LOCUS       c00099_gnlPro..        10057 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMKAEKNI_99.
ACCESSION   c00099_gnlPro..
VERSION     c00099_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:46:24
            Original ID  :: gnl|Prokka|OMKAEKNI_99
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10057
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10057
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5901:10056]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5902..10056
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10057
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10057
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2..1555
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_1"
                     /sec_met_domain="PLDc_2 (E-value: 1.5e-24, bitscore: 75.9,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTVQSCLLLIIHLIFGRFFVVAMAIILQVLWLCVVLWQLSYKFTY
                     VNLLVRVIAIIVVLVIVNKWTNPANKLSWTFLILLSPIFGLMVYFLFGRSGLTKHTRER
                     MDAVNRQVEALFQRDSAVEKGLEKESRSAYLQSSYIDKWAGFPLYQNTQTKYYSCGEEM
                     FPDMLEALRGAKHFIFLEYFIIEEGYMFNTILDILEEKAKAGVDVRFIYDDVGSINSIS
                     FGYYKKLQERGIPCVTFNPFKPLISVVMNNRDHRKIFVVDGYIGFTGGINLADEYINKV
                     KRFGYWKDTGVRIEGEAVWSLTAMFLEMWNYINRSTEDYSRFLPSVYREKEFTSDGFVQ
                     PYGDSPLDNENVGENIYLNIINRAKNYVYIFTPYLIIDHEMLICLSNAAKSGVDVRIVT
                     PGVPDKKAVYLLTQSYYEPLLKNGVKIFQYTPGFIHAKCFVCDDEIATVGSVNLDYRSL
                     FLHFECGVFMYRSKAVMQVKEDCLRTFEESEEMDVSFCRRRRLPVRMVQSLMRLFAPLL
                     "
     CDS             complement(1650..2867)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_2"
                     /sec_met_domain="Peptidase_S11 (E-value: 3.1e-77, bitscore:
                     248.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKFMVSILLGLNLLVQGTVLPASSCFIPNVTVPLSPAAQTDTAPA
                     ADLNISAPSAILMEAFTGAVVYEKNPHEARHPASVTKIMTLLLIFDALSSKQISLDDTV
                     TVSEYAASMGGSQVFLEPGETQTVETMIKCISVASANDACVAMAEHVAGSESEFVRMMN
                     ERAKGLGMNDTNFVNCCGLDADGHMTSANDIALMSRELITKYPKIHDYCTIWMENITHT
                     TAKGSSEFGLTNTNKLIKHYQYATGLKTGFTNTAMYCISATAKKDDMELIAVIMGAPDI
                     KSRSADATTLLNYGFGKCRIYCDSHEDKLDDLPVEKGLADSVGIIYQRPFQYMTTDGSD
                     LTGITKSIELPENVTAPVKKGNTAGKAVYSLNGTPIGSVNIVYADTVDAADYKDYFCRT
                     LLYFVP"
     CDS             3000..3749
                     /locus_tag="ctg99_3"
                     /transl_table=11
                     /translation="MELTVKLQVFEGPLDLLLHLLEKNKVNIYDIPIVEITNQYMEYIA
                     EMRRQDLNVMSEFLVMAATLLDIKSKMLLPAKESEDEEEEDPRAELVQQLLEYKMYKCM
                     AYELRDRQIDAEKVWFKAPTIPPEVLAYEEPVNVNELMSGVTLARLNDIFQSIIKKQAD
                     KIDPVRSKFGRIEKEEVSLSDKMTYVEEYSLHHGHFSFRSLLEAQSGKMEVVVTFLAIL
                     ELMKMGKIVVSQEYTFDDIKIESKIAA"
     CDS             3816..4385
                     /locus_tag="ctg99_4"
                     /transl_table=11
                     /translation="MEEKKYEAIVEAILFTMGESVELERIAKTLELDTERTKKIIEHLM
                     QRYEDDGVGVKIMELDGSYQMCTKGEMYEYLVKIAKQPKKHVLTDVLLETLSIIAYKQP
                     ITKAEIEKIRGVSCDHAVNKLVEYNLVCELGRLDAPGRPLLFGTTEEFLRSFGVQSIDE
                     LPVLSPVQVEEFKQEAEAEMHMKLDI"
     CDS             4480..5724
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 5.8e-51, bitscore:
                     162.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWKKLLAWILVTVILTGYGIQIVEAFDQKENVRMEEVIEKPDQNS
                     LYAKAAVLMDADSGRILYEKNGHQAMANASTTKILTCIIALENCDLDSEVTVSTLAASQ
                     PKVHLGMREGQKFYLKDLLYGLMLESYNDCAVAIAEHIAGTTGDFAKLMNDKAEEIGCE
                     DSYFITPNGLDAKNENGFHHTTAADLSLIMRYCIKTSEMAEQFLTITREGQYQFSDIDG
                     KNSYTCCNHNAFLQMMDGALSGKTGFTGNAGYCYVGALKRDDRTFIVALLACGWPNNKT
                     YKWADTKKLMQYGISRFRKISLDEIELDAGEYAPVQVVDGQGTKIGEEVTTELEVAPVK
                     ENVELLIEKDQEVHIEYQLSRKLYASVTEGDFIGEITYLLGDEVLAKRVVTVKNTVKRI
                     DFCWCVKKTAELFPM"
     CDS             5902..7335
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_6"
                     /sec_met_domain="CT_Vparvula (E-value: 1.2e-125, bitscore:
                     409.3, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSNDSLAMQRITKLVDENSFMEIGSLVTARNTDFNLADTDTPS
                     DGVITGHGLVDGNLVFVYSQNAAVLNGTIGEMHAKKIAAVYDMAMKMGAPVIGFIDCAG
                     MRLQESVDALNGFGEIYAKEVAASGVVPQISAIFGSCGGGLAVVPALSDFAFMESKGKM
                     FINSPNAIEGNRIEKCDTSSAEFQSEKNGCIDAVGTEDEIIAEIRELVSVLPLNNEGDV
                     YTSECQDDLNRACENMAAMKGDPRYLLSEISDGHVFFETKKNYAKDMVTGFIQLNGMTV
                     GAVANCSEVYDEEGKKAEEFSGALTARGCNKAAEFVNFCDAFEIPVLSLTNVKGYAATV
                     CAEKGLAKALARMTMAFADATCPKVNLITGNAIGSAYVTMNSKAIGADFTYAWEDAKIG
                     MMDGELAAKIMYADASADELAAKAKEYDALQSSVMTAARRGYVDLILDPADTRKYLVDA
                     FELLYTKCAGVPDKKHGTK"
     CDS             7348..8088
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_7"
                     /sec_met_domain="OAD_gamma (E-value: 4.6e-28, bitscore:
                     87.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKLSLMLCLCFMVLAMTACGTDPKSVDYFGMSYSDIQDNMEQT
                     VSALVSFSDEDIQSGAEYYDSNGMDAFAHLLTSWGETVSDLGSYQGLGDLTVTKAQKTV
                     TADQVLHFSDRDVVVSYVYEYNYETEAPELTDASADLVYSLGEKMGKAGMNTLMGMGTV
                     FVVLILISLIISCFKVIPYLQNKKANAGAKKDVADPVVEQIEQREETSQLTDDLELVAV
                     ISAAIAAAEGTSADGFVVRSIHRR"
     CDS             8154..8525
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 57.7; E-value:
                     2.6e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_8"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.1e-19, bitscore:
                     57.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGNVYDVTVEENGAVSAPAAAPRRAAAPAPAAAPKAA
                     APAGGAGNVKIEAGAAGKVFKIESSVGASVKKGDTILVLEIMKMETPVVATEDGTVASI
                     NVSVGDMVEAGALLATLNN"
     CDS             8542..9690
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_9"
                     /sec_met_domain="OAD_beta (E-value: 1.2e-158, bitscore:
                     517.0, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFTETMGNLLHQTAFFNLTWGNFVMILVACIFLYLAIAKGFEP
                     LLLVPIAFGMLLVNIYPDIFAAPEQMSNGVGGLFHYFYTLDEWSILPSLIFLGVGAMTD
                     FGPLIANPISFLLGAAAQFGIFGAYFLAILMGFNDKAAAAVSIIGGADGPTSIFLAGKL
                     GQSGLMGPIAVAAYSYMALVPIIQPPIMKLFTTKKERAIKMQNLRPVSKLEKILFPIVV
                     TVVVCLILPTTAPLVGMLMLGNLFRECGVVRQLSETASNALMYIVVILLGTSVGASTSA
                     EAFLNATTLKIVALGLIAFMFGTAAGVLFGKLLCFITKGKINPLIGSAGVSAVPMAARV
                     SQKVGAEEDPTNFLLMHAMGPNVAGVIGTAVAAGVFMAIFGI"
     CDS             9736..10056
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_10"
                     /sec_met_domain="HMGL-like (E-value: 7.6e-15, bitscore:
                     44.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVVKKPLKITETVLRDAHQSLIATRMTTEQMLPIVDKMDKVGY
                     YAVECWGGATFDASLRFLKEDPWDRLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFV"
ORIGIN
        1 cctaactgtg cagtcgtgtc ttttgttaat tatacatctc atatttggaa gattttttgt
       61 ggttgccatg gcaatcattt tacaggtgtt atggctgtgt gtcgtattgt ggcagctcag
      121 ttacaagttt acgtatgtca atttgcttgt gcgtgtgata gcaatcattg ttgtgcttgt
      181 aatcgtcaat aaatggacaa atccggcgaa taaactctcg tggacgtttt taatcttatt
      241 gtcgccgatt tttggactta tggtatattt cttatttgga agatccggtc tgaccaaaca
      301 tacaagagag agaatggatg ctgtcaaccg tcaggtggaa gcattgtttc agagagatag
      361 cgcagtggag aaaggcttag aaaaagaaag ccggtcagca tatctgcagt catcttatat
      421 tgataaatgg gcgggatttc cattatatca gaacacgcag acaaaatatt acagctgcgg
      481 ggaagaaatg ttcccggata tgttagaggc actgcgcggt gcaaaacatt ttatattcct
      541 cgagtatttt atcattgaag aaggatatat gttcaatacg atccttgata ttcttgagga
      601 aaaggcaaag gccggagtgg atgtgcgctt tatctatgat gatgtcggca gcatcaattc
      661 tatttctttt ggatattata aaaagctgca ggagagaggg attccctgtg tgacattcaa
      721 tccgtttaaa ccactgatct ctgtggtgat gaacaaccgc gatcaccgta aaatttttgt
      781 ggtggatggg tatattggat ttacaggcgg tatcaatctt gccgatgaat atatcaataa
      841 agtcaaaagg tttggatact ggaaggatac cggagtgcgg attgagggag aggcagtctg
      901 gagccttacg gcaatgtttc tggaaatgtg gaattatatc aaccgttcca cggaagatta
      961 cagcagattc ctgccgtctg tttacaggga gaaagaattt acctccgatg gctttgtaca
     1021 gccgtatggt gacagtccgc tcgataatga aaacgtcgga gaaaatattt atctgaatat
     1081 cataaaccgt gcgaaaaact atgtgtatat ttttacacca tatctgatca tcgatcacga
     1141 aatgctgatc tgtctctcaa atgcagcaaa gagcggtgtg gatgtaagga tcgtgacacc
     1201 gggtgtgccg gataaaaagg cagtatatct tttaacacag tcttattatg aaccgctttt
     1261 aaagaatggt gtgaagattt ttcagtatac accgggattt atccatgcaa aatgttttgt
     1321 ctgtgacgat gagatcgcga cggtcggcag tgtaaacctt gactaccgga gtctgttttt
     1381 acactttgaa tgtggtgtat ttatgtaccg gtctaaggca gtcatgcagg taaaggaaga
     1441 ctgcctcagg acatttgaag agtcggagga gatggatgtt tcattctgcc gcagacgaag
     1501 acttccggta cgtatggttc agagcctgat gcgtctgttt gcaccgttgt tataatatga
     1561 gaacaaatgt tccgcaccat cagatcagtg atatgtaata acagaatgtt tcatgacatc
     1621 aaatcagtga tacaccggac gctgtatttt taaggaacaa aatataacag ggtgcggcaa
     1681 aaataatctt tataatctgc agcatcgact gtatccgcat atacaatatt gacactgccg
     1741 atcggcgttc catttagaga atagaccgcc ttcccggcag tgtttccttt ttttactggt
     1801 gctgtcacat tttccggcag ttcgatgctt ttggtaatgc cggtaagatc acttccgtct
     1861 gttgtcatgt attgaaaagg tctttggtaa atgatgccta cagaatccgc aaggcctttt
     1921 tcaaccggga gatcgtctaa cttatcttcg tggctgtcac agtaaatcct gcatttccca
     1981 aacccataat tcaaaagagt cgtggcatcc gcagagcgtg acttgatatc aggagccccc
     2041 atgatgacgg cgatcagttc catatcatct tttttggcgg ttgcggaaat acagtacatg
     2101 gcagtgttgg taaatccggt ttttaagccg gtggcatact ggtaatgttt gatcagctta
     2161 ttggtgttcg tcagaccgaa ctccgaggaa ccttttgcgg tagtgtgggt gatattttcc
     2221 atccagattg tgcagtaatc atggattttc gggtattttg tgatcagttc gcgcgacatc
     2281 agtgcaatgt cattggcgct ggtcatatgt ccgtcggcat ctaaaccaca gcagttgacg
     2341 aaattggtgt cattcatacc gagtcctttt gcgcgttcgt tcatcatgcg gacaaattct
     2401 gattcggaac cggcaacatg ttctgccatg gcaacacagg cgtcattggc gctcgcaaca
     2461 ctgatacatt tgatcatcgt ttcgactgtc tgggtttcac ccggttctaa aaacacctga
     2521 gaaccgccca tgcttgctgc atattcggag acggtcaccg tgtcatctaa ggaaatctgt
     2581 ttggatgaga gtgcatcaaa aatcagaagc agcgtcataa tcttggtgac acttgccgga
     2641 tgccttgcct cgtggggatt tttttcgtag acgacggcac cggtgaaagc ctccatcaaa
     2701 atggcgcttg gtgcggagat atttaagtct gcagcaggtg cagtatctgt ctgggcagca
     2761 ggagacaggg gaacggttac attcggaatg aaacaggaag atgcaggaag tactgtgccc
     2821 tgcacaagga gattgagacc gagcagaatg gaaaccatga atttcaagaa tatgccctcc
     2881 gtagggttct gttataattt attttagata cgaaggatgt acattatgca taaaaatctt
     2941 gaattttgcg ggaatccacg gtaaaatcaa tatttgtgga atgagagggt atgacataga
     3001 tggaattaac tgtaaaactt caggtgtttg aggggccgtt agatctgctt ttacatctgt
     3061 tagaaaaaaa taaagtcaat atatatgata ttccaatcgt ggagatcaca aaccagtata
     3121 tggaatatat tgccgaaatg cgcagacagg acttaaatgt gatgagcgaa tttctcgtga
     3181 tggcggcgac actgcttgat atcaaatcaa aaatgctgct ccctgcaaaa gaaagcgagg
     3241 atgaggaaga agaagatccg agagcggaac ttgtgcagca gctgttggaa tataaaatgt
     3301 ataaatgtat ggcatatgaa ctcagggacc gtcagattga tgcggaaaaa gtatggttta
     3361 aagcaccgac aatcccgccc gaagttcttg catatgaaga accggttaat gtgaatgaac
     3421 tgatgtccgg ggtaacactt gcgaggctga atgatatttt tcagtccatc ataaagaaac
     3481 aggcggataa gatcgatccg gtccgttcga agtttggaag aatcgagaaa gaggaagtgt
     3541 cactttctga taagatgaca tatgtggaag aatacagtct gcatcacgga catttttcgt
     3601 ttcggagtct tttagaagca cagtccggga aaatggaagt ggttgtgaca tttctggcaa
     3661 tattagagct gatgaagatg ggaaagatcg ttgtttccca ggaatacacg tttgatgata
     3721 taaaaattga atcaaaaatt gcggcctagc tgtgtgacag cagaaatgaa atgggatctg
     3781 tgtggaattt ttacacaccg gaatagaggg ttggtatgga agaaaaaaaa tatgaggcaa
     3841 tcgttgaggc gattctgttt acaatgggag agtctgtgga attagagcgt atagcaaaaa
     3901 cactggaact tgatacagaa cggacaaaaa agatcataga acatctgatg cagcgctatg
     3961 aggatgatgg cgtcggcgtt aagatcatgg aactggacgg ttcttatcag atgtgtacga
     4021 agggcgaaat gtatgaatat ctggtgaaaa tcgcaaagca gccgaaaaag catgtgctta
     4081 ccgacgttct gcttgaaacc ctttcgatca ttgcctacaa gcagccgatt acaaaggcgg
     4141 aaattgaaaa gatcagaggt gtttcctgcg atcatgcggt aaacaagctg gtggagtaca
     4201 atctggtatg tgaacttgga aggctggatg cgccgggacg cccgctgctt tttggcacaa
     4261 cggaggaatt tttaaggagt tttggcgttc agtcaatcga tgaacttccc gtgttaagtc
     4321 cggtccaggt agaagaattc aaacaggaag cggaagcgga aatgcatatg aaactggata
     4381 tctgatctgg tttcgtatgc ttttttttca caaaaaatga gcattttttg cgtattatat
     4441 acataaggat tgatgaaatg cttttttgga gtctggtgta tgtggaaaaa actgctggca
     4501 tggatccttg tcactgtgat cttaacagga tatgggatac agatcgtgga ggcttttgat
     4561 caaaaagaaa atgtgcggat ggaggaagtg atagaaaagc cggatcaaaa ttccctgtat
     4621 gcaaaagcag ctgtgcttat ggatgcggat tccgggcgta tcctgtatga aaaaaacggg
     4681 caccaggcga tggcgaatgc cagtacgacc aaaatactga catgtatcat tgcactggaa
     4741 aactgcgacc tggacagcga agtgaccgtg agtacgcttg cagcgtcaca gccgaaagtt
     4801 catctgggta tgcgggaggg gcagaagttt tatctgaaag atctgctgta cggactgatg
     4861 ttggaatctt ataatgactg cgctgtggcg attgcagaac acattgcagg cacgacgggt
     4921 gattttgcaa aacttatgaa cgataaagca gaggagatcg gctgtgagga cagttatttt
     4981 atcacaccga acggactgga tgccaaaaat gaaaatggct ttcatcacac aacagcggca
     5041 gatctttctt tgatcatgcg gtactgcatc aaaacatcag aaatggcaga gcaatttctt
     5101 acaatcacaa gggaaggaca gtatcagttt tctgatatag atggtaaaaa cagttacacc
     5161 tgctgtaatc ataatgcatt tttgcagatg atggacgggg cattgtcagg caagaccggt
     5221 tttaccggta atgcgggata ttgttatgtc ggggcattaa aacgtgatga cagaactttt
     5281 atcgttgcac tgcttgcctg cgggtggccg aataataaaa catataagtg ggcagataca
     5341 aaaaaactta tgcagtatgg aatttcccgg ttccggaaaa taagtctgga tgagattgaa
     5401 ctggacgcag gggaatatgc tccggtacag gtggtggacg gacagggcac aaagatcggc
     5461 gaagaggtaa cgacagaact tgaagttgcg ccggtgaaag aaaatgtgga actattgatc
     5521 gaaaaagacc aggaagtaca catagagtat caattatccc ggaaacttta tgcatcggta
     5581 acggaaggag attttatcgg tgagataaca taccttctgg gagatgaggt tctggcaaaa
     5641 cgtgtggtca cagtaaagaa tacggtaaaa agaatcgatt tttgctggtg tgtaaaaaaa
     5701 acagcagaat tatttccaat gtaaaagtcc cagattcctt gtatgcaaaa aaaaactgtc
     5761 aaaaaattaa caattctctt gaaaatttgt cactgaccat ctataattta tcctagcgga
     5821 atttgttata tttttacatt attcactatg taccatgtca aaagatgtgg taacaaactt
     5881 tatagatgga gggcaaaaag gatgaatagt agtaatgata gcttggcaat gcagcgtatt
     5941 accaagttag tcgatgagaa cagtttcatg gaaatcggtt ctctcgtaac cgcaagaaat
     6001 acagacttta atcttgcaga cacagataca ccgtccgatg gtgtaattac cggacatggt
     6061 ctggtggatg gcaatctggt atttgtatac agccagaatg cagctgtatt aaacggtact
     6121 atcggagaga tgcatgcaaa gaagattgca gccgtatatg acatggcaat gaaaatggga
     6181 gcaccggtga tcggatttat cgattgcgcc ggaatgcgtt tacaggaatc tgtggatgcg
     6241 ttaaacggat ttggtgagat ctacgcaaag gaggttgcag catccggcgt tgttccgcag
     6301 atttccgcta ttttcggaag ctgtggcggt ggacttgcag tagttcctgc attatctgat
     6361 ttcgcattta tggagagcaa aggaaaaatg ttcatcaatt ccccgaatgc gatcgagggt
     6421 aaccgtattg aaaaatgcga tacttcttcc gcagagttcc agagtgagaa aaacggttgt
     6481 atcgatgctg ttggaacaga ggatgagatc attgcagaga tccgcgagtt agtaagcgtc
     6541 cttcctttaa ataatgaagg agatgtatac acatctgagt gtcaggatga tttaaaccgt
     6601 gcatgtgaga acatggcagc catgaaaggc gatccaagat atttattaag tgagatctca
     6661 gacggacatg tattctttga aacaaagaaa aactatgcaa aagatatggt aaccggattt
     6721 atccagttaa acggaatgac agtcggcgct gttgcaaact gctcagaagt ttacgatgaa
     6781 gagggcaaaa aagcagagga gttctccgga gctctgacag caagaggatg caacaaggca
     6841 gcagagttcg ttaacttctg tgatgcgttc gagatcccgg tattgtcttt aacaaacgta
     6901 aaaggttatg cagctactgt ctgtgcagaa aaaggacttg caaaagcact tgcacgcatg
     6961 acaatggcat tcgctgatgc aacctgcccg aaagtaaacc tgatcaccgg aaatgcaatc
     7021 ggaagcgctt atgtgacaat gaactccaaa gcaatcggag cagactttac atatgcatgg
     7081 gaagatgcaa agatcggtat gatggatggc gagcttgcag caaagatcat gtacgcagat
     7141 gcatctgcag atgaactcgc agcaaaagca aaagaatatg atgcattaca gtcaagtgtt
     7201 atgactgcag caagacgtgg ttatgtagat cttattttag atccggcaga caccagaaaa
     7261 taccttgtag atgcatttga attattatac acaaaatgtg caggtgtacc ggacaagaaa
     7321 catggaacaa aatagaaagg tgaagttatg aagaaaaaat tatctcttat gctttgtctt
     7381 tgctttatgg ttctggcaat gacagcatgt ggaacggatc ctaagagcgt tgattatttt
     7441 ggtatgagtt attctgatat ccaggataac atggagcaga cagtatctgc gcttgtttcg
     7501 ttttcagatg aagatataca gagtggtgca gaatattatg actcaaacgg aatggatgca
     7561 tttgcccact tactgacatc ctggggtgaa acagtttcag atctgggttc ctatcaggga
     7621 cttggagatc ttactgtgac aaaagcacag aagactgtga ctgcagacca ggttttacat
     7681 ttctcagaca gagatgtagt tgtttcttat gtatatgaat acaattacga gacagaagca
     7741 ccggaactta cagatgcaag tgcagatctt gtgtattcac ttggcgagaa aatgggaaaa
     7801 gccggtatga atacattgat gggaatggga accgtatttg tagttcttat cctgatcagt
     7861 ctgatcatca gctgctttaa agtgattccg tatttacaga acaaaaaagc aaatgctggt
     7921 gcgaagaaag atgtggcaga tccggttgta gaacagatcg agcagcgtga ggagacatcc
     7981 cagcttactg atgatttaga actggttgca gttatttctg cagcaatcgc agcggcagaa
     8041 ggaacatcag cagatggatt cgtagtacgt tctatccata gaagataggc gaagcagaca
     8101 agttataata aatatatgtc gtaaaaaagt aatgatcaca ggaggatgat tcaatgaaaa
     8161 gctatacaat taccgtaaat ggaaatgttt atgatgttac tgtagaagag aatggtgctg
     8221 taagtgcacc ggcagcagca ccgagacgtg cagcagctcc ggctccggca gcagctccga
     8281 aggcagcagc accggcaggt ggcgcaggta acgtaaagat cgaagcaggt gcagcaggaa
     8341 aagtatttaa gatcgagtct tctgttggcg catctgtaaa gaaaggtgac acaatcttag
     8401 ttcttgaaat catgaaaatg gagacaccgg ttgttgctac cgaagatggt actgtagcaa
     8461 gcatcaacgt aagtgttggt gacatggtag aagcaggtgc attactggca actttaaaca
     8521 actaatttta ggaggataac aatgagttat tttactgaga caatgggcaa cctccttcat
     8581 cagactgcct tttttaacct gacatgggga aatttcgtaa tgatcttagt tgcatgtatt
     8641 ttcctgtatc tggcgattgc aaaagggttt gaaccgttgt tactcgttcc gatcgcattt
     8701 ggtatgcttc tggtaaacat ttatccggat atctttgcag ctccggagca gatgagtaac
     8761 ggtgtcggtg gtttattcca ttatttttat accttagatg aatggtcaat cctgccatcc
     8821 cttattttcc ttggcgttgg tgcgatgacc gattttggac ctctgatcgc aaacccgatc
     8881 agcttccttt taggagcagc agcacagttt ggtattttcg gcgcatattt ccttgcaatc
     8941 ctgatgggat tcaatgataa agcagcagca gccgtttcta tcatcggtgg tgcagatggt
     9001 cctacttcca ttttccttgc tggaaaactt ggacagtccg gccttatggg accgatcgct
     9061 gtagcagcat attcttacat ggcactggtg ccgatcattc agccgccaat tatgaagtta
     9121 tttacaacga aaaaagaacg tgcgatcaag atgcagaact tacgtccggt atccaaactt
     9181 gagaaaatct tattcccaat cgtggtaacc gttgttgtat gtctgatcct tccgacaaca
     9241 gccccgctcg ttggtatgtt aatgcttggt aacctgttcc gtgagtgtgg tgtggttcgt
     9301 cagttatctg agacagcatc taatgcattg atgtatatcg tagttatctt acttggtaca
     9361 tctgttggtg catccacaag tgcagaggct ttcttaaatg caacaacttt aaagatcgtt
     9421 gcacttggac tgattgcatt tatgtttggt acagcagccg gagtattgtt cggtaaatta
     9481 ctttgcttca ttacaaaagg caagatcaac ccactcatcg gttctgccgg tgtatccgca
     9541 gttcctatgg ctgcgcgtgt atcacagaaa gttggtgcag aggaagatcc tacgaacttt
     9601 ttacttatgc atgcaatggg accaaacgtt gccggtgtta tcggtacagc agtagcagcc
     9661 ggtgtattca tggcaatctt tggaatttaa tcagacggca gaacaaaaac aggttcgctg
     9721 tataaggagg aaaaaatggc tgaagttgtt aaaaaacctt taaaaataac agagacagta
     9781 ctgcgtgatg cacatcagtc tctgatcgca acaagaatga caacagagca gatgcttcca
     9841 atcgtagata agatggacaa ggttggatac tatgctgttg agtgctgggg aggcgctact
     9901 ttcgatgcat cccttcgttt cttaaaagag gatccatggg atcgtcttcg taaattaaga
     9961 gatggtttta aaaatacgaa attacagatg ttattccgtg gacagaatat cttaggatac
    10021 cgtccatatg ctgatgatgt agtagagtat ttcgtac
//
