LOCUS       c00024_gnlPro..        14145 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BCKNFMHC_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:23:30
            Original ID  :: gnl|Prokka|BCKNFMHC_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22550
            Orig. end    :: 36695
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14145
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32550:36040]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14145
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14145
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(470..1060)
                     /locus_tag="ctg24_30"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPILVQRIFQSDQQNEAKAAAE"
     CDS             1363..2910
                     /locus_tag="ctg24_31"
                     /transl_table=11
                     /translation="MTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIV
                     GYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANG
                     YQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLD
                     LLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDV
                     RFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVF
                     KFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKI
                     LAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGS
                     FLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKH
                     YEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             2974..3162
                     /locus_tag="ctg24_32"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLA"
     CDS             3298..3492
                     /locus_tag="ctg24_33"
                     /transl_table=11
                     /translation="MEKRMEMLDNRCRQEGKRLFEARYYGSAASKDILENSDEFSDLVE
                     PDENGAPPDALWENEEAGQ"
     CDS             3592..4365
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_34"
                     /sec_met_domain="adh_short_C2 (E-value: 3.3e-75, bitscore:
                     244.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLNTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4389..5594
                     /locus_tag="ctg24_35"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAADPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMIAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             5728..5976
                     /locus_tag="ctg24_36"
                     /transl_table=11
                     /translation="MRVSPSFIPEQDAVAIHGSRIVGNIVDATSVIRADDGKEYEVLGM
                     GPIAVLPEYQRRGIGRRIIGMRQPSRSVSCKGDPYPA"
     CDS             complement(6271..7011)
                     /locus_tag="ctg24_37"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7306..8013
                     /locus_tag="ctg24_38"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg24_39"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGE"
     CDS             complement(8710..9525)
                     /locus_tag="ctg24_40"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg24_41"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_42"
                     /sec_met_domain="SucD_FumR (E-value: 1.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10751..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_43"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.3e-38,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_44"
                     /sec_met_domain="Fer2_3 (E-value: 8.7e-24, bitscore: 75.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.3e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.4e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNESLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(13487..13723)
                     /locus_tag="ctg24_45"
                     /transl_table=11
                     /translation="MGPSLSDGACLGFVRHFQVRSPGLLEPFRCNNFLRCATMRKQLSG
                     ILFLVQGNLIMKKTPDSRCRREFLQSVLRRNLL"
ORIGIN
        1 tttctgtaat gccgtgacat ggaacaagaa aatctcttga tttctacttg ccaccattta
       61 cattggtgcc agcaaacctc cgtggatgcg gaggttccag tagttaacaa acactgtatt
      121 taattcgaat tatgaagaac atcgctatcc tcgccatcgc cggcgccgct tgcctggtcg
      181 cttcctgctc ccagcagcag cagcaacagc aaaccaccgc tcctgctccc gctccggttg
      241 tgcaggccaa gggcaagtaa gtttgcagcg gggttttgcc ctgcaacact agcaaattat
      301 ccaattaatc cgcactcggt gtacgcactg agtgcgtttt tatttgccct gagtccggat
      361 tccctccgcc atttgccgat tcgccgggat tttccttaaa aacggcggat accgcaaacc
      421 gccgcggcgc agcaccgtgt gccggttcct gccggatcag gcttcccctt tattcagcgg
      481 ccgccttcgc ctcattctgc tgatcggact ggaatatccg ctgaaccaga atggggcgtt
      541 tcctggccca cccgggccag accaggtgat gttccatgcc gtaggaatgg ccctccggaa
      601 aggccttgga aacaaatggt tcccgccagt cctcctccca tttgccgcct tcccggtcct
      661 tctgggtcag cgtcaccaga tgcccgcagt tcttccaggc atccagaaca atggagccct
      721 gcaatccctt ccccgcggca ttgacataca cgcaactgtg ctccctgccc gttccacggt
      781 ctcgaatcgt cagccctatg cggaaatact tcacggggcg gcggcgcagg tcccggtaca
      841 aatcctgctg gacctgccag cacagccccc tgtcgcgcag gttggaattg accagaatat
      901 tgttcagcca gccaaacagc acagtcctgt tgtcccgggc aatcgctgcg gactggacca
      961 cggccgtgtc cgccagccac ctggcctccg ctccggcagc gggaagagag gcctgatccg
     1021 gcggcagcag cgccaggaag gcattagcca gcccggacat ttgctgctgc acgtaagttt
     1081 gttgtatata atcctccgcc ggaggagtac agcaggaact ccatccgcac aaaagggcgg
     1141 cagcaagcaa aagcctgaat gtctgcgtgg tcggcatggc gcgccaaggc tagcagacta
     1201 cgcgtaaaaa tccagtaaag ctttcaaaaa tgcctgcctc cgccctgacg gctcttgcct
     1261 tcccctttcc atcccggtag aatacatcct ctcttcacca tgctgacgat caaaaatctc
     1321 acaaaatccc acgccggacg gaccttgttc agggaaacgg aaatgaccat taactggggg
     1381 gaacgggtgg ctctggttgg ccccaacgga gcaggcaaat ccaccctgtt ccgcatgatt
     1441 ctgggagaag acacgccgga cgaaggctcc atcagcatgg atgaatacgc catcgtgggc
     1501 tatcttcccc aggaagccag cgaaccgaag gatgaaaccg ttctggaaat cgccctgggc
     1561 atcacgccgg aaatggaaca ggccatccac accatccgga cggcggaaaa cgccaacaaa
     1621 acggatacgc cggaatacgc ggaagccatt gacactttca acgccgccaa cggttaccag
     1681 ctggagccca aagccaagaa aattctcaaa gggctggcct ttcgggaaag cgacttccat
     1741 cgccccgccc gggaaatgtc cggcggctgg atcatgcgcg cgtacctggc caagctcctt
     1801 gtcctggagc cggacctcct gatgctggac gaacctacca accacctgga cctcctgtcc
     1861 ctgctgtggc tccagcgata cctgaaaaac taccccggag ccatcctgat gatttcccac
     1921 gaccgggatt tcatggatga gctggtggaa agcgtgtacg acatcgacaa cgaagaactg
     1981 gtggaatacc gcggcaatta ctcggacttc ctccaacaaa aggacgtgcg cttcgagcag
     2041 cttcaggcgg cctaccgcaa ccagcagaag gaaatagcgc acattcagga atttattgac
     2101 cgtttccgct ccatcaattc caaagccggg caagtccaga gccgcatcaa gcagctggaa
     2161 aagatgaaaa tcattcaaaa accggtagcc cgcaggaaag tatttaaatt caacttcccc
     2221 cagcctccgc gcagcaccca gaaagtcatt gagctggaaa aagtctgcca atcctatggc
     2281 gaccgcaggg tttatgaaaa cctggacctg ctggtggaac gcggggagcg cactgttctt
     2341 gtaggcccga acggcgcggg caaatccact cttctcaaaa tcctggcggg catcatcccc
     2401 attgactccg gacaacgcac tcccggtacc acgacgcgca tcggctactt ctcccaggcg
     2461 cgaacggaaa acctgaatcc ggaaaatacc gtgctggagg aaatcatgaa atgcagcgct
     2521 gaaatccggg aggaagaagc gcgttccatc ctgggttcct tcctgttccg gaggctggat
     2581 gtagaaaaac gcgtcagcgt tctttccggc ggggaaaaat cgcggctcag cctggtcaaa
     2641 ttcctggtgg atccgcccaa cctcctgctg atggacgagc cgaccaccca cctggacctt
     2701 ttgtccgtag aagccctggt gcaggctctg aagcattatg aaggaacact ggtcttcatc
     2761 tcccacgatg tgcacttcat ccgttccctg gcacaaaaaa ccctgcatgt gaaccggggg
     2821 accatcaccg cctacgcagg cggatatgac tactatctgg aaaagtcagg cattctggac
     2881 gatgaaaaag gcggcatcac ggcggaataa ggctcttttt tcagtttccc ctttttcctt
     2941 gccgtggatt tcatcctgcc ttaaaagaac aggatgaagg cttttcttgt tcctctctta
     3001 tattctgcgc ttctgtccgg agcctctctt gcatttggtg aaacggccgc cggaacggct
     3061 tccccctcag cagcggctcc ggcggaaaaa attccttccg cggaatccct gatcaaccag
     3121 gccttttcct ttgccatcaa tatccagcag acgttggcat gagttcagga caaggaaagc
     3181 gcggacaacg ccgtcaaaac gctgcaggac attcagaagg acatccggca tttcctccag
     3241 cttcaggata aattgaacga tgcggaaaag gagaaagaag acgccttgat agaaaaaatg
     3301 gaaaaacgaa tggaaatgct ggacaaccgc tgcaggcagg aaggcaaacg cctgtttgag
     3361 gcccgctatt acggttccgc cgcctcaaag gacattttgg aaaattcgga tgaattcagc
     3421 gacctggtag aaccggatga aaacggtgcg ccccccgatg cactctggga aaatgaagag
     3481 gccggacagt agccccccgc cccgtttctc ccccctcttt ttcattcccg gcacgccctt
     3541 tccccgtatg ggttcctgcg cggccaagtc catttcaagc ttgccggaac cgtgaaaaac
     3601 gggtttactg tgggcagcat gcaaaagtta gcaggtaaaa cagccatcgt taccggcgcg
     3661 ggccgcggaa tcggcaatgc cgtcgcgcgc cgcttcgctt cggaaggagc cagggtcatc
     3721 ctgatcagcc gcagtccatc cagctgcggg ggggccgcag aagaaatcaa caaggaattt
     3781 ccggattcct gcaaggccta cccctgcgac gtagcggatt acgcggccgt tcaggaaacc
     3841 atggccgcca ttttgaaaga cttcccgcag attgacatcc tggtgaacaa cgccggcatc
     3901 acgcgggact ccctgatgct ccgcatgaag gaggaagact gggatgccgt tctgaacacc
     3961 aacctgaaaa gcgcgttcaa tacagtcaag gccctccagc gcgttctcat gaaatccccg
     4021 gccgggcgca tcatcaacat gagctccgtc atcggtctcg tcggcaacat cggccaggct
     4081 aattacgccg cttccaaggc gggcctcatc ggtttcacca aatcactggc tcaggaattc
     4141 gctccgcgca aagtcacgtg caacgccatt gctcccggct tcatctccac ggaaatgtcc
     4201 aatgccattc ccgacaatct caaggaagaa atcgttaaga aaataccttt gaaagaacaa
     4261 ggttccgtgg aagatatcgc cgccctgacg gccttccttg cctctgacga tgcccgttac
     4321 atcaccgggc aggtcattgc ctgcgacgga ggcatgacga tgtagggcat tccggttttc
     4381 accattccat gcgcggcatt ttccttgttt cctgctttct gggaggaagc gccctgctgg
     4441 ccgggtgccg ggaagaaaat aattcccccc gcccggccac ggaagatgcc gcgcgcatta
     4501 ccagcgcacg ccagtgggga gaaagccgat ccgcgctgca aaaacgggaa ctggaccgcg
     4561 ctgccgatcc tgcccttccc attccggatg acctgccgtc ccgggagctg gtcggcacga
     4621 cgcgccaaat ccatcagctc attgaagctt ccggaaatcc ggcacgtttt gaatcctaca
     4681 cggaaacggt tcccgcggcg ggagcttccc tgcgcatgat cgccataccg ggaggaacgt
     4741 tcctcatggg gagtcccgcg gaagagccgc accggaaacc ggacgaaggt ccgcagcata
     4801 aagtgagcat ctctcccttc tggatctcgg aaacggaaat cccctgggaa ctttatacgg
     4861 ccttcatgga aaacgggcgt ccgcgcgcca aggacggcca gcttctggag gaacagccgg
     4921 atgacgaact gtgggactcc gtcacgcagc ctaccgcccc ctacgccgcc atgaacctgg
     4981 gcatgggcca cggctatgaa cacggcctgc ccgccatctc catgtcccac cacgccgcca
     5041 gcaaattctg cgaatggctg agcgcccaga ccgggcatta ctaccgcctg cccacggagg
     5101 cggaatggga atacgcctgc cgggccggtt ccgccggcgc ctattcttac ggaaacgggg
     5161 aagcctctct ggaccagtac gcctggtact ggaacaattc caatgaccgc taccagaaaa
     5221 caggctctaa aaaaccaaat aagtggggac tccgggacat gcacggaaat gtggcggaat
     5281 gggttttgga ctcttacgtt ccggatgcct acggcaaacg gagcggcttg cccgcgaaag
     5341 accccctagt catcatcccc ggcgcccctc acatcgttcg cggcggttcg tgggaagacg
     5401 acccggacag cctgagaagc gctgcgcgcc gcgccagcac ccccgcctgg aaccgtcagg
     5461 atcctcaaaa ccctaaaagc atctggtacc tgacggacgg aggcatgatc gggttccgcg
     5521 tggtgcgccc catgaacatt ccggacatta tgacgatgca ccgcctctgg aatttctcca
     5581 agggggagcc gtaaagaaca atctttcatg accattgcat taagaacgga acaatcctca
     5641 gaccatgccg aaacggaaca tgtcacgaga gaagcgttct gaaactattt cgtccccggc
     5701 tgcaatgaac attacctgct ccatatcatg cgcgtcagtc cttccttcat cccggagcag
     5761 gatgcagtcg ccatccacgg cagccgcatc gtcgggaaca tcgttgatgc aacgtccgtc
     5821 atcagggcag acgatggaaa agaatatgaa gtgctgggca tggggcccat tgccgttctt
     5881 ccggaatacc agcgccgggg aataggacgg cggataatag gtatgcggca gccctccagg
     5941 tctgtgagct gcaaagggga tccctatccg gcctgaaagg ccgctatgtg aaagctgccg
     6001 tgtaccatat ggacgaaaag cgcgctgccg aatttgacgg cattttccgg taaagaaaaa
     6061 gctttccggt actgcgtctc aaaaacgttt ccagcaaatt gccgccatgc ggaaaaaacc
     6121 ggatacggcc ccctgccccc ggaaattccg taccttccgg agggcatgaa tcccgcatac
     6181 ggataagcaa ttcttcctct ctggatataa aaaacaagag ctgttccgca agaacagctc
     6241 tcatccgccg atttttcgcc atcaggaagc tcaagccctg cggcggcgca tcatcagcgc
     6301 agccagtccc agcaggccca gggaaaccgt ggctggttcc ggcaccattt cccctcggat
     6361 ttccgtgaaa atcggggata ataagctgaa agtattggtt ccgttggctc ccgtaataac
     6421 gacagaatca ccaggcgctc cctcggcgtc ataatggccg cggatgccgg gagcagtcaa
     6481 tccgccgctg atcgttacgg tatctccttc cgtgttagca gtaggggcgg ctgttccccc
     6541 cgcagcatat aaatacgttt tagacgtatc ctgcatcaag tccatcacgg actggctcac
     6601 ggccaggaaa cggtatgtca atgccgcgtc aagaagcagg ggagaaccat ccagggaaga
     6661 aaaactgaac gtcagattaa tccctgctgc agtagttccc gtattggtgc tccagccgat
     6721 gaccgaattg tcggagccat tcagcaccag gaagccgtaa gtgacattag cgcccaaatt
     6781 gttggcggct ccgcgcagcg taaaactgtc cagtctgatc tctccggaca gggaggaggg
     6841 agaagaggaa tcggaaggag ccagggaaga agaccccagg ccaagataaa acccatggat
     6901 ggtactattg taattatccg taccgggagt gtaataatta aaaacggtcg ctgcctccga
     6961 ggaaacagca aagcttccca tcgcgattaa aaatgtcagt gttttcttca tatttattat
     7021 tccttttgga tggcaacttg tagcgaattt ggaattcccc aatcggattt ggaatccgtc
     7081 aagtaatgaa aaagaggcca aatcaatcat gaaaccaatg aataacaaag actgacccgt
     7141 catcttagca aaaggaccag agatattaaa aaatcattat tttcaatgaa ttataaatac
     7201 aatatactaa ctcttaatat ttttaattgc ttgcggattc caaattcgtt attcaagcac
     7261 aagtacatac attgaacctt gaatcatttt attaagatac tgaccatgaa taaattatta
     7321 tccaccctga ttctttcggc cggcatgagc ctaagcgcta ccgcggctac cgctctgttg
     7381 gatagctcca tcgtgggata ttcggacttt gcctcccaaa cggcggattt cggcacccgg
     7441 aaagattccg tttccatcac gtctgacgac agcaatctga cgttgtccgg gataaccttc
     7501 aacggatacg gtgccaacaa ccgcgacgtt atgtctgtga cgatggttct tgacctgtcc
     7561 aaaatcaaca ctccggagac ctataccgct ctgtttaacg ccaaaaacag cagtgtaagc
     7621 tggggcgtgg gcctgaacac ggaccggaaa ctccagggat tatggaacaa cacctcatac
     7681 agcgggcccg tcgttgacac cccgctgggc acggaaggtt ccctgaccat ttccgtagtc
     7741 accggagatc ttggcacccg catctatttt ggagacagcg ctacgtacta ttccaacagc
     7801 ggcctgaaat tcggcaacca gcaaattaat cagattctca tggacgcagg actggctgaa
     7861 tccatcgaac agctctacat ccacgactcc ctcctttccc aggaacaagt tggtcagctg
     7921 atgagtgaaa tcgccagcat tccagaaccc gccacggctt ccctgggcct gctgggactg
     7981 gccgcgctga tgatgcgccg ccgcagggca taagcctgta ccgtccgcct ccctatattc
     8041 aaaggccggc tcacaaaatc gtgagccggc cttttcctta tccgttcaaa catctgccgg
     8101 aaaaaacagg gggaagaagc ttctatttgc tgggtaccct cacggccagc acttgacggg
     8161 gaaatggcat tcaggctccc ccgggagggt catttcaaga gcttccggcc ccgccccact
     8221 tccgtacacg cccctttttc ccatgccggg acagccggaa ccggagcatg caaagcccgg
     8281 cttccctcag catccggaac agcccatcct ttcagcaatc catttccccg cacggtccgg
     8341 atcgctgcgg tttccgtccg tcggcaacag actccttccc tgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgaacttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gagtagaggg ccgtaccctc cgccgcgccg
     8701 cgggcggaat taacgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtagccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagtc ctatttcccc gatgccgagg acattgggcc ggtcgatgaa
     9241 ctccggaatc agcttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctactg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatca aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtacttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgttggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 tgcgatgggt tgcaacgtca ctgccgccta caaagcctac aagcgtggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaaaggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaagaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggtaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggttgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgttgcccg cttacctgac gaccaccaag cccggtgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa agcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaaa tggaagcgga aggcttcggc aactgcacga
    13381 accagtatga atgtgaagct gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcga gccaacgcca aggaaggtct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt tttttcatta
    13561 tcaggtttcc ttgaaccagg aataaaatac cagacagttg cttcctcatc gtcgcgcagc
    13621 gtaaaaaatt gttacaccgg aagggttcca gtaatccagg agaccgtact tggaaatgcc
    13681 ggacgaaacc taagcaggcc ccgtccgaca gcgacggccc catctttctc cgagaaagaa
    13741 aaacattgat tacaggaatt agactgatgc ccggaaggga tggcctcctg tcaagggctc
    13801 agcatgagag gaaaacattt tctaacaaac agacaacatt gatgtctatt aagggaatgc
    13861 actgaacgta agaattataa tattatcttt tcgtgtaaaa taatgaccat cttttataaa
    13921 aaatcaaaaa catacaaata aaattctatc gacaccgact tcagatcata ctattgataa
    13981 aacgatcagg aaagggcggc ccctcgcttc cttcattacc cccgactctt gaatacctga
    14041 tgaatccgcc tcatcgttcc tcctccgccc atcgttctgc cgttcccggc taccggaaat
    14101 ggtactttgg agccggcggc agccccggca ggcggggcat ggagg
//
