LOCUS       c00061_gnlPro..        12771 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKBIDGBN_61.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:13:43
            Original ID  :: gnl|Prokka|BKBIDGBN_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12771
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12771
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7245:10803](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(7246..10803)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..12771
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12771
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             21..1766
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="VAVFTCQAINPPFVIKHLGDGQSIVQIDEQKKFLLLPVEEASPEA
                     KLYMIADNDVVRSMNVRLAVNKVDYFVPVDLTGFDNKHLSFNFQLIPDSALCWEEMKLS
                     DEFDVSNREKYRPVYHFSPAYGWMNDPNGMFYKDGVYHLFYQHNPYGSMWGNMHWGHAT
                     STDLVTWEHHGDAISPDALGTIFSGSCVVDKDNTAGFGAGAVIAFYTSASDRQVQSMAY
                     SLDNGKTFKKYARNPILTSTQRDFRDPKVIWHEDTKKWIMVLAVGQEMEIYSSADLKSW
                     TLESKFGEGQGAHGGVWECPDLLELPVEGTELKKWVLVCNLNPGGPFGGSATQYFVGTF
                     DGKRFVNESPAVTKWMDWGKDHYATVTWSNAPAGRAIALAWMSNWQYANDVPTRQYRSA
                     NSVPRDLSLYTSEGETYVKVTPSPELLKLRDKGSKKRAFKVDRTYNLDKLLNDNSGTYE
                     IEMTIKNKDADVIGFQLFNSKGEEVEMYYNLAEKTFTMDRIKSGEVSFSKDFPAVTVAP
                     VEGGNEMKLRLFVDKSSIEAFGNDGRFAMTNLVFPSEPYNRISFYAKGGSCNVTSFIVY
                     KLGLK"
     CDS             1785..2951
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 100.2; E-value: 3.8e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="MFS_1 (E-value: 5e-32, bitscore: 100.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNSSLAKLFPVMLCFFAMGFVDLVGIASNYVKADLNLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDGYVLMLLSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASSLTFGQFVKAIASFLAPYIAMWGATQAIPS
                     LGMGWRVLFPVYMVIAVIAILWLSGTSIREEKEEGRPSTFGECLALLGKPFIFLCFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAPRTF
                     FGISVLCMLAAMVGLFVFHEKAMIYICIALIGFGNSNIFPVIFSQALLAMPQKKNEVSG
                     LMIMGLFGGTVFPIAMGLASDAVGQSGAVAVMTVGVVYLFFYMLRMKR"
     CDS             3186..4073
                     /locus_tag="ctg61_3"
                     /transl_table=11
                     /translation="MNKIIVGMGEALWDCLPEGKKIGGAPANFAYHASQFGFDSRVVSA
                     VGADADGDEILDVFARKGLRTQIERVPYPTGTVQVTLDAVGVPCYEIKEGVAWDNIPFT
                     DELKRLALNTRAVCFGSLAQRSETSRITINRFLDTMPDAEGQLKIFDINLRQGFYTKEI
                     LCESMRRCNILKINDEELVTISRIFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGVVSFQETPKVPVADTVGAGDSFTAAFTAAILSGKQVPDAHKLAVEVSAYVCTQSG
                     AMPELPVALKERLA"
     CDS             4145..6904
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.4e-17, bitscore:
                     51.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQHNLRILFFLLVLWGVAVACSRREARFRIGVSQCSEDEWRRQM
                     NSEILREAHFYEDVEVDIRTAVDDNDRQAKDIRELIAEGVDLLIVAPNEATPITPVVEE
                     AYNRGIPVIVVDRKILSDKYTAYVGADNYEIGKAVGEYVANVLHGQGDVVEISGLVGST
                     PAVDRHQGFVKAISAYPGIRLLAVEDGAWLQLKAGEKMDTLLSRFPHIDLVYAQNDRMA
                     AGAYAAAAREGREKDMRFIGIDALPGKDYGVEKVLAGELDATFIYPTGGDRVMQIAMDI
                     LNKRDFPRETILGTSVVDRDNALIMKMQTAHIGTLDGKIETLNGKINQYLASYATQQVV
                     LYGSLSALLLLVGLLVAVYLSLRAKNRLNRELSMQKKKLEEQKTQLIQQKELLEVQKSQ
                     LEQLSHELEEATHAKLVFFTNISHDFRTPLTLIADPIEQLLANRTLDGQPRQLLELMKK
                     NVHILLRLVNQILDFRKVENGRMELHLEPFDLLDSFRGWNDSFRMALLKKHIAFSFEAS
                     PDTDFRMMADAEKMERIYFNLFSNAVKYTPENGKITVRLLKSEQNYSLSVFNSGSYISS
                     TDVEAIFERFYQVDGHQAGTGIGLALVRAFVEMHGGNITARSDEKGTTFIVTFPQQDVS
                     QYHPTIVTLPAEEKDVSSTLIDTEVKACEEVVEADCPTVLVIDDNADIRNYVKSLLSNE
                     FRVLDAADGTEGIRLAMKYVPDVIISDVMMPGMDGVECCRRLKGELQTCHIPVILLTAC
                     SLDEQRIQGYDGGADSYISKPFNSQLLLSRVRNLIANRRQLRQFFGDNQTIEKEAISDL
                     DKGFVSRFKSLVEERMKDAELNVEDLGRNMGMSRVQLYRKLKSLTNYSPNELLRQMRLK
                     KAASLLASSDMTVAEIAYEVGFSSPSYFTKCYKEQFGESPTEFLKRRG"
     CDS             complement(6967..7155)
                     /locus_tag="ctg61_5"
                     /transl_table=11
                     /translation="MIGFIIWIIGVVLCVKAVLEIMKWPVDGVKKLLVAIIILLTSWIG
                     ICVYYFWGRENLPQILK"
     CDS             complement(7246..10803)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_6"
                     /sec_met_domain="PFOR_II (E-value: 1.5e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6.5e-83, bitscore: 267.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 4.9e-32, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.7e-13, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.8e-13, bitscore: 38.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.3e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2e-26, bitscore: 80.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGLVAVHLYRPFSAKHFLAAVPKTAKKIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILAVYKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWANLADDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFTQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLPEAANWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKAMEDAIAAEGTPAEYKEVFQAWIENMYDADKSKE
                     LAEKIIPMVEAAKDKCDSCKTIASLSQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQAEEEKAVKCGYWHLWR
                     YNPALEAEGKNPFTLDSKEPDWSGFQDFLKGEVRYASVMKQYPQEADELFKAAEENAKW
                     RYNSYKRLSKENWGAEVTE"
     CDS             complement(10845..12023)
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MEAFYRTHAYLVEHTNAPVRRDLMDEIDWNDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHGIVEFAAEFQRRGGKVLLIDQVFKYPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENMELRDIVKSYNLRGFSFREYLNLQTGMKFH
                     AYPLEEILSNHEQIAKGILSKVRPLDYIQDYMHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLANDIQTSRATVMNYIKYLADAR
                     LINMVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANTMWKDHKVNKGD
                     KNISFMVDEVMPFKICPEGTKIKNNPGVTYVLHKAEIGRGNQIPLWLFGFLY"
     CDS             12152..12769
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="MKLYVFNPDADMALGNNEENYMAPATIRRMAEDLALLPIWYAQPG
                     SGVLASSAYNADYLKQMQQLFRLDVHLVTEPELPDYADVRVMPWGWNPAIRKRMLKGGV
                     LEKNLPTPDALDKYRMKAARSNALAFRALFYFNKIDYTCGDGCCLVEADGRMTDISPDI
                     VDRYKEGCVFKSLWSGSEKGLCWCRKKKKKNVSDWCSRALKEN"
ORIGIN
        1 tatttatatt aggaactacc gtggctgtct tcacatgcca ggccataaat cctcctttcg
       61 tgattaaaca tctgggtgac ggacagagta tcgtccaaat tgacgagcag aagaagtttt
      121 tgctgctgcc ggtggaagag gcttctccgg aggcaaaatt gtatatgata gcggacaatg
      181 atgttgtacg cagtatgaac gtgcgattgg cagtcaataa ggttgactat tttgttccgg
      241 tcgatttgac cggcttcgat aataaacatc tctctttcaa cttccagctt attccggatt
      301 cggccttatg ctgggaagaa atgaaactgt cggatgaatt cgatgtttcg aaccgggaga
      361 agtaccgtcc ggtgtatcat ttcagcccgg cttacggttg gatgaatgat cctaacggaa
      421 tgttctacaa agacggggtc taccatttgt tctaccagca taatccctac ggctccatgt
      481 gggggaacat gcattgggga catgccacca gtacggacct cgtcacttgg gaacatcacg
      541 gagatgctat ttcgcccgat gcgctgggaa caattttcag tggctcttgt gttgtcgaca
      601 aggataatac ggccgggttc ggtgccggtg ccgtcattgc cttctataca tcggcaagcg
      661 accgtcaagt gcagagcatg gcctatagcc ttgacaacgg aaaaaccttc aagaagtatg
      721 cgcgaaatcc catcctgact tccacgcagc gcgacttccg tgaccctaaa gtcatctggc
      781 acgaagatac caagaaatgg atcatggttc ttgccgtagg gcaggaaatg gaaatatact
      841 cttctgccga cctgaagagc tggacgctgg agagcaaatt cggtgaagga caaggtgctc
      901 acggcggagt ctgggagtgt cccgacctgc ttgaactgcc ggttgaaggt acggaactga
      961 agaagtgggt actcgtctgt aacctcaatc cgggtggacc gttcggtggc tctgccacac
     1021 aatatttcgt ggggacattt gacggaaaga gattcgtgaa cgagtctccc gcagtgacga
     1081 aatggatgga ctggggaaaa gaccattatg caactgtcac ttggagcaat gctcctgcag
     1141 gacgtgccat tgcattggca tggatgagca actggcaata tgccaacgat gtgcccaccc
     1201 gccaataccg tagtgccaac tccgtgccgc gcgacctttc gctctatacc tcggagggtg
     1261 aaacctatgt aaaggtaacc ccgtctcccg aattgctgaa actgagggat aaaggcagca
     1321 agaagcgtgc tttcaaggta gaccgcacgt ataatctgga caaactgctg aatgacaatt
     1381 ccggaacgta tgaaatcgaa atgaccatca agaacaagga tgcggatgtg ataggattcc
     1441 agctctttaa ctcgaaaggc gaggaggtgg agatgtacta taacctggcg gaaaagacgt
     1501 tcaccatgga ccgtatcaag agtggtgagg tgtcgttcag caaggacttc cctgcagtga
     1561 ccgtggctcc tgtcgagggt ggcaatgaaa tgaaactccg cttgttcgta gacaagtcga
     1621 gcattgaagc gtttggcaac gacggacgtt ttgccatgac aaatcttgta ttcccgtcgg
     1681 aaccttacaa ccgcatcagt ttctatgcta aaggtggaag ctgcaatgtc acctcgttta
     1741 ttgtgtacaa actcggatta aaataacaga taataatctt cagcatggaa aatactaaga
     1801 attcttcctt ggcaaagctc tttccggtca tgctttgctt cttcgccatg ggctttgtgg
     1861 atttggtggg catcgcctcc aactacgtga aggccgactt gaacctgacc gactcgcaag
     1921 ccaacatatt cccgtctctg gtgttcttct ggttcctcat cttctccgta cctacgggta
     1981 tgctgatgaa ccgcatcgga cgcaagaaga cggtgcttct cagccttgtc atcacgtttg
     2041 cctctttgct tctcccggtt ttcggagacg gctatgtgct gatgctgctc tcgttctcat
     2101 tgctgggcat cggcaatgcg ctgatgcaaa cgtcgctcaa cccgctgctt tccaatatcg
     2161 taagcggcga gcggctggca agttcgctca ccttcggaca gtttgtaaaa gccattgctt
     2221 cgtttctggc tccatacatc gccatgtggg gagctacgca ggccattccg tctctgggca
     2281 tgggctggag ggtgctgttc ccggtctata tggtcattgc ggtgattgcc attctctggc
     2341 tgagcggtac ttccatccgc gaggaaaagg aagagggacg cccttccacc ttcggggagt
     2401 gcctcgctct gctgggcaag ccgtttatct ttctctgctt cctgggcatc atgtgccatg
     2461 tgggcattga tgtaggtacg aataccacag cgcccaaaat cctgatggag cgtctgggca
     2521 tgacgctggc cgatgccggc tttgccacca gcctttactt catcttccgc acggcgggtt
     2581 gctttctcgg agccttcatc cttcagaaga tggctccccg aaccttcttc ggcatcagcg
     2641 tgttatgtat gttggctgcg atggtagggt tgttcgtttt ccatgaaaag gcaatgatat
     2701 acatctgcat tgcccttatc ggtttcggca attcgaacat ctttccggtt atcttctccc
     2761 aagcgttgct tgctatgcca caaaagaaga acgaggtttc cggcttgatg attatggggc
     2821 tcttcggcgg tacggtattt ccgatagcaa tgggcttggc aagtgatgct gtaggacaaa
     2881 gcggtgccgt ggctgtgatg acggtagggg tagtgtactt gttcttctat atgctgcgta
     2941 tgaagcggta atctttgttc gcaggctgcg gacacatatc ccaaggctgc ggatatctgt
     3001 cccaaggttg cggatgtcta tcccaagcct tgggatagag ataatcctta gttcttagag
     3061 actttttaat agataattgg caacttttca ttctatagtt aggaactttt ttattaggtt
     3121 tgcagtgggt aggacattga gtttgccgtg aataaaatat atcattcatt aaacaatata
     3181 atattatgaa taagataata gtaggtatgg gcgaggctct gtgggactgc ctccccgaag
     3241 gaaagaagat aggcggtgct ccggcaaact ttgcttacca tgcatcgcag tttggtttcg
     3301 acagccgtgt ggtcagtgcc gtaggtgccg atgcggatgg ggacgagatt ctggatgtgt
     3361 tcgcccggaa ggggctgcgc acgcagattg agcgcgtgcc ttaccccacg ggaacggtgc
     3421 aggtgacgct cgatgccgtg ggcgtgccgt gctatgagat aaaagaaggc gtggcctggg
     3481 acaacattcc ctttaccgac gaactgaagc gtctggcact gaacacgcgt gccgtatgtt
     3541 tcggctcttt ggcgcaacgc agtgaaacaa gccgcatcac catcaaccgt tttctcgaca
     3601 cgatgcccga tgcggagggg caactgaaga tattcgacat caatctccgc caagggttct
     3661 ataccaaaga gatactctgc gaatccatgc gccgctgcaa catcctcaag ataaacgatg
     3721 aggagctggt gaccatcagc cgtattttcg gctacccggg catcgacttg caggacaaat
     3781 gctggattct gctggctaaa tataacctga aaatgcttat cttgacttgt ggaacgaacg
     3841 gcagctatgt gttcactccg ggagtggttt ccttccagga gacgcccaag gtaccggtgg
     3901 cggacaccgt tggagccggt gactcgttca cggcagcctt caccgctgcc attctcagcg
     3961 ggaagcaggt gcccgatgcc cataaactgg cggtggaagt ctctgcctat gtatgtaccc
     4021 agagcggtgc catgccggaa ttgccggtgg ccttgaaaga aaggctggca tagatttttc
     4081 ttattctttt cacatttttc gttatctttg ctcatctgca atcttaaatc agaggaaagt
     4141 gaagatgaga cagcataacc ttcggatttt attctttttg ctcgtgcttt ggggagtggc
     4201 ggttgcctgc tcccggcgcg aggcacgttt ccgtatcggc gtttcccaat gtagcgagga
     4261 tgaatggcgg cgccagatga acagtgagat actccgtgaa gcccatttct acgaggatgt
     4321 ggaggtggac atccgtactg ctgtcgacga taatgaccgt caggcaaaag acattcgtga
     4381 gctgatagcc gaaggggtgg atctgctgat tgtggcccct aatgaagcca ctccgataac
     4441 tccggttgtg gaggaggcat acaaccgggg cattccggtg attgtagtgg accgtaaaat
     4501 cctttcggac aaatacacgg cctacgtcgg tgcagacaac tacgagatag ggaaagctgt
     4561 gggagagtat gtggccaatg tgctgcatgg gcagggagat gtggtggaaa tctcaggttt
     4621 ggtgggctcc acacctgccg tagaccgtca tcaaggattt gtgaaggcta tatccgctta
     4681 tcccggtatc cggttgctgg ccgttgaaga cggtgcctgg ttgcaactca aggccggaga
     4741 gaaaatggat accctgctga gccgctttcc gcatatcgac ctggtgtatg ctcagaatga
     4801 ccgtatggcg gccggagcct atgctgccgc tgcccgagag gggcgggaaa aggatatgcg
     4861 gttcatcggc atagatgccc tgcccggcaa ggactatgga gtggagaaag tgcttgccgg
     4921 cgaactggat gccacgttta tatatcctac cggtggcgac cgcgtgatgc agattgccat
     4981 ggatattctg aacaagcgtg atttcccccg tgaaactatc ctgggcactt ccgtcgtcga
     5041 ccgcgacaat gctctcatca tgaagatgca gaccgcccac atcggcaccc tggatggaaa
     5101 gatagaaacc ctgaacggaa agataaacca gtatttggcc agttatgcca cgcagcaggt
     5161 tgtcttgtac ggcagtctgt ctgccctatt gttgctggtc ggtttgttgg tggctgtcta
     5221 cctctccttg cgtgccaaga accggttgaa ccgtgagctg tccatgcaga aaaagaaact
     5281 ggaagaacag aaaactcagt tgatacagca gaaggaactg ttggaagtgc agaagtcgca
     5341 gttggaacag ctttcccatg aactggagga ggctacgcac gccaagctgg tgttcttcac
     5401 gaatatttca cacgatttcc gtactccgct gacgctgata gccgatccca tagagcagct
     5461 tcttgccaac cgcaccctcg acggacagcc gcgccagctc ctcgagctga tgaaaaagaa
     5521 tgtgcatatc ctgcttcgcc tggtcaacca gatacttgat ttccggaagg tggagaacgg
     5581 gcgcatggag ctccatctcg aaccttttga tttgctcgac agcttccggg gctggaacga
     5641 ctctttccgc atggcgttgc tgaagaaaca tattgctttc agctttgagg catctcccga
     5701 tacggacttc cggatgatgg cggatgcgga gaagatggag cgcatttact tcaatctctt
     5761 ctccaatgcc gtgaagtata cgccggagaa cgggaaaatc accgtacggt tgttaaagtc
     5821 ggaacagaac tacagtctgt ccgtcttcaa ttccggcagc tacatttctt cgaccgatgt
     5881 ggaagccatc ttcgagcgct tctatcaagt ggacgggcat caagccggta ccggtatcgg
     5941 actggcgctg gtacgtgcct ttgtagagat gcatggcggt aacattacgg cacgcagtga
     6001 cgagaaaggc actactttca tcgttacttt cccgcagcag gatgtttcgc agtaccatcc
     6061 caccatagtg acgttgcctg ccgaagagaa ggacgtgtcg tccaccctga tagatacgga
     6121 agtgaaggca tgcgaagagg tggttgaggc tgattgtcct actgtgctgg taattgacga
     6181 taatgcggat attcgcaact atgtgaagtc acttctgtcg aacgagttcc gtgtattgga
     6241 tgctgcggac gggacagagg gtatccggct ggccatgaag tatgtgccgg atgtgattat
     6301 ctccgatgta atgatgcccg gtatggatgg tgtggaatgc tgccgccgct tgaaggggga
     6361 gttgcagaca tgccatatcc cggtgattct gctgacggcc tgctcgctgg acgaacagcg
     6421 tatccagggc tatgatggcg gtgccgattc ttatatttcc aaaccattca attcgcagtt
     6481 gctcttgtct cgtgtccgca atcttattgc aaaccgccgt cagttgaggc agttcttcgg
     6541 agataaccag actatcgaga aggaagccat cagtgatttg gataagggtt tcgtctcccg
     6601 cttcaaatcg cttgtcgagg agaggatgaa agatgcggaa ctcaatgtgg aggatttggg
     6661 acggaatatg ggtatgagcc gtgtgcagct ttaccgtaag ctgaaatcgc tgaccaacta
     6721 ttcgccgaat gagctgctgc gccagatgag gttgaaaaag gctgcctcac tgcttgcctc
     6781 ctctgacatg acggtagcgg agattgccta tgaagtgggc ttttcgtcac cttcctattt
     6841 cacgaaatgc tataaggaac agtttgggga gagtcctacc gagtttctga aaagaagggg
     6901 atagctgttg tctatccccc ttgttcttaa tacacgtctg tttacttctg taaatgatac
     6961 tggaacttat ttcagtattt gaggcaggtt ttcccttccc cagaagtagt aaacacagat
     7021 tccaatccag cttgtgagca ggatgataat tgcaactaat agtttcttca cgccgtctac
     7081 cggccacttc atgatttcaa gtacggcttt gacacacaga accacaccga taatccaaat
     7141 gataaatcca atcataacct gtgatattta gtattgttaa ttaaaaacaa atagagacta
     7201 cgccttattc aggagcagcc tctattcttt atttagtaat cggaattact ctgtaacttc
     7261 agcgccccaa ttttctttgg aaagacgctt gtagctgttg taacgccatt tagcgttttc
     7321 ttcagcagcc ttgaacagct cgtcggcctc ctgcggatat tgcttcatta cggatgcgta
     7381 acgaacttca cccttcagga agtcttggaa tccgctccaa tccggttcct tgctatccag
     7441 cgtgaacgga ttcttgcctt cagcctccag agccgggttg taacgccaca agtgccagta
     7501 accgcactta acggcctttt cttcctctgc ctggctcttg cccatacctg ccttcagacc
     7561 gtggttgata cacggagcgt aagcgatgat gagtgacgga ccgggatatg cttctgcttc
     7621 acggatagcc tttaaagtct gagcctggtc ggcacccata gcgatttggg caacgtatac
     7681 gtaaccgtaa gtagtagcca tcagaccgag gtctttcttg cgtacacgct taccggcagc
     7741 ggcaaacttg gcgatagcgc ctaccggagt agccttggaa gactgaccgc ctgtgttgga
     7801 gtaaacctca gtatccagta cgaggatgtt gacatcctta ccgcttgcga ttacatggtc
     7861 gagaccaccg taaccgatgt cgtaagaagc accgtcacca ccgataatcc actggctgcg
     7921 ttttaccagg tattgagaca gactggcgat agtcttgcag ctgtcgcact tgtctttggc
     7981 agcttctacc atcggaataa tcttttcagc cagttccttg ctcttgtctg catcgtacat
     8041 gttttcaatc caagcctgga atacttcttt gtattcggcc ggagttcctt ctgctgcgat
     8101 ggcatcttcc atagccttca cgatacgtgc gcgcatcttt tcgttggcaa gctccatacc
     8161 cagaccgaat tcgcagaagt cctcgaacaa tgagtttgcc caagcaggac cgtgaccttt
     8221 ttcgttcttg gtataaggag tagaaggtac tgaaccggag tagatggaag aacatcctgt
     8281 tgcgttggct accatttcgc ggtcaccgaa caactgggaa atcagtttaa cgtacggagt
     8341 ttcaccacaa ccggagcaag cgcctgagaa ctcgaacaac ggagtagcga actgagagtt
     8401 cttcacgttg gccttgatgt caaccaaatg ttgtttgctc ttcacgtttt cagcacagta
     8461 ggtccagttg gcagcttccg gcaattggct ttcgaggtgc ttcatagtca gagccttgcc
     8521 acccttcttc gggttgcccg gacagacatc ggcacagttg ccacaaccca gacagtcgag
     8581 aacgtctacc tgaatacgga atgtcatacc gtcgaatgct ttacctacag ccttcagttg
     8641 agtgaagttg gcacccttct gctcttcagc atcgagtacg aacggacgga tggaagcgtg
     8701 aggacaaacg taagcacact tgttacactg gatacagttc tcagcgttcc attcgggaac
     8761 gaatgcggct acaccacgtt tctcatattt ggcagtgcct tgttcccaag taccgtcttc
     8821 aatacccttg aaagcggata ccggcaataa gtcaccgtct tgtgcgttga taggacgaac
     8881 cacttcgttg atgaatgcag gatcgttgtt ttcagccttg gcgtcgtctg ccagattggc
     8941 ccaagccggg tcaacggtca gctgcttgta ttcgccgcca cggtcaacgg ctgcatagtt
     9001 cttgttgaca acatcttcac ccttcttgcc gtaagactta acgatgaact tcttcatctg
     9061 ctctacagcc aggtcaaccg gaataacgcc ggtgatacgg aagaatgcgg attgcaggat
     9121 ggtgttggta cggttgccca aaccgatttc ctgtgcaatc tgggttgcat tgatatagta
     9181 aacagtgata ttgttctgtg caaagtactt cttcaccttg ttgggcaggt tcttggcaag
     9241 ctcttcgcct tcccagatgg tgttcagcaa gaaagagccg ttcttacgca agccgcgggt
     9301 tacgtcgtac atgtgcaggt aagcttgaac gtggcaagcc acgaagtttg gcgtatttac
     9361 caggtatgta gagcggatag gagtgtcgcc gaaacgcagg tgcgagcaag tgaaaccgcc
     9421 tgatttcttg gagtcgtaag agaaataggc ctggcagtgc ttgtcggtgt tgtcaccgat
     9481 aatctttacg gagttcttgt tggcacctac tgtaccgtca gcgcccaaac cgtaaaattt
     9541 ggcttcgaac atgccttcgc cgcccaatgc gatttcttct tcctggggca gagaagtgaa
     9601 ggtaacgtcg tccacgatac cgatagtgaa gtggttcttc ggcatcggca tagccagatt
     9661 cttgtaaacg gcgaggattt gagcaggagt agtatccttg gaacccaaac cataacggcc
     9721 gcctacgata accggagcat tctctgcacc gtagaagcag tcttttacgt cgaggtacaa
     9781 cggttcgccg ttagcacccg gttctttcgt acggtccagt acggcaatct tcttggcagt
     9841 cttgggaacg gcggcaagga agtgcttggc agagaacgga cgatacaagt gaacggcaac
     9901 caaaccaacc ttttcgccat tggcaacgag gtggtcgata gcttcgcggg cagcttccgt
     9961 tacagaaccc atggcgatga taacgcgttc tgcatcttct gcaccgtagt aatcgaacaa
    10021 accatacttg cggcctgtga ttttggaaat ctcgttcatg tattcctcaa cgatagccgg
    10081 aactgcttca tagtagttgt tgcaagattc acggtgttgg aagaagtggt caggattttc
    10141 ggccatacca cgggcaaccg ggttcatcgg gttcaatgca cgtgcgcgga attcagccaa
    10201 agcttcctgg tcgataagcg gagcgaggtc ttcgttctcc aacatttcaa tcttctggat
    10261 ttcgtgagaa gtacggaagc cgtcgaagaa gttcataaac ggaacacggg ccttgatggt
    10321 ggctaggtgg gcaacacctg ccaagtccat aacttcttgt acagaacctt cggccaacat
    10381 ggcaaaacct gtctggcgtg cagacataac gtcctggtgg tcaccgaaga tacacagtgc
    10441 atggcttgcc aatgtacgtg ctgatacgtg gaatacacaa ggcaggaatt caccggcaat
    10501 cttgtacatg ttcgggatca tcagcaacag accttgtgaa gctgtgtaag tagtagtcag
    10561 cgcaccggct tgcagagagc cgtggacggc acctgcagca ccaccttctg actgcatttc
    10621 ctgtaccaat actgtttcgc cgaagatgtt cttgcgacct gcggcagccc attcgtctac
    10681 gtattcagcc atcgtagaag agggggtgat ggggtagatg gcagctactt cggagaacat
    10741 atacgagata tgtgcagcag cctggttacc atcacaagta atgaatttct tctgtttagt
    10801 cataactaaa ttgaattatt tatttaagta aaaaaatctc tctcttaata caagaaaccg
    10861 aataaccaga gaggtatttg gttgcctcgg cctatttctg ccttatgcag tacataagta
    10921 actcccggat tattctttat ctttgttcct tccggacaaa tcttgaaagg catcacctca
    10981 tctaccatga acgagatgtt cttgtcgccc ttgttcacct tgtggtcctt ccacattgtg
    11041 ttggcaaaga aagtgtccag tacgtcttgc tcttccacct tgacgggata gatggaatac
    11101 atcagatttg aattgtgcat cattatcttc gacggcttct tggggaattc ttctcccttc
    11161 ggatagacca tattgatgag tcgtgcgtct gccagatact tgatgtaatt cattactgtg
    11221 gcgcgggagg tctgtatgtc gtttgccagt tggctgacat tcggcgcttt cggcccgtcc
    11281 acggccaaca aatatagtaa tttctttatc ttcgaaaggt atttcagctc aatttgtttg
    11341 atgagcagga tatccacttc caccatcatg ttcatcgtct tgagcagatt ctccgaaaag
    11401 ttacgctttt caaggaagaa agggtagaag ccgtggtgca tatagtcttg tatgtagtcc
    11461 aatggacgta ctttggagag gatgcctttg gctatctgtt cgtggttgct caggatttct
    11521 tccaacggat aggcatggaa cttcatgccc gtctgcaggt ttaggtattc gcggaaggag
    11581 aagccgcgca ggttgtagct cttcacgatg tcgcgcaact ccatattctc ctctttcaga
    11641 cgcatcacgg acgagccggt gaacacgatt ttcaggttgg ggaagcggtc gtagcacata
    11701 cgcagttcct tgctccattc cgggtacttg aatacctggt ctatcaacag cacttttcct
    11761 ccgcggcgct ggaattcggc ggcgaactct acgatgccat gtccggagaa gtagaagttg
    11821 ttcatgttga tgaagaggca ggagcggtct gtgccgaatt tctctttggc atattgcagc
    11881 aagaaagtag tcttacctac gcctcttgtg cctttgatac cgataagacg gtcattccag
    11941 tctatttcgt ccattaggtc gcggcgtacg ggggcattgg tatgctctac gagataagcg
    12001 tgtgtacggt aaaatgcttc catgctttaa attcggttta tcaggcgaca aatatacggc
    12061 ttttttatag atttgcaaag tagagatggc aaaatattat ataactttgc actctcatac
    12121 aaaacgtgag taattggtta acatttgaaa gatgaaactt tatgtgttca atcctgatgc
    12181 agatatggca ttgggaaata atgaagaaaa ttatatggcg cccgctacca tccgccgtat
    12241 ggctgaagac ttggctttgt tgccgatatg gtatgcccag ccgggtagtg gggtactggc
    12301 ctcttccgcc tataatgcag attatctgaa acagatgcaa cagttgttcc ggctggatgt
    12361 gcatttggtg acagagccgg agctgcccga ttatgctgat gtgcgggtaa tgccttgggg
    12421 atggaacccc gctatccgta aacggatgtt gaaaggcggt gttctggaaa aaaatcttcc
    12481 tacgccggat gctttggata aatatcgtat gaaggctgcc cgtagtaacg ctttggcttt
    12541 tcgcgcactt ttctatttca ataaaataga ttatacttgt ggtgacggtt gttgcttggt
    12601 ggaggctgat ggtagaatga cggatatctc tccggatatt gttgatcgtt acaaggaggg
    12661 atgtgtgttc aaatcacttt ggtcgggaag tgaaaaggga ttgtgttggt gccgtaaaaa
    12721 aaaaaaaaaa aatgtttccg attggtgtag tagggcgctg aaagaaaata g
//
