LOCUS       c00005_gnlPro..        16963 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BOPDAFEH_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:48:52
            Original ID  :: gnl|Prokka|BOPDAFEH_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16963
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16963
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5998:8974]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5999..8974
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16963
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16963
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..991)
                     /locus_tag="ctg5_1"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQAMGENRLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTVSKEVTLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGG
                     GSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAG
                     LYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSRSEEHT"
     CDS             complement(1038..1388)
                     /locus_tag="ctg5_2"
                     /transl_table=11
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPFHK
                     TDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIVPF
                     RGRRTLRAPPIF"
     CDS             complement(1474..3027)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-48, bitscore:
                     155.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESTLKEQLKGIFAGLNANYTFDISISPAYESRQELLDLLGDVA
                     SCSDKISMQVSDGEGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASAAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIVATGASWRKLNVPGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFKEIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLD
                     "
     CDS             complement(3047..3613)
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(3834..5114)
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGEN
                     EALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTKSK
                     LGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQE
                     FMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDALNSII
                     AAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLEKLINE
                     YPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCGNSILIK
                     VNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSD
                     RMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             complement(5222..5800)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MKTPQEIAEMISKRFYPLPDADLDSLASIIESSKAAKGELLLDNG
                     QISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNIVICIASTFQREPTRLLIEALEPTV
                     YHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQEKADSWRFESARKRYLRFQQEYPE
                     AAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             complement(5999..6733)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_7"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-33, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             complement(6734..8974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_8"
                     /sec_met_domain="Gly_radical (E-value: 4.3e-46, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.3e-282, bitscore:
                     925.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRRVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             complement(9145..11448)
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MEQCEENSQENDDVIIEKEISKLIEEQRLFTESIYACLPVGIEIY
                     DAHGVLRSINDHALRMYGVDDRTSVVNIVNLYKSPFVDSELLARIQSGEDISLEFEYDF
                     DRVNKDAYYSSYNKDTMIYGVKVIPIWSRKKHLIGHILLANDMTSVKEVEFRTEESKKN
                     LEMAMKAANMASWVYDVNKKVFNPLYGLTVAKKNMPMEAVLDILHPQDRAPLIRLFSQL
                     IGNEIEQGQMTLRFYNEQEEMYRYYESRMRLSTEHRGKLQIIGTQMDITERLQMAKKAQ
                     DLIAKRDLAMKVSNIVHWDFDVNSQKFESYNDPINDYVSDRLLTVSEYMDVIYPEDRSV
                     FYDAMQSLIAGKNVTINFTCRIQTKYDETWQYCDFMGVPFDQDENGDIIRYTGFRQNIP
                     KIQQLNRELKERNYKIELSFKTVGMSYWDFDVKSLKFSAFNDPINDFYSEKTITPEDYL
                     NATHPDDVVFVRKYMEHMFRGIDKDFNVKYRSKTKWDDEWQTLLVTGIQVERDKEGHVT
                     RYTGITINNTKWEKMIQQLKELKEKAELSDRLKSAFLANMSHEIRTPLNAIVGFSELMV
                     TCDDPEEKKEYINIIQSNNELLLRLINDILDLSKIESGIIERRKENFNLAKVCNELFVT
                     IQAKMTNPNVELRLDGPNSECWVLLDRNRLKQVWMNFLTNAVKCTKSGYIKMGYGIERK
                     GLRIYVEDTGIGIPDDLHDKVFTRFEKLNEFSQGTGLGLTISRAIVEAAGGEVGFTSKL
                     GVGSTFWAWLPLRP"
     CDS             11605..15645
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MRFTRLILALTSFLILITQTDLFASTVLHKTSMVDLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVDTDNKLYRQHVDGKGKEFLFDLPEMTKQYGNIIKICTFQSNVYIVFRNGNILDL
                     SQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIRMFYDKPDLFGSILLKDLPINIQNP
                     IRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKMIPQSAITHFTTADGLSSNRVYCFQ
                     KSEYHPCIWIGTEGPGLTCYSYKEKRIKTIPQREDTTPLRYVHSICEVDDSTLWLATTG
                     NGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEIQSMVYDNDSTLFLGSRGGYGVIRF
                     NIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFYAGASSGLTRIKFRGGKMRLRQFDK
                     SDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRNNFFHNYHQPYFSVTEFSDDAYWKC
                     PYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFELQMDKQILPLYKDISRNGVTVPAD
                     VQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKLQKTNKVTFMNLPYGEYLLKVRYRN
                     DVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGTVLLIIATYRIHHQILKKQKQIADK
                     IKEEQKEKLYESKLNFFTHITHELCTPLTLINGVENYIQAYAATSKDKTLEKYTSVLRE
                     NVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSSLLRTQFEWFYPLSEQHQIQFKIDA
                     PKELYWNTDSVYFKKILANLISNAFKYTEDGGTVRISLHEEENFLVLKVYNTGKGIEEA
                     DMQNIFDRYRILGTMDNDDNRQNTTRNGLGLFICHSLVQSLGGKIDIESEVGQYAEFTV
                     TLPFGIVEETSDNTIDEEIPVSLPSPNTDIQEPQISHTAQKETEDKPMILVIDDHKDIV
                     WLITETLSSEYQVQEAYNAEKALEFLKQYTPSLIITDIMMPNMDGLELISLIKENKYTR
                     HIPLIIISAKISDQEQAAGLNIGADAYLTKPFSPTVLLSVVNRLMTNQRELKEYFYSPE
                     SAYQYTEGQLLHQEDKEFLDTVTSIIKENVSKEGLGPELVADALNINTRILYRRFKKIS
                     TMTPSDFIKDYRLNYAAQLLVNTNMSVQEIIYNVGISNKSYFYREFARKYNMTPKEYRT
                     KEA"
     CDS             15848..16963
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MEKKSEGKTRKCLTLLGGRTSLLLCLSLMFQSSYAAGDSTVPEMG
                     NMEIHQIAQQSSTIKGVVKDQKGEPLIGVSIVVKGTTNGTASDFDGNFTLDVPDNSTLV
                     FSFIGFKPQEVRYTGQKTLNIVLAEDSETLDEVVVVGYGSQKKGEITSSVTSVKASDFN
                     KAPVVNPMQLVEGRVAGLTVSRGSTDPNGEVKVQMRGASSLKGSNEPLVIIDGMPGNMT
                     SLNAIAPEDIEAIDVLKDGSAAAIYGTRGNNGVIIVSTRRPQAGTTQVDYSGYIMHEAV
                     YKRPEILNGDEFVAYGKETNNANIRDFGGRDNHYDALLNKSNFTHVHNLTATGGNGKTN
                     YRASLNYKKNDGMIRNTSRGTINGSIAVNQRA"
ORIGIN
        1 acgtgtgctc ttccgatcta ctataagtac tcgttttcag gtacgaacgg aaaccaaccg
       61 tttgattctt caatttaggc aactccgtaa aaccatctcc atcctgatca aaaccggaac
      121 gatgacggtt ctggccaaaa agatataagc ccgctttccc attttccgat accaaagagg
      181 catttagggt cgtattatta tcgaaagcgg atgtcccacc gatcgaggtt aacgtatgcg
      241 acaattcccc ggaatttctc aagggctcct tcgtgatgat attaattgtc ccggcgatag
      301 cggacgagcc gaacagtgcc gatccccctc ctcgcatcac ctctacccgc tcgatcatat
      361 tcgccggtat ttgctcaagc ccatatacgc cggataaagc gctgaatatg ggacgtgaat
      421 caatcagtat ttgggtataa ggtccgtcta atccattgat ccggacttgc tggaaaccgc
      481 aattctggca attcgtctct acccgtacac ccggttggaa atttagtccc tgtgccaaat
      541 tcaccgcatt agtcgtagta aaaaccttcg catccaatac attcactaat gtgggagcca
      601 accggcggga agtttccgca cgattcgcag ataccaccac gccatccaag gcgatctggt
      661 cttcttccag ttctacatta atctctaagg tttttccttt ctttagggtc acttctttag
      721 agacagtctt atacccgagc gctttatatt ctagcgtaaa tttaccttcc ggcagattct
      781 tcaggaaata atgtcccgag ttatcggtgg tcgtaccgat cgtggtacct tttaacaata
      841 cgttgataaa gggaagatgt tcccctgttt tcttatccaa tacatgtccg aaaacatttg
      901 cgtctgagtc gtttagacgg ttctctccca tggcctgagc taccgttagg gcacagcaca
      961 ggcatagtat aaagatgaaa aatttattca ttttaattta ttctgataag taatacaatg
     1021 ttattaatct cacaatatca gaatatggga ggagcacgaa gcgtacgtct tccccggaag
     1081 ggaacgatat agtccggata gaccggagcg aaagataagt tacggataaa ggaataaaaa
     1141 gccgccagca gaatagcgac gaaagccgca cctgttatct gcaagacaga taactgatga
     1201 agcaactgaa actcggcgta gccatgttca tggtccggac gaccatcgtc cgttttatga
     1261 aacgggtgag aatggacgat cgttaccccg ttgacaatat gaacgtgagt aaacgcaata
     1321 atacatccca aataggctat gaacagcgca gggagtaata tcctcagata ttttcttaat
     1381 ctatccatct cttttctctc gatcgcaaat atagtaatat aaccgataaa aaagatacgc
     1441 tgttcaaaaa ttacctattt gtaggtactt tcctcaatca agtacgccac gtacccgatc
     1501 ttcaaaggcc gaaagggccg ctttggctcc ttctcccata gaaataatga tttgcttaaa
     1561 gggtacggtg gaaacgtcgc ccgctgcata aatacccggg acattcgtcc ggcaatgtgc
     1621 gtcaatcacg atctcaccgg gacgatttgt ttcgacaatc tccttaaaga caccactatt
     1681 agcggctaag ccgatttgaa caaaaatacc gtctaaatga ataacacgct cttcccctgt
     1741 cttacgatcc tttgtacgga taccggttac cttgtcgcca tttccaacca cctcggttgt
     1801 ttgtgaacta acaaagatct cgacattcgg caaactcttc gctttctctt gcaagacttg
     1861 atccgctttt aactcatcca taaactccaa aacggttact ttcgaacaga tccccgccaa
     1921 atcaatagcc gcctcgatac cggaatttcc accgccaacc acggcaacat gttttccctt
     1981 ataaaacgga ccgtcgcaat gaggacaaaa agccactcca cgccctatat actctgcctc
     2041 acccggtaca ttcaatttac gccagctagc gcccgtagcg acaataaccg ccggagcctt
     2101 gaatatctca cctccagccg tagataaaac cttctcgttt ccttctatcg ttaccttctc
     2161 tatacgacga tgctccagca ggtcaatcgg atattgccgc atatgcaagc gcagattgtc
     2221 agccaactgg gtacctgttg tctccggaac tgaaatcaga ttctcaattc ctaccgtctc
     2281 cttcacctgc ccgccgatac gctccgccac gacagcgaca ctcagcccct ttcgtgcgga
     2341 ataaatagcg gcagaagcac cagccggacc cccaccgacc acaaccacgt catatcgttt
     2401 taccgtcttc tccgttaggc tctcattgat tccatactga gcttccagct tcgataacaa
     2461 ttctccgaat tccccacgtc ctacatggat cagttttcca tccgcaaaga cagaggggac
     2521 gccttgtatc ttcaaggcat caacttccgc ttgattgata gccccatcta ccatctcatg
     2581 atggatctga ggatttaaag tcgtcatagc gtttaatgcc tgtaccacat ccgggcaatt
     2641 cgtacaagtc aaagagacat aggtcgtcag atgtatcggg ccattcaagg ctttaacacg
     2701 attacaaatg ctctcgtccg gaaaattctt gcctttccca tctgaattca agatcgccaa
     2761 cagtaaggaa gtaaactcgt gtccattagg tactccacga aacttaatcc ccgttttcgc
     2821 tccatccttt aacaaaatga attccaatcc ctccccatca gatacttgca tagatatttt
     2881 atccgaacaa gaggcaacat cacctaataa atccaacaat tcctgtctac tttcatacgc
     2941 aggagagatc gatatatcaa aggtataatt cgcatttaac cctgcgaata tacctttcaa
     3001 ttgttctttt aatgttgatt ctaacacgat ctatactctt aattatttag attttcccta
     3061 ccaagtcaat gctaggtttc aaggtagcct cccctttctt ccatttagcg ggacaaacct
     3121 caccatcatg tgaagcgaca aactgagcgg cttcaacttt acgaagtaac tcggaagcgt
     3181 cacgaccgat attgttatca tgaatctcgg ccactttgat ctttccttcc ggatttacca
     3241 agaaagtgcc acggtatgcc ataccctctt cctcaatcat cacaccaaac gcacgactca
     3301 gtgctccagt gggatccgcc aacatcggat attggatctt acggatagtc tcggaagcgt
     3361 catgccaagc tttatgtaca aaatgagagt ctgtacttac agagtaaatt tctactccca
     3421 ttgatttaaa ctgctcatac ttctcagcca tatcgaccaa ctctgttgga caaacaaatg
     3481 taaaatcggc cgggtagaag aaaaagatag cccacttacc caagacgtcc tcgttggtta
     3541 cagtcttgaa attaccattt tgaaaagctt gtactttaaa ctccggaagt tgagaattaa
     3601 taatcggttc catacttgtt cctattttta aatgaatact atttgttttt atttccgata
     3661 caaaaatata acatatttat tcattaaaac aatttttcta atcgatatat tttatgaggt
     3721 tatagataat actttatcaa tcaataaaaa gggcctatcc tcacggataa gcccttcaat
     3781 atcttgggtt ttggattact acataattag cgattataat ttactttata tacttaattg
     3841 attcttttgt atccgtatac ggcacggtct cccaattcct cctcgatacg aagcagctgg
     3901 ttatatttag ccatacggtc cgaacgactt aatgatcccg tcttgatctg tccgctattg
     3961 gtagcgacag cgatatcggc gatcgtagcg tcttccgtct caccggaacg gtgtgaagta
     4021 acggtcgtgt atccatgacg gtgagccatc tcgatagcgt tcagtgtctc cgtcaaggaa
     4081 ccgatctgat ttaccttgat caagattgag ttaccgcaac cttctttaat accccttgaa
     4141 aggaactcta catttgtcac gaacaaatca tctccgacta attggcaatg gttaccaata
     4201 cgatctgtca gtttcttcca accagcccaa tcattctcac tcataccatc ctcaatggaa
     4261 tcgatcgggt attcgttgat cagcttttcc agataatcca cttgttcgtc ggaagtacgt
     4321 ttcactcctt tttctccttc aaacttcgtg taatcgtaga ttccatcctt ataaaactca
     4381 gaagaagcgc aatccatacc gatcatcaca tccttgcccg gttcataacc agccgccttg
     4441 atagcggcga taattgagtt caaggcatct tccgtacctt ccaaattcgg ggcgaaacca
     4501 ccctcatcac caacagcggt acttaaccca cgatcgtgca ataccttttt caacgcatgg
     4561 aatacctcag cgcccatacg taagccttcc ttgaaagaag cggcacctac cggacgaatc
     4621 ataaactctt ggaaagcgat cggagcgtcg ctatgcgaac cgccattgat tatattcatc
     4681 atcggaacag gcatcacgta ggtattcgtt ccaccaatat atctatataa aggaatatcc
     4741 aaataatttg cggcagcttt cgctacagct aaagaaacgc caaggatagc gttcgcacct
     4801 agtttcgatt tagttttcgt accgtccaaa gccaacatcg catgatcgat acctatctga
     4861 tccaaggcag acatcccctt caatgccgga gcgataatcg tattgatatt ctcaaccgct
     4921 ttcaatacgc ctttaccacc ataacgcttc ttatcgccat cacgcaactc caaagcctcg
     4981 ttctcgccgg tggacgcacc ggaaggcaca gacgcacggc ccataacgcc ggactctagt
     5041 aaaatatcaa cctctactgt cgggttacct cttgaatcta ggatctcacg tcctgtaatc
     5101 ttttctattt tcattgcttc tacgtttttt aaactgacgc aaatatagat ggattacttg
     5161 aaccgtgaaa tcaccacaaa ttgctatttt cacctcaata atacctgaat gtaggtagag
     5221 actacaacac tcccgcccgc acccggctca aagattcggg tgtcatcaat aaatacgagg
     5281 cgatatgatt gacagaagca cgtttcgctg cttccggata ttcctgttga aaacgcagat
     5341 aacgttttct tgccgactca aaacgccaag agtccgcttt ctcttgcgaa agcatcaaag
     5401 cccactccag tattttctgg tacaatctat taatagctaa agatgttttc aataaatcgc
     5461 taaattccga aaaagagatc cggtgataaa ccgtcggttc caatgcctcg attaataaac
     5521 gcgtcggttc tctttggaat gtgctggcta tacaaataac gatatttccc tcacaggaga
     5581 aatgctcggt aatatcacgt ttattcttat agtaaaactg gcgtaataat cccgattcca
     5641 cataatataa atatttagat atttgtccgt tatccaacaa taattctcct ttcgcagcct
     5701 tacttgattc tatgatcgag gccagagaat ccaaatccgc atcgggtaat ggataaaaac
     5761 gtttggatat catttcggct atttcttgtg gtgtcttcat actattcatc attttctgat
     5821 ctatatcatt ttttatctcc ttacaaaaat agatatttgt tgcatataac aaaacaaaca
     5881 catattaaat agtcaaggtt agtctaggca aaaaattatt actatcgttt aaaagctaat
     5941 cggattagat tgttttccct gattagctgt tgcataatcg caaggcttga tcgagagatc
     6001 aggccttgtt attttctggt ttgtagcgag agaatatcgc tttcgcatta tctaaacgtt
     6061 cttttgataa gggttccacc ccctttaacg gataatcgag acctaattgc tcatatttat
     6121 aggttcccat cgtatgataa ggcaataatt ccactttgcg aaccacttta tatgaactga
     6181 cataccgagc taacgcctcc agccactcgt cattatccgt atatccgggg acaataacat
     6241 ggcgaatcca agtatctatg ccacgtctct ccaattcatc caagaacaga agcgtattat
     6301 cctgcttgac acccgccagt aacggatgta aatccgggtt taaggttttg atgtccaata
     6361 acactaagtc cgcataatcc aagacttccc aagcttttga ggtacatacg aaaccagatg
     6421 tgtccaaagc tgtgtgaaga ccttgctctt ggcacaaacg gaaaaactct ttcagaaact
     6481 caggttgcaa taaaggttcc ccaccggtaa cagtcacccc cccacgggcg ataaaactct
     6541 tataccgtaa gacttccgtc aatagctcgc cgggagtcat ctgatatttc accttccctt
     6601 tcgggttcca agtatccggg ttatggcaat acaggcaacg caacgggcag ccctgcataa
     6661 aaacgacaaa gcgaattccg ggaccatcta cggtcccgaa actctctaat gaatgtatct
     6721 taccttttat cacttacagt gaatggttaa tggttcttga aataacatcc aactgttgtt
     6781 cacgagtcag tttcacgaag tttaccgcat atccggatac acggatcgta agttgcggat
     6841 atttctcagg atgttccata gcgtcgatca acaaatcctt atcaaatacg ttaacattca
     6901 gatgctgacc tccatccgga gtaaaatagc catccaataa gctaaccaga ttattgatct
     6961 gcacttcacg ctcctttccc aacgtagccg gagaaacagc gaaagtataa gagataccgt
     7021 cgtgcgcatg ctggaatgga agcttcgcta ccgaagctag cgcagcgata gcacctttcg
     7081 tatcacgacc gttcataggg ttcgcgcccg gagcgaaagg agttccaccg atacggccat
     7141 ccggtgtcgt accagtcttc ttaccatata ccacattaga ggtgatcgta aggatggact
     7201 gcgtaggttt cgcatggcga taggtctcgt gctgacgcaa atattccatg aacttctcgg
     7261 tgatctctac agcgatacta tccgtacgat cgtcgttatt accgaaagga acatattcgc
     7321 cctcacgttc gaaatcaacc gccaagccac gctcgtcacg gatcacacgt actttcgtat
     7381 cacggatagc agccaacgaa tcggcaacga tagaaagacc ggcgatacct gtcgcacgga
     7441 tacgctctac atctccatcg tgaagcgaca tctcgaatgc ctcatatgcg tatttatcat
     7501 gcatataatg gattatcttc aaggcgttca catacacttt cgccaaccag cgcatcattt
     7561 gctcatactt agccatcacc tcatcgtatt ccagatactc gccgcgaacc ggctcgaaca
     7621 tcggggctac ctgtacgccg ctgcgctcat cccgtcctcc gttgatcgca tataataaac
     7681 atttcgccaa attcgcacgg gctccgaaga actgcatctg cttaccgatc ttcataggag
     7741 aaacgcaaca agcgatacca taatcatctc cataatccgg acgcatcaaa tcgtcgttct
     7801 catattggat agccgatgta tcgatagaga ccttggcaca gaaacgtttc cagttctcgg
     7861 gagcgttctt aaaccacaga accgtcaaat tgggttctgg tgccggacct agattatata
     7921 atgtatggag ataacgatag gaagttcttg ttaccaaaga acggccatcc actccttggc
     7981 cgcccaagga ctctgttacc caaaccggat caccggagaa caaatcattg tattccggcg
     8041 tacgtaagaa acgaacgata cgcaacttga tgatcagctg gtctaccaat tcttgcgcct
     8101 cctcttcggt caacttaccc tcacggatgt ctttctcgat ataaatatcc aaaaacgtag
     8161 aagtacgtcc gatagacatc gccgcgccat cttggtcttt taccgccgcc agataagcta
     8221 agtacacaaa ctgaactgcc tcacgagcgt tttgtgccgg acgagtcaca tcaaagccat
     8281 agctagcgca cattttctcg aacgctttca aagccttgat ctgttcggaa atctcctcac
     8341 ggctctggat gatctcttcc gtgatctctt ggatatccaa acgattcaag aaacgctttt
     8401 tctcctcgat caagattgcc gtaccatata aagcgacacg acgatagtca ccaataatac
     8461 gtcctctacc atacgcgtcg ggcagaccgg tgataatagc cgaacgacgt gcggcaatca
     8521 tctcttccgt atatgcggag aaaacgcctt cgttatgagt tttacggtac ttcgtgaaga
     8581 tctctttcgt catcgggtcc aaatgataac cataagcttc caagctattc tcaaccatac
     8641 ggataccgcc cttcgggaag ataccacgtt tcagcggagc atcggtttgt aacccaacga
     8701 tcacctcatt ctccttatca atatagcccg ggccatatac atcgatccct tgaggtaatt
     8761 ttgtctcggc gtcataaact cccttttccc tctcgacctt aaacatctcg gtcagcttgt
     8821 tccagaccct acgggtcttc tcggaagaag cgactaaaaa ggaatcatcc ccttcataag
     8881 gcgtatagtt actctggata aaatctctta cattgatctc tcttttccag gtctcacctt
     8941 taaagtgatc ccagcactca ttctcaaatt tcataaacaa tcttatctaa taccacattt
     9001 ttaccgccgc aaaggtagga gaattatcgt catatttctg tcacatatgc tacaccagtt
     9061 ctaaaatccc tataaattgc gataaaaaag cttctcatcc ttcactattt taaaaggaca
     9121 ttaccaataa atggggagtc agacctaagg gcgaagaggc aaccatgccc aaaaagtaga
     9181 tccgacacca agttttgaag taaagcccac ttctccccct gccgcttcta cgatagctct
     9241 ggagatcgtc aagccaagtc cggtaccctg cgagaactca ttcaatttct caaaacgggt
     9301 aaatactttg tcatgcaaat catccggtat accgattccc gtatcctcaa catagatacg
     9361 aagacctttc ctttcaatgc catatcccat tttaatatat ccggatttgg tgcattttac
     9421 cgcattagtg aggaaattca tccatacttg cttaagccgg tttctatcca gaagtaccca
     9481 gcactccgag ttgggaccat ctaaacgtaa ctcgacattc ggatttgtca tcttcgcctg
     9541 aatcgtaaca aataactcat tacaaacctt agccagattg aaattctcct tcctacgttc
     9601 aattatgcct gactctatct tggaaagatc aaggatatcg ttgatcaatc gcaataacaa
     9661 ctcattattg gattggatga tatttatata ttcttttttt tcttccggat catcacaagt
     9721 taccattaac tctgaaaaac caacaatagc gtttaacggg gtacgtatct cgtgactcat
     9781 attagcgaga aacgcagact tgagacgatc cgaaagttcc gctttctcct ttaattcctt
     9841 caattgctga atcatcttct cccacttcgt attattgatc gtaataccgg tatagcgagt
     9901 cacatggcct tctttatctc tttcaacctg gattccagta accaataagg tctgccactc
     9961 gtcatcccat ttggttttgg aacgatattt aacgttgaaa tctttatcta tgccccggaa
    10021 catatgctcc atatatttcc gcacaaaaac cacatcatcc ggatgtgtag cgttcaaata
    10081 atcctcggga gtgattgtct tttccgaata aaaatcatta ataggatcat taaaagcact
    10141 gaatttcagg ctttttacat caaaatccca atacgacata ccaaccgtct tgaaagaaag
    10201 ctctatcttg taatttcttt ctttaagttc ccgattcaat tgctggatct taggaatgtt
    10261 ttgcctgaat cccgtatagc gtattatatc tccattttca tcttgatcga aagggacacc
    10321 cataaaatca caatactgcc aagtctcatc atacttggtt tgtatgcgac aggtaaaatt
    10381 gatggtgaca ttctttccag ctatcaggga ttgcattgcg tcgtaaaaaa cagaccggtc
    10441 ctcggggtat ataacatcca tatactccga aacggtcaat aatcgatctg aaacgtaatc
    10501 gttgatcgga tcattataag attcgaattt ctgggaattt acatcaaaat cccaatgaac
    10561 aatattactg actttcatgg ccagatcacg ttttgcgatc agatcctgcg ctttcttggc
    10621 catttgcaac ctttcggtta tatccatttg tgtcccgatg atctgcaatt ttccacgatg
    10681 ttctgtcgat aggcgcatcc ggctctcata ataacgatac atctcttctt gctcgttata
    10741 gaaacgcaaa gtcatttgtc cttgttctat ctcatttcct atcaattgag agaagagccg
    10801 gattaacgga gctcgatctt ggggatgcaa aatatccagt accgcctcca ttggcatatt
    10861 ttttttggct acggttagtc catataatgg attaaaaacc tttttattca catcatatac
    10921 ccaagaagcc atattagccg ctttcatggc catctccaga tttttcttgc tttcttccgt
    10981 acggaattcc acctctttca cggaagtcat atcatttgcg agtaatatat gtccgataag
    11041 atgttttttt ctactccata tcgggataac tttaacccca tagatcatcg tgtctttatt
    11101 ataggaagaa taatatgcat ccttattaac ccgatcaaaa tcatactcaa actccaagga
    11161 aatatcttca cccgattgta tccgagctaa aagttctgaa tcaacaaatg gacttttgta
    11221 aagattgact atattcacca ccgatgtccg gtcatccaca ccatacatcc tcaacgcatg
    11281 gtcgtttata ctacgcagca caccatgtgc gtcataaatt tcaataccca ccggcagaca
    11341 agcatatata ctctccgtaa ataaacgctg ttcttctatt aatttagaaa tttctttctc
    11401 tattatcaca tcgtcatttt cttgagaatt ctcttcacat tgttccatct gtcacttact
    11461 ttatttcgta ttatcatacg tcagacattc taatttatac gaaagccctg ctttttgcaa
    11521 aagtaaacaa aaaagtgaat tcttttctgt tcgttcataa agatattatc tttgcgctga
    11581 aaacaaacac taaatcttaa atacatgaga ttcacaaggc ttattctagc gttaaccagt
    11641 ttccttatat tgatcacgca aacagaccta tttgcctcaa ccgtattgca taaaacttct
    11701 atggttgatc tctcaaataa cgctattatt tgcatgcatc aagatccgga tggctatttg
    11761 tggatcggga cttacgacgg acttaactta tacaacggaa aagatacgta tgtatatcgt
    11821 ttcgaattaa ataacaaaaa ctctctttgt agtaatatca ttcacaaaat atccgacgca
    11881 gaacccggct ttttatggat atcaacctct ttaggtatca ataaattctc actaaaagaa
    11941 cggaaagtca ccgagtcttt ccccggatac atggaatgcg atctattggc ctccgattca
    12001 tccggcatca cgctcgctat ttgtaaggaa aacagaatct cttgctacac cccatctagc
    12061 gatgggttcc gggacctgcc gagagaagga gtaggccctc aaaccgtacg taccttattc
    12121 gccgggacgg acggacattt ttatttatta ttagcctcgg gcatactgaa aaagttgact
    12181 ccggatttct ccgatactac ttttaatttg ctatcggaag aacgccaatt ccataataaa
    12241 ccgatcttat ccgcatttta cgagaataat catattttca tagtagatac cgacaataaa
    12301 ttatatcgac agcatgtaga cggaaagggg aaagaattcc tgttcgatct gcctgaaatg
    12361 acaaaacaat atggtaacat catcaagata tgcaccttcc aatccaatgt gtatatcgtt
    12421 ttccgtaacg gcaatattct agacctaagc caaccggaaa acacgataaa tatgggcatc
    12481 ggtatctttt gcctaatgaa cgataaaagg caggagattc tctggttggg aacagacggg
    12541 caaggtatac ggatgtttta tgacaaaccc gatcttttcg gctctatctt actcaaggat
    12601 ttaccgatta atatacagaa ccccatacgt tctttatata cagacgatga tcaatccctt
    12661 tggctcggga caaaaggaga cggtattgtc cggatacaag cgtatgacac ttaccataac
    12721 aaaaagatga tcccacaaag cgctatcacg cattttacca ccgccgacgg cctatccagc
    12781 aaccgtgtgt attgcttcca aaaaagcgag taccatccat gtatctggat tggcacggaa
    12841 ggcccgggac tgacctgtta ttcgtataaa gagaaacgaa taaaaacgat accgcaacga
    12901 gaagacacca cccctctacg ctatgtccac tctatttgcg aggtagatga ttccacatta
    12961 tggctagcga caacgggtaa cggattgcaa aaggttacct tacatataga taaagccgta
    13021 cctacaatcg ggaaggtaca aaccttcccg ttaaaaaacg gaaagaacat ctgtaaagaa
    13081 atccaatcga tggtatatga caacgactct accctgttcc tcgggagccg tggcggttac
    13141 ggagtcattc gtttcaatat tttcaatcaa ggatatgaat tcctgcaaac caacaattta
    13201 agaaacccgg ccattggaga tgtgctttcc gtatgccaga ccgaagattc cacgttttat
    13261 gcaggcgcca gctccggtct cacccggatt aaattcagag ggggaaagat gcgtttacgc
    13321 caattcgata aaagcgacgg gatcgtaaac gacatgatcc atggtatcca tgaggggaac
    13381 gatagctgta tctggcttag taccaataaa ggtctcacca aatataatcc ccggaacaac
    13441 tttttccata attatcatca gccttacttt agcgtcacgg aattctctga tgacgcttat
    13501 tggaaatgcc catactccga gcgtttattc tttggaggca tcaacggatt agtctgggta
    13561 aataaacaaa cggagccgga gcatacctat caacccgaat taagtttctt cgagttgcaa
    13621 atggataaac aaatccttcc attatataag gacatcagcc ggaacggtgt aacggttccg
    13681 gctgatgtgc aatcgttaac gattgcgttc gtcgctccgg attacatcaa cggggagaat
    13741 tacgagtatt cgtatcagtt ggtcaactat aattcctctt gggaaaaatt gcaaaagaca
    13801 aacaaggtaa ctttcatgaa cctaccgtac ggggaatatt tgctgaaagt ccgttatcgc
    13861 aacgatgtca ttgattcgtc agcaaaagaa tacactctac ctatcaaggt attacctcct
    13921 atttatctaa gctcgttagc cattttcacg tatcttttta tcggtacagt tttgctcatc
    13981 atcgccacct atcgtatcca tcaccaaata ctaaagaaac agaagcagat cgcagacaag
    14041 atcaaggagg agcaaaaaga gaagctatac gagtccaagc tgaatttctt tacccacatt
    14101 acgcatgagc tatgcacccc gcttaccttg atcaatggcg tggagaatta tatccaagcc
    14161 tatgccgcca cctcaaaaga caagacatta gaaaaataca cttcagtcct ccgggaaaat
    14221 gtagaggaac tgaacggact tatccaagaa atccttgatt tccgaaaagc ggaagacgca
    14281 ggattcagtc atacgcacat ccggagagta tccgtatcct ctcttttgcg aactcaattc
    14341 gaatggtttt acccactatc cgagcaacac caaatccaat tcaagatcga tgctcccaaa
    14401 gagctttatt ggaatacgga ttccgtctat ttcaagaaga tcctagcaaa tctgatttcc
    14461 aacgcattta agtatacgga agacgggggc acggttcgta tctccttaca tgaggaggag
    14521 aacttcctcg tccttaaagt ttacaacacc ggcaaaggaa tcgaggaggc agacatgcaa
    14581 aatattttcg accgatatcg tatccttggc acgatggata acgatgataa caggcaaaat
    14641 acgacacgga atggcctcgg cttatttatc tgtcacagcc tcgtacaatc cttaggtggt
    14701 aaaatcgaca tagagagtga ggtcggccaa tatgctgaat ttacagttac cttacctttt
    14761 ggcatcgtag aggagacctc agacaacacg atagacgaag agattcccgt atcgcttcct
    14821 tccccaaaca cggatataca agagccgcaa atctcacata cggcacaaaa agagacggaa
    14881 gataaaccga tgatactcgt tatcgacgat cataaagaca tcgtctggtt aatcacggaa
    14941 accctctctt ccgaatatca ggttcaagaa gcttataatg cggaaaaggc tctggaattc
    15001 ctcaaacaat acactccgtc ccttatcatc accgatatca tgatgcctaa tatggacgga
    15061 ttagaattga tctcgcttat caaagaaaat aaatataccc gccatatccc gcttattatc
    15121 atctctgcta aaatatcaga ccaagagcaa gcggcaggac ttaatatcgg agcggatgcc
    15181 tatctaacca agcctttctc gccaacagtt ctcctatccg tcgtgaatcg attgatgact
    15241 aaccaaagag aattaaaaga gtatttctat tctccggaaa gtgcttatca atatacggaa
    15301 gggcaattat tacatcaaga agacaaggaa ttccttgaca ccgtaacctc tatcatcaaa
    15361 gaaaatgtca gcaaggaagg actcggtccc gagctggtag cggacgcatt gaatataaac
    15421 actcgcatct tatatcgtcg tttcaagaaa atatctacta tgacgccgag tgattttata
    15481 aaggattata ggttaaacta tgcagcgcaa ttactcgtga ataccaacat gagcgttcag
    15541 gaaattattt ataatgtagg aatttctaac aaatcatact tctataggga atttgcccgt
    15601 aaatataaca tgacacctaa ggaataccgc acaaaagagg cataaatcat tgattcctaa
    15661 atagtgtcat aatctaccaa aagagtatca taatctgcta tatgcatttc atgacacttc
    15721 tttggcattt caaagcactc ttcaattcgt taagacctat taatattgct gtcgaatagc
    15781 aaagcaaacc gcttgtgtgt attcttcctt cgggaagcac attattaact tttaatttaa
    15841 tgtttttatg gaaaaaaaga gtgaaggtaa gacgaggaaa tgcctgactt tattaggtgg
    15901 acgaacctct ttgttacttt gtttatcttt aatgtttcag tcctcttatg cggccggaga
    15961 ttctactgtt cctgaaatgg gaaacatgga gattcatcag atcgcacagc aaagttcaac
    16021 cattaaaggt gtagtaaaag accaaaaggg tgaacctctg attggcgtta gtattgttgt
    16081 gaaaggaacc acgaacggaa cagcttcgga ctttgacgga aatttcacct tggatgtgcc
    16141 ggataacagc acattggtat tttccttcat cggcttcaaa ccccaagaag ttcgttatac
    16201 cgggcaaaaa acattgaaca tagtcttagc tgaagactct gagacactag acgaggtagt
    16261 agtcgttggc tacggttccc aaaagaaagg tgagatcacc tcatccgtta ccagcgtgaa
    16321 agcatccgac tttaacaagg caccggtagt gaacccgatg caattggtgg aaggacgtgt
    16381 agctggtctg actgtatcac gtggtagcac cgaccctaat ggcgaggtaa aagtacagat
    16441 gcgtggtgcc tcatctctga aaggtagcaa tgagcctctc gttattattg acggtatgcc
    16501 gggtaatatg acttctttga acgctatcgc acccgaggat atcgaggcga tcgacgtatt
    16561 gaaagacggt tccgcagccg ctatctacgg aacccggggt aataacggtg tgatcatcgt
    16621 ctccacgaga cgtccgcaag ccggaactac tcaagtggat tactcaggat atatcatgca
    16681 cgaggcggtt tataaacgac cggaaatctt aaatggagac gagttcgtcg cttatggcaa
    16741 agaaactaac aacgccaata tccgcgactt tggtggacgg gataaccatt acgacgcttt
    16801 attgaataag agtaatttca cccatgtaca caacttgacc gctacaggtg gtaatggtaa
    16861 gacaaactat cgcgcttctt taaattacaa aaagaatgat ggtatgatcc gtaacaccag
    16921 ccgtggaacg atcaatggct ctatcgccgt gaaccagcgt gcg
//
