LOCUS       c00044_gnlPro..         6471 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKBKLHLK_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:53:56
            Original ID  :: gnl|Prokka|JKBKLHLK_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6471
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6471
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2767:6257]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2768..6257
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..6471
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6471
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             73..780
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPEAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             1210..1443
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(1477..2262)
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LVCELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(2295..2567)
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             2768..3469
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_5"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3491..5449
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.7e-55, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             5490..6257
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_7"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-24, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.4e-12, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 cggattccaa attcgttatt caagcacaag tgcatacatt gaaccttgaa tcattttatt
       61 aagatactga ccatgaataa attattatcc accctgattc tttcggccgg catgagcctg
      121 agcgctaccg cggctaccgc tctgttggat agctccatcg tgggatattc ggactttgcc
      181 tcccaaacgg cggatttcgg cacccggaaa gattccgttt ccatcacgtc tgacgacagc
      241 aatctgacgt tgtccgggat aaccttcaac ggatacggtg ccaacaaccg cgacgttatg
      301 tctgtgacga tggttcttga cctgtccaaa atcaacactc cggaggccta taccgctctg
      361 tttaacgcca aaaacagcag tgtaagctgg ggcgtgggcc tgaacacgga ccggaaactc
      421 cagggattat ggaacaacac ctcatacagc gggcccgtcg ttgacacccc gctgggcacg
      481 gaaggttccc tgaccatttc cgtagtcacc ggagatcttg gcacccgcat ctattttgga
      541 gacagcgcta cgtactattc caacagcggc ctgaaattcg gcaaccagca aattaatcag
      601 attctcatgg acgcaggact ggctgaatcc atcgaacagc tctacatcca cgactccctc
      661 ctttcccagg aacaagttgg tcagctgatg agtgaaatcg ccagcattcc ggaacccgcc
      721 acggcttccc tgggcctgct gggactagcc gcgctgatga tgcgccgccg cagggcataa
      781 gcctgtaccg tccgcctccc tatattcaaa ggccggctca caaaatcgtg agccggcctt
      841 ttccttatcc gttcaaacat ctgccggaaa aaacaggggg aagaagcttc tatttgctgg
      901 gtaccctcac ggccagcact tgacggggaa atggcattca ggctcccccg ggagggtcat
      961 ttcaagagct tccggccccg ccccacttcc gtacacgccc ctttttccca tgccgggaca
     1021 gccggaaccg gagcatgcaa agcccggctt ccctcagcat ccggaacagc ccatcctttc
     1081 agcaatccat ttccccgcac ggtccggatc gctgcggttt ccgtccgtcg gcaacagact
     1141 ccttccccga aacagggaaa aggagtggga aaatggctga gcttgaacct ttatcccccg
     1201 ttcccgtcca tgaaccttca aaaacagcag ctgctactgc gcctgttccg gtatttcaaa
     1261 agcagaaaag gagaaccgcg ttttttcaac aaacggaata tatgccttct ggccgccgcc
     1321 ggcgcctaca tcctgactcc cgacgaattc ctgtttgacg gaatcggcag gctgggcctt
     1381 ctggatgacg cggcggtcat cctgggcgcc gtcctcaccg tctttttccc ggacggggac
     1441 tagagggccg taccctccgc cgcgcctcgg gcggaattag cgggacgaca ctttccggaa
     1501 cttcggggac tgtcccatga atgtctccgg attttccagg agaagacgtt ccgtttcctg
     1561 ccgggaaaaa ccgcgcctgc gcagctcgca gaccagggcc gtcagcgcca ggggatcgga
     1621 atccccccag tccgccgcgg aattggccca gacacggtcc attccgtaca attccagaat
     1681 atccgccgcc cgcttgggat tcagcttgct ggtgggataa agggtcagcc cggcccagta
     1741 accggcctcc ttcaccagcg ggaaggtatg ttcctcacag tgatccacca gcacgcggca
     1801 agggtccaga tccggacggt ttttcagggc ggaaagaatc attacggtcc ccttaagctt
     1861 gtcttccaga tggggagtgt gaatcagcac aagctggttg aggcgcaccg ccagatccag
     1921 atgctcttca aaaatagtca tttcatggga agtattccgg ttcagcccta tttccccgat
     1981 gccgaggaca ttgggccggt caatgaactc cggaatcagt ttcatcacat cccgcgcgaa
     2041 agccacgtcc tgcgcctcct tgggattgat gcacagccat gtgtaatggt ccatgccgaa
     2101 cttggccgcc ctggcgggtt cgcattccgt aagctgtacg aaataatccc ggaaaccgtc
     2161 cgcggacgaa cggtcgtaac cggcccagaa cgccggttcc cctaccgcca ggcagccggc
     2221 ctgcgccatg gcccggtatt cgtccgtggt gcggcacacc atatgtatat gaggttctat
     2281 gaaagccatc attcttattt gctgaggttc ggggctccgc aggccgcttt ggctgcggcg
     2341 gtttccggca cggtgtcatc cctgtaggaa agggcttcca gaatggcccg gacgcgtccg
     2401 gggccggatg cggacaagag gggaagaaca tccatcaggg catggtagcg gaaatccgcc
     2461 tccccttccc cgcggtccac ccggtccaga aatgcggcca catccagaac gccggcgcgc
     2521 gccgctgcga aatccgcgtc cagcacctcc tttttacttc ttttcatgca cagacgatac
     2581 gcctatgcgg aaagcctcgt caagccggaa caggcaacaa aatgataacc attccaaact
     2641 gataaacagc aacctctttc cccggttttt caaaaatccg aaaagcgccg gaaattcaag
     2701 aagaggcttg ccatccgggc ttgaaccggg catcctgtga agacgcattt atttcattag
     2761 agcgcctatg aatgcactag taaaaaccat atgtacattc gtgacatcct ccatcggccg
     2821 caaaatcatt gtggctctga cggggttatg tttggtcttg ttccttgcgg gacacctggc
     2881 aggcaacctt ctcatcttcg gaggccctga atggatcaac acctacgccc acggcctgca
     2941 ctccatgccg gaagcagccc tctggggaat ccgcgcgggg cttgcggtga tcttcatcat
     3001 ccacgtctgg ctgaccatcc agctgaagct ggaaaaccat gcggcccgcg aaccctacgt
     3061 gttcaagaac accattaagg caacgctctc ctcccgctac atgatctata ccggtttgac
     3121 cgtcctggtg ttcctgatct accacctgta ccagtacacc ctgcgcgtgg gatacgaccc
     3181 cgcccagttc accaccttca tttccgacgg tacggtggaa acctttgacg tgtacaagat
     3241 gatcgtgacc ggattctcca acgtatggtg ctccgccttc tacatcctgg ccgttctgat
     3301 gctgttcagc catctgcgcc acggggtaca gtccatcttc cagactgtgg gcgtcgattc
     3361 ccgcaaaatc cggcccttct acaactttat cgccatcgcc tacggcgcga ttatctgcct
     3421 gggcttcatc tccgtgccgg tctcggttct tctgggtatc atcaaataac cattaactcc
     3481 tctcaaagtc atgattaatt ttcccgtaag cgactggatg ccggatgcca aaattccctc
     3541 cggccctatt caggacaaat ggtccaaata caaacttgag tccaaactga tcaatccgaa
     3601 caacaagcgc aagtacacgg tgcttgtggt aggttccggc ctggctggcg cctccgctgc
     3661 cgccacgctt gccgaacttg gctacaacgt caaatgcttc tgctaccagg acagcccccg
     3721 ccgcgcccac tccattgcgg cccagggcgg cattaacgcg gccaagaact accagaacga
     3781 cggcgactcc gtttaccgcc tgttttacga caccgttaaa ggcggcgact tccgcgcccg
     3841 tgaagccaat gtctaccgtc tggcggaagt ctcctccaac atcattgacc agtgtgtggc
     3901 ccagggcgtt cccttcggcc gtgaatacgg cggcctgctg gacaaccgct ccttcggcgg
     3961 cgcccagctc aagcgaacct tctacgcacg cggacagacg ggccagcagc tcctgctggg
     4021 tgcctaccag gccctggaaa aggaagtggc caagggacac attgaaatgt tctcccgcca
     4081 tgaaatgatg gatctggtgc tggtggacgg cgaagccaag ggcatcgtca cccgcaatct
     4141 ggttaccggc gaaatcaaat cctacgcagg ggataccgtc ctgctctgca cgggcggcta
     4201 cggcaacgtg ttcttcctgt ccaccaacgc gatgggttgc aacgtcactg ccgcctacaa
     4261 agcctacaag cgtggtgcct tcttcgccaa cccctgcttc acgcaaatcc accccacctg
     4321 cattccggtc aaaggcgact accagtccaa actgacgctg atgtcggaat ccctccgcaa
     4381 cagcggccgc atctgggtgc ccaagtcccg tgaaaccgca gaaaaaatcc gtaagaagga
     4441 aatcaagcct tccgatgttc ccgaagaaga acgggactac tacttggaac gcaagtatcc
     4501 ctccttcggc aacctggctc cgcgcgacat ttcctctcgc gccgccaagg aagcctgcga
     4561 cgacggccgc ggcgtggccg tcaccggcaa gggcgtcttc ctggattttg cggatgaaat
     4621 caagcgcatg ggccgcgaat ggattgacgg ccaatacggc aatctgtttg acatgtacga
     4681 agaaatcacg gacgacgacc cccatgaaac gcccatgatg atctaccccg cctcccacta
     4741 caccatgggc ggcctgtggg tggactacaa cctcatgtcc aacgtgaagg ggttgcacgt
     4801 cctcggtgaa gccaacttct ccgaccacgg cgccaaccgc ctgggagcct ccgccctgat
     4861 gcagggcctg tctgacggct acttcgtcat tcccgccacg ctgcccgctt acctgacgac
     4921 caccaagccc ggtgccgtca ccaccgccgc cccggaattc aaggctgcgg aagacgaagt
     4981 gaaggaacgc atcaacaagc tcctgaatgt gaagggcacc aagacggtgg actccttcca
     5041 ccgggaactg ggcctcatca tgtgggaaga ctgcggcatg gcccgcacgg aagaaagcct
     5101 gacccacgcc attgaacgca ttccccagct ccgcaaggaa ttctgggaaa acgtgcgcgt
     5161 aaccggcacg gcggacggca tcaacgcgga actggaaaaa gcctgccgcg tggccgactt
     5221 cctggaattc gcccagctgc tctgctatga cgccctgaac cgccaggaat cctgcggcgc
     5281 ccacttccgc gtggaatacc agctgccgga cggcgaagcc aagcgcaacg acgatgaata
     5341 cgcctatgta gccgcctggg aatacactgg cgtggacagc ctgcctgttc tccacaagga
     5401 accgctgacc ttcgagaacg tgcaccttgc catccgcagc tacaagtaaa gatagccaat
     5461 acattaacac tcaaaagaaa gattataaca tggctaaaac actcaatctc actctcaagg
     5521 tctggcgcca ggaaaaccgg gaagccaagg gccgcattga gacctatgcc gccaaggaca
     5581 ttccggtgga cgcctccttc ctggaaatgc tggacatcgt caatgaaggc ctggtcaagg
     5641 aaggcaagga acccatccat tttgaccacg actgccggga aggcatctgc ggcatgtgct
     5701 ccctgaccat caacggcatt ccccacgggc cggaacgcca ggtgaccact tgccagcttc
     5761 acatgcgcaa gttcaaggac ggcgataccg tctggattga acccttccgc gcgaaggctt
     5821 tcccaatcct gcgggacctg atggtggacc gctccgccct ggaccgcatc atcgccgccg
     5881 gaggctatat tgacgtgcgt accggttccg cgccgaacgc caacaacatc gccgtggaaa
     5941 aagtgaaggc ggacgccgcc tttgacgcgg ccgcctgcat cggctgcggc gcctgcgtgg
     6001 cctcctgtaa aaacgcctcc gccatgctgt tcacctccgc caagatcgcc catctcaatc
     6061 tgctgccgca gggccagccg gaacgttcca agcgcgtcct ggccatgatg aagcaaatgg
     6121 aagcggaagg cttcggcaac tgcacgaacc agtatgaatg tgaagctgct tgcccgaaag
     6181 gcatcagcgt ggacaacatc gcccgcctca accgcgactt catgcgggcc aacgccaagg
     6241 aaggtctctg tttctaaaga agattccttc ttaagacgct ctgtaaaaac tcccggcggc
     6301 atcggctgtc gggagttttt ttcattatca ggtttccttg aaccaggaat aaaatatcag
     6361 acagttgctt cctcatcgtc gcgcagcgta aaaaataaat gttacactgg aaggttccca
     6421 gtaatccagg agactgtact tggaaatgcc ggacgaaacc taagcaagcc c
//
