LOCUS       gnlProkkaKNICABMM_36   14855 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KNICABMM_36.
ACCESSION   gnlProkkaKNICABMM_36
VERSION     gnlProkkaKNICABMM_36
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 00:35:56
            Original ID  :: gnl|Prokka|KNICABMM_36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14855
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14855
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3220:4855]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3221..4855
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14855
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14855
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             689..1450
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 76.8; E-value: 3.3e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKAYSILNSTPEEARETAGRFLEKS
                     GLDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGMKGFFF
                     RSTLFPPTPSALRGSNLDLLATEIETILKLQ"
     CDS             1459..1911
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMASPAEAPETKSRPAP
                     SQEKQEKNSAGSPKQQIRKSTDEASGPDEYRQRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPNMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             1899..2564
                     /locus_tag="ctg36_3"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYTPGKKEKEE
                     EGTSCGTGSGDVMGATQFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGIAPVITSDDLLNAGDVLLNLDGAQMNEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELIDQYIGNDGNVLPVKRKKKEGQPEHAWRQFL"
     CDS             2986..3180
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             3221..4855
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.1e-21, bitscore: 68.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKTNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCE
                     YMASYGTSEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEE
                     EAIPKKLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTR
                     VFRKVEPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVF
                     HITTNATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIR
                     EVSEEYLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKT
                     DKQLAQFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKAR
                     YFNSCYIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPS
                     CRSCWAGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQM
                     ERMYFQANDITLGAFHAYVKEQQDVAP"
     CDS             4852..7029
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 284.4; E-value:
                     3.1e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.2e-36, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVSVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGHYYELINNQLIAMG"
     CDS             complement(7125..7883)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MLPGQTWNRILNNETVIDKDLKSVLIAKLCTLEPVDSLEDKHNVL
                     GFSYNGIPCKGLGWASEAMENTLALGFRQKDAWDNGNYDVDISLLDEDGNELPLTSGCK
                     HVVSPDGVETHRDFLLKNINMPTNGKVLSKRTAKLFPHLKFAEQASDQLDKIKDSAVVQ
                     QIYWRLSDLERVAANSTSPVSPEKFKYKTTPESETRSRLPQLKILFSDGETRLCSWHSR
                     FTPGAGRIHFCPNESEQIFYIGYIGEKIAD"
     CDS             complement(8041..9165)
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MIKEIRLKNFKVFEEESFNIKPLTLITGVNGMGKSTLIQSLLFLK
                     QNYELGYLSNPKKKLRLKHDFVNLESAGDICYTFAEEKSVCISIKENNGNEYQWVLDTS
                     EAGSEEVGYTYTGSDIHGLSLFDDRFIFLEAERWGPKAQYNKSEARAYNTSLGIQGELT
                     PAYLNNALSVNEEIGIKEMRHPNLKEEQIQLTENVNAWMAQIMQVPSLKANTTEIDKDK
                     IRLEYGMAGTKGKKYSALQVGFGFTYCLPVIVALLRAKADDLLVFENPEAHLHPAAQVE
                     LGKLMALAAGKGVQIIIESHSDHILNSLRLARKEKVISQEDLNVIFVQRDFGAGDDMEV
                     TYIDEIQITDEGKLNERPKNFFDSWDDVLTRLID"
     CDS             complement(9172..10038)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MANLPIQLIYLDGSKTPWTVIDGVQRISSLHKFLQNEFVLDGLEY
                     FSKECEGMSFSSIPFYLRNRIESTNIVAYVINPGTPDAVKFNIFKRINKIGKQRNREEL
                     RNAFFQGSVSKCIAELAESHEFLQATHKMMSQKGMSDRELVCRYFAFRLLRPFFDTTET
                     MDDFLDKGMDALSALPENDFERETARFKTVMQRCYDVLGDITFINIKATRKRINKNLFD
                     AFSYTISRLNDNEYQSLLRQSDRLEKEYKRLFEEKGFLCGKELRKTSTEAVRKRFDTMD
                     RFIRKFT"
     CDS             10534..10860
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MSYPNDSTMKKRILFSVMCAAIAAGAFAQGQGQGLAGINEATSLM
                     TSYFDPATKLCYAIGAVLGLVGGIKTYGKFSSGDPDTSKTAASWFFACIFLIVAATILR
                     SFFL"
     CDS             10865..11191
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MEYPVNKGAGNSVEFKGLKSQYLFVFAGGLTVVLLAVVILYLAGV
                     DQWICIPFGIVSGGLLVWVTFRLNARYGEYGLMKLLAGKRHPRYLIHRKRVFRLFTKRK
                     KKQP"
     CDS             11188..13725
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MRNVLKAETLERKFPLLSVENGCIVSKDADLTVAFEVELPELYTV
                     TADEYEAMHASWIKAIKVLPEHSVVCKQDWFVKETYRPKTGGEEQSFLARSYERHFNER
                     PFLNHRCYLYLTKTTRERNRRQSDFSTLCRGFLLPREITDKEAAERFLEAVEQFERIMN
                     DSGHVRLRRLDTDEVTGTKEHPGLVEKYFSLSLEDGTAVLQDICLKPGRMRIGDKRLCL
                     HTLSDTEDLPGKLSTDMRYERMSTDKSDCRLSFAAPVGLLLSCNHIYSQYVFIDSAQEI
                     LQMMEKNSRNMLSLSKYSRSNAVNQEWTEMYLDEAHAKGLLPVRCHCNVIAWAEDADEF
                     RRIRNDTGSQLAMMECTPRYNTVDTPVLYWAGIPGNAGDFPAEESFYTFLEQAVCLFAG
                     ETNYRNSPSPFGIRMADRQNGIPVHVDISDLPMKRGIITNRNKFILGPSGSGKSFFTNH
                     LVRNYYEQGTHILLVDTGNSYQGLCRMIHDRTRGEDGIYITYEEDNPISFNPFYTDSGQ
                     FDVEKRESIKTLILTLWKREDEAPTRAEEVALSGAVNAYIRKISGDRSVRPDFNGFYEF
                     VSVDYRRMIEEKRVREKDFDIDGFLNVLEPFYRGGDYDFLLNSDKELDLTNKRFIVFEL
                     DNIGSNKVLLPVVTLIIMETFIAKMRRLKGVRKMILIEECWKALMSANMSEYIKYLFKT
                     VRKYFGEAVVVTQEVDDIISSPIVKEAIINNSDCKILLDQRKYMNKFEHIQRLLGLTDK
                     EKGQILSINQANHPGRSYREVWIGLGGTHSAVYATEVSEEEYFTFSTEESEKLEVQRLA
                     EESGGDLEAAVRRMAEKRREEQRQTSTFKQERL"
     CDS             13722..14078
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MRNRPFVKLAVCLISMAALILQSCSESGTDRDKLCGSWTSVEGKP
                     DVLVYKEGEAYKVTVFARSGKTRVLKPKTYLLVEENGNLFINTGYRIDVSYNEATDVLT
                     FSPNGDYVRKEERP"
     CDS             14075..14704
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MRAKSLLIGTVFALCGTAADAQWVVTDPGNLAQSIINMSDNIAHT
                     SKTAVNTAESFAETVKIYEQAKRYYDQLKAVNNLIQDARKVRDIILMVGDVSDIYVTNF
                     GKMMNDGNFSPRELDAIAFGYARLLEESNGVLQDLRQVINVSTLSMTDKDRMDVVDRCY
                     YEMRRYRNLVSYYTNKNIAVSYLRARKKNDLDRVMRLYGDETSKYW"
ORIGIN
        1 gggcgggcaa gttggtcctt gtcggacaaa agactttttg tcggacaagg acacaacttg
       61 ctctgttcgt ttgaacagag aatcctcctt cgtcggattg ctgcgcgacg ttcacggcgt
      121 gctgtggtcc gatgaagcgt gttcctctcc attgacggat tttgattttg caaaattaca
      181 gggtagtaat cggttggtaa atagcgtttt atatgacgtt tgatgacatc tgacgacatc
      241 tgatgtcagg ccggggaaat gttggcggaa gtctcaaaaa tagccgttac ttttggcaca
      301 gtgcatgagg gcatacattg gaacattgtc ctgtaaggtg tattgcttgc ctgccacagg
      361 cggtacatgg cacggatgca atatcatccc tgtaggtaca ttgccataca tgttgcacgg
      421 tgatcctgca tggcgggtta cattgcatga atgcaataca gtacgggttg cattggactc
      481 cgtattacat gaatgcaatg caccttatat ggcaataccc tccggtaacc ggcaatacat
      541 tggtgcaata gggtacgcaa tgtattcatg caagcgggca ggcagtgcgt cattgccata
      601 taccgacaga tgcattgtca tgtaatgaaa caggaaaaac atatccggac agatatgaaa
      661 ccaaattata cactctaaat tcaagcctat gaagaaggaa cctttatttg tcgctttgag
      721 caaccagaag ggcggtgtgg gaaaatccac gttcaccgtc ttgctcgcca gttacttcca
      781 ttacctgaag ggatataacg tgcttgtggt ggattgcgat tatccgcagc acagtatcag
      841 caccatgcgg gactgggaag tgggaaccat tgaaaagaac gtgcatctgc aaaaccagct
      901 ggtggaacag ttcgggacaa gcggaaggaa agcctacagc atcctgaact ccactccgga
      961 ggaagcccgg gaaactgccg gccgtttcct tgagaaatcg ggactggact atgaccttgt
     1021 cctttttgac ctccccggaa ctgtgaatgt gcccggtgtc ttccggtccg taatcaatat
     1081 ggactatgta ttcactcccg tcacacagga gagaatggtt atgcggagca gcatggcttt
     1141 tgtccttgcc atccgggaat acatgcaccg tcataaggat gtgcccttgc gtggcatcta
     1201 tatgttctgg aaccggatgg acaaacgtgt gtccaaagac ctgtataaca gctacactga
     1261 aattttccgc tcgctgaaat tgccggcgat ggaaaccgtc attcccagtg cggagcgcta
     1321 caataaagac ttcgggatga agggattttt ctttcgcagc accttgttcc ctccaacccc
     1381 ttccgcattg aggggcagca atctggactt gctggcaaca gagatagaaa ccatactgaa
     1441 acttcaataa gaacaatcat ggctaccaaa agaagaacgg attaccaggt ggatgaggag
     1501 gctttgaaac gtatgatggc cggggatgta acagcattgg acaaaatggc ttctcccgct
     1561 gaggctccgg aaacaaaaag ccggcctgcc ccttcccagg agaagcagga gaagaactcc
     1621 gccggttctc ccaaacagca gataagaaaa tccacggatg aggcatccgg cccggatgaa
     1681 taccggcaac ggtttctgaa agagaggctg tccggttcaa gaaggcagac ctatattcac
     1741 gatgctttgt ataggactgt tgccaaatta ttgcctgtca ttgcaccgaa tatgtcagtt
     1801 cccatgtttt taggcagtgt cctgtcggat cacctggaaa gatatcagga tgttatcaat
     1861 gaaatatata accaggaagc aaatcaaaac cctttggaat ggaagaaata gtttatttgt
     1921 cagtaaggat cggctgtgcc ggctacttgt tatacaagtt atggaatcag aaaaaacgga
     1981 tccgtaagat ttgcgggctg ctctataccc ccgggaaaaa ggagaaggag gaagagggaa
     2041 catcgtgcgg tacaggatcg ggtgatgtga tgggggctac ccaatttgtc tatctggacg
     2101 aaaacgcggg tacgtttgcc gccccctaca tgagccagcc gttggaaacc gggaacgatt
     2161 atctcggaga ggaagaggcg gtgccggaga atgaggtgga gtgcgggctc cctctggaag
     2221 agatgagact gttgaaagag gaacaggaaa ggctggacga acaggctccc ggcacggaag
     2281 gtatcgctcc ggtaatcacg tccgatgacc tgctcaatgc cggcgatgtg ctgcttaatc
     2341 tggatggcgc ccaaatgaac gaggagaaaa aacgccgggc tgctgtcacc ttgcatgcca
     2401 tccgggaaac ggatatgttt gaactgattt catcccaggt ggagaataaa agcctgattg
     2461 aggagctgat agaccaatat atcggcaatg acggaaatgt attgccggtg aaaagaaaga
     2521 aaaaggaagg acagccggaa catgcctgga gacagtttct ctgaacccgg cggcaatcag
     2581 tccgatacga aaggaagagg ctttggaagc acctgccttg taccgctatc atggttgcct
     2641 gttcccggtt cctttgtcat acctggctct ttaaatgtcc atatattttg attattcggt
     2701 tggtaacgga ttcctttccg gaatcatata gaagctaaga tgttaatgaa aaataattca
     2761 ttacgtttat cctatctttt tctaagaaaa atattgtgtt tttgaatgga atctgtatat
     2821 ttgagacaga tttcaaaaat gaattataga gccgtgattt atcaggaaaa acgaatgtca
     2881 gtatcgcggc tatgggattt gaataaccgg taagctatat cggcattgca atattttaaa
     2941 ggagtgaaat gttgcaagta tgaactaact ccaattttaa aggctatggg aaaacagatt
     3001 gccaaactag gtatccgtcc ggaagacctg aaagacaaga cagtcacttc ggaacagttg
     3061 gaaaagacga aaggcgggaa agccgccggg tctgaagagt gtgtatgcta ctgcggttgc
     3121 tataccgatg actccgcttt cggtgtagat ttcaactggt ggtcaagaga ctgggattga
     3181 ttcctgcatt gtacgatgct ttgtaaacag attagccact atggaaaaac aaaaaacgaa
     3241 taagtttccc ctggtcaaat tgttcacagt tgacggggcg tcctgttatt tatatgacgg
     3301 cagagcgaac atgttcctgt cgctgtccga gactgagaag aaccttgtct gtgaatacat
     3361 ggcgtcgtat ggaacttctg aaggagagcc ttgcccggcc tccttccctt ccggtgccgc
     3421 cgctttcatc gcccgtctta acggaaacgg catcctgctt ccgggtcccc tggaagcgag
     3481 gacaccttcc ggaatgcgtg gtgaggaaca gttatggcaa caatgggagg aggaagccat
     3541 tcccaaaaaa ctgacactgg agatgaccaa tacctgcaat ctgcgttgca ggtattgccc
     3601 ctatacaatc aacgagcaac gcggacaagg aaaaatgcac gcctcccatc acttaaaaga
     3661 ggaggatgcc cggaaagcca tttcggatta tttccatgaa tacacacgtg ttttccgcaa
     3721 ggtggaaccg gaacacagga cgctgttcct gaaacggaat cctcccgccg tcagtttcta
     3781 cggcggagag gcgcttctgc gtttttccct gctggaaccg ttggtgaaat atgtgctctc
     3841 gcttccttgg gaggaacacc atatacctgc ggagaaggtc gtattccaca taacgaccaa
     3901 tgccacgctg ctgacacggg agatggtgga attctttata cggtatcatt tcaccctcgc
     3961 catcagcttc gacggtccgc cagaggagaa tgacaagtat cgtgtgttca aaaacgggca
     4021 gggtacggga acggtggtgg agcgtgccct tgacatgatc cgtgaggttt cggaagagta
     4081 cctgctgaac catgtacaca tacaggccgt gctggccccc gaatatgacc atgacaaggt
     4141 cggcagatac tttgaggggc gtagcctgaa cggttgttat ggcggggtcc gtcagttttc
     4201 ctacctggaa ttcagtgatt acagtgaaag caagaagacg gacaagcaac tggcgcagtt
     4261 caatatccgg gagcggatca aggaacttta tgaaaagggc ctctctccgg aggaacggta
     4321 ccagtatatt cttcgtgacc ccctgatcag cgcgtggctg cggtatgtgt acgccattct
     4381 gaccaaggtc ggtgacgcac cctcacacaa agccagatat ttcaattcat gctatatcgg
     4441 gcgtaccaat ctgttgcttg acacatacgg taacctgcat ctctgcgaac ggtcggattt
     4501 ctccatgcct gtcggtgagg tgaactcggg catcaaccgt accgccgtcc ggcaaatgta
     4561 ccgtgatttt tttgagaaga cagacagccc gtcctgccgt tcctgctggg ccggccgctt
     4621 ctgtaccctc tgcaccgccg cgcttatcaa gaacggtgcg gttcaggaac ctgaccgttc
     4681 catttgcaga agcttgcggc acgcacagga gaaacagata gaggacttgc tgtatatcaa
     4741 ggagtattat ccggaaattc tggaacagat ggaacgtatg tatttccagg cgaatgacat
     4801 aacgctcggc gctttccatg cctacgtcaa ggaacaacaa gacgtcgccc catgaggttc
     4861 agggtgtcct accagcatga ctccatgcag tgcggtgcgg cgtgtctccg tatggtctgc
     4921 aagcattacg gaaaggaata tgcccttgac ttcctttccg agcaatgcgg ctgcatgatt
     4981 gacggggttt ccttgcaggc cattcgtgag acggcggagg acctgggatt ccggacattc
     5041 gccgtatcgg tcggtctgtc cgaattgcag gccggatggt gtccctgtat ccttcattgg
     5101 gagcgtaatc actttgtcgt cctgtacagg attcataagg ataagtatca tgttgccgat
     5161 ccggccaaag ggacggtcat ataccggaaa gaggatttcc tgaagcgttg ggcgggagac
     5221 ggggaacagg gaatcgcctt gttgcttgaa cccacacagg ctttttatga cttctcttcg
     5281 ggcatggaac caaaagtccc gtcccctttc cgttttttat ggaggtacat agcttcttat
     5341 aaaaaagcat ttgcatcggt cgccttgacc ctgcttgtcg gcagtctcgt gcagctggtg
     5401 cttccgctgc ttgcgcaaat gatggtcgac aaaggtatcg gtcataaaaa tatcccgctt
     5461 gtctatctga ttctcggcgg ccagctggtg cttgtgctag gttctgccgc catggagttt
     5521 gtccgcaacc gtcttctgct gtttgtgggg atgcatgtca atatatcatt gataaccgac
     5581 ttcttcgcca aactgttccg cctgccgatt tcattcttcg agacaaggac caccggggat
     5641 cttttgcagc gtatcgtcga tcaccgcagg gtgcaggatt ttcttaccgg acaggttctc
     5701 tccgtcttgt tctcggtaat ggtcttgtgc atattcatgg gcgtcctgtt ttcatataac
     5761 agcttcctgt tccttgtctt tctggcggga agtatcggct acggcctgtg gaccatgtgt
     5821 ttcctgcata agcgcaagtt gtttgactat atgattttcg agaaacagtc ggccagcaac
     5881 aacaaggtat accaactcct tactttcatg caggagataa agctgcaagg cggcgaggga
     5941 aggcgcgccg gggaatggga ggcgttgcaa aaggagcttc ttgacatcca gatgaggtct
     6001 ttgagcctgc aacagttcca gcagacgggc gggatattta tcagccagtc caagaacctg
     6061 gttgtgacgg tcattgccgc cgtttctgtc attgaagggg agatgacttt gggtatgctg
     6121 cttgccgtgc aattcattat cgggcagttg aacatcccga ttgaacagct gatgcagttt
     6181 ctctataatt tccagaatgt gcggctaagc atcgagcgta tcagcgcgat tcatgggaag
     6241 gcggaggaaa gaacggggaa agagataccg gaacagccgg agatttcccg aaaggatatc
     6301 cggattgaac acctggattt taaatataac ctgcatggca aagccaaggt gctggatgac
     6361 ataacgctga ccattccggc gcaacgtacc accgccatcg tgggcgcaag cggaagcgga
     6421 aagaccaccc ttgtcaaact gttgctgggc tattttgctc ctacaagcgg aaatatcttt
     6481 ctgggggaca ctcccttgca ggattatgat atgacatcgt ggaggcacag ctgcggcgta
     6541 gtgctgcaag acagccatgt gttttccgaa tctctggcaa ggaatatagc agtggaggac
     6601 aagcatatag accgtacacg tctccggact gccgcccgtc aggccaacct ggaagagttc
     6661 atagagaaac tgcccttgaa ataccagacg atggtggggg ctgaaggcgt ggggctgagc
     6721 cggggacagg aacagcgtat ctttatcgcc cgtgcgctct ataaggaccc ttcgttcgtg
     6781 tttcttgatg aggctaccaa ctcgctggat gccaacaatg aaagaatcat taccgggaat
     6841 ctgctggatt tctgcaaagg aaggacagtc ctgatagtgg cccaccggtt aagcaccatc
     6901 cgtcatgccg acaagatagt cgttctgcat aaaggcagga ttgtcgaaga gggtacccat
     6961 gacgaattgt gcgcccgcca tgggcattat tatgagttga ttaataacca gttgattgct
     7021 atggggtgaa attgcatttt tttcaacggg cggaatacga ttaacagaca caatataccg
     7081 attatagtcc atcgctttcc aacctgaaca agcttccggc ggttttagtc tgcgattttc
     7141 tcaccgatat atcctatata aaagatctgt tcagattcat ttggacaaaa atgtattcgt
     7201 cccgcaccgg gtgtaaagcg tgaatgccag gagcagagcc tggtctctcc atccgaaaat
     7261 aagattttca attgtggcaa cctgctgcgt gtctctgatt ccggtgtcgt tttatatttg
     7321 aacttttccg gcgagacagg tgaggtggag ttagccgcca ctctttccaa atccgataat
     7381 ctccaataaa tttgttgtac aacagccgaa tctttgattt tatcgagctg atccgatgcc
     7441 tgttctgcaa atttaagatg cggaaacaat ttggcggttc gttttgacaa taccttcccg
     7501 ttggttggca tattaatatt ttttaggaga aaatccctat gcgtttcgac tccatccgga
     7561 gaaaccacat gcttgcatcc ggatgtgagc ggcagttcat ttccatcctc atccagcagg
     7621 cttatatcca cgtcgtaatt tccattgtcc caagcgtctt tttgcctgaa tcctaaagca
     7681 agcgtatttt ccattgcttc cgaggcccat cccaaacctt tgcatggtat cccattataa
     7741 gagaaaccca atacgttgtg cttgtcttca aggctgtcga caggttctaa agtgcacaat
     7801 ttggcaatca atacggattt taaatccttg tcaatcacag tttcattatt caggatcctg
     7861 ttccatgtct gtccgggaag cattcctttt cccattgctt catttgtcat acgcacgttt
     7921 gaaacgccta attccgacat tttagacaag cacctgccca ataacgagaa agcgtcttgg
     7981 gcgtccttgt tgtttgagaa tgcttttaca ctcaattcat taagatatgc ttccatgttt
     8041 tcagtcaatt agccgggtca gtacatcatc ccaactgtca aagaaatttt taggacgttc
     8101 gttcaatttc ccctcatccg tgatttgaat ttcatcaata taggtaacct ccatatcatc
     8161 gcctgctcca aagtctcttt ggacaaagat tacattcaaa tcctcctgtg aaatgacttt
     8221 ttctttcctt gccagcctta aactgttcaa tatatggtca ctgtgtgatt ctattatgat
     8281 ctgcactccc ttgccggcag ccagtgccat cagtttgccc agttccactt gtgcggccgg
     8341 atgcaggtgt gcttccggat tctcaaaaac aagcaggtcg tctgcttttg ccctgagcag
     8401 ggctacaatg acaggcaagc aataggtgaa gccaaaaccg acttgtaaag ccgagtactt
     8461 cttgcctttg gttcccgcca tgccatattc aagcctgatt ttatctttgt ctatttcagt
     8521 cgtatttgct ttcaacgaag gaacttgcat gatttgggcc atccatgcat tcacattttc
     8581 cgtcagttgt atctgctctt ctttcaggtt gggatgtcgc atttctttta tgccgatctc
     8641 ctcattaacc gacaaggcgt tgttcaggta agccggcgta agttccccct gtatgcctaa
     8701 tgaggtattg tatgccctgg cctccgattt gttatattga gctttgggtc cccaccgctc
     8761 cgcttccaga aatatgaatc tgtcatcaaa taaagaaagc ccgtgaatat cgctgccggt
     8821 atatgtatag ccgacttcct cgcttccggc ttcactggtg tccagtaccc attgatattc
     8881 gttcccgttg ttttctttga tggatatgca tacacttttt tcttcagcga atgtgtaaca
     8941 tatatctccg gcagattcca ggttgacaaa gtcatgcttc aaacgtaatt ttttcttcgg
     9001 gttggataaa taccccaatt catagttctg tttgaggaac agcaatgact gtataagggt
     9061 agatttcccc atgccattga cacctgttat caaagtcaga ggttttatgt tgaaagattc
     9121 ctcttcaaaa accttaaagt tcttaagtct tatttccttt atcatactaa actaagtaaa
     9181 tttcctgata aatctatcca ttgtatcaaa ccgtttgcgg acggcttctg ttgaagtctt
     9241 ccgcagttcc tttccgcata aaaatccttt ttcctcaaaa agccgtttgt attccttttc
     9301 aagccggtcc gactgccgaa gcaaactctg atattcatta tcattcaacc gggatattgt
     9361 ataagaaaag gcgtcaaata aattcttgtt tatccgtttc cgtgtggctt tgatattgat
     9421 gaatgtaatg tcccccagta catcgtagca gcgttgcatt acagttttaa accgggctgt
     9481 ctccctctca aaatcatttt caggcaatgc ggaaagagca tccatccctt tatccaggaa
     9541 atcgtccatg gtttctgtgg tatcaaagaa tggccgaaga agcctgaagg cgaaatatct
     9601 gcatacaagt tcccggtcgg acatcccttt ttggctcatc attttatggg tggcttgcag
     9661 aaattcgtga gattccgcca attcggcaat gcactttgac acggaacctt gaaagaaagc
     9721 atttcttagc tcctccctgt tgcgttgttt ccctatcttg tttattctct tgaaaatatt
     9781 gaactttaca gcatcaggag tgccggggtt gataacataa gctactatgt ttgtagattc
     9841 aatccggttt cgtaagtaaa aggggatgga ggaaaaagac attccctcgc attctttgct
     9901 gaaatattcc aatccgtcca acacgaattc attttggagg aacttatgga gtgaactgat
     9961 ccgctgtacc ccgtcgatta ctgtccatgg ggttttgctt ccatccaggt atattaactg
    10021 gatgggtaaa tttgccataa tggattctat aaacgaactt ctttctttgt cattccagac
    10081 atttgacatt ctttgcagtt cctccgttcc aggtatacat agtttacccg tttcaaccat
    10141 cttttccagt tgactgacgg atatgtattg caacctgatg tctacgtcat cagggctgaa
    10201 caattgcggg aaaacatact ccattctcat tataatccta attatcaatt agcctatata
    10261 tacctgtctg ggcaaaaata caacaaaaaa tcatgattgc caccttgtct tggtaatatt
    10321 ctgattttat ttgcaaaggt aaaaacatta gtcttcttaa ttttcaaaga aaagtgagca
    10381 atcacgcaga taaatcttgt atcatacaaa atgtagtatg aattaggcaa atatgttatt
    10441 gctatgacat ctgatgacat gtagtgacat ctgatgaaac cactgaacca tagcctgtta
    10501 acaccattta tcttcgccgt cgaattcaaa tttatgtctt acccaaacga ttcgacaatg
    10561 aagaaaagaa tccttttttc agtgatgtgc gcggcgattg ccgccggtgc tttcgcgcag
    10621 ggccaaggcc agggccttgc cggtatcaac gaggcgacca gcctcatgac ctcgtatttc
    10681 gaccccgcca ccaagttgtg ctacgccatc ggcgccgtgc tgggactggt gggcggcatc
    10741 aagacctacg gcaagttctc cagcggagac cccgacacct cgaagaccgc cgccagttgg
    10801 ttcttcgcgt gtatcttcct gattgtggcc gccaccatcc tgcgttcctt cttcctctaa
    10861 aggcatggag tatccggtaa acaaaggcgc gggcaattcc gtcgagttca aggggctcaa
    10921 gtcgcaatac ctgttcgtct tcgcgggcgg gctgacggtg gtgctccttg cggtggtcat
    10981 cctctatctg gcaggcgtgg accagtggat atgcattcct ttcggaattg tgtccggcgg
    11041 tctgctggta tgggtgacgt tccggctgaa tgcccgttac ggtgaatacg ggctgatgaa
    11101 gctgctggcc gggaaacggc acccgcgcta cctgattcac cgcaaaagag ttttcagatt
    11161 attcacgaaa agaaagaaga aacaaccatg agaaatgtat tgaaagcgga aacgctggaa
    11221 cgcaagttcc ccctgctgtc ggtggagaac ggctgcatcg tgagcaagga tgcagacctg
    11281 accgtggctt tcgaggtgga gttgcccgaa ctgtacacgg tgacagcgga cgagtacgag
    11341 gccatgcacg cctcctggat aaaagccatc aaggtactgc ccgaacacag cgtggtgtgc
    11401 aagcaggact ggttcgtcaa ggagacctac cgcccgaaaa ccggcgggga ggaacagagc
    11461 ttccttgcac gcagctacga gcggcacttc aacgaaagac ccttcctgaa ccacagatgc
    11521 tacctgtacc tgacgaagac cacccgtgag cgcaaccgtc ggcagagtga cttcagcacc
    11581 ctctgccgcg gcttcctgct gcccagggag ataaccgaca aggaggcggc ggagcgtttc
    11641 cttgaggcgg tggaacagtt cgagcgcatc atgaacgatt ccgggcacgt aaggctgcgc
    11701 cgcctggata cggacgaggt gaccgggacg aaagaacatc ccggactggt ggagaagtat
    11761 ttctccctct cgctggagga cgggaccgcc gtgctacagg atatctgcct caagcccggg
    11821 cggatgcgta tcggtgacaa gcggctctgc ctgcacacac tttcggacac ggaggacctg
    11881 ccgggcaagc tttccaccga catgcgctac gagcgtatgt ccaccgacaa gagcgactgc
    11941 cggctgtcct ttgccgcccc cgtggggctg ctgctgtcgt gcaaccatat ctattcgcaa
    12001 tatgtgttca tcgacagcgc gcaggagatc ctgcaaatga tggagaagaa ctcgcgcaac
    12061 atgctctcgc tgtcgaaata cagccggagc aacgcggtga accaggagtg gacggaaatg
    12121 tacctggatg aggcgcacgc caaagggctg ctgcccgtca ggtgccactg caacgtcatc
    12181 gcctgggccg aggatgcgga cgagttccgc cgtatcagga acgatacggg cagccagctc
    12241 gccatgatgg aatgtacgcc gaggtacaac accgtcgata ccccggtgct ctactgggcg
    12301 ggcattcccg gcaatgcggg cgactttcct gccgaagagt cgttctacac ctttctggag
    12361 caggcggtct gcctctttgc cggggagacc aattaccgga actcgcccag cccgttcggt
    12421 atccgcatgg cggaccggca gaacggcatc ccggtgcatg tggacatttc cgaccttccg
    12481 atgaagcgcg gcatcatcac caaccgcaac aaatttatcc tgggaccaag cggcagcggc
    12541 aagtcctttt ttaccaacca tctggtgcgc aactattacg agcagggcac gcatatcctg
    12601 ctggtggaca cgggaaacag ctaccagggg ctgtgccgca tgatccatga ccgtacccgg
    12661 ggagaggacg ggatatacat cacgtacgag gaagacaacc cgatatcctt caacccgttc
    12721 tacaccgact ccggacagtt cgacgtggag aagcgcgaga gcatcaagac cctgatactg
    12781 accttgtgga aacgggagga cgaggctccc acacgtgcgg aggaggtggc gctgtcgggc
    12841 gcggtgaacg cctatatccg gaaaatatcg ggggaccgca gcgtcaggcc ggacttcaac
    12901 gggttctacg agttcgtgtc ggttgactac cgccggatga ttgaggagaa gagggtacgt
    12961 gagaaggatt tcgacattga cggcttcctg aacgtgctgg aacctttcta ccggggaggc
    13021 gactacgact tcctgctgaa ctccgacaag gagctggacc tgacaaacaa gcggttcatc
    13081 gtgttcgagc tggacaacat cggcagtaac aaggtgctgc ttccggtggt gacgctgatc
    13141 atcatggaaa ccttcatcgc caagatgcgc aggctgaaag gtgtccgcaa gatgatactg
    13201 atagaagaat gctggaaagc gctgatgtcc gccaacatga gtgagtatat caagtatctt
    13261 ttcaagaccg tccggaaata tttcggcgag gcggtggtgg tgacgcagga ggtggacgac
    13321 atcatctcgt ccccgattgt gaaggaggcc atcatcaaca actccgactg caagatactg
    13381 ctggaccaac ggaaatacat gaacaagttc gagcatatcc agcggctgct cggcctgacc
    13441 gacaaggaga aggggcagat tctctccatc aaccaggcga accatcccgg acgttcctac
    13501 cgggaggtgt ggatcgggct gggcggtacc cattcggcgg tgtatgccac ggaagtgagc
    13561 gaggaagagt atttcacgtt ctcgacggaa gagtccgaga agctggaagt gcagcggctg
    13621 gcggaagaat ccggaggaga cctggaggct gccgtcagac ggatggcgga gaagagacgg
    13681 gaagaacaga gacaaacatc aaccttcaaa caagaacgat tatgagaaac agaccctttg
    13741 tgaaactggc ggtgtgcctg ataagcatgg ccgccctgat attacagagc tgctcggaga
    13801 gcggtacaga ccgtgacaag ctttgcggct cgtggaccag tgtggaaggc aagccggacg
    13861 tgctggtata taaggaagga gaagcctaca aggtgacggt attcgcccgc agcggcaaga
    13921 cacgcgtgct gaaaccgaag acctacctgc tggtggagga gaacggcaac ctgttcatca
    13981 acacgggcta tcgcatcgat gtgtcctaca acgaggcgac ggacgtactg actttctccc
    14041 ccaacgggga ctatgtacgc aaggaggaac gcccatgaga gcgaagtcac tcctgatagg
    14101 gactgtgttc gccttgtgcg gtaccgctgc ggacgcgcaa tgggtggtga ccgaccccgg
    14161 caaccttgcc caaagcatca tcaacatgtc ggacaacatc gcccacacct ccaagaccgc
    14221 tgtgaatacg gccgagagct tcgccgagac ggtgaaaatc tacgagcagg cgaagaggta
    14281 ttacgaccag ctcaaagcgg tgaacaacct gatacaggac gcccgcaagg tgcgcgacat
    14341 catcctgatg gtgggcgacg tgtcggacat ctacgtgacc aacttcggga agatgatgaa
    14401 cgacgggaac ttctcgcccc gcgagctgga cgccatcgcc ttcggttacg cccggctgct
    14461 ggaggagagc aacggcgtgt tgcaggacct caggcaggtc atcaacgtga gcacgctctc
    14521 catgaccgac aaggaccgta tggacgtggt ggaccgctgc tactacgaga tgcgccgcta
    14581 ccgcaacctg gtgagttact atacgaacaa gaacattgcc gtgagctatc tcagggccag
    14641 gaagaagaac gacctggacc gcgtgatgcg gctctacggg gatgaaacct ccaaatattg
    14701 gtagcctatg gtactcttgt cgatagattt cgccaacctg cataccatac tggagaccct
    14761 gtatggagaa atgatgcccc tttgcgagga gatgatggac gtgggcaagg ggcttgccgg
    14821 actgggggcg ctcttctatg tcgccgtccg cgtgt
//
