LOCUS       c00200_gnlPro..         9720 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JCOLNFCF_200.
ACCESSION   c00200_gnlPro..
VERSION     c00200_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:35:13
            Original ID  :: gnl|Prokka|JCOLNFCF_200
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9720
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9720
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2808:7668]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2809..7668
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..9720
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9720
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..202
                     /locus_tag="ctg200_1"
                     /transl_table=11
                     /translation="TLNKLPENYRTVFIKSFFEGKTHTEIAEEMNLSVKSINRYKQKTM
                     ELLRNELKEYMPLLLLLFLRA"
     CDS             complement(575..1690)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 53.2; E-value: 6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg200_2"
                     /sec_met_domain="AMP-binding (E-value: 8.7e-18, bitscore:
                     53.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQQQRLLLEGKEYTFEDISQLIAGGAEAHSSAYWDLYLFLN
                     EWFNGSPVITVHTSGSTGIPKELMVRKDQMMQSARLTCEFLNLKKGESALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKEPLRFVAMVPLQVYNTMQVPEEKERLKQTD
                     ILIIGGGAVDEALETEINHLPTAVYSTYGMTETLSHIALRRLNGASASEHYYPFPSVKL
                     SLSAENTLIIDAPLVCDETLQTNDIARIYPDGSFMILGRKDNVINSGGIKIQAEEMEKL
                     LRPFIPVSFVITSVPDQRLGQAVTLLLADQPDTEEIGNKLHEILEPYYRPKHILTIESI
                     PQTENGKINRAECRILAKQMLMTFYPHTLTP"
     CDS             complement(1722..2747)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg200_3"
                     /sec_met_domain="MR_MLE_C (E-value: 3.1e-30, bitscore:
                     94.6, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRLLHFKQPAGTSRGIYTTRKVWYLHFTSPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILKRICRQVEKEQGMWDKDVLCQYPSILFGLETAIWHFF
                     AGSWALSDTAFSRGEVGIPINGLIWMGDFDHMLSQIEKKMEAGFRCVKLKIGAIDFEKE
                     LALLRHIRTHFSSKEIELRVDANGAFSPGDAMEKLKRLSEFDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGCNTLEEKKKLLATIRPQYIIIKPSLHGGICGGDEWIMEAEK
                     QHIGWWITSALESNIGLNAIAHWCATFNNPLPQGLGTGMLFTDNIEVPLEIRKDCLWFC
                     K"
     CDS             complement(2809..3633)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_4"
                     /sec_met_domain="ECH_1 (E-value: 8.2e-83, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             complement(3637..5304)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-08, bitscore:
                     21.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYAVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVVISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINVPISEPLFQFTVDALPEVRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMN
                     LIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKIDQMVPELLIT
                     YGGHVVSKRLKKFLRQHPPKEHWHVSPDGEVVDLYGSLTTVIEMDPFEFLEKIASLLDN
                     RTPDYPRVWENYCKIIPEPEFAYSEMLAVGTLLKALPESCALHLANSSVVRYAQLYSIP
                     STIEVCCNRGTSGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNINVRSNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQAQNDEELTEAM
                     KTFTQPETMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             complement(5324..6439)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg200_6"
                     /sec_met_domain="Chorismate_bind (E-value: 1.5e-57,
                     bitscore: 184.3, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVRL
                     IYDLKELNGQRGFVIAPFQVSETCPVVLIQPDQWGQPLPIDNDTAEEREVALRMQGQES
                     FLTSSTEEYASCFHTFINALRDNTFDKLVLSRHLTIDKVSGFSPLSIFRAACRRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWHTVALAGTQPLQDGRLPQVWDEKNRKEQDYV
                     ASYIRRQLLSLGIHSTENGPYPAYAGALSHLKTDFRFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYRFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMHIKDEQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIATPPLKS"
     CDS             complement(6436..7668)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_7"
                     /sec_met_domain="HBT (E-value: 1.4e-18, bitscore: 56.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNG
                     FALFTYHDDTIITDSPENEHIQNEARLNDLQIIKEEEFSAAVDFAPCKCMLVSDDEEAL
                     LGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLGMKREEVIAVGDGV
                     CDVTMIQLAGLGIAMGHSQDSVKACADYVTASNEEDGVAVAVEKAIISEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(7752..8114)
                     /locus_tag="ctg200_8"
                     /transl_table=11
                     /translation="MIQVRIKRVYEDFSETDGYRVLVDKLWPRGMKKEWLKYDYWAKDI
                     TPSPTLRKWFHEDIPGHWGDFVTQYQKELDASPSMADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMRLRE"
     CDS             complement(8179..9720)
                     /locus_tag="ctg200_9"
                     /transl_table=11
                     /translation="RNMYMNKLAFMYARKSYLLDSISQREPKHMLKMTVYLAELSSIMS
                     KYNESMHYALSGIMQAQKLKDREAEARLLFCIGENNWRLSLKDEAYNYFGRTIELLRGS
                     KDMREMMLLSYYYGAEMGFLMTDSRIDEALALAYEREKLLKKLEKVPEVPEGYIDGQYS
                     YLYAKLAYISYLEKKYTQAEGYYQKYLAIKESHTPDGKMYSIPYLILSKQYETVIDNCK
                     DFKELLRTQRDTLNAQYLTILNKEVQAYLGLNRYKEAAEIRETIIAITDSINSTDRKNA
                     ALELNAMYGASEKEEYIAEQASQLKIRNVSLCFLACIVVLTLFILWRLWRFNHIIEYKN
                     RMLAKLINEKFANKKDGNQLLEVYEEQEVSSELEPELISPEEQDELLDETDKESGEEEE
                     NKKIFQELNHTVVQKQLYLSPELSREDLAQIVHLNNARFARMIRECTGTNFNGYINGLR
                     INYAIKLMKKYPNYTIRAIADESGFNSAPILYNLFKKKTGMTPYEFKKAQDTLRN"
ORIGIN
        1 gacattaaac aaacttcccg aaaactatcg aacggtcttt attaaaagtt tctttgaagg
       61 caaaactcat acagagattg cagaagagat gaatcttagc gtgaagtcta tcaatcgata
      121 taaacaaaaa acgatggaac ttttacgtaa tgaattaaag gagtatatgc cactattact
      181 cttgttattt cttcgtgcat aatctacatc ctcatgttct cttcctggta tatgcctttc
      241 ttttgaaaaa cagtcgtact ctatatatgt attagtcctg ttgtttatat cactctgctt
      301 aatagttagc aggggcttac ttgtgtggac agataagcta tcagttgtga acaaatccgt
      361 ttacggttgt aaacagattt gttcacatgg gtgagccctt gtaaaacatt agagcttaac
      421 aaaagaatac ctaagtatca atgtatgata tatagggaaa tatagtataa attagctggg
      481 aacaagacga gccagggtga gggtaacttt ttaccctcac cctggcctca cctctaccct
      541 cacacttgaa acaccgatga ataaagggat tgaatcaagg tgtgagggtg tgagggtaaa
      601 acgtcatcaa catttgtttg gctaagatgc gacactctgc ccggtttatt tttccgttct
      661 ctgtttgcgg aatggattct attgtcaata tatgcttggg acgataataa ggttccagta
      721 tttcatgtag tttatttccg atttcttctg tgtcgggctg atctgccaat aataaagtga
      781 cagcctgccc taagcgctga tccggaactg aagtaatgac aaaggacaca ggaataaacg
      841 ggcggagcaa cttctccatc tcctctgctt gaatcttaat tcctccactg ttaatcacat
      901 tgtctttccg gcctagaatc ataaaacttc catcgggata gatacgtgca atgtcattgg
      961 tctgcaatgt ttcgtcacat accaaagggg catcaatgat taatgtattc tctgcggata
     1021 aagacaattt tactgaagga aatggataat aatgttctga agccgatgct ccgttcagac
     1081 gacgaagggc aatatgcgac aaagtttcag tcatgccata agtggagtaa acggcagtcg
     1141 gaagatggtt tatctccgtt tccagagcct catcaacagc tccgcctcct ataatcagaa
     1201 tatccgtttg ttttaatcgc tctttttctt cgggaacctg catcgtgtta taaacttgca
     1261 atgggaccat tgccacaaat ctcaaaggtt cttttatatc cgccaacgga tgaccggaag
     1321 caggacgaac aatcaggttc aaacctgcaa ccaatgaacg tacgaccacc atcattgcac
     1381 cgatataacg aagattcata cataataatg ccgactcacc tttcttcaaa ttcagaaatt
     1441 cacaagtcag acgcgcactt tgcatcattt gatccttgcg taccatcagt tctttaggta
     1501 tacccgtgga acccgatgta tgaaccgtga tgacaggaga gccattaaac cattcgttca
     1561 ggaaaagata taaatcccaa taagcagaag aatgagcttc tgctcctcct gctatcaatt
     1621 ggcttatatc ttcaaaagtg tattcttttc cttccagtag caagcgctgt tgttgtcgat
     1681 cgaatatcat ctgaatatcc tttaaatacc actaaatacc atcatttaca aaaccacagg
     1741 caatcttttc tgatttcaag aggcacttct atattgtcag taaagagcat acccgttccc
     1801 aatccttgtg gcaacggatt attgaatgtt gcacaccaat gggcgatagc gttcaaacca
     1861 atgttggact ctaaagcgga agtgatccac cagccgatat gttgcttttc cgcttccata
     1921 atccattcat cccctccgca tattcctccg tggagagatg gtttaatgat gatatattgc
     1981 ggacggatgg ttgccagcag tttctttttt tcttccagcg tgttgcatcc tatcagctct
     2041 tcatccaatg ctatcggcaa cggagattca gaagtgagcc gggccatttc ctcccattgt
     2101 ccggcacgga tcggctgttc gatagaatgt aaatcaaatt ctgacagacg tttcagtttt
     2161 tccattgcat cacccggaga gaaagcaccg tttgcatcta cacgcaactc tatttcttta
     2221 gaagagaaat gggtacgaat atgacgtaac aacgccaatt ctttttcaaa atcgatagca
     2281 ccaatcttta gtttgacaca acggaatccg gcttccatct ttttctcgat ttgggataac
     2341 atgtgatcaa aatctcccat ccagatcagg ccgttgattg gaatccctac ctctccacgt
     2401 gaaaaagccg tatcggataa agcccaactc cctgcaaaga aatgccagat agccgtttcc
     2461 aaaccaaata agatggaagg atattggcat aaaacatcct tatcccacat tccttgttct
     2521 ttctctactt gccgacaaat tctttttaat atatcttcat aatcagggag atcatcacaa
     2581 cttaaagcgg gcaaaggcgc gcactctcca attcccactc tacccggaaa gtcaggagaa
     2641 gtaaagtgaa gataccagac ttttcgggta gtatatattc cccgggaagt tcccgcgggt
     2701 tgcttgaaat gaagcaaccg gggaataata tctatcttac aatccataat gaatatcttt
     2761 tcaatctgct aattactgca caatcagtct ttcattagcc tatcattttt aagggaattt
     2821 cggatattgt ttgaagttcg gtttacgttt ctccaagaac gcattcttgc cttcctgtgc
     2881 ttcatccgtc aggtaataaa gtaatgttgc gtcacctgcc aactcctgaa tacctgcctg
     2941 accatccagt tcggcattca atcccgcttt aatcatgcgc aaagccaacg gactaagcaa
     3001 catcatttct tccgcccact gcacgtattc atcttccagt tgttccaaag gtactacctt
     3061 attcaccaat cccatatcca atgcttcctg tgcattatac ttccggcaaa ggaaccaaat
     3121 ttcacgtgct ttcttctgcc ctaccacgcg tgccagataa gatgcaccga atccggcatc
     3181 aaagctaccc acgcgaggac ctgtctgacc gaaaatggca ttttccgaag caatggataa
     3241 atcacatact acatggagca catgtccgcc accaatggca aagccgttca cggcagcaat
     3301 cacaggtttc ggaatactac gaatttgctt ttgtacatcc aatacgctca aacgaggcac
     3361 accgtctttc ccgatatatc cgccacgtcc tttcacattc tggtcgcctc ccgaacagaa
     3421 tgccttatca ccggctccgg taattacaat cacatcaata tccgcttctt cacggcaaat
     3481 gcgcaatgca tcactcattt cggcagtggt agtcggggta aatgcattcc gataacgttc
     3541 acggttgatc gtgatacggg caattccatt ataataatca aaaagaatat cgtcgtattc
     3601 tctgatggtt gtccactctc tttgtgttgg cataatttat ttttgtttta attgatgata
     3661 ataattcttc aacatacgtg catccttgtt tttgttggta aacacttcca gaagcacagg
     3721 ttgttccata gtttccggct gggtgaaagt tttcattgct tcagtcagct cttcatcatt
     3781 ttgcgcttgt agataaagga agccacgttc ctctgcccag cctttagctg acgttttatg
     3841 gactgctgca ataaatttat gtgaggtgcc cgacatatcc aatcccggta aagtatggaa
     3901 aatctctcct cctccgttat ttaataaaag gatacgcagg ttggaacgga cgttgatatt
     3961 ccacaacgca ttcatatcat agaagaaact tagatctccg atagctatga aattcagttt
     4021 gtcggaagct gccgcataac cgacagcggt agacaacgac ccttcaatac cactcgttcc
     4081 ccgattgcaa caaacttcaa tcgtggaagg gatcgaatat agttgtgcat aacgaactac
     4141 cgaactgttt gccagatgca atgcgcagga ctccggcaaa gctttcaata atgtaccgac
     4201 agccaacatt tccgaataag caaactccgg ttcgggaata atcttacaat aattctccca
     4261 tacacgggga tagtcaggag tccggttatc cagcaggctg gcgatcttct ccagaaactc
     4321 gaacgggtcc atttcgatca ccgtagttaa tgagccgtac aaatcaacca cctcaccgtc
     4381 cggcgatacg tgccaatgtt ctttaggcgg atgctgacgg agaaacttct tcaatcgttt
     4441 ggaaaccaca tgtcctccgt aagtaatcag caattcgggc accatctggt ctatcttctc
     4501 ttcgggcatg gcataaagtg ccgcatcgaa attctttacc ggaataccgg gaactgtctg
     4561 attgccgata tgttccgtca accaggcaaa atgtttatat aataacttga tatatctttt
     4621 ttcaaacagg tagataaggt tcatctggcc gatgataatc atgcgcttct gatatttatt
     4681 catccggtcg accagatcat tataatcacg gtcatagacg ttcaatccct gataacgggt
     4741 tatcacacgt acttccggga gtgcatctac cgtgaattga aacagcggtt cggaaatagg
     4801 aacattgata tgcaccggcc cttttccatg atgattcgtc tccagcaaag cttcattcac
     4861 caggcgatta caataccatt catcttcttc cgtatgaatc tccggaagat tgaccgactt
     4921 ctttaccagc gtttgaaaca cacccggttg cggcactgtc tgtccatcca tctgtccgat
     4981 ccaggcagcg ggacggtctg ctgaaatgac aactaaagga acattctgat aaaatgcttc
     5041 cgctacagcc ggatgaagat ttaataatgc agtaccggaa gtgcagcaca cagcagcggg
     5101 cttaccacca ttcaacgcaa gaccaatagc aaaataaccg gcactccgtt catccgtcac
     5161 tgcataacag gtgaagttcg gatgattaga caaagtatgt acgatgggcg tattacgact
     5221 acccggacac aacacaacct tagtaatccc gtgcgcctcg agcaacgcaa ccaactggag
     5281 tatgttcttc ttgtctgtat acatgatgat aattattagt agtttatgat tttaaaggag
     5341 gcgttgcaat cagccgtttg atggtttgca acttcttttc cgtttccagc cattcgtcat
     5401 tcaattccga agaagccagt agtccaccgc cggcataaag agtcagttgt tcatctttaa
     5461 tatgcataca gcgcagattc acatagatgt cagttcgccc ttccgggtcc agccaaccga
     5521 taaaaccgga ataataacgg cggtcgtaac cttcgttctg caatataaac cgataggctt
     5581 cttctttcgg taaaccgcat acagcaggcg ttggatgcaa cactttcaag agatctccca
     5641 aacctttgtt atctttcaaa gaaaaccgga aatctgtttt caaatgtgac aaagcacctg
     5701 cataagccgg ataaggcccg ttctccgtag aatgaatgcc caacgatagg agttggcgac
     5761 gaatataaga agcgacataa tcctgctctt tccggttctt ttcatcccac acttgcggca
     5821 gtctgccatc ttgtaaaggc tgcgttccgg ctaacgcaac cgtatgccat tcgtcttttt
     5881 cacctgataa aatgatttca ggagtgcttc ccagccagat acccgtctgc ggagtgtagc
     5941 acaagtatat atatgaatga atataacgcc tgcacgctgc acgaaatata gacaaaggag
     6001 aaaaaccgga tactttatca atagtaagat gacgtgaaag tactaattta tcaaaagtat
     6061 tatcacgcaa agcatttata aaggtatgaa agcaggaggc atattcctcc gtagaagaag
     6121 tcaggaacga ttcttgtcct tgcatccgca aagcgacttc ccgttcttct gccgtatcat
     6181 tgtcaatcgg caaaggttgc ccccactgat cgggttgaat caatacgaca ggacacgtct
     6241 cactcacctg aaacggagca attacaaatc ctctctgtcc attcagttct ttcaaatcgt
     6301 atatcaaacg gaccgctcct tccgcctgtg tcaacagacg gggaactttc tccccgggaa
     6361 tgcggtaaac agcaaacggc tgcttccgct gaataaatgc atcaatagtt gtcaaattac
     6421 ttatttcttc gtcggtcatc tctttttcat cacactgttg actacccgta tggaagacac
     6481 tagtttgttt gttgaagtaa acacgtctac attccataca tgggaggaac gtcccttatg
     6541 tacaactgtt cctactgcac gcactgtatc tccttcatgt gcagaagata tgtggtttcc
     6601 actgacctgc attcctacta caatctcgtc cggctggcaa agaatcattg aaccgagtcc
     6661 ggcaactgtt tccgccaatg caagagtagc cccgccatgc aaaatgccaa aaggctgacg
     6721 ggtacgatgg tctaccggca ttgttgcttc cacacggtct tcgtcggcat aggtatattg
     6781 aattcccaag tttcccatca atgcgtggcg tgcctgcgca ttcagttggt caaggggaat
     6841 ttcggctgca cgcacttcgg atatgatagc cttctccact gcaacggcca ctccgtcttc
     6901 ctcattcgaa gcagtcacat aatcggcaca ggctttcacc gagtcttgtg aatgtcccat
     6961 agctatgccc agccccgcca attgaatcat tgttacgtca cacacaccgt cgcccacagc
     7021 aatcacttcc tcacgcttca tacctagcac ctccagcaaa gcacccaaag aattggcttt
     7081 gtcgatggcg cagggaacta cttccagaaa atagggctcc gaacggaata cgtccaacgc
     7141 cccattcagt cgtctcttcc agtgatcttc caaaccaagc aatgcttctt cgtcatcgct
     7201 caccagcata cacttacaag gagcaaaatc aacggcagca gaaaattctt cttctttgat
     7261 tatttgcagg tcattcaacc gggcttcatt ttggatatgt tcattttcag gagaatccgt
     7321 tatgatcgta tcatcatgat aagtgaataa agcaaaaccg tttttacggg ctttcttttc
     7381 cagatacggc aacatttcgg gattaatccg acgttcaaac agaatttctc cgttttgtgc
     7441 attgataatc tgacagccat tataggaaag gataaaacct ccatagtttc caagttcgag
     7501 catcttggcc agcggcatca ggccataagt cggtctgccg gacgccagca caatacgtac
     7561 tcccatttgc tgaaccttca acagggcagc caatgtacgt ttactaattt ctttcgcatc
     7621 attgaggagt gttccgtcta catcaagaac caataattta tacttcatga ttacacgatt
     7681 ttgatttaga ttacaaaggt aggaaattga gtgaacgaca gaaagcgtaa acagataaaa
     7741 ttactttaat ttcactctct caaacgcatt tccagataat cgcgaagaat tcgggcgtga
     7801 ttatacaccg gttcttttga agcataaagt agtgttatca ccggatgtgg tttgataaga
     7861 gtcagaaaat cagccattga tggagaagca tccagctctt tttgatactg cgtgacaaaa
     7921 tctccccaat gtccgggaat atcttcatga aaccatttac gtaatgtagg ggatggtgtt
     7981 atgtcttttg cccaataatc gtatttcaac cattctttct tcattccgcg tggccataat
     8041 ttatctacca acacccggta tccatctgtt tctgaaaaat cttcgtaaac cctctttatc
     8101 cttacctgta tcatttccat taatatttag ttatcaatag ataaaccggg aaaaacgaaa
     8161 attgtttagt agaactattt aattcctcaa tgtgtcctgc gcttttttaa attcataagg
     8221 agtcattccc gtctttttct taaaaaggtt atataatatc ggggcactat taaatccgga
     8281 ttcatcagcg atggcacgta tggtatagtt aggatatttt ttcattagct tgatcgcata
     8341 attaatgcgc agtccgttga tgtacccatt gaaattagtt ccggtgcatt ctcttatcat
     8401 ccgggcaaag cgtgcattat tcagatgtac aatctgcgcc aaatcttctc ttgagagctc
     8461 tggagaaaga tatagctgtt tttgaacgac tgtatgattt aattcctgga atattttctt
     8521 gttctcttct tcttccccac tttctttgtc tgtttcgtcc aaaagttcat cctgttcttc
     8581 aggagaaatc aattccggtt ccaattctga tgaaacctcc tgttcctcgt acacttccaa
     8641 taactgatta ccatcttttt tattggcaaa tttctcgttt atcagtttgg caagcatcct
     8701 gtttttatac tcgattatat ggttgaaacg ccacaaacgc caaagtataa acagggtcag
     8761 cactacaata cacgccaaaa agcagagtga aacattcctt atttttagct gtgaggcttg
     8821 ctcggcgatg tattcttctt tttcggaagc accgtacatc gcgttcaatt ctaatgcagc
     8881 atttttcctg tcggtactgt taatgctatc cgttattgca atgatggttt cacgtatttc
     8941 tgcggcttct ttataacgat tcagccccag atatgcctgg acttccttat taagtatagt
     9001 taaatattga gcgttcaagg tatcccgctg tgttctcaac aattctttaa agtccttaca
     9061 gttgtctatt actgtctcat attgtttgga aagaatcaaa taaggaatcg aatacatctt
     9121 gccatccgga gtatgagatt cttttattgc cagatatttt tgataatatc cttctgcttg
     9181 cgtatatttc ttttctaaat aagaaatata ggccaatttt gcatataaat agctatattg
     9241 accatcaatg tagccttcgg gaacctccgg tactttctct aattttttaa gaagtttttc
     9301 acgttcataa gcaagagcca aagcttcatc aatacgggaa tctgtcatta aaaatcccat
     9361 ctctgctcca taataatagg aaagcagcat catttctctc atatcctttg acccacgcag
     9421 taattcaatc gtacgaccaa aataattata cgcctcatct ttcaatgaca gcctccaatt
     9481 attctctcct atgcaaaaaa gcaatctagc ttccgcctct ctgtccttca gtttttgagc
     9541 ctgcataatt ccactaagag cataatgcat gctctcatta tatttactca ttatggatga
     9601 aagttcagct aaataaaccg tcatcttcaa catgtgctta ggttctcttt gagagatgga
     9661 atcaagcaag tacgacttcc ttgcatacat aaaagctagt ttattcatat acatattacg
//
