LOCUS       c00095_gnlPro..        12033 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOPIIBCM_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:24:45
            Original ID  :: gnl|Prokka|DOPIIBCM_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12033
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12033
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[152:3108]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      153..3108
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12033
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12033
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             153..2381
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_1"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-47, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTNPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2383..3108
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-31, bitscore:
                     99.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDIRLLGESLGKYRQIQRVEILPYHRLGVHKYEVMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(3177..5381)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 87; E-value: 2.2e-27)"
                     /gene_kind="other"
                     /locus_tag="ctg95_3"
                     /sec_met_domain="Fn3-like (E-value: 2.9e-28, bitscore:
                     87.0, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 2.9e-75, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 5.4e-53,
                     bitscore: 169.1, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRSKVVTLYDALVRKGLEVNYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALQQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKDAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNAGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(5412..7874)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg95_4"
                     /sec_met_domain="Fn3-like (E-value: 4.4e-26, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 4.6e-57, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 2.9e-51,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQAEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(8051..9367)
                     /locus_tag="ctg95_5"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEAVGIGQQAE
                     EPVVEDTDHETTMQAEEPERTREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTG
                     GFSLANEGEANVMSGYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREK
                     KIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIP
                     VRANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRV
                     GLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(9380..9844)
                     /locus_tag="ctg95_6"
                     /transl_table=11
                     /translation="MLSVCLRYAGDRETAQDLMHDGFLKLFDSFDKFTWRGEGSLRAWM
                     ERVMVNTVLQYLRKNDVMNQSSALENAPEAYEEPEGSSIDVIPQKVLMQFISELPAGYR
                     TVFNLYIFEEKSHKEIARLLGINEKSSASQLTRAKATLAAKVREWMKRND"
     CDS             10114..10818
                     /locus_tag="ctg95_7"
                     /transl_table=11
                     /translation="MKKLRMTLAASMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
     CDS             10999..12033
                     /locus_tag="ctg95_8"
                     /transl_table=11
                     /translation="MKYILGTVIAILCSFTCTDTLYGKSPATDVDDILIINTYTEANPW
                     SNDFITSIVNMASQNSHIGVYTAHMKMLTLDEENKLETFKESLFKSYKNPKLIVLIGCG
                     SFIMCDELNRQWPDIPMILCGERDYTGPKETMIREHALPRTERIPISDLQKKYNLTLMQ
                     SSVYLNENLQLMKQLIPKMDKVMYIGDETYICQQNDYDLSEIIREKYPELDYQFLSAKD
                     IRTDSLFNILNHVNPHTTGVIFSSWLYKSSPHDNIMRSNSHRVISTAPIPLFSLRAIGI
                     EEEGGIVGGYIYNKEKYNARLLETIHKILDGTPARNIPLYYPDDGAPVFNYKSLLQRDL
                     NPKLC"
ORIGIN
        1 tactcccccg gacattcact acctaataat agttatttta tgctgttcaa cataaaaaga
       61 gaagtatctc ttataaaatt acggaattta ttcagtattt ttgtgcgctc taaaggataa
      121 cattatctaa cctactaaca aaaacaaatt ttatggaatt gaacaaaacc tttaccaatg
      181 ggctttggaa taaagaaatc aatgtcagtg atttcgtcag taaaaacatc gcaccctata
      241 ccggggatgc atctttcttg cagggaccta ccgaacgtac caaacgtatc tgggacatct
      301 gtctgaaggc tctcgaagaa gaaaggaaca acaatggcgt ccgttcactg gacaatacca
      361 ccgtatctac catcacttct cataaagccg ggtatattga taaggacaat gaacttattg
      421 tcggtttgca gactgatgaa ctgttgaaac gatccatcaa acctttcgga ggcatcaacg
      481 tggtagcaaa agcatgccgt gaaaacggag tggaagtgga cgataaagta aaagacatct
      541 tcacccatta ccgcaaaaca cataacgacg gcgtattcga tgtatatacc gaagaaatcc
      601 gttccttccg ctcactggga ttccttaccg gattgcccga caactatgcc cgcggacgta
      661 tcatcggcga ctaccgccga ttggctctct acggcatcga ccgtctgatt gaagccaagc
      721 aggaggactt gcgcaacctc accggcccga tgaccgaagc acgcatccgt ctacgcgaag
      781 aagtggcgga acaaatcaaa gctttgaagg acatcaaggt tatgggcgaa tattacggac
      841 tcgacctcag ccatccggct acatcagctc aagaggccgt gcaatgggta tacatggcat
      901 atcttgctgc catcaaagag caagacggtg ctgccatgtc attgggtaac gtatcttcgt
      961 tcctcgatat attcattgaa tacgatctgg ctcacggaaa aatcaatgag acgtttgcgc
     1021 aagaactgat agaccagttc gtcatcaagc tgcgcatggt acgccatctg cgtatgcagt
     1081 cgtacaatga tatctttgcc ggtgacccga cttgggtgac cgaagccatc ggaggacgct
     1141 tcaatgacgg acgcgtgaaa gtcaccaaga cttctttccg cttcttgcag acgctataca
     1201 acctcggtcc ttctccggaa ccaaacttga ccgtactgtg gagtcccgaa ctgccggaag
     1261 gcttcaagga tttctgcgcc aaagtttccg tagataccag ctccatccag tacgaaaacg
     1321 acaacctgat gcgcgaagtg cgcaactgcg acgattacgg cattgcctgc tgtgtatcct
     1381 accaagccat cggcaagcaa atccagttct tcggcgcacg tgccaacctt gccaaggccc
     1441 tgctgcttgc catcaacggt ggccgttgcg aaaacaccgg aactgtcatg gtgaaaggta
     1501 ttcccgtatt gaccggcgag acactgaagt ttgaggaagt tatggccaac tacaagaagg
     1561 tactgactga aatagcccgt gtctacaacg aggccatgaa tatcatccac tacatgcatg
     1621 ataagtatta ttatgagaag gcccagatgg cattcatcga taccaaccca cgcatcaatc
     1681 tggcatacgg tgttgccggc ctttccatcg ccatagactc actgtccgcc atcaaatatg
     1741 ccaaagtcac tgcacgccgc aacgaaatcg gcctgaccga aggtttcgac actgaaggct
     1801 cattcccctg cttcggcaat aatgacgacc gtgtggacca cctgggagta gacctcgttt
     1861 actatttcag cgaagaactg aaaaagctgc ctgtctacaa gaatgcccgt cccacccttt
     1921 ccttgctgac tatcacctcc aacgtgatgt acggcaagaa gaccggtgcc actccggacg
     1981 gacgcgccaa aggtgttgcc tttgctccgg gtgccaaccc aatgcacgga cgtgacaaga
     2041 acggtgccat cgcttccttg agctccgtag ccaaattgcg ctaccgcgac tcgcaggacg
     2101 gcatcagcaa tacgttctcc attgttccta aatcactggg cccgacaccg gaagaacgtg
     2161 tagagaacct ggtaaccatg atggacggct acttcaccaa aggtgcccac catttgaacg
     2221 taaacgtact gaaccgcgaa atgctggaag atgccatgga acatcctgaa aagtatccgc
     2281 aactcaccat ccgcgtttcc ggctatgccg tgaacttcgt gaagttgagc cgcgagcatc
     2341 agttggaagt catcagccgt tcattccacg aaagaatgta atatgataaa tgtacactcc
     2401 tacgaaagta tgggaacatt cgacgggccg ggtctccggc tcgtcgtttt cctgcaagga
     2461 tgtccgttcc gttgtctgta ttgtgccaat ccggatacga ttgatgtaaa aggaggcact
     2521 cccaccactc cggaagagat tctgcaaatg gctatcagcc aaaaggcatt cttcgggaag
     2581 aaaggaggta ttactttctc cggcggtgag cctaccctgc aagcagaagc gctgattcct
     2641 cttttcaagg agctgaaggc gaacggcatc catatctgtc tggacagtaa cggaggcatc
     2701 tggaatgaaa aggtggaaga gctctttagc ctgactgacc tcgtgctgct ggacatcaag
     2761 caattcaatc ccgaacgcca ccgtacgctg acgggacgaa gcaacgaaca gacactccgc
     2821 accgctgcct ggctcgaaga acatgaacac cccttctggc tgcgttatgt actggttccc
     2881 ggttacagcg attcggaaga agacatccgc ctgctgggtg aaagtctcgg caaataccgg
     2941 cagatacaac gggtggaaat acttccttac caccgtctgg gcgttcacaa atacgaagtc
     3001 atgggatggg attacaaatt gaaagaagtg aaggaaaata ctccggaaca actggaacgg
     3061 gcagaaaaac tgttcaaaga gtatttcacg aatgtgataa ccaactaaaa cagaaaagca
     3121 aggctgtccg gatatgattc cagacagcct tgcttttcat ttataggaca agaatcctat
     3181 tctttcaagt tataggtaat ctgctgtaca tcatcactac tgccacccac cataaagacg
     3241 aaatcaccag gttctaccat ataattcatc tcattgtcat agaatcccag tgcatcgtca
     3301 gttatctgaa aagctacagt tttgctttca cccgcattca gatgaatttt cctgaagccc
     3361 ttcaactcct ttatcgggcg cgtaacagac gctaccttat cctgcacata caactggact
     3421 acttcctctc ctgcacactt accggtatta gtcactttta ccgacacctc cgtatggacg
     3481 cctgcatcct tgcccggcag cagtttcaaa tcagaatatc caaaatccgt atacgaaagc
     3541 ccatatccga aaggataggc aggctcagtg gaagcatcga tataggatgc cttataagtc
     3601 tgttgcaatg cggtaggacg accggtactc ttattctggt aataaatggg aatctgccct
     3661 acgtgtgcag gaaatgtcat gggcaattta gccgaaggat tatactctcc ccacaacaca
     3721 ttgcatatgg cattgccggc ctcactcccc agccaccaag tacacagtac cgcatcagca
     3781 tgttccctta tctcattgaa gattaccgga cgcccacaca tgacaagagc aatgacaggt
     3841 tttccagtct ttgccagttc cgacaccagc ttctgctgcc cctcgggtat ggctatattc
     3901 actttggaag ccttctcgcc actctgaccg aatctctcgc ctaccgccac aacaatgaca
     3961 tccgaagcct cagcagcctg caatgcttcc tgcagtccgg tcaattgatt gctcttcata
     4021 tcatagcctt cagcatagtt cacctccagt cctttccgga ccagtgcatc atacaaggtc
     4081 accactttgc tccggtccgt agtggcggcc caagcgcctg ccatatcgta ttgggatttt
     4141 gagagtcctc ctatcaaggc tatcttcctc gtctgtgccg tcaacggaag cacagattcc
     4201 ctattctcca gcaatacaac ggaacgctcg gccatacgga gcgaagcatt acggacttcg
     4261 ggcgcattga gtattctggc cgctctttcc ggattacagt agcgaaaagg gtcctcaaac
     4321 aatcccaact catatttctt ctccaatata cgccgtactg catcatcaag cacactctcc
     4381 tttactttcc cttcttgaac aagctccttc agataagtca agtagcaggt acttaccatc
     4441 tccatgtcca gaccagcatt cagcgctttg gctgcggcat ctttcttgtc aacagcataa
     4501 cggtggttca ccaattcctc taccgaatta taatcggaca caacaaatcc cttaaatccc
     4561 cactgctctc tcaatagccg gttgagcaag aaatcattgg cagtacaagg aatattatta
     4621 aaatcattga aagcactcat cacggtagct gctcctacct ttatggccgc cttataggga
     4681 ggcatataaa aattggcaaa gtggcccatt gacatatcca cactattata ctcctttcct
     4741 gctatcggtg caccatatcc ggcaaaatgt ttcatacatg ccatgacagt cgtcgtgtct
     4801 gccaaatcgt ctccttgcaa gcctctgaca cgcgcctccg ctacccgaga accataataa
     4861 gggtcctcac cggccccttc catgacgcgt ccccaacgtg cgtcccacga aatatccacc
     4921 atcggggcaa aaacccagtt caaaccatcg gcggcacttt ccaaagcatt gtagcgtgca
     4981 gcttcctcaa tcatggccaa atcgaaactt gcagcctcgg caagcggaag cggaaatccg
     5041 gtacgatagc cgtggataac atccagtccg aaaattaaag gaatgcgcaa acgcgattgc
     5101 aaagcaagct cttgataacg gcgtatatcc tttactccta tcacattcag catagagcct
     5161 attctgcctt gccggacata ctcttcttta ggaatatttc caccgtcggg tccggtaaaa
     5221 ttccctcggt aggtgcattg tgcaagctgg cctatctttt catccagcgt catctgcttc
     5281 atcaagcttg agatgaattt ctccttctcc gtagtttgtg ccgaggtaaa ggtgttacca
     5341 agtccccaca gacaaaccat cagtattatt atctttttca tactgccatt cttgttttga
     5401 tatttatttt atcataaaac aacagttgcc ttcaatggta aatcagctga agaaggacct
     5461 gccagaatct caaaagtccc cttttccact acaaaccgat gtgattccac atcatagtag
     5521 gcaaaggctt cctcatccag caatatccga acgcgcttgg tttcaccctt cttcaagtaa
     5581 accttatcgt agcctttcaa ctccttcaat ggacgcggaa cagaacattc cacatcccgc
     5641 acatatacct gagccgcttc cgcagcatcc atctttccgg tattcttgat gtcaaagctt
     5701 accgtaaccc ggcttccccc cgtcttctca acactcagat tactatattc aaaactactg
     5761 tatgacagtc catacccgaa aggataaagc ggctgctttc cgttccggtc atatccccta
     5821 taacctacga aaacaccttc ggcatactgc acccgtttat gaggtacatt gcgattgtca
     5881 taataattac catataccgg attatcttcc catttttcct cgatgctgac tggtagtttg
     5941 ccacttggcg aaagcttgcc cgtaatgatt tcggcaaggg cctttccacc ctcctgcccc
     6001 ggataccatg ccatcaaaat agcttgtaca ctctgccccc aattgcggaa atctattcca
     6061 cctccggcat tcaccaccac agccacatta tcatgaagtg aagccacttt attaatgaga
     6121 tattcctgcc cgtatgacaa tgcaaacgga cggtcgaacc cttcaccttc tgtactgctg
     6181 ttgaacccgg cacatacaat aacattcctg gcatgcttca gtgaagaggc caaacgctcc
     6241 tcatccatca ttcctgcctg gaaactgaca gtcgcctcac ccacattatc aaaatattca
     6301 atacgcaacc ggtatatctc ccctgcactg acctgcataa atgcactgcg ggtactgaat
     6361 gaatggttcc cccaatctcc ggtaatcagc ttatcgttta caaacagacg gtatccgtca
     6421 tcgccagcca gctggaactt gacagttcca tccttgtcag ccttgtaaac tcccgtccaa
     6481 cgggcagaaa actgatctac cggcatgccg tcgaacggtg caccgtattt ccaggcatgg
     6541 tctatggcag gctctatggc agcttgaaag agttctccgg taagattacg agtattataa
     6601 tattcgccct taaaaccgtt ttgcgtaaaa ctgccatccg tataaatctg ttgggacata
     6661 tccttataaa gaatgctgtc agacagcagt tctatctgtc tgccgccctt caactgaacc
     6721 ataccgtcat agagcgacac taccgaataa ggagtgacaa atccgcttcc tcctcctgtg
     6781 ggaataatat cggcattagg cccgattacc aatgttctac cgttccggta aggcaacgta
     6841 ccgttgtcat ttttcaataa cactactcct tccctcgcca agtcaagtgc aatttcctta
     6901 gactgtgcat tgtctttatc gatagattta tcttctctcg gagtatcaag tgctccaaaa
     6961 gcaatcaatg tctggagtat atgccggact ttggcgtcaa tggtctcttc cttcacgata
     7021 ccattctcta ttgccggaat aagaatctcc ctggtcatga atttaccgac gggcatttcc
     7081 aaatccaacc ctccattagc ggctcccaca ccggaatata cagatgtcca gtcagacatc
     7141 aggatacctt taaatcccca ctgcttgcgt aatacatcaa tgttcagcca gctgttttcg
     7201 gtggcatgca ccccgttcag cggattatag ctatccatga ccgctcctac tcctgcttcc
     7261 tgcacagctt ttcggaacgc gggaaaataa atttcctgca acgtgcgttc atccacatcc
     7321 gagctggcat gatgcctgct ccactcctgg ttattggctg caaaatgctt caccgtagcc
     7381 atgactccct cttcctgcac tcccaagata tattctttgg ctgtttcgcc cgtcagataa
     7441 gggtcttcac caaaatactc atagtttcgc ccgcatagag gagaacggta gatattgact
     7501 ccgggcccca acagaatact taccccacgg gcctttgcat cccgggccaa accatgtccc
     7561 agttctctag ccaacttacg gttccatgtc gaagccgaca agataccaca aggatacagg
     7621 gtactttgag tattgttacg tatgccttgc ggaccatcgg ccatcctgat ttcgggtatg
     7681 ccaagccggg gcacagcccg gatataaaaa gatttgggac cggaaatgta atcgattttt
     7741 tcttccagag tcatttgaga aaccaactcc ctggcacgct gctccgcctg gggagtaata
     7801 cacacttgtg cttttgccgt gattgcacaa caaagcaata gcccgcttaa ggctactttc
     7861 tttttaatct tcattttgtc tattttacta cgtgtttgtt atattgccgg gcatgtcccg
     7921 acctactttc tttcttctca atcaataaaa aaccgtgtcc cttcatccac caacgaagaa
     7981 acacggccga aagttattaa gaaaattctg aatctacaag aaagtggaca aaaacatgtc
     8041 tgtcctgcta tcaataagta agacgtatac cggcctgcaa cgtaaagtta cacgggttct
     8101 ccttgcgtat agtctgtatc gacgaaccgt catcaaagaa ataagatact cccggttcca
     8161 catacaggcc caccctattg cttatgttat actgggcacc gacagcaccc atgacagaaa
     8221 gctgtaccgg tttcacagtc tcactctcag taccaatctt gccatacaca catttttcaa
     8281 tggcaccccc cgccgaaacg tacatcgtaa agttctttgc atccacaaag ttccagttgg
     8341 cccgtaccgg aatgccaata taatgcagct tctggcttat cttttccgag ctgccctcat
     8401 accttacgtc agaagcaaga taggtatacg tcagcccgct ttccacagag aaacccttcg
     8461 ccaagttttt ccgcaccgaa acaccgaaac tgagcggttg tttatggtct atatccgcaa
     8521 ttttcttttc gcgtctttgc agatagggca taccatcctt aaaaaccagt tcctgcccgt
     8581 cgggaatagt aacaatacca ttggccgtag aggataaatc tacgttaccg ccataaatag
     8641 gacttccagg catgtagccc gacatgacat tcgcttcccc ttcattcgcc aatgaaaaac
     8701 ctcccgtatt tcctacggac aagccaaccg cccatccttt agcatcccta ccagaactgt
     8761 ttttttccgg aagatgcagt ttgtcccggc ctgacggacg atagcggtct tcccttgttc
     8821 tctccggttc ctctgcctgc attgtagttt catggtccgt atcttccact accggttctt
     8881 ccgcctgctg cccaataccg acagcctcat ctgcagtttc aaccggcagc atttcctcct
     8941 gctgttcttc gccaaccgat attctgatat gttgtgcaac caaagggtga cttgcctcct
     9001 tattgggcgc cgatgcattt ccatgtgccc gataagcagg ctctatggaa ttagtccgta
     9061 tggcaggtac tgtctgttcc ggcaagacgt ccggagccac agccaaagcg ggcactgacg
     9121 tatgccgcat ttcattccct accggactct gcaacagcca cagactgacg gacgaaaccg
     9181 ccaccagcaa cacagctgcc gcggccaccg cccagcgacg gaaaggtatc atcctatgcg
     9241 gtccggttat cggagctccg gaaacggaca attccttctc caaccgctcc catccggcaa
     9301 ccggcagcgg ttcggaatag tcttccagct tgtcctttat ctttttcaac cacaattcat
     9361 cttccatacg ttccttcatt taatcatttc ttttcatcca ctcacgtact tttgccgcta
     9421 aagtcgcttt agcacgcgtc aactgcgagg cagaggattt ttcattaatt cccaatagtc
     9481 gagcaatctc cttatgggat ttctcttcaa aaatatataa gttgaatacg gtacgatagc
     9541 cggcaggcaa ttcactgata aactgcatca gtaccttttg aggaatgaca tctattgacg
     9601 aaccttccgg ttcctcataa gcttcgggtg cattctccaa ggccgatgac tgattcatca
     9661 catcattttt ccgcaaatac tgcaacaccg tattcaccat tacgcgttcc atccatgccc
     9721 gcagagaacc ctctccccgc caagtgaact tatcgaaaga atcaaaaagt ttcagaaaac
     9781 cgtcatgcat caggtcttgg gcagtctccc ggtcacctgc ataacggagg catacgctga
     9841 gcatgcgtcc cgcatagcgc tcatannnnn nnnnnnnnnn nggcaagatt gtctccttgc
     9901 ctacagcgtt ctgccaattc ctgttcttcc attctctctt ttaacacgtg ttcaccctat
     9961 aaatgcaatc ggcgcaaaaa tactgcatca ggcagagaag aaaatcatac tttcatttct
    10021 ttaacagtat actacgcagt atttagcttt tcaccgcatt ttctgaatac aaaaataagt
    10081 tttaaataga aaaagagcta aaacctacca cttatgaaga aactgagaat gacattggca
    10141 gcatccatgc ttttattcct gactgccatt gtattgcaat catgcctgga cgattgggat
    10201 gacaaatatg acactttgtt cgccgtaggt acggtaaagg tcatcgaagg aaaagactac
    10261 tatttctcac tggacgaagg cagtaaacta tatcccagtg acacaaccta tgttcacgac
    10321 tatgccgtaa tagacggcca gagggctttc atctacttcc gcgaactgga agagaaactt
    10381 ccaggctacg aatacaatgc ccaaataaag cacatcgaaa acattctgac caaagacatc
    10441 tactccatgc ctgccgaaaa ggcagacagt atcggagacg acaacatcaa cgccacggat
    10501 ttatggatta cgggcgagta tctgaacatc aaatatcaat tctaccacag caacaacgaa
    10561 gataagaagc acatgctgaa cctggtcatc aatgaagcat ccaccggcga aaacgacaaa
    10621 ccggattacg tcaatctcga attccgccac aatgcctaca atgacagcca gctcacgctg
    10681 ggcaccggac tggcctcctt caagctggac aatatagcgg aacaactgaa agagaaaaaa
    10741 gggctgaaca tccgtgtcaa aagtctatat gacggtgaac ggttcatgac catagacatt
    10801 aaaaaagaaa acaactaaat ctcctgaaaa cacatctttc aacatctcaa tgagaagcgg
    10861 agtgacattt caatatgttg ctccgcttta tttttccata tcccgcttaa attcatcttt
    10921 ttctttgtct atccaccggg aaacccctac atttgtaaga attttcacaa tagcaaacat
    10981 taaaacggtc caaaggatat gaaatacata ctgggaacag taattgcaat actctgctcg
    11041 ttcacctgca cagacaccct atatggaaaa tctcccgcaa cagacgtcga cgatattctg
    11101 ataatcaaca cttatacaga agccaatccc tggagtaatg atttcatcac ctccattgtg
    11161 aacatggcat cacagaacag ccacatcgga gtatacaccg cacacatgaa aatgctgaca
    11221 cttgacgagg aaaataaact ggagacattc aaagagagct tgttcaagag ttacaaaaac
    11281 cctaaactta tcgtgcttat cggatgcgga agtttcatca tgtgcgatga actgaaccgg
    11341 cagtggcccg atatccccat gatattatgt ggtgagaggg attataccgg tcctaaggaa
    11401 acaatgatac gcgagcacgc cctgccccgc acagagcgta ttcccatcag tgacctacag
    11461 aagaagtaca atctgacctt aatgcaatcc agtgtatacc tgaacgagaa cctgcaactc
    11521 atgaagcaac tcatccccaa aatggataag gtcatgtata taggggatga aacatacatc
    11581 tgccagcaga acgactatga cttgtccgag attatccgtg aaaagtatcc ggagttggat
    11641 taccagttcc ttagtgcgaa ggacatccga acggacagcc ttttcaatat actgaaccac
    11701 gtgaatcccc atactaccgg agtcatcttt tcatcctggc tgtacaagag ctctccccat
    11761 gacaatatca tgaggagtaa ttcccaccgg gtcatctcta ccgcccccat ccctttgttt
    11821 tcgctaaggg ccatcggtat tgaagaagaa ggggggattg taggcggcta catttacaac
    11881 aaagagaaat ataatgcccg gctactagaa accatccaca agatattgga tggtaccccg
    11941 gcacgcaaca tcccgttata ctatcccgac gacggagccc ccgtattcaa ctataaatcc
    12001 cttctgcagc gtgacctgaa tccgaagcta tgc
//
