LOCUS       c00062_gnlPro..         5640 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODPKDEEL_62.
ACCESSION   c00062_gnlPro..
VERSION     c00062_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:28:58
            Original ID  :: gnl|Prokka|ODPKDEEL_62
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5640
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5640
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[716:5640]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      717..5640
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5640
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5640
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             103..339
                     /locus_tag="ctg62_1"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTAKTRKTKTGPAKLKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFLTLDEGFKRFEAWKQDLLKSRL"
     CDS             306..647
                     /locus_tag="ctg62_2"
                     /transl_table=11
                     /translation="MEARPTQKQVITSSLFWESYDNVYVQGLDLFGFYQAELYANKIKS
                     ILYELDQTYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KKTRNIHIE"
     CDS             complement(717..1760)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_3"
                     /sec_met_domain="IlvN (E-value: 1.1e-47, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.5e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(1810..2535)
                     /locus_tag="ctg62_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(2542..3096)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_5"
                     /sec_met_domain="ALS_ss_C (E-value: 1.8e-17, bitscore:
                     52.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(3112..4815)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.7e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELRAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             complement(4849..5640)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_7"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-85, bitscore:
                     275.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQES
                     YYKELDTDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKV
                     FDSQDAACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITD
                     GRFSGGTSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAE
                     EARGKKAFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
ORIGIN
        1 tgagttaatc ctatagacct acttttttcc ttaccaaata tcttattaca tggaaattat
       61 tccatacatt tgccacagta ctaattaata acgattacga ctatgacaaa attaagcaac
      121 atccccgcca aggaaactac ggccaagacc gcaaagacac gtaagaccaa gaccggaccc
      181 gcaaagctca agtgggatcc caccaagccg gtgcaattca cccaagaaga gatctgggaa
      241 catatccatg agattgagaa gggaccgttc ctaaccctag atgaaggttt taaacgtttt
      301 gaggcatgga agcaagacct actcaaaagc aggttataac cagtagttta ttttgggaaa
      361 gttacgataa tgtatatgtt caaggccttg acttatttgg attctaccaa gcggaattat
      421 acgctaacaa gataaaatcc atcttatacg agttagacca aacctatcct tattatcccg
      481 aatgccgaca cctagccacg aaaagccgca tgtaccggaa catcatccta gattcacacc
      541 ttatcatcta ccgcatcacc gaggaacgca tcgaggtgct ggacatcgtc cattcagcat
      601 ccagcatgcg aaagatcaag aagactagga atatccacat cgaataacac aaagaaaggc
      661 gagccacccg taagtgaccc gcctcttttt gctgatatat aaggattaag attggattag
      721 ttgttctccg gacgaagctt acgtacagta acagctgtct gccacatctc gctctcgcgc
      781 aatgccttca attcagcctc caatttctca cgataatccg gcttagagtt tgagtcgata
      841 gagatctgag cctcgttacc gcattttacg tttgcgtaca atttctcgac aaccggcttg
      901 attgcgtcgt ggaacggacc catccagtcc aaagcgccac gctgggcggt agtagagcag
      961 ttcgcgtaca tccagtccat accattcttg gcgaataaag gcatcaagga ttgagtcaac
     1021 tcctcgaccg tctcgttgaa agcctcggaa ggagtatgtc cattctcgcg caatacctca
     1081 tactgggcca acaacaaacc ttggatagcg cccatcaagg aaccacgctc accagtcaaa
     1141 tcggaagtag cctcacggat gaaagtcgtc tcgaacaagt agccggaacc gataccgata
     1201 cccaacgcca acgtacgatc catcgccttg ccagtagcgt cttgatagat agcgaaagaa
     1261 gagttcaagc cacgaccctc aaggaacatg gaacgcaaag acgtaccaga ccccttcgga
     1321 gcgaccatga tcacgtcaat atccgcggga ggaacaacgc ccgtacgatc gttccaagtg
     1381 atcgcaaaac catgagagaa atacagggcc ttgccagctg tcaaataagg cttcatcgta
     1441 ggccatacag acattacggc agcgtcggac aacaagcaca tgatgatcgt ggccttgtcg
     1501 caagcctcct cgataccgaa cagagtctca cccggaaccc atccgtcctc aaccgcttta
     1561 tcgtaagtct taccttggcg ctggccaacg attacgttga agccattgtc acgaaggttc
     1621 aatgactgtc ccggtccctg tacgccatag ccgataacag cgattgtctc atcttttaat
     1681 atctctcttg ccttttccaa cggaaattcc tcgcgggtca ttacattctc tacaacaccg
     1741 ccaaaattca tttgtgccat tttcttttta actattaatg tttaaaaacc tatttatgta
     1801 tctcttttat tatctccaag taaccgccgc acgacagatc gcctttccct catggcaaat
     1861 agccatgtct tgcttatcgg gagcggactc cgccttatga agcgtaagcg gcataccttg
     1921 tttaccctcg gattggtagg cgatctccag acggccgatc tcacgggtct tgaactgatc
     1981 gatatcgaac aaatccagca ggtgctcgat atacttcacg ctattgaagt gaccgttgat
     2041 atccaagtcg ctgtatttga tcgaatacgg gattccctcc gccttattct ccgccggcat
     2101 gatcttgccc ggcttctcga tcgggcacgg acgctcgtcg atatatttgc ccaatgcctc
     2161 tatatccaat aaggtaggac ggcgggtctc cacgtcgata gccgcccaaa tagaacgggc
     2221 gaatccaaag gttttcccat tctcatccgc cagctcgaaa caacgactgg tgaagaggcg
     2281 tccgacctca tcgatccaag tgtatagatt aatcttatcg aaggcggtag gatattcctt
     2341 catctcgata gccagacggg acaacaccca agccgtatga cgctccgaca tatcattgaa
     2401 accgaaccca cgctctccgg catggctgga agcggcgtga atcaaatagt taccaatcat
     2461 agggagcgtt acacgtcccc tgaaatccat caaatacggc tccgccacga aatgaaataa
     2521 tcctactttc tccatatctt attattgttg cttttcatgt aactttcgct ccatatcggc
     2581 caacatatcg ctcaagcgct ccaccttgct cttcgtgata gccacacgtc cggagcggat
     2641 gaattgcagg acaccgatcg tctcgctcaa ctcattgaac aaggcttgtg tctcgtcata
     2701 gtggccactc ttctccaaca ccacgcaggc ctcgttcatc tccaagatac gagcgttgta
     2761 tttacggatc aatccctcca cggttcccat cttgatgaaa agctcggtac ttagcttata
     2821 aagggcgatc tcttgataaa ccagatcctc atccgtatta taataagcct tcaagatatc
     2881 cacacgttta tcgatctgtt tcaccacctt atcgatcata tcctcatcgg cgaaggtcgt
     2941 gatcgtaaac ttatggatgc ccttgatagc ggacggagag acggacagag tctcgatgtt
     3001 cagctgtcgg cgtgtaaaga taatcgttat ctggttcaaa agacctacga tattctctga
     3061 aaagataata acggtatata atttctttgt tgtcatagct tcatctcctc cttatttctc
     3121 gtctcccata atcatgtttg tcacgcttcc cccggcagga accatcggat ataccattcc
     3181 gcaagtctcc acgttagcga ccaacacgta agcgccgtcg tggtttagca tctcggcgat
     3241 agcgtcgtcc aattcctccc gcttttcaac ggcacggcca gcgataccat aggctttagc
     3301 gatcgccacg aaatccggat tctccatgat ggtgtttgaa taacgctcgt ggaagaacaa
     3361 ttcttgccac tgacgtacca tacctaagaa gttattatta agaatgataa tcttcacgtt
     3421 cagtttctcc tgcatgatgg tacccaattc ctgaatcgtc atctgcatac ccccatcacc
     3481 ggtaaagaag cagaccgtac ggtccggagc cccgaactta gcgcccatag cggccggcag
     3541 accaaatccc atcgtaccta aacctccgga agtcaccacg ctacgggttt gtttatattt
     3601 gaaatagcgg acacccatca tctggttctg cccaacgtcg gtcaccaata cagcgtcgtt
     3661 accggtcgcc tcggaaacct tacggactac ctcgcccatt ttcagttggc cctcggtcgg
     3721 atacaattcc ttctcgatta ccttatcgta ttcctctttc tcgtcccgat cgaactcggc
     3781 attccattcc ggacgtttac gttcttccaa caacgccgtg atcatcggta tcgtgtgctt
     3841 ggcattaccc agcaccttta catctacggg gacgttctta ccgatttccg agttgtcgat
     3901 atccagatgg ataatcttgg cttgcttagc gtatgtcttt aaatcgccag tcacacggtc
     3961 gtcgaaacgc ataccgatag cgatcaatac atcacactca ttcgttttcc ggttcggccc
     4021 tacgtttcca tgcataccga gcattccctt gttcaatggg aaatcggttg gcaacgcaga
     4081 taagcccaat accgtagatc cggcaggtat atcattcttt tggagaaacg ctctcaattc
     4141 ctcttccgca ccgcctaaca atactccctg cccgaccaga cagaagggtt tcttcgcctc
     4201 attgattaaa tcggcggcgg ccttgatacg atcctttttg atatccggct ccggctgata
     4261 actacgtacg taatctacct tcttatattc atagtccacc agccctactt gcgcgtcctt
     4321 cgctaaatcc agcacaactg gacccggacg gcctgtagaa gcgatataaa aagcacgaga
     4381 aacagcccat gcgatctcct ccggcttgcg gatttgataa gcccatttcg tgatcggttg
     4441 cgtgatgcca atcacgtcga cttcctgaaa agcatcggtt cccaacaacg gcgagggtac
     4501 ttgaccggcg attacgacca ttggcgtact atccatcagc gcatcagcga tacccgtgat
     4561 ggtattcgta gcgcccgggc cggaagtaac caacgtcact cctaccttgc cggatacacg
     4621 ggcatatcct tgagccgcat gggtagcgcc ttgctcgtgg cgcaccaata catgcctcaa
     4681 ctggtcccta taatcatata aactgtcgta aataggtatc gcctgtccgc cgggataacc
     4741 gaagatagta tctactcctt cagcaatcaa cgctttcagc aaagcttccg aaccggttat
     4801 cttttgtttc tccataagaa ataacgtgtt taatgtatat tattggcttt aatcttcaac
     4861 aatccttaca cctcccttat cggcggagct aaccatcttc ccgtacgctc tcaacgcttt
     4921 cgagacctca cgctgacgcg tcggcggcgt aaaggctttc tttccacgcg cctcttccgc
     4981 tttacggcgc tcggccaact cctcgtcgct cagccgcacg ttgatggaac gttccgggat
     5041 attgatctcg atgatatccc cgtctctcac cagtccgata gcgccaccgg aagcggcctc
     5101 aggagagata tgcccgatag aaagaccgga cgtaccgcca ctgaaacgac catccgtgat
     5161 caaggcgcac tccttaccta agtgacggct ctttatataa gaggtaggat ataacatctc
     5221 ttgcattccc ggccctcctt tcggaccctc atacgtgatg acgaccacat cgcctgaaac
     5281 gaccttgcct cctaaaatgc cctcgcaagc ggcatcctgt gaatcgaaga ctttcgccgg
     5341 gccggagaat ttccaaatac tctcatccac gccggcggtt tttacgacac atccgtccaa
     5401 ggcgatattc cctctcaaaa cagccaagcc gccatccttg gaataagcgt gctccacgtc
     5461 acggatacaa ccttcggcac gatccgtatc taattcctta taataagatt cttgggaacc
     5521 catctggata ctgaaccgat gagcgggagc gctcttgtat ttacggatcg cctcctccgt
     5581 tacgttcggg gaagtgacgg cgtatttatc aacagcctcg gccaaggtca ggccgtccgc
//
