LOCUS       c00106_gnlPro..        15093 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDNLGFDJ_106.
ACCESSION   c00106_gnlPro..
VERSION     c00106_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:07:18
            Original ID  :: gnl|Prokka|GDNLGFDJ_106
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15093
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15093
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5637]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15093
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15093
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_1"
                     /sec_met_domain="IlvN (E-value: 4.3e-49, bitscore: 155.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.6e-10, bitscore: 31.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLR"
     CDS             complement(740..1471)
                     /locus_tag="ctg106_2"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(1508..2062)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_3"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-18, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(2075..3775)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(3802..5637)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.8e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             complement(5955..7502)
                     /locus_tag="ctg106_6"
                     /transl_table=11
                     /translation="MAALYPIGIQNFEKIRKEGYLYVDKTALIYQMVKTGSYYFLSRPR
                     RFGKSLLVSTLEAYFQGKEELFEGLAMEKLEQDRLEYPILHLDLNAERYSEASSLDSIL
                     QRHLNLWEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELL
                     QDEYRSILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICG
                     MTETEIHAYMEQGVLDLTRNLQMDYEEVCMELKRRYDGYHFTHRSQGMYNPFSLLNTFA
                     KSDFGDYWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSG
                     YLTIKSYNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDV
                     DAFLSRLQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTD
                     HYIYIMEFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             complement(7578..8174)
                     /locus_tag="ctg106_7"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             complement(8696..9904)
                     /locus_tag="ctg106_8"
                     /transl_table=11
                     /translation="MEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIYHYSEILNVD
                     ELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEWDILSSNEGI
                     FWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSLPWSDYLLEY
                     YENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQKYKYNWIWGY
                     SSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLIDKYLCKLHW
                     EECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREEDFRNNNGGII
                     NDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVLEKEKMKFLL
                     ELV"
     CDS             complement(10946..12466)
                     /locus_tag="ctg106_9"
                     /transl_table=11
                     /translation="MKGRSELLLIGPSYIRKIRMKKQFIYFLSLFVMCLAACSNPVDPT
                     ALNLDSANINRLIPFRGELNNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDYM
                     AEMIVSVNRMGDGEETELVLSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKIG
                     KPGKQDDFNVYLYSLEVTRPETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQS
                     GEPLAYEDAVNNFDVDRFARTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTKR
                     DLVADLSDALGKYGIRLILYYHVGHGDKEWWDKQHYTRDNAGDLFTNVEKIVGEISQRY
                     GNRLAGLWMDDGIGYYPNGASFEKIAKAAKSGNKELAICFNSWILPKLTDFQDYYAGEL
                     GLSLASAGVNDPSLPLDGDGLFHGGPQDGLQATFSGTLEPGDWTHIYKDSIIGDPVLSI
                     DELTQVVKESNKRKNLPMINVRIYQDGTISPKSYALLKELNNRISKGE"
     CDS             complement(12481..13923)
                     /locus_tag="ctg106_10"
                     /transl_table=11
                     /translation="MKRMKTLIKNILLAVPVILSASCSDWLEEDPKTFISPSSFYQTVE
                     DFDGALKGLYPQGQNLNLTEVFADYNDKPESAEQVGDIWANNPGYGFYAFRNAWSGPYS
                     TIKNANMILESIEDKDFTAETKNRIIGEAKCLRAWSYFTLVQFFGDVPLRDKVVTSDAD
                     VAIDRTPQADIYQFIFDDILDAEQKLPEEAQDMGRVNKWVVKAIMARIYLTSAGFPMNQ
                     KENYAKAKEKALEVINSGQYSLMPTFDKVFKTERYTAETIWAQLFSAPDSYSGMHNESS
                     PIGSQTALYLPTDAFIASFDKGDMRKEWGIKPEYVNAKGNKVIARTYYNKYINEEYLEQ
                     ELPASNTNILTWQTQLIRLAEMYLIAAEAENEINGPAGAYQYINAIRKRARVDQNDPTN
                     VPDLSGLSQDQFREAVLLERQHELYEEGFAWYDLKRTQTFDKVQKARGSRLNVPIGAYN
                     NTWLIPDTEILNNNIPQNPDYR"
     CDS             complement(13929..15092)
                     /locus_tag="ctg106_11"
                     /transl_table=11
                     /translation="IGQTGNQSISPYQTFARLGTSGPIFGDGKDIGFGLSSMANDDLKW
                     ETTTQTDIGVDFGFFSNRLNIGFDYYWKQTRDLLYNATLPPSSGYSSMLRNLGRIDNKG
                     FEISINTINMKGKVNWTTNLNITSNRSIVKDLGSDVYGNKIQRIDAPIGGGNWFPLFVG
                     KAPFQLYGYEIEGIYQTDEEARLNGEATKKAGDYRYKDTDGKAGITTGDKTIIANTQPK
                     FTFGLTNIINWNNFELSFLLIGSVGGDIVNEFNKSITNIGGTWNIRKDVWENHWTPENP
                     NAKYARASVATKDYLAFGDPSSVWVENGSYLRFKDIKLAYTLPSQWFAGSRKPNISVYL
                     SGQNLITITSYSHYDPEASWTSSAVNGWDRGVYPSAKSFTLGLQVKF"
ORIGIN
        1 tcacgcaaag tttcgtactg agccaacagt aatccctgga tagctcccat caaagtacca
       61 cgttcgccgg tcaggtcaga ataaacttct ttcttgaatg ttgtttcaaa caagtaacca
      121 gaaccaacac cgatacccag tgcaatcacg cgatcccatg ctttgcctgt tgcatcctgg
      181 aagattgcgt agcttgagtt cagaccacga ccctgcaaga acatacggcg cagtgaagta
      241 cctgaacctt tcggagcaac caggattacg tctacatcag caggagggat gatgtttgta
      301 cgttctttgt aagtgatacc gaatccgtga gagaaataca aagccttacc cggagtcagg
      361 tattttttga tgcgcggcca aacttcaatc tgagcagcat ctgaaagcag atactggatg
      421 atagttgctt tttcgcatgc ttcttcgata tcgaacagtg tttcgcccgg tacccaaccg
      481 tcagcaacgg ccttttccca ggtcttacca cctttacgtt gtcctacaat tacgttaaaa
      541 ccgttgtcgc gcaggttcag gctctggcca ggaccttgta cgccgtaacc tattacagcg
      601 attgtttcgt ctttcaatac ttctcttgcc ttttccaacg gaaattcttc gcgggttact
      661 acgttttcgt caacgccgcc aaaattcatt actgccattt tctttttact attaaaatgt
      721 atataaaata atttgttttt cagatccagg taacggcagc gcggctgatg gctttgccgt
      781 cgttacagat tgccatatta tatttatcga gggatacttc ctggttatgg agagtcagct
      841 ccatcccata ctttccttcg gactgataag ctatttcgaa acggcttatc tctttttctc
      901 ggaacagact gatatcgaac aagtcgagca ggtgttccat gtatttgata ctgttcaggt
      961 ggccgtttac gtccaggtca ctatacttca cacggtaagg ttcgccggaa gtgttgtttt
     1021 ccaccggagc aattttaccc ggtttttcaa tcggacaggg acggtcggtg atataagcac
     1081 tcaggccctc cacatcgagc aaggtcgggc ggcgggtttc catatcgata gccgcccaga
     1141 tagagcgggc aaagccaaag gtcttgcctt cgccgttcac cagttcaaag caacggctgg
     1201 taaacaactt accgacctca tccacccagg tatataaagt tacggattca gacatggcag
     1261 gataagaagt catctcgata gccagacggg aaagaaccca ggcggtatgc ctttcggtca
     1321 tatcgttata tccgaatcca cggtcggcgg catggcaaga agcagcatgc aacaaataag
     1381 ttccgatcat agggattgta atacgtcccc ggaagtccgt cagataagac tctgttacga
     1441 aatgaaattc tcctactttg ttcttctcca taatttactt tatttacaaa atgtttcctt
     1501 attattctca gacatgtttt tcctgcaact tcttttccat tgcagataac atgtcgctca
     1561 gacgttctac cttactcttc gttatagcaa cgcgtccgga acggataaat tgcaggacac
     1621 cgatcgtctc actcaattct ttaaacaaag cctgtgtctc atcataatga ccactctttt
     1681 ccaacaccac acaatcctca ttcatttcaa ggatacgggc attgtactta cggatcagat
     1741 cctcaaccgt ccccatcttg ataaagagtt cggtactcag tttataaaga gcgatttcct
     1801 ggtaaaccag gtcttcatcc gtattataat aggctttcag gatatccaca cgcttgtcga
     1861 tctgttttac gaccttgtcg atcgtatcct cgtcggcaaa ggtagtaatt gtaaacttat
     1921 gtattccctt tatagcagag ggagaaacag aaagcgtctc aatgttcagt tgccggcgcg
     1981 taaagataac agttatctga ttcagaagac caacagtgtt ttccgaaaag ataataacgg
     2041 tatataattg ttttgtattc atagtttctc ctccttactt atcacccaaa atcatgtttg
     2101 tcacgcttcc tccggccgga accatcggat ataccatacc acaagtttcc acattggcaa
     2161 ccaacatata ggcaccatcg tgattcaaca tttcagcaat cgcctcatcc aagtcttccc
     2221 gtttatctac cgcacgggaa gcaataccaa aagccttggc tatcgctaca aaatccggat
     2281 tcttcatgat ggtattcgaa taccgttcgt tgaagaacag ctcctgccac tggcgtacca
     2341 ttcccaggaa attgttgtta agaacgatga tctttacatt cagattttcc tgcatgatag
     2401 ttcccaactc ctggatagtc atctggatac caccgtcgcc ggtaaagaaa cagaccgtac
     2461 ggtcaggcgc tcccagcttc gctccaatgg cggcgggaag gccaaagccc atcgttccca
     2521 aacctcctga agtaactacg ctgcgtgttt gtttatattt gaaatagcga acacccatca
     2581 tctggttctg acctacatcc gtaaccagaa tcgcatcatt atcggttgct tcggaaacct
     2641 tacggactac ttcgcccatt ttcagttggc cttcggtagg atagagttct ttttctatta
     2701 ccttattata ttcctctttt tcatccggtt cgaattcagc attccattcc ggacgcttcc
     2761 gttcttccag taaagccgta atcatcggaa tcgtatgctt ggcatttccc agcactttca
     2821 cgtcgaccgg cacattcttt ccgatctccg aattgtcgat atccaggtgg ataatctttg
     2881 cctgcttggc ataagtcttc aggtcgccgg ttacgcgatc atcgaaacgc ataccgatag
     2941 caatcagcac gtcacattcg tttgtcttgc ggttcggtcc gacatttcca tgcatcccca
     3001 acataccttt atttaatggg aagtccgaag gtaatgcaga caagcccaat acggtagaac
     3061 cggctggtat atcgtttttc aacaagaatt ctttcagttc ttcttcagct cctcccagga
     3121 taaccccctg ccctaccaga cagaatggct ttttggcatt atttatcaat gaagcagccg
     3181 cctcgatacg ttcctccctg atatccggtt caggttggta actacgaaca taatccactt
     3241 tctgatactc ataatctacc aaacccacct gtgcatcttt cgccaaatcc agtaccacag
     3301 gtcccgggcg accggtcgat gcgatataga aagcacggga aacggcccaa gcaatttctt
     3361 ccgggcggcg tatctggtaa gcccatttgg taatcggttg tgtgataccg atcacatcaa
     3421 cttcctggaa agcatctgtt ccaagcagcg gagacggaac ctggccggca atcaccacca
     3481 tcggtgtact gtccatcagc gcatcggcaa taccagtgat ggtattggtt gccccgggac
     3541 ccgaagtaac caccgttact cccacttttc cggaaacacg ggcatatccc tgtgcagcat
     3601 gtgttgcacc ttgttcgtgg cgcaccagaa tatgttttaa ctgatctctg taatcgtata
     3661 aactatcgta aattggtatc gcctgcccac ccggataacc gaagatagta tctactcctt
     3721 cagcgatcag cgctttcagc aaagcttccg aaccggttat cttttgtttg tccatctcta
     3781 aaatatagta tttggtgttt attaatcttc tactattcgt acaccgccct tatcggccga
     3841 agcaaccatc tttgcatatg ctttcagtgc tttcgatacc gtacgttggc ggaaaggagg
     3901 tgtaaaggct tttgttccgc gggcttcttc cgcttcacgg cgtttggcca gttcttcgtc
     3961 tgtcaccttt acatgtatgg ttctttcggg aatattaatt tcgataatat cgccgtcttt
     4021 cactaagcca atcgctccgc ctgcagccgc ttcgggagaa atatgtccga ttgacaaacc
     4081 cgatgttcca ccgctgaagc gtccgtctgt gattaacgca cattctttac ccagatgttt
     4141 actctttata taagaggtag gatacaacat ttcctgcata cccggaccac ccttaggacc
     4201 ttcataggtg ataacgacga catcgccgga gacgacttga tctttcagga taccttcgca
     4261 agcggcatcc tgcgaatcga atactttggc agggccggca aaacggaaga tactttcatc
     4321 taccccggct gttttaacca cacaaccgtc ctgtgcaata tttccataca gaacagccag
     4381 accgccgtct ttcacataag catgttccac atcgcggata catccggttg cacggtcggt
     4441 atccagttct ttataataac tttcctgcga tccgagcacc agattgaaac ggtgggccgg
     4501 agcactttta taaatattga ttgcttcttc cgttacattt acagaggtaa tgcagtattg
     4561 gtcgatagcc tcattcaaag tcagaccatc cgcacgtttc acggaaccgt ccaccagacc
     4621 ggcttttacc agctcattca taataccgat aatacctccg gcacggttca catcttccac
     4681 atgataagaa caactcggag ccactttaca gataaccggt gttttgcgtg aaagcatatc
     4741 gatgtctttc attgtaaaat cgacttccgc ttcatgagcc acggccaaca ggtgaaggac
     4801 tgtattcgtc gatcccccca tggcaatatc cagcgacata gcattcagaa aggcctgacg
     4861 ggtggcaata ctgcgaggca atacggaatc atcgccgtca cgataatatt taaaggcatt
     4921 atcaacaatc atcttcgcgg cttttttgaa caggcgggta cggttggcat gtgttgcaac
     4981 aactgttccg ttgccgggaa gagccaatcc aatcgcttcg ttcagacagt tcatagagtt
     5041 agccgtgaac ataccagaac agcaaccgca ggtcgggcaa gcggaacgtt ccaccttttc
     5101 tacttgttca tcgctgatag aatcgtcagc cgcttcaatc atggcgtcga tcaaatcgag
     5161 tgcacgtccg tccagattac cggcttccat cggaccgccg gatacaaaga ttgtcggaat
     5221 attcagacgc atactggcca tcagcatacc cggagtaatc ttgtcgcagt tactgataca
     5281 aaccattgca tcagccttat gcgcattcac catatattcc acactgtcag caatgatgtc
     5341 gcgggaaggc agagaataaa gcattccgtc gtgtcccata gcaataccgt catcaatagc
     5401 gatcgtatta aattctgcgg caaagcaacc gagcttttcg atttccgctt ttacctgctg
     5461 tccgatctcg tgtagatgca catggcccgg tacaaactgg gtaaatgaat tcacaatggc
     5521 aatgatcggt ttaccgaact gttcttcttt catgccgttg gcacgccata atgcacgggc
     5581 tccggccata cgtctgcctt ctgtgctata ggagcttctt aacggattct tcatcatatc
     5641 tgtttttatc ttttagtcaa taaaaaagcc cttctctata tggagaaagg cttaagaaat
     5701 atcttttacg acttcacaac ttcttacaca cctttctcct tacctactaa tgactagaag
     5761 gaccaccacg agaataatat gtaatacatt gttcatcatc ttttcttatc gtctttattt
     5821 tgtttgacgc tgcaaatgta gaataataat ttgtacgagc aaaggattta aaagaaaaat
     5881 cttacttttt ctttcattta tcaataaaag agggcggttc atcttgcatt ttaacagtat
     5941 tattaaaatc tacatcaatc gaccgaccaa ccggctatgt tccgtgtttc attatcaaag
     6001 ttcaccccta tcttaaaaag tttccgttca tccgaggcaa aaggcaaggc atactgcttc
     6061 tcttcgatct gcctcatcgc ctcctctgtc gtgccatcca acttaaactc cattatataa
     6121 atgtaatgat cggtttgcaa caccaggtca atgcgaccac gggaagtacg atattccacc
     6181 ttcacataga aaccgaccag tttgaagacg atgaacagga cgttctggta gtgcacttcc
     6241 agatttcgaa tcaattcata tggcgtatcg gcaaaaaaac tttgcaaccg gctaaggaaa
     6301 gcatccacat ccccagactc gatttcttta atgaatttaa aaagctggaa ggaagtatca
     6361 ataacattga cagaagtgta atatggaagc aaataattca gaaacccctc ttctacttcc
     6421 tgatttggaa agcccaatgt atatatttta aatctaggat tataggattt gatcgtcaaa
     6481 taaccacttt ggtaaataac cggtatcggg ttacgcgaaa cggcatcgat actgttcaac
     6541 acatctgcat tcgtttccgt atgtgccata ttgtacaagt catagtcggt atgcttcaac
     6601 agctcgacca agtaagaggg ggtacctgtc tcaaaccagt aatctccaaa gtcagacttc
     6661 gcaaatgtgt ttaacaaact gaacggattg tacatgcctt gcgacctatg agtaaaatga
     6721 taaccatcat aacggcgttt caattccatg caaacttctt cataatccat ttgcagatta
     6781 cgagtcaaat ccaacacccc ttgttccata tacgcatgga tttccgtctc ggtcatacca
     6841 caaatctcaa cataacgatc atccatcgaa atatccatca aattgttcaa atcactgaac
     6901 acacttactt taccgaactt tgtcacacct gtcagcaaag caaaacggat atcaccgtcc
     6961 atcgtcttca acaccccata aaacggtttt aatatagaac ggtattcatc ctgcaacagc
     7021 tcatccccaa tagcctgcaa caaaggtttg tcgtattcat ccaccaaaat gaccacacgc
     7081 cttcccgatc gagcttttgc ccggcggatc acccctataa aacgatcgga caaagtcttt
     7141 tcccgttcat cttttcccca tgtatcttcc cacaggttca aatgacgttg caaaatacta
     7201 tccaaggacg aagcctccga atacctctcc gcatttaaat ccaaatgcaa tatcggatac
     7261 tccaacctat cctgttccag cttctccatc gccaatccct cgaacaactc ctccttaccc
     7321 tgaaaatagg cctccaaagt cgaaaccaac aacgatttgc cgaaacggcg cggacgactc
     7381 aggaagtaat aactcccggt cttcaccatt tgataaatca acgctgtttt atcaacatag
     7441 agatacccct ccttacgaat cttctcgaaa ttttgtatgc caataggata aagtgcagcc
     7501 ataaaccgtt tttatattat ctatcaagac aaaggtaact tattttttat caataagtat
     7561 cttattatat tacattttca tcggatttcc ggaatcttga ccttctcccc ccaaaaacgg
     7621 ggttgcttac caataatcaa gtctataaat attttaaccc gagccaaaag ctcacgacta
     7681 tgtcccctca accaggttgt ccacacagaa gtcacatctt gggcattgaa tgcaatcgca
     7741 tctatttgat tatgacccgc caaatagatc gcacgctcgt tatgaaaaga ctgcgaaata
     7801 acagtaacgc tatcctgtcc aaaaatggct ttacatcgca cttccaaatc aagcgttcga
     7861 aaaccgacat aatccgaaat aattcgctca tccggtacac cacaggcaac taacgaatca
     7921 cgcatacaag tcggctcatc ataatctgtt gaatgattat caccacttac aataaagtaa
     7981 tcaacctttt ttgcatgaaa caatttgact gccgcatcaa tacgatacgt aaaataaaga
     8041 tttttcgttc cccaaggagt aaccggagca gtccccaaca acaaaccgac tttacgatgt
     8101 ggtatctttt ccaccctgtc aaatacctta cctgaggcac aacctgccac caacacgtta
     8161 caaactacaa ccactatgtt tatgacagaa atgagcagaa ataatggtta attgtatgat
     8221 tttcttctta ctttgaatta ccttttttca cagacttgct cttttattat aaaggattgt
     8281 caccaacaaa ataacaatcc taataaaaca atctatttct tcttaggaat atttttgtaa
     8341 aaggcatata gcaaaggtat tatttccaga catatccaaa gccataagca tgtcatattt
     8401 catttgacag gaaagcttcc gtcttcacca atcattaccg gataaaacat atcatccctg
     8461 caaagaacga ttgctccaac ctatcagagt aatataaatt ttgcagactg tattaactaa
     8521 taatattttc actgtcccca aaatacgatg tcatattttt caacacacga tctttacttg
     8581 tattagcata gcaatagact tttctataaa atataggcgc atattctttt cttcagcttc
     8641 gtcacttata taactatcct acccaatcat ccacgaccat tttttgatac ttcaatcaaa
     8701 ctaattcaag taaaaatttc atcttttctt tttctaaaac acttaaacag ttatcgtata
     8761 ctttcacatt tcctttcatt agattccaat caaaccaaca tctattatca tatagtactc
     8821 ctacagacca aggtaaacct tcattcatac tcaataattt ccagtaagat ttatcacaat
     8881 catttattat tccaccatta ttatttctaa aatcctcttc acgccaaggg aaagacatat
     8941 tagaacaaat ttcttttata tttaaataag gtttatattt atccacaaag tccaagctcc
     9001 aaggcaatga aggattacta ctgagacctc ccatacccaa aggaggacac cagcattctt
     9061 cccaatgcaa tttacataaa tatttatcaa tcaaacattc attccacata tctcctgtat
     9121 ttaaactaag ctctccccaa tcaataaaac catcaaacat ctctatcaat tcctcattcc
     9181 agtgaatacc cgaattgcca cataaaccta tatcatcggt cattacccaa tctgatgaat
     9241 atccccagat ccagttatat ttatactttt gtataaactc agaactccaa ggtaacgctg
     9301 gattcatact taatccagcc caatttaaac gatccatata tttaatgatt aaatcatcag
     9361 tccaaggcaa cgatggattg gcacttatca agttccaatc ccataaattc tcataatatt
     9421 ccaacaaata gtcagaccaa ggcaatgaca gattagcact taaattaacc caatttaatc
     9481 tatcaacata gcgatttata aaatcaattg accacggtaa cgatttattt aagctcaaca
     9541 aattccaatt taacttagat ttatacttat taagcagcaa ctcattccag aatattccct
     9601 cattagaaga caagatatcc cattcccaat aatcataata tttatcaaaa agatctgctg
     9661 tccatgacaa acacttattt ccactcaaat attcccaatt aattttttct ttaccccaaa
     9721 attctatcag atacatatcc caatttaaag cttcatttct acacaattca tcaacattca
     9781 aaatttcact ataatgatat atatcatatt tttcaaaacc ataaaatcta cttaatacat
     9841 caataaaaaa atttctatat tcaatatata atacagttaa tttcatatca tccaactttt
     9901 ccataataat tagagcctgt ttaaatttca cagtttgaaa taaataaagt gtttcctctt
     9961 tctgctaaaa taattatttt taattactaa gtttcaaata attatgtatt gtacggattt
    10021 agaagaaaca cagtggcaag ttatcaagaa aatcttgaac ttgcaagaaa gaaagcgaaa
    10081 atacagggca accgcaccaa aatagttctc gcccgaaaga aaacggatgg ggaaatgttc
    10141 tttttttgat aagtgccatt tttgccaaca caaaacaccg ttttacataa ttgaaatggt
    10201 agtttaaaat caatgagaaa gtccgcgacg gaaacaatct tccccctcca tggttttcat
    10261 acctctgcct tcacactcgt aacacactgt attatatcct tttgtggtga aaccagcctt
    10321 ttcactattg tttttggaac cgtaacagga acccttccga tgagtaggca tctgtgggga
    10381 aatagatagt tatctatgtg gacacggata gttatccgtt ggggaagaac cactcgtctt
    10441 cacacagtca tgtgagtagt gctgacacta cgatgccggc cggatgggat agcagtaccg
    10501 gtatgacggt acacctaccc tataacgtac ataccaatag ggtatagggt accggacgct
    10561 actttacagg gtataatctg ccggactata ggggaaaatc gtacgtattc ttgggaaaag
    10621 acgtacgctt ttgttcgaac aatattttat ctcccttcac agcaaacaac tgtcctataa
    10681 tatgttacaa acactgaaag atgaaatcaa atttataaaa ctccattggg agattgattt
    10741 tttcccctaa aaacgagaag gtgtgtcaaa acactattac cgaacgcaga cggagcgcag
    10801 acaataatta ttttttaata aaagtttgtg cctgtctgcg tgttctgagt cgttagcgtt
    10861 cagtaattac tattttgaca catcacccaa tcaattgaat tcttatttct gagcctccat
    10921 tcgcttcata ttcgataatt tccggtcatt ctcctttact gatacgattg ttcagttctt
    10981 tcaacaaagc atacgatttc ggagaaatcg ttccatcctg ataaatccgg acattaatca
    11041 tcggaagatt ttttcgtttg ttagattctt tcactacctg cgtcaattcg tcaatggaaa
    11101 gaacaggatc accgataatg gaatctttat aaatgtgcgt ccagtcaccc ggctccaatg
    11161 ttccggagaa agttgcctgt aagccatcct gagggccacc gtgaaacaat ccgtccccat
    11221 ccaacggaag agaaggatcg ttaacaccgg cactggccaa agacaaaccc agttcgccag
    11281 cataataatc ctgaaagtcc gtcagtttcg gcaatatcca ggaattaaaa caaatcgcca
    11341 actccttatt tccacttttg gcggctttag caatcttttc aaacgaagcg ccgttaggat
    11401 aataaccgat accgtcatcc atccacaaac cggccagacg atttccatac cgctggctaa
    11461 tctctcccac tatcttttcc acatttgtaa acaaatctcc tgcattatca cgtgtataat
    11521 gctgcttgtc ccaccattct ttatctccat gaccgacatg gtaatacaga atcagacgaa
    11581 tgccgtattt acccaacgca tcagataaat cagccactaa atctctcttt gtggtacgcc
    11641 ccggcaaaat agaatcgatt gcctgtatcg gagccgggaa ataatattcc gcccacgacg
    11701 ttgtaaaaaa tatcaacttc ccgccacatt cgtaaacagt tcgtgcaaag cggtccacat
    11761 caaagttatt gaccgcatcc tcataggcta acggctctcc tgactgaggc atactctttg
    11821 aattccagtg gaagaaaaag ccataaggca aatccgccat ccaggatgta ttactgcgaa
    11881 gtgatgtagc ttccgcccgc agctgctcat aagtctccgg ccgggtgact tccaacgagt
    11941 acagatacac attaaaatca tcctgcttac cgggtttgcc aatctttaaa gataaaacgg
    12001 aagtcccctt attaaaatgt aaaggacggg ggaaccggca acgctgccat ccggttgtat
    12061 ttatccggca aataacactg tccgttccat tggataatac caactccgtt tcttccccat
    12121 ctcccatccg gttgacagaa acgatcattt cagccatgta gtcttcaccg tccgtattga
    12181 ctttccagga tattgactgc tcgggagttt tccagttctc cgcccagaat gctttataag
    12241 gttcttccgg ataaagttgt ttcacaccat tattcagttc tccacgaaaa ggaatcaacc
    12301 ggtttatgtt cgccgaatcc aggtttaatg ccgtcggatc aaccggatta ctgcaagcgg
    12361 ccagacacat aacaaacaaa gacaaaaaat aaataaattg ctttttcatt cgtattttac
    12421 ggatatagga agggccaatc aataataact cagaccggcc cttcatgtat tctacattaa
    12481 ttatctgtaa tccggattct gaggtatgtt gttattcaga atttcggtat caggaatcaa
    12541 ccaagtattg ttgtaagcac cgatggggac attcaatctg ctgccacgcg ctttctgtac
    12601 cttatcgaat gtctgggtac gtttcaaatc gtaccaggca aaaccctctt catacaattc
    12661 atgctgacgt tccagcagaa cggcttcacg gaactggtcc tgagaaagtc cgctcaagtc
    12721 aggcacgttt gtcgggtcgt tctggtcgac acgggcacgt ttacggatag cattgatata
    12781 ttgataagca ccggccggtc cgtttatctc attttcagct tcggcggcaa tcagatacat
    12841 ttcagccaaa cgaatcaatt gagtctgcca ggtcaaaata ttggtattag atgctggcaa
    12901 ctcctgttcc agatactctt cattgatata cttattataa tatgtacgcg cgatgacttt
    12961 atttcctttc gcatttacat attcaggttt aattccccat tctttacgca tatcaccttt
    13021 atcgaagctg gcgataaaag catctgtcgg aagatacaag gctgtctggc tgccaatcgg
    13081 tgaagattca ttatgcatac cgctatagct atcgggagcg gaaaacaact gagcccagat
    13141 agtttcagcc gtataacgtt ccgtcttaaa gactttatcg aaggtaggca tcaaagaata
    13201 ctgaccgctg ttgattactt caagcgcttt ctctttggct ttcgcataat tttctttctg
    13261 attcatcggg aagccggctg atgtcagata gatacgtgcc ataatcgctt ttacgaccca
    13321 tttatttaca cgtcccatat cctgcgcttc ttccggaagt ttttgttccg catccagaat
    13381 atcgtcaaaa ataaactgat agatatcagc ctgcggcgta cggtctattg ccacgtcggc
    13441 atcactggtc acgactttat cccgcaaagg gacatctcca aagaactgga ccaatgtaaa
    13501 ataagaccag gcacgcaaac atttcgcctc accgataata cgattcttgg tttcggcagt
    13561 aaaatcctta tcttctatcg actccaatat catattcgca ttctttatcg tactgtatgg
    13621 gccggaccag gcatttctaa aggcataaaa accatatccc ggattatttg cccagatatc
    13681 cccgacctgt tcagccgatt caggcttatc attatagtcg gcaaaaactt ccgtcagatt
    13741 cagattttgt ccctgaggat ataacccttt caaagctccg tcaaaatctt ccaccgtttg
    13801 atagaaggaa gagggagaaa taaatgtttt cgggtcttct tccagccaat cggagcaaga
    13861 agcagacaga ataaccggta cagccagcaa tatattttta atcagtgttt tcattctttt
    13921 catacgtatt aaaatttaac ctgtaaaccc aaagtaaatg atttcgcaga cgggtaaacc
    13981 cctctgtccc atccgttcac ggcagaagac gtccaggatg cttccgggtc ataatgagaa
    14041 tagcttgtaa tcgtaatcag attctgtccg ctcagataaa ccgagatatt aggtttacgg
    14101 gaacccgcga accattgaga cggcaacgta taagccagtt tgatatcttt gaatcgcaga
    14161 tacgaaccgt tttccaccca aaccgaactc gggtcaccga aggccagata atccttggtc
    14221 gcaacagaag cacgtgcata tttggcattc ggattttcag gagtccaatg gttttcccag
    14281 acatctttgc ggatattcca tgtgccaccg atattagtga tacttttatt aaattcatta
    14341 acgatatcac caccaacact acctattaac aggaatgata actcgaagtt attccaattg
    14401 ataatattcg tcagaccgaa agtaaactta ggctgcgtat ttgcaataat cgttttatca
    14461 cctgttgtaa taccagcttt cccgtccgtg tctttatacc ggtaatcacc tgctttcttg
    14521 gttgcttcgc cattcaaacg agcttcttca tccgtctgat aaataccttc tatttcgtag
    14581 ccatacaatt ggaacggagc tttaccgaca aacagaggga accagtttcc gccaccgata
    14641 ggagcatcta tccgctgaat cttatttcca tacacatccg aacccaaatc tttcacgatt
    14701 gatctattgg atgtaatatt caaattagtc gtccagttca cttttccttt catattgatt
    14761 gtattgatag atatttcaaa acctttatta tcaatacgtc ctaagtttct cagcatagaa
    14821 gaatatccgg aagacggggg aagagtcgca ttatacagca aatcgcgcgt ttgtttccaa
    14881 taatagtcaa aaccgatatt caggcggttg gaaaagaatc cgaagtcgac acctatatcc
    14941 gtttgtgtag ttgtttccca tttcaagtcg tcgtttgcca tggaggataa accgaaacca
    15001 atatcttttc catcaccgaa aataggaccg gaagttccca gacgggcgaa agtctgatac
    15061 gggctaatag attgattacc ggtctgtccg ata
//
