LOCUS       c00046_gnlPro..        13223 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKHBBMGF_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:30:04
            Original ID  :: gnl|Prokka|OKHBBMGF_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13223
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13223
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3223]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3223
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13223
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13223
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..493)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 84.8; E-value: 1.3e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_1"
                     /sec_met_domain="Fer2_3 (E-value: 3.5e-27, bitscore: 84.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     I"
     CDS             complement(521..2464)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.3e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(2498..3223)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="SucD_FumR (E-value: 3e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             3612..4859
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTP
                     LLAVYGMKLGGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSG
                     HTATAFMAATIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGIL
                     STELGYFLADLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLS
                     SPGATNVSVKGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRVHADPTG
                     VFTFTAGPYFSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKPPSYGTINNIVFMKGN
                     GSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKH
                     KIHYFTIGATVTALFW"
     CDS             complement(4863..6686)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLKQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFADWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHPEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRESVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDALGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVNGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             7417..7893
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MKTLVHTEKEHIEEIIRSCDVCFVGLADTDGTPYVIPMNFGYRNG
                     VIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHPEVACSYRMRSKSVIAWGKVRFE
                     EDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLVDLDEVTCKEFGAPHKKY"
     CDS             7914..8384
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIDDKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             8443..9345
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     LIFSQAEKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVXXXXXXVTK"
     CDS             9392..10969
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDKEVLYRAN
                     FCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSEDFNHSKF
                     VAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESLHKRGYRV
                     EQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGIHRKEFAF
                     EKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIEIAQKNIRSAGLAKYVELKTM
                     PFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWILSYKDECF
                     DKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSASRPRPSFP
                     EKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERGDGRPARK
                     QFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRPFKKPFRR
                     EDNDDFED"
     CDS             10953..13169
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MTLKIKHFLVLCVFALSTSMTLMAQDKQLTLHDLLPGGKTHNKFV
                     PASLKQLQWCGDTYLYVKGDSMICGVPEKKEQVAFTRSRLNEALSAAGLPTVGSLPGFS
                     VPYKDQPVLAFTSKGHRLHYNFAENKIIGNYQLDSKGSNYNFCPANNCLAFTVGNNIQI
                     LSPENQTSIVTRETKDGIVCGQAVHQREFGISKGLFWSPAGSALAFYRMDESMVTDYPI
                     VNIDARQAKAEPVKYPMAGMKSHEVTVGVYNLSTGETVWLETGTPKEKFLTNIAWSPDE
                     KSIYIAELNREQNEMNLVRYSALTGKKEAVLFTETNEHYVEPQYSVLFLPNDPGKFIWQ
                     SQKDGYNHLYLYDTTGKQLKQLTQGEWVVTQVIGFDAKGENLFITSTQPHIRSSFNYGT
                     PMNVNGWKLNLKKGETSLLTPNAALESVHNLSVSASGKYAIDSYDAPKIPRIINLIRTK
                     DGKEIKNLLTARDPYKGYTLPEIEAGTIKSADGTTDLHFRLVKPVGLDENKKYPTIVYV
                     YGGPHSQLVTGGWQNGVRGWDIYMAQRGYVVFTVDNRGTSNRGFAFESVIHRNLGVNEM
                     ADQMKGVEYLKSLPYVDADRIGVHGWSYGGFMTTNLILTHPDVFKVGVAGGPVIDWSNY
                     EIMYGERYMDRPQDNPEGYKNANLKLKAGNLKGHLLQIHGDIDPVVVWQHSLGFLKACV
                     DADTYPDYFVYPRHEHNVTGKDRPHLYEKITRYFDDYLKNTNKE"
ORIGIN
        1 cgatacatgc agcagcatcc atagccattt cagcatctgc acgaggaata gcgattgaat
       61 tggcatcagg tacaccacct gtgttcactg atacgaaacc acctgcctgg ataattttat
      121 cgtaagcata acggtctacc atcaagtcgc ggattaccgg gaaaccggca gaacgccacg
      181 gttcgattgt aatagtttcg ccatcattga agcgacgcat ataaagctgg caagtagttg
      241 cgccggttgc aggtccgtgc ggatgtccgt ttacatacaa agaacacata ccgcagatac
      301 cttcacgaca gtcgtgatcg aatacgatcg gctctttacc ttcactgacc aaacgttcat
      361 tcaaaatgtc taacatttcc aggaaagaaa cactctgatt gattttgtct atttggtaag
      421 tctcaaattg tcctttatct ttcggacttt tctgacgcca aactttaagt gttactttta
      481 tatctttatc catgattcta atttttgtga ttgatgatta ttacttcttg tagttacgtg
      541 tttgaggaac aacgaactga tagttcaaat cttccttcag cataaccgga tctttgtctt
      601 caccctggta ttcccaacaa gatacgtaca tgaacttatc gtcatgacgc agggcttcgc
      661 cttcctcggt ctggtgctct gtacggaagt gtcctccaca agattcggca cggtccaatg
      721 catcgtgtgc catcaatgta ccaatctcaa taaagtcagc caaacgcaat gccttatcca
      781 actctacgtt caggttatcg gcttcacccg gaatatatac attactccag aactctttct
      841 tcagctcttt caacatctgg atcgcttcct gcaaaccttt tgcatcacgt gccataccta
      901 catgttccca catgatatga cccagtttct tatggataga atctaccgac tctttaccct
      961 tgatactcat caatttcttg atgcggtctt tgatcccctt ttcagcttct gcaaactcag
     1021 gcaggtcggt actgaaacgc ggaacctgga tctggtctga cagatagttc tggattgtat
     1081 aaggcaatac aaagtagcca tcggccaatc cctgcatcaa cgcagaagca cccagacggt
     1141 tagctccgtg gtcagagaag ttagcttcac cgatagcgaa cagacccgga atagaagtca
     1201 tcaattcata gtcaacccac agaccaccca tcgagtagtg caatgcagga taaatcatca
     1261 tcggagtttc gtatggatcg tcgttggtaa tttcttcgta catgtcgaac aagttaccat
     1321 atttagcttt tacaacatct ttacccagac ggttgatggc gtcggagaag tcgaggaaca
     1381 cggccagacc tgtgttgttc acaccgaagc cggcgtcgca acgttcttta gcggcacgtg
     1441 aagcaacgtc acgcggaacc aggttaccga atgccggata acggcgttcc agatagtagt
     1501 cgcggtctgc ttcaggaatg tctttccctt tcttagttcc ggcctgtaat gcttttgcat
     1561 cttccagttt cttcggaacc cagatacgac cgtcgttacg caatgattca gacatcaaag
     1621 tcagcttaga ctggtagtca cctttcaccg gtacacaagt cgggtggatc tgcaccatac
     1681 aagggttagc gaagtaagca cctttcttgt agcactgcca tgcagcagaa ccgttggaag
     1741 ccattgcgtt agtagacagg aagaaagtat ttacataacc acctgttgcc accactactg
     1801 cgtgagcaga gaaacgttcg atctgacctg tgatcaggtt acgtgcgatg ataccgcggg
     1861 cacggccatc caccttcaca acgtccagca tttcgtggcg ggtatacatc tttactttgt
     1921 tcaaaccgat catacggctc aaagcagagt aagcacccag caacaactgc tgtccggtct
     1981 gaccgcgggc atagaacgta cgggatacct gagcaccacc gaatgaacgg ttatccagca
     2041 gaccaccgta ttcgcgagcg aaaggaacac cctgtgctac gcactggtcg ataatagagt
     2101 tggaaacttc agccagccga taaacgtttg cttcgcgggc acgatagtca ccacctttga
     2161 ttgtatcgta gaacagacgg taaacagagt caccatcatt ctgataattc tttgcagcat
     2221 tgataccacc ctgtgcggcg attgagtgtg cgcgacgggg agaatcctgg atacagaagt
     2281 tcaatacgtt gaatcccatt tctgccagag aggcagcagc agaagcaccg gccagaccag
     2341 taccaactac aatcacgtcc agacgacgtt tgttcgcggg gttcaccagt ttctgatgat
     2401 ctttataatt tttccacttc tcagccaacg ggccctgagg gattttagaa tctatttgag
     2461 tcataatgat ttattttcaa tattgttaca ccttaaatta atgtcctgca caaacagcta
     2521 catagtcacc acctacacca ttcaggtaga aaacgatagt aatgatagca aacactacgc
     2581 aaataacggt tgctacaatc ttggaaatgc agatccaacg gttcatccag atcgtgttac
     2641 tccaaccgat agtctgaata gcgctccaga acccgtgagt caggtggaac cacaaagcta
     2701 cgtaccatac cagatacagc actgtattca ggatattacc ctggaaatag tagttgataa
     2761 acgctgcacc gtcctgagga gatacggttg ttgttccgtc gcaaagtgtt accatgtgat
     2821 tgcctaggag ttcggcgaac atcatcttat accagaactg gctgaagtgc aacaccatga
     2881 acaggataat gataataccc agtaccagca tgttctgaga tgcccattcc acacctttcg
     2941 gacgagcgtt aattgcataa cggtcgttac cgcgagcctt acggttttgc agtgtaagga
     3001 gaacagcata cacaaagtga atcacaacgc ctgctgccag caccaatgtt gctgccacgg
     3061 cataccaatt tgctcccaac aatgaacaaa tcatgttata ggcttctccc gagaaagcag
     3121 ccgccacatt cattgacaag tggaacaata agaacaaaac aagaaaaagg cctgatacac
     3181 tcattatcag cttcttcccg atagaagaat taagtaacca cataagataa taatttaagt
     3241 tatttaattg tttttagaaa ttcatatcaa tatactcaat tatcaggcaa aggtatgcta
     3301 aatacacgta tcacgcaaac gattaaagaa atatttcgtc aatcaaacct atacatttca
     3361 ggagggacaa acggtaaatc ctattcaata aataaattaa caaaaatgta accagtacta
     3421 accggcattt ttatatcttc gtggcataat caggggatcg tatgttacaa cgtaaaatgc
     3481 tgagcttctt atttatgatg atttttatac cgtctgttcg tgctcagtga aaagatagta
     3541 cgagattcat aaataaagaa catgaatttg aaaccactta caacaaaata tcagagaata
     3601 aggtatacca gatgctacgt gtccctgttc ctcttttcgc catttcagcc ataacatatg
     3661 ggcagggtga taaattccgg acattgcgca atacgcatac gcccaacttc cattacagat
     3721 acgatgattt tctgcaatat actccgttgc ttgctgttta cgggatgaag ctcggcggtg
     3781 tggaaagtcg tagttcatgg ccccggatga tcgtatcgaa cgctttttcg gcaacgatca
     3841 tggccgctac cgtcaacagc atgaaatata cgatcaaacg cgaacgcccc gacggctcaa
     3901 agaacaactc attcccttcg ggacacacgg caaccgcttt catggctgct accatcatgc
     3961 accgggaata tggtctgacc cgcagcccgt tatatagtat cgggggatat acagtcgcca
     4021 cagccaccgc tttcagccgg caactgaaca accgccactg gctgagcgac gtactggccg
     4081 gggccggtat cggcatctta tccacagagt tagggtattt tctggcagac ctgatcttca
     4141 aggacaaagg cttgaatctc cctgacaagc tcagggagtc tgcccccaaa ggagggcgcc
     4201 cttctttcct ggagttcgcc gtaggataca gtatcatcaa cggaagtatc gaggtaggta
     4261 aaaatatacg cctgagctcg ccgggagcaa ccaatgtcag cgtaaaaggc ggttacttct
     4321 tcaatcctta tttcggtatc ggcggcgaaa taacagcgct ggcaagcccg atggcattcg
     4381 acatgtcgct ttatacagga acaacccctt caaccaaata tgacatcacc cgcgtccatg
     4441 ccgatccgac cggtgttttt acttttacgg cagggcctta tttttcgtta ccagtagcaa
     4501 gcaagctgct tttaggaaca aagttccagg ccggatattc ctacctggtg aaaaatgaag
     4561 tggaaatgga cttacaggaa aagcccccct catacggaac cataaataat attgttttta
     4621 tgaaaggcaa cggtagcagc aactatgttt tacgcacagg catttcagcg accgggatcg
     4681 tcagccgcaa cctgggtatc cgtatgttcg tagattacga ttatacgttc ctgaaagcac
     4741 cttacgaaat cttaaccagc ctcagagaca gccaaccagt ctacggcgag agccatttaa
     4801 gcaagcacaa aatacactac tttacgattg gcgcaaccgt aacggcactg ttctggtaat
     4861 tatcagtcag cagcaggaac cagccggact ttgatatcgc tctcctgccc gctttccaga
     4921 ctcacatcga aaacgatacg gcaggttccc tcattggaag catcatagct attcttcgat
     4981 acattatcaa ggacggacac agaagttacg gacggactat caacgatcag ttgcatacat
     5041 ttgccgtctt ttgtcagttc caccatatga ctgtccaata cacggggaat ggccccggtt
     5101 acaatcgtcc atctgacagt tgccggctga ctgccagctt ttacacgatc aatcaccgac
     5161 agatattttt cattgatcag agcaacttca cggacggcat tttccaattc tccgccgaac
     5221 aagtccgtca tattcagaga agctccgagt ttatgcgctt ccgaatagat atttgtcaca
     5281 ggtacaaaac cgtttacatc atggtattta ccgtttacag tcagtgtatt atgcgccagg
     5341 ttattataac ggaacacatt ccagcgctgc ccgttctgcg acatattcca taaatctaca
     5401 ttttcctttt ccagcgaata atattcctgc atccccaggt cctgcaccca gcgaacaccc
     5461 aaagcatcga acacaaacga tccggcatcc atatgggcat ggctggtcga agccgttcct
     5521 ccttttattc ccagatagaa accttctcca ttctcccaac ccgtacggac cagcacgaca
     5581 ggcgtctgtc cgttagccgc ccacaatttc atggcaggag gtaccagttc attcatttta
     5641 tattgtgaac cataaatcgg aatcaacgga aggaaacggc tctcctcatc cgaaaaagac
     5701 aactccgccc gactcaacat atccttttca ttccaaagca gtgtagggtc ttgcagcttg
     5761 tcggcaaacc agtacatagc cggcaaagca aagacactct cacgggaatc gctgaagtta
     5821 aagcatttac cggtcgttcc ggtcataaac tgcataaaac gggcagaagc cagaaaacct
     5881 tcagccgaag agagaccgcc gtcagtcccc agggcggatt ccaacgcggc attcaaaaga
     5941 acctggaagg tagtcccgta tccccaataa ttatatcctt cgggataagc gccatcggga
     6001 ccatagcctt tcaaagtcag gccgactgta gataaagcac gttcaatgat ttcacgggcc
     6061 tcttccggat gatcttctaa aacggcaagt gcaccgtaaa ccagtccggc attacagacc
     6121 tggttccagt tattggtcgc tctcagaaac cagttatatc ttttatccct cgacggggca
     6181 aaacctttat tcagaatcgc ctcctgcacc agcctccggg catccggaga taaccgatcg
     6241 aacaaccagt cataaccgat tgcaaccgcc atagtcattt cgcccgtatc cagaaaatgg
     6301 gacgggttcc aatcggcaaa cgaacacacg gcaatcattt cctgctctgc ccgcaaacga
     6361 tacttatcct ctcctgtcat ccggtaagca tatgaaagat agaagatacg ccgcaaggct
     6421 tcacgcgata cggccagcaa ccgtttccct tcttttttat atgccagcac aggcgtcgtg
     6481 atcagatcgt cgcattgctt gagaagatag ttatgcaacc ggagcatttc cggattaaga
     6541 gccagatcgg atttaatctt ttgctcctct cctttcttta ccagcaaccg gggatgagaa
     6601 gggtaagaat caaagcgtat tccctgtgaa taccccgaaa cgaacaggga aaagcaaaac
     6661 acaacaagca ggatagtttt attcatacag gtattatatt taattggagt tacaaatata
     6721 ggaaatcgct tgataaagtg ttttcttatc cggaatcctt ttaacagaca ataaaatacc
     6781 attttgctac aatttacaac gattaaagat cattttgtat attttttccg catatacgta
     6841 tctgctatat ttcacaaaac agtagaaata gaagatccga aaacacaata tttaacactt
     6901 agcgtattca tatagatttt cactcttcat tttaaacaaa ttgtaatctc gtttaaaacg
     6961 aatttttttt cattttaaat gaaatggaga tttattgcag atgaaaaatt tgttaattct
     7021 gtccaaaaaa gttattttaa acaggccttg ggacctcaaa tcacatgcta aacaacacat
     7081 tttatctcca gaacgagtaa atatccaaac caaacccgaa cagcacattc atatatttca
     7141 aatgtacttt acgacattta tcaacaacta ccacacatca tcaaacataa agccacattt
     7201 attaatcaac aattaaaata aagacattcg caatcatccc gtagagcgaa taaaaacaac
     7261 aaacctgatt taggacacgt acagctcact gacagaaggg ctatttgaca ttttgacaca
     7321 ttgacgaaaa cagtacatat ataataaagt cgcaaaagta agtccgagaa gttgaacttt
     7381 tttactatgt ttgcaaaagc ataattaaaa atagtaatga agacactggt acacacagag
     7441 aaagaacata tcgaggagat tatccgtagt tgcgatgtct gtttcgtcgg actggctgat
     7501 acggatggta cgccttacgt tattcccatg aactttggct atcggaacgg tgttatctat
     7561 ttacattcag cgcaggaagg ccgaagtatc tcaatcctgg aacgtaaccc gaaggtttgc
     7621 atcaccttca gcaccgacca tgatctggta ttccagcatc ccgaagtggc ttgcagctac
     7681 cgtatgcgtt ccaaaagcgt tatcgcatgg ggtaaagtgc ggtttgaaga agacttcgac
     7741 aagaaaacgg aagcgctgga tataattatg aaacagtatt cggacaagga attccgttat
     7801 tccgacccgg ctgtgaaaaa cgtaaaaata tggctggtag acctcgatga agtaacatgc
     7861 aaagagttcg gggcaccgca caagaaatac taaacattta agagagtgaa tatatgaaaa
     7921 atctgttagc aatattttta atggtgttcc tgttcgcttc atgcgaagga ccgatgggcc
     7981 ctccgggacg agacggggaa gatggcggta taacctactg gatatttgac aaggatatac
     8041 aagttaagtc aagcgactgg gaattagtcg acaatggtaa taacgaacct ttttacatgt
     8101 atgagtacag aattgacgat aaagatttcg acatatatca ggatgcttat aaagaaggct
     8161 taattacctg ttacatgtat ctggatcacg gcgaagacaa agaagcacaa actgcattac
     8221 ccaaccctgt caatcgaata gataaagaga ataatatctg gacggaaacc tatgcagccg
     8281 aatacaccaa agacggtttc atcatcttca aagtgacatt ctccgacttc tttactgatc
     8341 aacggccgcc ggaaacgcat ttcaaagcag ttataaccta ttaaaagtac acatatatca
     8401 gatatttaat gtacttttgc ccaaaataag actttcaaaa taatgggatt gcaaaagcat
     8461 agcaaggtat tgaatgaaac agtagaaaag ctttcggacg aatgttcata caaacaactg
     8521 tttcatgcct accgcgatga agaggcattg ccttcaggtg aagtactgga ggagatcatt
     8581 gacttgtgcc gtgcaatcct gtttcctggc tattacggga atgcgcggat cagtacacag
     8641 acgatccgtt tccataccgg ggtcaatatt gaaaagttgc acgagctgct cagccgtcaa
     8701 atctatgcgg gcctttgcct ggccgacacc agctgtactt cctgtgcgga agagctgatc
     8761 ttcagccagg cagaaaaact ttccgaagcg ttcatttcca cactgccgga aatgcgctgt
     8821 ctgcttgcca ccgatgccga agccgcctac aacggtgatc cggcagcaca aaacatcaat
     8881 gaagttatct tctgttaccc gggcttccgg gcaataggca attatcgtat agcgcaccag
     8941 ctttataagt tgggcgttcc ttttataccc cggatgatca ccgaaatggc tcattccgaa
     9001 accggtatcg acattcatcc gggagctcag ataggacatt atttctctat cgaccacggc
     9061 acgggtaccg tgatcggcga aaccagtgtg atcgggaata acgtacgcat cttccagggt
     9121 gtcagccttg ccggagaaaa gctgccgccc gatgagaacg ggaacgcgat ccgcggtgtc
     9181 ccccgccatc ccatcctgga agacaatgtg accgtctact ccaacgcgac gctattgggg
     9241 aaaatacggg tcggcaaagg tgccacgata tgcggcaacg tctggatcac cggagatgtt
     9301 ccccccggtg ctgtcannnn nnnnnnnnnn nnagtaacta aataaatatc ttttcttaca
     9361 acgcacgcaa atgaataacg agacatttga aatggtggcc aaaaccctgt acgggttaga
     9421 agaaatactg gccggtgagt tattagctat aggcgccaac gatatagaaa ttggccgccg
     9481 gatggtatcc ttcacaggag ataaagaagt gctttacaga gccaacttct gttgccgcac
     9541 cgccttacgc atcctgaaac cgatctatca tttcaaggca aaagatgccg atacggttta
     9601 taaggaagtg aaaaaggtcg tatgggaaaa ctatatgtca ctggacaaga cgttcgcgat
     9661 cgactccgtg atctattcag aagatttcaa tcactctaaa ttcgtggctt accgtacaaa
     9721 agatgcgatc gttgactact ttatggagaa gcacaacaaa cgtccttccg tacgtgtaaa
     9781 caatcccgac ttatacatca atatacatat ctcgcacaac gattgtacct tgtctatcga
     9841 cagttcgggc gagagccttc acaaacgcgg ataccgtgtg gaacagaccg aagcgccgct
     9901 gaacgaagtg ctggctgccg gtatgatcct gaagacaggc tggaaaggcg aatccaattt
     9961 cgtcgacccg atgtgcggtt ccggtacgct gctgatcgaa gcggctatga tcgccctgaa
    10021 catcgccccg ggtatccacc gcaaggagtt cgctttcgag aaatggatcg acttcgacca
    10081 ggaactgttc gaccgcatct ataacgacga aagccaggaa cgcgaattca ctttcaaatg
    10141 ctacggttcg gatatcaacc cggccgctat cgagatcgcc cagaagaata tccgtagcgc
    10201 aggcctggcc aaatacgtcg aactgaaaac gatgcctttc cagcaatata cggaagcacc
    10261 gcaaccgggt atcctggtaa ccaacccgcc ttatggcgaa cgtatctcct cccgcgacct
    10321 gctgggactt tataatatga tcggcgaacg cgtcaaacat gtgtttaccg gatataaagt
    10381 atggatactc agctacaaag acgaatgttt cgacaagatc ggcctgcgtc ccagcgaacg
    10441 gatgaagctg atcaacggct cgctcgactg cgaataccgt tgttacgaaa tatttgaagg
    10501 aaagaacaaa gactataaga aagcattgaa cgaggaaggc gcggaaagaa cggaagattc
    10561 cgcctcacgc ccaaggccct cgttccctga aaaaagatat gacacccgtc ctgcaggtcg
    10621 cccgaacttc aagaccgacc gcatggaccg ccccgaccgt cgtttcgccg ctgctcacag
    10681 tgaagacgaa aacgaacgta catccgcagc accgggaaaa cgtttcttcg gtgaagaacg
    10741 cggtgacggc cgtcctgccc gcaaacagtt cggaggcgaa cgtggtgaac gcccggttcg
    10801 tccgattttg cacaaagccg gtgaaaaacg ccccgtcaaa atgcgttaca aagacgaaga
    10861 cgacaggttc tctaaaaaca gaaagaactt cggagacaga aaacgcggag aaggccgtcc
    10921 attcaagaaa ccattcagaa gagaagacaa cgatgacttt gaagattaaa cacttcctgg
    10981 ttctttgcgt gttcgcttta tctacatcca tgacgctgat ggcacaggac aaacaactca
    11041 cattacacga cctgcttccg ggagggaaga cacacaataa gttcgtcccg gccagtctca
    11101 aacagctaca atggtgtggg gacacttacc tgtatgtcaa aggagacagt atgatatgcg
    11161 gcgtacccga aaagaaagag caggttgcct ttacacgcag ccgactcaat gaggcgcttt
    11221 cggcagccgg acttccgacg gtaggcagcc tgcccggatt ttcggttccc tataaggacc
    11281 agccggtact ggcttttacc agtaaaggcc accgcctgca ttacaatttt gccgaaaaca
    11341 agataattgg caattatcag ctggacagca aaggatcgaa ctataacttc tgtccggcca
    11401 ataactgcct ggcattcacg gtggggaaca acatacagat tctttcaccg gagaatcaga
    11461 cgagtattgt tacacgtgaa acaaaagatg gaatcgtctg cggacaggca gtccatcaac
    11521 gtgaattcgg catcagcaaa ggactgttct ggtcaccggc aggttccgcc ctggctttct
    11581 accggatgga cgagagcatg gtcacagact atcctatcgt caatatcgac gcccgccagg
    11641 caaaagccga accggttaaa tatccgatgg ccggcatgaa gagccatgag gtaacagtcg
    11701 gtgtgtacaa cctctcgaca ggcgaaaccg tctggctgga aaccggaacc ccgaaagaaa
    11761 agttccttac caacatcgcc tggagcccgg atgaaaagag tatctatatt gccgaactga
    11821 accgcgaaca gaatgagatg aacctggttc gctattctgc cctgaccggc aagaaagaag
    11881 ccgtcctttt cacagaaacg aacgaacatt acgttgaacc gcaatattcg gtactcttcc
    11941 tcccgaacga tcccggcaaa ttcatctggc aaagccagaa agacggatac aaccacctgt
    12001 atctgtatga caccaccggc aaacaactaa agcaactgac acagggagaa tgggtagtca
    12061 cccaggtaat cggtttcgat gccaaaggcg agaacctgtt tatcacttcc acccaaccgc
    12121 acatacggag ttcgttcaat tacggcactc cgatgaatgt aaacggctgg aagctgaatc
    12181 tgaagaaggg ggagacatcc ctgctgacac cgaatgccgc cctggaaagt gtacataacc
    12241 tttcggtcag cgcctccggc aaatatgcga tcgacagtta cgacgctccg aaaatcccgc
    12301 gcatcatcaa cctgatccgg accaaagacg gcaaggagat caaaaacctc ctgaccgccc
    12361 gggacccata caaaggctac acactgccgg aaatagaagc tggtaccata aaatctgccg
    12421 acggtacaac cgacctgcat ttccgcctgg tcaaacctgt cggactggat gagaacaaga
    12481 aatacccgac catcgtctac gtctacggtg gcccccactc acaactggta acgggcggct
    12541 ggcagaacgg cgtaagaggc tgggatatct atatggcaca acgcggctat gtggttttca
    12601 cggtcgacaa ccgcggcaca tctaaccggg gattcgcttt cgaaagcgtg atccaccgca
    12661 acctgggtgt caacgagatg gccgaccaga tgaaaggcgt ggaatacctg aaatcgcttc
    12721 cttacgtgga tgccgaccgt atcggtgtgc acggatggag ctacggcggc ttcatgacga
    12781 ccaacctgat cctgacgcat cccgatgttt tcaaagtcgg tgttgccggc ggtccggtga
    12841 tcgactggag caactacgag atcatgtatg gagagcgtta tatggaccgt ccgcaagata
    12901 atccggaagg gtataagaac gccaacctga agctgaaggc aggcaacctg aaaggccatc
    12961 tcctccagat acacggcgac atcgacccgg tagtagtatg gcaacatagc ctgggcttcc
    13021 tgaaagcctg cgtggatgca gatacctatc ccgattattt cgtctacccc cgccacgagc
    13081 acaacgtgac aggcaaagac cgcccgcatc tctacgagaa gataacacgg tatttcgatg
    13141 actacttgaa gaatacgaac aaagagtaac acacccctta tcccctctca agaggggaaa
    13201 cagttaccat cagataatat aat
//
