LOCUS       c00117_gnlPro..        11749 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DDGAJHJB_117.
ACCESSION   c00117_gnlPro..
VERSION     c00117_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:29:36
            Original ID  :: gnl|Prokka|DDGAJHJB_117
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11749
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11749
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4325:9185]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4326..9185
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..11749
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11749
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..79
                     /locus_tag="ctg117_1"
                     /transl_table=11
                     /translation="GVNNVYEATKYTLRAGLIEMVEYYI"
     CDS             152..1081
                     /locus_tag="ctg117_2"
                     /transl_table=11
                     /translation="MAKKGELHIRNKHNGQYDFPLLMENYPPLKRFVSLNPLGIQTINF
                     FNPQAVKALNKALLVTYYGIRYWDIPKQYLCPPIPGRADYIHYIADLIQPNGTTPDLPA
                     GDANGQKSKCRCLDIGVGANCIYPIIGHTEYGWTFVGTDIDPVSIENARKIVTCNPVLA
                     HKIDLRLQKDSKKIFDGIIMPDEYFDVTICNPPFHSSREEAEDGTLRKLSSLKGTKINK
                     VQLNFGGSANELWCEGGEVRFLLNMISESQKYQKNCGWFTSLVSKEKNLEKLYTKLKSV
                     NVSEYKVIRMQQGTKSSRILAWRFATNS"
     CDS             1137..1916
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_3"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.5e-08,
                     bitscore: 23.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNYITLTKENIANEHICCAFSDKKCKDSYELKKEWLKKEFDNG
                     YVFRRIDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAIDD
                     AKLQGKDGLVTVVGTSKFHFMSDTKWLLRQGFQTIEKLPYGFSLLSLKLNPAAPDPSFN
                     DCVLSGECPDKDGIVVYYTHRCPFTEFHVRGSLVSAAKSKDIPLRIIELESMEQAQNAP
                     TPATIFTLFYNGKFVTTDLSVCLEGRLSKALGCDSGE"
     CDS             2058..3815
                     /locus_tag="ctg117_4"
                     /transl_table=11
                     /translation="MRFWVCIFVLLFVHNQFSRADKIINNDSLYTEKYIRDIYISNPKR
                     ALQLLDEAETRKAFPLRLINELRSLSYRNMYMNKLAFMYARKSYLLDSISQREPKHMLK
                     MTVYLAELSSIMSKYNESMHYALSGIMQAQKLKDREAEARLLFCIGENNWRLSLKDEAY
                     NYFGRTIELLRGSKDMREMMLLSYYYGAEMGFLMTDSRIDEALALAYEREKLLKKLEKV
                     PEVPEGYIDGQYSYLYAKLAYISYLEKKYAQAEGYYQKYLAIKESHTPDGKMYSIPYLI
                     LSKQYETVIDNCKDFKELLRTQRDTLNAQYLTILNKEVQAYLGLNRYKEAAEIRETIIA
                     ITDSINSTDRKNAALELNAMYGASEKEEYIAEQASQLKIRNVSLCFLACIVVLTLFILW
                     RLWRFNHIIEYKNRMLAKLINEKFANKKDGNQLLEVYEEQEVSSELEPELISPEEQDEL
                     LDETDKESGEEEENKKIFQELNHTVVQKQLYLSPELSREDLAQIVHLNNARFARMIREC
                     TGTNFNGYINGLRINYAIKLMKKYPNYTIRAIADESGFNSAPILYNLFKKKTGMTPYEF
                     KKAQDTLRN"
     CDS             3880..4242
                     /locus_tag="ctg117_5"
                     /transl_table=11
                     /translation="MIQVRIKRVYEDFSETDGYRVLVDKLWPRGMKKEWLKYDYWAKDI
                     TPSPTLRKWFHEDIPGHWGDFVTQYQKELDASPSMADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMRLRE"
     CDS             4326..5558
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_6"
                     /sec_met_domain="HBT (E-value: 1.7e-18, bitscore: 56.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNG
                     FALFTYHDDTIITDSPENEHIQNEARLNDLQIIKEEEFSAAVDFAPCKCMLVSDDEEAL
                     LGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLGMKREEVIAVGDGV
                     CDVTMIQLAGLGIAMGHSQDSVKACADYVTASNEEDGVAVAVEKAIISEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             5555..6670
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_7"
                     /sec_met_domain="Chorismate_bind (E-value: 2.3e-57,
                     bitscore: 184.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVRL
                     IYDLKELNGQRGFVIAPFQVSETCPVVLIQPDQWGQPLPIDNDTAEEREVALRMQGQES
                     FLTSSTEEYASCFHTFINALRDNTFDKLVLSRHLTIDKVSGFSPLSIFRAACRRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWHTVALAGTQPLQDGRLPQVWDEKNRKEQDYV
                     ASYIRRQLLSLGIHSTENGPYPAYAGALSHLKTDFRFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYRFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMHIEDEQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIATPPLKS"
     CDS             6690..8357
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.5e-08, bitscore:
                     21.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYAVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVVISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINVPISEPLFQFTVDALPEVRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMN
                     LIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKIDQMVPELLIT
                     YGGHVVSKRLKKFLRQHPPKEHWHVSPEGEVVDLYGSLTTVIEMDPFEFLEKIASLLDN
                     RTPDYPRVWENYCKIIPEPDFAYSEMLAVGTLLKALPESCALHLANSSVVRYAQLYSIP
                     SAIEVCCNRGTSGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNINVRSNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQAQNDEELTEAM
                     KTFTQPETMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             8361..9185
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_9"
                     /sec_met_domain="ECH_1 (E-value: 1e-82, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             9246..10271
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_10"
                     /sec_met_domain="MR_MLE_C (E-value: 4.4e-30, bitscore:
                     94.4, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRLLHFKQPAGTSRGTYTTRKVWYLHFTSPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILIRTCRQVEEEQGKLDKDGLCKYPSILFGLETAIWHFF
                     AGSWALSDTAFSRGEVGIPINGLIWMGDFENMLSQIEKKMEAGFRCVKLKIGAIDFEKE
                     LALLRHIRTHFSSKEIELRVDANGAFSPGDAMEKLKRLSEFDLHSIEQPIRAGQWEEMA
                     RLTSESPLPVALDEELIGCNTLEEKKKLLATIRPQYIIIKPSLHGGICGGDEWIMEAEK
                     QHIGWWITSALESNIGLNAIAHWCATFNNPLPQGLGTGMLFTDNIEVPLEIRKDCLWFC
                     K"
     CDS             10303..11436
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 54.6; E-value:
                     2.4e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_11"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-18, bitscore:
                     54.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQQQRLLLEGKEYTFEEISQLIAGGAEAHSPAYWDLYLFLN
                     EWFNDSPVITVHTSGSTGIPKELMVRKDQMMQSARLTCEFLNLKKGESALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKEPLRFVAMVPLQVYNTMQVPEEKERLKQTD
                     ILIIGGGAVDEALETEINHLPTAVYSTYGMTETLSHIALRRLNGASASEHYYPFPSVKL
                     SLSAENTLIIDAPLVCDETLQTNDIARIYPDGSFMILGRKDNVINSGGIKIQAEEMEKL
                     LRPFIPVSFVITSVPDQRLGQAVTLLLADQPDTEEIGNKLHEILEPYYRPKHILTIESI
                     PQTENGKINRAECRILAKQMLMTFYPHTLTLSRPAPN"
ORIGIN
        1 gggtgtgaat aatgtatatg aagcaactaa gtatacttta cgcgccgggc tgattgaaat
       61 ggtagaatat tatatatgat attcagaaga gtgttaggat aagagttaag aagaatttgt
      121 aggcaggaaa attctctgta tctttgcccg catggcaaaa aaaggtgagt tacatataag
      181 aaataagcac aatggtcagt atgattttcc attgttgatg gaaaattatc ctccattaaa
      241 gagattcgta tcgctcaatc ccctcggaat acaaactata aactttttta atccgcaagc
      301 ggtgaaggct ttgaacaaag cattattggt aacttattat ggcatccggt attgggacat
      361 accgaagcaa tatttgtgtc cgcctattcc cggaagggcg gattacattc attatattgc
      421 cgatcttatc cagccgaacg gaacaacacc ggatttaccg gcaggagatg ctaatggaca
      481 gaagtcaaaa tgtagatgtc tggatattgg ggtaggtgca aattgcattt atccgatcat
      541 aggacacact gaatatggat ggaccttcgt tggtactgat attgatccgg tttcgataga
      601 aaatgcacga aagatagtga cttgcaaccc tgtgttggct cataagattg acttgcgact
      661 tcagaaagat agtaagaaga ttttcgatgg aattattatg cctgatgagt attttgatgt
      721 gacaatatgc aatcctccgt ttcatagttc gcgtgaagag gcggaagacg gaacgttacg
      781 caaattaagc agtctgaaag gtacgaagat aaataaagtg cagctaaatt tcggcgggag
      841 tgcgaatgaa ctttggtgcg agggcggaga agttcgtttc ttattgaata tgatttccga
      901 gagccaaaaa tatcagaaga actgcggatg gtttacgagt ttggtttcta aagaaaaaaa
      961 tctggaaaag ttatatacca aattaaaatc ggtgaatgtg tccgaatata aagttattcg
     1021 aatgcagcag ggaactaaaa gtagcaggat attagcttgg cgatttgcta ccaactcata
     1081 acaatgagtg aatatcgaac tgttatttgt ttaacctatt aattaaatag aatattatgg
     1141 aaaccaatta catcactttg acaaaggaga atattgcaaa cgaacatata tgctgtgctt
     1201 tttcagataa gaaatgcaag gatagttatg aactcaaaaa agaatggctg aagaaagagt
     1261 tcgataacgg ctatgtgttc agacgtattg atgaacgggc aaaagtgttt atcgaatacg
     1321 gtcctgctga aaaagcatgg gttccggtga atgctcccaa ttatctgatg ataaactgtt
     1381 tctgggtgtc aggtaaatat aaaggttgcg gacatggtaa ggcattattg cagtctgcca
     1441 ttgatgatgc aaaattgcag gggaaagatg ggcttgtcac agtggtgggc acttctaaat
     1501 ttcattttat gagtgacacg aaatggctgt tgcgacaagg tttccaaaca atagaaaaac
     1561 tcccttacgg attcagcctt ttaagtttga aactaaaccc ggctgctcct gatccttctt
     1621 ttaatgattg cgtgttgagc ggtgagtgtc cggataagga tggaatagtc gtttattata
     1681 cccatcgctg cccgtttacg gagtttcacg ttcgcggttc tttggtcagt gctgctaaga
     1741 gcaaagacat tccattgaga ataattgaat tggaaagtat ggaacaggcg caaaatgcac
     1801 ctactccggc taccatattt actctttttt ataatggcaa gtttgtaacg actgacttaa
     1861 gtgtatgcct tgaagggcga ttgagcaaag cattgggctg tgattcagga gaatagctga
     1921 cttggaacca tgttacgtct ctgatatgtt tagctaatgt ttcttatttt tattttgcaa
     1981 atttaaattg tgtctgcaca ttttttggaa aatacatacc tttggataat taatgattaa
     2041 acacgattaa gagttttatg cgtttttggg tatgtatttt tgtgcttcta tttgtacaca
     2101 atcaattttc aagggctgat aaaattataa ataatgactc tttgtataca gaaaaatata
     2161 tcagagatat ttatatttcc aaccccaaac gtgctttaca gttgttggat gaggccgaaa
     2221 ccagaaaagc cttccctctg cgtctgatta atgaattgcg cagtttgtca tatcgtaata
     2281 tgtatatgaa taaactagct tttatgtatg caaggaagtc gtacttgctt gattccatct
     2341 ctcaaagaga acctaagcac atgttgaaga tgacggttta tttagctgaa ctttcatcca
     2401 taatgagtaa atataatgag agcatgcatt atgctcttag tggaattatg caggctcaaa
     2461 aactgaagga cagagaggcg gaagctagat tgcttttttg cataggagag aataattgga
     2521 ggctgtcatt gaaagatgag gcgtataatt attttggtcg tacgattgaa ttactgcgtg
     2581 ggtcaaagga tatgagagaa atgatgctgc tttcctatta ttatggagca gagatgggat
     2641 ttttaatgac agattcccgt attgatgaag ctttggctct tgcttatgaa cgtgaaaaac
     2701 ttcttaaaaa attagagaaa gtaccggagg ttcccgaagg ctacattgat ggtcaatata
     2761 gctatttata tgcaaaattg gcctatattt cttatttaga aaagaaatat gcgcaagcag
     2821 aaggatatta tcaaaaatat ctggcaataa aagaatctca tactccggat ggcaagatgt
     2881 attcgattcc ttatttgatt ctttccaaac aatatgagac agtaatagac aactgtaagg
     2941 actttaaaga attgttgaga acacagcggg ataccttgaa cgctcaatat ttaactatac
     3001 ttaataagga agtccaggca tatctggggc tgaatcgtta taaagaagcc gcagaaatac
     3061 gtgaaaccat cattgcaata acggatagca ttaacagtac cgacaggaaa aatgctgcat
     3121 tagaattgaa cgcgatgtac ggtgcttccg aaaaagaaga atacatcgcc gagcaagcct
     3181 cacagctaaa aataaggaat gtttcactct gctttttggc gtgtattgta gtgctgaccc
     3241 tgtttatact ttggcgtttg tggcgtttca accatataat cgagtataaa aacaggatgc
     3301 ttgccaaact gataaacgag aaatttgcca ataaaaaaga tggtaatcag ttattggaag
     3361 tgtacgagga acaggaggtt tcatcagaat tggaaccgga attgatttct cctgaagaac
     3421 aggatgaact tttggacgaa acagacaaag aaagtgggga agaagaggag aacaagaaaa
     3481 tattccagga attaaatcat acagtcgttc aaaaacagct atatctttct ccagagctct
     3541 caagagaaga tttggcgcag attgtacatc tgaataatgc acgctttgcc cggatgataa
     3601 gagaatgcac cggaactaat ttcaatgggt acatcaacgg actgcgcatt aattatgcga
     3661 tcaagctaat gaaaaaatat cctaactata ccatacgtgc catcgctgat gaatccggat
     3721 ttaatagtgc cccgatatta tataaccttt ttaagaaaaa gacgggaatg actccttatg
     3781 aatttaaaaa agcgcaggac acattgagga attaaatagt tctactaaac aattttcgtt
     3841 tttcccggtt tatctattga taactaaata ttaatggaaa tgatacaggt aaggataaag
     3901 agggtttacg aagatttttc agaaacagat ggataccggg tgttggtaga taaattatgg
     3961 ccacgcggaa tgaagaaaga atggttgaaa tacgattatt gggcaaaaga cataacacca
     4021 tcccctacat tacgtaaatg gtttcatgaa gatattcccg gacattgggg agattttgtc
     4081 acgcagtatc aaaaagagct ggatgcttct ccatcaatgg ctgattttct gactcttatc
     4141 aaaccacatc cggtgataac actactttat gcttcaaaag aaccggtgta taatcacgcc
     4201 cgaattcttc gcgattatct ggaaatgcgt ttgagagagt gaaattaaag taattttatc
     4261 tgtttacgct ttctgtcgtt cactcaattt cctacctttg taatctaaat caaaatcgtg
     4321 taatcatgaa gtataaatta ttggttcttg atgtagacgg aacactcctc aatgatgcga
     4381 aagaaattag taaacgtaca ttggctgccc tgttgaaggt tcagcaaatg ggagtacgta
     4441 tcgtattggc atccggcaga ccgacttatg gcttaatgcc actagctaag atgctcgaac
     4501 ttggaaacta tggaggtttt atcctttcct ataatggctg tcagattatc aatgcacaaa
     4561 acggagaaat tctgtttgaa cgtcggatta atcccgaaat gttgccgtat ctggaaaaga
     4621 aagcccgtaa aaacggtttt gctttattca cttatcatga tgatacgatc ataacggatt
     4681 ctcctgaaaa tgaacatatc caaaatgaag cccggttgaa tgacctgcaa ataatcaaag
     4741 aagaagaatt ttctgctgcc gttgattttg ctccttgtaa gtgtatgctg gtgagcgatg
     4801 acgaagaagc attgcttggt ttggaagatc actggaagag acgactgaat ggggcgttgg
     4861 acgtattccg ttcggagccc tattttctgg aagtagttcc ctgcgccatc gacaaagcta
     4921 attctttggg tgctttgctg gaggtgctag gtatgaagcg tgaggaagtg attgctgtgg
     4981 gcgacggtgt gtgtgacgta acaatgattc aattggcggg gctgggtata gctatgggac
     5041 attcacaaga ctcggtgaaa gcctgtgccg attatgtgac tgcttcgaat gaggaagacg
     5101 gagtggccgt tgcagtggag aaggctatca tatccgaagt gcgtgcagcc gaaattcccc
     5161 ttgaccaact gaatgcgcag gcacgccacg cattgatggg aaacttggga attcaatata
     5221 cctatgccga cgaagaccgt gtggaagcaa caatgccggt agaccatcgt acccgtcagc
     5281 cttttggcat tttgcatggc ggggctactc ttgcattggc ggaaacagtt gccggactcg
     5341 gttcaatgat tctttgccag ccggacgaga ttgtagtagg aatgcaggtc agtggaaacc
     5401 acatatcttc tgcacatgaa ggagatacag tgcgtgcagt aggaacagtt gtacataagg
     5461 gacgttcctc ccatgtatgg aatgtagacg tgtttacttc aacaaacaaa ctagtgtctt
     5521 ccatacgggt agtcaacagt gtgatgaaaa agagatgacc gacgaagaaa taagtaattt
     5581 gacaactatt gatgcattta ttcagcggaa gcagccgttt gctgtttacc gtattcccgg
     5641 ggagaaagtt ccccgtctgt tgacacaggc ggaaggagcg gtacgtctga tatacgacct
     5701 gaaagaactg aatggacaga gaggatttgt catcgctccg tttcaggtga gtgagacgtg
     5761 tcctgtcgta ttgattcaac ccgatcagtg ggggcaacct ttgccgattg acaatgatac
     5821 ggcagaagaa cgggaagtcg ctttgcggat gcaaggacaa gaatcgttcc tgacttcttc
     5881 tacggaggaa tatgcctcct gctttcatac ctttataaat gctttgcgtg ataatacttt
     5941 tgataaatta gtactttcac gtcatcttac tattgataaa gtatccggtt tttctccttt
     6001 gtctatattt cgtgcagcgt gcaggcgtta tattcattca tatatatact tgtgctacac
     6061 tccgcagacg ggtatctggc tgggaagcac tcctgaaatc attttatcag gtgaaaaaga
     6121 cgaatggcat acggttgcgt tagccggaac gcagccttta caagatggca gactgccgca
     6181 agtgtgggat gaaaagaacc ggaaagagca ggattatgtc gcttcttata ttcgtcgcca
     6241 actcctatcg ttgggcattc attctacgga gaacgggcct tatccggctt atgcaggtgc
     6301 tttgtcacat ttgaaaacag atttccggtt ttctttgaaa gataacaaag gtttgggaga
     6361 tctcttgaaa gtgttgcatc caacgcctgc tgtatgcggt ttaccgaaag aagaagccta
     6421 tcggtttata ttgcagaacg aaggctacga ccgccgctat tattccggct ttatcggctg
     6481 gctggacccg gaagggcgaa ctgacatcta tgtgaatctg cgctgcatgc atattgaaga
     6541 tgaacaactg actctttatg ccggcggtgg actactggct tcttcggaat tgaatgacga
     6601 atggctggaa acggaaaaga agttgcaaac catcaaacgg cttattgcaa cgcctccttt
     6661 aaaatcataa actactaata attatcatca tgtatacaga caagaagaac atactccagt
     6721 tggttgcgtt gctcgaggcg cacgggatta ctaaggttgt gttgtgtccg ggtagtcgta
     6781 atacgcccat cgtacatact ttgtctaatc atccgaactt cacctgttat gcagtgacgg
     6841 atgaacggag tgccggttat tttgccattg gtcttgcgtt gaatggtggt aagcctgctg
     6901 ctgtgtgctg cacttccggt actgcattat taaatcttca tccggctgta gccgaagcat
     6961 tttatcagaa tgttccttta gttgtcattt cagcagaccg tcccgctgcc tggatcggac
     7021 agatggatgg acagacagtg ccgcaaccgg gtgtgtttca aacgctggta aagaagtcgg
     7081 tcaatcttcc ggagattcat acggaagaag atgaatggta ttgtaatcgc ctggtgaatg
     7141 aagccttgct ggagacgaat catcatggaa aaggcccggt gcatatcaat gttcctattt
     7201 ccgaaccgct gtttcaattc acggtagatg cactcccgga agtacgtgtg ataacccgtt
     7261 atcagggatt gaacgtctat gaccgtgatt ataatgatct ggtcgaccgg atgaataaat
     7321 atcagaagcg catgattatc atcggtcaga tgaaccttat ttatctgttt gaaaaaagat
     7381 atatcaagtt attatataaa cattttgcct ggttgacgga acatatcggc aatcagacag
     7441 ttcccggtat tccggtaaag aatttcgatg cggcacttta tgccatgccc gaagagaaga
     7501 tagaccagat ggttcccgaa ttgctgatta cttacggagg acatgtcgtt tccaaacgat
     7561 tgaagaagtt tctccgtcag catccgccta aagagcattg gcacgtatcg ccggagggtg
     7621 aggtggtcga tttgtacggc tcattgacta cagtgatcga gatggacccg tttgaatttc
     7681 tggagaagat cgccagcctg ctggataacc ggactcctga ctatccccgt gtatgggaga
     7741 attattgtaa gattattccc gaaccggatt ttgcctattc ggagatgttg gctgtcggta
     7801 cattattgaa agctttgccg gagtcctgtg cattgcatct ggcaaacagt tcggtagttc
     7861 gttatgcaca actatattcg attccttctg caattgaagt ttgctgcaat cggggaacaa
     7921 gtggtattga aggatcgttg tctaccgctg tcggttatgc ggcagcttcc gacaaactga
     7981 atttcatagc tatcggagat ctaagtttct tctatgatat gaatgcgtta tggaatatca
     8041 acgtccgttc caacctgcgt atccttttat taaataacgg aggaggagag attttccata
     8101 ctttaccggg attggatatg tcgggcacct cacataaatt tattgcagca gttcataaaa
     8161 cgtcagccaa aggctgggcg gaggaacgtg gtttccttta tctgcaggca caaaatgatg
     8221 aagagctgac tgaagcaatg aaaactttca cccagccgga aactatggaa caacctgtgc
     8281 tcctggaagt gtttaccaac aaaaacaagg atgcacgtat gttgaagaat tattatcatc
     8341 aattaaaaca gaaataaatt atgccaacac aaagagagtg gacaaccatc agagaatacg
     8401 acgatattct ttttgattat tataatggaa ttgcccgtat cacaatcaac cgtgaacgtt
     8461 atcggaatgc atttaccccg actaccactg ccgaaatgag tgatgcattg cgcatttgcc
     8521 gtgaagaagc ggatattgat gtgattgtaa ttaccggagc cggtgataag gcgttctgtt
     8581 cgggaggcga ccagaatgtg aaaggacgtg gcggatatat cgggaaagac ggtgtgcctc
     8641 gtttgagcgt attggatgta caaaagcaaa tccgtagtat tccgaaacct gtgattgctg
     8701 ccgtgaacgg ctttgccatt ggtggcggac acgtgctcca tgtagtatgt gatttatcca
     8761 ttgcttcgga aaatgccatt ttcggtcaga caggtcctcg cgtgggtagt tttgatgccg
     8821 gattcggtgc atcttatctg gcgcgtgtgg taggacagaa gaaagcacgt gaaatttggt
     8881 tcctttgccg taagtataat gcacaagaag cattggatat gggattggtg aataaggtag
     8941 tacctttgga acagctggaa gatgaatacg tgcaatgggc ggaagaaatg atgttgctta
     9001 gtccattggc tttgcgcatg attaaagcgg gattgaatgc cgaactggac ggccaggcag
     9061 gtattcagga gttggcaggt gacgcaacat tactttatta cctgacggat gaagcacagg
     9121 aaggaaagaa tgcgttcctg gagaaacgta aaccgaactt caaacaatat ccgaaattcc
     9181 cttaaaataa taggctaatg aaagactgat tgtgcagtaa ttagcagatt gaaaagatat
     9241 tcattatgga ttgtaagata gatattattc ctcggttgct tcatttcaag caacccgcgg
     9301 gaacttcccg gggaacatat actacacgaa aagtctggta tcttcacttt acttctcctg
     9361 attttccggg tagagtggga attggagaat gtgcgccttt gcctgcgtta agttgtgatg
     9421 atctccctga ttacgaagat atattaataa gaacttgccg gcaagtagag gaagaacagg
     9481 gaaaattgga taaagatggt ctatgcaagt atccttccat cttatttggc ttggaaacgg
     9541 ctatctggca tttctttgca gggagttggg ctttgtccga tacggctttt tcacgtggag
     9601 aggtagggat tccaatcaac ggcctgatct ggatgggaga ttttgaaaac atgttatccc
     9661 agatcgagaa aaagatggaa gccggattcc gttgcgtcaa actaaagatt ggcgctatcg
     9721 actttgaaaa agaattggca ttactacgtc atattcgtac ccatttctct tctaaagaaa
     9781 tagagttgcg tgtagatgca aacggtgctt tctctccggg tgatgcaatg gaaaaactga
     9841 aacgtctgtc agaatttgat ttacattcta tcgaacagcc gattcgtgcc ggacaatggg
     9901 aagaaatggc tcggctcact tctgaatctc cgttgccagt agcattggat gaagagctga
     9961 taggatgcaa cacgctggaa gaaaaaaaga aactgctggc aaccatccgt ccgcaatata
    10021 tcatcattaa accatctctc cacggaggaa tatgtggagg ggatgaatgg attatggaag
    10081 cggaaaagca acatatcggc tggtggatca cttccgcttt ggagtccaac attggtttga
    10141 atgctatcgc ccattggtgt gcaacattca ataatccgtt accacaagga ttgggaacgg
    10201 gtatgctctt tactgacaat atagaagtgc ctcttgaaat cagaaaagat tgcctgtggt
    10261 tttgtaaatg atggtattta gtggtattta aaggatattc tgatgatatt cgatcgacaa
    10321 caacagcgct tgctactgga aggaaaagaa tacacttttg aagaaataag ccaactgata
    10381 gcaggaggag cagaagctca ttctcctgct tattgggatt tatatctttt cctgaacgaa
    10441 tggtttaatg attctcctgt tattacagtt catacatcgg gctccacggg tatacctaaa
    10501 gaactgatgg tacgcaagga tcaaatgatg caaagtgcac gtctgacttg tgaatttctg
    10561 aatttgaaga aaggtgagtc ggcattatta tgtatgaatc ttcgttatat cggtgcaatg
    10621 atggtggtcg tacgttcatt ggttgcaggt ttgaatctga ttgttcgtcc tgcttccggt
    10681 catccgttgg cggatataaa agaacctttg agatttgtgg caatggtccc attgcaagtt
    10741 tataacacga tgcaggttcc cgaagaaaaa gagcgattaa aacaaacgga tattctgatt
    10801 ataggaggcg gagccgttga tgaggctctg gaaacggaga taaaccatct tccgactgcc
    10861 gtttactcca cttatggcat gactgaaact ttgtcgcata ttgcccttcg tcgtctgaac
    10921 ggagcatcgg cttcagaaca ttattatcca tttccttcag tgaaattgtc tttatccgca
    10981 gagaatacat taatcattga tgcccctttg gtatgtgacg aaacattgca gaccaatgac
    11041 attgcacgta tctatcccga tggaagtttt atgattctag gccggaaaga caatgtgatt
    11101 aacagtggag gaattaagat tcaagcagag gagatggaga agttgctccg cccgtttatt
    11161 cctgtgtcct ttgtcattac ttcagttccg gatcagcgct tagggcaggc tgtcacttta
    11221 ttattggcag atcagcccga cacagaagaa atcggaaata aactacatga aatactggaa
    11281 ccttattatc gtcccaagca tatattgaca atagaatcca ttccgcaaac agagaacgga
    11341 aaaataaacc gggcagagtg tcgcatctta gccaaacaaa tgttgatgac gttttaccct
    11401 cacaccctca ccctgtctcg tcctgctccc aactaatata tactatattc ccctatatgt
    11461 catacattga tatttagttg ttcttttgtt aagctctaat gttttacaag ggctcaccca
    11521 tgtgaacaaa tctgtttaca accgtaaaca gatttgttca caacagatag cttatttgtc
    11581 cacactagta agcccctgct aactattaag cagagtgata taaacaacac aggactaata
    11641 catataatgc acaactgttt ttcaaaagaa aggcatatat caggaagaga acaatcaggg
    11701 gtagagtatg cacgaagaaa gaacaagagt aattgtggca tatactact
//
