LOCUS       c00050_gnlPro..        11385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IMPIMKPL_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:15:37
            Original ID  :: gnl|Prokka|IMPIMKPL_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11385
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11385
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:10062]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..10062
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..11385
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..1270)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_1"
                     /sec_met_domain="Proton_antipo_M (E-value: 6.5e-70,
                     bitscore: 225.2, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLLLKEELSLILVIVILFVADLFMSPDAHKNDGKPVLNTM
                     LPIVLLTIHTLITIVPGPVADAFGGMYHNQPIQSIVKSILSIGTLIVFLMAHEWMRRPD
                     TAIKQGEFYILTLSTLLGMYFMISAGHFLMFFIGLETASIPMAALVAFDKYRHHSAEAG
                     AKYILTALFSSGLLLYGLSLIYGTVGTLYFADIPARLTGDPLQIMAFVFFFSGMGFKIS
                     LVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLMAILIKVFAPMVEQWQEVLYWVII
                     ASITIANLFALRQQNLKRLMAFSSISQAGYIMLGVISGSAQGMTSLVYYVLIYMFANLA
                     VFTVITIVALRASKFTLEDYNGLYTTNPKLAFLMTLALFSLAGIPPFAGFFSKFFIFAA
                     AFEGGFHLLVFIALINTIISLYYY"
     CDS             complement(1392..2876)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_2"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.9e-67,
                     bitscore: 216.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSLFVLIPLLMLLGLWLSRNIAQIRAVMVTGASALLVLSAAL
                     TVMYLNARHAGATDEMLFRADMVWYPALNIHYSVGVDGISVAMLLLSAIIVFTGTFASW
                     RLQPLTKEYFLWFTFLSIGVFGFFISIDLFTMFMFYEVALIPMYLLIGVWGSGRKEYSA
                     MKLTLMLMGGSAFLLIGILGIYYGAGATSMNLLEIAQMHNIPIEQQRIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAAQELGWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMMNQTACTGAVLQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELSGLMKIMPFLAVCYVIAGLANLGLPGLSGFIAEMTI
                     FTGSFQHPDTFHRVWTVIACSSIVITAVYILRLVGKILYGTCTNKHHLTLSDATWDERT
                     AVIILIACVAALGMAPWWISGMIGDSVLPITDLFTI"
     CDS             complement(2928..4841)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_3"
                     /sec_met_domain="Proton_antipo_N (E-value: 1.3e-25,
                     bitscore: 79.0, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 1e-86, bitscore:
                     280.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYTILILLLPFLSFLALGLGGKWMSHHTAGLIGTAALGVVAVLS
                     YLTAGMYFSAPRLADGTYEALMPYNFKWLPFTESLSIDMGILLDPISVMMLVVISTVSL
                     LVHIYSFGYMKGERGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILVYGYYAGTYTFSPNEMALAKGGAAMIPLA
                     LGLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIEYA
                     PSVLHIVAYVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSANPHEGG
                     LGYMAGMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHITFLIACLA
                     IAGIPPFSGFFSKDEILTACFQFSPIMGWIMTVIAGMTAFYMFRLYYGIFWAGSEPGQK
                     SASDGGDSHMPHPHESPLAMTLPLMLLAVVTIVAGFIPFGHFISSNGEAYNIHLDWSVA
                     GTSIAVAVVSIAIATYIYAGSRQPVADTLAHRFKGLWTAAYHRFYLDEVYQFITHRIIF
                     GCICHPIAWWDRHVVDGFFNFLAWGAEATSEEIRGLQSGRIQQYTFVFLLGTLALILLL
                     LL"
     CDS             complement(4900..5208)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_4"
                     /sec_met_domain="Oxidored_q2 (E-value: 9.3e-23, bitscore:
                     69.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLIVSAIMFFAGIYGFFTRRNTLAILISIELILNATDIN
                     FAVFNRFLFPGGLEGYFFSLFSIAISAAETAVAIAIMINIYRNIRSIQVNKLDEMKW"
     CDS             complement(5214..5726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_5"
                     /sec_met_domain="Oxidored_q3 (E-value: 2.7e-35, bitscore:
                     110.9, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITLETVVFYFLAAFITVFSILTVTTHRMVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDVIEKLKRSRFLAGLGATVGG
                     AIIVVFITLKHKFIATTDVEPLEVNIKTIGHHMLSGDKYGYLLPFEAVSILLLACIVGG
                     LLIARKR"
     CDS             complement(5757..6260)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 30.2; E-value:
                     8.7e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_6"
                     /sec_met_domain="Fer4_7 (E-value: 2.9e-13, bitscore: 40.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.1e-06, bitscore: 16.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKNSYIGGLIHGVTSLLTGMKTTMTVFCRRKTTEQYPENRSTL
                     KLSDRFRGTLTMPHNDKNEHRCVACGLCQMACPNDTIKVTGEMVETEDGKKKKILVKYE
                     YDLGSCMFCQLCVNACPHDAITFDQDFEHAVFDRTKLVMTLNRPGSHVEEKKKPAASKE
                     ETTK"
     CDS             complement(6318..7403)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_7"
                     /sec_met_domain="NADHdh (E-value: 8.9e-121, bitscore:
                     392.4, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVFDFSIVTNWIHQMLTSLMPEGLAIFLECVVIGVCIILMYAV
                     LAIILIYMERKICAFFQCRLGPMRVGKWGLLQVPCDVIKMLTKEIIDLKFSDRFLYNLA
                     PFMVIIASFLTFACLPINKGLEVLDFNVGVFFLLAASSIGVVGILLAGWSSNNKFSLIG
                     AMRSGAQIISYELSCGLSILTMVVLMGTMQFSEIVEGQADGWFIFKGHIPALIAFIIYL
                     IAGNAETNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGG
                     WMPLHIVGLDGFNAVMDYIPGFVWFFGKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYL
                     VPISMVNLILMVLIVVFKLHF"
     CDS             complement(7535..9124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_8"
                     /sec_met_domain="Complex1_30kDa (E-value: 4.5e-36,
                     bitscore: 113.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 2.3e-82,
                     bitscore: 265.8, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKYIEPSVLHDEMLRLRKEKQMDFLECLSGMDWGIPDEKDAPD
                     TPRGLGVVYLLESTVTGERIAVRTATLNREHPELPSVSDIWKAADFNEREVYDFYGIVF
                     IGHPDMRRLYLRNDWVGYPMRKDNEPEKDNPLRMDNEETVDTTMELELNPDGSIKNKEM
                     QLFGDEEYVVNIGPQHPATHGVMRFRVSLEGEIIDKIDANCGYIHRGIEKMCESLTYPQ
                     TLALTDRLDYLGAHQNRHALCMCIEKAMGVEVSERVQYIRTIMDELQRIDSHLLFYSCL
                     AMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADIAPGFVKKVKEFIP
                     YLRGILHEYHDVFTGNIIAQQRLKGVGILSREDAIAFGATGGTGRASGWACDVRKRMPY
                     AVYDKVDFKEIIRTEGDSWARYLIRMDEILESLKIIEQLIDNIPEGAYQEKMKPIIRVP
                     EGTYYAAVEGSRGEFGVFLESHGDKMPYRLHFRSTGLPLVSTVNTICRGAKIADLIAIG
                     GTLDYVVPDIDR"
     CDS             complement(9140..9721)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_9"
                     /sec_met_domain="Oxidored_q6 (E-value: 2.9e-26, bitscore:
                     81.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTKKPKIKSIPYEEFTDNETLEKLVRELNAGGANVALGVLDDF
                     VNWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMADPKYVVAVGGCAVSGGPFKKSYHVVNGLDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKYFGGVNRKEENH"
     CDS             complement(9712..10062)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_10"
                     /sec_met_domain="Oxidored_q4 (E-value: 5.9e-39, bitscore:
                     122.0, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTLLVVVLLTAIAFVGIVIALSNAIAPRSYNAQKMEPYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFEVETVFLFPWAVITRELGVAGLFSVLFFLIILILGL
                     AYAWRKGALEWK"
     CDS             complement(10174..10497)
                     /locus_tag="ctg50_11"
                     /transl_table=11
                     /translation="LHDSATGAADILCVPATRQAECCTLSQAPTTQQAVQKFYDLFSPN
                     SLCIEHVDHTQVPTNKSVLLRMYIYKMQQHAYAPECDRLLNLSPHPVPDANYYVFGLRK
                     III"
     CDS             complement(10649..11383)
                     /locus_tag="ctg50_12"
                     /transl_table=11
                     /translation="VISIFMFISGNNFTLLLLFVNRKFKKFISNAELKFYFGSVVLFTA
                     VIAIVLYYTSPMGMEESFRKSLFQVISLQTSTGFATDDYMQWTPVLWGLLTIIMLMGAC
                     AGSTTGGLKCIRMVILTKVSRNEFKHILHPNAILPVRINKQVISPSIVSTVLAFCFIYI
                     SIIVIGTLLMMAMGVGAEESMGCVISSIGNMGPGLGETGPAYSWNALPDAAKWLLSFLM
                     LLGRLELFTVLLLFTPDFWKRN"
ORIGIN
        1 gatagtaata aagcgagatg attgtattga taagggcaat gaataccagc agatggaagc
       61 cgccttcgaa agctgccgcg aagatgaaga acttcgagaa gaagcccgca aacggcggga
      121 tgcctgccag agagaacagt gccagtgtca tcaggaacgc caacttcgga ttagtagtgt
      181 acagcccgtt atagtcttca agtgtgaact tgcttgcccg cagtgccaca atcgtgataa
      241 cggtaaatac ggcaagattg gcaaacatat atatcagcac gtagtatacc agcgacgtca
      301 taccctgtgc gcttccgctg atgacaccca gcatgatgta acctgcttgc gagatactgg
      361 agaaagccat caaccgcttc aggttctgct ggcgcagggc gaagaggttg gcaattgtga
      421 tggaggcgat gataacccag tacagcactt cctgccattg ctccaccatc ggagcgaata
      481 ccttgatgag aatagccatc agcacgaaag cggcagagcc tttagagatg acactcagat
      541 aggctgtcac cgtgcttgga gcaccttcgt aaacgtctgc tgtccaaaga tggaaaggca
      601 ccagtgatat tttgaatccc atgccggaga agaagaatac gaatgccata atctgcaacg
      661 ggtcgccggt gaggcgtgcc ggtatgtcgg caaagtagag agttcctacc gtaccgtaaa
      721 tcaaggataa tccgtacaac agcaatccgc tggagaacag tgccgtgaga atatatttgg
      781 cacccgcctc ggcagagtga tggcggtatt tgtcgaaggc aaccagcgct gccatcggga
      841 tacttgccgt ctccaggccg ataaagaaca tcaggaagtg tccggcggaa atcatgaagt
      901 acatacccag cagggtggaa agtgtcagaa tgtagaactc accttgtttg atggcagtgt
      961 ccggacggcg catccattcg tgggccatca ggaatacaat cagtgtacct atactgagga
     1021 tggatttcac gatgctctgt atcggctggt tgtgatacat gccgccaaag gcatcggcca
     1081 caggaccggg gacgatggtg ataagtgtat gtatggtcag cagaacaatt ggcagcattg
     1141 tgttcagcac cggtttgccg tcattcttgt gtgcatccgg actcatgaag aggtcggcga
     1201 caaaaaggat gacgatgacc aatatcagcg aaagctcttc tttgagcagg aggaattggg
     1261 aataatccat atctatttac gattttacga tttacgattt acgattgaaa ttactcttgg
     1321 gatttacgat tttatgattt acgattgagg ttactcttgg gatttacaag tcatttatca
     1381 atcgtaaatc gtcaaatcgt aaataaatca gttattggca gcacgctgtc tccaatcatg
     1441 ccgctaatcc accatggtgc cataccgagg gcggcaacgc atgcgatgag gatgatgacc
     1501 gctgtacgtt cgtcccaggt tgcatcgctc aaggtgaggt gatgcttgtt agtgcaggtg
     1561 ccatagagaa tctttcctac cagtcgcagg atatagactg ccgtaatcac gatggagctg
     1621 catgcaatga ccgtccacac gcggtggaac gtatcgggat gctggaacga accggtgaag
     1681 atggtcattt cggcaatgaa accgctgagt ccgggtaatc ccagattggc aagaccggcg
     1741 attacatagc agacagccag aaaaggcata atcttcatca gaccggagag ttcgcggacg
     1801 tcacgcgtat gggtacgtcc gtatatcata ccgataaggg cgaagaacaa ggctgtcatc
     1861 agtccgtgag agagcatctg cagaacagca cccgtgcaag ctgtctggtt catcatcagg
     1921 atggcgaaca acaccaggcc gcaatggctg acggaagagt aggcattgat atacttcaag
     1981 tcggtttgta cacaagcgga gaatgcaccg tataccacgg agattccggt aagaatcagg
     2041 aatatccatc ccagttcttg tgcagcttcg ggcatcaggt acatggctat gcggaaacat
     2101 ccgtaacctc ccagtttcat caatacaccg gcatggagca tggatacggc agtcggtgcg
     2161 gaggcgtgac cgtcggggct ccatgtgtgg aacgggaaca gagcgcccag cacaccgaaa
     2221 ccgaggaagg tgagcgggaa ccagatacgt tgctgttcga tgggaatatt gtgcatctgt
     2281 gctatttcca ataggttcat agaggtggct ccggcaccgt agtagatacc caggataccg
     2341 ataagcagga aggcggagcc gcccatcagc atcagtgtca gcttcatggc ggagtactcc
     2401 ttgcgtcccg acccccatac accgataagc agatacatgg gaatgagggc aacctcgtag
     2461 aacatgaaca tggtgaacag gtctatcgag atgaagaacc cgaacacacc gatggagagg
     2521 aaggtgaacc aaaggaaata ttctttagtc agcggttgca gcctccagga ggcgaatgtt
     2581 ccggtaaaga caatgatggc cgaaagcagc agcatggcta ccgaaatacc gtctactcct
     2641 accgaatagt ggatgttgag tgcaggatac cagaccatgt cggcacggaa cagcatttca
     2701 tccgtggcac cagcgtggcg tgcattgagg tacatcacgg tcaatgctgc agaaagaacc
     2761 agcagagccg atgcaccggt caccatcacc gcgcgtattt gtgcgatgtt gcggctgagc
     2821 caaagaccca gcaacatcag caaggggatg agtacgaata atgataaaaa gttcatcttt
     2881 atatttacga tttaacgatt tacgatttac gattgaaaaa tctcgggtta tagcaatagt
     2941 agcagtatca gtgccagcgt gcccagcagg aatacaaatg tatattgctg gatgcgtccg
     3001 ctttgcaggc cgcgtatctc ttcactggta gcttcagccc cccaggcaag gaagttgaag
     3061 aaaccgtcga ccacgtggcg gtcccaccat gcaatggggt ggcagatgca gccgaagatg
     3121 atgcggtggg tgatgaactg gtagacctcg tccagataga agcggtggta agctgctgtc
     3181 cacaagcctt tgaaacggtg tgccaatgta tcggcaacgg gttgccggct acctgcatag
     3241 atgtaggtgg caatggctat ggaaaccacc gctacggcga tacttgtacc tgccacactc
     3301 caatccagat ggatgttata tgcttcaccg ttggaactga tgaagtgtcc gaaaggaatg
     3361 aaaccggcaa ctatcgtaac cacagcaagg agcatcaggg gcagggtcat cgccagagga
     3421 ctctcgtggg ggtgaggcat gtggctgtcg cccccatcgc ttgccgactt ttgtcccggc
     3481 tcagagccgg cccaaaagat accataataa agacggaaca tatagaatgc tgtcatacct
     3541 gcaatcactg tcataatcca tcccatgatg gggctgaact ggaagcatgc cgtcaggatt
     3601 tcatctttgg agaagaatcc ggagaacgga ggaatacctg caatggcaag gcaagcgatg
     3661 aggaacgtga tatgcgtaat gggcatatac ttccgcagtc cacccatggc agacatctcg
     3721 ttgctgtgta cggcatggat gatgctaccc gctccgagga acagcaatgc cttgaacatg
     3781 gcgtgtgtga acaagtggaa catgcctgcc atgtagccca gtcccccttc gtgtgggttg
     3841 gctgatgtac atacacccag cgccaccatc atgaaaccga tttgggagat ggtggagaat
     3901 gccagtacac gcttgatgtc actctgcaca catgccacac tggcggcata gaatgccgtg
     3961 aaggctccta cgtatgccac gatgtgcagc acgctgggag catattctat gaacaacggg
     4021 aacatgcgtg ccaccagata gacacctgca accaccatcg tggcggcatg aatcagtgca
     4081 ctgaccggcg taggaccttc catggcatcg ggcagccaga tgtgcaacgg gaacatggca
     4141 ctctttccgg caccaccgat gaacatcagt cccaaggcaa gcggaatcat tgccgcaccg
     4201 ccctttgcca gcgccatctc attagggctg aaggtgtatg taccggcata atacccatag
     4261 acgaggatac ctataaggaa tcccaggtca gcaaaacggg tcacgataaa agccttcttc
     4321 gaagcggcaa tagccgccgg cttcgtataa tagaaaccaa tcagcagata ggaggacacg
     4381 cccaccaact cccagaacag atacatctgg aagatattcg ttgctactac cagtccgagc
     4441 atggacatgg tgaagagcga caggaaggcg tagtaacgct ggaaaccgcg ttcgcccttc
     4501 atgtagccga aagagtatat gtgtaccagc agcgaaacgg tactgatgac cacgagcatc
     4561 ataaccgaaa tcgggtcgag taggataccc atgtcgatac tgaggctttc tgtgaaaggc
     4621 agccatttga agttataggg catcagcgcc tcgtacgtac catcggcaag gcggggagcg
     4681 ctgaagtaca ttcctgcggt gagataggaa agcactgcga ccacacccag tgccgcagtt
     4741 ccgataaggc cggcagtgtg gtgtgacatc catttacctc caagtcccag agcgaggaaa
     4801 gagaggaaag ggagtagaag gattaatatt gtatattcca tatatactat gtttatcaat
     4861 tattactatt caagaaacat cgcttggcga ttcttgctct taccacttca tctcatccag
     4921 tttgttcacc tggatgctgc ggatgttgcg gtagatgtta atcatgatgg caatggctac
     4981 agccgtttcg gccgccgaga tggcgatgga gaataaagag aagaaatatc cttccagtcc
     5041 tccggggaat aggaaacggt tgaatacagc aaagttgatg tccgtggcat tcagtatcag
     5101 ctcgatgctg ataagtatcg ccagcgtgtt gcggcgggtg aagaacccgt agatgcctgc
     5161 gaagaacatg atagccgaaa ctatcagata atattccatg tgtatcataa ttcttatctt
     5221 ttacgtgcta ttaataatcc acctacgata catgccaata acaagatgct gacagcttcg
     5281 aagggaagca gataaccata cttgtcaccg ctcagcatgt ggtgaccgat ggtcttgatg
     5341 ttgacttcca aaggctccac gtcggtggtg gcaatgaact tatgcttcaa agtgatgaat
     5401 actacgatga tggcaccgcc cacggtggca cccagtccgg caaggaacct gctacgcttt
     5461 aacttctcga tgacatcgcc ttcgccactg gtaagcagta tggagaagac gtagagcact
     5521 acgataccgc cggcatagac cataatctgc acggaaccga ggaaggtgta acccagcaga
     5581 aagtagatgc ctgccgtacc gaaaagcacg aacagcaggt aggtggccga gcgcaccatg
     5641 cggtgggtcg ttaccgtcaa gatggaaaat acggtgataa aggccgcaag gaagtagaat
     5701 actactgttt caagagttat ttccatgttg tttaattaca agttactatt aacgaattac
     5761 tttgttgtct cttctttgga agcagcgggt ttcttttttt cttctacatg gctgcccgga
     5821 cggttcagcg tcatgaccag tttcgtgcgg tcaaacactg catgctcaaa atcctggtcg
     5881 aacgtgatgg catcgtgagg gcaggcattc acacagagtt ggcagaacat gcacgaaccg
     5941 aggtcgtatt cgtacttaac caatatcttc tttttcttgc cgtcttccgt ttcaaccatc
     6001 tcgccggtca ccttgatagt gtcgttggga caagccatct ggcacaaacc gcaagctaca
     6061 caccgatgtt catttttatc attatggggc atggtcagcg tgccacggaa acggtcggag
     6121 agtttcaatg tcgagcggtt ttccggatat tgttcggtag tctttcgtcg gcagaatacg
     6181 gtcatggttg tcttcatacc tgtcagcaga gaagtgacgc cgtgtatgag tccgccgata
     6241 taagagttct tttctttcat tacttttgcc tttattaaaa ttatccgcaa ggaaatcttg
     6301 ctccggcgct acgccggtta gaaatgcaat ttaaatacta caattaatac catcaaaatc
     6361 aagttcacca tagagatggg taccaggtac ttccactcca gattcagaat ctggtcaata
     6421 cgcaggcggg ggaaggtcca ctttatccac atcagcagga agactacgaa gaaggccttt
     6481 ccgaagaacc atacaaatcc cggaatgtaa tccatcactg cgttgaagcc gtccaggcct
     6541 acgatgtgta gcggcatcca gcctcccagg aagatggtgg ctgccacgga ggctacgata
     6601 aacagattca aatattctgc cagatagaag aatccgaagc ccataccgct gtattccgta
     6661 tggtatccgg cagtcaactc gctttcggct tcgggcaagt cgaagggacc gcggttggtt
     6721 tccgcatttc cggcaatgag gtagatgatg aaggctatca atgcagggat atgtcccttg
     6781 aagatgaacc agccgtcagc ttgtccttct actatttcgg agaactgcat ggttcccatc
     6841 aacactacca ttgtcagtat gctcaatccg caggacaact cgtagctgat aatctgcgca
     6901 ccgcttcgca tggctccaat cagcgagaat ttattgttgg aactccagcc tgccagcagg
     6961 atacccacta cgccgatact cgatgcagcc agcaggaaga acactcctac attgaagtcc
     7021 aatacctcca atcccttgtt gatgggcagg caggcaaatg tcaggaaaga agcgatgatt
     7081 accatgaacg gtgccagatt gtagaggaac cggtcagaga atttcaaatc aatgatttcc
     7141 tttgtcaaca tcttgatgac gtcgcagggc acttggagca atccccattt ccccacgcgc
     7201 atcggaccga ggcggcattg gaagaaggcg catattttac gctccatgta aatcaggatg
     7261 atggcaagca cggcatacat caagatgatg catacgccaa tcaccacgca ttcgaggaat
     7321 attgccagac cttccggcat cagggaagtc agcatctggt gtatccagtt ggttactata
     7381 ctaaagtcaa acacgttgtt catttactat ttacaattta ctatttacaa tttacgaggc
     7441 gctttttgat ttacaattca caatgtacaa tttataattt ggctgcgctg taattccgca
     7501 tggtaaattg taaattgtca aatcgtaaat ccttttatct gtcaatatct ggtactacat
     7561 aatccaatgt tccgccaatg gcaataaggt cggcgatttt agctccgcgg caaatcgtat
     7621 ttacggtcga taccaatggc aagcccgtac tgcggaaatg caggcggtaa ggcatcttgt
     7681 cgccgtggct ttcgaggaag acgccgaact caccgcggct accttctacg gctgcataat
     7741 aagtgccttc cggtacgcgg ataataggtt tcatcttttc ctggtaggct ccttccggga
     7801 tgttgtctat cagttgctcg ataatcttca ggctctccag aatttcatcc atacggataa
     7861 ggtagcgtgc ccatgaatcg ccttcggtgc ggatgatttc tttaaagtcc accttgtcat
     7921 atacggcata tggcatacgc ttacgcacgt cgcaggccca tccgctggcg cgtccggtgc
     7981 ctccggtagc tccaaaggcg atggcatctt cccgtgagag tatacccaca cctttcagac
     8041 gttgctgggc aatgatgttc ccggtgaata cgtcgtgata ttcgtgtagg ataccgcgga
     8101 ggtaggggat aaactccttc actttcttta cgaagccggg agcaatgtct gcctgcacgc
     8161 caccgatggt gttgtagttc atgatgaggc gtccgccgca agtttcctca aagatgtcga
     8221 gtatcttttc gcggtcgcgg aaaccgtaga agaaggccgt taatgcaccc aggtccatag
     8281 caagacaaga atagaacagc aggtgagagt ctattcgctg caactcgtcc atgatggtac
     8341 gtatgtactg cacgcgttcg cttacttcca cgcccattgc cttttcgata cacatgcaca
     8401 aggcatggcg gttctggtgt gcgcccaggt agtccagacg gtcggtcaga gccaaggtct
     8461 gcggataggt caggctttcg cacatcttct cgataccccg gtggatgtag ccgcagttgg
     8521 catcaatctt gtcgatgatt tcaccctcca atgatacacg gaagcgcatt acgccgtggg
     8581 tggccggatg ttggggaccg atgttcacca catattcctc atcaccgaaa agttgcatct
     8641 ccttattctt gatgctaccg tcgggattca gctccaattc catggtagtg tccaccgttt
     8701 cttcgttgtc catacgcaac ggattatctt tttccggctc attgtcttta cgcatgggat
     8761 agcctaccca gtcattgcgc agatagagtc ggcgcatatc cggatgaccg atgaaaacga
     8821 tgccgtaaaa gtcgtagact tcgcgctcgt tgaaatccgc agctttccag atatcgctga
     8881 cggaaggaag ttcgggatgt tcccggttta gagtggcggt gcgtaccgct atccgttcgc
     8941 cggtaacagt agattccaac agatagacta caccgagtcc gcggggggtg tccggtgcgt
     9001 ctttctcgtc gggtattccc caatccatac cgctgaggca ttccaggaag tccatttgtt
     9061 tctctttccg cagacgcagc atttcgtcgt gcaggactga gggctctatg tattttattt
     9121 ccatattttt aagtactgat tagtggttct cttcttttct gtttactcca ccgaagtatt
     9181 tctctatttt cactttacgc tgcaattgca tcatgccgta gtagaatgct tccggacgcg
     9241 gagggcaacc gggaatgtag acatccactg gcagaatctt gtccagaccg ttcaccacgt
     9301 gataggattt cttgaacggg cctccgctga cggcacagcc gcctacggct actacatatt
     9361 tcggatcggc catctggtcg taaagacgtt tcagaacggg agccatcttg ttggttattg
     9421 ttccgcaaac cataatcatg tctgcctggc gcggactggc acgggctacc tcgaacccga
     9481 agcgcgccat atcgtagcgg gctgcgccga gggccatgaa ttcgataccg caacagctgg
     9541 ttgcaaacgt aagaggccac agtgagttgc tgcgtcccca gttgacgaaa tcgtccagta
     9601 cgccaagggc gacattggcg cctccggcat taagttcccg aaccagtttc tccaacgttt
     9661 cgttgtctgt aaactcctca taagggatag atttaatttt cggtttcttt gttacttcca
     9721 ttccaaagct cctttcctcc aggcataagc aaggcccaga atcaatataa tcaggaaaaa
     9781 taaaacactg aaaagtcctg ccacgccaag ttcgcgggtg atgactgccc aagggaacag
     9841 aaataccgtt tccacttcga acatcaggaa caagatggca aacagatagt aacctacccg
     9901 gaattgcatc cacgatttac cgcgggtagg gataccacac tcgtacggct ccatcttctg
     9961 tgcattgtac gaacggggtg ctatcgcatt ggagagcgcg atgacgatac ccacgaaagc
    10021 gattgccgtc aataagacga ccactaacaa agtaaagttc ataaacctga taagatttta
    10081 gatatataat aatagataca tcgcaccgga ggacaaaacc tctgatttgt tgtccggcga
    10141 ggtcaggggc aagcgtctgc gcttgcaggc cttctaaatg ataatctttc ttagcccgaa
    10201 cacgtaataa ttcgcgtcgg gtacgggatg aggagacaga ttcaacaaac ggtcgcattc
    10261 cggtgcatag gcatgctgct gcatcttgta gatgtacatg cgcaggagta cgcttttgtt
    10321 ggttggtact tgcgtatggt ccacatgttc tatgcagagg gagtttggtg aaaacaagtc
    10381 gtagaacttc tggactgctt gttgggtggt aggagcttgt gacagcgtac agcattctgc
    10441 ttgtcgggtg gcaggaacgc acaaaatatc tgcagctccg gttgcactgt cgtgcaatag
    10501 ggctgcaaag attatgatta aacagtattt aatgcattgc ttcataccac aattctctct
    10561 ttcaaggacg caaagatata ataagtattg ttcaatttgc tatccccgca taacaaaaaa
    10621 tgattatttt tacacttttt atcctaaatc aattccgttt ccagaaatcc ggtgtgaaaa
    10681 gcagcagtac ggtaaataac tcaagacgac ccagaagcat taaaaaggat aacagccatt
    10741 tagctgcatc gggcagggca ttccacgaat aggcaggtcc ggtttcaccc aatccgggtc
    10801 ccatattacc gatactggaa atgacgcagc ccattgattc ttcagccccg acacccatag
    10861 ccatcatgag cagtgtgccg atgactataa tggagatata aataaaacaa aaagccagta
    10921 cggtggagac aatggaggga gagattacct gcttgtttat ccgtaccgga agtatggcat
    10981 tggggtgtag gatgtgtttg aactcgtttc gtgagacttt ggtaagaatt accatacgta
    11041 tacacttcaa gcctccggtg gtactgcctg cacacgctcc catcagcatg atgatggtaa
    11101 gcagccccca caagacgggt gtccattgca tatagtcatc tgtcgcaaaa ccggtggagg
    11161 tctggaggga gattacctgg aacaaggatt tgcggaagga ttcttccatc cccatgggac
    11221 tggtatagta aagcacgatg gctatgacgg cagtgaagag cacaactgaa ccgaaataga
    11281 atttcagctc ggcattgctg atgaacttct tgaatttccg gttgacgaac aataatagca
    11341 aggtgaagtt gttgccggag ataaacatga aaatggagat gacat
//
