LOCUS       c00163_gnlPro..        12498 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JCOLNFCF_163.
ACCESSION   c00163_gnlPro..
VERSION     c00163_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:35:13
            Original ID  :: gnl|Prokka|JCOLNFCF_163
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12498
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12498
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1567:11564]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1568..11564
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..12498
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12498
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..811)
                     /locus_tag="ctg163_1"
                     /transl_table=11
                     /translation="MKRTLWFIFFLLNSLFYLYADSENDSLLKVLDKVISERLIYTQKK
                     EATIKELKKKKVGLNSLEDIYNLNKEIIHQYETFVCDSAEQYIHENIDIAKTIGNKEYL
                     LEEQLRLAFVYSLSGLFIQANDIFKSIKCADLPDHLKALYCWNRIRYYENLIKYTDDVR
                     FSNEYISEKEAYRDTVMSILFDQSDEYRKEKAVKLQDKGSTKEALLILTEIYDKQEPSS
                     HGYAMMAMGLARAYRLIGNYALEEKFLMLAAMTDTKLAVKENEALLTL"
     CDS             1072..1449
                     /locus_tag="ctg163_2"
                     /transl_table=11
                     /translation="MKQSLKFGLLLVLALLIHCATNGAMEDMCKVSSPTYRQEKCYVSQ
                     DRPIQDALERLYNLYTTQTCDMSHTDVAHVPTDKSMFLLIAYFCDHYKHQSPPYPVSSH
                     SPTYYYDPISYYIYGLRKIVI"
     CDS             1568..1918
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_3"
                     /sec_met_domain="Oxidored_q4 (E-value: 2.9e-38, bitscore:
                     119.9, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVVALSRAISPRSYNLQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMRDMGPQGLISVLFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             1909..2511
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_4"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.1e-26, bitscore:
                     83.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVALGVLDDF
                     INWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGVNRKEKKPDYLRNEE"
     CDS             2594..4186
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_5"
                     /sec_met_domain="Complex1_30kDa (E-value: 1.1e-36,
                     bitscore: 115.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 8.7e-66,
                     bitscore: 211.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEIQFIAPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEKDAP
                     EKLRGLGVVYHLESTITGERIALKTATTNRELPEIPSVSDIWKIADFYEREVFDFYGIT
                     FVGHPDMRRLYLRNDWIGYPMRKDNDPEKDNPLCMTNEETFDTTQEIELNPDGTIKNKE
                     TKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEKMNESLTYP
                     QTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVQYIRTIMDELQRIDSHLLFYSC
                     LAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNFVKRVKEFI
                     PYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMP
                     YGVYDKVDFKEIVYTEGDCFARYLVRMDEIMESLNIIEQLIDNIPEGPYQEKMKPIIRV
                     PEGSYYAAVEGSRGEFGVFLESQGDKTPYRLHYRATGLPLVAAIDTICRGTKIADLIAI
                     GGTIDYVVPDIDR"
     CDS             4207..5283
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_6"
                     /sec_met_domain="NADHdh (E-value: 4e-123, bitscore: 400.2,
                     seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSIMPEGLAIFIECVAVGVCLVALYAILAI
                     ILIYMERKVCGFFQCRLGPNRVGKWGSIQVVCDVLKMLTKEIFMPKGADHFLYNLAPFM
                     VIIASFLTFACIPFNKGAAILDFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLTGTMQFSEIVEGQADGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNAVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             5296..5784
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_7"
                     /sec_met_domain="Fer4_7 (E-value: 3.2e-13, bitscore: 40.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.8e-06, bitscore: 15.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYKDKKYTYLGGLMHGISTLATGMKTSIKVYFRKKVTEQYPENR
                     KELKMFDRFRGTLNMPHNENNEHRCVACGLCQMACPNDTIKVTSETVETEDGKKKKILA
                     TYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRAKLVLKLNHDGSKVIEKKKEV"
     CDS             5787..6299
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_8"
                     /sec_met_domain="Oxidored_q3 (E-value: 4.5e-38, bitscore:
                     120.0, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKAKRSKVLAGLFTMIAG
                     LAIILFITLKHDFMQTANLAPQEISIHAIGNALLSSDKYGYVLPFEAVSILLLACIIGG
                     IMIARKR"
     CDS             6337..6645
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_9"
                     /sec_met_domain="Oxidored_q2 (E-value: 2.9e-22, bitscore:
                     68.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDELKW"
     CDS             6700..8589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_10"
                     /sec_met_domain="Proton_antipo_N (E-value: 2e-25, bitscore:
                     78.5, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.5e-87,
                     bitscore: 283.2, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFFSFLILGIGGKWMSHRTAGTIGTLILGAVAVLS
                     YVTAFQYFSAPRLEDGTFATLMPYNFTWLPFTETLHFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGEVGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFVGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIAYA
                     PNTLHMVAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMDPHEGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPVMGWVMTVIAAMTAFYMFRLYYGIFWGKENKELH
                     AHHTPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIHLDPSVAITSVVIAI
                     ISIAIATWMYKNAKQPVADSLEKQFKGLHKAAYNRFYIDDIYQFITHKIIFRCISTPIA
                     WFDRHVVDGFFDFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGALALILLLIL"
     CDS             8603..10087
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_11"
                     /sec_met_domain="Proton_antipo_M (E-value: 9.6e-69,
                     bitscore: 221.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFLYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISVDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELAGLMKVMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDQFHRVLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLELTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             10125..11564
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_12"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.9e-73,
                     bitscore: 236.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLYMREELSLIAVLLLLFLADLFMSPDAHKNSGKARLNTM
                     LPVILMAIHTAINLIPGTATDAFGGMYHYVPMHTVVKSILNVGTLIVFLMAHEWMKRED
                     TSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEAG
                     AKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMAFIFFFTGMAFKLS
                     LVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLLAVLIKVFAPMINDWQEVLYWVTI
                     ASITIANIFAVRQQNLKRLMAFSSISQAGYIMLGVIGGTAQGMTALVYYVLVYAAANLG
                     VFAVITIVALRSQKFTLEDYAGLYKTNPKIALLMTLSLFSLAGIPPFAGFFSKFFIFMA
                     AFDAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTLG
                     IIGLGIASIVYQSIDKLSFGI"
     CDS             complement(11704..12498)
                     /locus_tag="ctg163_13"
                     /transl_table=11
                     /translation="PEENEIEIIGINYDITELKETEAELIQARDKAEMMDRLKSAFLAN
                     MSHEIRTPLNAIVGFSDLLVETEELEERQEYIKIVRENNDLLLQLISDILDLSKIEAGT
                     FEFTNGDVDVYLLCEDIVRSMRMKAKGEVELVLDNHLPVCHVISDRNRIHQVISNFVNN
                     AMKFTSEGSIHVGYKLKDGELEFYVEDTGIGIEKEQLPHIFERFVKLNSFVHGTGLGLS
                     ICQSIVEQLGGRIDVDSEKGKGSRFWFTIPGVIVTEEVGCAR"
ORIGIN
        1 ccaatgtcaa taatgcctca ttctctttga cagctagttt tgtatctgtc atagcagcca
       61 gcattagaaa cttttcttcc agtgcataat tcccaatcaa ccgataagcc ctggcaagtc
      121 ccatagccat catagcatag ccatgagatg acggctcttg tttatcatat atctctgtca
      181 aaatcagaag agcctctttg gtacttccct tatcttgaag cttcacagct ttttcttttc
      241 tatattcatc cgactgatca aataagatgc tcatcacggt atcccgataa gcctcttttt
      301 ccgatatata ctcgtttgaa aaacgtacat cgtccgtgta tttaatgaga ttttcataat
      361 aacgtatacg attccagcaa tacaaagctt tcaaatgatc gggtaaatcc gcacatttta
      421 tcgacttaaa aatatcattt gcttgaataa acaaaccgga taaagaatag acaaaagcca
      481 accgaagctg ctcttccaaa agatattctt tattaccgat tgtttttgct atatcaatat
      541 tctcatgaat gtattgttct gccgagtcac agacaaaggt ttcatattga tggataatct
      601 ctttatttaa attgtatata tcctccaacg aattaaggcc aaccttcttt ttctttaatt
      661 cttttatggt agcttctttt ttctgggtat atatcaaacg ttcagaaatc actttgtcta
      721 acaccttcaa caaagaatca ttctcactat ctgcatagag gtaaaacaag gagtttagaa
      781 ggaaaaatat aaaccaaagt gtgcgtttca taatcatgta ttctttctta atctgcaaaa
      841 aaatgtattt tctttgtgtt attcgccaaa aagagcgtaa atcattcttt ttattgcatc
      901 ttttaacaaa tgaagatgga gaaattaccc cattctaaat gatatttgtg aaaccatgct
      961 gactaaaaaa tgaatctaaa agatatggag ttaaaaaaag cttttttgcc atacggactt
     1021 tgcaaaaagt ataaatatta gttctatatt tgcagccgtt aaaggagaaa gatgaaacaa
     1081 agcttaaaat tcggactact tttagtgttg gctttgctca tccattgtgc aactaatgga
     1141 gcaatggaag atatgtgcaa agtttcctcc ccgacttatc ggcaggagaa atgctatgta
     1201 tcacaagatc gtccgattca ggatgcttta gaacgtcttt ataatcttta tacgactcaa
     1261 acctgtgaca tgagtcatac agacgtcgca catgttccga cagataaaag catgtttttg
     1321 ttaatcgctt atttctgtga ccattacaaa catcaaagtc cgccttaccc tgtctcatcc
     1381 cattctccta catattatta tgatcctatc tcctattata tatatgggtt aagaaagata
     1441 gtcatttagc ctacagtaca gtagactctt ttactcgtca tttattacag ttggttttat
     1501 tctccatagg gcgaatagac taattgctta tttctatata atattcaatc taaacagcta
     1561 ttgaattatg aattttacat ttttagttgt tgttctactg acagcgcttg cttttgttgg
     1621 tgtagtagta gctctttcgc gtgctatttc tccccgttca tacaatctgc aaaagtttga
     1681 agcttatgaa tgtggtatac cgacacgtgg taaatcatgg atgcagtttc gcgtaggcta
     1741 ctacctgttt gccatcctat ttcttatgtt cgatgtcgaa acagcttttc tgtttccgtg
     1801 ggcggtagtt atgcgtgaca tgggaccaca gggacttatt agtgttctct ttttctttat
     1861 cattttagtt ctgggtcttg cttatgcctg gaggaaagga gctttggaat ggaaataacc
     1921 aaaaagccaa aaataaaatc tattccgtat gatgagttta tcgacaatga atcattggaa
     1981 aagttggtca aagaacttaa tgcaggagga gccaatgttg ccctcggagt acttgacgac
     2041 tttatcaact gggggcgcag caattcactg tggccgctta cctttgcaac cagttgttgt
     2101 ggtatcgaat ttatggcact gggtgccgcg cgttatgaca tggcccgctt tgggtttgaa
     2161 gtagcacgtg ccagcccgcg tcaggctgat atgattatgg tatgcggaac aatcaccaat
     2221 aaaatggctc cggtactgaa acgactttac gaccagatgc ccgatccgaa gtatgtggtt
     2281 gctgtaggcg gatgcgctgt cagcggaggt cctttcaaga agtcctatca cgtagtaaac
     2341 ggggtggaca agattcttcc ggtagatgta tatattcccg gatgcccgcc acgtcctgaa
     2401 gcattctatt atggcatgat gcaattgcaa cgcaaagtga aaatagaaaa gttctttggt
     2461 ggagtaaaca gaaaagagaa gaaaccggat tatttaagaa atgaagaatg atgaatgatg
     2521 aatgaagaat tcgcatgcaa catcccggca gatttttcat tcttaatttt tcattcttaa
     2581 tttaatttga tttatgcaag aaatacaatt tatagctcct gcagcgttac acgacgagat
     2641 gctgcgcttg cgaaatgaaa aacagatgga ctttctcgaa agcctcaccg gtatggactg
     2701 gggagtagcc gatgagaaag acgctccgga aaaactccgc ggcttaggcg tagtctacca
     2761 tctggaatct accattacag gcgaacggat agcactaaaa acagcgacaa ccaaccgcga
     2821 gctaccggaa attccgtctg tcagcgacat ctggaagata gccgacttct acgaacgtga
     2881 agtttttgat ttttatggca tcacctttgt cggtcatcct gatatgcgcc ggctctacct
     2941 gcgcaacgat tggatcggtt atccgatgcg taaagataac gacccggaaa aggataaccc
     3001 actgtgcatg accaatgaag agacgtttga tacgactcaa gaaatagaac tgaacccgga
     3061 cggaaccatc aagaacaaag agacgaaact gttcggcgaa gaagaatatg tagtcaacat
     3121 cggtccgcag caccctgcta ctcatggtgt aatgcgcttc cgtgtttctc tggaaggtga
     3181 aattattcgt aagattgatg cgaactgcgg gtatatccac cgaggcatcg agaaaatgaa
     3241 tgaaagcctc acttaccctc aaacattggc tttgacagac cgtctggact atttgggcgc
     3301 gcatcagaac cgccatgcat tgtgtatgtg cattgaaaaa gccatgggca ttgaggtcag
     3361 tgaacgcgta cagtacatcc gtaccataat ggacgagttg caacgtatcg attctcactt
     3421 gctgttctac tcttgtcttg ctatggactt aggagcgttg acagcattct tttatggatt
     3481 ccgtgaccgc gagaaaattc tcgatatctt tgaagaaact tgcggcggac gtctgattat
     3541 gaactacaat acgattggcg gtgtacaggc tgatcttcat cctaacttcg tcaaacgagt
     3601 aaaagagttc attccatata tgagaggaat tatccacgaa tatcacgata tattcacggg
     3661 taacatcatc gcacaaagcc gtatgaaagg cgtcggtgtg ttaagccgtg aagatgccat
     3721 ctctttcggt tgtaccggag gtacaggccg tgcatcagga tgggcgtgtg acgtacgtaa
     3781 acgaatgcca tacggtgtat atgacaaagt cgatttcaaa gaaatcgttt atacggaagg
     3841 tgactgcttt gcccgttacc tggtgcgtat ggatgagatc atggaaagtc tgaacatcat
     3901 tgagcaatta atagacaata ttcccgaggg accttatcag gaaaagatga aacctatcat
     3961 ccgtgttccg gaaggcagtt actatgcagc agtagaagga agtcgtggtg aatttggtgt
     4021 cttcctggaa agtcagggtg acaaaacgcc ttaccgtctg cactaccgtg ctacgggatt
     4081 gccgcttgtt gctgcaattg acaccatttg ccggggcaca aagattgccg acttaattgc
     4141 tattggcgga acaatagatt atgtcgttcc ggatattgac agataatact taattattaa
     4201 aaatatatgt tcgactttag tatagtaaca aactggatac atgagctact gctctccatt
     4261 atgccggagg gattagccat ctttatagaa tgtgtagctg tcggcgtgtg cctcgtagca
     4321 ctgtatgcca tcctggctat catattgatc tacatggagc gtaaggtctg cggttttttc
     4381 cagtgtcgtc ttggaccgaa ccgtgttggt aaatggggtt ctatccaagt ggtctgcgac
     4441 gtgctcaaaa tgctgaccaa agaaatcttc atgccgaagg gtgccgacca tttcctttac
     4501 aatcttgctc cattcatggt gattatcgct tcattcctga ctttcgcttg tattcctttt
     4561 aataaaggtg cggcgattct ggactttaat gtgggcgtgt tcttcctgtt ggcagcttcc
     4621 agcattggag ttgtcggtat cttgctggcc ggttggggta gtaacaacaa attctctttg
     4681 atcggtgcca tgcgaagcgg tgcacagatt atcagttatg aactttctgt tggtatgagt
     4741 atcatgacaa tggtagtgct gacgggaacc atgcaatttt ctgaaatcgt agaaggacaa
     4801 gctgatggtt ggttcatctt caagggacat attcctgcgg tcattgcttt catcatctat
     4861 ctgattgccg gaaatgcaga atgtaaccgt ggcccgttcg accttcccga agcggaaagt
     4921 gagctgacag ccggatatca tacagaatac tccggtatgg gtttcggttt cttctatctg
     4981 gcagaatact tgaatctgtt tatcgtagcc agtgttgccg ccaccatctt cctgggagga
     5041 tggatgccgc tgcacattgt tggtttggat ggatttaatg ctgtaatgga ttatattccg
     5101 ggctttatct ggttcttcgc caaagcattc tttgtggtat tccttctgat gtggatcaaa
     5161 tggactttcc cacgcttgcg tatcgaccag atcttgaatc tggaatggaa atacctggtt
     5221 ccaatttcta tggtaaatct attattaatg gcatgctgcg tagctttcgg cttccacttt
     5281 tgataaatga gaattatgga atataaagat aaaaaatata cgtacttagg tggtctgatg
     5341 catggcatca gtacactggc aacgggtatg aaaaccagca tcaaggtata cttccgtaag
     5401 aaagtgaccg agcaatatcc cgaaaaccgg aaagagctga aaatgttcga ccgtttccgt
     5461 ggtacgctga atatgcccca caatgagaat aatgaacatc gctgtgtagc ttgcggactg
     5521 tgtcaaatgg cctgtccgaa cgatacaatc aaagtgacca gcgaaaccgt cgaaacagaa
     5581 gatggaaaga agaagaaaat cctggcaacc tatgaatatg atttgggtgc ctgtatgttc
     5641 tgccagctct gtgtcaatgc ttgtccgcac gatgccatca cgttcgacca gaacttcgaa
     5701 catgcagtct tcgaccgggc gaaacttgtc ctgaagttga accacgacgg tagtaaagta
     5761 atagaaaaga aaaaagaagt ttagatatgg gatcaacact tgaaacagta gtattctact
     5821 ttttggcagc atttattatt gctatgtcca tcatgacggt gactacccaa cgtatcgtac
     5881 gctcggccac ctacctgctc ttcgtgctct tcggcacggc cggcatctat tttttgctgg
     5941 gttacacctt tctgggttcc gttcagatta tggtttatgc cggtggtatc gtcgttcttt
     6001 atgtattctc catcctgttg accagtggag aaggcgaccg ggccgagaaa gcaaaacgaa
     6061 gtaaagtctt agccggactc ttcactatga ttgccggttt agccattatc ctgtttatca
     6121 cactgaagca cgatttcatg cagacagcta atttggcccc gcaagaaatt agcattcatg
     6181 ctatcgggaa cgctttatta agtagtgaca aatacggtta tgtattgcct ttcgaagccg
     6241 tcagcatatt attgctggcg tgtatcatcg gtggcatcat gattgcacgt aagagatagg
     6301 aattttaagt attaactatc aaaatagagt tcgaatatga tacacatgga atattacctg
     6361 gtagtttcta ccatcatgat gtttgcagga atctatggat tctttacccg ccgaaataca
     6421 ctggctatcc tgatttctgt agagttaatg ctgaatgcta cggacatcaa cttcgccgtg
     6481 ttcaatcgat tcctttttcc ggggggaatg gagggttatt tctttgcact cttttccatc
     6541 gccatctcgg ctgcggaaac tgcaatagct atcgccatca tgattaacat ttatcgtaat
     6601 cttcgaagca ttcaggtgcg caatctggac gagttgaagt ggtgatttgt ttctcaccaa
     6661 gaattaataa taataactca agtaattaaa taaaactgta tggaactaac aattctaata
     6721 ctccttcttc ctttcttctc ctttctcata ttgggaatcg gaggtaaatg gatgtcccac
     6781 cggacagcgg gtacaatcgg tacgctgata ctgggagcag tagcagtact atcctacgtt
     6841 acagctttcc aatatttctc cgctccacga ctggaagacg gaacattcgc cacactgatg
     6901 ccttacaact tcacgtggct tccttttaca gagaccttac acttcgattt gggcatcttg
     6961 ctcgatccta tatcggtaat gatgttgatc gtcatctcta cagtgtcact gatggtacat
     7021 atctactctt tcggttacat gaaaggagaa gtcggttttc aacgctatta cgctttccta
     7081 tccctgttta ccatgtctat gctgggattg gtcgttgcaa ccaacatctt ccagatgtac
     7141 cttttttggg agctggtggg tgtaagctct tacctgctaa tcggttttta ttatacaaaa
     7201 ccggctgcca tcgctgcttc caagaaagcg tttattgtta ctcgctttgc tgacttgggc
     7261 ttcctgatcg gtatcctgat ttacggatat tacggtggta cattcggatt cactccggat
     7321 acagtatcct tgataagcgg tggagcttct atgcttccgt tggctctcgg actgatgttt
     7381 gtcggtggtg ccggtaaaag tgccatgttc ccgttgcata tctggttgcc ggatgcaatg
     7441 gaaggtccta ctccggtcag cgcattgatt catgcggcta ccatggtagt tgccggtgta
     7501 tatctggtgg cacgtatgtt cccacttttc attgcctatg caccgaatac gttgcacatg
     7561 gttgcttggg taggtgcatt caccgcattc tatgcagcaa gtgtggcttg cgtacaatca
     7621 gatattaaac gcgtactggc tttctctacc atttcacaga ttggtttcat gatggtagct
     7681 ctgggtgttt gtacttccat ggatcctcac gaaggaggtt tgggctacat ggcttccatg
     7741 ttccacctct tcacacatgc tatgtttaag gcattgctct tcctcggtgc aggtagtatc
     7801 attcatgctg tacattctaa cgaaatgtcc gcgatgggag gtttacgcaa atatatgccg
     7861 atcactcact ggacattcct gattgcttgt cttgctattg ccggtattcc tccgttctcg
     7921 ggcttcttct cgaaagatga aattctggct gcttgcttcc aatacagccc tgtaatggga
     7981 tgggtaatga cagtaattgc tgcgatgact gctttctata tgttccgtct gtactacggt
     8041 attttctggg gcaaggaaaa caaagaactc cacgcacacc acacaccaca tgaaagtccg
     8101 ctggctatga ctttcccgct gatgttcctg gcagtagtaa cttgtggagc cggatttatt
     8161 cctttcggac acttcatcag ttcgaatggt gaatcttatt ctatccatct cgatccgtcg
     8221 gtggctatta caagcgttgt cattgcgatt atttcgattg caatcgctac atggatgtac
     8281 aagaatgcca aacaacctgt tgccgattca ttggaaaaac agttcaaagg tctgcacaag
     8341 gctgcttata accgcttcta tattgacgat atataccagt ttatcacgca taagattatc
     8401 ttccgctgca tctctactcc tatcgcatgg ttcgaccgtc atgtagtgga tggattcttt
     8461 gatttcctgg catgggcaac caacacaaca agcgacgaga tccgtggttt gcagagcggt
     8521 caggtacaac aatatgcata cgtattcctt tgcggtgcac tggcacttat cctactatta
     8581 atcttataaa gcacagaacg atatgaattt cttatcaata ttcgtactta tccccttatt
     8641 gatgctggcc ggactctggg cagcacgagg aatcaaagcc atccgagggg ttatggttac
     8701 tggcgcatcg gcacttctga ttgcctccgt cgtacttaca ttcctgtatc tgggagagcg
     8761 tagtgccgga aacacggcag aaatgctttt ccgtgcagat acgctttggt atgccccgct
     8821 tcacatatcc tattcagtag gtgttgacgg aatttcggta gccatgttgt tattgtccgc
     8881 tgtcattgtg ttcaccggta cattcgcttc ctggcgtctg caaccgctga caaaagaata
     8941 tttcctctgg ttcaccctat tgtctatggg agtattcgga ttctttatat ccgtcgattt
     9001 attcaccatg ttcatgttct acgaaatcgc attgataccg atgtacctgt tgattggtgt
     9061 atggggatca ggacgtaaag aatatgcagc catgaagctg accctcatgt tgatgggtgg
     9121 ttctgccttc ctgctgatcg gtattctcgg aatctatttt ggttcgggag caacgaccat
     9181 gaatcttctt gaaatcgcac agttgcacaa catacctttt gcacagcaat gcatctggtt
     9241 cccgctgact ttccttggtt tcggtgtatt aggtgccctt ttcccgttcc atacatggag
     9301 ccctgacggt cacgcttccg ccccgactgc cgtatctatg cttcatgccg gagtattgat
     9361 gaaactggga ggttacggat gtttccgtat cgccatgtat ctgatgccgg aagctgctaa
     9421 cgaactttca tggatattcc tgatattgac aggtatctct gtagtttacg gtgcattctc
     9481 cgcttgcgta cagaccgact tgaaatatat taatgcttat tcatccgtat ctcactgcgg
     9541 actggttctt ttcgctattc tgatgctgaa tcagacagca gcaacaggag ctatccttca
     9601 gatgctttca cacggattga tgacagcctt attctttgct cttatcggta tgatttatgg
     9661 acgtacacac acacgtgacg ttcgcgagct tgccggctta atgaaagtga tgccgttcct
     9721 tagtgtatgt tatgtaattg ccggtcttgc caacctcggt ctgccgggat taagtggttt
     9781 tattgctgaa atgactattt tcgtcggctc tttccagaac aacgaccagt tccaccgtgt
     9841 actgactatc atcgcttgtt cttcgattgt gattactgca gtctacattc tgcgtctggt
     9901 aggtaaaatt ctatacggaa cctgcaccaa caaacatcat ctcgaactga ctgatgcgac
     9961 ttgggacgaa cgtgtagccg ttatctgcct catcgtttgt gtagccggac taggtatggc
    10021 tcctttctgg gttagccaca tgattggtga aagtgtactc cccgtagtct cacaactgat
    10081 tccataacct ttaattttta atctttaata attaatttgt aaatatggat tattcacaat
    10141 ttctatatat gcgagaagag ctgtcgctca tagctgtcct actgctgcta tttctagctg
    10201 acctcttcat gagtccggat gcacacaaaa atagtgggaa agcacgcctg aacaccatgt
    10261 tgcccgttat tctgatggct atccatacgg ctatcaacct gattccggga actgctaccg
    10321 atgcattcgg tggtatgtat cactatgtac cgatgcacac agttgttaaa tcgatcctga
    10381 acgtcggtac actgattgtt ttcctgatgg cgcacgaatg gatgaaaaga gaagacactt
    10441 cattcaaaca aggagaattc tatgtgctta cactctctac cttgtttggt atgtatctca
    10501 tgatttccgc cggacatttc ctgatgttct tcatcggtct tgaaacagct tctattccga
    10561 tggcagcatt gattgccttc gataaatacc gtcacaactc tgccgaagca ggtgccaaat
    10621 acattctgac agctcttttc tccagtgcat tgctgttgtt tggtctgtcc atgatctatg
    10681 gttctgccgg gactctttat ttcgatgacc tccctgccca tatcgacgga aatccgttac
    10741 agatcatggc atttatattc ttcttcacag gaatggcatt caagttgtca ctggttccgt
    10801 tccacttatg gacagcagac gtttacgaag gcgctccgag tacagttacc gcttatttga
    10861 gtgttatatc aaaaggatcg gctgcatttg tattattggc cgtccttatc aaagtattcg
    10921 ctccaatgat taatgactgg caggaagtac tttattgggt aaccatcgct tctatcacta
    10981 ttgccaatat atttgctgtc cgtcagcaaa acctgaaacg tttgatggcg ttctccagta
    11041 tttcgcaagc gggatatatt atgttaggcg ttatcggagg cacagcacaa ggcatgacag
    11101 cattggtata ttatgtatta gtgtatgctg ccgccaacct cggagtattt gccgttatca
    11161 ctatcgtggc attacgcagt cagaaattca cgctcgaaga ttacgcagga ctttataaaa
    11221 cgaatcccaa aatcgctctt ttgatgactc tgtctctgtt ctcattggca ggcatccctc
    11281 cgtttgccgg attcttctct aagttcttta tcttcatggc tgctttcgat gcaggtttcc
    11341 acttgctggt attcatcgca ttggtaaata cagtgatttc attatactac tatctgttga
    11401 ttgtaaaagc aatgtacatc actccttccg acaacccgat tcctactttc cgcagcgacc
    11461 gttgcacaaa atggggactg gcactttgca cattgggtat catcggactg ggtattgcaa
    11521 gtatcgtata tcaatccatc gataaactat cgttcggaat ttaaacgaac ttcctttata
    11581 acgtaagaaa cggtcttggt ttcatgtcag tatcaatcga catcaaaacc aagaccgttt
    11641 cttctatata aaagccactt ttattaatga ggaaggaaga tattcacctg cctcattacc
    11701 actctaccgg gcacagccca cctcttccgt cacaatcact ccgggaatag taaaccaaaa
    11761 ccttgatcct tttccttttt cagaatcaac gtcaatccgc ccacctaatt gttcaacgat
    11821 gctctgacag atagaaagtc ccaatcctgt accgtgtaca aaagaattaa gcttcacgaa
    11881 acgctcaaaa atatgtggca attgctcttt ctcaataccg attcccgtat cttcgacata
    11941 aaactccaat tctccgtctt ttagtttata ccccacatga atacttcctt cagaggtaaa
    12001 cttcattgca ttattaacaa agttagagat cacctgatgt atacgattac ggtcactaat
    12061 gacatgacaa accggaaggt gattatcaag taccagttcc acctctcctt tcgctttcat
    12121 gcgcatagag cggacaatat cttcacacag cagatataca tctacatctc cattagtaaa
    12181 ttcaaacgta ccagcctcaa tctttgataa atcaagtata tccgaaatta gttgcaacaa
    12241 gagatcatta ttctcacgta caatcttaat atattcctga cgttcttcca actcttctgt
    12301 ttccaccaac aaatcggaga aaccgacaat ggcattcagc ggcgtacgga tttcatgact
    12361 catattggca aggaaagcac ttttcaaacg atccatcatc tccgctttat cacgcgcctg
    12421 aatcagttcg gcttcagttt ctttcaattc tgtaatatca taattgatac cgatgatttc
    12481 tatttcattt tcctccgg
//
