LOCUS       c00004_gnlPro..        14566 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EMCJDHFM_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:07:58
            Original ID  :: gnl|Prokka|EMCJDHFM_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14566
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14566
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[87:4566]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      88..4566
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14566
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14566
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(88..2934)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 5.3e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 3e-178, bitscore: 586.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3030..3410)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="GCV_H (E-value: 3e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3481..4566)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="GCV_T (E-value: 7.2e-87, bitscore: 284.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 5.7e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLATKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4642..5763)
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(5822..6745)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 1.2e-54, bitscore:
                     178.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGNSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7305..8432)
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWNGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLSPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPAGASTPLLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(8429..9541)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTASMADLLARWHAQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9538..10554)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10564..11625
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_9"
                     /sec_met_domain="Fer4_16 (E-value: 3e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11744..12121
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12155..12706
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12742..13353
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRSLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13486..14253
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_13"
                     /sec_met_domain="HAD (E-value: 3e-35, bitscore: 115.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYIFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 ttcggattgg aaatccgatt cttgaacata agaaaaaggc tgctccaaat gaatggaaca
       61 gcctttttga aaggaaggat gagattttta taactctacg gccttggaga attcctccac
      121 cgtgtcgcag gtgcagacca gattgcggtc tccgtacaca ttatccaccc ggcctacata
      181 cggccagaat ttgtgaataa ggagaccgga gaccggataa gccgcttcac tgcgggagta
      241 ggggtgccgc cattcgtcgg cggagaccat ttctgcggta tggggcgagt ttttcaggac
      301 gttgtcttcc ttgtctgccg taccgttgat aatggccgtg atttccgcat gaatgcgttc
      361 catggcttca atgaagcggt ccagttcttt tttgggttcc gattccgtcg gctccaccat
      421 cagggtgccc ggaacgggga aggacatggt ggggccgtgg aagccgtagt ccatgagcct
      481 tttggcaatg tcatccaccg tgaggccggc gtcatgagtg agctgacgcg gatccagaat
      541 gcattcatgc gccaccagcc ccttgttgcc ggagtagaga accgggaaga gatgtccgag
      601 tttcttggca atgtagttgg cgttaaggat ggccatttcc gtggcttccc tgaggccgtc
      661 cggccccatc atggagaggt acatccagca gatggcggcg atggaggcgc ttccccacgc
      721 cgcagacgct acggcccctt cttcatggcc cagcgtgagg tgcccgggca ggaagggtac
      781 gaggtgttcc gctacgccga tgggcccgat gccgggaccg ccgccgccgt gcggcatggc
      841 aaaggtttta tgcaggttca ggtggcagac gtccgcgcca atgcagccgg ggcaagtcag
      901 acctacctgg gcattcatgt tggcgccgtc catgtacacc tggccgccat tggcatggac
      961 gatgtcgcag agttccttga ttgtctgttc atataccccg tgcgtggagg ggtacgtgac
     1021 catgatgcag gagagattgt ccttatgggc ttccgcctgg gatttcaggt ctgccatgtc
     1081 gatgttgcct ctttcgtcgc atttgacggg caccaccttg aggccggcca tggcggagga
     1141 tgcgggattt gttccgtggg cggaggtggg aatgaggcag acattgcggt ggccttctcc
     1201 ggcgtgcttc tggtagcggc ggatggccag tagcccggca tattcccctg cggcgccggc
     1261 gttgggctgg agggatacgg cggcaaagcc ggtgattttc gccagacggt cggacaggac
     1321 ggagagcatt tcccggatgc cttccgactg gtccgccgga acaaagggat gcagggagtt
     1381 ggcttccggc cacgtgatgg gaatcatttc agaggcggcg ttcagcttca tcgtgcagga
     1441 gcccagaggg atcatggctt catttagagc caggtcccgg gattccaggc ggcggatgta
     1501 gcgcatcatt tccgtttcgg aatggtagga gttgaaagcc ttttccgtgc agaaaggcgt
     1561 ctggcgcgtg tggacgggat cccaggcagg agcgtcgcaa tcgcaggcgg cggatgtttc
     1621 cgcaccagca agggcggagg ccagtgccgc tatatccgca caggttgcgg tttcatccag
     1681 agagatggct gcgtggtcgg catccaccct gcggatgtta tacccggctt ccagggcttt
     1741 ttgcaccatg gcgtccgctt gtccgggaac ggacagcagc agggtgtcaa agaagttttt
     1801 gttttcaatg gcgatgccgg cttccgtgag cgccttgtac aggcttttgg ttttcaagtg
     1861 gatttccgtg ccgatgcgtt tgaggccttc ctggccgtgg tatacggcgt aaaaggcggc
     1921 aagcacggcc aggagcacct gggcggtgca gatgttggag gtcgccttgt cgcggcgaat
     1981 atgctgttcc ctcgtttgca gggccaggcg gtaggccggg cggcccaggg tatctatgga
     2041 catgccgata aggcggccgg gcatgcggcg tttgagagcg tccgtgcagg acatgtaggc
     2101 ggcatggggg ccgccgaagc ccattgggat gccgaagcgc tgcgtgttgc cgatgcagat
     2161 atcggctccg aaggcgccgg gttcccggat gacggtaagg gccatgagat ccgccgccac
     2221 gacgcagagc gcgcccgtgg catgcacgcg ggaaaagaag tccgtgtagt cgcagatgcg
     2281 gccgagcgtg tccggatatt ggacaagcac tccggccaga tccgcaccga tggatgcggg
     2341 gtcaaaggag gagcaatctc ccacgatgat gttaacgccc tggaaggcgg cgcgggtacg
     2401 gatgacgctg atggtctggg ggtggcaggt gtccgccaca aagaaggtgt ttgctttggg
     2461 gcgcgcgttc cggcacatgg tgactgcttc tgctgctgcg gtgccttcat ccagcaggga
     2521 ggcgttcgct accggcagcc ctgtcaggga agagaccatg gtctggaaat tcatgagcat
     2581 ttccagccgt ccctgggcga tttccggttg ataaggggtg taggccgtgt accagccggg
     2641 gttctccagt acattgcgga ggatgacgga gggagtgatg gtgccgtaat agccctggcc
     2701 aatgaaggtt ttcaggagct tgtttttccg cagaatggaa cggagttcct ccagggcttc
     2761 cgtttccgat ttggctgcgg gcaggtccag cggggccttc atgcggatat ctgcggggac
     2821 gatgtccgca atgagttcgt caagcgtccg gtagccgagg ctgtcaagca tttcccggcg
     2881 ttcttccccc tgggggccga tgtgccggct ggcaaaatct gagtgggtat tcatgtggta
     2941 tctctggctg gtaatagcgt ccggccgcgg aacgggccaa acaaaatgcc ccgggatgga
     3001 atcaccgggg cgggggaggg aagaatggtt caggagcagt attcctcgta atccgtggcg
     3061 ttcatcatat cttccgtttc cgtgggaacg tccaggcgga ttttgtacag ccagcctgcg
     3121 ccgtaggggt cggagttaat gagggacgga tcattggaaa gctcttcgtt cacttccagg
     3181 atttctcctg aaacgggggt gtacacgtcg ctggcagctt tgacagattc cacgacagcg
     3241 acagggtcgc cagctgcgac ggtggcgcct acttcgggaa ggtctacaaa gacgacatcg
     3301 gagagttcgg cctgggcatg gtcggaaatg ccgatggtgc cgatgtcccc gtcaatttca
     3361 atccattcgt gatctttgga atacagcaga ttttctggta cgtcgtgcat aagatgtaat
     3421 tgtttgaagt gagagtgtag taaaatgagg tgtttgtcag tttatttttg cgccgtagtg
     3481 tcagcctttt ttataaaagg gtttttttac gaccacggct gggaatttcc ttccccttac
     3541 gtcaatttcc agctccgtgc cgaccttggc atgggcggca ggcaggtagg ccagggcaat
     3601 gcccttcatc agcgaaggag agagcacgcc gctggtaagt tctccgatgg cttctccacc
     3661 ggggacgtgc acggcatagt gggcgcgggg aggagctccc ttgccggtgt attcaatagc
     3721 ggccagccga cggctgaggc cgttggcttt ttgttcccgg agaatatcgg aaccgatgaa
     3781 gtccgtatcc agcgcgcaga agaatccgag cccggcttcc agaggcgttt tgtccggaga
     3841 gaggtcggag ccgttcagag gatagcacat ttccagacgc aggctgtcgc gggcgcccag
     3901 gccgcagggt ttggctcctg ctccaagaaa ggcttcaaac catttgacgc cttccttagc
     3961 cgggcagaag aattcaaaac catcttcccc ggtatagccg gtgcggcaga taatgagatc
     4021 cgtcccttcc gccgtgatgc gggagattcc attgcggggg ggaagttcca cgccggggat
     4081 gacgcgggag aatacttctc cgcattcggg accttgaaca gccagcccca cgtattcgtc
     4141 ggagtggttt tccagagtta cgcctgcagg ttgatgggcg gaaagccatg cgaagtcttc
     4201 atcaatcttg gaggcgttca ccactacgaa gaaggtttcc ggttccatcc ggtacaggat
     4261 gaggtcgtca atgactccgg ccctgtcatt gagcatgacg gagtattgcc cctgccctac
     4321 attcagtttg ttgatgtcat tggtcagcat ggagttcagc catgccgcag cggaaccgcc
     4381 ggctaccgtg aactgcccca tgtgggagat gtcaaaaatg ccgcaggttt cgcgcactgc
     4441 tttgtgttcg tccagaatgc cggtgtactg caccggcata ttccagccgg cgaaaggaac
     4501 cattctggct cccagttcaa cgtgtttagt tgccaggggg gtggatttga cgtctgtatc
     4561 agtcatgagg cgatgtgaag gttatgagca atctgcccct tatatcagta aaagtcaatg
     4621 gaattccggt aacgcttccg tctagacatt gaagcggaat tcgatgacgt ccccgtcttt
     4681 gacgacatat tcttttcctt cgatgcgcag cttgccgtgt tccctcgctc cggccttgcc
     4741 gccgcaggaa accaagtcgt cgtagtgcac tacctccgcg gcgataaaac cgcgttcaaa
     4801 gtccgtgtgg atgacgccgg ccgcctgggg tgcttttgcc ccggccggaa tggtccaggc
     4861 ccgcgtttcc ttgattcccg tggtgaggta ggtgcgcagg cccagaaggt ggtacacggc
     4921 gcggataagg tcggaaacgc cggagtcctt cacacccagg gattccagga attcgcggga
     4981 ttcttcctcc gagacgtcga tgagttcctc ttcaatccgg gcggagatga caatggcttc
     5041 cgcgttatgg tgttccgcta cgtatttttt cacctgggag acgtagggat gggcgtccgg
     5101 gttggagatg gcgtccgcca gttcgtcttc attgacattg caggcgaaaa tgcttttttt
     5161 atccgaaagc agctggaaag aatggagcag cttgcgttca tcgtcgtcca gctgcggttc
     5221 aagggtgagg gcgggattgc cttcgttcag gtggggcagg agtttggtga tgagggccac
     5281 ttcggccttg gcttccttgt cgccgctgcg tgccttgcgt tcgcgggaag agagtctctt
     5341 ttccatggtg gcgatatccg ccagaatgag ttccgagttg atgatgtcaa tgtcgcgcag
     5401 aggatccacg gaaccgagtt catggataat atcatcattg tcaaagcagc ggactacctg
     5461 cacgatggcg tccacttcac ggatgttcgc cagaaactgg ttgcccaggc cggctccttc
     5521 cgaggctccc ttgaccagac cggcaatatc cacgaattca ataagcgtgg ggatgatttt
     5581 ttcagaaccg gacatgtcgg aaagaacctg caggcgggga tccgggactg ttaccatacc
     5641 cacgttcggg tcaatggtgc agaagggata gttggccgcc tgggccttgc gcgtccgggt
     5701 gaccgcattg aatagagtgg atttgccgac gttggggaga cctacaatac ctgcctgtaa
     5761 cataggcagg actgatagcg ggtcacgccg tgaaagtcaa ataccaattg ccgacgggca
     5821 tttatgcggc ggatcccaga gcccatctga tcaggttttc cgattccgtc cagatacggg
     5881 acggatggca gccgaggacg acgacgatga catggcgccc gttgacgccg gctgaggaaa
     5941 ccaggcagcg tccggcggcg ttcgtgtatc cggttttcat tccggtaacc caggggttct
     6001 gggtgagcag cttgttggtg tttctcagca gaagcgttct gccgttggcg cgggtaaagg
     6061 catattggcg tttgcagata atattgcgca gttccgggtt gcggtacaca taataggcgc
     6121 agcgggccat gtcaatggca gtggaatatt gatccgccgg gaggccgttg ggattggcga
     6181 agcgtgagtt gtacatgccc atctgccggg ctttggcatt catcaactgg gcgaaacggg
     6241 gaacggaacc cgccgtatcg cgggccagag ccagggctac gtcgttgaaa ctgcggatca
     6301 tcatggcatt gagcagttcg cggcgtgaat agacttcccc cgcccggaat cccagtttgg
     6361 tggggtccgc cttggtatcg gaaggctgga tgaccacttt tttgtccagg ctgccgtgtt
     6421 ccatcacgac catggccgtc acgagtttct gcgtgctggc tacctggcgg tgctggaggc
     6481 cgttgtggga aaagagcacg ttgccggtaa gggcgtccat gacgcaggcg ctggcgcagc
     6541 ggggcgtgcg tggggcgctt gaggggatgg ctacgggacg tgtggggaaa ttggccggtc
     6601 gggggagggc atgggaaacc ggctgggaga gttgtggggg aacgggcgtt gcaaggggga
     6661 tgtagtcact tgaattcccg tacgattggc agcttgtgga gctcaggcaa agggagaatc
     6721 ctgcaagaag ggcgaataaa cgcatgtctt gttgctacag taagaagttt cgttcatcaa
     6781 gcccaaactc cgcatttgaa agagagccgg acgaaaaagg ccgcggatcg gacaatccgc
     6841 ggcctttttt ctctattaac tacctatgga accaaaaacc accctgaacg gattttgaat
     6901 tgcttttccc atccgtcgga cagatcttgt gaaggatgag actccaggca ggagtgatgc
     6961 gttcaaaata tgttcgtcaa caattctttt taagaggtgt tgccgtatga gcccgagcct
     7021 gcgtccagta aatatggcag agattttttc cgaacatatt ttgtttttcg cgagcatgta
     7081 aatttaccgc aggcatttaa aatgccgggg atgtcctgcc gatatattta atttttggaa
     7141 taaaattatt gaaggaaagg atttggcgac tgttttaaga cgtttttttg catccggatg
     7201 gaaaggtttt tatacgggag atggacggcg ctcccttccg gttccatggt cagggagagg
     7261 aggcccggac ctggcgtttt ccccggcgga aaagcggaat cttcctaaag ttccctgccg
     7321 ttaatggaga aataccctcc ggcgtccgga gtaatttgcc ctgcaatttg cattttggcc
     7381 aaaagcgggg tgatggtatg cgccgctttt cccagagagg tgcagagggt gtcaatagta
     7441 ttgaaaccca gtctgatggc gtggagaatc tccttttctt ccaaagtggg aagcagtggg
     7501 gttgaggctc cggcaggggg acatggcgag aagagaggca gtccctgttc cggaacggcc
     7561 cagttcatgt cctgcagaat atcggaggct ccggtagcca ggatggctcc gtcccggatg
     7621 agggcatggc atccgtcgga agaatgccgg tcaaccggtc cgggaatgca gaaaacctct
     7681 cggccctgtt cggccgccgt tcgggccgtg atcagggccc cgctgcgtcc ggacgcctcc
     7741 accaccagcg tagcgcggct ccagccgctc acgatgcggt tgcgcatggg aaaagtggtg
     7801 cgggaggggg acaggtccat tgggaactcg gagactaccg ctccatgccc gtccgcaatg
     7861 cgctgcgcca agtttctgtt ttcccgagga tacagtttgt tgagacctgc cccgataacg
     7921 gcgatggtgc gcccctccgc gtccatggcc ccggtatggg cttccgtgtc cacaccgcgc
     7981 gccagtccgg aaatgacggt gactccggct tccgccaggt catgggagat gtttctggcg
     8041 caaagcctgc cgtaatgggt ggccatccgt gagccgacga cggcaatgga gcgttcggca
     8101 tccgttccgt tccagtttcc ccaggagtag aggacaatgg gcgggtctgg gagagcacgc
     8161 agggaggatg ggtaggagtc gtcaaaaacc gtggttactg cggcccccgc gttatccgcc
     8221 agttccagtt ccctgtacgg gttgacgatg ctccgccaag aggaaatgcg gcaagccagc
     8281 tgcgccccca cgccgggaat ttccatcaac agggaggaag gggattccag aatcagttcc
     8341 ggagaggcga atacctgcag gagacgcatg attctgacag ggcccaggcc cggtatcagg
     8401 ttcagggcta tggctgcttc ccggggtgtc atgaataagg ggtcagttcc tggtaaacgt
     8461 ccagatgggc ttgaatcata tcctgcatat tgtaagggga aggaatttgc cggggcaggg
     8521 gggggggctg ggcatgccag cgggccagca ggtccgccat ggaggcggta tctcctacgg
     8581 cgacgttccc ttcaggaagg aaggcgtcca gctgttcctt gactccgccg tgggcgtatc
     8641 cggccacagg tttgcccagg gcgagcgcct ccagggttga tttgccgaag gcttccgggc
     8701 ttttggtcag ggagagggtg acggaacatg tggaaaggat ttccctcaga tcctggcgat
     8761 gtcctgtcca ggtgaaggac tgggagacgc cggaacgttc tattgcccgc aggacctcgt
     8821 ttttatattc ttcttttccc ttctttgctt ctcctacaat gacggcgtgg gccgggattc
     8881 cctgttccag aagctgcctg acgaccggaa tcagatccag atgccctttc aggcgcgtga
     8941 tgcggcccgg caggcacagg gtgaatttcc ccttcagttc aggataggac atgaaccagc
     9001 ccgtgagcca ttcccgggag ggggagtagg ccgggtgata ttggtccggg gaaatagcat
     9061 tgggtatgat tctgatatgg tccggagggg tggacggata atggtcaagg atgtagtccc
     9121 tgatgcagtt ggagacggcg atcacccgct ctccccggct catgatggcg gagtaccggt
     9181 tgacggagta gaagccgtga acgctggtga cgaggccggg acggtcttcg ggcgggagct
     9241 ttttccatgc caggtagcct gcccacgcag gaacgcggga atggagatgc aggatatccg
     9301 gcctgacggc ctgaagcagg gcgcggaggg ccccgatgcg gaagagagtg gagatgcttt
     9361 ttttgcctat cggcatcagg atgtggcggg agccttcctt ttccagacgg ggcaccaggc
     9421 gtccgcctcc ggaaacgacg atattttcca cgccccggga agaaaggccg ctgcccagtt
     9481 ccataacgac ttgttccacg cctccggatt ccatggaggg gacgagatgt actattttca
     9541 taaggcgcgg agctgaggga aaaatctgga gaggatgtag tctgctgcac ggtccgcttc
     9601 cagaagcggg gaaccgggag ccgtcaggcg gaagttctgt tttttccagt cactgtatcc
     9661 agtaaccatg ccttcctttt ccagtgtctc caggccggac aggatgcggg atttgcggct
     9721 gccgtgtcgg cgcggtacgg aaaggatgcc tacaggcgcg ccggagccaa gagcctcata
     9781 taccatggag acgctgtcct ggctgaccca ggcggcggag gcgtgcgcca gatgccgggc
     9841 tacccacccc ggccgggttt cctccacggg aacgacggtt agttccggaa cggccgtccg
     9901 gattttttcc gcaaagccgt ccggcgtccg gcgcgaggtg gttagaacaa ggtgtccggg
     9961 ggtgtggatg ctgatggacg cgagctggtt gagcatgctt tcgtcatccc agtcaaaatc
    10021 tttgctgggc cctcctatga gaatcagtgt ggtatccttt ggtacggagg gatccggcct
    10081 catggggtgg agagctccct gggtggggaa gatatccgta tccgtgtaat cgcggccgga
    10141 atccaggtca tggcggggaa taaggcagag gtcgaaaaag gaacagggaa gcgtaggctt
    10201 catgcagagg acggcccggg ttttgaaatg gtgccgcgcg cagatgagcg ggatatgcgt
    10261 tgcatgtccg gcggaaatga acagatccgg ccgtggaatg tcgctgcctg tgacgacctt
    10321 ccggattttc cccaaaaggg aaagcccctg caggtctacc gtttccacgg ttccccccgc
    10381 tttggagatc agagcctgcg ccagccccag ggactggttg aggtggccct gtttcccatc
    10441 gctcagaatc cggatgttca tatatgcggc attatgaagc ggcggcgggg tgcaggcaat
    10501 ccaatttcca ccggacagaa gaaaattctt ggtgggaggc atgctcttgt tcatgattcc
    10561 ggcgtgctga ctccggattc ctctgttatt aaagattcct tgtgcgccgt gtcccggcag
    10621 cttggttttt ccggctgccg ggtggcccgt gcggaaaaaa gcccgcatgc ggaaaaattg
    10681 tttcaatggc tggagcgcgg atggcacgcc gggatggagt ggatggcgcg ttccccggag
    10741 cggcgcacgg atcctgcgga agtgcttccc ggatgccgtt cagtcatttg cctgtcctat
    10801 gattatgaca gccccggtag gcgcccggag ggggagggta gcatttgcct ttacgcccat
    10861 ggaaaggatt accacggaat tctggaggaa aaactggcgg atttgcagga gctgctttcc
    10921 atttacggcg ggaagcagag ggggtatgtg gactccggcc ctgttatgga acgggaccat
    10981 gcggaggcct gcggcctggg ctggcgcggg aaaagcggtt tgatcgtgcg caggaaaggg
    11041 ggctcccgct tttttatcgc taccctgctg actacgctgg aactggaacc ggacgctccg
    11101 gtttcaaacg gatgcggcag ttgccgccgt tgtgcggccc tgtgtccgac gggcgcaatt
    11161 atggaaaacg gtcaggttga tgccggacgc tgcctttcct actggacgat tgaacaccgg
    11221 ggggctattc cggaagaaat ccgtcccctg ataggcacgc gcctgtacgg gtgcgatacc
    11281 tgcgtgacgg tctgtccctg gaatggtaag cctttgccgg acgttgacga acggttccgc
    11341 atgtcccgtc tgctggcttc cattcccctg cgtggtcttc tttccctgga tgccggcggt
    11401 tttgcggccc tgttccggaa ttccccgttg aaaaggctca agagggaagg gctgctgcgt
    11461 aacggctgcg ttgtgctggg gaatgcgggg actccggatg acattgattt tctgaaggcg
    11521 ctttacgggg agtctcctct ggtggaggaa cacgcttcct gggctgtgga gcgcatcctc
    11581 cgccgccacg ggcggcatgc atcttcaagc ggtgcaagag attaaaaata gaaaaaatga
    11641 tgttttggtc ttgtcaaaac ctcaatttat ggtatccatc ttgccccaag caatagctct
    11701 gcgcgaggca gagaaaaata acagctagca aatccaatcc attatggcac gccttttcgg
    11761 tacagaaata cccaacgaga agcgcatcga ggcttccctt ccgtatattt acggaattgg
    11821 tcgctcgact tctaagagaa tcctggaaca agcaggcatc aatcccgaca tccgcacggg
    11881 acagcttacc gacgaacagc tcacgaagat tgttcaagta atcaccaccg acggcatttt
    11941 gattgaaggt gaccttcgtc gtgaaaagca atccattctc aagcgtctga cctccatcaa
    12001 ctgctatcgt ggtcagcgcc accgccgcgg ccttccggta cgcggtcagc gtacccgcac
    12061 gaatgcccgc acccgtaaag gcaagaagaa gaccgttggc gcgcaggcca agaagaagta
    12121 atccgccaac ctgaattttt aatatagctt tactatggct agcgaagaaa tcaccaacga
    12181 aaccgccgaa cagcctgtgg aagcggcagc ttccgctccc gtcgctgaaa ctccggccgc
    12241 cgctgtttcc gctcctgaag aaatcaagaa gcccgaaccc cgcaaggata tctttgcgga
    12301 acttggtctg ggcggcgatg atgacaagcc caaaatcctg aaggccaagg gcagcaaaaa
    12361 cgtttccacg ggcgtggttc acgtttcctc cacgttcaat aacaccgtcg taactgtgac
    12421 tgaccagcgc ggcaatgtca tcggctggtc ctccgccggc aagatgggct ttaagggttc
    12481 ccgcaagagc acggcctatg ccgggcaggt ggtgtgccag gacgcctgcc gccaagccat
    12541 gggccacggc ttgcgtgaag tggaagtgcg cgtaaagggg cccggttccg gtcgtgaatc
    12601 cgctgtacgt gccgtgcaga cgatcggtat tgaaatcacc tccatcaagg acgtgacccc
    12661 catcccccac aacggctgcc gtcctccgaa ggcccgccgc gtctaattga gaatctttta
    12721 cctatataga tctaatatat catggctcgt tataccggtc cccgcgataa agtgtcccgc
    12781 cgttttggcg ttgccctttt cggttccacc aaggctcttg aaaagcgccc cttccctccc
    12841 ggccagcatg gcatgcgcgc cggccgcaag aagaaatccg actatggcgt gatgcttgct
    12901 gaaaaacaga aactgcgttt ccagtacggt gtgcttgaag gccagttccg caagtattat
    12961 gcagaagccg cccgccgccg cggcattacc ggcgatattc tgcttcagct ccttgagctt
    13021 cgtctggaca atgttgtgta ccgcctcggc ttcagcaata cccgtgccgg cgcccgtcag
    13081 cttgtttccc acggccacat caccgtgaac ggcaagaaga cgaatatcgc gtcctactcc
    13141 tgccgtccgg gcgacgtcat tgccgtaggc ggcaaggctt cttcccagca gctggttacc
    13201 cgttcccttg acctgactca ggctactgtg gttcctgact ggctggaatg cgaccgtgac
    13261 aagctcacgg gcaagattgc ccgcgtgcct tccaaggaag agattgctcc catcgtcaat
    13321 gagcagctca tcgtggaatt ctactcccgt taatcttatt tccttctgga tttgcttcaa
    13381 aaccccggtt gcctttcggc ggccggggtt ttgggcattc agggggggag gggcatggaa
    13441 gagttgggtg ttgagagtta agggaagctg gtataggatg aaagcatgac ggacgattgg
    13501 aaaaaaagag gcgcagcgct tttcgatatg gacggcacgc tccttccctg ggatacgcaa
    13561 tatatttttt cctgttttgt ggtgaggcgc catccttgga gacgcttgct gatttttctt
    13621 ttcctggcct gtatcccgct ctatattttg agaatatggg atgagaaccg gatgaagagg
    13681 gcttatctca tgtatttgtg ggggcttccc gctgaaacgg tgcgggaata tggacggaag
    13741 tttgccgaga tggcgcagga atggatttat ccggagctga aggagcggct ggcagggtat
    13801 cggaagaagg gttatttgtg tctcatggtt tccgcttctc catcatttta cgtgaagccc
    13861 ctgggcgaac tgctgggatt tgacgaagtt ctgggaacgg atgtgcttct ggaggaacgc
    13921 atgccggcaa tgccggaact gccgaacggt aataataagg gggcggtgaa ggtggagcgt
    13981 ctgcgggagc ggaatgtact gccggaacat ggtgttctgg aaaacgccgt tgcctacagc
    14041 gacagtgccg cggatctgcc catgctgctt tcctgcaggc ggagggttct ggtgaatcct
    14101 tctcctgccc tgaaagaaga caggcttctg gatggtgcgg agtgtctgta tccggccagg
    14161 ccttggaagg gaaggtttgg caagatatgg agaattggat tttttgtcat ggggttggtg
    14221 gatgtaaata atgtgaaatc aatgacttgc tgatttatca agagaaaatt ctttactttt
    14281 gtgacgaaaa tgtttcactt ttcttaacaa ggggggaaaa agcatttttc tttccatgtt
    14341 agcaaatcaa caattaatac cctaaccaag taatagtcat gcaaaccaag aacatcatca
    14401 gtgttgcggc agttgtggca tcctttgccg gagctgctct tgcgggtact cccgtcaaga
    14461 ttgttgctcc gactccggtt cccgctcctg tggcgacttc cagcccgctg tccggcgata
    14521 tttacgccgg ctacgcttcc aattacacct gccgcggcat tgtggc
//
