LOCUS       c00055_gnlPro..        12960 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKBIDGBN_55.
ACCESSION   c00055_gnlPro..
VERSION     c00055_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:13:43
            Original ID  :: gnl|Prokka|BKBIDGBN_55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 534
            Orig. end    :: 13494
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12960
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10534:13378]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12844
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..12960
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12960
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             560..1237
                     /locus_tag="ctg55_2"
                     /transl_table=11
                     /translation="MSNYYSSNPKLYVGIDCIIFGFNEGELNLLLLKRNFEPAMGEWSL
                     MGGFVQEDESVDDAAKRVLNELTGLEDVYMEQVQAFGAIDRDPGERVVSIVYYALININ
                     EYDKESVQQHNAFWVNINELPALIFDHPQMVEKARKLMQQKASTEPIGFNLLPKLFTLS
                     QLQSLYEAIYGESIDKRNFRKRIAEMEKKEKTDKIDKTGSKRGAALYQFNEKAYRKAPK
                     FKL"
     CDS             1280..1966
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_3"
                     /sec_met_domain="Aldolase_II (E-value: 1.1e-53, bitscore:
                     171.8, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEALKDKVFHANLELVKHGLVIFTWGNVSGIDRESGLVVIKPSG
                     VSYDEMKAEDMVVVNLDGKVVEGRLKPSSDTPTHLVLYKAFPEIGGVVHTHSTYATAWA
                     QAGCDIPNIGTTHADYFHDAIPCTADMTKEEVEGAYELETGNVIVKRFEGLNPVHTPGV
                     LVKNHGPFSWGKDAHEAVHNAVVMEQVAKMASIAYAVNPNLTMNPLLIEKHFSRKHGPN
                     AYYGQK"
     CDS             2005..3513
                     /locus_tag="ctg55_4"
                     /transl_table=11
                     /translation="MNAFEQYEVWFVTGAQLLYGGDAVIAVDAHSNEMVKGLNDSEKLP
                     VKVVYKGTVNSSKEVTAAFKAANNDEKCIGVITWMHTFSPAKMWIHGLQELKKPLLHFH
                     TQFNKEIPWETMDMDFMNLNQSAHGDREFGHIVTRMRKNRKVVVGHWQDEKAQNQIAAW
                     MRVAAAWADAQDMLIIRFGDQMNNVAVTDGDKVSAEQVLGYHVDYYPINDVMTYYNAVS
                     DEDVKALVAEYFKLYDHAPELEDARTEAYTKVWNSAKAEIAIRRVLKDTGAKGFTTNFN
                     DLGDFDQIPGLASQRLMAEGYGFGAEGDWKTAALYRTTWVMSQGMPKGCSFLEDYTLNF
                     DGEKSAILQAHMLEVCPLIAEQKPKLEVHRLSIGIDSETARLVFTSKQGEGVAATIVDL
                     GNRFRLIVNKVECIKSKPLPKLPVASALWIPMPNLEVGAAAWILAGGTHHTSFSYDLTV
                     EYWEDFAEMAGIEMVVIDENTTISEFKKELRMNEVYYMLNKALC"
     CDS             3638..5236
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_5"
                     /sec_met_domain="FGGY_C (E-value: 1.2e-29, bitscore: 93.4,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.3e-19, bitscore: 59.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLDAKSTIEAGKAILGIELGSTRIKAVLIDQENKPIAQGSHTWE
                     NQLVDGLWTYSVEAVWYGLQDCYADLRTNVKSLYDTEIETLAAIGVSAMMHGYMAFNEK
                     EEILVPFRTWRNTNTSQAAAALSELFVYNIPLRWSISHLYQAILDNEEHVPSINYLTTL
                     AGFVHWQITGQKVLGIGDASGMLPIDPITKNYSSEMVDKFDKLIAPKGYDWKLRDILPK
                     VLSAGENAGFLTPEGASRLDVSGHLKAGIPVCPPEGDAGTGMVATNAVKQRTGNVSAGT
                     SSFSMIVLEKELSKPYEMIDMVTTPDGSLVAMVHCNNCTSDLNAWINIFKEYQELMGIP
                     VDMDEIYGKLYNHALTGNADCGGLISYNYISGEPITGLAAGRPLFVRSANDKFNLANFM
                     RTHLYASVGVLKIGNDILFNEEKIRVDRITGHGGLFKTKGVGQRILAAAINSPISVMET
                     AGEGGAWGIALLASYLANNGNDQSLADFLDKHVFTGNAGIEISPTAEDVSGFNTYIESY
                     KAGLPIEEAAVRFKN"
     CDS             5260..6804
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MNTKLFISSIFLSTSLSLFAQKSATITLHTDQSGQIIPKEIYGQF
                     AEHLGTCIYGGLWVGENSDIPNINGYRTDVFNALKELRVPVLRWPGGCFADEYHWMDGI
                     GPKENRPKMVNNNWGGTIEDNSFGTHEFLNLCEMLGCEPYISGNVGSGTVEELAKWVEY
                     MTSEGDSPMARLRRQNGRDKAWKVKYLGVGNESWGCGGSMRPEYYADLYRRYSTYCRNY
                     DGNSLFKIASGASDYDYNWTKVLMDRVGGRMHGLSLHYYTVSGWNGSKGAATRFSKDDY
                     YWTLGKCREIEDVIKKHCTIMDKYDPQKNVALMLDEWGTWWDTEPGTNPGHLYQQNTLR
                     DAFVASLSFDIFHKYTDRLKMANIAQIVNVLQSMILTSGKNMVLTPTYYVFKMYNVHQD
                     ATYIPLELNCDMMDVRDNRRIPMVSATASKDPNGKIHISMSNVDADNAQEVTINLSGTK
                     AKKAVGEILTSTNLTDYNSFENPDNVKPVPFKEVKINKDILKIKLPAKSIVTIELQ"
     CDS             6995..9004
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_7"
                     /sec_met_domain="Transket_pyr (E-value: 1.2e-35, bitscore:
                     112.7, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 4.1e-94,
                     bitscore: 305.1, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFS
                     EFLVYDPENPAWEGRDRFFLDPGHMSPMLYSTLALTGKFTLDELKEFRQWGSPTPGHPE
                     RDIMRGIENTSGPLGQGHTFAVGAAIAAKFMKARFEEVMPQTIYAYISDGGIQEEISQG
                     SGRIAGALGLDNLIMFYDANDIQLSTETKDVTIEDTGKKYEAWGWKVIKINGNDPDAIR
                     GALNEAKAEKECPTLIIGHTVMGKGARKADGSSYEADCATHGAPLGGDAYINTIKNLGG
                     DPTNPFVIFPEVAELYAKRATELKKIMAEKYAAKAVWAKANPEKAAKLEMFFSGKAPEV
                     NWAAIEQKAGVATRAASATVLSALATQVENMIVASADLSNSDKTDGFLKKTHAFKKGDF
                     SGAFFQAGVAELTMACCCIGMALHGGVIPACGTFFVFSDYMKPAVRMAALMEVPVKFIW
                     THDAFRVGEDGPTHEPVEQEAQIRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMEN
                     TTTPTGLIFSRQNIANLPEGNDYEQAAKGAYIVAGSDENPNIILVASGSEVATLVAGTE
                     LLRKDGIKVRIVSVPSEGLFRSQAPGYQEGIIPCGAKVFGLTAGLPVTLQGLVGPRGKV
                     WGLESFGFSAPYKVLDEKLGFTAENVYKQVKAML"
     CDS             9096..9533
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MKTIGICSDHAGFELKEYVRGWLEAKGWAYKDFGTYSTESCDYPD
                     FAHPLALAVEAGECYPGIAICGSGEGISITLNKHQGIRAALCWTAEIAHLARQHNDANV
                     LVMPGRFISTEEADMIMREFFSTPFEGGRHQRRVDKIPVHL"
     CDS             9709..9984
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MERLNTIKELINQGNVEQAIQQLDEILQTDFPGKDEAYYLRGNAY
                     RKQGNWQQALNNYQYAIDLNPESPAQHAYQMAMDILNFYNKDMYNQ"
     CDS             10001..10228
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_10"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-13, bitscore: 41.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.3e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.3e-09, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLNVIALTKEVNVKGYNYAH
                     QILEDTCNGCASCATVCPDGCISVYKIKVE"
     CDS             10248..11333
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_11"
                     /sec_met_domain="PFOR_II (E-value: 5.3e-29, bitscore: 90.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.9e-49, bitscore: 158.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGLAFELAFK
                     YRNPAIILADGVIGQMMEKVVLPVQKPRRTDAEVIEQCPWATTGRTNGRKPNVITSLEL
                     KPEEMEKNNIRFQAKYKQIEENEVRFEEIHCDDADYLIVAFGSMARIGQKAMELAREEG
                     IKVGMLRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVDALKEKLIKK"
     CDS             11330..11503
                     /locus_tag="ctg55_12"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMVLALAAIIIYFAAKDDFKLFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             11515..12276
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-26, bitscore:
                     83.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEDIIKPENLVAKKPTLMNDNPMHYCPGCSHGVVHKLVAEVIE
                     EMGLEDKAIGISPVGCAVFIYNYIDIDWQEAAHGRAPALATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTSTSPYGRDVHLH
                     GYPLKMADIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMAGKGSNLVEIVSTC
                     NSGWKMSPAKSNEWMVENMFPFYPLGDLKDK"
     CDS             12299..12844
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_14"
                     /sec_met_domain="POR (E-value: 1.2e-36, bitscore: 116.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDEKISSPILSKYDAAIILNQPSLEKFESKVKPGGVLIYDGYGIINPPTR
                     KDIHVYRINAMDAANEMNNAKAFNMIVLGGLLKIKPMVTLDSVLRGLKKTLPERHHHLI
                     PMNEEAIKKGMELIQEMK"
ORIGIN
        1 ttgtgatatt gggtatactc tggattccca ttatgcgcag tgtaggcgat gtactttaca
       61 cctacttaca agatgtacaa tctgtattag caccaggcat tgccgcagcc ttcctcttgg
      121 ggatctgctg gaaacgcacc tctgcacaag gcggtatgtg gggactgatt gccggaatga
      181 ttatcggttt aacccgtctg ggggcaaaag tatattacag caatgtagga gatgtgtcaa
      241 gcagtacctt caagtatctg ttctatgata tgaactggct gtttttctgc ggatggatgt
      301 tcttgttctg catcgtagtg gttatcgcag tcagcatgtt tacagctgcc ccaagcgctg
      361 aaaagattca agggctggta ttcggaactt caactcctga acaaaaagca gctacacgtg
      421 cgagttggaa taaatgggat atcattcata cccttatcat cctgggtatt actgctgctt
      481 tttattggta tttctggtaa atcggtatgt tgctatgata tatatccatg cagcataccc
      541 cttaaacaaa aattaagata tgagtaatta ctatagttca aatccgaaac tttatgtagg
      601 tatcgactgc attattttcg gtttcaatga aggagaattg aacctgctgt tgctgaagcg
      661 taacttcgaa ccggcaatgg gcgaatggtc gctgatgggt ggattcgtgc aggaagacga
      721 aagcgtggat gatgcagcca aacgagtcct gaatgaacta accggactgg aagatgtata
      781 tatggaacaa gtccaagctt tcggagccat agatcgtgac ccaggagaac gcgtagtctc
      841 cattgtttac tatgcgctca tcaacatcaa cgaatacgac aaagaatccg tacagcaaca
      901 caatgctttc tgggtaaata tcaatgaact gccagcgcta atctttgatc atccgcaaat
      961 ggtggagaaa gctcggaagt tgatgcaaca aaaagcgtcc accgaaccaa tcggctttaa
     1021 tctactacct aaactgttca cgctgtcaca actgcaaagc ttatacgaag ctatatacgg
     1081 cgagagcatt gacaaacgga acttccgaaa acgcatagca gaaatggaaa aaaaagaaaa
     1141 aactgacaaa atagacaaaa cggggtccaa acgtggagct gctttatatc agtttaatga
     1201 gaaggcatac cgcaaagctc cgaaatttaa gctctgagaa cctaatattc aacaacttgt
     1261 aattagtaat ttaaataata tgctggaagc actgaaagac aaagtattcc atgctaacct
     1321 tgaactggtg aagcacggat tggttatctt cacatggggc aatgtatcgg gcattgaccg
     1381 cgaatctggt ctggtagtca tcaagcccag tggggtgagt tacgatgaaa tgaaagcaga
     1441 ggatatggtg gtagtgaatc ttgacggcaa ggtcgtggaa ggacggttaa agccctcttc
     1501 agacacgccg acccacctgg ttctctataa agcattcccc gaaatcggcg gtgtggtgca
     1561 cacgcactct acttacgcca cagcctgggc acaagccgga tgtgacatac cgaatatcgg
     1621 gacaacacat gccgattact tccacgacgc cataccctgc acagcagaca tgacgaagga
     1681 ggaagtggaa ggagcgtatg aactggaaac gggaaatgtc atcgtaaaac gctttgaggg
     1741 gctgaacccg gtacatactc ccggagtatt ggtaaagaac cacggtcctt tctcgtgggg
     1801 aaaagacgca cacgaagcgg tacataatgc cgtagtgatg gagcaggtgg caaaaatggc
     1861 aagtatagcc tatgccgtga accccaatct gaccatgaat ccgttactga tagaaaagca
     1921 tttcagccgc aagcacggtc ctaacgctta ttatggacag aaataactat cattctttaa
     1981 atataaacta taaaaataaa ttgtatgaac gcatttgaac aatatgaagt atggttcgta
     2041 accggagcac agctcttgta cggaggtgac gcagttatcg cggtagacgc acatagcaat
     2101 gaaatggtga aaggtctgaa tgattccgag aaactgcccg taaaggtagt atataaaggt
     2161 acggtcaatt catccaaaga agtaactgct gccttcaagg ccgccaacaa cgacgaaaag
     2221 tgtatcgggg tcatcacctg gatgcacacc ttctctcctg ccaaaatgtg gattcacggt
     2281 ttgcaggaac tgaagaagcc attactacac ttccatacac agttcaacaa ggaaattccc
     2341 tgggagacga tggacatgga ttttatgaac ctgaaccaat cggctcacgg cgaccgcgag
     2401 ttcggacaca ttgtgacacg tatgcgaaag aaccgcaaag tggtagtagg ccactggcag
     2461 gacgaaaaag cccaaaacca gattgccgca tggatgcgcg tagctgccgc atgggctgat
     2521 gcgcaggata tgctcatcat ccgcttcggc gaccagatga acaacgtggc tgtgacagac
     2581 ggtgacaagg tcagcgccga acaggtattg ggctatcatg tggactacta tcccatcaat
     2641 gatgtgatga catactacaa tgctgtcagc gacgaggacg tgaaggcact cgtagcagaa
     2701 tacttcaagc tctacgacca cgctcccgaa ctggaagacg cacgtacgga agcctacacc
     2761 aaagtatgga actccgccaa ggccgaaatc gccattcgcc gcgtgctgaa agacacgggt
     2821 gccaaaggct tcaccaccaa cttcaacgat ttgggcgact ttgaccaaat ccccggactg
     2881 gcctcacagc gactgatggc agaaggttac ggcttcggtg ccgaaggcga ctggaaaact
     2941 gcagcactgt accgtaccac ttgggtgatg agtcaaggta tgccgaaggg gtgctccttc
     3001 cttgaagact atacgctgaa cttcgacgga gaaaagagcg ccatcctgca agcacatatg
     3061 ttggaagtct gcccactgat tgccgaacag aagccgaaac tggaagtgca ccgtctgagc
     3121 atcggtatcg acagcgaaac agcccgcctg gtatttacca gcaagcaagg tgaaggtgta
     3181 gccgctacca tcgtagacct gggcaaccgc ttccgcctca ttgtgaacaa agtagaatgc
     3241 atcaagagca agcctctgcc caagttgccc gttgccagtg cactgtggat tccaatgccc
     3301 aacctcgagg tgggcgctgc agcctggatt ctggccggag gtacacatca taccagcttc
     3361 tcctacgact tgacggtgga atattgggaa gactttgccg aaatggccgg catcgaaatg
     3421 gtggttatcg atgaaaatac caccattagc gagttcaaaa aagaattgcg tatgaatgaa
     3481 gtctactata tgctgaacaa ggcactttgc tgataatcat tacagattac cgattgcgga
     3541 ctactaatta cacgtaccac aaacgtaact agtagtttgc aatcagtaat ccgtagttta
     3601 taatcgtact ataaatccgt aatttatcat taataccatg aaattagatg caaaatcaac
     3661 cattgaggca ggtaaggcca tccttggtat agaactcggt tccacacgaa tcaaggcggt
     3721 tttgattgac caggaaaaca aacccatcgc ccagggaagc catacttggg agaatcagtt
     3781 agtcgacgga ctgtggacat atagcgtcga ggctgtctgg tatgggttgc aggattgcta
     3841 cgcagacctt cgtaccaatg taaagagcct ctacgataca gagatagaaa ccctggcagc
     3901 catcggtgtc agtgccatga tgcacggcta tatggcattc aatgaaaaag aagaaatcct
     3961 tgtacccttc cgtacctgga gaaatactaa taccagccag gctgccgcag ccctatccga
     4021 actatttgtc tacaacatcc ctctgcgttg gagcatctcc cacctctacc aagccatcct
     4081 ggataatgaa gagcacgttc catccatcaa ttacctgacc acccttgcag gttttgtcca
     4141 ctggcaaata accggccaaa aggtactggg cataggagat gcctccggta tgctccccat
     4201 cgatcccatc accaaaaact attcttctga aatggtggat aagttcgaca aacttattgc
     4261 tccgaaagga tacgactgga aacttcggga tattctgccg aaggtattgt cggccggtga
     4321 aaacgcaggc ttccttactc ccgaaggagc cagtcgcctc gacgtatcgg gacatctgaa
     4381 agcaggaatt cccgtctgtc cacccgaagg tgacgctgga accggcatgg ttgccaccaa
     4441 cgccgtaaag cagcgcactg gaaacgtatc ggcaggcacc tcctctttct caatgattgt
     4501 attggaaaaa gaattgtcca agccctacga aatgattgac atggtaacca cccccgacgg
     4561 aagcctcgta gctatggtgc attgcaacaa ctgcacttcc gacctcaatg cctggatcaa
     4621 tattttcaaa gaataccagg aactgatggg tatccccgta gatatggacg aaatctacgg
     4681 aaaactctat aaccacgccc tgacaggcaa tgcagattgc ggaggcctca tctcttacaa
     4741 ctacatatca ggcgagccta taacgggact ggcagccgga cgtccactgt ttgtacgttc
     4801 ggcaaacgac aagttcaacc ttgccaactt catgcgcacc catctgtatg cttcagtggg
     4861 agttctcaaa atcggcaacg acatcctttt caatgaagag aaaatcagag tagacagaat
     4921 caccggtcac ggaggactct tcaaaaccaa aggagtaggc cagagaatac tggcagctgc
     4981 catcaattca cccatttccg ttatggaaac agccggcgaa ggtggtgcct ggggtattgc
     5041 cctcctcgct tcctaccttg caaacaacgg aaacgaccaa tcccttgccg acttcctgga
     5101 caagcatgta ttcaccggaa atgccggtat tgaaatctca ccgacagccg aagatgtaag
     5161 cggattcaac acctacattg aaagctataa agcaggtttg cccatcgaag aagcagcagt
     5221 aagattcaag aactaagtat ttaataacac taaaaaacta tgaacacaaa gttatttatc
     5281 agtagcatat ttctctccac ctcgttgtca ctcttcgcac agaaaagtgc cactatcact
     5341 ttacacacag accagagcgg gcaaatcatt cccaaagaaa tctacggcca atttgcagag
     5401 catttgggaa cttgtatcta tggcggactt tgggtaggtg aaaactccga tattcccaac
     5461 atcaacggtt atcgcaccga cgtattcaat gcactgaagg agctccgtgt acccgtcctc
     5521 cgctggccgg gcggctgttt tgccgatgaa taccactgga tggacggtat cggccctaaa
     5581 gaaaaccgcc ccaaaatggt gaacaacaac tggggaggca ctatcgaaga caacagtttc
     5641 ggaacccatg agttcctcaa tctctgcgaa atgctgggtt gtgaacccta tatcagcgga
     5701 aacgtaggca gtggtaccgt agaagaactt gccaaatggg tggaatacat gacctccgaa
     5761 ggagactccc ccatggcacg cctgcgccgc cagaacggtc gcgacaaagc ctggaaagtg
     5821 aaatacctcg gtgtgggtaa cgaaagctgg ggttgcggtg ggagcatgcg tcccgaatat
     5881 tatgccgacc tctaccgccg ctattccacc tactgccgca actatgacgg caatagcctc
     5941 ttcaagatag ccagcggtgc cagcgactac gactataact ggaccaaagt gctgatggac
     6001 cgcgtaggcg gccgtatgca cggtctttcc ttgcactact ataccgtcag cggatggaac
     6061 ggcagtaaag gcgccgccac ccgattcagt aaagacgatt attactggac actgggcaaa
     6121 tgccgcgaaa tagaagatgt catcaagaag cattgcacca ttatggataa atacgaccct
     6181 caaaagaacg tagctcttat gcttgacgaa tggggaacct ggtgggacac tgaaccgggt
     6241 accaatcccg gacatctgta ccagcagaat acattgcgtg atgcttttgt cgcctccctc
     6301 agcttcgaca tcttccataa atataccgac cgtctgaaaa tggcaaacat tgcccaaatc
     6361 gtcaatgtat tgcaatccat gattctgacc agcggaaaaa acatggtact cacccccact
     6421 tattatgtat tcaaaatgta caatgtacac caggatgcca cctacattcc tcttgagctg
     6481 aactgcgaca tgatggatgt acgcgacaac cgcagaatac caatggtcag cgctaccgcc
     6541 tccaaagacc caaacggcaa gatacacatt tccatgtcca acgtagatgc agacaatgca
     6601 caggaagtga ccatcaatct gtctggaacg aaagccaaga aagcagttgg tgaaatattg
     6661 acttccacca atctgacgga ctacaattca tttgaaaatc ccgacaatgt gaaacccgtt
     6721 ccgttcaaag aggtaaaaat caataaagat attctcaaga ttaaacttcc ggccaaatca
     6781 atcgttacta ttgagttaca gtaaaactac cgtgcaccgc acaaaatcag ctaaatacgt
     6841 ttagtatcat tttagcagca aaaaggcagt aatactgata aaaaagacac tcttcgagtg
     6901 ttgtgaatta cgcataaaga gttatctttg cccttggaaa acctacaagg accaaataac
     6961 ctattgataa tattcaaaat taattagatt caatatgaac gacaacaaac ttatgaaccg
     7021 tgcggcggac aatatccgta tccttgctgc atccatggtt gagaaagcca actccgggca
     7081 tccgggcggt gccatgggtg gtgctgactt tgtaaatgta ctcttctcag agttcctggt
     7141 atatgaccct gaaaatccgg cttgggaagg tcgtgaccgt ttcttcctcg acccgggaca
     7201 catgtcaccg atgctttact ctacattggc cctgaccggc aagttcacgc tggacgaact
     7261 gaaagagttc cgccaatggg gaagccctac tccgggacat cccgaacgtg acatcatgcg
     7321 cggcatcgaa aacacttccg gaccgctcgg ccagggacac acatttgcag tcggtgcagc
     7381 catcgcagcc aagttcatga aggcacgttt cgaagaagta atgccacaga ccatctacgc
     7441 ttatatttct gacggtggca tccaggaaga aatctcccaa ggctcaggcc gtatcgccgg
     7501 agcattaggg ttggataatc tcatcatgtt ctatgatgcc aacgacattc agctttctac
     7561 cgagacaaag gatgtgacca tcgaagatac cggcaagaaa tacgaagctt ggggctggaa
     7621 agtcattaaa atcaatggta acgatcccga tgccatccgc ggtgcactga acgaagccaa
     7681 agctgagaaa gagtgtccga cgctgattat cggccatacc gtaatgggta aaggtgcccg
     7741 caaggcagac ggcagcagct acgaagctga ttgtgccacg cacggtgctc ctctgggcgg
     7801 cgacgcttat ataaacacta tcaagaattt gggtggtgac ccgacaaatc cgtttgtcat
     7861 cttccccgaa gtggccgaac tatatgccaa gcgtgcaact gagctgaaga aaatcatggc
     7921 tgaaaagtat gcagccaaag ccgtatgggc aaaagccaat ccggaaaagg ctgccaaact
     7981 ggaaatgttc ttctccggca aggctcccga agtgaattgg gccgccatcg aacagaaagc
     8041 aggcgttgcc acccgcgcag catctgccac tgtgctcagt gctctcgcca ctcaagtaga
     8101 aaatatgatt gttgcttctg ccgacctttc caattccgac aagacagacg gattcctcaa
     8161 gaaaacacat gccttcaaga aaggtgactt cagcggtgca ttcttccagg ccggtgttgc
     8221 cgagctgact atggcatgtt gctgtatcgg tatggcactg catggcggtg taatccccgc
     8281 ttgcggaact ttcttcgtat tctccgacta catgaaacct gccgtacgta tggcagccct
     8341 gatggaagtt cccgtgaagt tcatctggac acacgatgcc ttccgtgtag gtgaagacgg
     8401 tcctacccat gaaccggtag agcaggaagc ccaaatccgc ctgatggaaa aactgaaaaa
     8461 ccacaaggga cataattcca tgttggtact ccgcccggca gatgcagaag aaacaactgt
     8521 ggcatggaaa ctggcaatgg aaaataccac aaccccaacc ggtttgattt tctcccgcca
     8581 gaacatcgcc aacctgcccg aaggcaacga ttacgaacaa gctgccaaag gcgcttatat
     8641 tgtagccggc tccgatgaaa atccaaatat aatcctcgtt gcttcaggct cggaagttgc
     8701 cacattggta gccggtactg aattgctgcg caaggatggc atcaaggtgc gtatcgtgtc
     8761 cgttccttcc gaaggtctgt tccgtagcca agctccggga tatcaagaag gcattatccc
     8821 gtgtggtgcc aaggtattcg gcctgacagc cggtctgccc gtcacactgc aagggctggt
     8881 aggtccccgc ggtaaagtat ggggattgga atcattcgga ttctcggcac cttataaagt
     8941 gctggacgaa aagctcggtt tcaccgcaga gaacgtttac aaacaagtaa aagcaatgtt
     9001 ataatcatta tccaatgtgc tgatgtgctg attgcccgcg ccctacaagc tgcaggcatc
     9061 agcacattgg cacattggta tattaactga ccatcatgaa aacaatagga atctgttccg
     9121 accatgcagg cttcgaattg aaggaatatg ttcgcggctg gttggaagcc aaaggctggg
     9181 cttacaagga cttcgggacc tactcaaccg agagttgcga ctatcccgac tttgcacatc
     9241 ctttggcact ggccgttgaa gccggagagt gctatccggg aattgccatc tgcggaagcg
     9301 gtgaaggtat cagcataacg ctgaacaagc atcagggtat ccgcgcagcc ctctgctgga
     9361 cggcagaaat agcccatttg gcacgccagc acaatgatgc caatgtgctt gtcatgccag
     9421 ggcgattcat cagtaccgaa gaagccgaca tgattatgag ggaattcttc agtacaccat
     9481 tcgaaggcgg acgccaccaa cgaagagtgg acaagatacc ggtacacttg taaagcaata
     9541 gaatcacctt ctttatgata tccgcccgaa gctctgacat tctgatagaa tcgtgagaaa
     9601 cttcgggctt tttatttgcc cctttttctt atttttcaca gtgaagatgc tcattgtctt
     9661 caaataaaaa ctatctttgt ggttcgataa cccggatatt ttttagatat ggaacgactg
     9721 aataccataa aagagcttat caaccaggga aatgtagagc aagccatcca gcagcttgac
     9781 gaaatactgc aaacagactt tcccggcaaa gacgaagctt actacctgcg gggaaatgcc
     9841 tatcggaaac aaggcaactg gcaacaagca ctgaacaact atcagtatgc catcgacctg
     9901 aaccccgaaa gcccggcaca acatgcctat caaatggcta tggacatcct gaacttctac
     9961 aacaaggata tgtacaatca ataaataaag aacgtaaatt atggcaaaaa tcaaaggagc
    10021 aatcgtagta gacaccgaac gttgcaaagg ctgcaacttg tgtgtggtag cgtgtccgct
    10081 caacgtaata gccctcacca aggaggtgaa tgtgaaaggg tataactatg cccaccaaat
    10141 attggaagat acttgtaacg gctgcgcctc gtgcgccaca gtatgtccgg acggatgtat
    10201 ctcagtatat aaaataaaag tagaataaat ctgtaaatca gtagaatatg gcagaagaag
    10261 ttgtattaat gaaaggaaac gaagccatcg cccacgcagc catccgttgc ggtgcagacg
    10321 gttacttcgg atatcccatt actccgcaat cggaggtatt ggaaactctt gccgaactga
    10381 aaccctggga gacgaccggc atggtggttc ttcaggcaga aagtgaagtg gcagctatca
    10441 atatggtgta cggcggtgcc ggaagtggta aaatggtcat gacctcctcc tccagccccg
    10501 gtgtcagcct aaagcaggaa ggtatctctt atctggcagg tgccgagctg ccttgcttga
    10561 ttgtaaacgt tatgcgcggc ggtcccggtc tgggaaccat ccaaccgagc caggccgact
    10621 atttccagac agtaaaagga ggcggccacg gtgactatcg tctgattgcc cttgctccgg
    10681 cttccgtaca agaaatggca gatttcgtag gactggcatt cgaacttgcc ttcaaatacc
    10741 gtaatccggc aattatcctt gccgacggtg tcatcggcca gatgatggaa aaagtggtgc
    10801 tcccggtaca aaagccacgc cgcaccgatg cggaagtcat cgaacaatgc ccatgggcca
    10861 ctaccggcag aaccaatggc cgcaaaccca acgtcatcac ctcattggaa ctgaaaccgg
    10921 aagaaatgga aaagaacaac atccgtttcc aggccaaata caagcagata gaagagaatg
    10981 aggttcgctt cgaggaaatt cattgcgatg atgccgacta cctgattgta gccttcggct
    11041 ctatggcacg catcggacag aaagcaatgg agctggcacg cgaagaagga ataaaggtag
    11101 gtatgctccg ccccatcacg ttgtggccgt tcccgaccaa agccattgcc gcgtatgccg
    11161 acaaggtgaa aggtatgctc gttacagaat tgaatgccgg acagatggtg gaagatgtcc
    11221 gccttgccgt gaacggtaaa gtgaaagtag aacatttcgg acgcctcggc ggcattgttc
    11281 ccgatccgga tgagatagta gatgcattga aagaaaaact gattaagaaa tgaatcctga
    11341 taaaataaga aacgtactga acattctctt catggtactt gccctggcag ctatcattat
    11401 atattttgct gcaaaagatg acttcaagct gttcatctac gtctgcggcg cggcgatatt
    11461 cgtcaagttg atggagtttt tcatacggtt caccaacaga taggagaagt gattatgaca
    11521 aaagaagata ttataaagcc cgagaatctg gttgccaaga aaccgactct gatgaacgac
    11581 aatcccatgc actactgccc gggatgcagt cacggcgtag ttcataaact cgtagccgaa
    11641 gttatcgaag aaatgggact ggaagacaaa gcaataggca tctcccccgt gggatgtgcc
    11701 gtgttcatct ataattatat agacatcgac tggcaggaag ccgcccatgg acgtgcgccc
    11761 gcacttgcca ctgccatcaa gcgcctttgg ccagaccgcc tggtgttcac ttaccaagga
    11821 gacggcgacc tggcttgtat cggtactgcc gaaaccatcc acgccttgaa ccgcggcgaa
    11881 aacatcacca tcatcttcat caacaatgcc atctatggta tgaccggggg acaaatggct
    11941 cccactaccc ttgtaggcat gaagacatcg accagccctt acggacgtga cgtgcatctg
    12001 cacggctatc cgctgaagat ggccgatatt gctgcacaat tggaaggaac cgcttacgtg
    12061 acacgccaaa gcgtacagtc cgttcccgcc atccgcaaag cgaaaaaggc tatccgcaaa
    12121 gcattcgaga actctatggc aggcaaaggt tccaaccttg tggaaatcgt ttccacctgt
    12181 aactccggct ggaagatgtc tcctgcgaaa tccaatgaat ggatggtaga gaacatgttc
    12241 cccttctatc cgctgggcga cctgaaagat aaataatcat gctaaagaca gaagaacaat
    12301 gaaagaagaa atcattatag caggcttcgg tggacaaggt gtattgtcca tgggaaagat
    12361 tttggcatat tccggattga tggaaggcaa agaggtgact tggatgccgg cttacggacc
    12421 ggaacaacgt ggtggtacag ccaacgtaac agtcatcgta agtgacgaga aaatatcctc
    12481 acccatctta agcaagtacg atgccgccat catcctgaac cagccgtcac tggagaaatt
    12541 cgaaagcaag gtaaaacccg gaggcgtact tatctacgac ggttacggca tcatcaaccc
    12601 gccgacgcgt aaggacatcc acgtttaccg catcaacgcc atggatgccg ccaatgaaat
    12661 gaacaacgcc aaggcattca acatgattgt attgggtgga ttattgaaaa tcaagccgat
    12721 ggttacactg gacagtgtac tcagaggatt gaagaagaca ctgcccgaac gccaccacca
    12781 cttgataccg atgaacgaag aagctatcaa gaaaggaatg gaacttattc aggaaatgaa
    12841 atgaaaggct atgtaaagcc actccccata agaggaggaa ctttacgcca gaataagaga
    12901 taaaggaaaa cggataagcc cttgtgatat tgatttattg caagggctta tttcatttca
//
