LOCUS       c00086_gnlPro..        10456 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKNONHNB_86.
ACCESSION   c00086_gnlPro..
VERSION     c00086_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:04:47
            Original ID  :: gnl|Prokka|IKNONHNB_86
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10456
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10456
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[164:6106]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      165..6106
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10456
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10456
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             165..1124
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.9e-113, bitscore:
                     368.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIELFLSCGRCEPCRRYYRYYE"
     CDS             1078..1956
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-93, bitscore:
                     302.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEDVNRAGGIIGIMNELVKAGLVDGSVKRADGLTLNEAIDQYCIT
                     SVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELDTDRATGCIRDVEHAYVKDGGLAVL
                     YGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDAACEGILKDQVVSGDVVVITYEGPK
                     GGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGGTSGLSIGHISPEAAAGGAIGLVKD
                     GDIIEINIPERTIHVKVTDEELAKRREAEEARGTKAFTPPFRQRTVSKALKAYAKMVAS
                     ADKGGVRIVED"
     CDS             1983..3683
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             3696..4250
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_4"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             4287..5018
                     /locus_tag="ctg86_5"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             5060..6106
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_6"
                     /sec_met_domain="IlvN (E-value: 9.8e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             6608..9883
                     /locus_tag="ctg86_7"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVNLRVYVTGNNLLTFG
                     PAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             9902..10456
                     /locus_tag="ctg86_8"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSD"
ORIGIN
        1 agatgatgaa caatgtattg catattattc tcgtggtggt ccttctagtc attagtaggt
       61 aaggagaaag gtgtgtaaga agttgtgaag tcgtaaaaga tatttcttaa gcctttctcc
      121 atatagggaa aggctttttt attgactaaa agataaaaac agatatgatg aagaatccgt
      181 taagaagctc ctatagcaca gaaggcagac gtatggccgg agcccgtgca ttatggcgtg
      241 ccaacggcat gaaagaagaa cagttcggta aaccgatcat tgccattgtg aattcattta
      301 cccagtttgt accgggccat gtgcatctac acgagatcgg acagcaggta aaagcggaaa
      361 tcgaaaagct cggttgcttt gccgcagaat ttaatacgat cgctattgat gacggtattg
      421 ctatgggaca cgacggaatg ctttattctc tgccttcccg cgacatcatt gctgacagtg
      481 tggaatatat ggtgaatgcg cataaggctg atgcaatggt ttgtatcagt aactgcgaca
      541 agattactcc gggtatgctg atggccagta tgcgtctgaa tattccgaca atctttgtat
      601 ccggcggtcc gatggaagcc ggtaatctgg acggacgtgc actcgatttg atcgacgcca
      661 tgattgaagc ggctgacgat tctatcagcg atgaacaagt agaaaaggtg gaacgttccg
      721 cttgcccgac ctgcggttgc tgttctggta tgttcacggc taactctatg aactgtctga
      781 acgaagcgat tggattggct cttcccggca acggaacagt tgttgcaaca catgccaacc
      841 gtacccgcct gttcaaaaaa gccgcgaaga tgattgttga taatgccttt aaatattatc
      901 gtgacggcga tgattccgta ttgcctcgca gtattgccac ccgtcaggcc tttctgaatg
      961 ctatgtcgct ggatattgcc atggggggat cgacgaatac agtccttcac ctgttggccg
     1021 tggctcatga agcggaagtc gattttacaa tgaaagacat cgagttgttc ttatcatgtg
     1081 gaagatgtga accgtgccgg aggtattatc ggtattatga atgagctggt aaaagccggt
     1141 ctggtggacg gttccgtgaa acgtgcggat ggtctgactt tgaatgaggc tatcgaccaa
     1201 tactgcatta cctctgtaaa tgtaacggaa gaagcaatca atatttataa aagtgctccg
     1261 gcccaccgtt tcaatctggt gctcggatcg caggaaagtt attataaaga actggatacc
     1321 gaccgtgcaa ccggatgtat ccgcgatgtg gaacatgctt atgtgaaaga cggcggtctg
     1381 gctgttctgt atggaaatat tgcacaggac ggttgtgtgg ttaaaacagc cggggtagat
     1441 gaaagtatct tccgttttgc cggccctgcc aaagtattcg attcgcagga tgccgcttgc
     1501 gaaggtatcc tgaaagatca agtcgtctcc ggcgatgtcg tcgttatcac ctatgaaggt
     1561 cctaagggtg gtccgggtat gcaggaaatg ttgtatccta cctcttatat aaagagtaaa
     1621 catctgggta aagaatgtgc gttaatcaca gacggacgct tcagcggtgg aacatcgggt
     1681 ttgtcaatcg gacatatttc tcccgaagcg gctgcaggcg gagcgattgg cttagtgaaa
     1741 gacggcgata ttatcgaaat taatattccc gaaagaacca tacatgtaaa ggtgacagac
     1801 gaagaactgg ccaaacgccg tgaagcggaa gaagcccgcg gaacaaaagc ctttacacct
     1861 cctttccgcc aacgtacggt atcgaaagca ctgaaagcat atgcaaagat ggttgcttcg
     1921 gccgataagg gcggtgtacg aatagtagaa gattaataaa caccaaatac tatattttag
     1981 agatggacaa acaaaagata accggttcgg aagctttgct gaaagcgctg atcgctgaag
     2041 gagtagatac tatcttcggt tatccgggtg ggcaggcgat accaatttac gatagtttat
     2101 acgattacag agatcagtta aaacatattc tggtgcgcca cgaacaaggt gcaacacatg
     2161 ctgcacaggg atatgcccgt gtttccggaa aagtgggagt aacggtggtt acttcgggtc
     2221 ccggggcaac caataccatc actggtattg ccgatgcgct gatggacagt acaccgatgg
     2281 tggtgattgc cggccaggtt ccgtctccgc tgcttggaac agatgctttc caggaagttg
     2341 atgtgatcgg tatcacacaa ccgattacca aatgggctta ccagatacgc cgcccggaag
     2401 aaattgcttg ggccgtttcc cgtgctttct atatcgcatc gaccggtcgc ccgggacctg
     2461 tggtactgga tttggcgaaa gatgcacagg tgggtttggt agattatgag tatcagaaag
     2521 tggattatgt tcgtagttac caacctgaac cggatatcag ggaggaacgt atcgaggcgg
     2581 ctgcttcatt gataaataat gccaaaaagc cattctgtct ggtagggcag ggggttatcc
     2641 tgggaggagc tgaagaagaa ctgaaagaat tcttgttgaa aaacgatata ccagccggtt
     2701 ctaccgtatt gggcttgtct gcattacctt cggacttccc attaaataaa ggtatgttgg
     2761 ggatgcatgg aaatgtcgga ccgaaccgca agacaaacga atgtgacgtg ctgattgcta
     2821 tcggtatgcg tttcgatgat cgcgtaaccg gcgacctgaa gacttatgcc aagcaggcaa
     2881 agattatcca cctggatatc gacaattcgg agatcggaaa gaatgtgccg gtcgacgtga
     2941 aagtgctggg aaatgccaag catacgattc cgatgattac ggctttactg gaagaacgga
     3001 agcgtccgga atggaatgct gaattcgaac cggatgaaaa agaggaatat aataaggtaa
     3061 tagaaaaaga actctatcct accgaaggcc aactgaaaat gggcgaggta gtccgtaagg
     3121 tttccgaagc aaccgataat gatgcgattc tggttacgga tgtaggtcag aaccagatga
     3181 tgggtgtccg ctatttcaaa tataaacaaa cacgcagcgt agttacttca ggaggtttgg
     3241 gaacgatggg ctttggcctt cccgccgcca ttggagcgaa gctgggagcg cctgaccgta
     3301 cggtctgttt ctttaccggc gacggtggta tccagatgac tatccaggag ttgggaacta
     3361 tcatgcagga aaatctgaat gtaaagatca tcgttcttaa caacaatttc ctgggaatgg
     3421 tacgccagtg gcaggagctg ttcttcaacg aacggtattc gaataccatc atgaagaatc
     3481 cggattttgt agcgatagcc aaggcttttg gtattgcttc ccgtgcggta gataaacggg
     3541 aagacttgga tgaggcgatt gctgaaatgt tgaatcacga tggtgcctat atgttggttg
     3601 ccaatgtgga aacttgtggt atggtatatc cgatggttcc ggccggagga agcgtgacaa
     3661 acatgatttt gggtgataag taaggaggag aaactatgaa tacaaaacaa ttatataccg
     3721 ttattatctt ttcggaaaac actgttggtc ttctgaatca gataactgtt atctttacgc
     3781 gccggcaact gaacattgag acgctttctg tttctccctc tgctataaag ggaatacata
     3841 agtttacaat tactaccttt gccgacgagg atacgatcga caaggtcgta aaacagatcg
     3901 acaagcgtgt ggatatcctg aaagcctatt ataatacgga tgaagacctg gtttaccagg
     3961 aaatcgctct ttataaactg agtaccgaac tctttatcaa gatggggacg gttgaggatc
     4021 tgatccgtaa gtacaatgcc cgtatccttg aaatgaatga ggattgtgtg gtgttggaaa
     4081 agagtggtca ttatgatgag acacaggctt tgtttaaaga attgagtgag acgatcggtg
     4141 tcctgcaatt tatccgttcc ggacgcgttg ctataacgaa gagtaaggta gaacgtctga
     4201 gcgacatgtt atctgcaatg gaaaagaagt tgcaggaaaa acatgtctga gaataataag
     4261 gaaacatttt gtaaataaag taaattatgg agaagaacaa agtaggagaa tttcatttcg
     4321 taacagagtc ttatctgacg gacttccggg gacgtattac aatccctatg atcggaactt
     4381 atttgttgca tgctgcttct tgccatgccg ccgaccgtgg attcggatat aacgatatga
     4441 ccgaaaggca taccgcctgg gttctttccc gtctggctat cgagatgact tcttatcctg
     4501 ccatgtctga atccgtaact ttatatacct gggtggatga ggtcggtaag ttgtttacca
     4561 gccgttgctt tgaactggtg aacggcgaag gcaagacctt tggctttgcc cgctctatct
     4621 gggcggctat cgatatggaa acccgccgcc cgaccttgct cgatgtggag ggcctgagtg
     4681 cttatatcac cgaccgtccc tgtccgattg aaaaaccggg taaaattgct ccggtggaaa
     4741 acaacacttc cggcgaacct taccgtgtga agtatagtga cctggacgta aacggccacc
     4801 tgaacagtat caaatacatg gaacacctgc tcgacttgtt cgatatcagt ctgttccgag
     4861 aaaaagagat aagccgtttc gaaatagctt atcagtccga aggaaagtat gggatggagc
     4921 tgactctcca taaccaggaa gtatccctcg ataaatataa tatggcaatc tgtaacgacg
     4981 gcaaagccat cagccgcgct gccgttacct ggatctgaaa aacaaattat tttatataca
     5041 ttttaatagt aaaaagaaaa tggcagtaat gaattttggc ggtgttgacg aaaacgtagt
     5101 aacccgcgaa gaatttccgt tggaaaaggc aagagaagta ttgaaagacg aaacaatcgc
     5161 tgtaataggt tacggcgtac aaggtcctgg ccagagcctg aacctgcgcg acaacggttt
     5221 taacgtaatt gtaggacaac gtaaaggtgg taagacctgg gaaaaggccg ttgctgacgg
     5281 ttgggtaccg ggcgaaacac tgttcgatat cgaagaagca tgcgaaaaag caactatcat
     5341 ccagtatctg ctttcagatg ctgctcagat tgaagtttgg ccgcgcatca aaaaatacct
     5401 gactccgggt aaggctttgt atttctctca cggattcggt atcacttaca aagaacgtac
     5461 aaacatcatc cctcctgctg atgtagacgt aatcctggtt gctccgaaag gttcaggtac
     5521 ttcactgcgc cgtatgttct tgcagggtcg tggtctgaac tcaagctacg caatcttcca
     5581 ggatgcaaca ggcaaagcat gggatcgcgt gattgcactg ggtatcggtg ttggttctgg
     5641 ttacttgttt gaaacaacat tcaagaaaga agtttattct gacctgaccg gcgaacgtgg
     5701 tactttgatg ggagctatcc agggattact gttggctcag tacgaaactt tgcgtgaaaa
     5761 cggtcacgaa ccttctgaag cattcaatga aacagtagaa gaactgactc agtcattgat
     5821 gccgttgttc gcagaaaacg gtatggactg gatgtatgca aactgttcaa caactgcaca
     5881 gcgtggtgct ttggactgga tgggcccgtt ccacgatgct acaaaaccgg tgttccagaa
     5941 gttgtatagc gaagttgcct gcggtaacga agcacagcgt tctatcgaca caaacagcaa
     6001 gcctgactat cgtgaaggtc tggaaaaaga actggctgct cttcgcgaaa gtgaaatgtg
     6061 gcgtgcaggt gctgttgttc gtaaacttcg tcctgaaaac aactaataaa tggtgataca
     6121 ttaatagtta aacattttgt gatataaaaa cggcaatccg gcttttcggg ttgccgtttt
     6181 tttatggttt atgtaatgcg ttaatggtta aaaaatgttt ttgattgcaa ctgttattga
     6241 tttttcatcc caatatgtat gtcattgttt gaatgtggat tttagataaa aaaatcaatt
     6301 aaatggtggt taaaatatat ttattagagc aataaatata cataattatg cttgtattaa
     6361 ataatgataa gttatatttg ctgatggaga tactgtagtt tgtagagtgg aaatatagaa
     6421 ggatgttgtg tgtaatgatc agtatatctt tgttttagtt aactttattt tattgaaatg
     6481 tatgccagtc acttttatct tagaaaagtg taacctctaa tgaaatgaac gctattgtga
     6541 ttaattttat ttaattaaag acttgaattt agctatgtgg accaactcaa aactaattag
     6601 atcactaatg atttctgtat tattaggtgc ggcaggtgcg attgctgcca atcctacagg
     6661 tccggaaacg atggtagtac aacagggtaa taaggtaacc ggcctggtag aggaccagat
     6721 gggacctgtc gccggagctt ctgttgtagt gaaaggaacc actatcggta cgataaccga
     6781 tatcgatgga aagtttacgc tggataatgt tcggcgggga gcggttattg ttatttcctt
     6841 tgtcggcctg gccactcagg agatcacttg gaacggacaa tctattttaa atgtaaaatt
     6901 aagtgatgcg acacaggacc tggatgaagt cgttgtcgta gcctatggaa cggctaagaa
     6961 atcaaccttc accggatcgg cctccgttgt aaaagctgaa aaactcgaaa agatcatggg
     7021 ctccggcttt gcggaagcat tgcaggggat gagtgccggt gtgaatgttg tgaatgtaca
     7081 gggtaacccc ggagctgatg cccgtgtgga gatccgtggt attgcttcca tgtccggaaa
     7141 ggccgatccg ttatatattg tggacgggat gccttacgat ggaaaactga atcagatcaa
     7201 tcctacggac atagaatcga tgacggtgct gaaggatgcg gcggccactt cgctctacgg
     7261 ttcgcgtgca gcaaacggcg tcgtaatgat tacaaccaag cggggtaaat cagaaaaacc
     7321 gcgtattaac ttccgcggag gttggggtac ttcggataat gctgtcaaga atccgaaaaa
     7381 agccgatccg taccagcagc tggaaaatac ctggtatgcc ttgtattatg atgcccttct
     7441 ttatgacggc atgaatatgc aacaggcggg cgattatgct tcgtcgcagg cattgaccaa
     7501 acaggtaaag gctacaaaag attcgaatgg taatctgatt tatgtcactc cgttcagaca
     7561 tatcaatgaa aattacgtat tgcatgacgg caatgggaat ccttacatga atcctaatct
     7621 ggaatatgtc tgggatgaag atgattggga tgtctacaaa gctatcttct cccgtaaact
     7681 gcgccaggat tatagtgtgg atataagtgg tcaggccaat ggtggaaaaa cagcctattt
     7741 cttctccggc ggttatctgg acgaccaggg atatggtaac cggcagtatt ataaacgtta
     7801 ttctttccgt accaacctga gtacagagtt gttcgattgg tggaaagtgg ccggtagcct
     7861 ttcttattcg cgtcatcgcc agaacctttc cggtggtgcc agccgtgcgg ctaactttac
     7921 gacgactttg tcttcaccct ggttacgtaa tgaagataat accggttggg tcgtttctga
     7981 aaaaacaggg gaacggatgt acagttacgg taaatatacc aataacttct ttggtgccca
     8041 tatcctgaat aactcgggtg attattggga taatccgaac gatgacagtt tcgataacaa
     8101 tatggggcat atcctgtctg ctcaggtaaa tacagagttt actcttcctt tcaacctgaa
     8161 attccgttcg gctttgaata ttgacgatta ctggtatcgt accatgcaat atacttccgc
     8221 cgtacatggc agcggacaga ctgcacctta tggtatttct atactggcag acggtggtta
     8281 tgccagccgt tataatttca ataaacgttc caccacctgg aataatgtat tgtctggtga
     8341 atggatgatt ggtgaccata cgatttcagg tctggtcgga catgagtggt atacctggga
     8401 ctcccactac gaacaaggtt ggggtgaagg tatcatggaa ctgggtaaat atgaattatc
     8461 gaataccacc aagaacttcg gtgtttccgg cggacgtgat aaatactctc tgctttcgtt
     8521 ctttggtaag gtcgattata acttcttgaa taagtattac ttgtccgctt cacttcgtga
     8581 ggatggttct tcccgtttca gctccgatca tcgctggggt acattctggt cgacaggcgg
     8641 ttcatggcga atatcgaaag aaggttttat ggaagacctg aaatggattg ataacctttc
     8701 gttgcgtggt agttacggta cgactggtaa tgataagctg atcgtgcgtg aatcgaatgg
     8761 taaggcaggg gatgaagtcc tttacggata ccagggtact tatgaaagtg atgacctgta
     8821 tctgaaatcc ggtttaaaac catctaccta tccgacaccg gacttgaagt gggaaagtaa
     8881 tcagcaatgg aatatcggtt tagatttttc cgtattcaac cgacttagcg gtacagtgga
     8941 atattattcc cgtacttccc atgacttgtt gtattataag gaactgcctc tctctgccca
     9001 ggttggtagt gcatccgggt ataatatgaa tatcggtgac ctgcgtaata gcgggattga
     9061 aatcacattg aatgcgaata tccttacaac gaaagatttc agatgggata tcgatgccaa
     9121 catgagtacg ctgaaaaatg aggtgactta tttgcctaca ggtccttaca cttattctgg
     9181 taccgcctgt acctacaaga tggaggaagg caagtctctg tatgaattta tcgctcccca
     9241 gtacgacggt gttaatccgg aaaccggagt acccggctgg ttgatccgcg atggtaacgg
     9301 cggttggaaa cgtacggaaa agcaggaaga agtaacgaca gacgattttg tgtactgtgg
     9361 ctccgcgatt cccaaagtgt tcggtgctat caccaataac ttccagttca aagggatcga
     9421 cctgtcgttc atgttctatt attcttatgg ttccaaaata tcggactata catataaaga
     9481 acgtatcatg aaccgtccgg gtgtcggtgt gatacaggag ttggttgagg acagatggcg
     9541 tcagccgggc gatgcggatg tgcttatccc acgttggtcg tacaaccagt atggcgcgac
     9601 ggtaaaatat gcagataact tcgtattcga caaccactac tggcgtctga gaaacctgac
     9661 attaggctat acgctgccta agagccttac ccgcaaggcc ctggtaaacc tgcgtgttta
     9721 tgtaaccggt aataacctgt tgactttcgg tcctgccaaa aaacgctaca cagaccccga
     9781 aacaggtata atgggtaaca gttataacgg taatgctgaa accgataacg gtattcaggg
     9841 ttcgagaaga ctgtatatgg tcggtattca aatcacattg taaacgtaaa aaatgatatt
     9901 tatgaaacga tttataaata tatccttcct gtccctggtt tttgctggta tggccctgac
     9961 cggatgtaac gacgacctga caaccagctc ctacgtgaaa gtaaacgatg aagatgtact
    10021 ggggaatgtc tcccagttgg aaaaagtatt gacttcagcc tataagcagc tgtattttaa
    10081 tactgataaa ggggaccgtg tgtatgccgg tcttcccgga ttccagatgt atgtcgatgc
    10141 gagtggtgcc gacgtgatca gccataccaa tatgggaggt gatcaggtaa cagcatacca
    10201 gtattccaac tcaaaaacac aggctgacgg aaatgcctca aaaatctggt cgatgtgcta
    10261 taatgtgatc aaccgtgcca atatcatcct gaccaatgtg gatgccgccg ccggtgatga
    10321 aacacagaaa aaacatatca aaggccaggc gttggcgatg cgtggaatcc agtatttcca
    10381 tctgatccag aattaccagc agacgtatgc gatagctaaa agcaagcgtg gggtgatcct
    10441 gcgtacctct tccgat
//
