LOCUS       c00049_gnlPro..         8483 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAPGJCNG_49.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:17:07
            Original ID  :: gnl|Prokka|PAPGJCNG_49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8483
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8483
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:6156]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..6156
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8483
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8483
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..118)
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="MEKGLRNISTTSQLLTHLSPYLLMTRRTTTRIICNTLFI"
     CDS             200..2035
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_2"
                     /sec_met_domain="ILVD_EDD (E-value: 3e-217, bitscore:
                     711.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEVGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             2069..3772
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVEYEYKKVDYVRSYQPEPDINKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVAVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKLGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             3788..4342
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-17, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             4349..4558
                     /locus_tag="ctg49_5"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYR"
     CDS             complement(4701..4976)
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MKRKRHTLFTLGLVGDLQTADLTGLELVDIEQIQQVLDILHAIEV
                     TVDIQVAVFDRIRDSLRLILRRHDLARLLDRARTLVDIFAQCLYIQ"
     CDS             5113..6156
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_7"
                     /sec_met_domain="IlvN (E-value: 1.3e-47, bitscore: 150.9,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.1e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(6226..6567)
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MDGQLSRKKVIGSPIYEESLERTFVEGIERFGMFQARKYLEHILN
                     TVEKLENDYPYYPECRHLTTKSRMYRNIILDSHLIIYRITEERIEVLDIFHSASSMRKI
                     KKTKNIHIE"
     CDS             complement(6537..6770)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTAKTRKAKTEPAKPKWDPTKPMQFTQEEIR
                     EHIHEIEKGPFYPIEEVHQRIRSWMDSYQGKK"
     CDS             7453..8481
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_10"
                     /sec_met_domain="HMGL-like (E-value: 1.3e-95, bitscore:
                     309.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNTVEKIQVAKALEQLGVDVIEA
                     GFPVSSPGDFKSVVEISKAVTWPTICALTRAVEKDIDVAAEALKFAKRGRIHTGIGTSD
                     SHIKYKFNSTREEIIERAIAATKYAKKYVEDVEFYCEDAGRTDNEYLARVVEAVIKAGA
                     TVVNIPDTTGYCLPDEYGAKIKYLMEHVDGVHNAILSTHCHNDLGMATANTVQGVLNGA
                     RQVEVTVNGIGERAGNTSLEEVAMVFKSHKERDIITNITTNKIYSTSRMVSSLMNMPVQ
                     PNKAIVGRNAFAHSSGIHQDGVLKNAQTYEIIDPKDVGIDDNAIVLTARSGRAALKHRL
                     HVL"
ORIGIN
        1 tgatgaacaa cgtattgcat attattctcg tggtggtcct tctagtcatt agtaggtaag
       61 gagaaaggtg tgtaagaagt tgtgaagtcg tagagatatt tcttaagcct ttctccatat
      121 agggaaaggc ttttttatta taaataaatc aaggtagagg cgtggataaa gcgctctacg
      181 aacaaaaaat aggaaagaga tgaagaatcc gttaagaagc tcatttagca ccgaaggtcg
      241 taggatggcc ggagcccgtg cgctatggcg tgccaacggg atgaaagagg aacagttcgg
      301 caagcctatt atcgctatcg taaattcatt tacccagttc gtgccggggc atacgcattt
      361 gcatgaggtc gggcaattgg tcaaggccga gatcgagaaa caaggttgtt tcgccgctga
      421 atttaatacg atcgctatcg acgacggtat cgctatgggg cacgatggga tgctttactc
      481 gcttccttca cgcgacatta tcgcggacag cgtggaatat atggtaaatg cccataaggc
      541 ggacgctatg gtttgcatca gcaattgcga taagatcacg ccgggtatgc ttatggcttc
      601 catgcgatta aatatcccga cggtgttcgt gtccggtggc ccgatggagg caggtgagct
      661 ggatggccgc catcttgatt tgatcgacgc gatgattgag tctgccgata catcggtaag
      721 cgatgagcgt atcgagcagg tggaacgcca tgcgtgtccg ggttgcggtt gttgttccgg
      781 tatgtttacc gctaactcta tgaactgctt gaacgaggcg atcggtctgg cgcttccggg
      841 taacgggacg atcgtggcta cccataagaa ccgtatccaa cttttccgtg atgcggctaa
      901 gcaaatcgtt gagaacgctt acaaatacta tcgtgacggg gatgattccg tgttacctcg
      961 caacatcgct acccgtcagg ctttcttgaa cgccatgtcg ctggatatcg ccatgggggg
     1021 gtctaccaat acagtgcttc acttattggc cgtggcacaa gaagccggcg ccgattttca
     1081 tatggaggat atcgatatgt tatcccgcaa gactccttgc ctgtgtaagg tagccccgaa
     1141 tacgcacact tatcatgtac aagacgtaaa ccgtgccggt ggaatcctcg gtatcatgaa
     1201 cgagttgatg aaagccgggc ttgtggatgg cagcacgaga cgtgcggacg gcctgacctt
     1261 ggccgaggct gttgataaat acgccgtcac ttccccgaac gtaacggagg aggcgatccg
     1321 taaatacaag agcgctcccg ctcatcggtt cagtatccag atgggttccc aagaatctta
     1381 ttataaggaa ttagatacgg atcgtgccga aggttgtatc cgcgatgtgg agcacgctta
     1441 ttccaaggat ggcggcttgg ctgttttgag agggaatatc gccttggacg gatgtgtcgt
     1501 aaaaaccgcc ggtgtggatg agagtatttg gaaattctcc ggcccggcga aagtcttcga
     1561 ttcacaggat gccgcttgcg agggcatttt aggaggcaag gtcgtttcag gcgatgtggt
     1621 cgtcatcacg tatgagggtc cgaaaggggg gccgggaatg caagagatgt tatatcctac
     1681 ctcttatata aagagccgtc acttaggtaa ggagtgcgcc ttgatcacgg atggtcgttt
     1741 cagtggcggt acgtccggtc tttctatcgg gcatatctct cctgaggctg cttccggtgg
     1801 cgctatcgga ttggtgagag acggggatat catcgagatc aatatcccgg aacgttccat
     1861 caacgtgcgg ctgagcgacg aggagttggc cgagcgccgt aaagcggaag aggcacgtgg
     1921 aaagaaagcc tttacgccgc cgacgcgtca gcgtgaggtc tcgaaagcgt tgagagcgta
     1981 cgggaagatg gttagctccg ccgataaggg aggtgtaagg attgttgaag attaaagcca
     2041 ataatataca ttaaacacgt tatttcttat ggagaaacaa aagataaccg gttcggaagc
     2101 tttgctgaaa gcgttgattg ctgaaggagt agatactatc ttcggttatc ccggcggaca
     2161 ggcgatacct atttacgaca gtttatatga ttatagggac cagttgaggc atgtattggt
     2221 gcgccacgag caaggcgcta cccatgcggc tcaaggatat gcccgtgtat ccggcaaggt
     2281 aggagtgacg ttggttactt ccggcccggg cgctacgaat accatcacgg gtatcgctga
     2341 tgcgctgatg gatagtacgc caatggtcgt aatcgccggt caagtaccct cgccgttgtt
     2401 gggaaccgat gcttttcagg aagtcgacgt gattggcatc acgcaaccga tcacgaaatg
     2461 ggcttatcaa atccgcaagc cggaggagat cgcatgggct gtttctcgtg ctttttatat
     2521 cgcttctaca ggccgtccgg gtccagttgt gctggattta gcgaaggatg cgcaagtagg
     2581 gttggtggaa tatgaatata agaaggtcga ttacgtacgt agttatcaac cggagccgga
     2641 tatcaataag gatcgtatca aggccgccgc cgatttaatc aatgaggcga agaaaccctt
     2701 ctgtctggtc gggcagggag tattgttagg cggtgcggaa gaggaattga aagcgtttct
     2761 ccaaaagaat gatatacctg ccggatctac ggtattgggc ttatctgcgt tgccaaccga
     2821 tttcccattg aacaagggaa tgctcggcat gcatggaaac gtagggccga accggaaaac
     2881 gaatgagtgt gatgtattga tcgctatcgg tatgcgtttc gacgaccgtg tgactggcga
     2941 tttaaagaca tacgctaagc aagccaagat tatccatctg gatatcgaca actcggaaat
     3001 cggcaagaat gttgccgtgg acgtaaaggt gctggggaat gccaagcaca cgataccgat
     3061 gatcacggcg ttgttggaag aacgtaaacg cccggaatgg aatgccgagt tcgatcggga
     3121 cgagaaagag gaatacgata aggtaatcga gaaggaattg tatccgaccg agggtcaact
     3181 gaaaatgggc gaggtagtcc gtaaggtttc cgaggcgacc ggtaacgacg ctgtattggt
     3241 gaccgacgtt gggcagaacc agatgatggg cgtccgctat ttcaaatata aacaaacccg
     3301 tagcgtggtg acttccggtg gtttaggtac gatgggattt ggtctgccgg ccgctatggg
     3361 cgctaagttg ggagctccgg atcgtacggt ctgcttcttt accggtgatg ggggtatgca
     3421 gatgacgatt caggaattgg gcactatcat gcaggagaaa ctgaacgtga agattatcat
     3481 tcttaataat aacttcttag gtatggtacg tcagtggcaa gaattgttct tccacgagcg
     3541 ttattcaaac accatcatgg agaatccgga tttcgtggcg atcgctaaag cctatggtat
     3601 cgccggccgt gccgttgaaa agcgggagga attggacgac gctatcgctg agatgctaaa
     3661 ccacgacggc gcttacgtgt tggtcgctaa cgtggagact tgcggaatgg tatatccgat
     3721 ggttcctgcc gggggaagcg tgacaaacat gattatggga gacgagaaat aaggaggaga
     3781 tgaagctatg acaacaaaga aattatatac cgttattatc ttttcagaga atatcgtagg
     3841 tcttttgaac cagataacga ttatctttac acgccgacag ctgaacatcg agactctgtc
     3901 cgtctctccg tccgctatca agggcattca taagtttacg atcacgacat tcgccgatga
     3961 ggatatgatc gataaggtgg tgaaacagat cgataaacgt gtggatatct tgaaggctta
     4021 ttataatacg gatgaggatc tggtttatca agagatcgcc ctttataagc taagtaccga
     4081 gcttttcatc aagatgggaa ccgtggaggg attgatccgt aaatacaacg ctcgtatctt
     4141 ggagatgaac gagacctgcg tggtattgga gaagagtggc cactatgacg agacacaagc
     4201 cttgttcaat gagttgagcg agacgatcgg tgtcctgcaa ttcatccgct ccggacgtgt
     4261 ggctatcacg aagagcaagg tggagcgctt gagcgatatg ttggccgata tggagcgaaa
     4321 gttacatgaa aagcaacaat aataagatat ggagaaagta ggattatttc atttcgtggc
     4381 ggagccgtat ttgatggatt tcaggggacg tgtaacgctc cctatgattg gtaactattt
     4441 gattcacgcc gcttccagcc atgccggaga gcgtgggttc ggtttcaatg atatgtcgga
     4501 gcgtcatacg gcttgggtgt tgtcccgtct ggctatcgag atgaaggaat atcgataaga
     4561 ttaatctata cacttggatc gatgaggtcg gacgcctctt caccagtcgt tgtttcgagc
     4621 tggcggatga gaatgggaaa acctttggat tcgcccgttc tatttgggcg gctatcgacg
     4681 tggagacccg ccgtcctacc ttattggata tagaggcatt gggcaaatat atcgacgagc
     4741 gtccgtgccc gatcgagaag ccgggcaaga tcatgccggc ggagaataag gcggagggaa
     4801 tcccgtattc gatcaaatac agcgacttgg atatcaacgg tcacttcaat agcgtgaagt
     4861 atatcgagca cctgctggat ttgttcgata tcgaccagtt caagacccgt gagatcggcc
     4921 gtctggagat cgcctaccaa tccgagggta aacaaggtat gccgcttacg cttcataagg
     4981 cggagtccgc tcccgataag caagacatgg ctatttgcca tgagggaaag gcgatctgtc
     5041 gtgcggcggt tacttggaga taataaaaga gatacataaa taggttttta aacattaata
     5101 gttaaaaaga aaatggcaca aatgaatttt ggcggtgttg tagagaatgt aatgacccgc
     5161 gaggaatttc cgttggaaaa ggcaagagag atattaaaag atgagacaat cgctgttatc
     5221 ggctatggcg tacagggacc gggacagtca ttgaaccttc gtgacaatgg cttcaacgta
     5281 atcgttggcc agcgccaagg taagacttac gagaaagcgg ttgaggacgg atgggttccg
     5341 ggtgagactc tgttcggtat cgaggaggct tgcgacaagg ccacgatcat catgtgcttg
     5401 ttgtccgacg ctgccgtaat gtctgtatgg cctacgatga agccttattt gacagctggc
     5461 aaggccctgt atttctctca tggtttcgcg atcacttgga acgatcgtac gggcgttgtt
     5521 cctcccgcgg atattgacgt gatcatggtc gctccgaagg ggtctggtac gtctttgcgt
     5581 tccatgttcc ttgagggtcg tggcttgaac tcttctttcg ctatctatca agacgctact
     5641 ggcaaggcga tggatcgtac gttggcgttg ggtatcggta tcggttccgg ctacttgttc
     5701 gagacgactt tcatccgtga ggctacttcc gatttgactg gtgagcgtgg ttctttgatg
     5761 ggcgctatcc aaggtttgtt gttggcccag tatgaggtat tgcgcgagaa tggacatact
     5821 ccttccgagg ctttcaacga gacggtcgag gagttgactc aatccttgat gcccttattc
     5881 gccaagaatg gtatggactg gatgtacgct aactgctcta cgactgccca gcgtggcgct
     5941 ttggactgga tgggtccgtt ccacgacgca atcaagccgg ttgtcgagaa attgtacgcg
     6001 aacgtaaaat gcggtaacga ggctcagatc tctatcgact caaactctaa gccggattat
     6061 cgtgagaaat tggaggctga attgaaggca ttgcgcgaga gcgagatgtg gcagacagct
     6121 gttactgtac gcaagcttcg tccggagaac aactaatcca atcttaatcc ttatatatca
     6181 gcaaaaagag gcgggtcact tacgggtggc tcgcctttct ttgtgttatt cgatgtggat
     6241 attctttgtt ttcttgatct ttcgcatgct ggatgcggaa tggaagatgt ccagcacctc
     6301 gatccgttcc tcggtgatgc ggtagatgat aaggtgtgaa tctaggatga tgttccggta
     6361 catgcggctt ttcgtggtta ggtgtcggca ttcggggtaa taaggatagt cgttttctag
     6421 tttctcgact gtattcaata tatgctcaag atatttccgg gcttggaaca taccgaatcg
     6481 ttctatgcct tccacgaaag tcctctcaag gctttcctcg taaatgggag aaccgattac
     6541 ttttttcctt gatagctgtc catccatgat cttattcttt gatgtacttc ttcaatagga
     6601 tagaacggtc ccttctcaat ctcatggata tgttcccgga tctcttcttg ggtgaattgc
     6661 atcggcttgg taggatccca cttgggcttt gcgggctcgg tcttggcctt acgtgtcttt
     6721 gcggtcttgg ccgtagtttc cttggcgggg atgttgctta attttgtcat agtcgtaaca
     6781 gttatttatt agtacagtgg caaatgtatg gaataatttc catgtaataa gatatttggt
     6841 aaggaaaaaa gtaggtctat aggattaact tattacccag ttgtagaggc ggggcatgcc
     6901 ccgtctcatc tcctcaatag ggtagagaag cttaccttgc ctaagaataa aacagtattg
     6961 cgttccttga tgttatccgg taatacgctg ctcttgttcg tgaagaagat cgtagctcgt
     7021 taaaatgagc tgtctcacat atttcataac aatgcccatc ataaggtctt tatgatgggc
     7081 agcgtaagca gcttatactg cccatcgtta cgacccaacg atgggcagtg ttatttagta
     7141 acagatataa ttgtttatct tacgttttat aagaaatatc ctgtaaaaaa cttcgaatta
     7201 tatttggtgg tatcaaaaaa ggccgtatct ttgcgacgtt caaacaaaaa caataaagac
     7261 aagaacaatg acacgcaact tgcaaaatag tctcattatt tctctaaaca ttattctact
     7321 ctgggaacgg gataggaagt gagactgtat gctttgcgag cattacgata gatgaaagag
     7381 cctttctcac ttccttgtga gagaggcttt tttagttagt ataggatatt agtaaattaa
     7441 taatataaga ttatgtcaga cagattattt attttcgaca ccaccttacg tgatggtgaa
     7501 caggttccgg gatgccagtt gaatacagtg gaaaagattc aagtagctaa ggcattggaa
     7561 cagctaggtg ttgatgtgat cgaggctggt ttccctgtct ccagtcccgg ggattttaag
     7621 agtgtggttg agatctcaaa ggccgtgact tggccgacca tctgtgcctt gacccgtgcg
     7681 gtggagaaag atatcgacgt ggcagccgag gcgttgaaat tcgctaagcg aggacgtatt
     7741 catacgggta tcggtacttc tgattctcat atcaaataca agtttaactc aacgagagag
     7801 gagattatag agcgtgcgat cgccgccacg aaatacgcta aaaagtacgt ggaggacgta
     7861 gaattctact gtgaggatgc cgggcgtacg gataatgaat atctggcccg tgtcgtggag
     7921 gccgtgatca aggccggggc taccgtagtg aatatcccgg atacgacagg atattgcttg
     7981 ccggatgagt acggggcgaa gattaagtat ctgatggaac atgtggatgg cgtacataac
     8041 gctattcttt ccactcattg ccataatgac ttgggcatgg ctaccgcgaa taccgtacaa
     8101 ggcgtgttga acggagcccg tcaggtggag gtaaccgtaa acggtatcgg tgagcgtgcg
     8161 ggtaacacgt cattggaaga agtcgccatg gttttcaaga gccataaaga acgtgatatt
     8221 attaccaata tcacgacgaa taagatctat agtacgagcc gtatggtttc tagcttgatg
     8281 aatatgccgg tacaaccgaa taaagctatt gtcggacgta acgcgttcgc tcactcctcc
     8341 ggtatccacc aagatggcgt tttgaagaat gcgcaaacct acgagatcat tgatccgaag
     8401 gatgtgggta tcgatgataa cgcgatcgta ttgactgctc gtagcggtcg tgcggcgttg
     8461 aagcatcgct tgcatgtttt agg
//
