LOCUS       c00021_gnlPro..        14658 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIOFLGIC_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:23:56
            Original ID  :: gnl|Prokka|OIOFLGIC_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14658
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14658
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1182:4658]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1183..4658
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14658
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14658
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             97..1044
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(1183..1938)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="Fer4_7 (E-value: 6.1e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(1972..3918)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201; E-value:
                     1.2e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.4e-61, bitscore:
                     201.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.6e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGYGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQDKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             complement(3954..4658)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_4"
                     /sec_met_domain="SucD_FumR (E-value: 8.8e-132, bitscore:
                     428.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVVCFALVVVV
                     FFIKSLMCSGAC"
     CDS             complement(4821..5723)
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNCM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             5829..6431
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             complement(6514..8127)
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVDKVD
                     EDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVIQPV
                     SNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVDDQL
                     YFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLILDL
                     QGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVDEYS
                     ASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRCIQK
                     PYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRTVYG
                     GGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFNEKF
                     EIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMNSTN
                     QSVQQALKVLNEGIYSTIIQ"
     CDS             complement(8159..8617)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_8"
                     /sec_met_domain="CTP_transf_like (E-value: 3e-18, bitscore:
                     58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(8614..10548)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(10666..11802)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(11953..12987)
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIF
                     LSYTFAIAKRDGSMKEPEKEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVL
                     IYNL"
ORIGIN
        1 acttataact gaatcccgtt tctatttaca caaaattatg gatactgcct aaaaaactga
       61 attacttcta ttttattcat tccccgaaac ttctttatga aagttttcgg ggaatgtttc
      121 ttttatgagt attatttatc tatttttgtc actgcaacaa acaaacaaat ctacttgccg
      181 atgcccaact cttctgcttg cagaggtaaa aaacaatgcg ctcaatgtcc caaggctgtg
      241 gacaatgcaa taatatatgc ttcccacctc agaggattcc atctgccggc gcgaaagtgt
      301 gaggaaaata ttataatttt cctgctgaaa ggagaagtgc ttgtcaacag taaggagtat
      361 gcgggaactg tgttgcatgc aggtgagttc atccttcaag ctattggttc caagtacgaa
      421 atacttgcca tgacggatgt ggaatgcgtt tgttaccggt tcagtaagcc tgaattcttc
      481 tgtgaggacc ggtataacca tattatgaaa gaggttaccc ctccattgat attctatcct
      541 ttgaccatta ctcccgagtt gcagctcttt ctggaaagtt ccaaggccta tttgtccgag
      601 gagaagattt gccgggaaat gctttgtttc aaacggaaag aacttgcttt cattcttgga
      661 aattactact ccgactatga gctttccatg ctgatacatc ctcttgccca gtatactaat
      721 tccttccact actttgtctt gcagaatcat gccaaagtca agacggtaga ggaacttgcc
      781 cagttgggag gatatacagt agctactttc cggcgtatat tcaattctgt ttttcatcaa
      841 ccggtgtacg agtggatgat ggaacggagg aaggaaagcg tggtttatga acttcgttat
      901 acggatgctt ctatatcaga gatttgctat aaatatggct ttgaatcgct gcctcatttt
      961 tccaatttct gcaaaaagaa tttcggggct tctccccgta gcttgcgtgc cggcaattta
     1021 tctgaagtaa acggcatgtc ataaaaaaac tcctccggcg gtttcccggc agaggagtct
     1081 cttgtgatat taatcaaata tagtgaaagc tgagtgataa atctgagctt gctcaaaagg
     1141 tttatccgaa gcgcatccta tattatttgc agaaagaccg gattagtctt tcagtttcgc
     1201 aatgataaag tcgcggttca ggcgagcaat gttgctgatg gaaacattct tcgggcattc
     1261 agcttcgcac gcacgagtgt ttgtacagtt accgaaaccg agttcgtcca tcttgctcaa
     1321 catagccttg gcacggcgca atgcttccgg tttgccttgg ggcaacaggt tcagctggct
     1381 caccttggca gaaacgaaca gcatagcaga accgttctta caagcagcca cacaagcacc
     1441 acaaccgata cagctggcag catccatagc ctcgtcagcg atgggcttcg gaatcaggat
     1501 agcgttggca tcctggggag caccggtacg tacgctgacg tagccgcctg cctgcataat
     1561 cttgtcgtag gccgtacggt cgaccatcaa gtccttgata accgggaaac cggcagagcg
     1621 ccacggttca acagtgatgg tatcgccgtc gttgaaacga cgcatataaa tctggcaagt
     1681 cgtagcgccg gttgcaggac cgtggggatg tccgttgatg tagagcgaac acataccgca
     1741 gataccttcg cggcagtcgt ggtcgaatac aaccggttct ttaccttcag aaatcagctg
     1801 ttcgttcagg atatccagca tttcgaggaa tgaagtatcg cccgggatat ctttcatttg
     1861 gtatgtttca aaagcgcctt ttgctttcgg acccttctgg cgccatacct tgagcgtaaa
     1921 tgatatattt ttatccattt tttttaattc tttaaatgtt caacttcccg attagctctt
     1981 gtagttacga gtctgtacct tgattgcttc gtaaaccagc ggctctttca gcaataccgg
     2041 ttccttttcg tcagaaccct gatattccca gcaagccacg tagaagtagt tttcatcgtc
     2101 acgcttggct tcgccttctt cagtctgata ttcttcacgg aagtgaccac cgcagctttc
     2161 gttacggttc agtgcatcgt aagcaaccag ctcgcccata gtgatgaagt cgtacagacg
     2221 gatagccttg tcgagttcta cattcatgcc ttccttgtcg cccgggatga acagttcttt
     2281 ctcgaactcc ttgcggactt ctttcagctt cttcagacct tccttcaagc cttcagccgt
     2341 acgtcccatg cctacatatt cccacatgat gtggcccagt tccttgtgga tagagtctac
     2401 agacttctta cccttaatat tcatcatcca gtcaatcttg tcctgaacag ccttttctgc
     2461 agctgcaaat tcgggcaggt cggtagagaa acggggaact gtaatctggt cggccaggta
     2521 attctggata gtgtaaggca atacgaagta accgtcggcc agaccttgca tcagcgcaga
     2581 agcaccgagg cggtttgcac cgtggtcgga gaagttacat tcaccaatag cgaacagacc
     2641 cttgatggag gtcatcagtt catagtcaac ccagataccg cccatggtat agtggatagc
     2701 cggataaatc atcatcgggt tttcgtatgg gctgacatca gtgatttctt catacatatc
     2761 gaagaggttg ccgtaacgtt gtgcaacgac atctttaccc agacggttga tagcttcgga
     2821 gaagtcaagg aatacggcaa ggccggtgtt gttcacgcca taacccttgt cgcagcgttc
     2881 tttggctgcg cggctggcaa cgtcacgcgg aacgaggtta ccgaatgctg gataacggcg
     2941 ttccaggtag tagtcgcggt cttcctcggg aatatctttt ccttgcagtg taccttcctg
     3001 cagtttcttg gcatcttcca gcttcttcgg aacccagata cgaccatcgt tacgcagaga
     3061 ttcggacatc aaagtcagct tagactgctt gtcaccgtga accgggatac aagtggggtg
     3121 aatctgtacg taagcagggt tggcaaacca ggcaccttta cggtagcaag ccattgctgc
     3181 agagcagtta catgccattg cattggtaga aaggaagtag gcattgccgt aaccaccggt
     3241 agcgattacc acagcgtggg cggcaaaacg ttccaattta ccggtaacga ggttctttgc
     3301 aatgataccg cgggcacgtc cgtcaatgag gacaacgtct tccatttcgt agcgggtata
     3361 cagtttcaca gtgcctacgt tcacctggcg gctcaatgca gagtatgcac ccagcaacag
     3421 ctgttgtccg gtctgaccct tggcatagaa agtacgggat acctgagcac caccgaaaga
     3481 acggttgtcc agtgtaccgc cgtattcgcg ggcgaaagga acaccttgtg caacgcattg
     3541 gtcgataata ttgttggata cttcagccag acggtaaacg ttagcttcgc gggcacggta
     3601 gtcgccaccc tttactgtat cgtagaacag acggtataca gagtcaccgt cgttttggta
     3661 attcttagca gcattgatac caccttgtgc agcgatggag tgtgcacggc gcggagagtc
     3721 ctggatgcag aagttgaata ctctgaaacc catttcgccc agagaggcgg cagcactggc
     3781 accggcaagt ccggttccta ctacgatgat gtccagacga cgtttgttgg cagggtttac
     3841 taatttttgg tgagccttat aattggtcca tttctcagcc accggtcctt ccggtatttt
     3901 agaatctatc ttagtcataa tgctattaca atttaatcat ttacaataat ttatcagcaa
     3961 gcgccgctgc acatcagtga tttgatgaag aatacgacaa ctaccagagc gaagcataca
     4021 acaacgatag tggagtagat gttggagata catttccaac ggttgatcca tactttgttg
     4081 ttccagccca aagactgcat ggagctccag aaaccgtgag tgaggtggaa ccacaatgcg
     4141 cccagccaaa cgaggtaaag cactacgaat accggattgc tgaaggtgtt ttgaatgtga
     4201 tagacaccgt tggctgcata tgccagcgtg agggtgtcgg catgcatgcc catgttgtgc
     4261 atcaactcgg gaagctgcat tttagcccag aagtttacca ggtgcaggcc caaacccacg
     4321 attacgatga tacccagtac gagcatgttc tgagaagccc attccacagt cttgggcttt
     4381 tccgtaacgg catagcgttc gctaccacgt gccttacggt tctgcatagt cagccagaaa
     4441 gcgtagatga tgtggatgat gaataaggca gccagaccta ccgtagccac caatgcgtac
     4501 cagtttgctc ccaggaactc acaaaccatg ttgtagccat tagccgagac taatgcaacc
     4561 aggttcatcg ccatgtgaaa tgtcagaaac aggacaaggg cgataccggt aacgctcatc
     4621 accactttcc ttcctacaga tgaattactt aaccacataa atgattgaat ttaagttatt
     4681 taatagtttg aaaatttgtt ctatcaggat acttctgtaa atgtttcgca aaaataggag
     4741 aaatccagcg ataaagcaag cgattaaaga aataattccg taatccggca gaatgcgaag
     4801 tttacggaca agtaaaaggt ttactcgtcc tcctggtctt tgccttgctc tttgcagata
     4861 atggaaatct tttctccgtt tgccgaacgt tttctcaggg cgcggggcgt gtctccgaaa
     4921 gagtctttgc agaagtgggc aaagtgggat agggaatcaa agccatagcg ggcgctgatg
     4981 actgaaatgc gttgtttggt gtattgcagg tcgttcagaa ttccttcacg tttcttgtcc
     5041 agaatccatt catagaccgg gaccccatac atatttttaa acagacggcg gaatgtggtg
     5101 gtggtatatc caccgaggtg ggcaaactct tccacattct tcaccttgtc gtagttctgc
     5161 atgacgaaat attggaagct ttccgtataa gtgctgatgg ggtagaagaa tgtactgatt
     5221 tggtgtagcg gatagtagca tgtcaatatg tataccaatt cctggcattt catttcaatg
     5281 tatttgctgc acgcataggg ttgctcgttg aggtagcagg caaggctttt caggagccct
     5341 tcgagcatgg aaatcgcggt aagcggggta taagtcaagg gggcttccga gcgtttcagt
     5401 atctccttgt agcgctcttc gcaaatcaga ggaagctcgg tgaaccaata gacaatatat
     5461 tccacttcgg tcaaagccag gagttctact ttggagccga tggcttgcaa gatgagctgg
     5521 cggctttgga gagtggtgcc cggatattcg tcactgttta caagtaattc acctttcagc
     5581 ataaatatca tgcagttctg tgtgcacttt tcagcagaga aatgttgtcc cttggggtag
     5641 tggcggtaaa ccaatactcc ttctgatttt tggggacata ccatacaatc aatctgtcgg
     5701 ttgcagcaag tttccagtct catgaaatga ttagcgaatt attataaatg tggcaacaaa
     5761 gatagaattt ttttgtgaaa actctatcta tttgtcctat ctttgcgtca aactaatata
     5821 aaggacttat gaaaaaggct attttttttg tatattttat ctgccttgtt gtatccggtc
     5881 tttcggcaca gaattgggat attaacactt tgcatcgggt taacagttgg gatggcaagt
     5941 ttgtccgtaa ctataataag ataatttcac gttcggagcc ctatgttgct gtcggtgttc
     6001 cggtggcgat ggcggttgcc gcttggataa aacatgataa gggtttgctg aaagatgcgg
     6061 tctacgtagg tacaagtgta gcgggggctt ttgttgtgac ttatggaatg aaatatctgg
     6121 tggaccgtga gcgtccttat gataaatatc ccgacagagt gcatgcatat agccatgaag
     6181 gcagcccgtc ttttccttcc ggacatacgg cgacggcttt tgcccttgcc acctcgctca
     6241 gtgtaaagta tcctaaatgg tatgtgatag ctccgtctgc cctgtgggct tgttccgtgg
     6301 gagtttcccg tatgaacgag ggagtgcatt atccgtcaga tgtgttggcg ggggctgcaa
     6361 tcggtgctgg atgtgctgtg gtcaacatct acgtcaacaa gtggctgaat aagtggctgt
     6421 tcggagaatg attttaggcg cgaattacgc ggaatacgcg gagttagata aactaaatcc
     6481 gcataatccg cgcctaagtt tgtttcaagt cggctattgg ataatagtgc tgtagatgcc
     6541 ttcgttcagc acttttagag cttgctgcac gctctggttc gtgctgttca tcacctggaa
     6601 gtattcgttc atgtcccata ggtcacgggc tatcaaggct ttaagttgtg tcttgatgag
     6661 cggtagggat tggttgtact gtttctcgtc aaacttgatt ttctctttgt cggcaagcgt
     6721 acgtatttcg gcaaggaagt tatcgtctat ctcgaacttc tcgttgaagg cttcgaattt
     6781 cttgtatttg ttctgcaact ccttccggtg cttctcgatg tagccggtag tggctttgat
     6841 aaccacgcct ttggctacga ggttgcggtg atagtctgtg tactgggtag tgtcgatggg
     6901 gacgaagaag tcgggcatga tacctccacc tccgtaaacg gtacgtccca tacgcttggt
     6961 ctgtgctttc agggagtcgg caaaatggat actgtccgca tgaatcattt ctccatgatt
     7021 gaagcggtct atcagttcct ggttatactt atcctgactg ttctcgccgg ttaggcggcc
     7081 gtcgaggttg gcggtgctgt cgtaaggctt ctggatacaa cggcccgaag gagtatagta
     7141 gcgggcgata gtgaggcgaa tcatggaacc gtccggcagg tcgataggac gctgtactaa
     7201 tcccttgccg aaggtgcggc gtcctactac cacgcctctg tcccagtcct ggatggctcc
     7261 ggtcacgatt tcactggcag aagcggagta ctcgtccacc aatatgatga gacggccgtt
     7321 cttgaagttg cccgtacctt tggcaaagaa atcactgcgg cgtgcggccc ttccttcggt
     7381 gtagacgatg agttcttttt gcttcagaaa ttcgttggca aggtcgatgg cggcattcag
     7441 ataccctcct ccatttcctt gcaggtcgag gatgaggtct ttcattcctt tcttttgcag
     7501 gcttttcagg gcttctgcaa actcttcggc ggtggttgcc ccgaagcggt tgatacggat
     7561 atagccggtt ttgggttgta tcatgtaaga tgcgtccagg ctgaggatgg gaattttgtc
     7621 acgcttcacg gtgaagtaca gctggtcgtc cacgccacgg cgcacgatgg tgagtttcac
     7681 ttccgagtct ttcggtccgc gcaggcggct cataatatct tccgtgctca tttttactcc
     7741 ggcaatggcg ctgtcattga cggctacgat acggtcgccg gcaaggatgc ccaccttctc
     7801 ggaaggtccg ttgctcacgg gttgtatcac aagcagggta tcttctatca tctgaaactg
     7861 tacgccgatg ccctcgaaat tgccttgcaa cggctcgttc atcttcttca cttcttcggc
     7921 gttgttgtag gtggagtgcg ggtcgagttg tgccagcatc ttgatgatgg cttcttccac
     7981 cagcttgtct tcatccacct tgtccacata aaggttggtg atggcaaact ctgccatttg
     8041 cagtttgcgc agggcttcat tgttcggctt ttgcgcttgt gccgtcaccg cgcatataca
     8101 tattataata gtaaatagtt ttttcatcat ttccatttta atccctaatc ctttatcctt
     8161 aatccctaat ctccattccc tccggtatga acatgcttat gtccttgccg tattgcagca
     8221 gttcgcgcac ggtggtggaa ctgacgcagg taagttccgg ctcggtgaag agcaggatgg
     8281 tttctatgcc ggtcagtttg cggttgatgt cggcaatggt ttcctcgtat tcgaaatcct
     8341 tcacggtgcg tatgccgcgt attatcagac tggcatctac ctgccgggca aagtcgatag
     8401 tcaggcagtc ataggactgc acaatgatgc gcggctcgtt ccggtagtag tctcgtatca
     8461 tttgttcgcg cttttccaag gggaaatacg tattcttatt ttcattgatg ccgatgccta
     8521 tgacgatttc gtctataaaa gtcagtgcac ggctcactac cgaagagtgt ccgatagtaa
     8581 acgggtcgaa tgttcccgga aagatagctc ttctcatgat gccaaatctt cttctataac
     8641 caagttgttg ataataaagt tttgtcgttc catggtattc ttacccatgt agaattccag
     8701 cagctctttt acgaggtctg tcttgcgcag ggacacttgt tccagacgca tatccttgcc
     8761 gataaaatgc ttgaactcgt cgggcgagat ttctcccaga cctttgaatc gggtgatttc
     8821 ggggttggga cccagttctt caatggcttt cacacgttcc tcctctgtat agcaataact
     8881 tgtcttcttt ttgttgcgca cgcggaagag aggggtttgc aggatatata catgcccttt
     8941 ctttatcagg tcggggaaga actgcaggaa gaaggtgatg atgagcaggc ggatgtgcat
     9001 gccgtccaca tcggcatcgg tagctacgat gactttgttg tagcgcagtg tctctatgcc
     9061 gtcttctata ttcaaggctg cttgaagcaa gttgaattct tcgttttcat aaactacttt
     9121 cttggtgagt ccgtaggaat ttagcggttt accacgcagg ctgaatactg cttgggtatt
     9181 cacgtcgcgg ctcttggtga tggaaccgct ggcggagtct ccctcggtaa tgaagatgca
     9241 ggattcggtt tcctggtctt tgcctttacc gtcactcaag tggtagcggc agtcgcgcag
     9301 cttgcggttg tgcaggttgg ctttcttggc gcgttcgcgt gccagcttgg tgacgccggc
     9361 aatggctttg cgctctttct cggagtcttg tatcttttgc agcatcactt cggccacaag
     9421 cgggttcttg tggaggtagt tgtccacttc cgtcttgatg aagtctccta cgtatttgtt
     9481 caccgtgggg ccggcgggct tgtgttcctg cggcgcggca ggccacatgt tgttgctgcc
     9541 cagtttcgtt ttggtctggc tctcgaacat gggttcctcc acgtcgatgg caatggcggc
     9601 taccagtccg ttgcggatgt cggcatattc ctggttcttg ttgtagaact ccttgatggt
     9661 acgggcaatg tgttccttca aggcagtctg gtgtgtgccg ccttgggtgg tgtgttgccc
     9721 gttgacaaag gagtagtact cttcgccgta ttggttggtg tgtgtgaagg caatctcgat
     9781 gtcctctcct ttcaggtgga tgatgtcgta aaggccttcg ctggtcatgt tgtctttcag
     9841 caagtcctcc agcccgtggc gggaaacgat gcgctggccg ttgtaaatga aggtgaggcc
     9901 cgtattcagg taggtgtagt tgcgcagcag ggtttctacg aactggttct ggaaggaata
     9961 gttcaagaag agtgtggcgt ccggttcgaa gaagatatag gttccgcttt cttctgtcga
    10021 gtcttcggtc acatcactca acagcgttcc tttttcaaag atggcgatac gtaccttgcc
    10081 gtcgcggtag ctgcgtactt cgaagcggct gctcagcgca ttgactgcct tgatacctac
    10141 gccgttcagt ccgacacttt tcttgaaagc cttcgagtca tatttacccc cggtattcag
    10201 tttgctgacc gcctctacca gtttgccttg cggaatgcct cgtccatagt cgcgtacgct
    10261 gacacgcaga ctgtcttcta tagtcacttc tatacgcttt ccggcaccca tcttgaactc
    10321 gtcgatgctg ttgtccatca cttctttcag caacacatag atgccgtcat cgttctgtga
    10381 gccgtcgccc agacggccta tgtacatacc ggaacggaca cggatatgct ccatgtcgtc
    10441 caggtggcgg atgttgtcgt cggtatattc cacgctggaa acggggctct ctgtgatatt
    10501 gttgtctgct tcttccagcg gcagggtcat attgttgtta tcttccataa gtacgttatt
    10561 ccttcatatt gcgcattgcg acaaaggtaa tgagaaattc gggggttcgc aaaaaaataa
    10621 tgtcttttat ggacttctga caagcttata ttctggattt agaacttatt ttattccttt
    10681 cacaaagcat cttctccgtt tatgctgttc cgtcttgaag tactcccact gcgcttgcac
    10741 cttgccgttc agctccagct ccggattact ctcggcatac tcgaaaccaa gttgctgata
    10801 gacggggata aggtcggaga acaacaatgc atttaccccc ttgttctgat actccggttt
    10861 cacggcaacc agcagcaaat cgagcatctt gggatatttc ttcaagaaga tggtcttggc
    10921 caggtgatac caacccatag gaagcaggcg cccgtgggct ttttgcaacg cttcggcgag
    10981 tgacggcatg gaaatgccta cggcaagcag ctggtcatcg gcatcggtaa tcaatgtcac
    11041 catgcgtagg tcgaggatgg gcaggtacat cttgacgtat tggtcaatct gccgttggct
    11101 cagtgcagaa tagccataga gtggctgata ggcttcgttc atcagttcga agatggcctg
    11161 accgtagtct tgggcaatct tcttggcaga tgtgtatttc tttaccttga ggttatactt
    11221 gcgctggatg aggtcggaga tgcgcttgtg cttgtcgggt atggcgtcgg gaatgtagat
    11281 tttgtactcc acccaatcgg catccttctc aaagcccatg cgttccagat gttgcggata
    11341 gtagggatag ttataaatgg tggccatggt gctgagctgg tcgaatcctt cgatgagcat
    11401 accttcggca tcgaaatctg tgaatcccag cgggccttgt atatgtgtca ttccccgttc
    11461 ttttccccat tcttccacgg tgcgaatcag ggcatcggag acttccgcat catcgatgaa
    11521 gtctatccag ccgaagcgga cttccttttt gttccaggtt tggtttgcct tgtggttgat
    11581 gatggcagct acacgtccta cgattttacc ttcccgataa gccaggaaat agtcggcttc
    11641 acaaaattcg aatgcagcgt ttttcttctt gttgaaggtg ttgagcatgt catcgaaaag
    11701 gtcggggacg gaataagggt tgtttttgta tagcaggtag ttgaaacgga taaagcgctc
    11761 cagttcccgt cttgtggtta ctttcttgat tgtaattgcc atagttgttc aatattgaga
    11821 ccacaaaggt aatgcaaact gagagcagaa caaaataagc ttgcttattt tttatgccga
    11881 ggtacagctt gccttattta aaaatacgtg ataatcttta aaataccgcg tagggtgttt
    11941 gtaaatttgc tgttagaggt tgtatatcag taccgctgtg taggcaatgt agcagagaat
    12001 cagaatgctt ccttccaccc gggtgatgat gcgtttcccg aaaaagatac cgaacagcca
    12061 aagcaggatg ctggacccta cgagtaccca caaatcgaaa ttggtgatgc ccgtcagacg
    12121 cagtggagtg atggaggccg aacaacccag tacgaagaat atattgaaga gattacttcc
    12181 gatgacgttt ccgatggcta tttcggggtt tttcttcaag gcggctacga tggaggtggc
    12241 gagttcgggt aatgaagtgc cgcctgctac gagcgtgaga ccgatgatgg attcgctgac
    12301 acccaatccg cgggctatgc cgctggcacc gtctacaaag aaattacctc cgatgatgag
    12361 gccggcaagt ccgccgagaa tgtatagggc ggatttccac gcgggtaaca gcctgatttc
    12421 gtcttcttcc tgtaagtgct ccttttccgg ttccttcata cttccatccc tttttgcaat
    12481 ggcaaaagta taactcagaa aaatggtaaa gaagcatagc agcaataggc cgtcggtgat
    12541 gctgagtatg ttctccccac tgctgtccag taagacgtcg ttggcacaaa tcagcagggc
    12601 gaaggatgaa aggatgcaaa ggggtatttc gcgtttcagt gtgttacggg taatggctat
    12661 cggggcaaaa agggccgtac aacccacaat catcagggta ttgaacgtat tgcttcccac
    12721 cacattgccg atggcaatgt ctgcactgcc ttttagggca gaggatatgc tgacggtgag
    12781 ttccggtgcg gaagtaccga aggcgacaat ggtaagcccg atgacgatgg acggtatatg
    12841 gaaacgtttg gcaacggatg cggcaccgtc tgtcaagcca ttggcaccca gaagaatgag
    12901 gagcagtcct ccgacaagaa acaatatatc cataggtatg tcaattttga gtacaaagat
    12961 aatgcaaacc ggatacagaa ctttcatgtt tgcatgaaaa agttatgttg attaggatag
    13021 gaagttaaaa acattccgta tgtttgaagc atttattggg tatatttgca taattaaaga
    13081 atcaaatcaa gaagtttata tatgaaggtt atccgtgctt tctgtctttg ttggctgttg
    13141 atgctggcag acggagtgtc agctcagttg gtagataaag tgctcagtgt tttaggtgag
    13201 gatagtgtgg ggagtgtcac agtggcaagg actgactccg attcgattca gttgtcgctt
    13261 gtccggcagg agttggaaac agcccggctg aatgaggcga acctgcggat ggaaatggag
    13321 cagatgaagt tggcgggcta tgcggccgat tcggtgaagc tggcattgca gaaacaacgc
    13381 attgattcgt tgcggacggt gacaccgggt attccggtgg tggtggagaa ggacactttg
    13441 ttctatctgt atgccaagcg tggagggcat acgccccaac agcgagccaa agatgtaagc
    13501 aacgtcatcg aagcattggg cacgcgtttc aatctgcgtc cggactctgt ttatttagag
    13561 agtacggata ttgttacaga cttgatgtat ggcgaaaagg tcatcatttc ctttaccgat
    13621 caggatgctt tgtgggaaaa ctgtacccgc gaccagctgg ccgccagcaa gaggcatgtc
    13681 gtggtggaca aactgaaagc catgcagaag gagcatagct tgtggcagtt gggtaagcgt
    13741 atcttgtact ttatcctggt gcttgtggga cagttcttct tgttcaagtt taccaactgg
    13801 ctgttcagaa aactcaaact acgcattcag aagctgaagg ataccaagct gaaaccgatc
    13861 tctattcagg attatgaatt gctggatacg cagaagcagg tcaacctgct ggtgtttgtt
    13921 gccaacctgg tgcgttatgt agtcatgctg ttgcagttgc tgctgacggt tccgttatta
    13981 ttctccattt tccctcagac caagagcttg gcttatacat tattctccta catctggaat
    14041 cctataaagg tcatcttgaa tggaatagcc gactatatac ccaatctgtt cactatcttt
    14101 gtgatatgct atgcggtgaa gtatctggtc agactggtgc gttatcttgc caatgaggtg
    14161 caggctgaac ggctgaagat aaacggcttc tatccggatt gggccattcc tacctatcat
    14221 attgtgcgct tcttgcttta tgcgtttatg attgccatga tttaccctta tctgccgggt
    14281 tccaagtcgg gagtcttcca gggaatctcc gtgtttgtcg gcttgattgt ttcgctcggt
    14341 tccagtacgg ttatcggcaa tatcattgca ggactggtca taacctacat gcggcctttc
    14401 aagctgggtg accgcatcaa gctgaacgat actacgggca acatcattga gaaaacaccg
    14461 ctcgtcaccc gcatccgtac tccgaagaat gaggtggtga ccattccgaa ctctttcatc
    14521 atgtcttccc atacggtcaa ttacagccag tctgcccgtg agtatggatt gattatccat
    14581 tcggaggtca gtattggcta cgatgttccg tggcggaaga cacatcagct gttgatagag
    14641 gctgcattga atactcct
//
