LOCUS       c00089_gnlPro..         9888 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOJOFOOJ_89.
ACCESSION   c00089_gnlPro..
VERSION     c00089_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:08:18
            Original ID  :: gnl|Prokka|AOJOFOOJ_89
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9888
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9888
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[201:7358]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      202..7358
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9888
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9888
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             202..672
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.2e-26, bitscore:
                     80.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYCRPPPCIPYNHHTHMIQQIDHIGIAVKSLDATVPYYRDALGLG
                     EPHIEEVPTQKVRVAMFDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIAFKTNDIAG
                     NISQAKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGGCECGK"
     CDS             704..2269
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_2"
                     /sec_met_domain="CT_Vparvula (E-value: 9.2e-217, bitscore:
                     709.8, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDPKLIDDLNSRRKKVILSGGQEKIDKRHEKGEMTARDRMGYL
                     FEEGTFSEIGMHVRHNCHNFGMGKKEIPGDGVVSGFGLVDGRPVACAASDFLAQGGSLG
                     YMHAMKIADAQKYALKAGIPMVTVNDSGGARLQEGVAALSGYAQVFYNNVLASGVVPQI
                     SMILGPCAGGAAYSPALTDFIIMRNSGNAGMYITGPKVIEQVTYEKCTMDDIGSAAIHA
                     TVSGNVHFVADSDAHAMDILKRLLSFLPSNNTEEPPHKLDTPLDLSADEGMSDLIPGDN
                     RTPLDVQPIISRLVDNGDFLEVHKDFAKNVVVGFGRICGVVVGIIANQPNVKAGCLDID
                     SSDKAARFIRFCNAFNIPLVNLVDVPGFLPGKNQERGGIIRHGAKLIFAYSQATVPKVT
                     LIMRKAYGGAYIAMCCKDLGADAVFAWPGAEIAVMGAEGAVPVLYGRELKAVEDPAEKA
                     KRQGELLEEYREAFYNPYVAAGMGQITEVINPEETRAKIAFALRTLLNKKEVRPAKKHG
                     NIPL"
     CDS             2291..2743
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_3"
                     /sec_met_domain="OAD_gamma (E-value: 4.2e-10, bitscore:
                     29.7, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTTLAFAFAQGIANVMNNLNYQVVGIMVVMLCLGGMAVILTVS
                     GSIAAAIQNRAKAKTAAPVAVSAAAPAAAGKPGMTPEMLAILSAAVDSAMTELTPEMVA
                     VISAAVDAGLDGMSHRIVEIKQSPGSGYAAAGRAEIFASHRIRPSR"
     CDS             2816..3217
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 58.8; E-value:
                     1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-19, bitscore:
                     58.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRITVDGKVFDVSVELLDQVSSTTAAPAPAPVAAPAPAASAP
                     VAAPAPAPAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGAPVKAGDQILTLEAMKMNTII
                     YAPASGTLTAFCVNPGDTVQEGQALAKIG"
     CDS             3341..4984
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_5"
                     /sec_met_domain="OAD_beta (E-value: 2.7e-157, bitscore:
                     512.5, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVFSLSWQMVGMWGIAILLLYLGVAKQYEPLLMVPIAFGALIAN
                     IPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAPSKVPANLTTPESR
                     AQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSLTVDPNLKDFQNVT
                     EDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEPLVVSAAGKYVAVG
                     QHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLLAAPRTLLLGAAAQ
                     VGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAXXXKLAPHLLGAVAVAA
                     YTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTILLIPDASP
                     LIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQSETLLIIL
                     LGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVGQKYDPSN
                     YLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             5022..5801
                     /locus_tag="ctg89_6"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARTLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAADVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             5862..7358
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_7"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 5.6e-47,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4e-44, bitscore:
                     140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             7477..8178
                     /locus_tag="ctg89_8"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGAGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLAAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLATLSAILAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(8396..9259)
                     /locus_tag="ctg89_9"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFEYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPLR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(9269..9886)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_10"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.6e-49, bitscore:
                     158.4, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TESTPYRPHSPYSASKASSDHLVRAWHDTYGLPVLITNCSNNYGP
                     CQFPEKLIPVVILKALGGEPIPVYGKGENVRDWLYVGDHCEALLTVVSCGKPGETYNIG
                     GNNEKTNLELVELLCSHLDELRPRPDGRSYREQISFVQDRPGHDLRYAIDASKIRRELG
                     WTPRQDHSSGFRKTIQWYLDHEEWWRGILSGEYRLERLGTNG"
ORIGIN
        1 acggcatacg agatcgagta atgtgactgg attcagacgt gtgctcttcc gatctaataa
       61 cacggctaat ccactcttga acatgcccct accatacctc atcttccggg gcaatcaagc
      121 aggtgaaagg ggcggccacg aattcgccat ttttccgctt ttcgcttcac atcctaaaaa
      181 aatacgcttt aataactctt gatgtattgc aggcctcccc cctgcattcc ctataaccat
      241 cacacgcata tgattcagca aattgaccat atcggcatcg ccgtcaagag tcttgacgcc
      301 accgtcccct attaccgcga tgcgctcggg ctcggagagc cccacattga ggaagttccc
      361 actcaaaagg tccgcgtcgc catgtttgac gttgccggag tccacatcga actgctcgaa
      421 cccacctctc cggaaagcgc tatcgccaag gctattgaga aaaaagggga aggcatccac
      481 cacatcgctt tcaagaccaa tgacatcgcc ggaaatatct cccaggccaa ggaagcaggc
      541 cttaccgtgc tgaacgaccc gcccgtcccc ggcgctcaca acacgcaggt caccttcctg
      601 catcccaaat gcaccttcgg cgtcctgacc gaattctgcc agcaccccgg cggctgcgaa
      661 tgcggcaagt aacattctcc ctattcacca taccactaga ccaatggcta ttgatcccaa
      721 attgattgac gatctgaaca gccgccgcaa gaaagtcatc ctcagcggcg gtcaggaaaa
      781 gatcgacaag agacatgaaa agggcgaaat gacagcccgc gaccgcatgg ggtacctctt
      841 tgaggaaggc accttctcgg aaatcggcat gcatgtgcgc cacaactgcc acaacttcgg
      901 catgggtaag aaggaaatcc ccggcgacgg cgtcgtttcc ggtttcggcc tggtggacgg
      961 ccgcccggta gcctgcgcgg cctccgattt cctggcccag ggcggttccc tcggctacat
     1021 gcacgccatg aaaattgcgg atgcccagaa gtatgcgctg aaagccggca tcccgatggt
     1081 gaccgtgaac gactccggcg gcgcgcgcct ccaggaagga gtggcggccc tttccggata
     1141 cgcccaggtg ttttacaaca acgtgcttgc ctccggcgtg gttccgcaaa tctccatgat
     1201 cctgggcccc tgcgcgggcg gcgcggccta ctcccccgcc ctgacggact tcatcatcat
     1261 gcgcaattct ggcaacgcgg gcatgtacat caccggtccc aaagtgattg aacaggtcac
     1321 gtatgaaaaa tgcacgatgg acgacatcgg ctccgccgcc attcacgcca ccgtgtccgg
     1381 caacgtccat ttcgtagcgg acagcgacgc gcacgccatg gacatcctga agaggcttct
     1441 ttccttcctt ccttccaaca acacggaaga accgccccac aaactggaca ctccgctgga
     1501 cctgagcgct gacgaaggca tgagcgacct gattcccggc gacaaccgca cgccgctgga
     1561 cgtccagccc atcatcagcc gtctggtgga caacggggac ttcctggaag tacacaagga
     1621 cttcgccaaa aatgtcgtcg tcggattcgg ccgcatctgc ggcgtggtgg tcggcatcat
     1681 cgccaaccag cccaatgtga aagccggctg cctggatatc gactcctccg acaaggccgc
     1741 gcgcttcatc cgtttctgca acgcgttcaa tattccgttg gtgaacctgg tggacgtgcc
     1801 cggcttcctg cccggcaaga accaggaacg gggcggcatt atccgccacg gcgccaaact
     1861 tatcttcgcc tattcccagg ccacggtgcc caaagtcacc ctgatcatgc ggaaagccta
     1921 cggcggcgcc tacatcgcca tgtgctgcaa ggacctgggc gctgacgccg tcttcgcctg
     1981 gcctggtgcg gaaattgccg ttatgggtgc ggaaggcgcc gtcccggtac tctacggccg
     2041 cgaactgaag gctgtggaag acccggcgga aaaagccaag cgccagggag aacttctgga
     2101 agaataccgg gaagcctttt acaacccgta tgtggcggcc ggcatgggac agattacgga
     2161 agtcatcaat ccggaagaaa cccgcgccaa aatcgccttc gccctgcgca ccctgctgaa
     2221 caagaaggaa gtgcgcccgg ccaagaaaca cggcaacatt ccgctctaac atccatccca
     2281 acggattcat atgttactta caacactcgc ttttgccttc gcacagggca tcgccaacgt
     2341 tatgaacaat ctgaactatc aggttgtcgg catcatggtg gttatgctgt gcctgggagg
     2401 catggccgtc attctgaccg tcagcggctc catcgccgcc gccattcaga acagggccaa
     2461 agccaaaaca gccgctcccg tagccgtgtc tgccgccgct cccgctgcgg cgggcaaacc
     2521 gggcatgact ccggaaatgc tcgccatcct ttccgccgcc gtggattccg ccatgacgga
     2581 gcttacgccg gaaatggtgg ccgtcatctc cgccgccgtg gacgcaggcc tggacggcat
     2641 gagccaccgc atcgtggaaa tcaagcaatc cccgggttcc ggctatgcgg ctgcgggcag
     2701 ggcggaaatt ttcgcctccc accgcatccg gccttcccgc tgaactactg cattattcac
     2761 ccttaccccg cccaggcgga atcatttaac ttaatatccc ataccacaca ctattatgaa
     2821 gaaacttcgc atcaccgtag acggcaaagt atttgacgta tccgtagaac ttctggacca
     2881 ggtgtcctcc accactgcgg cgccggcccc cgcacctgtg gccgctcccg ctcctgcggc
     2941 ttccgccccc gtggccgccc cggccccggc tcccgcacct gcgccggctc cggccgccgc
     3001 cggcgcagga gacgttccca gcccgcttgc cgggaaggtc gtctccctgg acgtggcagc
     3061 aggcgcaccc gtgaaggccg gtgaccagat tctgacgctg gaagccatga agatgaacac
     3121 catcatctac gctcccgcct ccggcacgct caccgctttc tgcgtgaacc cgggcgacac
     3181 ggttcaggaa ggacaggcac tggccaaaat tggttaatcc cggcggcggc agcccggaaa
     3241 cgccaacagt cccgggctcc ggctcagata ataaaccgct annnnnnnnn naatattccc
     3301 tatgagtctt tttgattcat taatcacctt tttacagggg atgggcgtct tctccctatc
     3361 atggcagatg gtagggatgt ggggcattgc cattctcctc ctgtatctgg gtgtagccaa
     3421 gcaatacgaa ccgctcctga tggttcccat tgctttcggc gccctcattg ccaacattcc
     3481 ggataacgga atgctcatca cccagctgaa ccagcaggtc atctcctcca atgaacaggg
     3541 ggaagtaacc gccacgtctc tgaacaacgt ggggtacctg cgcgttcacg tggctccgct
     3601 tcagcaggct ccctccaagg tgccggccaa cctgaccacg cctgaatccc gtgcccagta
     3661 tcaggaaatc atgcagcagc ccatgcaggt ttaccccggc agccagctga ccgtttccaa
     3721 gatcaagtcc gtgcgggaat cccaggaaaa agcaaaagct gacgcggccc gcctgggcga
     3781 cgacagcctg acggtggacc ccaacctgaa ggatttccag aacgtgacgg aagacaacgg
     3841 caatgaaccg gtcttcctgc tcacgaacgg agaagggacc accgtcgtcc gccagcaggg
     3901 cgtcaattac tttgacacca gcggcaaccg gattccggtg gatctgaaaa cccagaagct
     3961 ggagcccctg gtggtttccg ccgcaggcaa atacgtggcc gtaggccagc atacccagga
     4021 actgctggtc acctccatcc acgggggcct gtatgactgg atcgggctgg gcatcaaggc
     4081 tgaaattttc ccgcccatca tctttctggg cgtaggagcc ctgacggact tcggcccgct
     4141 gcttgccgct ccgcgcaccc tgcttctggg cgcagcggcc caggtgggcg tcgccgccac
     4201 gttcttcatg gccctgttca tggggttcac cccgaatgaa tccgcgtcca tcggcatcat
     4261 tggcggcgct gacggcccca cctccatctt cttgacgatg aagctggcnn nnnnnnnnaa
     4321 gctggccccg cacctgctgg gcgccgtggc cgtggccgca tacacgtaca tgtccctggt
     4381 tccgctgata cagccgccca tcatggcgtt gctgacgacc aagaaggaac gcctcatccg
     4441 catgaaatcc ctgcgaacgg tcagcaagag cgaaaaactg tttttcgccg tgctggtaac
     4501 cattgtcacc attttgctga ttccggacgc atccccgctg atcggcatgc tgatgcttgg
     4561 caacttcctg cgcgaatgca aggtgacgga acgcctggtt caggcctccc agaatgaaat
     4621 catcaacatc gtcaccatct tcctgggaac ctccgtgggg ctcacgatgc agggcgaccg
     4681 cttcctgcag tcggaaacgc tgctgatcat ccttctgggt atcgtcgcct tcggcgtggc
     4741 aacagcgggc ggagtgattg ccgccaagat tatgaacctc atctggcgca agaatccggt
     4801 caaccccctg atcgggtccg caggcgtctc cgccgtcccg atggcagccc gcgtctccca
     4861 caatgtgggc cagaagtacg acccctccaa ctacctgctc atgcacgcca tgggcccgaa
     4921 cgttgcaggc gtgatcggca ccgcagtcat cgcgggctac tacatcgcca ctctggcgaa
     4981 ataaccagaa ttgaaaatta ctcccggcct cggcccgtcc catgaattcc gcagcctcat
     5041 tttccacccc tccggaggag gaaggaccat gcggcgactg gacttatcat gaatgggctg
     5101 aggctttttc caccaatgat ctggcccgca ccctcccccc ggggcatatt gccgtctgcc
     5161 gtgttcagac aggaggccgc ggcaggttca accgcaaatg gataggggag gaaggcggcc
     5221 tgtgggcatc cttcaccgtc cccctgtccg ctcctgagga tacagcggcc gacgtgcact
     5281 ggggccattt gcctctggtt gcggggctgg ccctgttcaa catgctccgc ggcatggggc
     5341 tggattccgt gcgcctgcgc tggccgaacg acctgctggc gggcaaatcc aaactggcgg
     5401 gaatactggt ggaacgcccg gcggagaaca tggccgtcat cggcatcggc atcaatgttt
     5461 tcaatgatgt atcctccatc gccggggaaa tcaaggaccc tccggcaagg ctggcggatc
     5521 ttgttcggga ctgcccttcc ctgcacgccg tcatggcttc cctgggcagt catttgaacc
     5581 aggttctttc cgtcttttcc cacggtggcg tccccgccct tcaggagggt ctgtcccggg
     5641 catgggccgg agaaaggccg gtttccattc ttacggatga cgaaaccgtc cggggcattt
     5701 ttacagggat tgacgatcag ggcaatcctg tgctatccct tccggccggc accgtccgca
     5761 ccattccggc gcacctgatc aacaggctcc tcgaagaatg agcctgccgc tccgttttac
     5821 acggggtttc tttctttttt catccaacaa aaatcactga catgagttac aaggtactga
     5881 caccagaaga agcagcaagc ctgatcaagc atggccacca tattgggctg agcggattca
     5941 cgcccgccgg aacggccaag gccgttacgg ctgcgctggc aaaaatcgca gaagcggaac
     6001 atgagaaggg gaaccctttc caggtgagcg tcttcaccgg tgcttccact ggcgattcct
     6061 gcgatggaat cctttcccgg gccaaggcaa tccgctaccg cgctccctac accaccaacg
     6121 ttgatttccg caaggcggtg aacaacgggg aaatcgccta taatgacatc catttgtccc
     6181 agatggccca ggaagtgcgc tacgggttca tgggcaacgt ggacatcgcc attattgaag
     6241 cctgtgaagt cacggccgac ggcaaaattt acctgacggc cgcgggcggg atcgctccca
     6301 ccatctgccg cctggcagac aaaattatcg tggaattaaa cgccgcccac agcaagagcg
     6361 ccatgggcct gcacgacgtt tacgaacccc tagatcctcc ctaccgccgc gaaatctcca
     6421 tcttcaaacc cagcgaccgc atcggcaagc cgtacatcca ggttgacccg aaaaagattg
     6481 tgggcgttgt ggaaaccaac tggccggatg aagcccgttc cttcgccgca gcggatcccc
     6541 tgaccgataa aatcgggcag aacgtggccg atttcctggc tgccgacatg aaacggggca
     6601 tcattccctc cacgttcctg cctctccagt ccggcgtagg caacatcgca aacgcggtgc
     6661 tgggcgccct gggccgcgac aagacaattc ccgcgttcga gatgtacacg gaagtcatcc
     6721 agaattccgt catcggcctg attcgggagg gccgcgtaaa attcggcagc gcctgctccc
     6781 tgaccgtgac gaacgactgc ctggaaggca tttacaggga tatggacttt ttccgcgaca
     6841 aactggtgct ccgtccctcg gaaatatcca acagcccgga agttatccgc cgtctcggcg
     6901 tcatctccat caacaccgcc attgaagccg acatttacgg gaacgtcaac tccacgcaca
     6961 ttggcggcac gaagatgatg aacggcatcg gcgggtccgg cgacttcacg cgcaacgcct
     7021 acatctccat tttcacctgc ccgtccgttg ccaaggacgg caagatcagc gccatcgtcc
     7081 ccatggtttc ccaccatgac catacggaac atgacgtcaa tatcattatt accgagcagg
     7141 gggtcgcgga cctgcgcggc aagagcccga aagaacgggc ccagaccatt attgaaaact
     7201 gcgtccaccc ggattacaaa aacatcctct gggattacct gaagctgtcc gacggcaaag
     7261 cccagacacc gcaatccatc agggccgctt tgggcatgca cgccgaactg gccagaagcg
     7321 gagacatgaa gaatgtcgac tgggcccagt ataagtaatt ccgcatgccg tcattcgcat
     7381 tggcatccat gaattcacgt taacccctca ggaccgcttc cgcaaaggga gcggtccttt
     7441 tcctttttcc catcccctct actccttctc ttcaccatga actggatgat ttacccggca
     7501 gccagggctt tcatcaaagt ctgctccgtt cttttcggcg cgggcgcagc agcggcagtc
     7561 ctcatccatc tgttcatgcc ttttttcctc cgctctcccc gaacagccgc gcccttcctg
     7621 cttttgggaa caggggcgga actgctctcc atcctttccc tgtccttcct catgttctgg
     7681 ggcgtcagag ttctgctggc ctcccgcgga agcagaataa caagaaatct gagcatgctg
     7741 gccttcctgc ccgccctgta cgccctcctc attccgtttg cgggcatgcc cgtcccatcg
     7801 caatatacgg aaatggacag ggtttgggag gccgtcctcc ttctggcggc cgtcacttct
     7861 ttcttttcct tcccttatac ggcgggatac ggtgccgcag gcaggagatt attcctggcc
     7921 tggggcatcg cggcggcagg ctgcggtttg cagagcgccc tgttttttct tgccgtcctg
     7981 ttgcgtcagt tcctgtccac cgcagttccc tccctggcag cgcctgttgc atggctggcc
     8041 gttcttctgt cctgcggcct ggaaatcatg ctggcgaccc tttccgctat tctggcgcag
     8101 cgcctgttta aagaggtcat gtccatagca tccatgccgg aaccgattga tccttccatg
     8161 ccgggcaacc gtccctgact ttcctcccct ccgtttttac cggcctgccg gaagagcacc
     8221 ctcattcccc ggcatgaaag gcttttacgg ctttgcgcaa aaagccgtcc ggaaatttcc
     8281 gccggtggaa cggaatccgt atggaaagca ttgccggaaa gcaacccgcc ccaccccgga
     8341 aagccgcggg ttcgcaggaa cacccctccc gtttccactc cggcggcaga cagccctatt
     8401 tcaccaattc atccagataa cggccataac cgttattatt catggctccg gcctgggagc
     8461 gcagcgtttc ctgggaaatc cagccgttat taaaggctat ctcctccagg caggctacct
     8521 tgaacccctg gtggtgctcc agagtacgaa cgaacatgga agcctccaga agggtatcgt
     8581 gcgtgcccgt atccagccac gtataaccgc gcgccagttt ttccacgcgc aacaggccct
     8641 gcttcaggta ttcctgattc acagaggtga tttccaactc gccgcgggaa gacttgggaa
     8701 tccgtttggc tatctccacc acccggttgt cgtaaaaata gaggcccgtc accgcaatat
     8761 ccgatttggg cctgagcggt ttttcctcaa tggaaaccgc cttcccctcc tcattgaatt
     8821 ccactacccc gaaacgctgc gggtcatgca cctggtaacc gaaaatggtc gctccgctcg
     8881 tcagttcggc ggccctcctc agcttctccg tcaggccacg cccgtaaaaa atattgtccc
     8941 ccagcaccag ggcaacggaa tcctttccta tgaactcctc tccaataata aaggcctgag
     9001 ccagcccctc cggcctgggt tgttccctgt attcaaagga aacgccgaac ctgctgccgt
     9061 cccccagcaa atcccggtac aggggcagat cccggggcgt ggaaataaca aggatttccc
     9121 gtatcccggc cagcatcagc acggagatgg gataataaac catcggctta tcataaacgg
     9181 gcagcaattg cttgctgacg gaaagcgtaa cgggatgcag acgcgtgccg cttcccccgg
     9241 ccagaacaat acccttcata tcaaattcct agccattggt tccaagacgt tccaggcggt
     9301 attccccgga caggatgccc cgccaccatt cctcatggtc cagataccac tgaatggtct
     9361 ttctgaatcc ggaagaatgg tcctggcgcg gagtccaccc caattccctc cgtattttgg
     9421 aagcgtcaat cgcatagcgc aggtcatggc ccggcctgtc ctgcacaaag gagatttgct
     9481 cccggtagct ccggccgtcc ggccggggcc gcagttcatc cagatgggaa cacagcagct
     9541 ccaccagctc cagattggtt ttctcgttat tgccgccgat gttgtacgtt tcccccggtt
     9601 ttccgcagga aacgaccgtc aacagagcct cgcagtgatc ccccacatac agccagtccc
     9661 gcacgttttc ccctttgccg tatacaggaa tgggttcccc gcccagcgct ttcaggataa
     9721 cgacgggtat cagcttttcc gggaactggc aggggccgta attgttggaa cagttggtga
     9781 tcagcacggg cagaccgtac gtatcgtgcc aggcgcgcac caggtggtcg ctggaggcct
     9841 tgctggcgga atacggggaa tgggggcgat acggcgtgga ctccgtga
//
