LOCUS       c00054_gnlPro..        16552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBBHEFLD_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:02:33
            Original ID  :: gnl|Prokka|PBBHEFLD_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16552
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16552
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4954:7803]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4955..7803
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16552
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(753..1232)
                     /locus_tag="ctg54_1"
                     /transl_table=11
                     /translation="MLDIILIILGVLCLITGLMGCVLPFLPGPPVAYLGLVLLHFTDKA
                     QYSTTQLIVWLLIVIVIQILDYFTPMLGSKYSGGSKWGNWGCIIGTLVGLLFLPWGVIF
                     GPFLGAVIGELIGNKEFSQALKSGVGSLVGFMLGTLLKFVVCGYFCYQFIMGFIR"
     CDS             complement(1361..2803)
                     /locus_tag="ctg54_2"
                     /transl_table=11
                     /translation="MSLRYDAAFYVQVLDKYVATGECAEADNEPLYAYLLSVMNDPMIK
                     IQVLSDELCARIFYDAMSQFIRLNLEKQKYNMQKSQSEQQGMELVLEWSETKRKDGWQA
                     LLQEVADKHEGNGFDKAFYQGQFGNEGKYADEEVWERMVDDWKEAFQRDLQEQKEKEIE
                     QRKDDFERRLHANLRNIPGYIRQNNIEKDEFYQAWGLMSGMWNTVDFERIRKIVRIQKE
                     YPEVVKVANKMGRMADDEGQEQLHVAQGNVYKMEHSSKSDILGITVGNDLNALLPTELA
                     HCADDELEDLFVYKYVTRKLQTFRYKSEIMQPARRLEIKPATQKGPMIVCLDTSGSMVG
                     KPEKIAYSLLIKILEIADRQRRDCFLIAFSVSINPIDVRRERARLLEFFSTTSCGDTDA
                     TRMLQAIFRLLQSKKEYMNADVLWISDFKIPLSVPELTDKMLEYRKVDTHFYGLQLGIA
                     ENEWSPFFDRIYRIDYTPSRRY"
     CDS             complement(2793..4346)
                     /locus_tag="ctg54_3"
                     /transl_table=11
                     /translation="MEIKERIQLLLSEMNRGVYEKEAEIGLSLLAALAGESILLLGPPG
                     VAKSMVARRLKRAFVDARAFEYLMSRFSTPDEIFGPVSISRLKESDKYERAVDGYLPTA
                     DVVFLDEIWKAGPAIQNTLLTVINEKLFRNGDTELKLPLKLLVAASNELPTQGEGLEAL
                     WDRFLIRIISTCVKQEEAFYQMLLDDGDEEEQEACRWQISDEEYAGWQKEIRQIKVSAE
                     VLSCITEIRKNLEKVEIQGSEVHRNVYVSDRRWKNIVKLLKASAFIHGRKEVCLTDLLP
                     VYHCLWNEPEECADIRQIVVRALFVPYVKEIAAINLSLKSDLKVSRVREALEKARQKGD
                     RRDDDLMIIDHFYYQIENHGTGNTYIFIVDYKNLKEYSPKDVPATGVMYADPLNPKRTI
                     IRTFSDATKMKEQGAERVTLYRDEKNLYINGVRFPMRRLKRGEQQQLWLGNMTLTDRDY
                     ETELETAHDRIEKLVKDLSENIFISEEDKKGVAQYVATLRKEIAWARVDVRKLRYGDES
                     "
     CDS             4639..4920
                     /locus_tag="ctg54_4"
                     /transl_table=11
                     /translation="MEQIDNLKELINQGDVDIAIKQLDQLLQDDSVEKDKDMLYYLRGN
                     AYRKKGDWKQALNNYQYAIDLNPDSPAVQARTMAIDILNFYHKDMYNQ"
     CDS             4955..5182
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_5"
                     /sec_met_domain="Fer4_7 (E-value: 4.2e-13, bitscore: 40.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 9.3e-09, bitscore: 25.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.4e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.8e-09, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCAMVCPDGCISVYKVKVE"
     CDS             5195..6277
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_6"
                     /sec_met_domain="PFOR_II (E-value: 3.2e-28, bitscore: 88.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.6e-49, bitscore: 157.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVLTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTDAEVIEQCPWAATGKAKGRKPNIITSLEL
                     KPEAMEINNIRFQAKYKQIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPSKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALEEKIIK"
     CDS             6288..6464
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILALAAIIVYFVVGKEDFKMFIYVCGAAIF
                     VKLMEFFIRFTNR"
     CDS             6477..7241
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-26, bitscore:
                     82.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLVAEVIE
                     EMGMEEKTVGVSPVGCAVFAYNYLDIDWQEAAHGRAPAVATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKSNKWMEEHMFPFYPLGDLKDKE"
     CDS             7261..7803
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_9"
                     /sec_met_domain="POR (E-value: 2.1e-36, bitscore: 115.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDTAIILNQPSLEKFESRVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLQLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIHEV"
     CDS             7924..9966
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MRRILLLYILFSVVGLSAIHAQLNPARQQIDENGRDQYGNQVDPA
                     MIPDKLDSANVEVQGLPPTLYMWRIKNQLGDRTMIPADTTYHHFQNTNLTEGITGHYNY
                     LANLGSPRLSRIFFERRYPEPTIFMESFSSFFIRPTEFNFTNSNVPYTNLTYHKAGNKQ
                     NGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTSYFNAALFGSYIGDRYQVQGI
                     YSNNYLKTNENGGITDDRYITAPEEMAEGRKEYESVNIPTVLNASANRNHDFYVFLTQR
                     YNLGFHRDIPQAENDTMPAKQEFVPVTSFIHTIQVERSRHNFRSDDNVENYYKQTLLDK
                     ENTFVRDSTVYIGVKNTIGIALLEGFNKYAKAGLTAFASHKLSKYSLMSLDPLKQDKYN
                     ETEIYIGGELTKKQGNFLHYHAIGEVGMAGKAIGQFDVKGDIDLNIPLWKDTVSVIARG
                     EISNKLAPFYMRHYHSKHFWWDDDMDKEFRTRIEGELSIANWGTRLRAGVENIKNYTYF
                     NQQALPEQKGGSLQVVSACFNQDFKVGIFHLDNEVIWQKSSDQAVLPLPELSLYHNFYM
                     QFKLAKKVLSVQLGADVRYFTKYDAPAYMPATQQFYLQPEEGKVEIGGYPIVNVYANLH
                     LKRTRFYVMMYHVNQGMSKPNYFLAPHYPINPRVLKFGLSWNFYD"
     CDS             9984..10823
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="MKTRPKLRLFRYLLPVVIVLALIFSVRYCGKQEKPLGHPRDYAAI
                     AKEGILHVATEYNSISFYVDSDTVSGFHYELIEAFARDKGLKTEITPVMSFDERLRGLS
                     DGRYDVIAYGILATSELKDSLLLTSPIILNKQVLVQRKANGENDSLYIRNQLDLAQKTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIEKYGSEQLISLVAHGDIDYAVCDESIARAVV
                     DSLPQVDINTAISFTQFYSWAVSKQSPALLDSLNTWLDKFQKEKEYQKIYRKYYGDK"
     CDS             11266..11787
                     /locus_tag="ctg54_12"
                     /transl_table=11
                     /translation="MELKQFKITVVPLRDKLLNYARRMTDDPSDAEDAVQEVMLKLWNL
                     RQKLDEYRSIEAVAMTMTHHLCMDMWRAKRPDTLSLDRVQAPTPSATPERLLEEKDEFR
                     LMREIIDSLPTLQRTIIRMKDIEEYETEEIAEITGCNAEAIRSNLSRARKKVREVYLQT
                     IQERKRRNKA"
     CDS             11784..12245
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MKDIETLLNKYFEGETTCEEERRLRRFFAEGLVPEHLEVYRPMFA
                     FFEAEQKELAEISGKGNAAEMPELAPFEKKTKTVRQYLTYSLSAAAAAILLLVGISGIY
                     RHLSPAPANYVIIDGKEYTDVHLIREQAMVAFRDVSLSEEEVFATLFDE"
     CDS             12266..12715
                     /locus_tag="ctg54_14"
                     /transl_table=11
                     /translation="MMNKIIRTTLITLLLTFAAHAAAQQGLQIATVFQKYGKQKGVTMV
                     ELSNEMLETYQMTLYKSLVFKDASDALPTILRCLEADKKKAKKVKEVVSNGQIKSGYYQ
                     LPQLKEDVNRFILFKTGKKDSATLIYIEGELDADDLITMLFMKKE"
     CDS             12740..13642
                     /locus_tag="ctg54_15"
                     /transl_table=11
                     /translation="MKKLLLLWLMIAPMSGMAQNESTPQDTTLYVNGRKIVIKEQGDKI
                     KVKLYESASGGDTITNAQIFEGVYLNGQSTESRTVLSALPFSKKNNKRNRFEPHAGGFY
                     IGYTRLSNDFLSFNPSNGADLNTSHSWEIGGNLFTGSHAFAPTYNWGITIGLGWGYRSM
                     RLDGNYAFREIDGVTEIYSGMEAEEPIEYSKSRLRYFYFRIPLSIEWQTRLNGKGPLFF
                     AVGPEAEIRHGFRSKAKVNGSKKTIDKGLNGRPLGINLLAQAGYADLGVYMRYSTYGLF
                     EKNKGPELYPFSFGVCWYW"
     CDS             13756..14742
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_16"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8e-28, bitscore:
                     88.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 7.8e-10,
                     bitscore: 29.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKMIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIRKWYDDAQELIDDPEVNAIYIATPPSSHATYAIMAMKAGKPAYIEKPMAVT
                     YEECTRINRISKETGVPCFVAYYRRYLPYFQKVKEMVENGSIGNVINVQVRFAQPPRDL
                     DYNRENLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDNGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTERGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             14882..15334
                     /locus_tag="ctg54_17"
                     /transl_table=11
                     /translation="MRKAIELSKENVANGGGPFGAVIATKEGEIIATGVNRVTSSCDPT
                     AHAEVSAIRAAAAKLGTFNLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNKTDAKNI
                     GFDDSFIYDELALKPADRKLPSEVLLHNEAITAFEAWMSKEDKVEY"
     CDS             15372..16175
                     /locus_tag="ctg54_18"
                     /transl_table=11
                     /translation="MKRKNFLILLAAGCLFSCQQQDELQETSKEATNFSISIDDALSDP
                     LTRTSNDLFPARNSITTGEVISMAASGQDYTPFIVGKDSRAWNEIGTATGTVTFYAHYP
                     ALTDEAATRSGGNKRYLKGGQEHLFGTAEAAPGSQNVSLKFKRMTVPVIILDENDRPYE
                     GEAKVELSLKNEGTQDLLNGTIEINENALSENIEVKKVSEGVTTNVLPQKINAGEEIGT
                     ITVGGVTQKISAVEDLDLKAGSTLSVRLSKKFGGGIIDGNVPLYR"
     CDS             complement(16322..16552)
                     /locus_tag="ctg54_19"
                     /transl_table=11
                     /translation="FCNEYEAFANWRRTGYPKLTPARNAASYPNNVTNGEIPRRFIYPT
                     SEITANPVNYNDAVKRLSGGDKMTSRVWWDK"
ORIGIN
        1 ccttcgggaa ggaggagtgg tcgaagaccg aggtggtagg agaaataatg tttgttcctt
       61 ttttattgaa aatgatagag taatgtattc acctaccacc tccccctatg ggtactcctc
      121 cttcccgaag gaggagattt aagatactat tgacttttta gtcagcccca ttcaagatac
      181 tattgactat catttaattc aaaacataca tagaaatgaa gtaaatgata atctacgtca
      241 tcactattgg tatcttatgc catgatttac cgctacttta cgcgtagact attaataaga
      301 aagtttctct tcattataga taaacttgca ttcagttaac aataaagtta ttttcggcct
      361 atttcaatct acaaatgaaa gcttcgtttt tataaatgca acttttgttt ttataaatac
      421 aagttctatt tttataaaca aaacttgcat ttatagatta taattgacag aagataagtt
      481 tatctactga ataacagaag tttaccatta ataaaccaac ttctatctat taatagctaa
      541 tcggttgaaa acgatgaaat ccgggtgaaa gatgaaagat caggtgaaag atgattttat
      601 gatctatcac cctctgaaac accgatggat aaaaagattg ggagatgctg gtgataggtg
      661 aaagatgatt ttgcgttttt ctttatatag ttgtaatcac aacagctaaa caacttctaa
      721 taaagtatag aacaccgatg atctgaaaat aatcaccgaa taaaccccat tatgaactgg
      781 tagcagaaat aaccgcaaac gacaaacttc agcaaagtgc ccaacataaa gccgactaat
      841 gaaccgactc ccgacttcag agcctgggaa aattctttat ttccgatcag ttcgccgatc
      901 actgccccta gaaaaggacc gaaaataact ccccaaggca agaaaagaag tccgacgaga
      961 gttccaataa tgcaacccca gtttccccat ttactgccac cactatattt actgccaagc
     1021 atcggagtaa aataatctaa gatctgtatg acaataacaa tcagtagcca aacgatcaac
     1081 tgcgtggtag aatattgtgc cttatctgta aaatgaagaa gaaccaatcc caaataagca
     1141 acgggaggac cgggtagaaa tggaaggaca catcccatca atccggtaat gaggcacaac
     1201 acacctagta taatcaaaat aatatccaac atagtttatt caaattaaaa ataataagta
     1261 cccttgcttt attagttcat actactttta tccaataaat aacaaagata cctattccgg
     1321 tggcaattta agcaaataaa ccgaatcctc caaaaaacaa tcagtaacgt cgggaaggag
     1381 tataatcaat tctataaata cggtcgaaga aaggactcca ttcattctcc gcaatcccaa
     1441 gttgcagacc gtagaaatgc gtatccactt ttctatattc cagcatcttg tcagtcagtt
     1501 ccggcacgga taaaggtatc ttaaaatcac tgatccataa cacatccgca ttcatatact
     1561 ccttttttga ttgaagcaac cggaagatag cttgcagcat tcgggtagca tccgtatctc
     1621 cacaagaggt ggtggagaaa aattcaagca gccgcgccct ctctctccgc acatcaatcg
     1681 gattgatgga tacagaaaag gcaatcagga aacagtcccg acgttgcctg tcagctattt
     1741 ccaatatttt aatcagcagc gaatatgcaa tcttttccgg tttcccgacc atgcttccgg
     1801 aagtgtccag acagactatc atcggtcctt tctgcgtagc aggctttatt tccagtcgcc
     1861 gtgccggttg catgatctcg gatttatagc ggaaggtctg aagttttcgg gtaacatatt
     1921 tatagacaaa caagtcttcc agctcatcat cggcacaatg cgccagttct gtaggaagca
     1981 atgcgttcag gtcattccct actgtgatac ccaaaatgtc acttttagaa gaatgctcca
     2041 tcttatatac attcccctgc gcgacatgta gctgctcctg tccttcatcg tcagccatac
     2101 gccccatctt attggcaacc ttgaccactt ccggatattc tttctgaatg cggacaattt
     2161 tgcgtatccg ctcaaaatcc accgtattcc acataccgct catcaagccc caagcctgat
     2221 agaactcgtc tttctctatg ttattttgcc ggatatatcc ggggatattc ctgagattgg
     2281 catgaagtct gcgttcgaaa tcatctttgc gctgttctat ctccttttcc ttttgctcct
     2341 gcaaatcccg ttggaaagcc tctttccagt cgtccaccat cctctcccag acttcctcat
     2401 ccgcatattt cccttcattg ccgaactgcc cctgataaaa tgccttgtcg aaaccattac
     2461 cctcatgttt gtcggcaacc tcctgtagta aagcctgcca cccgtctttc cgcttggtct
     2521 cggaccattc cagcacaagt tccattcctt gctgttccga ctggcttttc tgcatattgt
     2581 acttttgctt ttccagattc agacggataa actggctcat tgcatcgtaa aagattcggg
     2641 cacaaagttc atcactcagg acttgtatct ttatcatcgg atcgttcatg acggaaagca
     2701 ggtaagcgta cagcggttcg ttatccgcct ccgcacactc tccggtcgct acatacttat
     2761 ccagcacctg cacataaaat gcagcatcat atctaagact catcgccgta tctcagttta
     2821 cggacatcca cacgtgccca tgcaatctct ttacgaaggg tcgccacata ttgtgccacc
     2881 ccttttttat cttcttcgga aataaaaata ttctcagaca agtcttttac taatttctca
     2941 atccggtcat gggctgtctc caactccgtc tcataatccc ggtcggtgag agtcatattg
     3001 cccagccaca actgctgttg ctctcccctc ttcagccgac gcatcggaaa gcggacacca
     3061 ttgatataaa gattcttctc atccctgtaa agtgtcaccc tttcggcacc ttgttccttc
     3121 attttggtgg catccgaaaa agtacgtata atcgttcgct tcggattcag cggatcggca
     3181 tacatgactc ctgttgcagg aacatccttc ggactgtatt ctttcagatt cttataatcc
     3241 acaataaata tgtaggtatt tcccgtacca tgattctcta tctgatagta gaaatgatcg
     3301 atgatcatca aatcatcgtc cctgcggtca cctttctgac gggctttctc caatgcttca
     3361 cgcacgcggc tcactttcag gtccgacttt aatgataagt tgatagcggc tatctccttc
     3421 acataaggaa caaacagcgc acggacaacg atctgccgga tatccgcaca ctcttccggt
     3481 tcattccaca agcagtggta aacaggtaat aaatctgtca ggcagacttc cttccgacca
     3541 tgaatgaaag cagaagcttt cagcagcttc acgatattct tccagcgacg gtcgctcaca
     3601 tagacattcc gatgtacttc cgagccttga atctcgactt tctccaggtt cttacggatt
     3661 tctgtgatgc aggacaggac ttcggcagat accttgatct gccgtatctc tttctgccat
     3721 ccggcatatt cctcatccga aatctgccac cgacatgctt cctgttcttc ttcgtcacca
     3781 tcgtccagca acatttgata gaacgcttcc tcctgtttca cgcaagtgct gataatgcga
     3841 atcaagaaac ggtcccacaa ggcttccagt ccttcgccct gcgtaggcag ttcattactg
     3901 gcagccacca gcagcttcaa cggaagtttc agttccgtat ctccattccg aaacagcttt
     3961 tcattgatga ccgtcagcaa cgtattctga atagccggac cggctttcca tatttcatcc
     4021 agaaacacga catccgctgt aggcagatac ccgtccacag cacgctcgta tttatccgat
     4081 tccttcagac ggctgatgct caccggacca aagatctcat caggtgtgga gaaacgagac
     4141 atcaggtatt caaatgccct tgcatctaca aaagctctct tcaaccgacg ggccaccatc
     4201 gactttgcca ccccaggagg tcccagcaac aaaatacttt cgccagccaa agcagccagc
     4261 aaagacaaac cgatttcagc ctctttctca tatacccccc tgttcatttc ggacagcagc
     4321 aactgtatac gttcttttat ttccatatta ttctttgatt ctgcacataa ataaagatgt
     4381 tattcacctt accgcctatg cattgtttgc agataaacgg cttgcaaata tacggtttta
     4441 cctgtcatta acataaatac atcttctcta attctgtctt ttatactcaa gaattatctt
     4501 aaggcatatt taatattgat tatttattca cccaatatgc aataaaaaca aaaggaggta
     4561 aatttccttt ctcattttcc cccatttaca taaataaaaa ctatctttgc gattcagaat
     4621 cccgaaagac gaaagaaaat ggagcaaata gacaacctaa aagagcttat caatcaaggg
     4681 gatgtggaca tagcaatcaa gcaattggac caacttctcc aagacgattc tgtcgagaaa
     4741 gataaagata tgctctacta tttacgggga aatgcctacc gaaaaaaagg agattggaag
     4801 caggcgctga ataactacca gtatgctatc gatcttaatc ccgacagccc cgctgttcaa
     4861 gccagaacaa tggcgataga tatcctgaat ttctaccaca aagatatgta taatcaataa
     4921 ccgaattcaa agataacgta ataaaataga gattatggca aaaattaaag gagcaatcgt
     4981 agtcgacacg gagcgttgca aaggatgcaa cctatgtgta gtagcgtgtc cgctcgatgt
     5041 aatcgccctc aacaaagagg tgaatatgaa aggctataac tatgcctggc aagtaaaaga
     5101 agatacctgc aacggatgca gctcgtgtgc aatggtttgt cccgacggat gtatctcagt
     5161 gtataaagta aaagtagaat aaaagaaaaa gaatatggca gaagaagttg tattaatgaa
     5221 aggaaacgaa gccatcgccc acgcagctat ccgttgcggt gcggacggat acttcggata
     5281 tcctattact ccccaatcgg aagtactgga aacgcttgcc gaactgaaac cgtgggaaac
     5341 aaccggcatg gtagttctcc aggcagaaag tgaagtggca gctatcaata tggtatatgg
     5401 aggcgcaggt agtggaaaga tggtattgac ctcttcctca agtcccggcg tgagtctgaa
     5461 acaggaaggt atctcctaca tcgcaggtgc cgaacttcct tgtctgattg taaacgtaat
     5521 gcgcggcggc cccggattgg gaaccatcca gccgagtcag gcggactact tccagacagt
     5581 gaaaggaggc ggtcacggtg actacaggct gattgccctc gctccggcat ccgtacagga
     5641 aatggcggat ttcgtggcac tgggattcga gcttgctttc aaataccgta acccggctat
     5701 catccttgcc gacggtgtaa tcggacagat gatggaaaaa gtagttcttc ctgcacagaa
     5761 gccacgccgc accgatgcag aagttatcga acaatgtccg tgggctgcta ccggaaaagc
     5821 gaaaggtcgt aaaccgaata ttattacttc actcgaactg aagccggaag caatggaaat
     5881 caacaacatc cgtttccagg ctaaatacaa acagattgag gaaaacgaag tacgcttcga
     5941 agaaatcaac tgcgaagatg cagaatatct gatcatagct ttcggttcca tggcacgtat
     6001 cggtcagaaa gcaatggaac tcgcccgcga aaaaggaatc aaagtaggta ttcttcgccc
     6061 catcactttg tggccgttcc cgagcaaagc cattgccgct tacgctgaca aagtgaaagg
     6121 tatgctcgtt acagaattga atgccggaca gatgatcgaa gatgtccgcc tggctgtcaa
     6181 tggtaaagta aaagtagaac atttcggacg tctcggcggt attgttcccg atccggatga
     6241 aattgtaact gctctggaag aaaaaataat caaataacga aacgacgatg aatcccgata
     6301 aaataagaaa cgtattgaac atccttttca tgatattggc acttgccgct atcattgtct
     6361 actttgtagt aggaaaggaa gattttaaaa tgtttatcta cgtatgcggc gcggcaatct
     6421 ttgtcaagct gatggagttt tttatacggt tcaccaacag ataaggagaa gaagttatga
     6481 ctaaagaaga aataatcaaa cctgagaatc tggtttataa aaaaccgact ctgatgaatg
     6541 ataatgccat gcactactgc ccgggttgca gtcacggcgt ggtacacaag ctcgttgccg
     6601 aagtcattga ggaaatgggc atggaagaaa aaacggtggg agtctctccg gtaggatgcg
     6661 cagttttcgc ctacaactat ctggatatag actggcagga agccgctcac ggacgtgcac
     6721 ctgcagtagc tacggctatc aaacgcttat ggcccgaccg tctcgttttc acttatcagg
     6781 gtgacggtga cctggcctgt atcggtaccg ccgaaacaat ccacgcactg aaccgtggcg
     6841 aaaacattac tattatcttt atcaataacg ctatctacgg tatgaccggc ggacaaatgg
     6901 ctccgacgac tctggtaggc atgaagagtt ctacttgtcc ttacggacgt gatgtcgaac
     6961 tacacggcta tccattgaag ataaccgaga ttgccgccca actggaagga actgcttacg
     7021 ttacccgtca gtcggtacaa tcagtgcccg ccatccgcaa agccaagaaa gcaatacgca
     7081 aggcattcga aaattcgatg aacggcaaag gttccaatct ggtagaaatc gtatcaactt
     7141 gtagctccgg ctggaagatg actccggaaa aatcaaataa atggatggaa gaacatatgt
     7201 tcccattcta tccactgggt gatttaaaag ataaagaata acgcaaaagt caacagaaca
     7261 atgaaagaag aaataattat tgctggattc ggcggacaag gcgtattgtc catgggtaag
     7321 attctggctt attccggact gatggaagga aaagaagtga gctggatgcc ggcatacggt
     7381 cctgaacaac gaggcggaac agccaatgtg acagtgattg tcagcgatga caaaatctct
     7441 tcaccgatcc tgagtaaata tgatacggcg atcatactga accagccttc actggaaaag
     7501 tttgaaagca gagtaaagcc gggcggtatc ctgatctatg acggatatgg gattatcaac
     7561 cctcctaccc gcaaggatat caaagtatat cgcatcgacg caatggatgc tgccaacgaa
     7621 atgaataatg cgaaagcctt caatatgatc gtacttggcg gtttactgca actccgtcct
     7681 atcgtaactc tggaaaacgt catcaaagga ttgaagaaaa ctcttccgga acgccatcac
     7741 cacttgattc ctatgaacga ggaagcgatc aaaaaaggaa tggaattaat ccacgaagtt
     7801 taataaatta agagtttaaa attgagaatt gagaattatt tgctagataa tagcgcgatg
     7861 caacataatt ttcaattctc aattctcaat tctcaattta agtaagtatc tttgcctcca
     7921 attatgagac gaatcttact attatatata ttattctccg ttgtaggact gagtgctatc
     7981 catgcacagc tcaaccctgc ccgccagcaa atcgacgaga acggacgcga ccaatatggt
     8041 aatcaggtag accctgccat gattccggac aaactggata gtgccaatgt tgaagtacag
     8101 ggactgccgc ctacactata tatgtggcgt atcaagaacc aattaggcga ccggacaatg
     8161 attccggcag atacaactta ccatcacttt cagaatacga atcttacaga aggaatcacc
     8221 ggacattata attatctggc caatttaggt tcaccgcgtc tgtcgcgtat cttctttgag
     8281 cgccgttatc cggaaccaac catctttatg gagtctttct ccagcttttt cattcgcccg
     8341 acggaattta actttacgaa tagtaatgtt ccttatacta acctgaccta tcacaaggcc
     8401 ggaaataagc aaaatggaga agaacgtttc aaatcttatt tttcagtcaa tgtaaacaag
     8461 aagttggctt tcggctttaa tattgattat ctgtatggcc gaggctacta taataatcaa
     8521 aacacttctt attttaatgc cgcgcttttc ggtagttaca ttggcgaccg ctatcaggtg
     8581 cagggaatct atagcaacaa ctatctgaaa acgaatgaga acggtggtat cactgacgac
     8641 cgctacatta ccgcaccgga agaaatggca gaaggaagaa aagaatatga atctgtcaat
     8701 atccctaccg tactcaatgc cagtgccaac cgtaaccatg acttctatgt ctttctgaca
     8761 caacgctata atctgggatt ccaccgggat attccacagg cagaaaatga tacgatgcct
     8821 gccaaacagg aatttgttcc ggtcaccagc tttatacata ccattcaggt agaacgttcg
     8881 cgccataatt tccgttcgga tgataatgta gaaaactatt ataagcaaac tctccttgat
     8941 aaagagaata cattcgtcag agacagtact gtctatatcg gagtcaagaa taccataggt
     9001 attgctttgc tcgaaggctt caacaaatat gcaaaagccg gattgacagc ctttgcctca
     9061 cataagctga gcaaatattc attaatgagc ctagacccgc taaagcagga taaatacaat
     9121 gagacagaaa tctatatcgg tggcgaactg actaaaaaac agggaaactt tcttcattat
     9181 catgcaatcg gtgaagtggg aatggcagga aaggctatcg gacagtttga tgtcaaagga
     9241 gatatcgact taaatatccc tttatggaaa gataccgtca gtgtgattgc acgcggagaa
     9301 atcagtaata aacttgctcc attctacatg cgtcattacc actccaaaca tttttggtgg
     9361 gatgatgata tggataagga attccgcacc cgtatcgaag gcgagctgag catagctaat
     9421 tgggggaccc gcttaagagc cggtgttgaa aatataaaga actatactta tttcaaccag
     9481 caggcattac cggaacaaaa aggtggtagt ttgcaagtag tatcagcttg cttcaatcag
     9541 gatttcaaag tgggaatctt ccatctggac aatgaagtga tctggcagaa atccagtgat
     9601 caggctgtac ttccattgcc ggaactttcg ctgtatcata acttctatat gcagttcaaa
     9661 ctggcgaaaa aagtattgag tgtacaatta ggtgctgatg tacgttactt cactaaatat
     9721 gatgctccgg cctatatgcc tgctacacag cagttctacc tgcaaccgga agaaggtaaa
     9781 gtagagatag gcggttatcc gatagtgaat gtttatgcta acttacactt gaaacgtacc
     9841 cgtttctatg tgatgatgta tcacgtcaat cagggaatga gcaaacctaa ttacttccta
     9901 gcacctcatt accccattaa cccacgtgtg ctgaaattcg gactttcatg gaacttctat
     9961 gattaacaaa acctctatgg cttatgaaaa cgcgcccgaa attgagacta ttcagatatc
    10021 tgttgccggt agtcattgta ttggcactta tcttctctgt ccgctattgc ggtaaacaag
    10081 aaaaacctct ggggcatccg cgtgattacg cagccatcgc caaagaaggc atcctgcatg
    10141 tagccaccga atataattca atcagttttt atgtagacag tgacactgtc tccggattcc
    10201 attatgaact gatagaagcg ttcgcacgtg acaaggggct gaaaactgaa atcactcctg
    10261 tcatgagctt cgacgaacgg ctgagaggat taagcgacgg acgctacgat gtcatagcat
    10321 acggaatact ggcaaccagc gaactgaaag attctctgct tctcacctcc cccatcatac
    10381 tcaacaagca ggtgctggtg caacgaaaag cgaacgggga gaatgattca ctttatatcc
    10441 gaaaccaatt ggaccttgcc caaaagacac ttcatgtggt aaaaggctcg ccttctattc
    10501 tacgtattca gaatctggga aatgaaatcg gagatactat ttatataaag gaaatagaga
    10561 aatacggttc agagcagttg atttcgttag ttgctcatgg agatatcgat tatgccgtct
    10621 gtgatgaaag cattgcccgt gcagtggtag attcattgcc tcaggtagat atcaataccg
    10681 caatcagttt tactcaattc tactcatggg cagtcagcaa gcaatcaccc gcattgctcg
    10741 atagtttgaa tacatggctg gataaattcc aaaaagaaaa agagtatcaa aagatttacc
    10801 ggaaatacta tggtgataaa tagataaaaa ataatacgcc gaagacttga ctttcgcatt
    10861 tgaatgtcgt atctttgtca acgtaatcat aaagtagttt cagttaaact acacgtaaag
    10921 gagggaatca cagttccctc ctttcttttt gttacaatga atgaaaatca gcctttttcc
    10981 cagctttttg ctcattttac ccccgagctt agtccgtttt acctcgtttg ttaccatact
    11041 taacatagta tcttatgact aattagatgc tttgttatga ttaatcagat gctttgttat
    11101 ccataaaccg atgctttgtt ctcccaaaac agaagctctg tttccggaca gctcccaaga
    11161 gttaacaatc aataaagttg ctcttgacaa aaatttgctc tacttttgaa aaaaattccc
    11221 ttttcgatgt cacgttttta atccgccacc gtcttatcag tgtaaatgga actgaaacaa
    11281 tttaaaataa ccgttgtacc ccttcgagac aagctgctga actacgcccg aaggatgaca
    11341 gatgatcctt cggatgcgga agatgccgta caggaagtca tgctgaagct gtggaatctg
    11401 cgccagaagc tagacgagta cagaagtatc gaagccgtag ccatgaccat gacgcatcat
    11461 ctctgcatgg atatgtggcg tgccaaacga ccggacactc tatcactcga ccgtgtacag
    11521 gctcccaccc cttcggctac tccggagcga ctgctggaag agaaagatga gttcagattg
    11581 atgcgggaaa ttatcgactc cctgcctacg ctgcaacgaa cgattattcg catgaaagac
    11641 atcgaagagt acgagacgga agagattgcc gaaatcaccg gctgcaacgc agaagccatc
    11701 cgcagtaatc tgtcgagggc ccgcaagaaa gtaagggaag tctatttgca aacgatacaa
    11761 gaacgaaaaa ggaggaacaa agcatgaaag atatagaaac cttgctaaac aaatatttcg
    11821 aaggagaaac cacttgcgaa gaagaacgca gactacgacg tttctttgcc gaagggctcg
    11881 taccggaaca tctggaggta tatcgcccga tgttcgcttt cttcgaagcg gaacagaagg
    11941 aacttgcgga aatctccggt aaaggtaatg ccgccgagat gccggaactc gccccattcg
    12001 agaaaaagac aaaaacggtc agacagtatc tgacttacag tctcagtgct gccgctgccg
    12061 ccatcctgct actggtgggc atctccggta tctaccgtca tctatcccct gcaccggcca
    12121 actatgtgat cattgacggt aaggaatata cggacgttca tttaatccgt gaacaggcga
    12181 tggtcgcctt tcgtgacgtc agcctcagcg aggaggaagt attcgctact ttatttgatg
    12241 aataatataa aaacagcata taattatgat gaataaaatc attcgtacca cactaatcac
    12301 cctgttactt acattcgccg cccatgcggc cgcccaacag ggactacaga ttgccaccgt
    12361 cttccagaag tacggaaagc aaaaaggggt aactatggta gagctatcca atgaaatgct
    12421 ggaaacttac cagatgactc tttataaaag tcttgttttc aaggatgcca gcgatgcact
    12481 acctacgatt ctccgttgcc tggaagccga caagaagaaa gcaaagaagg tgaaagaagt
    12541 ggtttccaac gggcaaatca agtccggcta ttaccaactt ccccagctta aggaagatgt
    12601 gaaccgcttt atcctcttca aaaccggaaa gaaagattcg gctaccctta tctatattga
    12661 aggagaactg gatgccgacg acctgatcac catgttattc atgaagaaag aataaaaaaa
    12721 cagataaaga aatacgaata tgaaaaaact attattacta tggctcatga tagctccaat
    12781 gagcggcatg gcacaaaatg aaagtacacc gcaggataca acactttacg tcaacggacg
    12841 gaagatcgta atcaaggaac aaggcgacaa gattaaagtg aaactctacg aaagcgcatc
    12901 cggcggagat acgataacaa acgcgcaaat cttcgaagga gtctacctga acgggcagag
    12961 tacggaaagc cgtaccgtgc tgagcgctct ccccttctcg aagaaaaaca acaagagaaa
    13021 caggttcgag ccacatgccg gcggattcta catcggctac acccgactgt ccaatgactt
    13081 cctctcattc aatccgtcga acggtgccga cctcaacacc agtcattcat gggagatagg
    13141 cggcaatctg tttaccggtt cgcacgcctt tgcacctacc tataactggg ggatcaccat
    13201 cggactagga tggggatacc gcagtatgcg cctggacggc aattatgctt ttcgtgaaat
    13261 agacggagtg actgaaattt actccggcat ggaggcagaa gagcctatag agtacagcaa
    13321 aagccgtctg cgctatttct acttccgcat tccgctctct atcgaatggc aaacacggct
    13381 caacggcaaa ggtcctttgt tttttgctgt aggtcccgaa gccgaaatac gtcacggatt
    13441 cagatccaaa gccaaagtca atggatcgaa gaagacgatt gacaagggac tgaacgggcg
    13501 cccgctaggt atcaacttac ttgcacaagc cggttatgca gatttaggag tgtatatgcg
    13561 ttactccacc tacggcctct ttgagaagaa caaaggtccc gaactttatc cgttctcttt
    13621 cggtgtatgc tggtactggt aaagtaaata ctcagaccct tgcctatttc tgacagttaa
    13681 caatcaataa agttgttctt aataaaaaat agctttatct ttgggagttg ttaaaacaag
    13741 cacaataggt atattatgag tgaaaagatg attaaatggg gcttcatcgg ctgcggagaa
    13801 gtaaccaaaa ccaaaagtgg ccccgccttt caaaaggtag aacattctga agtagtagct
    13861 gtaatgagcc gcgacggcgc caaagcaaag gcttatgcaa aagaaagagg gatcagaaaa
    13921 tggtatgatg acgctcagga actgatagac gatccggaag taaatgccat ttatatcgcc
    13981 actcctcctt cttcacacgc tacatacgcc attatggcta tgaaagcagg caagcctgcc
    14041 tatattgaaa aaccaatggc tgtcacttat gaggagtgta cacgtatcaa ccgtatttct
    14101 aaggaaacgg gtgttccctg tttcgtcgca tattaccgcc gctatctccc ctactttcag
    14161 aaagtgaaag aaatggtaga gaacgggtct atcggtaatg tcatcaacgt acaagtccgc
    14221 tttgcacagc cgccacgtga tttggattac aaccgtgaaa atcttccttg gcgtgtacag
    14281 gctgatattg ccggtggcgg ttacttctat gaccttgccc cgcatcagat cgacttgctg
    14341 caagatatgt tcggctgcat cctcgaagcc agcggatata agagcaatcg tggagggctt
    14401 tatcctgccg aagatacgct gagcgcctgc ttccagttcg acaacggatt ggtcggcagt
    14461 ggttcatggt gctttgttgc ccatgattcc gcccgtgaag accgcatcga aattatcgga
    14521 gataaaggta tgatctgctt ctctgtcttt acgtacgagc cgattggtct gcacaccgaa
    14581 cgcggccggg aggaaatctg tatcggtaac cctgagcatg ttcaacaacc tcttattcag
    14641 gcagtagtag atcatctgct cggtaagtca gtctgctcat gcgacggaga aagtgctacc
    14701 ttgactaact gggtaatgga caaaatatta gggaagctct aagataaagc tccttcgttt
    14761 gtttcttaaa ataatttaat cactatattc tatcgttagt tttctttata tttgcgaaag
    14821 gtagcaataa aagcaaaact aacgatattt attttttata actatgacca aagaagaact
    14881 aatgaggaaa gcaatagagc tttcgaagga aaatgttgct aatggtggag gcccgttcgg
    14941 agctgtcatt gcaacaaaag aaggagaaat tatagctaca ggagtcaaca gagtaacctc
    15001 ttcatgtgat cccactgctc atgccgaagt tagcgccata cgtgccgcag ccgcgaaact
    15061 gggaacattc aacctcagcg gatacgaaat ctatacttca tgcgaacctt gcccgatgtg
    15121 tctgggtgcc atctattggg cacgactgga caaaatgtat tatgggaaca acaaaacaga
    15181 tgccaaaaac atcggtttcg acgattcctt tatttatgat gagctggctc taaaacctgc
    15241 cgacagaaaa cttccctcgg aagtattatt gcacaacgaa gccattacag ccttcgaagc
    15301 ctggatgtcc aaagaagaca aagtagaata ttagcatcta atctcactta aactcactaa
    15361 tacttagtaa aatgaaaaga aaaaactttt tgattcttct agccgcagga tgtttgttca
    15421 gttgtcagca acaggatgaa ctgcaagaaa caagtaaaga agcaaccaac ttctctatct
    15481 ctatcgacga cgctctctct gacccgctca cccgtaccag caatgatctg ttccctgcca
    15541 gaaatagcat cactacagga gaagttatct ccatggctgc ctccggtcag gactatactc
    15601 cgtttattgt tggcaaagac agccgcgcat ggaacgaaat aggaactgcc acaggcacag
    15661 taaccttcta cgcccactat cctgcattga cagacgaagc cgctaccaga tcaggcggta
    15721 acaaacgcta tttaaaagga ggtcaggagc acttgttcgg aacagcggaa gcagctccgg
    15781 gcagccagaa tgtatcactg aaattcaaac gaatgaccgt gccggttatt atacttgatg
    15841 agaacgatcg tccgtatgaa ggcgaagcta aagttgagct cagcctgaaa aacgaaggta
    15901 cgcaggattt attgaacggt accatagaaa tcaacgaaaa tgcgctgtca gagaatatcg
    15961 aagtaaagaa agtatccgaa ggcgttacta ccaatgttct cccgcaaaag atcaatgctg
    16021 gagaggaaat aggaacgatc actgtcggag gagtcactca gaagatcagt gcagtggaag
    16081 atcttgattt aaaagccgga agcacacttt ctgtcagatt atcaaaaaaa ttcggaggcg
    16141 gtattattga tggtaatgtt ccattgtaca gataagaaga ttgcacttaa agacaatctt
    16201 gcagattata taaatataaa gaacgggatt cgtatgaatc ccgttctttt atttagacct
    16261 aaaaactata taataagccg gtcagtcccc aagagccgac cgacttattt ataacacttt
    16321 attacttatc ccaccatacg cgtgatgtca tcttatcgcc tccgctaagt ctcttaacgg
    16381 catcattgta attaacagga ttagctgtta tttcacttgt cggataaatg aaacgacgag
    16441 gaatctctcc atttgtcaca ttgttaggat agctggctgc atttcgagcc ggggttaatt
    16501 ttggatatcc ggtacgacgc caatttgcaa aagcttcata ctcattacag aa
//
