LOCUS       c00021_gnlPro..        13344 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJOBFCEN_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:18:33
            Original ID  :: gnl|Prokka|EJOBFCEN_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13344
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13344
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[371:3344]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      372..3344
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13344
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13344
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             372..2600
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="Gly_radical (E-value: 3.4e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2616..3344
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="Radical_SAM (E-value: 3e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3372..3815)
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSRQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(3802..3993)
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             complement(3990..4493)
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             4687..4917
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MYYPDQPFLIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             5005..7122
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPTDEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(7378..7743)
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MTKIENQNQYEWAVKRVEDLLPLVKDDTPLNDPNSIELELLSNLV
                     ADYSEEHFSLGEPSLVDVLKLRMYEMGLNQKSLSQLIGVSPSRLSDYISGKCEPTLKVA
                     REISKKLNIDASIVLGV"
     CDS             complement(7748..8041)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MRIFTEQALREYAEEHPDSKVALQEWVTIVKKSEWACFADIKKTF
                     NSADSVGNQHYVFNVKGNNYRLVVVVKFTVKFVYIRFIGTHKEYDKIDCANI"
     CDS             complement(8140..8442)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(8408..8761)
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MEKKRKIRTYGGYFEAFMETLTEKEQDKIQYGLLLLKTQERLSTK
                     FVKFVQDGVFELRTEYNGNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGSEIDKALKIKE
                     EYYADKQSSNSRL"
     CDS             complement(8818..9063)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MSHLPPVIIEYRGNPKQYVSVVLDAINQGRLTYDGIANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(9072..9206)
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             complement(9333..10688)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 154.6; E-value: 1.1e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_14"
                     /sec_met_domain="MFS_1 (E-value: 1.4e-47, bitscore: 154.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGEALSSSDARRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFLADRSNINRFM
                     TTGLLITALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFGLMNVFALCLFLLV
                     PGAHFWIDVLAMVIFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEVD"
     CDS             complement(10702..11607)
                     /locus_tag="ctg21_15"
                     /transl_table=11
                     /translation="MLRKINILIALTLLIIGGLEAQNHSDKIIANLQKPASNSVLVVSH
                     RADWRNAPENSLQAIQNCIDMGVDVIEIDLKKTKDGHLILMHDKKIDRTTTGKGYPADY
                     TLEELRQFRLKSGTGHKTAHLIPTLEEVMSLCKGKILVNIDKGYDYFKDVYAVLKETGT
                     VQQCIIKAGLPYEQVKAENGDVLDKVIFMPIVQLHKDGAEAVIDSYQTHMKPAAYELVF
                     DSDSPEILNLIKKVRNTGSNLFINSLWPELCGGHDDDRAVELHQPDESWGWIIGQGAKL
                     IQTDRPALLLEYLREKKLHD"
ORIGIN
        1 aaaactgggt gtttgttttg caatctgctg attttcagcg tttgttgcgg agagacaggg
       61 attcgaaccc cgggtacctc gcagtacaac ggttttcaag accgccgcaa tcgaccactc
      121 tgccacctct ccaaaacttc cttttcagaa gtgcttttcg ttaaaagcga tgcaaaggta
      181 cgaacttttt ttaaacatgc aagagtttcc acgaaaaaaa tttcgggaag atttcctaag
      241 gatagcaata tctaggtatt ttatgttgaa aagcataaaa tagagcatat ttatgctgat
      301 tatatgaaaa aacgttgtaa ctttgtgcgc tctaaagaaa aggataacta caacctctaa
      361 ttttatcatt tatggaatta aataagatct ttaaagacgg tctttggagc acagaaatca
      421 acgtaagaga tttcgttagt cacaacatca ctccgtatta tggagatgct tctttcctcg
      481 aaggacctac cgaacgcaca aaagctgtat ggaaccgctg cctcgaagca ctggcagaag
      541 aaagagccaa taacggcgta cgctcactgg ataatgtcac cgtctcaacc atcacttctc
      601 ataaagccgg atatatcgac aaagaaaacg aactgatcgt cggtctgcag acagacgaac
      661 ttctgaaacg tgcaatcaaa cctttcggag gtatcaacgt agtgagcaaa gcctgccacg
      721 aaaacggcgt ggaagtggac gaccgcgtaa aagatatctt cactcactac cgcaagacgc
      781 acaacgacgg agtatttgac gtatataccg aagaaatccg ttcgttccgt tctctgggat
      841 tcctcaccgg acttcctgac aactatgccc gcggacgtat catcggcgac taccgccgta
      901 tggctctcta tggtatcgac cgactgattg aggcaaaaaa agaagatttg cgtaacctta
      961 ccggtccgat gaccgaagcc cgcatccgcc tgcgcgaaga agtggcagag caaatcaaag
     1021 cattaaaaga catgaaggta atgggcgaat actacggact cgacttgagc cgtcctgcct
     1081 acaccgcaca agaagcagta caatgggtat acatggctta ccttgctgcc gtaaaagaac
     1141 aagacggtgc tgctatgtca ctaggtaacg tctcttcgtt cctcgacatt tatatggaat
     1201 atgaattgag caaaggaacc atcacagaat ctttcgcaca ggagctgatc gaccagtttg
     1261 tcatcaaact gcgtatggtg cgccacctgc gtatgcaatc ttacaacgac atctttgccg
     1321 gcgacccgac atgggtaacc gaatctctgg gcggacgcct caacgacgga cgcacgaagg
     1381 taacaaagac ttctttccgc ttcctgcaaa cactctacaa ccttggccct tcaccagaac
     1441 cgaacttgac tgtattgtgg agtccggaac ttccggaagg attcaaagaa ttctgtgcaa
     1501 aagtatctat cgacacttct tccatccaat atgaaaacga cgacctgatg cgtgaagtac
     1561 gccagtctga cgactacgga atcgcgtgct gcgtatctta tcaggaaatc ggaaaacaaa
     1621 tccaattctt cggcgcacgt tgcaacctgg caaaagccct gttgcttgcc atcaacggcg
     1681 gacgttgcga aaacaccggt acggtaatgg tgaaaaatat ccccgtacta accagcgaca
     1741 cactgaactt cgaagaagta atgagcaact acaagaaggt actgacagaa atcgcccgtg
     1801 tttacaacga agcgatgaac atcatccatt atatgcatga taagtattac tacgaaaaag
     1861 cccaaatggc tcttgtagat accaacccac gcatcaacct tgcttatggt gtagccggac
     1921 tttctatcgc cctcgattca ctgtcggcca tcaaatatgc caaagtgacc gcacgccgca
     1981 acgacatagg tctgacagaa ggtttcgata ttcaaggcga attcccttgc ttcggtaatg
     2041 acaacgacaa ggtagaccac ctgggtgttg acctggtcta tttcttcagc gaagaattga
     2101 agaaacttcc ggtttacaaa aatgcccgtc ctactttatc tttgctcacc atcacttcca
     2161 acgtgatgta tggcaagaag acaggtgcta ctcccgacgg acgcgccaaa ggtgtcgctt
     2221 ttgctccggg agccaaccct atgcacggac gtgacaagaa cggtgccatc gcctctttga
     2281 gttccgtagc gaaattacgt taccgcgact cacaggacgg tatcagcaac actttctcca
     2341 tcgtccccaa atcactggga gctactgaag aggatcgcgt agaaaatctg gtgacaatga
     2401 tggatggcta tttcaccaaa ggcgctcacc acctgaacgt gaacgtactg aatcgtgaaa
     2461 tgctttacga tgccatggaa catccggaaa aatatccgca actcaccatc cgtgtttccg
     2521 gttatgccgt aaacttcgtg aagttgagcc gcgaacatca attggaagta atcagccgta
     2581 gcttccacga acgtatgtaa tcagatctac tcaatatgac gataaacgta cattcatacg
     2641 aaagtatggg aacattcgac gggccgggct tacggctcgt cgtttttctt caaggatgca
     2701 atttccgctg cctgtattgc gccaaccctg acacaatagc cgggaaagga ggcacaccta
     2761 ctccaccgga agaaatcgtc cgcatggcta tgagccaacg tccttttttc gggaaacgcg
     2821 gaggagtcac tttctccgga ggagaaccta cgtttcaggc caaagcacta gtccctttag
     2881 tgcgtgaact gaaagaaaag ggaatacatg tatgcataga cagcaacggc ggtatctgga
     2941 acgaagaagt agaagaactt ttcaaactga cggatcttgt attgctggat attaaagagt
     3001 tcaatccggc acgccatcaa gcactgaccg gaagaagtaa cgagcaaacc atccgcacgg
     3061 cagcatggct ggaagaaaac gagaaacctt tctggctgcg ttatgtatta gtgcccggat
     3121 acagcgattt cgaggaagac atccgccgtt taggagaagc tctgggaaaa tataagatgg
     3181 tgcaacgagt ggaaatcctg ccttatcata cattaggcgt acataagtat gaagcgatgg
     3241 agcaggaata caagctgaaa gacgtaaaag aaaatacccc cgaacaactt gaaaaagccg
     3301 cggaggtatt taaagagtat ttcactactg tggtggtcaa ttaaccacca cagtaataaa
     3361 taggataaaa atcaccatgt ctctgctttc acctcgaaac agggacactc tttgatccgc
     3421 tcccaagggt caacaattcc attataattg gtgtcaggac tcaagtcccg atgaccgacc
     3481 acctttgcat ccggataacg ctgcaacagt tcgcgcacca ggcgatgcaa agattctttc
     3541 tggcgggaag tacgcgtatc cgctgccttt ccgtcctcat ccagtccgcc ttcatagcac
     3601 acccctaaac taatcgcatt aaaaccgcgt gcatgagcac ccaccgtatc ttcatccctc
     3661 atcggctcta tctgtcccga cttgcgaatg tagtaatgat acccccaaca cgaaaagccc
     3721 cgaaagcgat gggcagtgtc cacatccttc gccgtgaagt cgcgatcagc acgggtagca
     3781 gagcagtgaa tcacaatcag actaatcttt ctcatcgtcc ttctcccttt ccgttgtttt
     3841 cacattacac acttccttat gggtagcatt gaagcgcacc tctctcacaa ttctgttccg
     3901 ctttcttttt ccgaagaaag gcacaaggaa catgattaca tccaaaatct tagttacaat
     3961 ttctttcatt tgatccaata ttaaagttat catgctgccg ggtccggagc ttctccgctt
     4021 ccaccaccgt ctgaaccacc accggaacct ttgtcatcgt cttctccttc attgccgcta
     4081 ccgcccgttt gagccaccgc acgcgtcgtt acctgctggt agctaagaat cttcgtgatg
     4141 tccgccaacg tctttccggg acgaaaaata atatgggcag ccgtaatcag cgaacttgaa
     4201 aactccttga ccgacacagc tccttcactg ttcaacccga tctgcaaact gcccaaatca
     4261 cccaaccgga ctattcttcc cgctttcaac gcacgcttcg cctcataaag aatacccgaa
     4321 atggcggcac gcacatctgt ctccgtacag gtagaccgac tggtgattcc ttcgcacaac
     4381 tcttcaaaat ccaactctcc cgaagcctgt gcctgcgcgt aatactttgc cgactcatcc
     4441 tttttggcag gattcttgcg cggcactact gaataagtta ctgtcattgc cataataaaa
     4501 taattttaag atttcacaca tttcgaacgc gttccttatt tgttaacgac ataaagataa
     4561 cacattttcc atcctccgga ttccccaacg aagtttcctg atactctatg aataataatg
     4621 acgttattct tttaataaac cattaatttt cagtaacttt atagcataaa ccaaacatca
     4681 ttcatcatgt attatccgga ccagccattt cttatccgca cttataaaaa gtcggaacta
     4741 gctcatcttt acaaccccaa cgtatgcctc aaagtagcct tacaaatact acgtcgttgg
     4801 attgtctaca accttccgct cctgcaagaa ctcgaacaag aaggctatcg tgcccgcaac
     4861 cgccttctct ctccccggca ggtggcaacg atcatacgct atttgggaga accctaagaa
     4921 cttaatcaaa aaaacgaaaa gttccattct attattttac aaacaaattt ctttgcaacc
     4981 gcaaattaaa aagaacaaac caacatggat cattttacca tctttcaaga cttttaccgc
     5041 gtcatagccg aaatgacaga agaagaaatc gtatcggcca tcagcaacgg cacataccgg
     5101 gaaacagtgg aggacgtgcg ccgaatcttc gcggaacaag gcgagaaagc agccaacgaa
     5161 aagaaaatag aactaccgga aatcaccttt tcagccaact accggggagg acgttcaaac
     5221 gcaactctcg tcaagtatct gggatacatc gtggtagaca tcgaccatca gacacaggaa
     5281 gcattggcac gcatcctcgc actggcaaaa aagtgtgccc acacccgcat cgctttcatc
     5341 agccccaaag gaatgggact gaaaatcgtg gtacgtgtat gccggacaga cgggacattg
     5401 cccgaaacaa ttcaggaaat tgaagatttc catcatgctg cttatcacaa aatcgcttcc
     5461 ttttatgccc agctctgcgg agttgaggtc gacacttccg ggcaggatgt tagccgcact
     5521 tgcctgttct cttacgatcc ggatatttat ttcaatcccg atgccacagc tgtcatcgtg
     5581 gaacagccac cgatgttctt caagtctcaa aagaagaaaa gggcatccgg caaaaagaaa
     5641 aagacgacag caccagacaa caatcccctc accgaacaag tggccctcaa ctaccattcc
     5701 tcgcacgctt ccttaatggt gactctgaac tattatcaca ataaatccga aaagtacgtc
     5761 accggcaacc ggaacaacta cctgcattgc ctggcttgta tgtacaatcg ctacggcgtc
     5821 ccccaggaag aggcggcagc ttttatcaag agccagttca ccgatcttcc cacggatgaa
     5881 atggacgcac taatcgggag tgcttacgga cacaacgagg aattcgacac ccgcaagctg
     5941 aatagtacgc agaagcgaat gttacagatt gagcaacata tcaaagaaaa ttacgataca
     6001 cgctacaacg aagtgcttca tatcatggaa tatcgcagaa ggaaaacgga cacggagcaa
     6061 ccggaacctt tccatattct cgacgaaatg atggaaaaca gcatttggat ggagatgaac
     6121 gaactgggct attcgtgcac cgtcaagacg attcagaatc tgatctactc cgacttcagc
     6181 atcacctacc atcctattcg cgagtattta gactcgctgc ctgaatggga cggaacggat
     6241 tatatcggta tccttgccaa cagcgtgcat actagtcacc agaaattttg ggtagaatgt
     6301 ctggaacgtt atctggtggg aatgtgcgct gccgccacac aagatgatgt ggtgaaccac
     6361 actgttttgt tgctttgcag cgaaatacag aacatcggaa agactacgtt tatcaacaac
     6421 ctgctgccgc ccgaattgcg cgcctatctt tctaccggtc ttatcaaccc gagcaacaag
     6481 gatgatctgg ctaaaatagc gcaggcgatg cttatcaatc tggatgagtt tgaagggatg
     6541 agcggacggg aactgaatat cttcaaggat ttagtcaccc gcaaagtaat cagcatccgc
     6601 ctgccatacg cgcggcgttc gcagaacttt cctcatacgg cttcttttgc cggcacatgc
     6661 aattaccagg aagtgcttca cgacaccaca ggtaaccgcc gttttctctg ctttcatgtc
     6721 gactcgatgg agtttattaa aataaactac gcgcagttgt atgcacaaat caagtatcta
     6781 ctcaacaagc cggggtatca gtattggttc acccagtcgg aaaactcacg gattgaagag
     6841 aacaacgagg atttcatttt ccactcaccg gaagaagaac tggtgttgac acatatccgc
     6901 aaaccggaac gtttcgaaaa ggtgcattat ctgacggtca ctgaaattgc ggaattgatt
     6961 cgcgaacgga cggggtatca atattctcac ggaaccaaag cccaactggg aaaagtgatg
     7021 tccaaacacg gcttcgaatt tcataaggga aaaaacggga gaagatacac tgtattcatt
     7081 attgatacgg aacaggtgaa atcaaacagg ctatatgaat aagatttcat ctccttcgca
     7141 cgcaaaaagg tgagggttgg tgagggtact tttgcaactt ttcattttta tatttcttat
     7201 ttctattctt ctattttctt ctaaaaaaaa aaatacgaat gttagaaatt taccctcacc
     7261 taccctcacc tttttccttt ttcttcctct ttcttcctca aaaaaacggt gggaaatttg
     7321 aaaaagacag ttatcttttt caaatttccc accatgtttt tttaatctga atcgaagtta
     7381 tactcctagc acaatactag catcaatatt cagcttttta cttatttcac gagccacttt
     7441 caatgtcggc tcacattttc cggaaatgta gtcactaaga cgcgaaggac taactcctat
     7501 cagttgtgac agtgatttct gattgagccc catttcgtac atacgaagct tcagaacatc
     7561 cacaagcgaa ggttctccca aagaaaagtg ttcctctgaa taatcggcaa caagattaga
     7621 aagaagttcc aactcgatgc tgttaggatc attcaaagga gtatcatcct tcactaacgg
     7681 aagaagatcc tccactctct ttacagccca ttcatactgg ttttggtttt ctatctttgt
     7741 catattttca aatattagca caatctattt tatcatattc tttatgagta ccaataaagc
     7801 gaatatatac aaactttaca gtgaacttca ccactactac caagcgataa ttattccctt
     7861 taacattgaa aacataatgc tggttaccta cactgtcggc actattaaag gtcttcttta
     7921 tatcagcgaa acaagcccat tcacttttct ttactatagt aacccattct tgcaaagcaa
     7981 cttttgaatc gggatgctcc tctgcatatt ctcttaacgc ttgttctgta aatattctca
     8041 ttagttactc acttatcatg caacaaaaat aagaatataa ttccaatttt caaaattata
     8101 ttccgatatt cgcaattatg gataaaaaag attcgcttct tataaagaca tcgaaaattc
     8161 gatcctacaa cctaacgcat tcatgatgcg atagaaagta gaaaccttag gttctgtctg
     8221 accactttcc actcttgaaa tataagaacg atcggaaccg atacgccggg ctaattctgc
     8281 ttgagtaatc ttagcctttt tccttgcgtc ttcgataatt tgcccggtgt agaaagcata
     8341 cgctttttct tctgcttccg cacgttcggg agtaccttct gctccaaatt tcgcatcaag
     8401 aacagcgtca taatctacta tttgatgatt gtttatctgc ataatattcc tcctttattt
     8461 ttaatgcttt atctatttca ctacccggtg ttttttgcga cttcttttga aagccattaa
     8521 acaacactac aatatttcca tcatcaaaaa tgaaaaatac ccggtatata ttaccattat
     8581 attctgtacg aagttcaaaa actccgtcct gaacaaattt tacaaattta gtggagagtc
     8641 tttcttgtgt tttcaacaag agtagtccat actggatttt atcttgttcc ttttcggtta
     8701 aagtctccat gaaagcctca aagtaacctc cgtatgtacg gatcttacgt ttcttttcca
     8761 tactgcaaat atacgaattg ttgttcaact atacaacaat cgtcttttta ttttatatta
     8821 tttttcctca aattctccag cacgcttttt cttctcataa gacaccagcg tctctacact
     8881 aagcgttttc ccattcttag ggcttatcac atctacaacg cttgctaacg cacgaaaagt
     8941 ctgttcgcaa tttgctattc cgtcatacgt caacctaccc tgattgatgg catcgagcac
     9001 aacagagaca tattgcttcg gatttccccg atactcgatg atgacaggcg ggagatgcga
     9061 catctctcga gtcagttgac cgacgattct tttttttggt cgagcagatc cattaatttt
     9121 tcactatgca cattgatttg tgcggttact tcacgaagtt catctttcaa tgaacacaat
     9181 aattcatcat tcaatgaatt ttccataaaa ctttctattt aattgattat aaaaaagcca
     9241 ttccagaaag ataagcaatc attacttact tcccggaatg gtgtctaata cctcgaaaac
     9301 aaagacttat attctaacct aatgtactca ctttaatcca cttcttttga ttttgcattc
     9361 cataccagca aagcaaacaa caccgaaagc aaagcagcac caatccaaaa ccaattgata
     9421 taagtaaagt cataaacatc aacgccattc tgaaccgttt tttgcccttc tatcagaata
     9481 ccgctcatca cgtcctgcaa tccggcaccg atataactgg caataccgac tactcccaat
     9541 gcagcacccg aagcattacg gggagcaata tccactgcca tcaaaccacc cagaaaacag
     9601 atcaaaactc cgatacctaa accgaaaata accattgcca acacgtctat ccaaaaatga
     9661 gctcccggaa ctaagagaaa caaacaaaga gcaaacacat tcatcaatcc gaaaattaac
     9721 gcaggaacat tgcgacgtcc accaaataac ttatcagaaa taacacctga aaacatagta
     9781 ccgattatac cacagaccgg acaaatagaa atgataaaac tggcatccaa ggtggagtaa
     9841 cccttttgag cttccaaata aaaaacgccc caactattga tagcataacg actgatatac
     9901 ataaaagcac tcgaaagagc cagtatccaa atggcaggca tcagcaatac ctgacgctgt
     9961 gctttattaa aatcagccgt ttctgtctca ctcatttcct ttttctgttt gggaacattc
    10021 accgaaggga accccatgct ttcgggagta tcatggaaga acttccagac gatcaacgct
    10081 cctatcaatc ccactatacc ggctccgaag aaaccatacc gccagcccaa cacactgaca
    10141 attgaggcta ttatcagaaa agtcaacgct tcgccgatat tatggctcgc agaccaaaag
    10201 ccatagtatg aaccgcgttc tttgtccgtg aaccaacggg aaagccctac tacacaggat
    10261 gctgccccca tagattgaaa ccagccgcta atcccccaaa ggatagcgaa caggataaaa
    10321 gaattagtaa aaccgagaca aagattaacc aaagcagtta tcaataaacc ggtagtcata
    10381 aaacggttga tattgctgcg gtcggcaagg aaaccgttcg tgaatttccc gatcgcatag
    10441 gtgaaaaaca atacggaacc tatgatgcct aactctgttt ccgaaaaaat gccttcatct
    10501 acaataggtt tctttacgac attcagacta agacggcaca cataatacat accataaccg
    10561 aaagtagctg aaaggaaagt agaccatttc agaaacttca gacggcgagc atcggatgaa
    10621 gacaaagctt ctccgttaca aggtctcggc gaagagacct tgtaaaaatt gattagttgt
    10681 ttcaacatga agaaagtgcg tttagtcgtg aagtttcttt tcgcgtagat actctaataa
    10741 tagagctggg cggtctgttt gaattagctt ggctccctgg ccaattatcc acccccaact
    10801 ttcatccggc tgatgaagtt ctactgcacg gtcgtcgtca tgcccgccac atagttcggg
    10861 ccaaagcgaa tttataaaaa gattagagcc tgtattacgt actttcttta tcaaattaag
    10921 aatctccgga ctgtcactat caaacactaa ttcataagca gcaggtttca tatgtgtctg
    10981 ataactatca atgacagctt ccgccccgtc tttatgaagt tgtacaatag gcatgaagat
    11041 taccttatcc aatacatcac cgttttcagc cttgacttgt tcataaggaa gtccggcttt
    11101 aataatacat tgctgaacag ttcctgtttc tttcaaaaca gcatatacat ctttgaagta
    11161 atcatagcct ttatcaatat taacaaggat cttaccttta cataatgaca ttacttcttc
    11221 caatgtcggt atcaaatgag ctgttttatg ccctgtacca cttttcaaac ggaactgacg
    11281 taattcttcc aatgtatagt ctgccggata accttttcct gttgtagtac gatcaatttt
    11341 cttgtcatgc atcaaaatca gatgtccatc cttggttttc ttcagatcga tttcaattac
    11401 atctaccccc atatcaatac aattctggat agcctgcagg gagttctccg gagcattacg
    11461 ccagtcagct cgatgagaaa caactaaaac tgaattactt gcaggcttct gtagattcgc
    11521 aattatttta tccgaatgat tctgtgcctc taaccctcct attatcagaa gggttaaagc
    11581 tattaatata tttatctttc taagcatatc tttttatttt tgtaaagcat ttctttttgc
    11641 attctgtccg cgctgtgccc atggtgaatt tgcaggccct tcaataccac aatcaatagc
    11701 tatcaatttg caggcaccat tatcctcata cgtgacatac acaataccat agtcagcaat
    11761 gactggtgac gaccaaattt tagaacctaa ttgtctctta tatttctccg taccatcagc
    11821 attcaatatt atatagttac cgccatcatc acagatgtga atatttccgt cactgtctat
    11881 agccggtgtt gttcctattt cagcgacaga ggaataactc catttttttg ctcctccttt
    11941 agtcagggca acaacttggg cattcggatt ctttgtaccc acatagatgg ttccgtcagc
    12001 accgatagcc ggtcctccct ggtcaatctt gcccatagta ccactcgccg gatatctcca
    12061 tagctcatta ccctggttat cataagcagc aaccactccc tctgaaaatg ccacatatac
    12121 atttccttgc gcatcaatag caggatatac agcagcagcc gtatttcctt tccctagatt
    12181 aggagacaag ttcacaccat cttgcgtagt acgggcaaat ccgttcgctc ccgacaaggc
    12241 tgaatagata actccattct gtccaaccga tataccacca ttagcaccac cattgggaga
    12301 tttgcgtctc caaagttgtc tgccggaact acggtcaacc atatgtacag aaccatccgt
    12361 ccctctattt ccaatcaaga tattaccatc acgagacaaa gcaggagaaa tatagggaat
    12421 attagtacca atacctagtt cgtatctcca cttctgtgtc ccatccggat gaatagcata
    12481 cagactgctg cttatgtttt tgtctgttgt actcgcaccc atataaatag ttccgtccgc
    12541 acctaccata ggagacgaac cttgatctcc agctcctccg tccttactta aatcaaacat
    12601 ccatttttgc tctccagacg gcgaataagc aaaaaggtgg agtgcattgg atgacacata
    12661 tacatccccg ttgtcaccta cagcagggga tatggatcgt aaagaagaag atgtctcaaa
    12721 cgtcttgtcc caaagaatcg tcactccgga tatggaggtg tcacgaacgt acagagtagc
    12781 ttgttttgta ttagtagctc cacgatcatc agtagttgtc agctttactg ttacaaatcc
    12841 agttgtcgtg aaagttattt ccgggtcttt ttcttgagag gtctgtccat tgccaaagtc
    12901 ccactcgtaa gcaactactt ctccatcctc atccacagac ttatcggtaa attgaacttt
    12961 ctcattcact ttacaaatgg cagggctata gctgaagtct gtaaccggag gcatattcgt
    13021 cggacgaatc acaacagtat gggatgcagt tgcatatcct ccgaattcat ctgtcacggt
    13081 taatttaata acataggttc cagctttctt atacaaaacg gacgcatctt tagtagtagc
    13141 cctattccct tccccctcaa atccaaaatg ccagaagtac tctactatct ctccttccgt
    13201 ctttactgat tcatcagtca gataaacgat atcaccgacc gtatattctt ctttatctat
    13261 agaaaaagaa gcctccgggg aggttgtctg ccgcacttca tcgccgtcct tacatgcaaa
    13321 tagacaaacg actgtcacta tcag
//
