LOCUS       gnlProkkaJKGOOGPF_4    16220 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKGOOGPF_4.
ACCESSION   gnlProkkaJKGOOGPF_4
VERSION     gnlProkkaJKGOOGPF_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 20:21:49
            Original ID  :: gnl|Prokka|JKGOOGPF_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16220
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16220
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[4501:6220]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4502..6220
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..16220
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16220
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             110..835
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MEMLYNNRVTICTCASRSFIDKEKVVKVAAFLRQEGYDVVVEPDL
                     CEKVRERTSDLPDVASSTIIACYPRAIRSLFASVGMETSRVLDIRNEGMEAILDSFGFA
                     YEVSPVEMEEEEVIRQSVSSFPVKIGVDAWYPTLDKERCTDCGKCHDFCLFGVYTIEDG
                     VVTVKQPQNCKNNCPACARMCPNKAIIFPKYEKSPINGGLKDEELAVSIDAKTVYADTL
                     RARLAQRRAGVSFLKKDNQ"
     CDS             832..2049
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="PF04055 (E-value: 7.3e-15, bitscore: 45.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFNEYIATARTSSRIFKECSPRLIWKFMYNFGWRNFRNMAAFEK
                     RQALGAPFFPAFVMISITESCNLSCSGCWVSAGGRKALSIAQLNGIITESKRQGSYFFG
                     ILGGEPLMYKGLLETMEKHSDCYFQLFTNATLLTEEVAFRLKKMGNVTPLISIEGLKDE
                     SDIRRGKDGVLDRTIRGVRACRKARLIFGVAASICRSNYEDLVSRAHIERMAREGALYL
                     WYYIYRPVGAVPNVENALTKEQIRDFRRFIVEQRRDAPLFIIDTYWDDKGKALCPAATG
                     MSHHISPSGAVEFCPPLQMARDFINGDASNLVELFRDSRFLADLRKMTAETSRGCILLE
                     DPGKMWRFLEQQGAIDTTTRGTVREEYQKMNPVPGHDMEGEEIPEQNVFYRLLKKKYFF
                     GFGAYG"
     CDS             2063..3619
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 142.4; E-value:
                     2.6e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MENKLIHNIPASYAERDELRNRIQAFVDDLTIQPPLSLDDLSNFA
                     DQLIREYALDVEVRGWLMVEIHNQVWKETVASIPYERRVLLLPKCLSNSAKCQAEIDEL
                     GLLCHRCSHCSIPDLQDKAESLGIMSIVAEGFTSVVGLIQNRVVDSVIGVSCLDSLEKA
                     FPLLISNAVPGLAIPLNTSGCKDTHVDYEYVVRMMGMRSDNEARLLDYDGLRADLKRWF
                     SKENLAGHFSPAKDQTSSVALEWMGGEGKRWRPYLLAATYLALTGGAEVPDDVQRAAIA
                     VECFHKASLVHDDIQDNDKERYGKPTINALYGVPIAINVGDILLGEGYRLLSQCDARAL
                     TAVAADAHIALCKGQGMELEWSVSPRPLTLDWVLEIFCNKTVPAFEVSLVLGLICAGDD
                     ELLRRIFHQYSRALGIAYQLLDDIEDFKDDRPVALRPSAVLAVLCEQNPEPVFTRSLLE
                     CENLKAFLGCSENKPLLRTALERVGQMADTYHQAALTALHEIKNVELKRLLFRVTERIL
                     K"
     CDS             3633..4505
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MKTTISTRLMHTLYGGKKRLGSEALLRLSCFVESQKTEGDTFVNK
                     SGEVDLYYTSFGWLLSYVLGIDLSMEKRRSYLEKQPVMSLDLVHYAAYMRCVLLHRLMK
                     EGKFRFLLGAMRPMPIRSLTSFMDLPHDDIWSPYTRFIWMSLLEDTQNKENEKKAVLEK
                     LRSYRVKGGGYSNLRDREVATTNATVAALAIIGQLEGYKPIDDLFYLRDTQDETGGFKA
                     GRGAPVPDLLSTATTLFLMGCYDIRPVRPVHDFIEAHWLDSGGFSATLLEDSSDVEYVF
                     YGLLALGAL"
     CDS             4502..6220
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="terpene_cyclase (E-value: 1.9e-44,
                     bitscore: 142.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTEQVNEMIADITRQLLQKRSSDGIWRGCLSSSAISTSVAIFAL
                     YQIDSDTYEPYIRKGAGWLKKTMRADGSWGDSVESPSNMTATLLSYASLYAVDILPHET
                     ETYLKERLGGNTDEDIVQGVLSYYGKDLTFSVPILVMCALAGVITHWDRIPQLPFELSV
                     LPQRLFRFLRLPVVSYAIPALIAVGILRYKKGKRDFLSSVRESFIGKSLRVLEKLQPSH
                     GGFLEAAPLTAFVSMCMSGAGFREHAVTQKAAQFLIKTVRPDGAWPIDTDLSCWVTSLS
                     IKVLGEDLEDKTFFIERIKRNAFAFRHPFTGAKEGGWGWSDLPGSVPDADDTSGALVAL
                     HVLTGGTYSEEVGKGVEWLLALQNEDGGMPTFCKGWGKLPFDRSSPDISAHSLLAFELW
                     LDALPKELRVKCRRSIRRLLGWMWKIQSSDGSWTPLWFGDQDAKDERSPVYGTAMAVEY
                     LSTSRNPLARKLAENGLRYLLASQNEDGGWGGAPRVASKITLTARALSALASYPESDLK
                     SMERGFDYLYGMYQSGLLFRPEPIGLYFARLWYSEELYNHTFVLNALKKLKQRIK"
     CDS             6229..7650
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MKERKTLLITVATVCIYTAILVGWHLYVPRENLTIQVPGADNRPE
                     GLARKANDVVIGEYFMKYEEEPPSGLTGEWTGFRGERFDNVVETPDKINTEAGDYPVVW
                     SFETGEGHAAPVIYKGRVYVLDYNESLNSDALRCFSLESGKELWRRWYRVPMKRNHGFS
                     RTVPVIRDEYVITIGPQGHVMCCDPVTGDLKWGIDMQKQFKTEVPFWYTGQCPCVDDDV
                     LVLAPAGEETLLAGVDCLTGEIVWSTPNTLGYKMSHSSVMPMSLSNKRTYVYAGVGGVC
                     GVSAEKADRGTLLWDTKKWQPSVIAPSPLRLSSSRIFLVAGYGTGGALLQVDKAGSKWT
                     ATVLDQYKADKGLSSEQQTPILYNDMIISVMPKDGGGLRSKLVCFSPTDLHNPIWSSAA
                     DERFGLGPYLVINKHLFVFKDDGELYVYEIQSKAMKLLKKQRVMDGVDAWGPMAYADGM
                     LVLRDAHTVKCLKIV"
     CDS             7690..8733
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MEPNQDNGNRISRKSFLRICGSVIAGGSILGVTGNLLWKMFTRPD
                     DIFYGVDKKSTTINRSHVNNIVSPYRKVSAFKISDQIDAFDLYEGRLIVAAPNNIYVYE
                     PSGALVSNFPVGSSVRDVTVDDDRVYLLYPTRVEVYDLEGGWIRDWEACSEESDYCSLT
                     VLSGNVFVTDAANKNICMYTIEGGFVKFIQSPSGFIVPSYSFGITNIDGVVYCSNPGRH
                     LVESYSPEGEYISSFGKPGGAAGLFSGCCNPVYLAGTPTGEIITSEKGIPRISCYGKNG
                     EFHSVLLDEKALGGGHAAYEVRVWDDKLVVAGKDALSIFQYDKKLAVQTACSTCGIDCP
                     LKIGVTI"
     CDS             8742..9317
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MEQKKDHPKNSPIKRREFFKLCGSVVAGGTILAVAGGMARKVEGT
                     EASLFWQIDPNVCTQCGRCETHCVLPVSAVKCIHANKVCGYCDLCGGYYRTNVKELNTA
                     AENMMCPTGAILRKFVEDPYFEYTIDEDLCNGCGKCVKGCSSFGNGSLYLQIKQDLCLN
                     CNECQISTVCASGAITRVPYVTAYKLKG"
     CDS             9322..10605
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MKKLLSIGTLLFLWVMLQAQNRFPKPDFESGYQYPELHYAIPNET
                     LWVVLDLFMLVLLMSIVVWAVYKKHTRKPIFWVSVISVAYFGFFRSGCVCSIGSIQNIA
                     LAMVDSTYHLPLTVLLFFILPILFAFLFGRVFCAGVCPFGALQELVNVKNYRISKAVTA
                     ALGIIPWLYLIFAVLYAVTRSRFIICQFDPFIGIFRLGGDVGLLLFGALLLILSVFTGR
                     PFCRFLCPYGALLSLFSSVSIWKIRLSRKECINCELCHNSCPVDAIRSPYANKVKESRK
                     EGVRRLLGYLVVLPLMIAAGAFLMRSASSDLSRANKDVRLYDMVERHEANPEEELSLEL
                     EAFYGQGRTLEELTSAYEAKLDEFRFYSTIAGGLIGLVIGLALIRLSVKRTRKQYEINH
                     AACVACALCFSYCPQNKNSVELRKSSES"
     CDS             10602..12398
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MNKDIYRNIAAVTAIFIISLSVMLITNYFQVRGVTPLQTEVVETL
                     KLLNDTNPDNPELQEQIRQLDLLARRAYFIQADHLKLGVYILLGMVAVFVVCLRFYFKG
                     EMHIPDKEIDPIDEWMLKSKSRKYITWSMFGLVGVSLFFVFLSSPFLATEKTESVAEET
                     LIAESTQVEPDSEVIEPAIDIEEPMNEVIIDTTNDVTPVEEAFPATSEEPQPVVPKITH
                     NAFRGNYSNGVSAAKGIPVKWDLGSGTNIAWKKEIPRPGHNSPIINGNHVFFTGADEQA
                     RELYCYDLTTGEQRWSLAATNIPGSPSVMPKVTEDTGLASSSVATDGNRVCAIFATGDV
                     VCADMDGKQLWAKNLGVPDNHYGFVSSLLIFGNTLFIQYDNNKDPKLIALDVANGNQRW
                     VKNRPGKICWSSPSIAYVNRKPQLILMGNPAITAYDPNSGEQLWQVDCMGGEVCSCPCS
                     IDGVIFGANEYAKLVAINGADGKVLWESSDYLPEVSSPVATKDHLYVATSYGVLAAYDT
                     KTGALAKEHELNVEFYSSPMIVEGKLYLFSNDGKMHIFSTDNEFNLLSSFETGERTMAT
                     PAFTDGKIVVRTEKSIYCVAMN"
     CDS             12400..14790
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MACDNCKNNGIRTKEAMTARVDAIIDRIGTSRRDIIPLLQALQDE
                     FSYLPSDALLRVYERTEIDRAQLISVSTFYSQFRHVPYGKHIIKVCTGTACHVKGANNV
                     YDAFRRELKMEEDRITTADQEYSIEKIACLGCCALAPVVQIDEKIYGHVQPGRVNEVLD
                     EFRIYNQEHEREEEGNATRQIVGEIRLGMENCCQASGTSEIYQAVIKASDELGIEVNIK
                     PVSCVGACNQVPLIDVAHPDGSIERYPNVRPEEIKEILLHHFQPASRLRRLKNSILNHI
                     DMFHTDTTWDNILWKSEQERTGAINTFLSGQKRVSTEGYGLMSPLDIDEYIARGGFEAL
                     KKAITSKSRQEIIDTILRSGLRGRGGGGFLTGRKWELVAASDQPEKYVICNGDEGDPGA
                     FMDRILLESYPLRVIEGMIIAGYAVGAKEGIFYIRAEYPQAVIRTRKAIELCRERNWVG
                     DHIFGSDFSFEISIFEGAGAFVCGEETALIASIEGERGFPRQRPPYPAVEGLNKRPTLI
                     NNVETLSQVSYIVNHGVDEYRKIGTENSKGTKVFALAGKVRHGGLIEVPMGTTLNQIIE
                     DIGGGVEGGEKLRAVQIGGPSGGCIPAHLCDAKVDFDALTQMGAIMGSGGMVVLSESNC
                     MVDVARYFLAFTCNESCGKCTFCRVGIRRMLDILDKLCTGKAEMADIDKLEELALSVKK
                     AALCGLGKTAPNPVLATLKYFREEYEEHVRGICRTGTCKDMVRLMITDDCVGCTKCSKA
                     CPSDAIPYTPYEKHSIDIEKCVLCGLCIDECSFDAIRKVSLKS"
     CDS             14798..15763
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_12"
                     /sec_met_domain="Fer2_4 (E-value: 2e-16, bitscore: 50.0,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITINNKEIEVLEGETLIEVARRAGFRVPSMCYAKEAKHKSSCMV
                     CVVRNSVSGQMIPSCSTYPVEGMRIETDSEEVSRLRALSLELLLSDHRADCEAPCTLVC
                     TQGLDVERMLYLYDAGRYGEARSLLAAVFPLPAVGCDTCKAPCEKACRRGTVDKAVEIR
                     AIIKELAGRVDLPVEDDYHVADKRDKNVFISRLGRFTMKEKEWLKETTSAPSGCLHCAC
                     GGKVDCKLRLYATEAGIKRPRYEVSSMLPVKEKIHVKGRMWFEPAKCIRCGLCVYNSEN
                     GFTFKNRGFGMQVVIPKESKTNVKEELAGLCPTGALYLVD"
ORIGIN
        1 gaaatcgcct tttttcgtga taagtactca atttttcgcc ttgcgccgga tgctgtacta
       61 gtgtttggat attgtttgta atattgcgaa agacgaataa taatacttga tggaaatgct
      121 atataataat agagttacga tttgtacttg tgcctcccgc tcttttatag ataaggagaa
      181 agtggtaaag gtggcggcct ttttaaggca agaaggatat gatgtggtag tagagcctga
      241 tctatgtgag aaagtgaggg agagaacatc ggatttgccg gatgtcgcct catccacgat
      301 tatcgcttgc tatccgaggg cgatccgttc ccttttcgct tccgtgggaa tggaaacttc
      361 tcgtgtattg gatatccgga atgagggtat ggaagcgatt ttggattctt tcggattcgc
      421 atatgaggtt agtcccgtag aaatggagga agaggaggtt attcgccagt cggtatcttc
      481 ttttccggtc aagattggtg tcgatgcttg gtatcctaca ttggataaag aacgttgtac
      541 ggactgcggt aaatgccatg acttctgcct gttcggtgtt tatacgatag aagacggtgt
      601 cgtaactgta aaacagcccc agaattgtaa gaataattgt ccggcttgtg cccggatgtg
      661 cccgaataaa gcgattatat ttcccaaata tgagaaatct ccgatcaatg ggggtttgaa
      721 ggatgaggaa ttggcggttt ccatcgatgc gaaaacggtt tatgcggata cacttcgggc
      781 acgtttggca caacgaagag ccggtgtctc tttcttgaaa aaagataatc aatgagattt
      841 aacgaataca tagcgactgc aaggacctct tcacggatat tcaaggaatg ttcgcctcgt
      901 ctgatatgga agttcatgta caatttcggt tggcgtaatt ttcggaacat ggccgcattt
      961 gagaagcgac aagcattagg cgctccgttt ttccccgcat tcgtgatgat atccatcacg
     1021 gagagttgta atttgagttg tagcggttgt tgggtctctg ccggtggcag gaaagccctc
     1081 tctatagccc aattgaatgg tattataacc gaaagtaaaa gacaaggttc ttattttttc
     1141 gggatactgg gaggagagcc tttgatgtat aaaggtctgt tggaaaccat ggagaaacat
     1201 tcggactgct acttccaatt gtttaccaac gctactttgc tgacagaaga ggtggccttt
     1261 cgcttaaaaa agatgggaaa tgttactcct ctgatcagta tcgaaggatt gaaagacgag
     1321 agcgatatcc gccgtgggaa agatggcgta ttggatcgta cgatccgtgg agtgcgtgcc
     1381 tgtcggaaag cccgtttgat tttcggtgta gctgccagta tatgccggag taattatgag
     1441 gatttggtga gtcgggccca tatcgaacgg atggctaggg agggtgcgct ctatttgtgg
     1501 tattatatct atcgtccggt gggagcggtt cctaatgtgg agaatgcgtt gactaaggag
     1561 caaattaggg atttccgtcg gtttattgtc gagcaacgga gggatgcgcc cttgtttatt
     1621 atcgatactt attgggatga taagggaaaa gccctatgtc cggcggcgac gggtatgagt
     1681 catcatatat ctccgtcggg ggcggtcgag ttttgcccgc ctttacagat ggctagggac
     1741 tttattaatg gggatgcctc aaacttggtg gagctattcc gtgattcaag gtttttggcg
     1801 gatctgcgga aaatgacagc cgagacatcc aggggctgta tccttttgga agatcccgga
     1861 aaaatgtgga gattcttgga acaacagggt gcgatagata ctacgactcg gggtacggta
     1921 agggaggaat atcagaaaat gaacccggtt cccggtcatg atatggaagg ggaggagatt
     1981 cccgagcaga atgtttttta cagactcttg aagaagaaat acttttttgg atttggagct
     2041 tacggttaat ctttgagtac gcatggaaaa caaactgata cataacatac cggcatctta
     2101 tgctgaacgg gatgaattgc gtaatcgaat tcaagcattt gtggacgatt taacgatcca
     2161 gcccccactg tccttggacg atttgtcgaa cttcgcggat caattgattc gtgagtatgc
     2221 actagacgta gaggtaagag ggtggctgat ggtagagatc cataatcaag tatggaagga
     2281 aacggtcgct tccattccct atgagagacg tgtattacta ctacctaagt gtttgagtaa
     2341 ttctgctaaa tgccaggcgg aaattgatga attaggtctt ttatgccatc gatgtagtca
     2401 ttgttcgatt cccgatcttc aagataaagc ggaaagtctg ggcataatga gtattgtcgc
     2461 ggaaggtttt acttccgtgg taggcttgat acagaatcgg gtagttgatt cagtgatcgg
     2521 ggtaagttgc ttggattcct tagaaaaagc ttttcccttg cttatcagta atgctgttcc
     2581 gggcttggct atacccctaa atacgtccgg atgtaaggat acccatgttg attatgaata
     2641 tgtggttcgt atgatgggga tgcgctcgga taatgaggct aggctgttgg attatgatgg
     2701 attacgagcg gatttgaaaa gatggttctc gaaagagaat ttagcaggcc atttctctcc
     2761 ggctaaagac caaacctctt cggtcgcctt agaatggatg ggcggtgaag gcaagcgatg
     2821 gcgtccttat ttattggcgg ctacttatct ggctttgacc gggggggctg aggttccgga
     2881 cgatgtacag cgggccgcta ttgcggtgga atgtttccat aaagcctctt tagtgcatga
     2941 tgacatacaa gataatgata aggagcggta cggtaaacca acgataaatg ctttgtatgg
     3001 tgtgcctata gcgattaatg tcggtgatat cttattgggt gaaggctatc ggcttttatc
     3061 tcagtgtgat gcgagagcac taacagcggt ggctgctgat gcgcatatag cgctttgtaa
     3121 aggacaagga atggaactgg aatggagcgt ttcccctcgc cctttgacat tggattgggt
     3181 attggaaata ttctgtaata agacagtccc tgccttcgag gtatccttgg tattaggatt
     3241 gatctgcgca ggtgatgacg agctgcttcg tcggatcttt catcagtatt cccgggcatt
     3301 gggtattgcg tatcagttat tggatgatat agaggatttt aaggatgacc ggccggtagc
     3361 gttaaggccc tctgccgtat tagccgtgct ttgtgagcaa aatccggaac ctgtatttac
     3421 gcgttccctt ttggaatgtg agaatttgaa ggctttctta ggctgttcgg agaataagcc
     3481 gcttttgcga acggctcttg aacgggtcgg gcagatggca gatacatatc atcaagctgc
     3541 gttgacagct ttgcatgaga tcaagaatgt ggagttaaaa cgacttcttt tccgggtaac
     3601 cgaacgaatc ttgaaataaa tgactgtttg agatgaaaac tacgatatca acaagattga
     3661 tgcataccct ttacggaggg aaaaagcggt tgggaagtga ggctcttctg cgtttatcgt
     3721 gctttgtcga atcccagaag accgaggggg atactttcgt aaacaaaagt ggagaggttg
     3781 atttgtacta tacttcgttc ggctggcttc tgtcatacgt attgggcatt gatttgagta
     3841 tggagaaaag gagatcttat ttggaaaagc agcctgtaat gtcgttggat ttggttcatt
     3901 acgcagccta tatgcgttgt gtattgctac atcggttgat gaaagaggga aagttccgtt
     3961 ttctattggg ggcaatgcgt ccgatgccga ttaggagtct tacttctttt atggacctgc
     4021 ctcatgatga catatggtct ccttataccc ggtttatttg gatgtcttta ttggaagata
     4081 cacaaaataa ggaaaacgaa aaaaaggctg tcttggaaaa gctaaggtct tatcgtgtaa
     4141 aaggaggagg ctactcgaat ttgcgggatc gggaggtcgc tacgacaaac gctacggtcg
     4201 cagcccttgc gattatcggg caattggagg gctataagcc gatcgacgat cttttttatt
     4261 tacgggatac gcaggatgag accggtggtt tcaaagctgg acgaggagct cctgttccgg
     4321 atcttctttc tacggctacg accctttttc ttatgggatg ctatgatata cgacccgtta
     4381 ggccagttca tgattttatt gaggctcatt ggttggattc gggtggtttc tcggcgacac
     4441 tgctggaaga tagtagtgat gtggagtatg tgttttatgg attattggca ttaggagcgt
     4501 tatgagaaca gaacaggtaa atgaaatgat agcggacatt acccggcaac ttttacagaa
     4561 acggtcgtcc gatggaatct ggagggggtg tttatcttca agcgcaatct cgacatctgt
     4621 cgctattttt gctttatatc aaatcgactc ggatacgtat gagccatata taaggaaggg
     4681 agctggatgg ttgaagaaaa cgatgcgtgc ggatggttct tggggggata gcgtggaaag
     4741 cccttctaat atgacagcta ccctgctttc gtatgcttct ttatatgcgg tggatatact
     4801 gcctcatgag acagaaacct atttgaagga acgtttagga gggaatacgg atgaggatat
     4861 cgtacagggg gttctctctt attatggaaa agacttgact ttctccgttc ctattttagt
     4921 tatgtgtgcg ttggcgggag ttattacaca ttgggatcgt atcccgcaat tgcctttcga
     4981 gctttccgtg ttacctcaac ggctgtttcg ctttctgcga ttaccggtcg ttagttatgc
     5041 gatacctgcc ttaatagcgg tgggaatcct tcgttataaa aagggaaaac gggatttttt
     5101 atcatctgtt cgggagtcgt ttatagggaa atccttacgt gtattagaga agttgcaacc
     5161 cagtcatggt ggttttctgg aagctgcccc attgaccgct tttgttagta tgtgtatgag
     5221 tggggccggt ttccgggaac atgcggtaac acaaaaggcc gctcagttct tgataaaaac
     5281 ggttcgtccg gatggcgctt ggccgattga tacggatttg tcttgctggg ttacctcttt
     5341 aagtataaaa gtattagggg aagacttgga ggataaaact ttttttattg aacggataaa
     5401 gcggaatgct tttgccttta ggcatccttt tacgggtgcc aaggaaggtg gttggggatg
     5461 gagtgatctt cccgggtctg tgcctgacgc agatgatact tccggtgcgc tggtcgcttt
     5521 gcatgtctta actggcggga cttatagcga ggaagtaggt aaaggtgtgg agtggctttt
     5581 agctttgcaa aatgaggatg ggggaatgcc tactttttgt aaaggttggg gaaaactccc
     5641 tttcgaccgg agtagtcccg atatctctgc gcattcactt ttggctttcg agctttggct
     5701 ggatgcgctc cctaaggaat tgagggttaa atgccggagg agtatccgtc ggttattggg
     5761 ttggatgtgg aagattcagt catcggatgg ttcatggact cctttatggt ttggagacca
     5821 agatgcgaag gatgagcgtt ctcctgttta tggtacggcg atggcggtgg aatatttgtc
     5881 gacttcccgg aatccattgg ctcggaagtt ggcggagaat ggtctccggt atcttttagc
     5941 ttctcagaat gaggatgggg gatggggagg tgctcccagg gttgcctcaa aaatcacttt
     6001 gacagcccgt gcgttaagtg ccttggcttc ttatcctgaa agtgatctta aatcgatgga
     6061 acgaggcttt gattatttat atggtatgta tcaaagcggg ctattgttcc gtcccgaacc
     6121 tatagggctt tattttgccc gtctttggta ttcggaggaa ttgtataatc acacatttgt
     6181 gctgaatgcg ctgaagaagt tgaaacaacg aataaaataa gatagatcgt gaaagagaga
     6241 aagaccttat taataacggt tgctacggta tgtatttata ccgctatcct tgtagggtgg
     6301 catttgtatg tccctcgtga gaatcttacg attcaggttc ccggagcaga taatcgcccg
     6361 gagggattgg ctcgtaaagc gaatgatgtc gtgatcggtg aatatttcat gaaatatgag
     6421 gaggagcctc cttccggact tacgggggaa tggactggat ttagagggga gcgttttgat
     6481 aatgtagttg agactccgga caagatcaat accgaggcgg gagattaccc cgtagtatgg
     6541 agctttgaga caggtgaagg acatgcggcc cctgtgatct ataagggcag ggtatatgta
     6601 ttggattata atgagtcctt gaactctgat gctttgcgtt gtttttcctt ggaaagtggt
     6661 aaagagctat ggcggagatg gtatagggtt cctatgaaac gtaatcatgg cttttcgcgt
     6721 acggttccgg ttatacgtga cgagtatgtg ataacgatcg gtcctcaagg gcatgtaatg
     6781 tgttgcgatc cggtgactgg tgacttgaaa tggggtattg atatgcaaaa gcagtttaag
     6841 acggaagtcc ctttctggta taccgggcag tgtccttgcg tagatgatga tgttttggtc
     6901 ttggctccgg ccggtgaaga gactctattg gcgggtgtgg attgtcttac gggtgagatc
     6961 gtgtggagta ctccgaatac attgggttat aaaatgtcgc attcttctgt aatgccgatg
     7021 agtttgagta ataagagaac atatgtttat gccggagtgg gaggtgtttg cggcgtatcg
     7081 gcggaaaaag cggatcgggg tactctctta tgggatacaa aaaaatggca gccttccgtg
     7141 atcgctccgt ctccattacg tttgtcatca agccggatat tccttgtggc gggctatggg
     7201 acgggagggg ctctcttaca agtggataag gcaggatcga agtggaccgc tacggttttg
     7261 gaccagtata aagcggataa gggcttatct agcgagcagc agacacctat cctatataat
     7321 gatatgatca ttagcgtgat gccgaaagac ggcgggggat tacgtagtaa actggtctgt
     7381 ttctcgccta cggatttgca taatccaatt tggagttccg ctgcggatga acgttttgga
     7441 cttggtcctt atttagttat caataagcat ctgtttgttt tcaaggatga tggtgaatta
     7501 tatgtatatg agatacagtc taaagcgatg aaacttttga aaaagcaacg agtcatggac
     7561 ggtgtagacg cttgggggcc gatggcctat gcggatggga tgcttgtact gcgggatgct
     7621 catacggtta aatgtctaaa aatcgtatga tcaagtaaat aagataatca attctaaaag
     7681 ataaaaggta tggaaccgaa tcaagataat ggaaatagaa tatcgcgcaa aagttttttg
     7741 cgtatttgtg gttctgtcat agcgggtgga agtatattgg gggttaccgg taacctgtta
     7801 tggaagatgt ttacgaggcc ggatgatatt ttttatgggg tggataaaaa gagtactacc
     7861 ataaatcgta gtcatgtgaa taatattgta tccccttata ggaaggtttc cgcatttaag
     7921 atatcagacc agatcgacgc ttttgatttg tatgaaggcc ggttgattgt tgccgcgcca
     7981 aacaatattt atgtgtatga accctccggg gcattggtga gtaactttcc ggtcgggagt
     8041 tctgttcggg atgttacggt ggatgatgat cgtgtttatc ttttgtatcc tacgagggtg
     8101 gaagtctatg atctggaagg cggatggata cgggattggg aggcttgcag cgaggagtct
     8161 gattattgtt cgttgacggt tttatcaggg aatgtctttg ttacggatgc ggctaataaa
     8221 aatatttgta tgtatacgat tgaaggaggt tttgtgaagt ttattcaaag tccgtccggt
     8281 tttatcgtgc ccagctattc ttttggtatt acgaatatag atggagtggt ttactgttcg
     8341 aatccgggaa gacaccttgt ggaaagttat tcaccggaag gcgagtatat ctcctcattt
     8401 ggcaaaccgg gcggtgctgc cggcctattt agcggatgct gtaacccagt ctatttagcg
     8461 ggtacaccca caggagagat tatcacatct gaaaagggga ttcctcgaat cagttgttac
     8521 ggaaagaatg gcgagttcca tagtgtatta ttggatgaaa aagcattggg tggtggccat
     8581 gccgcttatg aggtgagagt ttgggatgac aagttggtgg tcgccggtaa agatgcgtta
     8641 tcgatatttc aatacgataa aaagctggcg gtacagaccg catgttcaac ttgtggtatt
     8701 gattgtcctt tgaagatagg tgttacgatt taaggaagaa tatggaacag aagaaagatc
     8761 atccgaaaaa tagtccgatt aaacggcgag aatttttcaa gctttgcggt tcggtggttg
     8821 ccggaggaac gatcctagcg gttgccggcg gtatggcccg gaaggtggaa ggaacggagg
     8881 ctagtttatt ctggcaaatc gatccgaatg tatgtacgca atgcggacgt tgcgagacac
     8941 attgcgtgtt acctgtctcg gccgtaaaat gtattcatgc gaataaggta tgcggttatt
     9001 gtgatttgtg cggaggctat taccgaacga acgtgaaaga gctgaatact gccgctgaga
     9061 atatgatgtg cccgacgggt gccatcctgc gtaaattcgt ggaagacccc tattttgaat
     9121 atacgatcga tgaggatctt tgcaatggct gcggcaaatg tgtgaaagga tgtagctctt
     9181 ttggaaatgg ctcgctctat ttacagatta aacaggattt gtgcctgaat tgtaatgaat
     9241 gtcaaatatc taccgtatgc gcatcgggtg ctataacgag agttccgtat gtgacggctt
     9301 ataaattaaa aggttaatcg gatgaaaaag cttttatcaa tagggaccct actctttttg
     9361 tgggtgatgc ttcaggcaca aaaccggttt ccgaaaccgg attttgagtc tggttaccaa
     9421 tatccggaat tacattatgc catacccaat gagaccttgt gggtggtatt ggatctattt
     9481 atgttggtac ttttgatgag tatcgtggta tgggcggtat ataagaaaca tacccgtaag
     9541 cctattttct gggtttcggt tatctcggta gcttattttg ggtttttccg gagtggctgt
     9601 gtctgtagca tcggctcgat acagaatata gcgttggcca tggtggattc tacttatcat
     9661 ttaccgttga cggtattgtt attttttatc ttgccaatat tatttgcttt tttgttcggg
     9721 cgggtattct gtgcgggtgt atgtccgttt ggggccctac aagaattggt gaacgtcaag
     9781 aactaccgaa tctcgaaggc agttacggct gcgttgggaa taatcccttg gttatatctt
     9841 atattcgccg ttttatacgc tgtgacgaga agccgtttta tcatctgtca gttcgacccg
     9901 tttattggta tcttccgttt aggaggagat gtgggacttc ttttgtttgg ggccttgttg
     9961 ttgattttat ctgttttcac agggagaccg ttttgtcgtt tcttatgtcc ttacggagcg
    10021 ttattaagtc ttttctcttc ggtgtctatc tggaaaattc gtctttcccg aaaagaatgt
    10081 atcaattgcg aactttgcca taattcgtgt cctgtggatg cgatccgctc tccttatgcg
    10141 aacaaggtaa aagagagccg gaaagaaggt gtacggagac ttttaggtta tttggtcgta
    10201 ttgccgttga tgatcgcggc gggggctttc ttgatgcgtt cggcaagctc ggatttgagt
    10261 cgggcaaata aggatgtgcg tttgtatgat atggtggaac ggcatgaggc gaatccggaa
    10321 gaggagctgt ctttagaatt ggaggctttt tacggacaag ggcgtacctt ggaagagctg
    10381 acgagtgcgt atgaggcgaa attggacgaa tttcgttttt attccacgat agcgggaggt
    10441 ctgatcggtt tggtaattgg tttggccttg atccgcttgt ccgtaaagcg tacccgtaag
    10501 caatatgaga tcaatcatgc ggcttgcgtg gcttgtgccc tgtgtttcag ttattgccct
    10561 cagaataaga atagtgttga actgcgtaaa tcatcagaat catgaataag gatatttaca
    10621 gaaatatagc tgcggttacg gctatcttta ttatttcgtt gtcggtcatg ttgatcacga
    10681 attattttca agtgaggggc gttacgccgc ttcagaccga ggtggtggag accttgaagc
    10741 tactgaacga tacgaatccg gataatccgg aattgcaaga acagatacgc caattggatt
    10801 tattagctcg cagggcttat tttatacaag cggatcattt gaagttgggt gtttatatct
    10861 tattgggcat ggtagccgtg ttcgttgtct gcttgcgttt ttattttaag ggggagatgc
    10921 atatcccgga taaggaaatc gatccgatcg acgaatggat gctgaagtct aaatcccgta
    10981 aatatataac atggagtatg ttcgggttgg tcggagtctc tttatttttc gtgttcttat
    11041 catctccttt cttagcaacg gagaagaccg agagtgtggc ggaggaaaca ctaatagccg
    11101 agagtacgca agttgagcct gatagtgagg tgatagaacc ggctatagat atcgaagagc
    11161 cgatgaatga agtaattata gataccacta atgatgtgac tccggtagaa gaggcttttc
    11221 ccgcaaccag tgaagagcct cagccggtag tccctaaaat tacgcataat gcgtttaggg
    11281 ggaattattc aaacggtgtg tctgcggcta aggggatacc ggtgaaatgg gatttgggta
    11341 gtggtaccaa tatcgcttgg aaaaaggaaa tacccagacc cggccataac tcgccgatca
    11401 ttaacggtaa tcatgtgttt tttacaggag cggacgagca agctcgtgag ctgtattgct
    11461 atgatctgac aaccggtgag cagcgatgga gtttggcggc tacgaatatt ccgggttcgc
    11521 cctccgtgat gccgaaggtg acggaagaca cgggcttggc ttcctcttcc gtagcgaccg
    11581 atgggaatcg ggtatgcgct atcttcgcta ccggtgatgt ggtttgtgcg gatatggatg
    11641 gtaaacagct atgggctaag aatctggggg ttccggataa tcattatggt ttcgtatcct
    11701 ctctccttat tttcggcaat acgcttttca tacaatacga taataataaa gatccgaaac
    11761 tgatcgcgtt ggatgtagct aacggtaacc agcgttgggt gaagaaccgg ccgggaaaaa
    11821 tctgttggag ctctccctct atcgcttacg tgaatcggaa gccccagttg attctaatgg
    11881 gtaacccagc gataaccgca tacgacccga attccggtga gcaattgtgg caggtggatt
    11941 gtatgggagg cgaggtatgt tcctgtccgt gtagtatcga cggggtgata ttcggagcta
    12001 acgaatacgc caagctagtg gcgattaatg gcgcggacgg aaaggttctg tgggaaagct
    12061 cggattatct gccagaggta tccagcccgg tagcgacaaa agatcatttg tatgtggcga
    12121 cgagttatgg cgtccttgcg gcttatgata caaagaccgg tgcgttggct aaagaacatg
    12181 agttgaatgt agagttttac tcttccccga tgatcgtgga aggcaagctt tatcttttca
    12241 gtaatgacgg gaagatgcat attttctcca cggataatga atttaacctg ttgagttctt
    12301 ttgagaccgg agaacgtacg atggctactc ctgcttttac ggatggaaag atcgtggtgc
    12361 gtacggaaaa gagtatttat tgtgtagcga tgaattaata tggcatgtga taattgtaaa
    12421 aataacggga tccggacaaa agaggcgatg acagcccggg tagatgcgat catcgaccgg
    12481 atcggtacgt cacgacggga tattatacca ctattgcagg ctttgcagga tgagtttagt
    12541 tacctgcctt cagatgcatt attgcgtgta tatgaacgaa cggagatcga tcgtgcccag
    12601 ttgataagcg tctctacctt ctattcccag tttcgccatg tcccttatgg gaaacatatc
    12661 attaaggttt gtaccggtac ggcttgccat gtaaagggcg cgaataatgt atatgacgct
    12721 tttcgtcggg aattgaagat ggaagaggat cgtataacga cagccgatca ggaatattcg
    12781 atagaaaaga tcgcgtgttt aggatgttgc gccttggctc cggtcgtgca gatcgacgag
    12841 aagatttacg ggcatgtaca accgggtagg gtcaatgagg tgctcgatga gttccggata
    12901 tataaccaag aacatgagcg ggaagaggaa ggaaacgcta ctcgtcagat cgtgggggag
    12961 atccgtttag ggatggagaa ctgctgtcag gcaagtggga catcagagat ttatcaggcg
    13021 gttatcaagg cctccgatga gttggggatc gaggtcaata tcaagccggt atcttgtgtt
    13081 ggagcctgca accaagtgcc tttgatcgat gtagctcatc cggacggttc tatcgaacgt
    13141 tatccgaacg taaggccgga ggagatcaaa gaaatcttat tacaccattt ccaaccggca
    13201 agccgtttga ggcgtttaaa gaattcgatc ttgaatcata tagacatgtt tcatacggat
    13261 acgacttggg ataatattct ctggaaatca gaacaggaac ggactggtgc gatcaacacg
    13321 ttcttgtctg gacaaaaacg ggtctctacg gaaggatatg gactgatgtc gccgttggat
    13381 attgatgagt atatcgcacg aggaggtttt gaggcattga aaaaggcgat tacgtcgaaa
    13441 agtcgtcaag agattatcga tacgatttta cggagtggtc ttcgtggacg gggcggcggc
    13501 ggtttcttga ccggtcgtaa atgggaactc gtggcggctt cggatcagcc tgaaaaatac
    13561 gtgatctgta atggagacga aggtgatccg ggtgcgttta tggatcgtat acttctggaa
    13621 tcttatccat taagggttat agagggtatg attatagccg gatatgccgt aggtgcgaag
    13681 gaaggaatat tctatatccg tgcggaatat ccgcaagctg ttatccgtac ccggaaagcg
    13741 atagagttgt gtcgggagag aaattgggtg ggagatcata tctttggaag tgacttttct
    13801 tttgagattt cgatatttga gggagcgggc gcttttgtct gtggagagga aaccgctttg
    13861 atcgcctcca ttgaagggga gcgaggtttt ccgcggcaac ggccgcccta tccggccgtg
    13921 gagggattga acaagcgtcc taccttgatc aataatgtag aaaccttgag ccaagtttcg
    13981 tatatagtca atcatggggt tgatgaatat cggaagatcg gtactgagaa tagcaagggt
    14041 acgaaagtat tcgccttggc gggtaaggtt cgtcatggtg gtttgataga ggtgccgatg
    14101 gggacgacct tgaaccaaat catcgaggat ataggcggtg gtgtggaagg cggcgagaaa
    14161 ttgagggccg tacagatcgg tggcccttcg ggtggttgta tccccgctca tctatgtgac
    14221 gcgaaggtgg attttgacgc acttacccaa atgggagcga ttatgggttc cgggggaatg
    14281 gtcgtattga gcgagagcaa ttgtatggtg gatgtggctc gttatttctt ggcgtttact
    14341 tgtaatgagt cttgcgggaa atgtacattc tgccgtgtcg gcattcgtag gatgttggat
    14401 atactggata aattatgtac cgggaaagcg gagatggcgg atattgataa gctggaggag
    14461 ttggccttga gcgtgaagaa agcggctctt tgcggattgg ggaagacggc gccgaatccc
    14521 gtgttggcta ccttgaaata ttttagggaa gaatatgagg aacatgtaag gggcatttgc
    14581 cgcaccggta cttgcaagga tatggtgcga ctgatgatca cggatgactg cgtgggatgt
    14641 acgaagtgct ccaaagcttg tccttcggat gcgatccctt ataccccgta tgagaaacat
    14701 tcgatagata tagagaaatg tgttttgtgt ggtttatgta tagatgaatg tagttttgac
    14761 gctatacgga aggtctcttt aaaatcttaa ggctatggtg ataacaatca ataataaaga
    14821 aatagaggta ttggagggag aaaccttgat tgaggtagct cgccgggcag gttttcgggt
    14881 cccttccatg tgctatgcga aagaagcaaa gcataaatcg tcttgtatgg tatgtgtcgt
    14941 gaggaatagt gtctccgggc aaatgatccc ttcctgctcc acgtatccgg tggaagggat
    15001 gcgtatagag acggatagcg aggaggtatc tcggcttcgt gcgttatcat tggaactttt
    15061 gttaagtgat catcgggctg attgcgaggc tccgtgtacc ttggtttgta ctcaaggctt
    15121 ggatgtggaa cgtatgttgt atttatatga tgcgggacgt tatggggaag cccgttcgtt
    15181 gttggcggct gtattcccct tgcctgcggt aggttgtgat acctgtaagg ctccttgcga
    15241 gaaagcttgc cgtaggggta cggtcgataa ggccgttgag atccgcgcca taatcaaaga
    15301 attggccggg agggtagact tacctgtcga ggatgattat catgtggcgg ataaacgtga
    15361 taagaatgtg tttatttccc gcttggggcg ttttaccatg aaggaaaaag agtggttaaa
    15421 agagactacg tccgctcctt ccggttgctt gcattgcgcc tgtggaggga aagtggattg
    15481 caagttacgc ctatacgcta cagaggctgg tatcaaacgt ccccggtatg aggtttcttc
    15541 catgttaccg gtaaaggaga agatacatgt gaaaggccgg atgtggtttg aaccggctaa
    15601 gtgtatccgt tgcggcttat gtgtttacaa tagtgagaat ggttttacct ttaagaacag
    15661 gggatttggc atgcaggtcg taattcccaa ggagagtaag acgaatgtaa aggaggaact
    15721 ggccggactt tgtcctacag gagctttgta tttagtggac taagaaaaat ctggaattat
    15781 gaaatgggtg agcttattta tgtgcatggt cggtctattg gttggctgtg agggaaatga
    15841 ggatacggtg gacgatggga atagcctgaa ctggtcgttg ttccggggag atgcctcttt
    15901 gagtggatat acggaccggt ctttaccgaa gaaaccttcc ttattgtgga gctataaaag
    15961 tggcgtacgt acggtttctt ctccaatcgt ccatcaagga actacttact ggtgtgacaa
    16021 gaaaggtcat atatggggga ttgacctaaa aggggagcct gttttcggat atgacttgga
    16081 tacgcccgta gaggctaccc cgatggttta tgattcagta ttatatatag gtaggttgga
    16141 tgggtggatg agcgctattt ccttggaatc tggagatacg ctttggaatt tcgagacgat
    16201 ggggcaaatc tccgcctcgc
//
