LOCUS       c00243_gnlPro..         4894 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKGOOGPF_243.
ACCESSION   c00243_gnlPro..
VERSION     c00243_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:47:23
            Original ID  :: gnl|Prokka|JKGOOGPF_243
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4894
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4894
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3:4539]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4..4539
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..4894
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4894
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(4..1164)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_1"
                     /sec_met_domain="OAD_beta (E-value: 3.2e-154, bitscore:
                     501.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLQFLGENIQIFLSYTGFANATPGHIVMLLVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQLGIYEEGSVLNILYQGVKQGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYIIALQMGFDPSQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERVIRMKPPRAVSQTEKIVFP
                     IVGLLLTAFLVPSGLPLLGMLFFGNLIKESGVTRRLAETARGPLIDVITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKEGNKINPLIGNSGVSAVP
                     DAARISQNVGLEYDPSNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(1169..1600)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.7; E-value:
                     3.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_2"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.4e-21, bitscore:
                     63.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNTYKVHINSVVDDVAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTNASGEPVITRQAAPSVAGAVKSPLPGVILSVDCKVGDTVKRGQKILV
                     LEAMKMENNINADRDGKIVEIKVNKGDSVLEGADLVVIG"
     CDS             complement(1624..2517)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_3"
                     /sec_met_domain="OAD_gamma (E-value: 8e-14, bitscore: 40.9,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLLMVLFSMGAKAQLTTSVKLNEVLVVNEDNFVDDY
                     GKRHPWFELFNNSAGTVDLRGCFLTNDKSNPRKYMIPKGDVLTKVPPRQHLLFWADDQP
                     TKGTFHVNFTFDPNKDNYLALYDSDGTTLIDEVTIPAGQKADVSYGLDLDGVGNWSILD
                     KVTPSTNNLTLDSNAKLENFQRNDPWGIGMTITAMAVVFLGLIILYLVFKQIGNAAIKA
                     SKRNAQKAAGTGAAVSANIGQESGEIFAAIATALYEMSDDNHDIENTVLTIHKVQRSYS
                     PWSSKLYSLRQTPNKK"
     CDS             complement(2539..4092)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_4"
                     /sec_met_domain="CT_Btheta (E-value: 5e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             complement(4129..4539)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.3e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             complement(4668..4892)
                     /locus_tag="ctg243_6"
                     /transl_table=11
                     /translation="IGLSYQLAGGTDAIMDRGFFRHLKNIWLGLDVFNILDIKNVSSYY
                     WITDVYNVQYAVPNYLTGRQLNVRLIVDF"
ORIGIN
        1 ttattaacca aggaatccta gcaagatacc ggcagctaca gcggaaccga ttacacctgc
       61 tacgttcgga cccatagcgt gcatcaacaa gtagttgctt ggatcgtatt ccaaacctac
      121 gttctgggaa atacgggcag cgtcaggtac ggcggataca ccggagttac cgatcaacgg
      181 attgatcttg ttgccttctt tcaagaacag gttaaagaac ttaacgaaca atacaccggc
      241 acaagtagcg ataacgaatg acaacgcacc caaaccgaaa atcttgatag agttcaatgt
      301 taagaactgg gtagcttgtg tagaagcacc taccgtgatg cctaacaaga tcgtaataac
      361 atcgatcagc gggccgcggg ctgtctctgc caaacggcga gtaacaccac tttccttgat
      421 caagttaccg aagaacaaca ttcctaacaa tggcaaacca gacggtacca agaaggctgt
      481 caatagcaag ccaacgatcg ggaaaacgat tttctccgtc tgtgaaacgg ctcttggagg
      541 tttcatacgt atcacacgtt ctttcttcgt tgtaagcaat ctcataaacg gtggctggat
      601 aataggaacc aatgccatat atgagtatgc ggatacagcg atagcaccca tcaagttagg
      661 agctaacttg gatgacaaga agattgcggt tggaccatca gctcctccga taataccgat
      721 agcaccggct tggctcgggt caaatcccat ttgcaatgca atgatataag caccgaaaat
      781 accaaattgg gcggcagctc cgactagcat taacttagga ttggatatca aagcggagaa
      841 gtctgtcatg gcaccgatac cgaggaatat caagggggga taccaacctt gtttcactcc
      901 ttggtataaa atgttcaata cagaaccctc ttcgtatata cctaattgta atccggcatc
      961 cttgaaaggg atatttccga tcaagatacc gaaaccaata gggatcagaa gcattggctc
     1021 gaattcatat ttaatcgcta ggaatatgaa cagcaaacct accaatagca tcacgatatg
     1081 ccctggagtc gcgttcgcaa atcctgtata ggagagaaat atttggatat tttctcctag
     1141 gaattgtaag aaactttctt gcatatcatt aaccgattac aacgagatct gcaccttcca
     1201 atacagagtc gcctttgttt actttaattt ctacaatttt accgtcacga tcggcattga
     1261 tgttgttttc catcttcatg gcttccaata ccaagatctt ttggcctctc ttaactgtat
     1321 cgccgacttt acagtctaca cttaaaatta cacctggcag cggagattta acagcgccgg
     1381 ctacacttgg agctgcttga cgggtgataa caggttcacc gctggcattg gtcggagctt
     1441 gagccggacg tttcaatgta accatttgtt ttttcgcagg tttctccatt tttacgttat
     1501 aaggggttcc gtttacctct acctctgcca catcatctac aactgagttg atatgtactt
     1561 tatatgtgtt accgttaatg gtatatttaa aacttttcat tcgtcaattg gattttagga
     1621 tgattacttt ttatttggag tctgacgcag agaataaagc ttagaactcc atggtgaata
     1681 gctgcgttga accttgtgga tagtcaatac cgtgttctcg atatcgtggt tgtcatcgct
     1741 catctcataa agagcggtag cgatagcggc aaaaatttca cctgattctt gaccgatatt
     1801 ggctgatacg gcagcacctg ttcctgcggc tttttgagcg ttacgcttgc tagctttgat
     1861 cgctgcgtta ccgatctgct tgaatactag atacaaaatg attaagccaa ggaatacgac
     1921 tgccatggct gttatggtca taccaatacc ccatgggtcg ttccgttgga agttctcaag
     1981 tttcgcattc gaatctaacg tcagattatt ggtgctagga gtcactttgt caaggatact
     2041 ccaatttcct actccatcaa gatccagacc gtaactaaca tctgcttttt gcccggcagg
     2101 gattgtcacc tcgtcgatca aagttgtacc atctgaatca tataaggcta gataattatc
     2161 tttgtttgga tcgaatgtga agtttacatg aaatgtccct tttgttggct gatcatctgc
     2221 ccaaaaaaga agatgctggc ggggaggaac tttggtaagt acatctccct tcgggatcat
     2281 atattttctg ggattacttt tatcgttcgt taagaagcat cctcgtaaat ccaccgtacc
     2341 tgctgagtta ttaaataact caaaccatgg atggcgtttt ccatagtcat caacaaagtt
     2401 atcttcattg acaactagca cttcatttaa tttaacggag gtagtcaact gtgccttggc
     2461 tcccatactg aagagaacca ttaacagtag caatacccct attttcttat ttatcatatt
     2521 catctcctgt tttacggatt atagaggcag gttatcatgt ttcttagcag gattgcttaa
     2581 cttcttagtc tgcaattgct gcaaagcacg aataatacgg aaacgagtgt tacgcggttc
     2641 gataacatcg tcgatataac cgtattgagc tgcgttataa ggattagcga atgctttctt
     2701 atattcagct tctttctctg ctgcgcatgc tttcggatct tcagcggctg ctacttcctt
     2761 ggcgaagata acctctacgg caccgctcgg gcccataacg gcgatctcgg ctgtcggcca
     2821 tgcgtaattc atatcaccac gtaaatgttt agaactcatc acgcaataag ctccaccgta
     2881 agacttacgc aatgtaacgg taatcttagg aacggtagcc tcaccataag cgtaaagcaa
     2941 tttagcgcca tgaaggatta caccgttgta ttcctgacct gtacccggaa ggaatcccgg
     3001 aacgtcaacc aatgttacca aaggaatatt gaaagcgtcg cagaaacgaa cgaagcgacc
     3061 tgctttacga gatgcgttgc tatccaagca tcctgccata accttcggct ggttagctac
     3121 gataccgacg gattgtccgt tgaaacgagc gaaacctacg atgatattct tagcgtagtc
     3181 cgcatggacc tctaggaact cgttgttatc gacgatcgta ccgataacct catacatatc
     3241 gtaagattgg ttggcgttat cgggaatgat atcgttcaat acatcatcca gacgatcgat
     3301 cgggtctttg cactcaacta acggcgtttc ctctaagttg ttctgaggta agaaactgag
     3361 caatttacgg atcaattgca aaccatcttc ttctgtatcg acagcgaaat gggctacacc
     3421 cgatttggta gtgtgtacgc tggctccacc caactgctct tgggttacat cctcacctgt
     3481 tacggttttt acgactttcg gaccagtcaa gaacatatag ctggtaccac gtgtcatgat
     3541 gttgaagtct gtcaaagccg gagaataaac ggctccaccg gcgcaagggc cgaagatacc
     3601 ggaaatctgg ggaacaacac cggaagccaa gatgttacgt tggaaaatct ctgcgtatcc
     3661 tgccaaggcg tttacacctt cttggatacg agctccaccg gagtcgttca aaccgataac
     3721 gggagcgccc atcttcatgg cttgatccat tactttacag atcttcatag ccaaagcctc
     3781 agacaaggct ccaccgaata cggtgaaatc ttgagcgaag atatatacca aacgtccgtc
     3841 gatcgtacca taacctgtta cgataccatc gcctaaatat ttagttttct cgataccgaa
     3901 gtttgtacaa cggtgttgaa caaacatgtc gaattcctcg aaactacctt cgtcaagcaa
     3961 catggcgata cgctcacgag cggtatattt gccttttttg tgctgtgatt cgattctttt
     4021 ctctcctcca cccaagcgag cttgctcacg aagtgcgatg agctctttta ctttttcaag
     4081 ctggttactc attgtatttt gatttgttgt tagaaatgaa cggattaatt atttgttgcc
     4141 cggcatgcaa agctctgtca atacgctgca agttgatttc gggtgaagga aagcgatgtt
     4201 caagccttcc gcgccaccac ggggagcttt atcgattaat ttaacgcctt tttcctcagc
     4261 ctcgttcaaa gctgcctgta catcaggtac cgcgaatgcg atatggtgga taccttcacc
     4321 ttttttctcg ataaattttg cgatcgtgct atcttcgctg gtcggctcta gtaattcaat
     4381 cttagtctgt cctaccttga aaaatgcggt ttttactttt tggtctgcta ctacttcgat
     4441 attgtagcat tttaatccaa gaacgccttc ataatagggt aaacaagcct cgatactctt
     4501 cactgcgata cctaaatgtt cgatatgtgt aagttccatg tcaataataa tttaaagatt
     4561 tagtaaatgt ttgtttctat tgtgtgcaaa tgtacactac tttttatgaa tgaggaaata
     4621 attttttgtt tttatctccc agtaaatgtg tttaaagata cattttatta aaaatcgaca
     4681 atcagacgaa cgttcaattg acgtccggtc agatagtttg gaactgcgta ttggacatta
     4741 tatacatctg ttatccaata gtaggaacta acgtttttga tgtctaatat gttaaataca
     4801 tccagaccta gccaaatgtt tttcaaatgg cggaagaagc ccctgtccat gatagcgtcc
     4861 gtgcctcctg ccaattgata ggagaggccg atat
//
