LOCUS       c00010_gnlPro..        18511 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKBKLHLK_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:53:56
            Original ID  :: gnl|Prokka|JKBKLHLK_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18511
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18511
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5447:8511]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5448..8511
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..18511
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..18511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             136..1488
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="MTLRKKTLWFLGALSFFASLAAAFAVFWLNRNDSSPAEWNFNPIW
                     TKAEKEQILTAANFTAHRSPERFIYRGLSLNSRHIDWHMFSEVSMRQYMKDEIRERLQM
                     IRDTAESADGRCITPSHETLLHLAAGLGEVQLLNRLLQRHADPNVQIILPQQAFPSIPD
                     SEQGNTPLTYACQPGMDDSTPLPVHNRLSCLNLLIQYGADVNKPGPLGWPPLIITCVAG
                     IGGAPYEEAALFLLKCGADISLQPELKGKKTSLLTWAAAAGYPLLVRKLCEAGYDPNFR
                     GEMAPPLLSLNLNTPNAALQIAHILLEYGADVNAAMPASTTLPETAGDTALLNLCRQLA
                     FIDVSCLPQIRDLVNLFIKEGADVNHQNAAGETPLMACCRGMLLGDDSLDRLKLGIARL
                     LLDHHANPSLKDKYGRTALQRIGNRSNEHLQMVLKYLPELSAPPLPKKENH"
     CDS             complement(1502..3289)
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MKNLLFALLTGSFCCCYAQQKAAPVPEPEVVATPPADAGRGLIRV
                     DSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTREF
                     IRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKG
                     RRVIVPFHNMGGGTKFHISDDGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVL
                     EMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGTLTMNTLGRLDDGTIVSLW
                     TNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATL
                     DGPEDRGKHQSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQW
                     TIHTYIPQKKGHCSYNRKPSAELVQDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGA
                     TWNFPNGTTGLVKFRFRVVDGEQADDSGLQVSLTDRLFNACDSTTKDYALFTFPIRLKP
                     APHLLLGMKKVPFTPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGASYIHFIS
                     TGSQPDAGILLDTVNARVK"
     CDS             complement(3374..4162)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 4.6e-23, bitscore:
                     74.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSYILAILLGSSSLAFSAPSIPASALPATLKPEPHQRDPYDW
                     NARHEAVKKRNRAVKPEYVMIGDSITHHWGGEPSGDGKNTGSGSWEKLFGPHAATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAELHNGKDIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             complement(4185..4340)
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MDEMERALEEAGHGARLAVVAAGFAGRAVVFFTLPEEVTPAILMH
                     GRICLN"
     CDS             complement(4385..5167)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_5"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2.4e-23, bitscore:
                     75.6, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYACLCLLLAGVFCVACFSGACADELPPTLKPQVNPRAVYDWK
                     KRHEAVMERNRTVKPEYVVFGDSITHRWGGEPSGDNRALGTGKTAWHSLFSSHAVTNMG
                     FGSDYVDNAYYRLQLGELDGISPRVIIVLLGTNNLGGRKDAPRACADNLKAFVSLARRK
                     CPSSKILLLGILPREEKKLAPLIRETNKMISGLADGNSVFFANPGEEFLGEDGVSPKPG
                     LLEDGLHPSARGYDILGKSLSVLLKKMDDKYGKLPAPR"
     CDS             5448..7715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_6"
                     /sec_met_domain="Gly_radical (E-value: 8e-45, bitscore:
                     144.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.4e-281, bitscore:
                     926.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISIVKDLKESTALPQEWQGFKPGAWTESIDVRDFIQHNYTPYSG
                     NEEFLSGPSQRTLRLWDELKVLLKREIDNGGVLDADEEVVSSITSHKPGYIDKELEVVV
                     GLQTDAPLKRALMPFGGLRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDI
                     RAARSAGIITGLPDAYGRGRIIGDYRRVALYGTDKLIAERRKDLKNREHSPLTDELIRL
                     REEMSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGR
                     VSTFFDIYFTRDLEQGLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTES
                     IGGMGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPEAFKSFCAKVSIETSS
                     VQYENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGK
                     QVAPPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHD
                     PEILRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVD
                     DIACSLVSNFMEKLRRLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGA
                     NPMHGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAY
                     FAATGHHINVNVLERKTLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFH
                     TR"
     CDS             7732..8511
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 53.7;
                     E-value: 9e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_7"
                     /sec_met_domain="Radical_SAM (E-value: 9.6e-31, bitscore:
                     99.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQVFPQNHDPDGESSVTGLVHSVESCGTVDGPGIRFVLFLSGCS
                     LRCRYCHNPDTSYVRRGRLRSADDVLKEIARYRDFLQAAGGGVTLSGGDPLFQPDFAGA
                     VLKGCRKLGLHTCLDTSGHLGVNAGEEMLADTDLVLLDIKAWNPKRYRALTGGELHPTL
                     EFAERLASLRKPVWLRYVLVPGVTDNLEEIEELSRHAALLGNVERVDVLPFHQLGRFKW
                     DELKLDYTLKDVPEASAELAEQVRGIFRRGGFPDCVH"
     CDS             complement(8759..10684)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     RAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSRSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEAL
                     ATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALAADEFYN
                     DGPLDLGVMLDGDMETLKALEPYGPMMFSGLDMHPGARKYKFRVKAPVLRAAPPAHRVQ
                     LYLQLGGLHGLDVATPSLFPVKKAAPAEDAPILIAPFSRLGSASEWSREQWRELVSLLP
                     GRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDVAAAAVAVDGDFPSLCSFRG
                     LPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVREVLEALR
                     EISGKE"
     CDS             10999..11136
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MKRRHADCQIVKRKGTLYVICKSNPKFKARQGATAGTRLSKKGVK
                     "
     CDS             11223..12386
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_10"
                     /sec_met_domain="Abhydrolase_1 (E-value: 2.1e-27, bitscore:
                     88.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPAVQTKFLDLPNSFSLRNGATLDKVRVAYEQYGTLTPNKDNA
                     ILLFHALSGSQHAYGYNPEVPGIGSLWKPENHEGWWNSIIGPGKPLDTNCFCIICANYL
                     GGCYGTTGPATACPADGQPYGSRFPHVEAADQARLQALLLDSLGIERVHLMGPSVGGLI
                     ALSFACQFPERVRSFISIGSGYRASIEHRLSLFEQILAIELDPDFQGGDYYRGPAPKKG
                     LAFARIIGHKSFVYQEGLEQRARKEVGGNYGLLTWMAPTRSTQSYMLHQGTKFAERFDA
                     NAYIRIADMWAEFDIRDHTPDGTFQTALEGFRRAGIPALIFSIDTDCCFRPAEQQDFAA
                     QLEAAHIPTEFHTIASTKGHDSFLLEPELYAEPIRRILAAREPKGTA"
     CDS             12585..12995
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MTDHYYTSETENVGQFRCETTFIPSNVTFATDLPASFEGRAEFPS
                     PGVLLGSTLASCMMSLVSVVAARKGVDLKGMRVLARAAESSKGIEKIELKAIMPLEGSH
                     PLRAMLEKTALSCPVRQALRPDLETPIEWEWK"
ORIGIN
        1 tccgaatttg caatccgcca cccgaattcc cacatggttt gccccgggca ttctttgctc
       61 atactatttt ttcattgccc ggagttatgg attcctgcat catggccttt cgcagtaccc
      121 ctgcttatga tacacatgac tttaagaaag aaaactctct ggtttcttgg agctttgagc
      181 ttttttgcct ctcttgccgc ggctttcgct gttttctggc tgaacaggaa tgattcttct
      241 cccgcagaat ggaatttcaa ccctatctgg acaaaagcgg aaaaagaaca aattcttacc
      301 gcagcgaatt tcacagccca tcgaagcccg gaacgtttca tttaccgcgg gctttccctc
      361 aattcacgcc atattgactg gcacatgttt tccgaggttt ccatgcgcca atatatgaag
      421 gacgaaatca gggaacggct tcagatgata cgggacacgg cggaaagcgc agacggacgc
      481 tgcatcactc catcccatga aaccctgctg catctcgccg ccgggctcgg agaagtgcag
      541 ttgctgaacc gccttttaca gcgccatgcg gacccgaacg tccagatcat cctgccgcaa
      601 caggcctttc cctccattcc ggactccgaa cagggaaata cccccctgac ttacgcctgc
      661 cagccaggca tggacgactc cacgcccctg ccggtgcata acaggctctc ctgccttaat
      721 ctcctgattc agtacggtgc ggatgtgaat aaaccggggc cgctgggctg gccgcccctc
      781 atcatcacct gtgtagccgg tattggagga gcaccctatg aggaagcggc cctgtttctt
      841 ctgaaatgcg gtgcggatat ttccctccag cctgaattga aaggtaaaaa aacaagtctg
      901 ctcacctggg ccgcggccgc cggatacccc ctgctggtcc gcaagctttg cgaagccggg
      961 tacgatccca atttccgcgg ggaaatggcc ccgccccttc tttccctgaa cctgaacact
     1021 ccgaacgccg cactgcaaat tgcacatatt ctgctggaat acggagcgga cgtgaatgcg
     1081 gccatgcccg cgtccaccac cctaccggaa accgcgggag acacggccct gctgaacctg
     1141 tgccgccagc tggctttcat tgatgtgtcc tgcctccctc aaatcaggga cctggtcaat
     1201 ctcttcatca aagagggagc tgacgtcaac catcaaaacg ccgccggaga aactcccctc
     1261 atggcatgct gccgaggcat gctgctggga gacgattccc tggaccggct gaaactgggt
     1321 attgcgcgtc ttctgctgga ccaccacgca aacccatccc tgaaagacaa atacggacgc
     1381 acagccctcc agaggatagg caaccggtca aacgaacatc tccagatggt gctgaaatac
     1441 ctgccggaat taagcgctcc gccgcttccg aagaaggaaa accattgaat cccgccgctc
     1501 cttacttcac ccgggcattc accgtatcca gcagaatgcc ggcatccggt tgggacccgg
     1561 tgctgatgaa atggatataa ctggctccat tgggggactt attagccatt ttcaacgttc
     1621 cggccttctt tccgtccaga gacaccacgg cctgcccacc ctgccaaaga agggaaattt
     1681 catgccacgc gccgggcgtg aaaggcactt ttttcatccc cagcaacaga tggggcgcag
     1741 gtttcagcct gatcgggaag gtaaacaggg cataatcctt cgtagtggaa tcacaggcat
     1801 taaacagccg gtccgtcaga gagacctgaa ggccggaatc atccgcctgc tccccgtcca
     1861 ctacacggaa gcggaatttg accagccccg tggtcccgtt cggaaagttc caggtagctc
     1921 cgccgttccg gtaatccaca ttggattttt cattgaccag ttcgggatca tccagacgct
     1981 tgatttgcaa caccttcttc gtgcccccgg acggatcctg aaccagctcg gcggaaggct
     2041 tgcggttata actgcaatgg ccttttttct gggggatata agtgtgaatg gtccactggg
     2101 aatccaaatc tttccccgtc tgcgtggcac gcgtcttggc ccctacccag cggcggtcca
     2161 caataaccag gcggcggtgg tttttatgct gccccaggga aataaggatg cggtttttgt
     2221 ccagctgcac catttcgctc tgatgtttgc cgcggtcttc cggaccatcc agcgtagcat
     2281 agccgggatg gttgcggtgt tcgtccagga taatctcccg gaacccgtac caggttttgc
     2341 cctcgtcccc ggacatagca atgtggtggg aatcacggtt ggtgaataca tcctcccacg
     2401 ttccgttgcc agctgtggcg ttttcaggca gagccattgt attcgtccac agggaaacga
     2461 tagttccgtc atccaggcgt cccaacgtgt tcatggtcag ggtgccgaaa aagcgggaag
     2521 gctccggttt gctccacgtt tccccgtaat ccttggaaaa agcctgccac gcctggtcct
     2581 gggaggtgcg ggcaagcgcc cacaacgtac cgtctttcat ttccaaaacc gtggcttcca
     2641 cggcattgtt gaaccatctg acgccctggt gggggggcct ggcttcatgt ctgggggaag
     2701 taacaccgtt cctggataca tgccaggtca gccccccgtc atcggaaata tggaacttgg
     2761 tgccgccgcc catgttgtgg aacggcacga tcaccctgcg gcccttgttc acaaaaacgg
     2821 gggtccgcat gatgccgccc agttttttca ggtttttcct cttttccggg tctttccagt
     2881 cttcttccag tttgccgtca ttcgtgacgg caagccactt gccgtccagc ccacccctgg
     2941 aaagaaatac aaagcccccg ataggctgca cacgaatgaa ttccctggtc agagggttgc
     3001 gcacaatagc cggagattct ttgggaatgc caccgtagtt gggagggtag ccagccggag
     3061 cggccttcat ttcccatgtt tttccgttat ccctgctgac caggtaatcc ggttccttgc
     3121 gggtaccgga ataatggcgt atttcacggg agtccacacg gataaggccg cgccccgcat
     3181 cagccggcgg agtggcgaca acttcaggtt ccggaacggg tgcggccttc tgttgggcat
     3241 aacagcaaca aaaggaaccg gtcaacaatg caaacaacag gtttttcata aactaaatat
     3301 caaaggccgt atattttcct caaccggggc tttcccttca aacaaaatcc taccttccat
     3361 cagaagacga tcatcaggaa tgctttcccg cctgcttccc tccccggtat tttgcatcaa
     3421 gctttttcag gagtacggcc agttcctttt ccaaaacctc gtaccccctg gcattgggat
     3481 gcaccacatc cttcatgaat tcattctgcg gagaagcacc atctgcggaa agaagcgcct
     3541 ttcccggatc ggcaaagaaa atgtcctttc cgttatgcag ttccgccaac agtctgttcg
     3601 tctgcttcac cggttccgcc aggtttttct ccttccgtgg gagaacgccc agcaacagga
     3661 ttttggaaga ggggcacttc cggcgcacta ggcggacaaa tgccctgata ttgtccgcac
     3721 atgcctgcgg cgtatccttg cggtgcccca gattattggt ccccagcaac acaatgatga
     3781 cccgcggaga aatgccgtcc agctccccgt tttggacacg gtaataggca ttatccacat
     3841 aatcaaatcc aaagcccata ttcgtcgctg catgcggacc gaataatttc tcccaggacc
     3901 ccgatcccgt attttttccg tccccggaag gctcccctcc ccaatggtgg gtaatgctgt
     3961 cccctatcat cacgtattca ggcttgacgg cccggtttct ttttttaacg gcttcatgcc
     4021 gggcattcca atcatacggg tcccgctgat ggggctccgg cttcagggta gcgggcaacg
     4081 cggaggccgg aatggaaggc gcagaaaatg ccagactgga actccccagc aatatggcga
     4141 gtatgtagga gaggaaattc ataatcaaaa agtaaaaccg gttttcagtt taagcaaatt
     4201 ctgccgtgca tcaagatcgc aggcgtcact tcctccggca gagtaaaaaa gaccactgcc
     4261 cgtccggcaa atcctgccgc aaccacggcc aggcgagcac cgtgtccggc ctcttccaag
     4321 gcgcgctcca tttcatccat cccccggcct ctcccggaac aggaacgccc tcccccgtat
     4381 tcatctaccg gggagcgggc agcttgccgt acttgtcgtc cattttcttc agcaatacgc
     4441 tcaacgactt ccccagtatg tcgtaccccc tggcactggg atgcagccca tcctccagca
     4501 gcccgggttt tggggacact ccgtcctccc ccaggaattc ctcgccggga ttggcgaaaa
     4561 acacgctgtt tccgtcagcc aggccggata tcattttatt ggtttcccta atcaggggag
     4621 ccagcttttt ttcctccctg gggagaatgc ccagcaacag gattttggaa gaggggcact
     4681 tccggcgcgc caggctcaca aaagccttga gattgtctgc gcaggcccgg ggagcatcct
     4741 tccgcccgcc aagattattg gttcccagca gcacgatgat gacccgcgga gaaatgccgt
     4801 ccagctctcc cagctgcaag cggtaatagg cattatccac gtaatcggaa ccaaacccca
     4861 tattggttac cgcatgggaa gaaaacaggc tatgccaggc ggtttttcct gttccgagag
     4921 ccctgttgtc cccggaaggc tcgccgcccc agcggtgggt aatgctgtca ccaaagacga
     4981 catattccgg tttgacggtc cggttccgct ccatcactgc ttcatggcgt tttttccagt
     5041 catacacggc ccgcgggttc acctggggct tcagcgtggg cggcaattca tcagcacagg
     5101 caccggagaa acaagcaacg caaaaaactc ccgccagcaa taaacaaagg catgcataag
     5161 atttcataac ggtaagcgtt gagatactgc aatagagatt aggaaagtaa agagaaataa
     5221 tcttccgtca cttttccgca atcgcatgtt cccctcattt tccgctccgc aacggacaga
     5281 caggtgaaac atgccaaagc cagcgcaccc gcgttctctt cgcaaagaat tagccttgtt
     5341 gtcccccgga attcacgata taattacgcg gcgcggagtt ttgccgtttc cagcctttca
     5401 ggggctgcgg aacgtttttc tccagtcttc ttcactacat tctatttatg atcagcatag
     5461 taaaagactt gaaggagtcc accgcccttc cgcaggaatg gcagggattc aagccgggag
     5521 catggacgga gtccattgac gtacgggatt tcatccagca taactacacg ccctattccg
     5581 gcaatgaaga gtttctttcc ggcccctccc agcgcacgct tcgtttatgg gacgagctga
     5641 aagtcctgct gaaacgggaa atagacaacg gcggcgtgct ggatgctgat gaagaagtgg
     5701 tatcctccat cacatcccac aagcccggct acattgacaa ggaactggaa gtggtcgtag
     5761 gcctccagac ggacgccccc ctgaaacggg ccctgatgcc ctttggcggc ttgcgcatgg
     5821 cccaacaggc cctggaatcc tacgggttca agatgtgcga gaaaaccgca gacattttca
     5881 aaaagatacg caagacgcac aatgaaggcg ttttcgacgc ctacacttcc gatatccggg
     5941 cggcccgttc cgccgggatt attaccggcc ttccggacgc ctatggccgc ggccgcatca
     6001 tcggggacta ccgccgggtg gccctgtacg gcacggataa gctgattgcc gaacgccgca
     6061 aggacctcaa aaaccgtgaa cattcccccc ttacggatga gctgatccgt ctgcgcgaag
     6121 aaatgagcga acaaatacgc gccctggaag aactcgccca gctgggcgcc tcctacggct
     6181 gcgacctcac tcgccccgcc gcaaacgccc gcgaagccgt gcaatggacg tacctgggct
     6241 acctagccgc cgtgaaggaa cagaatggag cggccatgtc cctgggccgc gtttccactt
     6301 tcttcgacat ttatttcacc cgcgacctgg aacaggggct catcacggaa gaggaagttc
     6361 aggaaatcat cgaccagttc gtgatgaagc tgcgcatcgt ccgtttcatc cgcacgcctg
     6421 attacaataa cctgttctcc ggagacccca cctgggtgac ggaatccatc ggcggcatgg
     6481 gagaggacgg gcgcaccctc gtcacccgca gttccttccg catgctgcag accctgtaca
     6541 acctggggcc ggctccggaa ccgaacctga ccgttctgtg gtcccggaac ctgccggaag
     6601 ccttcaaaag cttctgcgcc aaggtttcca ttgaaacgtc ctccgtccaa tacgagaacg
     6661 acgacctgat gcgcccgcat tggggcgacg actacggcat cgcatgctgc gtgtccgcca
     6721 tgcgcatcgg caagcagatg cagttcttcg gagcgcgcgc caacctcgcc aagtgccttc
     6781 tctacgccct gaacggcggc gtggatgaac tcaagggcaa gcaggtggcc ccgccctccc
     6841 cccgctacac ggaggaaatt ctcaactatg atgaggtgat ggccctgtac gacaagatgc
     6901 aggactggct cgccaaaact tacattgacg cgctgaacat catccactac atgcacgaca
     6961 aatactgcta tgaacgcatt gaaatggcgc tgcatgatcc ggaaattctg cgcacgatgg
     7021 ctacgggaat cgccgggctt tccgtggcgg cggactccct gtccgccatc aagtatgcca
     7081 ccgtaaaagc catccgcaat gaagaagggc tgattgtgga cttcaagacg gaaggggaat
     7141 tcccctgtta cgggaacaat gacccgcgcg tggacgacat agcatgcagc ctggtcagca
     7201 atttcatgga aaaactgcgc aggctccaca cttaccgcaa ttccctgccc acccagtcca
     7261 tcctgacgat cacctccaac gtggtgtacg gcaaaaagac gggcaacacg ccggacggcc
     7321 gccgagccgg ggaaccgttc gcccccggag ccaaccccat gcacggaagg gacaggaacg
     7381 gagccgtggc ctccatgctc tccgtagcca agctgtccta tgacgactcc ctggacggca
     7441 tctcctacac cttctccatc gttcctcagg ccctgggcaa ggaagaacgt gaacgccgcg
     7501 tcaagctcgt ctccctgctg gacgcctact ttgccgctac aggtcaccac attaatgtga
     7561 acgtactgga acggaaaacg cttctcgacg ccatggatca cccggaaaaa tacccgcagc
     7621 ttaccatccg cgtttccggc tatgccgtga atttcatcaa gctgacccgg gaacagcagc
     7681 aggaggtcat caaccgcact ttccacaccc gttaacccgg actgcaagcg gatgccgcag
     7741 gtttttccac aaaaccatga tccggacgga gaaagctccg tcaccggttt ggttcattcc
     7801 gtggaatcct gcggcaccgt ggacggcccc ggcatccgct tcgtcctttt cctgtccggt
     7861 tgcagcctgc gctgccgcta ctgccataat ccggatacct cctacgtgcg gaggggccgg
     7921 ctcaggagcg cagatgatgt cctcaaggaa atagcccgtt accgggattt tttgcaggcg
     7981 gcgggcggcg gcgtcaccct ctccggcggg gaccccctct tccagccgga ttttgccggt
     8041 gccgtgctga aaggctgccg gaaactgggc ctgcacacct gcctggacac ctccggccat
     8101 ctgggcgtga atgcgggcga agaaatgctg gcggatacgg atctggtcct gctggatatc
     8161 aaggcatgga atccgaaacg gtatcgcgcc ctgacaggcg gggaactgca ccctacactg
     8221 gagtttgcgg aacgcctggc ctccctccgc aagcccgtgt ggctgaggta tgtgctggta
     8281 cctggcgtta cggacaatct ggaagaaatt gaggaactct cccgccatgc ggcgcttctg
     8341 ggcaacgtgg aacgcgtgga cgtgctccct ttccaccagc tggggagatt caaatgggat
     8401 gaattgaagc tggactatac tttgaaggac gtcccggaag cgtccgcaga actggcggaa
     8461 caggttcgcg gcattttccg gcggggcggt tttccggatt gcgtgcatta accggatttt
     8521 cgcgctttgg cgccaccaac cgcagcaaac cggacgcagg catccccctc ttccggatga
     8581 ggggccctct tccctccact acagaatcca tgcaaaaagg aagacgcatt tctggaattg
     8641 ctccggaata cggcatttcc gcaattcctt tcgttattcc atcattcttt acggcaacgg
     8701 cagcattccc gccatttttc cgccaacgcc ggggggcggc attccgcccc ttcccagatt
     8761 attctttccc ggaaatttcc cgcaaggctt ccagtacttc ccgcacggca atgtggcggt
     8821 tgcagggaac atcccggtca cattccttcc ggaagcaggg agaacagcac tggtggctgt
     8881 aaagggaacg gttgaatgtg cccatagggc ggtaaacatc cggaagccgg gtggaaaaca
     8941 gagtcaccac cggaagcccc cggaaagaac agagggacgg aaagtcgcca tccacagcta
     9001 ctgcagccgc agcgacatcc atgacgggaa agagagcctc cggcgcaccc accgccagct
     9061 ccacattcaa atgttccgcc agggaggcgg cacgctcccg gtcttcttcc agagccgcca
     9121 gcaccgtccg tcccggcaga agggaaacca gctccctcca ctgctccctg ctccattcac
     9181 tggcgctccc caggcgggaa aacggagcga ttaaaatggg ggcgtcttcc gccggggccg
     9241 cttttttcac agggaacaaa gacggggtgg cgacgtccag cccatgcagc ccccccaatt
     9301 gcagataaag ctgcacccgg tgcgccgggg gggcggcgcg caggacgggg gcctttaccc
     9361 ggaatttgta cttccgggcg ccgggatgca tgtccagccc ggaaaacatc atggggccat
     9421 acggttccag cgctttcagg gtttccatat ctccatccag catgacgccc agatccagcg
     9481 gtccgtcatt gtaaaattca tctgctgcca aagcttcccg aagctgcttc agggagtcgt
     9541 gcggcagcac atgggtaact tccggcaccg tcttccatat ccccagctgg gcagacgggc
     9601 agacgatgtt cacctgcatg tcgcaccgga cggttttcaa agcacgaatc aggggaacag
     9661 tcgccagggc ttcatccagc gccctgggaa cggctaccag aatgcggtac ggcttcagct
     9721 ccatattttc cagaagcgca gccgtttttt tatcctgcgg ggcaaagcgg tcaacggatt
     9781 tccagcggtg gtgcatccag aacacatcca gcacggattc ccggatcaac gtttccagcc
     9841 ccctgttcac ttcaatcgtg tcccctgcca gagagccgtc cgacctggaa aaatccacca
     9901 cattccccat atccgctatc cagtggccag gagcatccgt gcgcaccgct atggccacca
     9961 tgtccgcgcc agcccttttt ctcagcagag cgggcagcgg agtcgtgccg gtcaccttgc
    10021 cgaaaaaggg gacatacacc ccctcccata cgaactggtc gctcagcacg cccagggccc
    10081 ccccttcctt gagcattttc atgggagcct tgatgcctcc ctccttggag aacatctgag
    10141 ttccacgttc cgtgcgccgc tggtacacgt attcctccat cagcggattg tcaaactggc
    10201 ggtacatgga cccgtaacgc tccacctctg ggtaaaatgc gcgtattctc gccagcgcct
    10261 cccagttgcc ggagtgggct atggcgcaaa cctgcccgcg cccttccagc acaggcgcgg
    10321 caaactgttc gtgccctccg accgtcacgc aatgcttcaa ctgctcatcc gtcagggtgg
    10381 ccgtcttcgc ggaacacagg aaattggcaa tggtcctttt gaaattttcc cggcttaatt
    10441 tctgcagttc ctttccgcgc agggccggat ccaaaacgat gcgcagattc ctttccacaa
    10501 tgttccggcg ctggggaagc agatgccacg ccacggcccc tgccgcgcgc cccagccggt
    10561 acagcgtttt catgcccacg agcttcaaca gcccttccat gagcagaaac cctttcattc
    10621 ccaaatgatg ggcaaacgta ttccgggaag ccggggagga atcaggagag gaagaatcag
    10681 tcataaggaa aaccggaaaa gatgttatac gaatcccctc cggtccacaa accctttatt
    10741 cccccggcag aggtcccttc ccgcatttta ttttcccggc taaatgacgt cttccctaaa
    10801 tttttccgcc ggcgcggaat ccaaagccat cccatgcttt actgcatctt cctcataaaa
    10861 gcatctctgc ggagacggca tcttactttt ggcaaagaaa tgactttaca attcttaact
    10921 aaacggtata ttccgtctcc cgaaccgaac accaaaccgg agttatacac catgaaagtt
    10981 ctttcttcct tagcctctat gaagcgccgc cacgcagact gccaaatcgt gaagcgcaag
    11041 ggcacgctgt atgtgatctg caagagcaat cccaagttca aggcccgcca gggcgctacg
    11101 gcaggcacgc gcctttccaa aaagggcgtc aagtaatccc tggcccagca cagatttcaa
    11161 gaagaccgcc gcccgccggg tgccggtctt tttttgctga ccaagcccct ttccgtacat
    11221 ccatgcagct tcctgccgtc caaaccaaat tcctggatct tcccaactcc ttctccctga
    11281 gaaatggagc tacgctggac aaggttcgcg tcgcctacga acagtacgga accctgacgc
    11341 cgaataaaga caacgccatc ctgctgttcc atgctctttc cggcagccag cacgcctacg
    11401 gttacaatcc ggaagtcccg ggcatcggtt ccctttggaa accggaaaac cacgagggct
    11461 ggtggaacag catcatcggc cccggcaagc cgctggacac aaactgcttc tgcatcatct
    11521 gcgccaatta cctgggaggc tgctacggca ccacaggccc cgctaccgcc tgccctgcag
    11581 acggccagcc ctacggctcc cgcttcccgc atgtggaggc cgcagaccag gctcgtctcc
    11641 aggcccttct gctggacagc ctgggcatag aacgcgttca tcttatgggc ccctccgtgg
    11701 gcggactgat cgccctcagc ttcgcgtgcc agttcccgga acgggtccgg agcttcatct
    11761 ccatcggctc cggttaccgg gcttccatcg aacaccgcct gtccctgttt gaacaaatcc
    11821 tggccattga gcttgacccg gatttccaag gcggggatta ctaccgggga ccagcgccta
    11881 aaaaagggct ggcgttcgcc cgtatcatcg gccacaaatc atttgtttac caagaggggc
    11941 tggaacagcg cgccagaaaa gaggtgggag gcaactacgg cctgctcacg tggatggccc
    12001 ccacccgcag cacgcaaagc tacatgcttc accagggaac caagttcgcg gagcgctttg
    12061 acgccaacgc ctatatccgt attgcggata tgtgggcgga gttcgacatc cgcgaccaca
    12121 ccccggacgg aacatttcaa accgccctgg aaggcttccg ccgcgcaggg attcccgcgc
    12181 ttatcttttc cattgataca gactgctgtt tccgcccggc ggaacagcag gatttcgcgg
    12241 cgcagcttga agccgcccat attcccacgg agttccatac catcgcttcc accaaggggc
    12301 acgattcctt cctgctggag ccggagcttt atgcggaacc catccggcgc attctggcgg
    12361 caagggagcc gaaggggacg gcgtaagctt tttcccgccg caagaagaca cggcgaagca
    12421 acgcttaaaa agaagtgatg ccgggaaccg gaagcaagag ggaaaaatca accatgtcat
    12481 gaaggaacgg ccaggttccc tgcaaagcgg aacttcacgg ctcttcaacg tgaaaataac
    12541 ctgaaccgga tgaacccgaa cagggttttc gctgtcacac cttcatgact gatcattatt
    12601 acacctccga aacggagaac gtcggacaat tccgctgcga aaccaccttt attccttcca
    12661 acgtcacgtt tgccacggac ctgcccgctt cttttgaagg ccgcgcagaa ttcccctccc
    12721 ccggagtttt gctcggttcc acgctcgcct cctgcatgat gagcctggtt tccgtggtcg
    12781 cggccagaaa aggagtggat ttgaaaggca tgcgcgttct ggcgcgtgcg gcggaatcat
    12841 ccaagggaat tgaaaaaatt gaactgaagg caatcatgcc cctggaaggc agccaccctc
    12901 tccgcgccat gctggaaaaa accgccttgt cctgccctgt gcgccaggcg ctgcggcccg
    12961 atctggaaac gcccattgaa tgggaatgga agtaagcagc catcaggaac gtcaacccaa
    13021 gcttgaagtt atccttaaag aaatcccgcc cattcatgaa aaaagccgct gcggaatcat
    13081 ccgcagcggc tttccaattg gccgacgttt tttcctttag aagttgtagc ggtagccgat
    13141 actcccgttg atggagctgg aaccgctgcg gatatccgca ttgccgtcca caaaaatgac
    13201 gccctgggtg cccacgggaa cgctcagccc cgcgccaatc tggaaggccg tgcttccgac
    13261 cttggcgcca tacaccggac gcgtatagga gggatctgcc aggaagccca cattagcctg
    13321 cccgcggcgg tctcccatat cctgggaaac gttcacccgt acttctccca gcgcttcacg
    13381 cccgaagata ttggacccca tgagtccgga gagccgggca cccacagcga cagcagccgt
    13441 agtcagttcc tggtcttcca ccttcagtcc ggcatttccg gcagaaccgc tttcccgata
    13501 gccgtccatg cgggtcgtca cgatggaagc gttaaacaaa ggctggagaa tcacgctcct
    13561 gtcttcattg agagcgatgt catacgccaa ctcgtacatg gcgccgaaac cggctcccgt
    13621 cgtattgccg cgggcctggt aagaccccgt accgtaattc accgtgcgcg tcagcgaggc
    13681 atcattccag ccacccgtca gaatcagcag atgggaccat ttacggtact ggtagcgggc
    13741 gaacagattg acatagtaac tgtccaggtc tccgtccgcc gtatccgccg cgctggccgt
    13801 caggcttccg taattggcag taaacgcagc tcccgcagtg aggcggtcgt tgatatccac
    13861 gtccatgcct accgtgcctc cccaggtggt gagttcgtag ccgctttcat cccccctggt
    13921 gtccagcttg gcataagacc cggttccctg catccacata tggaagtagg gcatgtcttc
    13981 atggacatat gcagggttaa cgcccatctg cgccacgcgg ttgcgtatcc agcccatctg
    14041 gtcgcgcagg gagtcgcgct gggcgatgcc caggctggta accgtgctgc cggcggcggc
    14101 ggccagtttg cgggcggcgc cggaatagtc gcctgaattc tgggagagaa gaacagaggt
    14161 atagaaatcg cgcaaggcag agccttcctc catgtgatag cgggaattcc aaaggatgtc
    14221 cgctccagta gcggcattcc gcgtcaggga agagtcacgg aaaatgtttt ccgtgcgcgc
    14281 cgtaccggtg aggatgatgg ccgtcatgct gtcattggtg gtcagctcca ggttttcata
    14341 catggaacca agaatcatgt cctggagggt gacattgtca cccagggaca ccagcgcgcc
    14401 gtccgttgtc ttgaacaatt ccatattcag cgtttccgaa ctcccggaaa ccagggtatc
    14461 cagattgttc atgaccagcg tgacttcccc cgtcccgtct cccagcgtaa tatttccgct
    14521 ggaggtgaca aagggattgc ccaggccgtc caccgttgtg gaggaagtgg taatggccac
    14581 tgtgctgtcc cctgtcacgc tcaagccgtc cgagccaagc gtcagctggg ttttgggatc
    14641 gtctgcgctg ccgatattga gcgtgccgcc gttcacggta atcccctgat aggaagcctg
    14701 ggcgggattg ccgccctccc ctgccgctcc ggccagggtc agcacgccgc cgtcactcac
    14761 attcaggtga taacctgcat tgcccgcacc cttgatagtc tggacgcttc cgttgccgga
    14821 tttgacgttg agcgttccgg atgccccgtc cagcgtaccg gtaaaggtat gggaatcgga
    14881 agagctgatc gtcatttccg caccgctcag cttcagagct ccgccgccct ccagtccgga
    14941 aacggtattc acggaaccgg ttgcagcgga cagggcggac ccttcacgga tatccagcag
    15001 gacaccgttc agggaagagc cgttgcccag tgtcagggag gagtctgttc ccgtaccacc
    15061 caaggtcagc gtaccgtccc cggagatagt cacttccgtg acatggctgc cggcctgctg
    15121 gccggtaaga accatctggg ctccgttacc caaattcagg gttccccctc ccgcgccggc
    15181 agccagcgtc tccaccgtgg ttacacggga ggcgccgtca ttccgtccgc ccagcgttat
    15241 gtctccgccc gcgagttcca gcgtagtaag gctattgcct gcaccgttca ggatgatatt
    15301 tccctccgag gaactgagac tggagtcatt cccggtgaag tttccttcta cggtgagggt
    15361 ttccgcacct ttcttgacaa aatccacatg gtccccgctg atggttccgc cgtagctgtt
    15421 gccgccggcg tcaacatcct gaaccagatc caccacggcg tggttggaag ccgcatcatc
    15481 cgccgtattc gtcacggtca gcgcaccgtc gctgccaacc aggttgctga ctttcagacc
    15541 gtccccattc cgggaggctt ccggagcccc gttcaggctc acatgaagcg tggtgccatt
    15601 aatgccgaca gccttgtagg gatccagcgc ggcgtaatct ctgatattgg ggttgtctga
    15661 attgggggtg gtgtccacca gatagacaag atccgtattg ccgctgacca tcagcgtccc
    15721 gtccgcaccc aggacttccg tcacggtata gccgagggaa gccaggagag gagagaatcc
    15781 gatttgcttg aaattatcca cagccagggt tcccgttgtc agtacaagcc ctacgccgtc
    15841 agtggaatcc cggttggcgg caagcaggtc cagaacaccc tggttgctga ggttgatggt
    15901 tgttgtggcg gctgaaagcg tcaggctgtc cgcatcaata acgccctgtc cggtagttcc
    15961 gaccgctgta aggctgccgg aatccagttt cagcgtcacc gtcttgcccg tcatgtccag
    16021 agcaccggaa acgcctgtaa gccgggagta atcctccatg acgatggagc cgaccatgga
    16081 gccggacagg ccgcccagat tgatggtatt cagggctccc tgcgttccgg cggaagcggc
    16141 cacttccacg tttccagcgg ttttggcttc cgcgtttgcc aggcttccct tcgtaatcag
    16201 aataacgttg gccgcatcca gggaggacag attgagaaca ccgttattga cggtgacccg
    16261 tccggacccc agggagtcgg cccccgccaa ggtgacggtg cccgttccgg agagcgtcgt
    16321 agaaccggtg aacccggtgt tgccggccgc cagcgttatc tctccagcag tgtcaataac
    16381 cagggaacca gctccggaga gggacccggc ccagacactt ccgtcaccca gccgcgccgt
    16441 agcgccgccc gcaatggaga gtgcgcccag gaaggtgttc gctccggtga gttccagcgt
    16501 tccggcgttt acggataccg tgctgccggc cgtaccgctg atgacgcctc cgtaggagaa
    16561 atcgcgggca aaggccagcg tggagttgtt ctggatgtca atgctgtccc ccagcttggc
    16621 cacatcggcg gaattcacgg taaccgtgcc gcggtgcacc ttgagctgac cgtccaggtt
    16681 gacgccgccc gccagggtaa tattgcccgc tccctgggtg gagaacgccg ttccgctcaa
    16741 atcgccgctg aaggtgaaat ccttggtggc aaagacctgg ttgcccgtaa agacaacgtc
    16801 attggcaaac gttcctccgg ctgttccgtt ccattccgta cggacgttgg aatccgcaag
    16861 tttcaagatg ccgtccgccc ccatcgttac gttattcaat tggaaatagc cggatgtcac
    16921 ggacaggatc ccctggaatt ccgtgctcat attcaggaca ttggccccat agctggttcc
    16981 cagtcccacg gaaacggtac cggaaccgga ggcattcagg ttcagagccg agttatcatt
    17041 agccccgctg accgtcagta cggaaccgtc cgccaattcc acggcttttc cattggccag
    17101 agccttggcg acggtggcgg ccacttcctc gcccagcgtc acggaaccgc ccgtccacgt
    17161 catgttgtct gcggtaaacg ccgtggcaaa agagccggaa gccaaattga ggcggccgcc
    17221 ctgcaggttg atcatgccca ttcccggttg aacgtccgcc gtagccagag tgagcacgcc
    17281 gtccgtaacg gtaatggctc cggatcccag ggaattggcg acctgggcta ccagttcgcc
    17341 ctgctggacg gaaatatccc cgttccagcc cgtgttgtcc aaattaagga caagcttccc
    17401 ttcgccgcgc ttggtcagcg ttccctgggc gatttttccg gtgccgtcgg aaacgaagac
    17461 ataatcgctt ccggcagcat tgttgactgt gatggaagca ggattcaccg ctccggacag
    17521 agtgacggtt cccgccccgg tactgttgaa gatcagattc ttcccgacag ccgtatccgt
    17581 ggaaccttca atgccccaca tggcgcccgt gttcgcatcg ctccaggtca ctccttccgc
    17641 tccctgccag atccatacgt ccccggcgga agtcactacc agcttgaggg atgttcccgt
    17701 ctgctccagt tcataaatca gcgtttcgtc cccggtatat ccggcccagt taaagacggc
    17761 gctggcggca tcaagaccgc tggcggcgga aatcagggta tattccccgg catccgtaat
    17821 gccttcaagc ccgttcagtg taagattgaa cgttccggcc ccgaaagcgc cgcccacttc
    17881 gagggcggag ctgatatcca gtgtcagcgt agagttgacc gccaggttca gggcgcccgc
    17941 agtcgtcatc cgcgtattgg ccgccatcgt gatattcccc agggacgtag ctccggaagc
    18001 agtaagagcg agcgttcccc cctgaatatc cgtcagcccc gtgtagctga ccgttcctcc
    18061 cagcgtcagc gtttcctcgc cgaccttggt cagagacagg acgccggatt cgtcatacga
    18121 aatggaagtg gctccgtacc caagagcaac accacggtct gtgagcgtgc cgttgtacgt
    18181 gccggctccc accgtcagcg tgcgcgcacc gcctacggct cccacctggg aattttccgt
    18241 tccatccaga gaggcaattt caacatcccc cagcacgcgc atgaaagcga atccggtcgt
    18301 gtccgttccg gatgtcaggg tgacgccacc ctgagagatg gaagtgcgca gatccagccc
    18361 ggcgctatag ccgttggaag cattcatggt gatcattccg gtaaatccgg aagcgtctcc
    18421 gctgatgatg agctttccgt tggaattgta cctgccgtcg cccgctccgc ggctgtaagt
    18481 cagagaaccg gctccggtga gcgttccggt g
//
