LOCUS       c00117_gnlPro..        10837 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKHBBMGF_117.
ACCESSION   c00117_gnlPro..
VERSION     c00117_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:30:04
            Original ID  :: gnl|Prokka|OKHBBMGF_117
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10837
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10837
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6786:10835]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6787..10835
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10837
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10837
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(618..722)
                     /locus_tag="ctg117_1"
                     /transl_table=11
                     /translation="MNIMSVNGLWRKQTYFLFVHSRKGKHTFINITDI"
     CDS             complement(1402..2175)
                     /locus_tag="ctg117_2"
                     /transl_table=11
                     /translation="MISGNYAEVVWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGP
                     IYSFLDYFVDEQFVKLFEEKEDRYQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQS
                     ATRPEVCLMRGAEMLLIMAEAAAQKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDI
                     YVERRKELICEGQAGFYDLVRLQKRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIG
                     TLESNDYRFFCQIPQMEILNNDAISESDQNPWSGQ"
     CDS             complement(2120..2641)
                     /locus_tag="ctg117_3"
                     /transl_table=11
                     /translation="MCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLI
                     QNYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDM
                     WLINSKICSXXXGPCLPGDAELGRRLQRSQDRLRPAQPVDDPRTIPFRFRRYDLRQLCG
                     SGMGHEIYSR"
     CDS             complement(2667..2984)
                     /locus_tag="ctg117_4"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKNT
                     G"
     CDS             complement(3003..4892)
                     /locus_tag="ctg117_5"
                     /transl_table=11
                     /translation="MYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVN
                     TEFTLPFNLKFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKR
                     STTWNNVLSGEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGV
                     SGGRDKYSLLSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKE
                     GFMEDLKWIDNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLK
                     PSTYPTPDLKWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSAS
                     GYNMNIGDLRNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACT
                     YKMEEGKSLYEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAI
                     PKVFGAITNNFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQP
                     GDTDVLIPRWSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVY
                     VTGNNLLTFGPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(5110..6288)
                     /locus_tag="ctg117_6"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGMITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQXXXXWWKNSLFLLRRLSGRPGIW"
     CDS             complement(6787..7833)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_7"
                     /sec_met_domain="IlvN (E-value: 1.2e-48, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(7875..8606)
                     /locus_tag="ctg117_8"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(8643..9197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_9"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-18, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(9210..10835)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_10"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.1e-51, bitscore:
                     162.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GYPGGQAIPIYDSLYDYRDQLKHILVRHEQGATHAAQGYARVSGK
                     VGVTVVTSGPGATNTITGIADALMDSTPMVVIAGQVPSPLLGTDAFQEVDVIGITQPIT
                     KWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLDLAKDAQVGLVDYEYQKVDYVRSYQP
                     EPDIREERIEAAASLINNAKKPFCLVGQGVILGGAEEELKEFLLKNDIPAGSTVLGLSA
                     LPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLDI
                     DNSEIGKNVPVDVKVLGNAKHTIPMITALLEERKRPEWNAEFEPDEKEEYNKVIEKELY
                     PTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGF
                     GLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELGTIMQENLNVKIIVLNNNFLGMVRQW
                     QELFFNERYSNTIMKNPDFVAIAKAFGIASRAVDKREDLDEAIAEMLNHDGAYMLVANV
                     ETCGMVYPMVPAGGSVTNMILGDK"
ORIGIN
        1 ttgtgctttt gcgatcccgt gtcgagcacg ggaacgggat agttcaaata tttctatatt
       61 gaaacatcct tttgctgcgg ttgccttgtt tactattgat gatttacttt ttgggatata
      121 aaagccaagt cctatccgga gaacatacta ttggatacaa agcgtcagga gagttcctgg
      181 aagttaaagg attgtcaaaa tgatatttta tgtatgtgct gaaggaannn nnnnnnnnna
      241 ttgtacgggc aaagggaaat gtcgatctgt ttttatagaa atctcgccga cttacctttg
      301 ttcgctttga cctgattgtt gcaatattca tatcacaaaa aatgtatatt atctatgatt
      361 gttacccata taccacatct attcataatt tattaacata ttgctatttt acacacacat
      421 caaaaagcgg ttgctctgga aataaaaact gtctaaaaac atatgatttt ctttttttta
      481 aaagcactaa ttgaggtgtt tttcttctct aaacgaataa aaactccact acaatagaaa
      541 tttatctcag tttaaacgaa attgaaaccc gtttaaacta aaattttctt gggtttaaac
      601 gagataaaaa atcgatatca gatatctgtt atgttaataa atgtatgctt cccttttcta
      661 gaatgaacaa ataaaaaata agtctgtttc ctccaaaggc catttacact cataatattc
      721 atatatcatt catttttata tcattttgat tttgccgtct gtttggttac aggaagtgaa
      781 gtttccatac gactctgatt tgcatcgacc gtttcactga tatcatgttc actattatcg
      841 gttgaaagag aaactatttt tcgcaatgac atacgtttac tggtaattct ggatcaggnn
      901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntt gatgtgtttt ttctgtggta
      961 caaatattat caggcaactc tttccgatat ttattatgag agataaaccg gatttatttt
     1021 ctaccaaccc tttcgacata cgaaaaaaga agtaatctgg agccggaagt aatcgaaaag
     1081 attgccaaag cattagatat acccgaagaa gcaattacgg aactaggcga agccacttcc
     1141 attaatatct tttccggcac ctggcaagat aatgctaatt gccagaatta taatcctaca
     1201 tttaccccct tagaaaaagt cgttgaatta tacgaacgtt tattgaaagc ggagcaggag
     1261 aaggtggcca tgttacagga agtgctaaag gacaaaaagt aaaacagtga acatnnnnnn
     1321 nnnnnnaatg ttacaaataa aagagaggga ggcatgtaat aaacacctcc ctctctttta
     1381 tttatttaca acagatgaaa cttactgccc gctccacgga ttctgatctg attcggagat
     1441 cgcatcatta ttcaggattt ccatttgcgg gatttggcag aagaaacggt aatcgttcga
     1501 ctccagcgtc cctatcggtt gcggatcgag cgcattatat ccgttcagat actgcatgcc
     1561 ccatacgtaa tgtccggcag gattggtagt tgattcaccg atacgaacca atctcttttg
     1621 caggcgcacc aggtcataaa aaccggcttg tccttcacag atcaactctt tacggcgttc
     1681 cacatagatg tcttccagca aagcttcgcc tccggcattg gttgtcgggg tagcattacg
     1741 tgccacctgc aaacggttca gcagattcag ggcctcaccg gaattaccct tttgggctgc
     1801 agcttcggcc atgatcagca gcatttctgc tccgcgcatc aggcagactt ctggacgggt
     1861 agcgctttga ataacgcttc cgccgtcttc accataatgc ttgtatttgt cgaaagccca
     1921 ttttgtattg atttccgtat tcgcattgtt cgtacgtttc cagaactggt aacggtcttc
     1981 tttttcttca aacagtttca caaactgctc atccacgaag tagtcaagga acgaatagat
     2041 agggccgtcg gcataaccct caccgtagct ggcatcctgg ttataccaga aattgaactg
     2101 cgtactaccg cccaggttat tatcggctgt atatttcatg gcccatacca cttccgcata
     2161 attgccggag atcatatcgt cgaaaccgga acggtattgt tcgcgggtca tcaactggct
     2221 gtgctggtcg tagacgatct tggcttcgtt gtaagcgccg tcccagttct gcatcaccag
     2281 gtaaacacgg gccnnnnnnn nnngaacata ttttggagtt gatcagccac atatcgtccg
     2341 gattataatc ggcaagcaat gttttagccg tcgtcaggtc ggacacaatc tgggtataga
     2401 cttcctctac ggtagaaaaa cctttatggg attcatcatc ggaagaggta cgcaggatca
     2461 ccccacgctt gcttttagct atcgcatacg tctgttggta attctggatc agatggaaat
     2521 actggattcc acgcatcgcc agcgcctgac ctttgatatg tttcttctgt gtctcatcac
     2581 cggcagcggc atccacattg gtcaggatga tattggcacg gttgatcaca ttatagcaca
     2641 tcgaccagat ttttgaggca tttccgtcag cctgtgtttt tgagttggnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2761 nnnnnnnnnn nnnnnnnnnn nnnnncacgg tcgcctttat cggtattaaa atacagctgc
     2821 ttataggctg aagtcaatac tttttccaac tgggagacat tccccagtac atcttcatcg
     2881 tttactttca cataggagct ggttgtcagg tcgtcgttac atccggtcag ggccatacca
     2941 gcaaaaacca gggacaggaa ggatatattt ataaatcgtt tcataaatat cattttttac
     3001 gtttacaatg tgatttgaat accgaccata tacagtcttc tcgaaccctg aataccgtta
     3061 tcggtttcag cattaccgtt ataactgtta cccattatac ctgtttcggg gtctgtgtag
     3121 cgttttttgg caggaccgaa agtcaacagg ttattaccgg ttacataaac acgcaggttt
     3181 tctaccaggg ccttgcgggt aaggctctta ggcagcgtat agcctaatgt caggtttctc
     3241 agacgccagt agtggttgtc gaacacgaag ttatctgcat attttaccgt cgcgccatac
     3301 tggttgtacg accaacgtgg gataagcaca tccgtatcgc ccggctgacg ccatctgtcc
     3361 tcaaccaact cctgtatcac accgacaccc ggacggttca tgatacgttc tttatatgta
     3421 tagtccgata ttttggaacc ataagaataa tagaacatga acgacaggtc gatccctttg
     3481 aactggaagt tattggtgat agcaccgaac actttgggaa tcgcggagcc acagtacaca
     3541 aaatcgtctg tcgttacttc ttcctgcttt tccgtacgtt tccaaccgcc gttaccatcg
     3601 cggatcaacc agccgggtac tccggtttcc ggattaacac catcgtactg gggagcgata
     3661 aattcataca gggacttgcc ttcttccatc ttgtaggtac aggcggtacc agaataagtg
     3721 taaggacctg taggcaaata agtcacctca tttttcagcg tactcatgtt ggcatcgata
     3781 tcccatctga aatctttcgt tgtaaggata ttcgcattca atgtgatttc aatcccgcta
     3841 ttacgcaggt caccgatatt catattatac ccagatgcac taccaacctg ggcagacaga
     3901 ggcagttcct tataatacaa caaatcatgg gaagtacggg aataatattc cactgtaccg
     3961 ctaagtcggt tgaatacgga gaaatccaaa ccgatattcc attgctgatt actttcccac
     4021 ttcaagtccg gtgtcggata ggtagatggt tttaaaccgg atttcagata caggtcatca
     4081 ctttcataag taccctggta tccgtaaagg acttcatccc ctgccttacc attcgattca
     4141 cgcacaatca gcttatcatt accagtcgta ccgtaactac cacgcaacga aaggttatca
     4201 atccatttca ggtcttccat aaaaccttct ttcgatattc gccacgaacc gcctgtcgac
     4261 cagaatgtac cccagcgatg atcggaactg aaacgggaag aaccatcctc acgaagcgaa
     4321 gcggacaagt aatacttatt caagaagtta taatcgactt taccgaagaa cgaaagcaga
     4381 gagtatttat cacgtccgcc ggaaacaccg aagttcttgg tggtattcga taattcatat
     4441 ttacccagtt ccatgatacc ttcaccccaa ccttgttcgt agtgggagtc ccaggtatac
     4501 cactcatgtc cgaccagacc tgaaatcgta tggtcaccaa tcatccattc accagacaat
     4561 acattattcc aggtggtgga acgtttattg aaattataac ggctggcata accaccgtct
     4621 gccagtatag aaataccata aggtgcagtc tgtccgctgc catgtacggc ggaagtatat
     4681 tgcatggtac gataccagta atcgtcaata ttcaaagccg aacggaattt caggttgaaa
     4741 ggaagagtaa actctgtatt tacctgggca gacaggatat gccccatatt gttatcgaaa
     4801 ctgtcatcgt tcggattatc ccaataatca cccgagttat tcaggatatg ggcaccaaag
     4861 aagttattgg tatatttacc gtaactgtac atccgttccc ctgttttttc agaaacgacc
     4921 caaccggtat tatcttcatt acgtaaccag ggtgaagaca aagtcgtcgt aaagttagcc
     4981 gcacggctgg caccaccgga aaggttctgg cgatgacgcg aataagaaag gctaccggcc
     5041 actttccacc aatcgaacaa ctctgtactc aggttggtac ggaaagaata acgtttataa
     5101 tactgccggt taccatatcc ctggtcgtcc agataaccgc cggagaagaa ataggctgtt
     5161 tttccaccat tnnnnnnnnn nctgaccact tatatccaca ctataatcct ggcgcagttt
     5221 acgggagaag atagctttgt agacatccca atcatcttca tcccagacat attccagatt
     5281 aggattcatg taaggattcc cattgccgtc atgcaatacg taattttcat tgatatgtct
     5341 gaacggagtg acataaatca gattaccatt cgaatctttt gtagccttta cctgtttggt
     5401 caatgcctgt gacgaagcat aatcgcccgc ctgttgcata ttcatgccgt cataaagaag
     5461 ggcatcataa tacaaggcat accaggtatt ttccagctgc tggtacggat cggctttttt
     5521 cggattcttg acagcattat ccgaagtacc ccaacctccg cggaagttaa tacgcggttt
     5581 ttctgattta ccccgcttgg ttgtaatcat tacgacgccg tttgctgcac gcgaaccgta
     5641 aagcgaagtg gccgccgcat ccttcagcac cgtcatcgat tctatgtccg taggattgat
     5701 ctggttcagt tttccatcgt aaggcatccc gtccacaata tataacggat cggcctttcc
     5761 ggacatggaa gcaataccac ggatctccac acgggcatca gctccggggt taccctgtac
     5821 attcacaaca ttcacaccgg cactcatccc ctgcaatgct tccgcaaagc cggagcccat
     5881 gatcttttcg agtttttcag cttttacaac ggaggccgat ccggtgaagg ttgatttctt
     5941 agccgttcca taggctacga caacgacttc atccaggtcc tgtgtcgcat cacttaattt
     6001 tacatttaaa atagattgtc cgttccaagt gatctcctga gtggccaggc cgacaaagga
     6061 aataacaata accgctcccc gccgaacatt atccagcgta aactttccat cgatatcggt
     6121 tatcataccg atagtggttc ctttcactac aacagaagct ccggcgacag gtcccatttg
     6181 gtcctctacc aggccggtta ccttattacc ctgttgtact accatcgttt ccggacctgt
     6241 aggattggca gcaatcgcac ctgccgcacc taataataca gaaatcatta gtgatctaat
     6301 tagttttgag ttggtccaca tagctaaatt caagtcttta attaaataaa attaatcaca
     6361 atagcgttca tttcattaga ggttacactt ttctaagata aaagtgactg gcatacattt
     6421 caataaaata aagttaacta aaacaaagat atactgatca ttacacacaa catcctatat
     6481 ttccactcta caaactacag tatctccatc agcaaatata acttatcatt atttaataca
     6541 agcataatta tgtatattta ttgctctaat aaatatattt taaccaccat ttaattgatt
     6601 tttttatcta aaatccacat tcaaacaatg acatacatat tgggatgaaa aatcaataac
     6661 agttgcaatc aaaaacattt tttaaccatt aacacattac ataaaccata aaaaaacggc
     6721 aacccgaaaa gccggattgc cgtttttata tcacaaaatg tttaactatt aatgtatcac
     6781 catttattag ttgttttcag gacgaagttt acgaacaaca gcacctgcac gccacatttc
     6841 actttcgcga agagcagcca gttctttttc cagaccttca cgatagtcag gcttgctgtt
     6901 tgtgtcgata gaacgctgtg cttcgttacc gcaggcaact tcgctataca acttctggaa
     6961 caccggtttt gtagcatcgt ggaacgggcc catccagtcc aaagcaccac gctgtgcagt
     7021 tgttgaacag tttgcataca tccagtccat accgttttct gcgaacaacg gcatcaatga
     7081 ctgagtcagt tcttctactg tttcattgaa tgcttcagaa ggttcgtgac cgttttcacg
     7141 caaagtttcg tactgagcca acagtaatcc ctggatagct cccatcaaag taccacgttc
     7201 gccggtcagg tcagaataaa cttctttctt gaatgttgtt tcaaacaagt aaccagaacc
     7261 aacaccgata cccagtgcaa tcacgcgatc ccatgctttg cctgttgcat cctggaagat
     7321 tgcgtagctt gagttcagac cacgaccctg caagaacata cggcgcagtg aagtacctga
     7381 acctttcgga gcaaccagga ttacgtctac atcagcagga gggatgatgt ttgtacgttc
     7441 tttgtaagtg atgccgaatc cgtgagagaa atacaaagcc ttacccggag tcaggtattt
     7501 tttgatgcgc ggccaaactt caatctgagc agcatctgaa agcagatact ggatgatagt
     7561 cgctttttcg catgcttctt cgatatcgaa cagtgtttcg cccggtaccc aaccgtcagc
     7621 aacggccttt tcccaggtct taccaccttt acgttgtcct acaattacgt taaaaccgtt
     7681 gtcgcgcagg ttcaggctct ggccaggacc ttgtacgccg taacctatta cagcgattgt
     7741 ttcgtctttc aatacttctc ttgccttttc caacggaaat tcttcgcggg ttactacgtt
     7801 ttcgtcaacg ccgccaaaat tcattactgc cattttcttt ttactattaa aatgtatata
     7861 aaataatttg tttttcagat ccaggtaacg gcagcgcggc tgatggcttt gccgtcgtta
     7921 cagattgcca tattatattt accgggggat acttcctggt tatggagagt cagctccatc
     7981 ccatactttc cttcggactg ataagctatt tcgaaacggc ttatctcttt ttctcggaac
     8041 agactgatat cgaacaagtc gagcaggtgt tccatgtatt tgatactgtt caggtggccg
     8101 tttacgtcca ggtcactgta cttcacacgg taaggttcgc cggaagtgtt gttttccacc
     8161 ggagcaattt tacccggttt ttcaatcgga cagggacggt cggtgatata agcactcagg
     8221 ccctccacat cgagcaaggt cgggcggcgg gtttccatat cgatagccgc ccagatagag
     8281 cgggcaaagc caaaggtctt gccttcgccg ttcaccagtt caaagcaacg gctggtaaac
     8341 aacttaccga cctcatccac ccaggtatat aaagttacgg attcagacat ggcaggataa
     8401 gaagtcatct cgatagccag acgggaaaga acccaggcgg tatgcctttc ggtcatatcg
     8461 ttatatccga atccacggtc ggcggcatgg caagaagcag catgcaacaa ataagttccg
     8521 atcataggga ttgtaatacg tccccggaag tccatcagat aagactctgt tacgaaatga
     8581 aattctccta ctttgttctt ctccataatt tactttattt acaaaatgtt tccttattat
     8641 tctcagacat gtttttcctg caacttcttt tccattgcag ataacatgtc gctcagacgt
     8701 tctaccttac tcttcgttat agcaacgcgt ccggaacgga taaattgcag gacaccgatc
     8761 gtctcactca attctttaaa caaagcctgt gtctcatcat aatgaccact cttttccaac
     8821 accacacaat cctcattcat ttcaaggata cgggcattgt acttacggat cagatcctca
     8881 accgtcccca tcttgataaa gagttcggta ctcagtttat aaagagcgat ttcctggtaa
     8941 accaggtctt catccgtatt ataataagct ttcaggatat ccacacgctt gtcgatctgt
     9001 tttacgacct tgtcgatcgt atcctcgtcg gcaaaggtag taattgtaaa cttatgtatt
     9061 ccctttatag cagagggaga aacagaaagc gtctcaatgt tcagttgccg gcgcgtaaag
     9121 ataacagtta tctgattcag aagaccaaca gtgttttccg aaaagataat aacggtatat
     9181 aattgttttg tattcatagt ttctcctcct tacttatcac ccaaaatcat gtttgtcacg
     9241 cttcctccgg ccggaaccat cggatatacc ataccacaag tttccacatt ggcaaccaac
     9301 atataggcac catcgtgatt caacatttca gcaatcgcct catccaagtc ttcccgttta
     9361 tctaccgcac gggaagcaat accaaaagcc ttggctatcg ctacaaaatc cggattcttc
     9421 atgatggtat tcgaataccg ttcgttgaag aacagctcct gccactggcg taccattccc
     9481 aggaaattgt tgttaagaac gatgatcttt acattcagat tttcctgcat gatagttccc
     9541 aactcctgga tagtcatctg gataccaccg tcgccggtaa agaaacagac cgtacggtca
     9601 ggcgctccca gcttcgctcc aatggcggcg ggaaggccaa agcccatcgt tcccaaacct
     9661 cctgaagtaa ctacgctgcg tgtttgttta tatttgaaat agcgaacacc catcatctgg
     9721 ttctgaccta catccgtaac cagaatcgca tcattatcgg ttgcttcgga aaccttacgg
     9781 actacttcgc ccattttcag ttggccttcg gtaggataga gttctttttc tattacctta
     9841 ttatattcct ctttttcatc cggttcgaat tcagcattcc attccggacg cttccgttct
     9901 tccagtaaag ccgtaatcat cggaatcgta tgcttggcat ttcccagcac tttcacgtcg
     9961 accggcacat tctttccgat ctccgaattg tcgatatcca ggtggataat ctttgcctgc
    10021 ttggcataag tcttcaagtc gccggttacg cgatcatcga aacgcatacc gatagcaatc
    10081 agcacgtcac attcgttagt cttgcggttc ggtccgacat ttccatgcat ccccaacata
    10141 cctttattta atgggaagtc cgaaggtaat gcagacaagc ccaatacggt agaaccggct
    10201 ggtatatcgt ttttcaacaa gaattctttc agttcttctt cagctcctcc taggataacc
    10261 ccctgcccta ccagacagaa tggctttttg gcattattta tcaatgaagc agccgcctcg
    10321 atacgttcct ccctgatatc cggttcaggc tggtaactac gaacataatc cactttctga
    10381 tactcataat ctaccaaacc cacctgtgca tctttcgcca aatccagtac cacaggtccc
    10441 gggcgaccgg tcgatgcgat atagaaagca cgggaaacgg cccaagcaat ttcttccggg
    10501 cggcgtatct ggtaagccca tttggtaatc ggttgtgtga taccaattac atcaacttcc
    10561 tggaaagcat ctgttccaag cagcggagac ggaacctggc cggcaatcac caccatcggt
    10621 gtactgtcca tcagcgcatc ggcaatacca gtgatggtat tggttgcccc gggacccgaa
    10681 gtaaccaccg ttactcccac ttttccggaa acacgggcat atccctgtgc agcatgtgtt
    10741 gcaccttgtt cgtggcgcac cagaatatgt tttaactgat ctctgtaatc gtataaacta
    10801 tcgtaaattg gtatcgcctg cccacccgga taaccga
//
