LOCUS       c00001_gnlPro..        15007 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EAJBGHLB_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:46:29
            Original ID  :: gnl|Prokka|EAJBGHLB_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 250615
            Orig. end    :: 265622
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15007
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[260615:264055]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15007
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15007
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(34..1587)
                     /locus_tag="ctg1_207"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
     CDS             complement(1621..3357)
                     /locus_tag="ctg1_208"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNPVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             complement(3378..3740)
                     /locus_tag="ctg1_209"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             4342..5238
                     /locus_tag="ctg1_210"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             complement(5489..6604)
                     /locus_tag="ctg1_211"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(6601..7008)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_212"
                     /sec_met_domain="HBT (E-value: 3.2e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 5e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(7008..8267)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_213"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.3e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8648..9679
                     /locus_tag="ctg1_214"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLNILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             complement(9652..9810)
                     /locus_tag="ctg1_215"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_216"
                     /sec_met_domain="Fer2_3 (E-value: 1.7e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.9e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_217"
                     /sec_met_domain="FAD_binding_2 (E-value: 4e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.6e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12766..13440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_218"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             13700..14653
                     /locus_tag="ctg1_219"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
ORIGIN
        1 atttatatcg attatattgt tcagatattc tatctattcc aagtcggcgt ctttcaacat
       61 tttccgtgct ttctcttttt cttccttact cagggcgagc gtatcgagtt tagcaccgct
      121 tttacgcaat tccttttctt tttccctggc ttttttaata tgttcctgca tcttctcgcg
      181 cctcaaacgt tcatcttccg gcatctgcgg cagttgggcg accaaggcac gcagatcagc
      241 gacagccaac ttcgtcttct tcccatcggg agccaacatc gtcacttcat cggcattccg
      301 gaaaaaggca tcttcacaaa ccgcttccaa gaaagggcgg taattataaa gatacttttg
      361 cgacttgtct gtcttcatat aggctgtcag gtaagtgtat ctactgaaaa tcgtcttttg
      421 caatttttcc tcctgctgaa agagtcccgg atcgacatcc cagtattgtg tactgatctt
      481 atacaggaag tgcaactggg ttgggtcttc cttccatgcg gcataataca gcttttccgc
      541 ttcgggccaa cggccgtccc tttccaaggc atcacctcgg aaggtcgtca acatattaac
      601 taggaatttt ttcggctgca tattcgtttc cgccagatcg aaaagctcat aagcccgttt
      661 acggtcgtat gtttttccca gggaagcgcc atacaacatg actgtttcca catccgtcga
      721 atctatttca taggccttct ccagcagctc gaccccatca agtgcatgac cggacatata
      781 gcgggccgcc cccgcatatt taagattcaa aaaagaagaa tcgccatcgg ccaatagacc
      841 ggtatagact gaatcggcct gcttataatc tttcgtcata tagagagcca tccctttact
      901 ctgccgtatc tggctgttat ccggattata gaacaaggcg gtatcgcaca cctgcaaagc
      961 tccctgtccg tcccccatcc gcaataacgt atttatcaga gaagatgcca cacgtacatt
     1021 ttccgggttc agctccaaag cacgggcata caaagaaaga gcgatcatcg tattaggacc
     1081 ggtccctctt ttaatatggc aatcagccag cccggtcagg atagaaggat tttcaccttc
     1141 gatggaagca agtatatgat agtgttccgt cgctcgacca taatctccca actgataata
     1201 gagacgcgcc aactgatagt tggcatagaa gttcatgctg tcggttccca atactttacg
     1261 ataacattgt ttagcttccg ctatccttcc gaaattgatc gcattcctgg caacggcgtt
     1321 caatgcatcc acattgttcg tatccatctt caagcaatga gaaaaacact gataggcctc
     1381 cttatagcgc aacagtccct catacgcctg cccgattgcc gacattgtag cataatcggc
     1441 tgaatcggca ggagtaagac tatccgcacg tgctacaact tcctgaaatt gttttttatt
     1501 gaccaattcc tgaagattaa gactctgcgc ctgtccccaa agggacagta cgcaaagaaa
     1561 cagtaataga gaaaacttac atttcataat ggtatcgtat taatgaccga ttctggtcaa
     1621 ttactgcaaa cggaaagtaa ccggaaccgt atattttacg gctacagcca tattgttttg
     1681 tacgccagga ttccatttcg gcatttcccg gatcacccgg acagcctccc tgtccagcga
     1741 aggatcgatt ccacggatca cttcaatatt tttcaaactt ccatccgtgt cgacaacgaa
     1801 agagcaagag acacgtcctt gtattccatt ctcctgagca atagccggat attttatgcg
     1861 tgttgccaga tatttcaaca acgaagcctg tccactcgga aattccggca tctgttgcac
     1921 taccgtaaag acacgaccgg acgtatcgac ttctttaatc tgcctctgca cgatacgaga
     1981 ggatgttttt ttctttccac cggaaagccg gaaagttacc ggtaccgtat atttgacatt
     2041 aaccactttg ccccgctgtt tccccggcga ccataccggc atggagttta tcacacgcaa
     2101 agcctcctca ttcagttccg gacttacccc acgaatcact tctgcctccg agatagcccc
     2161 gtcttttcca acaacgaaag aacagctaac ccgtccctct ataccatttt taacggccga
     2221 ttccgggtat ctgacattcg tcgccaggaa tttcagcaga gcaccctgtc cgccagggaa
     2281 ttccggcatt acctccacaa cggtaaacac cgggttacgg gcacgtctgg cagcctcaat
     2341 accttcctcc gatagcacat actcctcacg tttttcagca ggagaagcat caccgacaaa
     2401 agggaacggc aagatagcct ccggtagcaa gacatcggca aacgtgcttt ccgtcagttc
     2461 gtccgtgatc cgggccaatg catcgacatt gcttaaaatc agcaaggcgc ccacaaccgg
     2521 tataaaaatc aagtatttcg tcctacctat gctccgggaa cgtttcttat tcatcatgct
     2581 gatccgattt ttcagatgca gcatattaaa gttattagat aaagaggtca ccgatctatt
     2641 ggtatgtgcc aaccccaaaa ggtgatattg gtagctacga ctgtcatagc ccgattcaag
     2701 taccgtatca tccgccaaat attccagatt atgacgtacc tctcttttca acagccagac
     2761 aaacggattc acccaacaga tgatacaaac caattcgcaa ataatcacgt caatcgaatg
     2821 ccactggctg acatgcgtac actcgtgtac caaaatctca tcgatctctt tctcggaatg
     2881 gctgtcggga tgcagaaata ccagccggaa aaaagaaaaa ggaccggccg gtttattcaa
     2941 cagatgtaca cgtacgttac ggatcaaagt cacttccgac cgccgtgcca gtaacaagat
     3001 gctgctcaac tgcactaaaa aacggaacga taaggcaatt acaccgctcc aataaagata
     3061 agaaataccg ggaagtaaca aatcatgcca atttgtttgg ggaacattgc cgggggttat
     3121 tgtcgtttcg ggcaaaatgg ctgaatacat ttgtatgact tccactatcg gcccctgctc
     3181 ccggatccaa tcctgaatat tcatcagcgg ataaagcaat gacaccccga aaaatgccaa
     3241 caagatggta cggcgtagtt taaagaaggt gtccttataa aagaacagcc ggtagaaggc
     3301 ataaaggagt ataaaagcta catttacctt caagaagtag gcaaattccg gtgtcatggc
     3361 attatgtatt taacagttta ttctcgtcct ttttcaatca tatcgataat ctctttcaac
     3421 tcatcggtcg atatcttctg ttctttagca aaaaaggaga ccatttcctt gtaagagttc
     3481 tcgaaatagt tgttcaccac acttcccata aacgtccgtt tatattcctc ctgtgggatc
     3541 agcggcctgt attcgtaagt atttccgtaa cgtttcgctt tcacgtattt cttacgttcc
     3601 agattcttca caatagaagc gagtgtcgta taaggaggct taggctcttc atacttcgcc
     3661 aggatgtctt tgataaaaca cggctcgatc tgccagatcc agcgcattac atcctcttcc
     3721 tgtcttgtta atctttccat gtttctatat tattttttac gatcgtatcg caaatctacg
     3781 aatacatcgt aaatgtgcaa gaaataatgc gttaatttgt attaacaatt aataatctat
     3841 catctattcg ctgcatgcgc caaaaaggaa tttatctata agcagccaca ccaaagcatc
     3901 ccctatatta attaatgatt ttatatactc caaggggaca ctttttaagc atgggatttc
     3961 actttttccg acgataaaaa gtatttgaat tagcagtttt tacatggaat ctgtatagtt
     4021 tataaataac caacattttt tgacaaaata gctattagag cttaacatat attatccgta
     4081 aaaggtttga caaacaagct tagctagtgt atttttgcat tgtggttttt tcataatagt
     4141 attagattta aggttaacaa agttggttag gggttgtcga gatgacaatc cttaattttt
     4201 tatatacctg cctctttctt tgcacatctt gttgcctgtc atattttcat gtttttatag
     4261 tgcttttata gtacgccact gataaaaaag tcttactttt aagccgcata attgacaaag
     4321 aatctatata aatacaatat catgaaaatg ctatctttta ttttggtact ccttttaggg
     4381 ggttttatgc ctgccgggaa tcttttggct tcagacaaag aacaaaatcc tcattacatt
     4441 actgtgaaga acagccggga tctacaagcc tatttccggt atgctcccga tcgcccgatt
     4501 gtaatcagtg gacatcgtgg tggaatgcta gacggctatc cggagaactg catcgaatca
     4561 ttcgaaaaga ccttgtccta tatggaatcg tttttcgaga tagatccgcg tttgacaaaa
     4621 gacgggataa tcgtattgat gcacgacgaa accatcgacc ggacaactac cgggaaagga
     4681 aaggtttcag attacactta tgcagaactg caacaattca atctggtgga ccgaaacggc
     4741 aacgtgacag ccttcaaaat tccaacttta aaagaatgcc tggaatggag caaaggcaaa
     4801 acaatcctga atttggatat caaggatgta cctttagaag ttatggctga ttttatagaa
     4861 acagaaaagc ctgttaacgt catgtacacg gtacataacg ccagtcaagc ccgctattat
     4921 ctcgaccgga aaccggatgc gatgttttct tgctggtgta agaatcggga agaattcgat
     4981 aattatgaaa aagccggcat cccctggaaa caggtaatgg cttatgtagg cccgaagatg
     5041 aagcctgaac agcaaccact gtatgacgct ctgcaccgta acggagtcat gtgcatgatt
     5101 tccgttgctc cgacacatga tcgcgcgaaa acggaaacag agaaaaccgc cggttaccgg
     5161 tcagagatca gcactcgtcc cgacgtgatc gaaacggact atccgtacct gtttcaagga
     5221 ctcgatttaa caaaataacg cagtttaaag gactctttat agccgattaa aatctttttg
     5281 ctatttatgc tcatctgatt aacaagtatt agcgacaaaa tgcttgacaa acgctcttga
     5341 cgagtgtatc tttgcaatgt ggttttttca taatagtatt agatttaagg ttaacaaagt
     5401 tggttagggg ttgtcgtgag acagccttta attgtttata gaggttccgt ttcttctccc
     5461 acatacaaat cgtatacgaa aaagccggtc aggacagctt atagagattt cccggcaacg
     5521 cttttacctt cccgtttatt tccagttcga acaatagcat agagagttga tgtaccggta
     5581 tctccaacac tgaggcaagc tcgttgatat ggatctcatt ccgcgttcgc ataatggcta
     5641 aaaccggatt ttgttccgag gtgaatgttt ccgcctcggc gaaaaacaac tccgtttgaa
     5701 cggaagtagc cccagcttgg atatcccaac aaagagcgga gagcagatcg tccgcagaag
     5761 tgatcaggcc ggctttattt tgtcggatca aattgttgca tcctttggaa tggctgtcac
     5821 cgatgcgccc tggaaagcta tagacatccc ggccataaga gaatgcaata tcggcagtta
     5881 ccaaagagcc tcctttttct gccgattcaa ccacgatcgt acaatccgag attccggcga
     5941 caatccggtt cctccggagg aaatttggac ggtctggttc tgtaccgctg ggaaaatcgg
     6001 tcaacagacc gcccgattcc agcatttcga cagccgtatt ccgatggcag gaaggataga
     6061 tacgatccaa gccatgcgcc agcacagcaa cagtcggaag tcggttgtac aaagcgttcc
     6121 ggtgggcaca gatatcgatg ccgtaagcca atccactcac gaccaacaag tccgggatca
     6181 cttttgccaa gtcttttata agggattcgg taagctcccg accatattcg gtcgcgttgc
     6241 gagtacccac aatactgatg atacgggtcg catcaaggtt agtatttccc ttaaaataga
     6301 aaagtatagg ggcatccgga cattctctca agcgcaccgg ataatctgta tcagtcagat
     6361 aataacagga aatattgttt ttctcgataa aagccaactc tttttccgcc cgttgcaaga
     6421 tttccgggcg tttgatttcg gcagcaatat tgctgccgat accagggatc cttcctaaca
     6481 actgttgctt ttcagtaaac acagcctctg cttctcccaa agcctgcagg agatgacgcg
     6541 ccaggatatc tcccacgccg tttatcatag taaggccgat ttggtaaatc cgtttgtcag
     6601 tcatgtatgt tctattcttt ttagcatttc gtcgaaatat tcaccgcgtg tcaactttcc
     6661 gttctcaacg ataaccgact cgacgattcc tttcgtcgcc aatgcattgt cagaagccct
     6721 atatatatcc tgctcgaata cgagcttgac tcctttttta tagacattga ggcaagagat
     6781 atagctgtcg ccgctcttga gcgaggtctt atactggatt tctacccgcg atacaaatcc
     6841 gtcaacccct ttttcgtgca tctttccgaa gttctcgcca agcgactcca agaattcatg
     6901 ccgagtatgt tccatataat gctgataatt ggagttgttg accactcctt gcaggtcgca
     6961 ttcgtagtca cggaccttgt ctgtcagttt aaaaatatac tctttcatta ttcaaatacc
     7021 ttttcaagtt gaaccttttc cattttatac aatcggtcag acggccgaat cttctcgttc
     7081 accttgagag agaaccgttc acctttaacg gtctcgtcca ccggcttcaa gtccacacgg
     7141 atttcttcta tcgtctgcat aaccgcaccc gttgtcggtc cggtaatcag gatctcatca
     7201 cccactttca ggttaccgga ttccatttcg aactccgcca cgccgatctt gtcgaaatat
     7261 ttgattcctt tggcaacata cactttcttc ttagtcgcgc cggagccata tttgctactc
     7321 cactcaccca accgttgccc caaataatag ccgtcccaga atcctcggtt gaacacactg
     7381 cgcaggcgtt cgtcccaagc ggcaactttc ttttcatcga acgtgccatt gcaataagca
     7441 cgcacagctt ccttatagca ttcggtcacc aggcggacat attcgggacc gcgggcacgt
     7501 ccttcgatct tgaatacccg tacacctgca tccatcatct tattcatgaa atgaattgtc
     7561 ttaaggtctt taggcgacat aatatactgg ttttcgatat ccagttcgat attgctgtct
     7621 ttatctttta ccgaataagc acgccgacaa atctgcatgc aagctccccg gttggcggaa
     7681 gcgttcattt cgtgcaggct caggtaacat ttaccggaaa cggccataca gagagctccg
     7741 tgggcaaaca tttcgatacg gatcagttct cctttcggtc ccgtaatctg ctggtcgacg
     7801 atctgccgat agatttcatg cacctgtttc aaattcagct cacgcgccaa gacgacaaca
     7861 tcggcaaaac gggcatagaa tttcagtgct tccgcattgg aaatgttgag ctgtgtggaa
     7921 agatgcacct cctgtccgat gctgttggca tagttcatag ctgccacatc ggccgcaatg
     7981 atcgctgaaa cttccgcctc cttcgccgca tcgataatct cgcgcatcag aggcaggtct
     8041 tccccataaa taaccgtatt gacggtcaaa tagctcttaa taccgtgctc acgacaaagc
     8101 gcaacgatct tgcgcaaatc gtctgtcgta aagttattgg aagagcgcga acgcatattc
     8161 aatccttcga taccgaaata gatagaatcg gctccccctt ggatagccgc catcagtgat
     8221 tcgtacgaac cgacaggcgc cattatttca aaatctttct cgttcaagtt cttatacatt
     8281 tactggttcg ttcgcaaagg taggaataat atccgagaag aattgcatgg gtatccgttt
     8341 ctcagagcat caaaatcgtg atcaaatacc attttctata aagatttgca aaacaaccat
     8401 catactgtca ttgttgtcct ttagaatctg ttattcaata ccttaagaca tgatagtttc
     8461 tatttttaac tatcatacta ctatcatgca actatcatga tttcagctta tcattttatc
     8521 tatatcattg acagtatgac atttgtactt tctattgatc aattactaca ctttttagta
     8581 gatatccttt tatccctgtt tttagcagga aatcagtacc tttgtccccg tcattgataa
     8641 tataaatatg aaaataggta caatagattt aggcgaacgc cccgtcttct tagctccgat
     8701 ggaagacgtt acagatattt ctttccggtt gatgtgcaaa cgttttggtg ccgatatggt
     8761 ttataccgaa ttcgtttcag cagacgccct gatccgcagt gtaaataaaa cacagcaaaa
     8821 gctgaatgtg gcggatgaag aacgtccggt cgccatacaa atatatggcc gtgatgttcc
     8881 gacaatggtc gaagccgcgc aaatttgcga agccgctcat ccggacattc tcgatatcaa
     8941 tttcggttgc cctgtcaaac gagtggcagg caaaggagca ggcgccggca tgctgcgcaa
     9001 tattccactg atgctggaca tcacccgtga agtcgtcaaa gcggtgaaca tccctgtcac
     9061 cgtaaaaacc cgcttgggct gggatgccga caaccggatc atcgtagact tggccgaaca
     9121 gctacaggat tgcggtatcg cagccctttc catccacgga cgtacccggg cacagatgta
     9181 tacaggagag gcagactgga cactgatcgg tgaagtaaaa aacaatcccc gcatacaaat
     9241 tcccatcatc ggcaatggcg atgtgacttc cgccgaaatc tgcaaacaac gtttcgaaca
     9301 atatggcgtg gatgccgtta tgattggccg gggcagcata ggccgcccct ggattttcag
     9361 agaagtgagg cattatctgg atacaggcga gacattgcct gccgaatctt tttcatggta
     9421 tctgaacata ctgaaaaagc aggtggaaca aagcgtggaa cgtttggatg agcgccgggg
     9481 aattctccac attcgccgcc atttggctgc aactccgctg tttaaaggta ttgcagactt
     9541 caagcagaca cgcgtcgcca tgctacgtgc ggaaacagtg gaagcattat tcgacattct
     9601 ggattccatc cccgacaaat ttcatacagg atacggattt caaagcgact ctcaagtgtc
     9661 agaatcgatc gattgttgat ataataacag tgtgaatccg cacacagtgt caattttaaa
     9721 acaaaaagta gcaaatttgc aataaaatgt aattacaaac tcttgcgtat tcagtaaata
     9781 tactttatat ttgcagtgag tttttttcat agtattttag atctaaggtt aacaaagtct
     9841 ttgcagagag ggaatcgaga gactgtttca ctggaaagca acaaaaaagc cgcatccact
     9901 tttattatag ggagtgcggc ttttttgtgg gtttgaacga acataaagaa agcccgttgc
     9961 cattgacgac gggcttttcc atatacatat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgagtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acgacgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccgc
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaaccg gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat tgaaacggcg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt accttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtggccacc acaagattct gcgcggtcta
    10981 acgcatcgtg tgccatcaat gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagctg ttcgcttcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaagcc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacggtggat agaatcgaca gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 caggcaggtc agtgctaaag cgcggaacct ggatctggtc agacagatag ttctggatcg
    11341 tgtaaggcaa tacaaagtaa ccatcagcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc atggtcagag aagttggctt caccaattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaaccact tccttaccca gacggttgat agcgtcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac atcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatcctttc ccttttttgt tccggcctgc aatgccttcg
    11821 catcttccag cttcttcgga acccagatgc gaccatcgtt acgcagtgat tcagacatca
    11881 aagtcagttt agactggaag tcacctttca ccggcacaca agtcgggtgg atctgcacca
    11941 tacaaggatt agcaaagtaa gcccctttct tgtagcactg ccatgcagca gaaccgttag
    12001 acgccatcgc gttagtagac aagaagaatg tatttacata accacctgtc gcaacaacga
    12061 ctgcgtgagc ggcaaaacgt tcgatcttac cggtaatcaa attacgggca ataataccgc
    12121 gagcacgtcc gtcaaccttc acaacatcca gcatttcatg gcgtgtgtac atcttcacct
    12181 ttcccaaacc aatctgacgg ctcaatgcag agtaagcacc caacagcagc tgctgtccgg
    12241 tctgaccacg ggcatagaac gtacgggata cctgagcacc accgaatgaa cggttatcca
    12301 acagaccacc atattcgcga gcgaatggta caccctgtgc tacgcactgg tcgataatag
    12361 agtttgacac ttcagccaga cgatagacgt ttgcttcgcg ggcacggtag tcaccacctt
    12421 tgattgtatc gtagaacaga cgataaaccg agtcaccatc attctgataa ttctttgccg
    12481 cattgatacc gccctgtgca gcgatagagt gtgcacgacg gggagagtcc tgaatacaga
    12541 aattcaatac attgaatccc atttcagcca gagaggcagc agcagaagca cccgccagac
    12601 cagtacctac tacaattatg tccaaacgac gtttgtttgc gggattcacc aatttctggt
    12661 gatttttata atttgtccac ttctcagcca acgggccttg aggaatttta gaatctattt
    12721 gagtcataat gttttatttt caaattgaaa aaataatatc cgaaattaag cacctacacc
    12781 gttcaggtag aagataactg tgataacagc gaataagcca caaataatag tggcaaccca
    12841 tttagagata cattcccaac ggcttaacca aacggtattg ttccagccaa ttgtgtgaat
    12901 cgcagaccag aaaccgtgag tcaggtgaaa ccacagagca acgaaccaga tcagatacaa
    12961 caccgtattc acgacattgc cctggaagta gaaattgata aacgctgcac catcctgcgg
    13021 atgaatgtca ccatgaatac ctgccagttc ggcaaacatc atgttgtacc agaactgagt
    13081 aaagtgcaga accatgaaca ggataacgat cacacccaaa acaaacatgt tctgagaagc
    13141 ccattcaaca cctttcggac gagcgttgat ggcataacgg tcgttaccgc gagccttacg
    13201 attctgcaga gtcaagataa tagcatacac gaagtgcacg actacacctg cagccaacac
    13261 caatgtaccg agcaaagcat accagttaga acccagcaaa ccgcaaatca cgttatacgc
    13321 ttcaccagaa aatactgccg caatgttcat acataagtgg aacaccaaga acagaatgag
    13381 aaaaagacct gatatactca ttatcagctt cttcccgata gaagaattaa gtaaccacat
    13441 aagataataa tttaagttat ttaattgtat ttagaaattt cctccaatct atggttatta
    13501 tcgtgcaaag gtatgctaaa tccccatatc acgcaaacga ttaaagaaat atttcatcaa
    13561 ttagaacgct gcttgctggc tggttttatt tgcatcagat atcacaaacg gattgtgcga
    13621 aacgaaaaaa tttcgttttt ttgtagccga tacaggcaag gtcttgccgg ataactgatt
    13681 attatttaat tgtcatatta tgaaaactgc tattttttct attggtgttt ttttgatttc
    13741 tctgttctta ggctcttgtc agccttccga aacatcctgt tccgtcgtcg acacggggaa
    13801 aaccttagac tataagatag gagataaact gttgttctct tacaactata ccacagttta
    13861 cccagcctct ggcgttgact cggtctataa acgcagcggt ttcatccatc ctttgaagac
    13921 attgggaggc gaagtgatga ccaattgttc tcccgccgac cattaccatc atttcggttt
    13981 gtggtatgcc tggacgaaaa ccacgttcga aggaaacgag atcgacttct ggaatctcca
    14041 caaaaaacaa ggaacagttc gcttccgcaa cttcgaacac gtatccgaca acggttttgt
    14101 tgcgacactg gaccatgtgg tctaccccga ttctcccgca gaaaaagtag caatgaacga
    14161 acgcctggag atcaacatcg ggacaacatc cttaccaggt tattacatcg actatcatac
    14221 cactatccgc ctcgccagcc ccagcccgat caccatggaa gcttaccgtt atggcggcat
    14281 atgcatccgt acgcgcgaag actggaacga tcagacagcc gaaatgctca cctcggaagg
    14341 cctttcccgc gacgaagctg acggttcgag agcccgttgg tgctactacc aagggaaagc
    14401 cggaaacgaa aaggcctgta tcctaatcgt tgcctcccct tccaacctga actatcctga
    14461 gcctttacgc gtatgggaca aaactgtcaa caagcctgcc ggtgacgtca tgtggaattt
    14521 ctcaccgacc aagcagaagg cattcacctt ggaacccggt aaagaactga gcctgtctta
    14581 ccgcatttat gtattggaca agaacatcaa cgctactacg gcagaagtgc tgtccgattt
    14641 cgaacgtgat tgaatttcta ctaaaacaaa ctgacaattt gcagggcaag gtaaacaaga
    14701 aaaggaaaaa gggcttgttc tcctatatca tcaaagacaa ggctctttta tgtaaataca
    14761 gctacaaatc aatgaaaaac acgtaataaa acttacccaa cacccccatg tatccgcccc
    14821 cgacacccgg atctataaga gcgtaagatc cgggtgtcgg gggcggatac atgggggtgt
    14881 tgataaaatt gtctccctac ttttacctta aaatgcttgg agtttattca tttaaaacag
    14941 atagatgagc gattgtctcg tcctgaaata ggttgacttc ataaaagtca acaaagatga
    15001 aaaaaga
//
