LOCUS       gnlProkkaIBCGHNGI_12   18399 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBCGHNGI_12.
ACCESSION   gnlProkkaIBCGHNGI_12
VERSION     gnlProkkaIBCGHNGI_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 18:40:11
            Original ID  :: gnl|Prokka|IBCGHNGI_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 152004
            Orig. end    :: 170403
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[10000:15478]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15478
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..18399
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18399
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             328..1053
                     /locus_tag="ctg12_121"
                     /transl_table=11
                     /translation="MKVLITICARGGSKGIPGKNIKPINGKPLIGYSIDSAKKFQQLYP
                     DTEIALSTDSEEIIEVARQCGLDSDYHRPSYLANDTAGKVDAIFDVVKFYEQKKQCTYD
                     YVLDMDCTSPLRTIDDLTEAYQMIVADPEAITLFSVSPPVRSPYFNQVEKKENGYYDLV
                     KRPTTGSVFTRQSAPQVYDMNASFYFYKRDFFTRGFNDVNTDHSLVYVMKHACFDLDEP
                     LDFEILSYLMENNKLKLSL"
     CDS             1050..1985
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 59.2; E-value: 7e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_122"
                     /transl_table=11
                     /translation="MNILFVGIGSIAKKHIAALKHLGVEATLYALRSSRQSEPYPGVVD
                     IYSYDELSQFHLDFIIISNPTSEHAATIRRLMHFQVPLFIEKPLFADCKHDDIVAYIKQ
                     HRILTYVACDMRFLDALRFVHDYVDARYDQLKINEVNVYCGSYLPAWRPGIDYRTCYSA
                     IPELGGGVHIDLIHDIDYVYWIFGQPSNSYAIWRNVSSLGIRAYDYANYNLEYPTFCVN
                     IVLNYYRCDAKRTMEIIFDDCTWTLDMLKNQVTDHKGKVVFQSEQQGSETYVAQMAYFL
                     SLLKKKQTMSFNSSEEAYQVLNICLKNERC"
     CDS             1972..2715
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     122.5; E-value: 3.5e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_123"
                     /transl_table=11
                     /translation="MKDVKSKVIIVTGGNGLIGREIVKELKEYEACVVSADIAFNTYAD
                     KNEFRLDLSDNDSIDQLVRFTLDNYGRIDGVINAAYPHTKDWGDYFYEDEPFEHFKRNV
                     ELQMNSMFYIDQQVAKVMIKQNFGSIVNFGSIYGIVGNDFTLYEDYNGTSPIDYCAVKG
                     GIINMTRYQASYLGKYNVRANCVCPGGIFDHQRKEFLKNYNHRCPMKRMGNPDDIAPLC
                     LFLVSDGAKYITGQIIAADGGWTAI"
     CDS             2728..3174
                     /locus_tag="ctg12_124"
                     /transl_table=11
                     /translation="MITSIPVEKIVLLLEKQLNSNFTLVDAEKTILEHSFSKVMEKLEY
                     CFLHTDNKYYSCMTGCGGKKTYFNPFHSCQYTIFLYYYARIIAMQTEGRLLADKLYYLN
                     KMMNGVDLYHQIELPAVWGCEHPMGSIMGRATFGEYFFFIKVVP"
     CDS             3381..4421
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 143.6; E-value:
                     1.2e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_125"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-11, bitscore:
                     37.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYSHIIPQSFPIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTD
                     GDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDRVEDIHHQRDLRMRLVPILDEENHI
                     CEIINLEHYVTKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSYG
                     LNHISVTVNYLGDQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNS
                     DLFTNINFEDFFLHFCQHDADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYAN
                     AGIYLIKRKLLGLIPDDIFFNATDFMDKLIEQGYKVIRYPISGYWLDIGQHDELARARE
                     MVKHLK"
     CDS             4441..5394
                     /locus_tag="ctg12_126"
                     /transl_table=11
                     /translation="MYKIAVIGAGQLGSRHLQGLKLSKLKSDIWVVDNNSNSLQIAQQR
                     YEEGEVNSNQTIYYLQLIEQLPTELDLVVIATSSKPRLTILKSLLAKVKVTNIILEKFL
                     FTGLTDYDEAEQLLQINHVNVWVNCPRRLFDFYVEIDSMIDKQKPLVMEYTDSNWGLCC
                     NSIHMIDIFMMLSGEKTYTACFDGIIPQVKDSKRNGYIEFNGTVNVLTPNGSTLRLACV
                     DDDTVQHQMTIINGSHHIIINEPEGFMSVDGNKQPVHIKYQSQLTGAVADEILLNGNCK
                     LTTYFESSNYHKVFLKGILDVYNKVTGEMHDRCPIT"
     CDS             5372..6346
                     /locus_tag="ctg12_127"
                     /transl_table=11
                     /translation="MIDALLHNIKGDYMIWIIGTGTIALEYAKILNQLGHEFIAVGRSG
                     KNADEFIEAGAKEVVSGGLNNYLAASPTTPQKVIVATNVDQLAEVTVSLLNFGIKDILV
                     EKPGFCRPEEITPVVQLAQAKNAHVLLAYNRRFYSSVLAAEKIIKEDGGITSFNFEFTE
                     WGHVIETLDYSHNIFDNWFFANSSHVVDLAFFLGGEPQEISCFSAGELSWHKPAVFSGA
                     GITNKGALFSYQANWNAPGRWVVEVLTTKHRLYFKPMETLQIQEKGSVAIKPVEIDNQL
                     DIDFKPGFYLQTKAFVEGDYGRFCTVEKQMKHINTIYKKIVEK"
     CDS             6685..7695
                     /locus_tag="ctg12_128"
                     /transl_table=11
                     /translation="MHLLICNSNMFIPIVLTTVLNNSDQRYLIYVDIPSIYMFFDKLNL
                     PENCNLLKYPHYINWKNANKAKQFIWNQLEHIDIKSITFYHTAYGELATWLISKYSRNT
                     TIYFQSPFPSFCFKKRISLKALKLFLVYKIIYNTDIIPMDSGNNTLPSISPKFFKKNNV
                     INKNAMVDNDLVCNYVNEKLNLNNNNRSILLVTGSNITAGFCDETDYGKIINSILSALG
                     KDKFMVKCHPRFDDLLSIEKMLPAIPKYIPGNVILPLFDCYIGLCSALLIEAANVGKCS
                     ISILNLLNIDFKLKSVLKDSLEVRLKSGSTIYYPNSISELNDIVKRSCNNNITMI"
     CDS             7697..9142
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_129"
                     /sec_met_domain="Polysacc_synt (E-value: 6.1e-21, bitscore:
                     68.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRAKQLGKNTLLVFIGSFGAKIISFIMLPFYTRWLSVTDYGVVD
                     MISIYQSLLTDFLTAAISTSIFIFPKGVAFHRQKEYFSSGLIFAFFAFIVAALLFYIVR
                     SSFNLFSVSNSFTDYTVWIYIMIFITFIQTYLQQFCRSIDKMYVFTLIGILLTLCTGIF
                     SFIFIPKNGVYGYLIAMVLSNVVVAITTFFIAKLYKYVSLKSFNKISLKEMLKYSIPTI
                     PNVLMWWVLGSLNRPILEGTVGLSGIGILAVAQRFPNAASLVFSIFGNSWQISVLEEYK
                     MNDFPLFFNRVLAIFSIITCLGVLILSYISDWLVTFIVGNNFLSSSTYIPCLSLALFFL
                     CMNTIISPIFSAVRKSKYYLYSSIWSAVLTIGLNILLIPLIGIMGACISIVCSHALMTL
                     LRVKYTLIFVSVYLKEQYLFLGLLAVAFIVALSIGDSLMFRTMALLVAFLGVALVIRNF
                     DKRLNIKFLAIKLFKNKIKFKQS"
     CDS             9139..9990
                     /locus_tag="ctg12_130"
                     /transl_table=11
                     /translation="MITLRGLFRDLKFLIGCFVYLVKHYSLFSGLKFQGRQERIVYLLC
                     NGPSLKNDMETIKKLKGVDFIVVNFMANDSLFWEIKPQYYTLMDPLFFTNRRENRYMER
                     LEVLFDSFNRIDWEMIIFLPIQYEKSFREFSKINNPKIKIMVLNTFSSYVASDNVRHFC
                     YRKGYAMPNAQTVAIESIFAMLNMGYSTIYLYGVDHTFLEGLKVNDKNELVHVYQHFYE
                     NEPKIIPVTDAFGYHNSLTKELQTIVNIFASHEQCRKYADHLGANIYNLTKGSQIDSYE
                     RR"
     CDS             10001..11512
                     /NRPS_PKS="Domain: AMP-binding (16-408). E-value: 9.2e-71.
                     Score: 230.4. Matches aSDomain:
                     nrpspksdomains_ctg12_131_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     210.7; E-value: 5.1e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_131"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-73, bitscore:
                     241.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKIDVLERLSTKMAKYLDQNCFCIKDKYYTYRELSILTAKIQ
                     QEIRNQYTETTPVGLVNNDDIYTYASILALWYEGLAYVPLHPLQPIARCIDIIEQVNIQ
                     LIIDSTEMSRYVDKYNVLYPQNNSNTDVVFPVINNIDDEALCYILFTSGSTGKPKGVQL
                     NRRNITSFVAAFENAGIVLSHEDRCLQCFDLTFDVSVQSYLMPLLNGACVYTLPLDCMK
                     YACSADLIERYKLTFGAMAPSMVRFLKPYFDELDMSSLKKCILTAEASNLSLVKDWKKC
                     AYNAELYDFYGPTEATIYCTYYKLPDDINQTKNRNDILFIGKPMSGIKAVLISPDGIVL
                     NKGIGELCVAGEQVTPGYWQLFEKNKEAFLTISIDNKDYRFYKTGDLCQFDKDGDLEYI
                     GRIDFQAKVQGYRVELGEIECKIREFTKCDTVVLAIKEDNNDDILVGFVESRLVDEKQV
                     YVYLREQLPPYMIPKSIISLAQFPLNNNGKIDRKQLIEIFKTHNK"
     aSDomain        10049..11224
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_131_AMP-binding.1"
                     /evalue="9.20E-71"
                     /label="ctg12_131_AMP-binding.1"
                     /locus_tag="ctg12_131"
                     /protein_end="408"
                     /protein_start="16"
                     /score="230.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AKYLDQNCFCIKDKYYTYRELSILTAKIQQEIRNQYTETTPVGLV
                     NNDDIYTYASILALWYEGLAYVPLHPLQPIARCIDIIEQVNIQLIIDSTEMSRYVDKYN
                     VLYPQNNSNTDVVFPVINNIDDEALCYILFTSGSTGKPKGVQLNRRNITSFVAAFENAG
                     IVLSHEDRCLQCFDLTFDVSVQSYLMPLLNGACVYTLPLDCMKYACSADLIERYKLTFG
                     AMAPSMVRFLKPYFDELDMSSLKKCILTAEASNLSLVKDWKKCAYNAELYDFYGPTEAT
                     IYCTYYKLPDDINQTKNRNDILFIGKPMSGIKAVLISPDGIVLNKGIGELCVAGEQVTP
                     GYWQLFEKNKEAFLTISIDNKDYRFYKTGDLCQFDKDGDLEYIGRIDFQAKV"
     CDS_motif       10436..10489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_131_0001"
                     /evalue="1.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_131"
                     /protein_end="163"
                     /protein_start="145"
                     /score="26.6"
                     /tool="antismash"
                     /translation="CYILFTSGSTGKPKGVQL"
     CDS_motif       11030..11107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_131_0002"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_131"
                     /protein_end="369"
                     /protein_start="343"
                     /score="23.8"
                     /tool="antismash"
                     /translation="IGELCVAGEQVTPGYWQLFEKNKEAF"
     CDS_motif       11192..11257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_131_0003"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_131"
                     /protein_end="419"
                     /protein_start="397"
                     /score="32.0"
                     /tool="antismash"
                     /translation="YIGRIDFQAKVQGYRVELGEIE"
     CDS             11517..11762
                     /NRPS_PKS="Domain: PP-binding (11-76). E-value: 9.5e-10.
                     Score: 30.8. Matches aSDomain:
                     nrpspksdomains_ctg12_132_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_132"
                     /sec_met_domain="PP-binding (E-value: 2.4e-09, bitscore:
                     30.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHDIYTSLNQILGKIIGDTKLDLNELTTTDEISGWSSLVQTQL
                     VVEIEKHFNCRLTLRDIMKIDKNISSIVTLIDNKLQ"
     aSDomain        11550..11744
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_132_PP-binding.1"
                     /evalue="9.50E-10"
                     /label="ctg12_132_PP-binding.1"
                     /locus_tag="ctg12_132"
                     /protein_end="76"
                     /protein_start="11"
                     /score="30.8"
                     /tool="antismash"
                     /translation="QILGKIIGDTKLDLNELTTTDEISGWSSLVQTQLVVEIEKHFNCR
                     LTLRDIMKIDKNISSIVTLI"
     CDS             11759..12376
                     /locus_tag="ctg12_133"
                     /transl_table=11
                     /translation="MKILSLIRTLKSVLYAYDSDQWEKRVGALGKDSYLRGPISCANPS
                     LIFVGNHSHIFGQANYIIRNGKFIVGDYTGIAQGLTVITGNHISEKGKLFNDCLQLDEQ
                     DVIIEDDVRIGAFVTILPGVKIRRGAIIGAGTVLRFSIPPYAVVTGNPAKIVGFRMNPQ
                     EALEHEAALYPEEKRLSADELFDNYEKYYFNRMSEIIEYLKV"
     CDS             12388..12588
                     /locus_tag="ctg12_134"
                     /transl_table=11
                     /translation="MKITAVIPIRSGSQRVKDKNLRAFADTNLMELKIKNLLQVPELTS
                     IVVNTNSELAIEIVNKSYGGG"
     CDS             12585..13070
                     /locus_tag="ctg12_135"
                     /transl_table=11
                     /translation="MTTHRREEYYASSQCSGSEFFRHLGEVTDTDLFVYCPCTSPFIKP
                     ETVSQCINQFISTSDYDCLATVSSVKEFLWLDGDPMNYDPAHAPNSQDLPDVVALNFGV
                     TVVRKEDLIKNSNIIGKNPQFVKTSDIESIDIDTPLDFYIAEQLYKKLVIEKKRLLE"
     CDS             13133..13870
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_136"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.9e-13, bitscore:
                     42.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIIAIIPARYQSSRFPGKPLADIFGRPMIWWVYNQVIKVKEFL
                     EVYVATDDQRIADVCSNYGMKFIMTQSNHPTHVHRIHEVSDNIAADYYVVVCGDEPLIS
                     PDIIEAVFPSQDVDNSHMYVGGLCRYFTEPAEVIDPANIKIVTNDSDECVLLSRAPIPF
                     PYKTVLFKYKKVVGVECYNKQALDFFVSTPKGYLENIEDVTLQRFLENKIHIKYKLVDS
                     VSLSVDTPRDLEKVKEIMVTKQA"
     CDS             13874..15478
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 58.9; E-value:
                     7.9e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_137"
                     /sec_met_domain="HMGL-like (E-value: 3.6e-21, bitscore:
                     69.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKVLMLDCTLRDGGYVNDWDFGHSTITGIYKRLEAAGADYIEV
                     GFLDDRREFDINRSIMPSTEAINKIFGSVKKGKAIPVAMIDFGTCSLDSIGSCDSTFID
                     GIRVIFKKEKIDQALPFCKAIKEKGYKLFIQAISITAYSDIEMLEYVNRINEIKPYAFS
                     IVDTYGLLDNSSMARYFYLIDNNLDPSIKMGYHEHNNFQLGFSNTIKFLEKSTKRTLVA
                     DSTVYGMGKSAGNCASELLAMHLNEYYGGHYDLNQLLEIVDTDLMPIYQKHYWGYKYDF
                     YIASMQRCHPSYVQYLLKKSTLSVSSINEILSSIPEEIKLLYNKQWIEQAYLDYQNRAK
                     DDTEALQQLKVELEAASDKPVLIIGPGNTVKEQKKGVELFISGNDPVVFSVNFYTKLYS
                     IDYTFISNAKRYAKFVDIQHGDSIGSKLILTSNVTACDYMPDYVLNYESLLNKESENPD
                     NALVLLLKALIRIGITEVYLAGFDGFTNTPNDYYDRDYELSSTKDESYNDLLSDDLSKI
                     NQSIRLHFITESLYDVR"
     CDS             15465..16130
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 118.3; E-value: 6.2e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_138"
                     /transl_table=11
                     /translation="MMSDKQTIKAVLFDLDGTLLNTSEGIACSVLHTLSVMQLPSISSD
                     EVSTFIGPPIQESLKRHFRLSDEDVQKGADIFRAYYKDCALFKAALYPGIIDLLKQLKQ
                     KGFLIGVATYKREDYAMDILKHFGILEYCDVVHGADNDNKLRKSDIVYLCISEMSVDNS
                     EVVLVGDTYHDLEGAEEADIHFIAVTYGFGFRESVRELSNKNVVGVADNPMEIEGLLK"
     CDS             16320..16592
                     /locus_tag="ctg12_139"
                     /transl_table=11
                     /translation="MSNQVPYNLFSKWYKDTRKKIIPVLVLGAPSTESEMPESPSPLPE
                     QKSELDPRLFCHTELRILVDIRMSNGVHISQKNLSNEGKQSKIGS"
     CDS             16635..16997
                     /locus_tag="ctg12_140"
                     /transl_table=11
                     /translation="MYSSEDLERFYFQYQTEALPHGESLQSFCVKNKVPYNIFQKWYRD
                     TRKKVVEVQVDGAPVIGHEEQSSAIDQPQPVSPGRTDHPVRIWVEIRISNGLHLSQKNL
                     SYQDLVRMVEKLEGLC"
     CDS             16991..17326
                     /locus_tag="ctg12_141"
                     /transl_table=11
                     /translation="MLSVTGLNHFYYVRDFTDMRCKHSRVLSIIRERLHREPNDGDVFI
                     VMSRNRRIVRMFSFDNRSYSLFEKKFVAGYQFMKVERNGADTVYRIAWKDVVLILENPI
                     VKTLKIR"
     CDS             17399..18397
                     /locus_tag="ctg12_142"
                     /transl_table=11
                     /translation="MIDLQDIIKTKRELLSRETYSRNPINYSAGMAEDQKDRYIQYLAE
                     QNQDLRLTGDAMKLVLEDFMAQMKELKAQMSSMQSKHADLENRLSEEHKLRKSAERKIK
                     SLQEKLDYAHQEHFGDRRQKIQSKAKISDSDRRKEKDDYDGTDDTLRTDSVGHVPSQEL
                     KEPSGKDRDLSNRPDGYKTMGVAGEATEHPSDLTKVPGRIIERRMVRVFSFRTFLTEEC
                     FEMVHYAEPGKKPKWGYFPSEGHPEVVTSFEGTRATPEFLQAIAYEVYVKNVTFGLLHQ
                     WLTDTGMTISKNTLRNWLKKGKTYLDELVCVLKSIALEKDSIVNCDETWCKV"
ORIGIN
        1 acggtcctga ccacaaagcc tccctcaatc ccgaggaact caaacaaatg gtgatggcta
       61 ttcgtaacat tgagcgagct ttaggtaatg gcatcaaaca gcctaatgag agtgagaaac
      121 aaatttcaga agtggtgctc aaacgtattg tggcggctac accaataaag aaaggtgagg
      181 tgctctcggc ggataatatg actgtgaaac gctgtgccgt tggtttgaaa gcttctttat
      241 gggatttggt aaacggaaga acttccacat gcaattatga tactgatgaa cctatcgtga
      301 tttaaagcta ttttacagac ttataatatg aaagtactca ttacaatttg tgcccgtggt
      361 ggttccaaag ggattccagg taaaaatata aaacctatta atggtaaacc ccttattggt
      421 tattccattg actcggctaa gaaattccaa cagctctatc ccgataccga gatagctctt
      481 tctacagatt ccgaagaaat tattgaagtg gctcgtcaat gtggattgga ttctgattac
      541 catcgtccca gctatttggc caatgatacc gcaggtaagg tagatgccat tttcgatgtg
      601 gtgaaattct acgaacaaaa aaaacaatgt acctatgact acgtgctaga catggactgt
      661 acttctccac ttcgtactat cgacgacttg actgaagctt atcagatgat agtcgctgac
      721 cctgaagcta tcacgttgtt ctctgtaagt ccccctgttc gtagccccta ttttaatcaa
      781 gtagaaaaaa aagagaacgg ttattatgat ttggtaaaac gtcctactac aggatcagta
      841 ttcacgcgtc aatcagctcc gcaggtttat gatatgaatg cctcgttcta tttctataaa
      901 cgcgactttt ttactcgtgg gttcaatgat gtgaatacgg accattcatt ggtttatgtg
      961 atgaagcatg cttgctttga ccttgatgaa cctctcgatt ttgagatact ctcttatctg
     1021 atggagaata ataaactgaa attgagttta tgaacattct ctttgtaggc attggttcaa
     1081 tagccaagaa acatatagct gctttgaagc atttaggcgt agaagcaacg ttgtatgcac
     1141 tccgttcttc acgtcaatcg gaaccgtatc ctggtgtggt ggatatttat agttatgatg
     1201 aattgtctca gtttcattta gatttcatca ttatttctaa tcctacctca gagcatgccg
     1261 caaccattcg tcgtttgatg cactttcaag tgcccctctt tattgaaaaa ccgctgtttg
     1321 cagactgtaa gcatgatgat attgtggctt atattaagca acatcgtata cttacctatg
     1381 tagcttgtga catgcgcttt ctcgatgcac tccgttttgt gcatgactat gttgatgcac
     1441 gctatgatca actcaaaatt aacgaagtca atgtttactg cggatcttat cttcctgctt
     1501 ggagacccgg tatcgattat cgtacgtgtt acagtgctat tcctgaatta gggggcggtg
     1561 tgcatatcga cttgattcac gacatcgatt atgtatattg gatttttggt caaccatcaa
     1621 acagttatgc tatttggcgc aatgtttctt cattaggtat tcgggcttat gattatgcaa
     1681 attataactt ggagtatcct actttttgtg ttaatatcgt gctcaattat taccgttgtg
     1741 atgcaaaacg taccatggaa ataatatttg atgattgtac gtggacattg gatatgctca
     1801 aaaatcaagt gacggatcac aaaggcaagg ttgtgttcca atccgagcaa caaggcagtg
     1861 aaacctatgt agcccaaatg gcttatttcc ttagtctcct caaaaagaaa caaacgatga
     1921 gttttaactc tagcgaggaa gcatatcaag tattaaatat ttgtttaaaa aatgaaagat
     1981 gttaagagta aagttatcat cgttaccgga ggtaacggtt tgataggacg cgagatagta
     2041 aaagaactca aagagtatga agcctgcgtg gttagtgcag atatagcatt caacacatat
     2101 gctgataaaa acgaatttag acttgacttg agtgataatg attctattga tcagttggtg
     2161 agatttacac ttgataatta tggtcgcatt gatggggtga tcaatgctgc ttatcctcat
     2221 acaaaggatt ggggtgacta tttttatgaa gacgaacctt tcgaacactt caagcgcaat
     2281 gtggagcttc agatgaattc tatgttctat attgaccagc aagtcgccaa ggtaatgata
     2341 aaacaaaatt ttggttccat tgtaaacttt ggatctatct atggcatcgt aggaaatgac
     2401 tttacccttt atgaggatta caacggcact tcaccaatcg actactgtgc tgtcaaaggt
     2461 ggtattatca atatgactcg ctatcaggcc tcctatcttg gcaagtacaa tgtgcgtgcc
     2521 aactgtgtat gtcctggtgg aatttttgat caccaacgta aggagtttct taagaattac
     2581 aatcatcgct gtccaatgaa acggatggga aatcctgatg acattgctcc gctttgtctt
     2641 tttttagtat ctgatggtgc taaatatatt actggtcaga ttattgcagc cgatggtgga
     2701 tggactgcta tttaactcat agactatatg attacatcta ttccagtaga aaaaatagta
     2761 ttgttactag agaagcaatt gaacagtaac tttacgcttg tcgatgcgga gaagacgatt
     2821 ctggaacatt ctttttcaaa ggtaatggaa aagttggaat attgtttcct acatactgat
     2881 aataagtatt actcttgcat gaccggatgt gggggtaaaa aaacttactt taatcctttt
     2941 cactcctgtc aatataccat ttttctatac tattatgctc gcattatagc tatgcaaacc
     3001 gagggtagat tactagccga caaactgtac tatcttaata agatgatgaa tggtgttgat
     3061 ctctaccatc aaatcgagct cccagctgta tggggctgtg agcatccaat gggttccatt
     3121 atggggcgtg ccacctttgg cgaatacttc ttttttatca aggttgtacc gtaggaggtg
     3181 accacaacac ttatcctgtg ataggtcatc atgtccgtct ctttgcaaat tccacagtgt
     3241 tgggtgaaag ccacattgga aataacgtat ggattggtgc cggtgcatta gttaagaata
     3301 ctgatatacc agataactca ttagtgttcg gtcaatcacc caatctgata ataaaacaac
     3361 gaaaagatat ttagataatt atgaattact ctcatattat ccctcaatcc tttcctatta
     3421 ttgatgccat tcgctgcatc aatgagattc acaatgaacc gctggtgctc tttgtggtag
     3481 atgagaacaa aaggatgcaa ggtaccctta ccgatggtga tgtgcgtcgt gccttgatta
     3541 aaggtataga tgtggatgct cctattagtg aggccatgca tcgtaatttt aactttttac
     3601 gtcgcggagt gaacgataga gtggaggata ttcaccacca acgtgattta aggatgcgtt
     3661 tggtacccat acttgatgaa gaaaatcata tttgcgaaat catcaatttg gaacattatg
     3721 taactaaatt gccaattgat gctgtattaa tggccggtgg taagggggaa cgccttcgtc
     3781 cgttaacgga gaaaactcct aagcccctaa ttaaggtagg tgacaagtgc atcattgatt
     3841 ataatattga tcgtttgctt tcatacggtt tgaatcatat atctgtaacg gttaactatc
     3901 ttggcgacca gattgaggaa catttccggg aggaacgcga tggggtgaag atagttactg
     3961 tgcgtgaacc gaaatatcta ggtaccattg gcagtatcaa gttcgtggaa actttttaca
     4021 atgatacggt gctggtaatg aactcagatc tctttacgaa tattaatttt gaggactttt
     4081 tccttcattt ctgtcagcat gatgccgaca tgagtgtggc agctgtgccc tacgtagtga
     4141 aggtgccata cggtgtgttc aatctcgaag gacgagaaat aaagggcgtt accgagaaac
     4201 ctaccatcag ttattatgca aacgccggta tataccttat caaacgcaaa ttgcttggcc
     4261 ttattcctga tgatatcttc tttaatgcca ctgacttcat ggataaactc atagaacagg
     4321 gatacaaggt gattcgctat cctattagtg gatattggct ggatattggt cagcatgatg
     4381 aattggcgag agcaagagag atggtgaaac atttgaaata aattaaaaaa acaacataca
     4441 atgtataaaa ttgcagttat tggtgccggg caattgggta gtcgtcattt acaaggactc
     4501 aaattgtcca agctgaaatc tgatatttgg gtggttgata ataattcaaa ttcacttcag
     4561 atagcgcaac aacgttatga agaaggtgaa gtgaatagta atcaaactat ttattactta
     4621 caacttatcg aacaattacc tactgagtta gatctagtag tcatagctac cagttcgaaa
     4681 ccacgattaa cgattttaaa aagtttactt gcaaaagtga aagtgaccaa tatcatttta
     4741 gaaaaattct tgtttacagg actgactgat tatgatgaag ccgaacagtt gttgcagatc
     4801 aatcacgtca acgtatgggt aaactgtccg cgacgtctat tcgactttta tgtagaaatc
     4861 gattcaatga tagataagca aaagcctctt gttatggagt atactgattc taattgggga
     4921 ttatgttgca attccataca catgatagac atatttatga tgctgtcagg agaaaagact
     4981 tataccgcct gttttgatgg aattatacct caagttaagg acagcaaacg taatggatac
     5041 atagaattca acggcaccgt taatgtatta actcctaacg gaagtacttt acgactggct
     5101 tgtgtggatg atgatactgt tcagcatcag atgactatta tcaatggctc tcatcatatt
     5161 attattaatg agccggaagg atttatgtct gttgatggta ataaacagcc cgttcatata
     5221 aaatatcaga gccaattgac tggtgcagta gctgatgaaa ttctgctaaa tggtaattgc
     5281 aaactaacta cttatttcga gtcgtcaaac tatcataaag tattcctaaa aggtatactg
     5341 gatgtttata ataaagtaac gggcgagatg catgatagat gccctattac ataacataaa
     5401 aggtgattat atgatttgga ttataggaac aggaaccatt gcattggaat atgcaaagat
     5461 attgaatcaa ttgggacatg aatttatagc agtaggacgt agtggtaaga atgcagatga
     5521 gtttattgag gccggagcta aagaggtagt ttctggtgga ttaaataatt acctggcggc
     5581 ttctccaact actcctcaaa aggttattgt agctacaaat gtagatcagt tggctgaagt
     5641 cactgtaagt ttgctgaact ttggtataaa agatattttg gtggaaaaac ctggattttg
     5701 ccgtcccgaa gaaattacac ccgtagttca gttagcacaa gctaaaaatg ctcatgttct
     5761 tctcgcatac aaccgtcgct tctattccag cgtattggct gctgagaaga ttattaaaga
     5821 agatggtgga ataacctctt ttaattttga gtttactgag tgggggcatg taattgaaac
     5881 attggattat tcgcataata tcttcgataa ttggttcttc gccaattctt ctcatgtagt
     5941 agatcttgct tttttcctag gaggcgaacc ccaagaaatt tcttgtttta gtgcagggga
     6001 attgtcatgg cataaacctg ctgtattttc aggagcaggt atcactaaca agggggctct
     6061 attctcgtat caagctaact ggaatgctcc cggtcgttgg gtggtagaag tattgactac
     6121 aaagcatcgt ttgtatttta aaccgatgga aactcttcag atccaggaaa aaggtagtgt
     6181 ggctatcaag cctgttgaaa tagataatca attggatata gattttaaac ctggttttta
     6241 tttacagact aaggcgtttg tagagggaga ttatggaaga ttttgtacgg tggagaaaca
     6301 aatgaaacat ataaatacta tttataagaa aatagtagaa aaataatgta agcactcaaa
     6361 ttaatactca atttaaaaaa aatctatctt cgctgcaggt aaattttaaa aaatatgtat
     6421 tgtaatgaaa atttagaaag gttttgcttt cagtactaaa caaaggcctt ttccccatgg
     6481 gaacccctct agtcgtccta tgtaaagaat aaaattccta taacactcta aagtgctctt
     6541 tcgaaatgga atatcctaaa ttgagcgctt atacaactaa aactattttt taattaatta
     6601 ttaatcgatc agttctatgc tttgttcatt tttagcgagg tggaagagtt tgatagttta
     6661 catttgtagt aaaagataaa taaaatgcat cttttgattt gtaatagtaa tatgtttatt
     6721 cctatagtac ttactacagt actaaataat tccgatcagc gttatttgat ttatgttgat
     6781 atacctagta tatatatgtt ctttgacaaa ttaaatttgc cggaaaattg taatcttcta
     6841 aaataccctc attatattaa ttggaagaat gctaataagg caaaacaatt tatatggaat
     6901 caacttgagc atatagatat taaaagtatt acgttttatc atacagcata tggtgaactt
     6961 gcaacttggc taatttctaa atatagtaga aatacaacga tttattttca atcacctttt
     7021 ccttcttttt gctttaaaaa acgaatttcg ttaaaggcac taaaactgtt tctagtctat
     7081 aagattattt ataatactga tatcatacca atggattctg gtaataacac attgccttct
     7141 atttctccta agttttttaa gaagaataat gtaattaata aaaatgctat ggtagataat
     7201 gatttagttt gcaattatgt aaatgaaaaa cttaatttga ataataataa ccgttccatt
     7261 ctattagtta caggttcgaa tattacagcc ggtttttgtg atgaaactga ttatgggaaa
     7321 attataaatt ctatattatc tgctttagga aaggataaat ttatggtaaa atgccatcca
     7381 agatttgatg atttattatc gattgagaaa atgcttcctg ctattcctaa gtatattcca
     7441 ggcaacgtca tccttccatt gtttgattgc tatattggat tgtgttctgc tttgctgatt
     7501 gaagctgcaa atgttggtaa atgcagtatc tctattttaa atctactgaa tatagatttt
     7561 aaattgaaat cagttttaaa agattcgtta gaagtgagac taaaaagtgg atctactata
     7621 tattatccta atagtattag tgagcttaac gatattgtga aacgttcatg taacaataac
     7681 ataactatga tataaaatgg ggagagccaa acagttagga aagaatacgc tgttagtttt
     7741 tattggaagt tttggcgcaa aaattatctc atttatcatg ttgccgtttt acacgcggtg
     7801 gctaagcgta actgattatg gcgtagtaga tatgatatca atataccaat cgcttttaac
     7861 cgattttcta acagccgcta tttcaacttc aatatttata ttccccaaag gggtagcatt
     7921 tcatcgtcaa aaagaatatt tttcttcagg cttgatattt gctttttttg catttatagt
     7981 agctgcactt ctattttata tagttagatc aagttttaat ctattcagcg taagcaatag
     8041 ttttacagat tatactgttt ggatttatat aatgatattt attacattca ttcagacgta
     8101 tttgcaacaa ttctgtagga gtatagataa aatgtatgta tttacattga taggtattct
     8161 tctcacatta tgtactggta tcttttcttt tatatttata cctaaaaacg gcgtttatgg
     8221 atatcttatt gccatggtat tgtcaaatgt agtagtagcc attacaactt tttttatagc
     8281 aaaattatat aaatatgttt ctttaaaatc cttcaataag atttctttaa aagaaatgct
     8341 taaatactct attccaacta ttcctaatgt tttaatgtgg tgggtgttgg gttctttgaa
     8401 tagacccatc ttagaaggta cagtgggact ttctggtatc ggtattttag cagtagcgca
     8461 acgttttcca aatgcagctt cgttagtgtt ttctatattc ggtaattcat ggcagatttc
     8521 agtattggaa gaatacaaaa tgaacgattt tcccttgttc ttcaatcgtg ttttagccat
     8581 tttttcaatc attacatgcc ttggagtgct catcctatct tatatttccg attggctggt
     8641 aacttttatt gtaggcaata atttcttatc ttcgtctact tatataccgt gtctttcatt
     8701 agctctcttt ttcttatgca tgaatacgat tattagtccc atattctctg ctgtacgaaa
     8761 aagtaagtat tatctgtatt caagtatatg gagtgctgtg ctgactatag gccttaatat
     8821 tttgttgatt ccgttaattg gcatcatggg agcttgtata agtattgttt gttctcatgc
     8881 actcatgaca ttgttgaggg ttaaatatac tttgattttt gtttctgtct acttaaaaga
     8941 acagtatttg ttcttaggtt tgttagctgt tgcttttatt gtagcgttat cgataggcga
     9001 ttctttgatg tttcgaacaa tggcactttt agtagcattt ctcggcgttg ctctagttat
     9061 tcgtaatttt gataaacgtc ttaatattaa atttttagct ataaaattat tcaaaaataa
     9121 aatcaaattt aaacaatcat gataacatta cgtggattat ttcgagattt aaaattccta
     9181 ataggatgtt tcgtgtatct tgtaaaacat tactctcttt tctctggcct taaatttcaa
     9241 ggtcgccaag aacgaatcgt gtatttgtta tgtaatggac cttctttaaa aaatgatatg
     9301 gagactatta aaaagctgaa aggagttgat tttattgtgg taaactttat ggccaacgat
     9361 tctctttttt gggagattaa accacaatac tacacattga tggatccgtt gttttttaca
     9421 aataggagag agaatagata tatggaaaga ttggaggtac tatttgattc cttcaatcgt
     9481 attgattggg aaatgataat tttcctaccc atacaatatg aaaagtcctt tcgtgagttt
     9541 tcaaagatta ataatccaaa gattaaaatt atggtattga atacgttctc atcatacgtt
     9601 gcctcggata atgtaaggca tttctgttat agaaaagggt atgctatgcc taatgcgcaa
     9661 acagtggcta ttgagtctat ttttgctatg cttaatatgg gatatagtac tatttatctt
     9721 tatggtgttg atcatacatt tctcgaaggt ttgaaagtaa atgataagaa tgaacttgta
     9781 catgtatatc agcattttta tgaaaatgaa ccaaaaataa tacctgtaac cgatgctttt
     9841 ggttatcata attcacttac taaggaattg caaaccatag tcaatatttt tgcttcccat
     9901 gaacagtgtc gcaaatatgc tgatcatctg ggtgctaata tttataattt gactaagggg
     9961 tcacaaattg atagttacga acgtagataa atgagagaag atgaataact ttaagattga
    10021 tgtgttggag agacttagta caaaaatggc taagtatcta gatcaaaatt gtttttgtat
    10081 taaggataaa tattatactt atcgggaact ttctatttta actgcaaaga ttcaacagga
    10141 gataagaaat cagtatactg aaacgactcc ggtaggattg gttaataatg atgatattta
    10201 tacctatgct tctatcttgg ctttgtggta tgaaggactg gcttatgttc ccttgcatcc
    10261 cttgcaacct attgctagat gtattgacat tatcgaacaa gtgaatattc aattgattat
    10321 tgattctaca gagatgtcac gctatgtaga taaatataat gttctatatc cacaaaataa
    10381 ttccaataca gatgttgtat tccctgtcat taacaacata gatgatgaag cattgtgcta
    10441 tattctattt acttctggta gcacgggtaa gccaaaaggt gttcaattga acagacgtaa
    10501 tattacttca tttgttgccg cttttgaaaa tgctggtatc gttttatccc atgaagatag
    10561 atgcttgcaa tgctttgatt tgacatttga tgtgtctgta cagtcttatt tgatgccttt
    10621 attaaatgga gcatgtgtct atactttacc attagattgt atgaagtatg cttgttctgc
    10681 cgatttaata gaacgataca aacttacatt tggtgctatg gctccttcta tggtcagatt
    10741 tttaaaaccg tattttgatg aattggatat gtcatctctt aagaaatgca ttctaactgc
    10801 cgaagcttct aatctctcct tggtgaaaga ttggaaaaaa tgtgcgtata atgctgaact
    10861 ttatgatttt tatggcccta cggaagctac tatctattgt acttattata agttgcctga
    10921 tgacatcaat caaactaaaa accgaaatga tattctgttt attgggaaac ctatgagtgg
    10981 aataaaagct gttcttattt cacccgatgg gatagtcctg aataaaggaa ttggtgaatt
    11041 gtgtgtggct ggtgaacaag ttactcctgg atattggcag ctttttgaaa aaaataaaga
    11101 agctttcctt actatatcca ttgataataa ggattataga ttttataaaa cgggtgattt
    11161 gtgtcagttt gacaaggatg gagatcttga atatattgga agaattgatt ttcaggctaa
    11221 ggttcaaggt tatcgtgtag aacttggtga aattgaatgt aagattagag agtttactaa
    11281 atgtgataca gtagtgcttg ccatcaagga agataataat gatgatattc tcgttggttt
    11341 tgttgaatca agattagttg acgaaaagca agtctatgtt tatttgcgtg aacagttacc
    11401 tccatatatg ataccaaaat ctatcattag tcttgctcaa tttccactaa ataacaatgg
    11461 taagattgat agaaaacaat tgattgaaat ttttaaaact cataataaat aaaataatgg
    11521 aaagacatga tatttatact tctctaaacc agattttagg gaaaataata ggtgatacaa
    11581 aactggatct aaatgagttg actactacag atgaaatttc tggttggagt tcactcgtac
    11641 aaactcagtt ggtcgttgaa attgaaaagc atttcaattg ccgtctgact ctaagggata
    11701 ttatgaaaat agataagaat atatcttcca ttgtaacatt gatagataat aagttgcaat
    11761 gaaaatcctt agtttgattc gaactcttaa gtcggtgtta tatgcttatg attctgacca
    11821 atgggaaaaa cgcgtagggg ctttaggaaa agatagttat cttagaggac ctatatcttg
    11881 tgctaatcct agtttaatat ttgtaggcaa tcactctcat atatttggac aagctaacta
    11941 tatcatcaga aatgggaaat tcatagttgg tgattataca gggatagcac aaggattgac
    12001 tgttattaca ggtaatcata tttcagagaa aggaaaactg tttaatgatt gtttgcaact
    12061 ggatgagcaa gatgttatta ttgaggatga tgttcgcatc ggtgcttttg tgactatttt
    12121 gcctggagtg aaaattagga gaggtgctat aataggtgcc ggaacagtat tgcgtttttc
    12181 tattcctcct tatgctgttg ttacaggtaa tcctgctaaa attgtgggat tcagaatgaa
    12241 tccgcaagaa gcgcttgaac atgaagcggc tctttatccg gaagaaaaac gcttgtccgc
    12301 agatgaatta tttgataatt atgaaaagta ttactttaat cgaatgagtg agataataga
    12361 atatctaaaa gtataaaata caaaataatg aaaattactg ccgttattcc tattcgcagt
    12421 ggatcacaac gtgtcaagga taaaaacttg cgtgcctttg cggatactaa tttgatggaa
    12481 ctgaaaatta aaaatcttct gcaagttcct gaacttacat ctattgttgt aaacactaat
    12541 tcggagttag caatagaaat tgttaataaa agttatgggg gggggtgact actcaccgtc
    12601 gtgaagagta ttacgcctct tcacaatgta gcggaagtga attttttaga catttaggtg
    12661 aagtgacaga taccgatctt tttgtctatt gcccctgtac ttcgcccttc attaaaccag
    12721 aaactgtatc tcagtgtatt aatcaattta tttctacttc ggattacgat tgcttggcta
    12781 ctgtttcgtc tgttaaagaa tttctttggc ttgatggtga tccgatgaat tatgaccctg
    12841 ctcatgcacc taactcccag gatctccctg atgtggtggc gttgaatttt ggtgtaacag
    12901 tagtcaggaa agaagatctt atcaaaaact ccaatatcat cggtaaaaat cctcaattcg
    12961 tcaagacaag cgatattgag tccattgata ttgatactcc tcttgatttc tatattgctg
    13021 agcagcttta taaaaagtta gttatagaaa agaagaggct gctggaataa gttttgggat
    13081 tgattggtat ttcgctgaat gatgcagata taaagaataa ctcattatat ttatggataa
    13141 gattatagct attattcctg cgcgatacca atcatcacgc tttcctggaa agccattggc
    13201 tgatattttt ggaagaccaa tgatttggtg ggtttacaat caggtaatta aagtaaaaga
    13261 attcttagag gtttatgtag ccacagacga tcaacgaatt gctgatgtgt gctcgaatta
    13321 tggtatgaag tttatcatga cccagtcaaa tcatccaact catgtgcata ggattcatga
    13381 ggtaagtgat aatattgcag ctgactatta tgttgtagtt tgcggtgatg aacctttgat
    13441 tagcccggat ataatagagg ctgtttttcc ttcgcaagat gttgataata gtcatatgta
    13501 tgttggtggt ctctgtcgat acttcacaga accagcggaa gttattgatc ccgcaaatat
    13561 taagattgtg actaatgatt cagatgaatg tgtattgtta tcaagagcac ctattccgtt
    13621 tccttataag actgtgcttt ttaaatataa aaaagtggtg ggtgtggaat gctataataa
    13681 acaagcttta gatttttttg tctccacacc taaaggctat ctggagaata tcgaggatgt
    13741 aacacttcag cgatttttgg agaataagat tcacatcaaa tataaattgg tggattcagt
    13801 atctctttct gttgataccc ctcgagactt ggagaaggta aaagaaataa tggtgacaaa
    13861 acaagcttga actatggaaa aaaaagtatt aatgttagat tgtacgctac gtgatggtgg
    13921 ctatgtcaat gattgggatt ttggtcatag tactattacg ggtatttata agcgattgga
    13981 agcagcaggt gctgattata ttgaagtggg tttcttggat gacagaagag aatttgatat
    14041 aaatcgttcc atcatgccaa gtacagaagc tatcaataaa atctttggtt ctgtaaaaaa
    14101 aggaaaagcg atacctgtag caatgattga ctttggcact tgttctcttg atagtatagg
    14161 ttcttgtgat tctactttta ttgatggtat tcgagttatc ttcaagaaag aaaaaataga
    14221 tcaagctttg ccattctgta aagctattaa ggaaaaaggc tataagctct tcatacaagc
    14281 catttcaatt acagcctata gtgacattga aatgcttgag tatgtaaatc gcatcaatga
    14341 aattaaacct tatgcttttt ctattgtaga cacttatggt ttgcttgata atagcagtat
    14401 ggctcgatat ttctacttga tagacaacaa tttggaccct agtattaaaa tggggtatca
    14461 tgaacacaat aacttccaat tgggctttag caatacaatt aaatttttgg agaaaagtac
    14521 caaaagaaca ttggtggcag attctacggt ttatggcatg ggaaaaagtg ccggaaattg
    14581 tgccagcgaa cttttagcga tgcatttaaa cgaatattac ggagggcatt acgatttaaa
    14641 ccagttgttg gagattgttg atacagattt gatgccgatt tatcagaaac attattgggg
    14701 ctacaaatat gatttctaca ttgcttcgat gcaacgatgt catccgtcct atgtccagta
    14761 tcttctcaaa aagagtacat tgtctgtcag ctcaattaat gaaattcttt cctcaatacc
    14821 tgaagaaata aagttgcttt ataacaaaca atggatagag caagcatatc tcgattatca
    14881 gaatagagcg aaggacgata ctgaggcttt acagcaattg aaagttgaac ttgaagcagc
    14941 gagtgacaaa cctgtattga taattggtcc gggcaatact gtcaaggagc aaaaaaaagg
    15001 ggtggagtta ttcatttcgg ggaatgatcc agttgtcttt tctgtaaatt tctatacaaa
    15061 actttattct attgattata cttttataag taatgccaag cgttacgcta agtttgtgga
    15121 tattcagcac ggtgacagca ttggctctaa actgattctt acatctaatg ttaccgcatg
    15181 tgactatatg cctgattatg ttctcaatta tgagtcactg ttgaataaag aatctgaaaa
    15241 tcctgataat gctcttgttt tgttgcttaa ggctttaata agaattggaa tcacagaagt
    15301 atatcttgca ggttttgatg gatttaccaa tacacctaat gattattatg atcgcgatta
    15361 cgaactttca tcaactaaag atgaaagtta taatgatctt ttgtcagatg atttatctaa
    15421 aataaatcag tcaatccgtc ttcatttcat tacagaaagt ttgtatgatg tcagataagc
    15481 aaactattaa agcggtcctg tttgatttgg atgggactct tttgaataca agtgaaggaa
    15541 tagcatgtag tgtcttgcac acgctgtctg taatgcaact cccctctata tcctctgacg
    15601 aggtatcaac atttataggc ccccctattc aagaatcttt aaaacgtcat tttagattat
    15661 cagatgaaga tgttcaaaag ggggcggata tatttcgtgc ctattataaa gactgtgctt
    15721 tgtttaaagc agctttatat ccaggtatca ttgacttgtt gaaacagttg aagcaaaaag
    15781 ggtttcttat tggagtagct acatataagc gtgaagatta tgctatggat attctaaagc
    15841 attttggtat tttagaatat tgtgatgtcg ttcatggtgc agacaatgat aataaactcc
    15901 gtaagagtga tattgtttat ctttgtatat ctgaaatgtc agtggataat agcgaagtgg
    15961 ttttagtagg tgatacatat catgatttgg aaggagcaga agaggctgat attcatttta
    16021 ttgctgtaac ttacggtttt ggttttagag aaagtgtaag agaactttct aataaaaacg
    16081 tggtgggagt agctgataat ccaatggaaa tagaggggct gctgaagtga atttcataat
    16141 agaattctat ctcgttagcg tccaaaaatg acgtatagga taaccgataa aaaagtcaga
    16201 cctttgcttt cgttaaatca aaatccaagt ttatgtatag ttacaatgat tttgagcgtc
    16261 tatttttgcg ctataaattg gaagggattc ctgctggtgt ttctacataa aaattttgta
    16321 tgtccaacca agttccttat aacctatttt ccaaatggta caaggatacc cggaagaaga
    16381 taattcccgt tctggttttg ggtgctccct caacggaatc ggaaatgccg gaaagtcctt
    16441 cgccactccc ggaacaaaag tcagaattgg atcctcggct tttttgtcat accgaacttc
    16501 gaatcctggt ggatatccgc atgagcaatg gtgttcatat cagtcagaaa aatttaagca
    16561 acgaaggtaa gcagtcaaaa attggctcat aatttaaacc tctatcttcg ctgcgaacaa
    16621 aaattttaga atttatgtat agcagtgaag atcttgaaag gttttacttt cagtaccaga
    16681 ccgaggcttt gcctcatgga gaatctctcc aatcgttttg tgttaagaac aaagttcctt
    16741 ataacatctt tcagaaatgg tacagggata cccggaaaaa agtagttgaa gtccaggttg
    16801 atggtgctcc tgtaatcggt catgaggaac aatccagtgc cattgatcaa cctcaaccgg
    16861 tatcaccagg cagaactgat caccctgttc gtatttgggt tgagattcgt atcagcaatg
    16921 gcttgcattt gtcccaaaag aatttaagct atcaggattt ggttcgtatg gtagagaaac
    16981 tggaggggtt atgctgagtg ttaccggtct gaatcatttt tattatgtcc gtgatttcac
    17041 cgatatgcgt tgtaagcaca gccgtgtgct gtctatcatt cgtgaacggc ttcaccgtga
    17101 gcccaatgat ggagacgtct ttatagtcat gtctcgcaat cgcagaatag tccgtatgtt
    17161 ttcatttgat aatcgttcat atagtctgtt cgaaaagaag tttgtagcag gctatcagtt
    17221 catgaaagtg gagcggaacg gggcagatac tgtttatcgg attgcctgga aggacgtggt
    17281 tttgattctt gagaatccta tagttaaaac attaaaaatc agataatcaa tctatttatc
    17341 cacttgtggc tttgcgatta ttttattacc tttaatgctg taactcaaag atttaagtat
    17401 gatcgatctg caagatataa ttaaaacaaa acgagagttg ttgagtaggg aaacctactc
    17461 acgcaaccct ataaattata gcgcaggtat ggcagaggat cagaaagacc gatacataca
    17521 ataccttgct gagcaaaatc aggatctcag gttgacaggt gatgccatga agcttgtttt
    17581 agaggatttt atggctcaga tgaaagaact gaaggctcag atgtcatcca tgcaatcgaa
    17641 acatgctgac cttgagaatc ggttgtcaga agagcataaa cttcgcaaat cggctgaacg
    17701 taagataaaa tcacttcaag aaaaacttga ttatgcccat caggaacatt ttggtgatag
    17761 acgtcaaaag atacaatcta aagctaaaat aagtgattca gaccgccgga aggagaagga
    17821 tgattatgat ggaaccgatg atacgcttcg cacggattcg gttggtcatg ttccatccca
    17881 agagttaaaa gagccttccg ggaaagaccg tgacttgtcc aatcgccctg acggttataa
    17941 aacgatgggg gtagccggag aggcgacaga gcatccttct gatttgacaa aggttcccgg
    18001 tcggatcatt gaaaggagaa tggtacgggt gttcagtttc cgtactttcc ttacggaaga
    18061 atgttttgag atggttcatt atgcagagcc tggtaaaaag ccgaagtggg gctatttccc
    18121 ttctgaaggc catccggagg tagtaaccag ttttgaaggc actagggcca ctcctgaatt
    18181 tctgcaggct atcgcctacg aagtttatgt aaagaatgtg acttttggtc ttcttcacca
    18241 atggctgaca gatacgggca tgaccatttc taaaaacacg ttgcgcaact ggcttaagaa
    18301 aggtaagaca tacctggacg aactggtctg tgtattgaag tctatagctt tggaaaaaga
    18361 ttcgatagtg aactgcgacg agacctggtg taaagtgcg
//
