LOCUS       c00108_gnlPro..         6063 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BOPDAFEH_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:48:52
            Original ID  :: gnl|Prokka|BOPDAFEH_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6063
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..213
                     /locus_tag="ctg108_1"
                     /transl_table=11
                     /translation="YQLAGGTDAIMDRGFFRHLKNIWLGLDVFNILDIKNVSSYYWITD
                     VYNVQYAVPNYLTGRQLNVRLIVDF"
     protocluster    1..6063
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[341:4869]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      342..4869
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..6063
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6063
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             342..752
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.8e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             789..2342
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_3"
                     /sec_met_domain="CT_Btheta (E-value: 6.7e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             2364..3251
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.9e-13, bitscore:
                     40.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADGQP
                     GRGTFHVNFVLDPSKENYIALYDADGKTLIDEVTIPAGQMADISYGRVIDGKDEWAQLK
                     KVTPSTNNLTLDSNEKIDNFKQNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGRLSISA
                     SKRNAQKAAGTTSVSVDAGQESGEIFAAIATALYEMSDDNHDIEHTVLTIHKVQRTYSP
                     WSSKLYGLRQTPHK"
     CDS             3273..3704
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-21, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIADVEVNGTPYQVKLEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVTRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             3709..4869
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_6"
                     /sec_met_domain="OAD_beta (E-value: 6.1e-154, bitscore:
                     501.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(4936..5082)
                     /locus_tag="ctg108_7"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEITPVPIE
                     QTN"
     CDS             complement(5151..5867)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_8"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.9e-28, bitscore:
                     88.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGIKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETAITSPNACFIDGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
ORIGIN
        1 tatcaattgg caggaggcac ggacgctatc atggacaggg gcttcttccg ccatttgaaa
       61 aacatttggc taggtctgga tgtatttaac atattagaca tcaaaaacgt tagttcctac
      121 tattggataa cagatgtata taatgtccaa tacgcagttc caaactatct gaccggacgt
      181 caattgaacg ttcgtctgat tgtcgatttt taataaaatg tatctttaaa cacatttact
      241 gggagataaa aacaaaaaat tatttcctca ttcataaaaa gtagtgtaca tttgcacaca
      301 atagaaacaa acatttacta aatctttaaa ttattattga catggaactt acacatatcg
      361 aacatttagg tatcgcagtg aagagtatcg aggcttgttt accctattat gaaggcgttc
      421 ttggattaaa atgctacaat atcgaagtag tagcagacca aaaagtaaaa accgcatttt
      481 tcaaggtagg acagactaag attgaattac tagagccgac cagcgaagat agcacgatcg
      541 caaaatttat cgagaaaaaa ggtgaaggta tccaccatat cgcattcgcg gtacctgatg
      601 tacaggcagc tttgaacgag gctgaggaaa aaggcgttaa attaatcgat aaagctcccc
      661 gtggtggcgc ggaaggcttg aacatcgctt tccttcaccc gaaatcaact tgcagcgtat
      721 tgacagagct ttgcatgccg ggcaacaaat aattaatccg ttcatttcta acaacaaatc
      781 aaaatacaat gagtaaccag cttgaaaaag taaaagagct catcgcactt cgtgagcaag
      841 ctcgcttagg tggaggagag aaaagaatcg aatcacagca caaaaaaggc aaatataccg
      901 ctcgtgagcg tatcgccatg ttgcttgacg aaggtagttt cgaggaattc gacatgtttg
      961 ttcaacaccg ttgtacaaac ttcggtatcg agaaaactaa atatttaggc gatggtatcg
     1021 taacaggtta tggtacgatc gacggacgtt tggtatatat cttcgctcaa gatttcaccg
     1081 tattcggtgg agccttgtct gaggctttgg ctatgaagat ctgtaaagta atggatcaag
     1141 ccatgaagat gggcgctccc gttatcggtt tgaacgactc cggtggagct cgtatccaag
     1201 aaggagtaaa tgccttggca ggatacgctg agattttcca acgtaacatc ttggcttccg
     1261 gtgttgttcc tcagatttcc ggtatcttcg gcccttgcgc cggtggagcc gtttattctc
     1321 cggctttgac agacttcaac atcatgacac gtggtaccag ctatatgttc ttgactggtc
     1381 cgaaagtcgt aaaaaccgta acaggtgagg atgtaaccca agagcagttg ggtggagcca
     1441 gcgtacacac taccaaatcg ggtgtagccc atttcgctgt cgatacagaa gaagatggtt
     1501 tgcaattgat tcgtaaattg ctcagtttct tacctcagaa caacttagag gaaacgccgt
     1561 tagttgagtg caaagacccg atcgatcgtc tggatgatgt attgaacgat atcattcccg
     1621 ataacgccaa ccaatcttac gatatgtatg aggttatcgg tacgatcgtc gataacaacg
     1681 agttcctaga ggtccatgcg gactacgcta agaatatcat cgtaggtttc gctcgtttca
     1741 acggacaatc cgtcggtatc gtagctaacc agccgaaggt tatggcagga tgcttggata
     1801 gcaacgcatc tcgtaaagca ggtcgcttcg ttcgtttctg cgatgcattc aatattcctt
     1861 tggtaacatt ggttgacgtt ccgggattcc ttccgggcac aggtcaggaa tacaacggtg
     1921 taatccttca cggcgctaaa ttgctttacg cttatggtga ggctaccgtt cctaagatta
     1981 ccgttacatt gcgtaagtct tacggtggag cttattgcgt gatgagttct aaacatttac
     2041 gtggtgatat gaattacgca tggccgacag ccgagatcgc cgttatgggc ccgagcggtg
     2101 ccgtagaggt tatcttcgcc aaggaagtag cagccgctga agatccgaaa gcatgcgcag
     2161 cagagaaaga agctgaatat aagaaagcat tcgctaatcc ttataacgca gctcaatacg
     2221 gttatatcga cgatgttatc gaaccgcgta acactcgttt ccgtattatt cgtgctttgc
     2281 agcaattgca gactaagaag ttaagcaatc ctgctaagaa acatgataac ctgcctctat
     2341 aatccgtaaa acaggagatg aatatgataa ataagaaaat aggggtattg ctactgttcg
     2401 ctttgctcat ttcattcggg gcaaaggcac agcgcgcaac ctccatgcgt attaatgaag
     2461 tattggttat caacgaggat aacttcgttg acgactatgg caaacgtcat ggctggattg
     2521 agttgttcaa cacttcggcc ggaacggtaa atatcgcggg atgttatttg acagacgaca
     2581 aaaacaatcc gatgaaatat ccgatcccga agggagacgt attgactcag atccaacccc
     2641 gccagcacac actattttgg gctgacggac agccgggcag aggtacattc cacgttaact
     2701 tcgtattaga tccctctaag gagaattata tagctctgta tgatgcagat ggtaaaacat
     2761 tgatcgacga agttacgatc cctgccggac aaatggctga tatcagttac ggtagagtga
     2821 tcgatggtaa agatgaatgg gcacagctga agaaagttac tcccagtacg aataacctaa
     2881 cattggattc taatgagaaa atcgataatt tcaaacagaa tgactcttta ggtatcggta
     2941 tgaccattac cgctatggct gtagtgttct tgggattatt tttgttatac atcatcttta
     3001 agcagatcgg tagattgtct atatccgcga gcaaacgtaa cgctcaaaaa gctgcgggaa
     3061 caacaagtgt atcggttgac gccggacaag agtctggtga gatctttgcc gctatcgcta
     3121 ccgctttgta cgagatgagt gatgacaatc atgacatcga gcacacggtt cttacgatcc
     3181 acaaggtaca aaggacttat tctccttgga gttcaaaact ctacggtttg cgtcaaaccc
     3241 cacataagta attatctaaa aacgaacaaa gaatgaaaag ttttaaatat actattaacg
     3301 gtaacgtata taaagtacac atcaattctg tagtggatga catcgcagat gttgaagtaa
     3361 atggtacacc ttatcaagta aaattagaga aaccggcgaa gaaacaaatg gttacattga
     3421 aacgtccggc tcaagcaccg acaacagcaa gtggcgaccc tgtagttact cgtccggcag
     3481 cctctactac acaaggtgct gttaagactc cgctgccagg tgttatcttg caggttaagt
     3541 gcaacgtagg tgataccgtg aagagaggtc aaacattgat tatccttgag gctatgaaga
     3601 tggagaacaa catcaacgca gaccgtgacg gtaagattat agaaattaaa gtacacaagg
     3661 gagactctgt gctagaaggt gctgatctcg tagtaatcgg ataagactat gcaagagagc
     3721 tttttaacat tcttaggtga gaacttacaa ctgttcctta cctatacagg tgtatacaac
     3781 gctactccgg gacatctcat catgattctg gtaggtctgt tgtttatatt cctggcgatt
     3841 aaatatgagt ttgaaccgat gcttttgatc cctatcggat ttggtatctt gatcggtaat
     3901 atccctttca aggacgcagg tcttcaggta ggtatttatg agcaagggtc tgtactgaac
     3961 atcctctatc agggtgtgac ttctggatgg tatccgccat tgatcttcct cggtatcggg
     4021 gccatgaccg acttctccgc attgatctcc aatcctaagt tgatgttgat cggtgcagcg
     4081 gctcagttcg gtatctttgg tgcttatacg attgctcttc aaatgggatt tgagccgaac
     4141 caagcaggtg ctatcggtat tatcggtggt gctgacggtc cgacggctat cttcctgtct
     4201 tctaagttag cgccaaactt aatgggtgcg atcgcggtat ccgcttactc atacatggcg
     4261 ttggttccta ttatccaacc gccgttcatg agattgctta cgactaagaa agagcgtttg
     4321 atccgtatga aaccgccgag agccgtttct tccacggaaa aaattatctt cccgatcgtt
     4381 ggtttgttgc ttacttgctt cttggttccg tccggtttac cattgttagg tatgctattc
     4441 ttcggaaact tattgaaaga aagtggcgtg actcgtcgtt tggcagagac tgctcgtggt
     4501 ccgctgatcg atacaatcac gatcttattg ggtatcacgg taggtgcttc tacccaagct
     4561 acacagttct tgacattgaa ctctatcaag atcttcggtc taggtgcgtt atcattcgtg
     4621 atcgctactt gcgccggtgt attgttcgtt aagttattca atttaatatt gaaagacggc
     4681 aataagatca atccgcttat cggtaacgcc ggtgtatccg ccgttcctga ctcagctcgt
     4741 atctcacaag ttgtaggttt ggaatatgac ccgaccaact acttgttgat gcacgctatg
     4801 ggtccgaacg tagcaggtgt aatcggttcc gctgtagctg ccggtatctt gctaggattc
     4861 cttggttaat aaaacaacta tctatattaa aaaaggcgag gtccgaaagg atcccgcctt
     4921 tttatgttat tgttctcagt tagtttgctc tataggaacc ggagtaatct ccgtactcgt
     4981 atcctccacc aacgttgtcc cgaggaacaa ccagatcatc aaaaggatta tagcgacaac
     5041 cacaccaaat accaatagcg tattcacact tttctttctc atgtctttaa ctgatttatt
     5101 cattttagaa taaacagccg gaacatgaat ttggttgtgt acccttactc ttatttgttt
     5161 ttccctaacg cctcgttcag cactttgttc ttagcgatcg ttgcttggaa ttctttcaaa
     5221 tagaaaggct caaaataagc cacattctca aaacggccat catcatatgc tttctgcgac
     5281 aaggatgcca tatttacagc taatggatag ataccatcta taaaacaggc gttcggagaa
     5341 gtgattgccg tctcacattt agcggcaccg tctccaaaga aacaaacctt accgttctct
     5401 aaaaaagaag catacgaatc agcatctacg atatcagcag tcgtggcacg tatcgtgttg
     5461 agatgggaat cataaatcga agagtagact tccatacgac gggcatccaa catagcgcaa
     5521 tacaagcaat cggcctcctc cttatttttc cggatagcgg cagacgctaa aatatccagc
     5581 gtatgaatac cgatcaaagg aataccatac ccaaagcata atcctttagc cacagacacc
     5641 ccgatgcgta accccgtata agatccgggt ccgctactta ccgccacggc atccagtttt
     5701 atccctttcg acttcgcggc ttctaatgcc tcttccatat aaacgcccaa taacgccgca
     5761 tgagacggcc cctcgaagga agccttctca aagaccacct cctccccttc cgacagggct
     5821 actgaacata cggaagtgga tgtctcgata tttaagatca atgacataat aattaactat
     5881 taacaattga taattgaacg aacaaacaat ctcaaacctt caatctgatt aggctacgaa
     5941 ggtatacaaa aattcattat actatcaagg cagccctatg agaaacatct atttatgaga
     6001 aaataaacat caaatctaaa aggaaaccac tatctttgcg caaacttttg agaaaaatga
     6061 tac
//
