatatt
     8581 aatgatgatg atgttttgat gttggtcgga aaggatcgta cggccaccca ccgtattaaa
     8641 ttggaatatt tacaggtaac tagtggtgtt ggagtacaat cagtcgcaag tatttgttta
     8701 aatttgtcgg gagtaagaaa atacgaggcc gcggctggta acggtccggt tgacgcaggc
     8761 atcaaggcgg tgaaaaaagc gattagtaat agtgacatga cgattcagga attcttgatt
     8821 caagccatta ataaaggtag cgatgatacg ggcaaggtgc atatgcaggt agagtataac
     8881 ggggctacct attatgggtt ttctgcgaat accgatatta tcgctgcttc cgtggaggct
     8941 ttcgtggacg ccatcaataa gtttatagta gactaaaaat agacaagaca atgagcaaga
     9001 cattatttga gaaaatctgg gacaaacacg tggtggacac gttgcccgac ggaaccatac
     9061 aattgtatat cgaccgtctg tattgtcatg aggtgactag cccgcaggct ttcgccggat
     9121 tacgtgcacg tggattgaag cccttccgtc ccgcgcaaat cacttgtatg ccggaccaca
     9181 atatcccgac attgaaccaa gataagccta tcgaggaccc tatatccaag aatcaagtgg
     9241 ataccttgga agagaacgcg aagtatttcg gcttgacgta ttacggtctt caacatccga
     9301 agaatggtat catccatgtg gtaggtccgg agacaggctt gacgcagccg ggtatgacga
     9361 tcgtttgtgg cgactcccat acttctacgc acggtgccat gggcgctatc gccttcggta
     9421 tcggtacgag cgaggtggag atgaccttgg ctacccaatg tatcatgcag cgtaagccga
     9481 aaacgatgcg tatcacgatc gatggtgtac gcaaaccggg cgttacggcg aaggactttg
     9541 ctttatacat tattagtaag atgagtacca gcggtgctac gggctatttc gtagagtacg
     9601 ctggcgaggc gattcgtaat acgaccatgg aggaacgttt gacaatctgt aacctttcga
     9661 tcgagatggg tgcccgtggc ggtatgatcg ctccggatga tgttactttc gattatttga
     9721 aagaccgtga gtttgcccca agaggcgagg aatgggagcg gaaggtgagc gagtggcgtc
     9781 agctatatag tgatccggac gctaagttcg ataaggagat cgttttccac gccgaggata
     9841 tcgacccgat ggttacgtac ggtacgaacc cgggcatggg tatgagtatc agcaaagata
     9901 tcccctcctt agaaagcgtg cccgaggcag gccgtatctc ttataagaag tctttggatt
     9961 atatgggctt caaggcaggc gagtctatgt tgggtaagaa agtggattat gtctttttag
    10021 gtagctgtac gaatggccgt atcgaggatt tccgtgcttt cgcctctttg gtgaaaggaa
    10081 agaagaaagc ggatgatgta acggtttggc tggttcccgg cagttggcag gtagagcggg
    10141 agattcgtgc cgaggggatc gacaaggttt tggccgaggc cggcttcgtc cttcgtcaac
    10201 cgggatgttc cgcttgtctg gcgatgaatg aggataaggt tccggcgggt aaatatgcgg
    10261 tctccacttc caaccgtaat ttcgaggggc gccaaggacc gggtgctcgc accatcttgg
    10321 cggggccgct tgtggccgcc gccgtcgctg tgacaggtaa gatcacggac ccgagagaac
    10381 tgatgtaaag actaatctaa taaagtagca taagatgaaa acaaaattca atataatcac
    10441 aagcacttgc gtgcctcttc ctttagagaa cgtggatacc gaccagatta ttccagcccg
    10501 ctttctgaaa gcgactacca aggaagggtt cggcgagaac ttattccggg attggcgata
    10561 tgataaggaa ggtaataaga tcgaatcatt cgtcttgaac gatcctacgt atagcggaaa
    10621 gatattggta gcgggaaaga acttcggttc cggttccagc cgtgagcatg cggcttgggc
    10681 gatcgccgat tacggtttcc gtgtcgtggt ctccagtttc ttcgccgata tccataaaaa
    10741 caacgagttg aacaacttcg tgctgccggt tgttgtgact gaagagttcc tcgctgaatt
    10801 gttcgattcg atttacaagg acccgaaaac tgaggtcgag gtaaatctac cggagcaaac
    10861 gatcacgaac aaggctacgg gcaaaagcga gcatttcgag atcaacgcct ataaaaagga
    10921 ttgcctgatc aacggattgg acgatatcga ctatttactg gcaaataaat caaagataga
    10981 agccttcgag gcagcacgct gattatgata gaaataatgg atacaaccct cagagatggg
    11041 gagcaaactt cgggcgtctc cttcgccgct cacgagaagc tcagcatagc gcaagtgctg
    11101 ctgagcgact taggcgtgaa ccgggtggag atcgcctccg cccgtgtgtc ggacggagag
    11161 tttgaggccg tgaagcgtgt agccgcttgg gccgcccgtt ccggaaacct agacaaattg
    11221 gaggtcttgg gtttcgtgga tggtacggtc tctctcgact ggattgaatc cgcaggttgc
    11281 cgtgtcgtga acttgctttg caagggttct tataagcatg tcaccgaaca gcttcgaaag
    11341 actcccgagc aacacgttga cgatattcgt acggtcgtat tggaagcggc gaaacggaag
    11401 atcgacgtga atatctattt ggaggactgg tcgaacggta tcaagcattc cccggattac
    11461 gtattcttgg taatcgatgc gttgaaagga cttccgatct gccgtttcat gctcccggat
    11521 accttgggag tcttgaatcc cggaaatacc tacgagtatt gcaagatgat ggtggaccgt
    11581 taccctgatt tacggtttga cttccatgcg cataacgact atgatcttgc cgtggcgaat
    11641 gtatattccg ccatccgtgc gggtatcaag ggaatccata cgaccgtgaa cggtttggga
    11701 gagcgtgcgg gtaacgctcc tttgagtagc gtacttgccg ttatcaagga ccagttggga
    11761 gaggagacga gcttgaggga ggaaaagata aacaaggcta gccgtttggt tgagacctac
    11821 tccggggtgc atatcccgcc caataagccg atcatcggag agcatgtgtt tacgcagtgc
    11881 gccggtgttc acgcagacgg tgatagcaag aataacttgt attgcaacga cttgcttcct
    11941 gaacgtttcg gacgggttcg cgagtacgcc ttgggcaaga cctccggaaa agcgaatatc
    12001 cgcaagaatc tggaagcgct cggtatcgac atggatgagg gctcgatgcg taaggttacg
    12061 gaacggatca ttgagttagg ggataagaaa gaaatggtta ccccggagga tcttccttat
    12121 attatcagcg atgtgcttca tcatgataat gcgctggagg atcagaaaat ccggatcttg
    12181 aactattcct tatccttggc ccaagggttg aaaccggtgg ctaccttgaa gatcgagatc
    12241 aatggcgagg cttacgagga atcggcttcc ggtgatggac aatacgacgc tttcgttcgt
    12301 gccttacgcc ggatttattc ccgtttgaac cgcccgttcc cgatgttgac gaactattcg
    12361 gtatccatcc cgccgggagg acgtacggat gcgttcgtgc agacggttat cagctggaat
    12421 tatgccgggg tcgatttcaa gactcgtggt ctggacgctg atcagaccga ggcggcgatc
    12481 aaggcgacat tgaagatgct gaacaagata gaggattaat aattaaaaag gtaaagggta
    12541 tgaaaaagtt gactatcgcg cttgtagcgc acgacaatcg taaggcggaa atggtagaat
    12601 gggcggtaca taacgctgag ttcttgtctc accaccatat tgtttgtacg ggtacgaccg
    12661 gaaatttggt tcgtaaagct ctcgaggaaa aaggggtgaa tgcggatatt gcttgcatgc
    12721 attccggtcc gatgggaggc gatgctgaga ttgccgctat ggttgtccgt aaggagatcg
    12781 atttggcggt ctttttgata gacgacttga atccgcaacc gcacgaggcc gacatccaga
    12841 tgttgcttcg ccagtgccgt gttcataacg tacctatcgc ttgtaaccgt tatagcgccg
    12901 acttgatgat tacaagtacc ctgtgggatg atgacacgta tttccccacg gagcctaagt
    12961 atgtacattt taacagagaa taataacaaa catttacgat gaaactgaat atagcagtac
    13021 ttcccggaga cgggatcgga ccagagattt ccgtgcaagg cgtggaagta atgagtgccg
    13081 tttgtgagaa atttggacat gaggttcact atgagtatgc cctttgtggc gctgacgcga
    13141 tcgataaggt aggcgatcct ttcccggagg agacctatcg gatttgtaag gatgccgacg
    13201 ctgttctttt ctcggccgta ggtgatccta agtttgataa tgatccgaca gcgaaagtac
    13261 gcccggagca aggtcttttg gcgatgcgta agaagttggg cctgttcgct aatattcgtc
    13321 cggtgcagac cttcaaatgc ttattgcata aatcgccgtt gcgtgccgaa ttggtggatg
    13381 gcgcggattt cttatgtatc cgtgagttga ccggtggtat gtatttcggt gagaaatatc
    13441 aagacaacga taaggcatac gatacgaata tgtatacccg cccggaaatt gagcgtatct
    13501 tgaaagtggg cttcgagtat gcgatgaaac ggaataagca cctgacggtt gttgacaagg
    13561 cgaacgtact tgcctcttcc cgtctatggc gccagatcgc tcaagagatg gctcctagct
    13621 atccggaagt aacgacagac tatatgtatg tggacaatgc cgctatgcgt atgatccaag
    13681 agccgaaatt cttcgacgtg atggtaaccg agaatacgtt tggtgatatc ttgacggacg
    13741 agggttcttg catcagcggc tctatgggct tgctgccttc cgcttctacc ggagagagca
    13801 caccggtttt cgagccgatc catggctctt ggccgcaggc gaaagggctg aatatagcga
    13861 accccttggc gcaaattctt tcagtagcga tgttattcga gtatttcgac ctcaaagaag
    13921 agggagcctt gatccgtgag gccgtagacg cttctcttga tgcgaatgtt cgtacgccgg
    13981 aaatccaagt ggaaggtgga gcgaaatatg gaacgaaaga agtgggtagt tggattgtca
    14041 attatatcac ggaaaagtag tataaatagg ccgatttcgc accagtagtg gcgcaggctc
    14101 acacgtatag tggcatcggc tcacgcgagt agtggcattg gcctacgtca ctactcg
//
