LOCUS       gnlProkkaDHOMFEFA_57   12544 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHOMFEFA_57.
ACCESSION   gnlProkkaDHOMFEFA_57
VERSION     gnlProkkaDHOMFEFA_57
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 20:40:25
            Original ID  :: gnl|Prokka|DHOMFEFA_57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 13498
            Orig. end    :: 26042
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12544
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12544
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12544
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(323..1108)
                     /locus_tag="ctg57_13"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(1132..2298)
                     /locus_tag="ctg57_14"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(2311..2880)
                     /locus_tag="ctg57_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             complement(2914..3450)
                     /locus_tag="ctg57_16"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3492..5036)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_17"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5229..5378)
                     /locus_tag="ctg57_18"
                     /transl_table=11
                     /translation="MFTLCHELGLTFEDVAIAIGWLARENKILLRKKEGMLYASIENVE
                     FTFG"
     CDS             5999..6502
                     /locus_tag="ctg57_19"
                     /transl_table=11
                     /translation="MKAKEIGRASIKIEDSSNNMYILSVVVKYRTLTHKAFTAKVIVKG
                     DELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVL
                     DEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFLPLLNTRMNAHPLIQYCFVR
                     XXXX"
     CDS             complement(7131..7418)
                     /locus_tag="ctg57_20"
                     /transl_table=11
                     /translation="MFRCQCGRYELGADFMESYFFHHLYQFFVGLAVGRKFAFRVEEIY
                     FDLVSFFRHHAGDGEGVSAIIARSGKDGDRCFRIPSVSDGFSQRLCGTFH"
     CDS             7422..8564
                     /locus_tag="ctg57_21"
                     /transl_table=11
                     /translation="MIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSGLMGEE
                     NTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETETNYEML
                     EIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTVHAPLC
                     NNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQLEHCQ
                     TPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKACELAHT
                     AKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPAEDAAK
                     IGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8638..9702
                     /locus_tag="ctg57_22"
                     /transl_table=11
                     /translation="MKKFIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9724..10011
                     /locus_tag="ctg57_23"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_24"
                     /sec_met_domain="PF05402 (E-value: 2.4e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.9e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10393..11781)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_25"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
ORIGIN
        1 aagggatgcc acgcatcagg cgacggcgca gcgcttctgc cgacggacga taacgccccg
       61 gatcttttcc gcaacgctta taagcctcac gggtagcagc aatcacaggt tgcaacttaa
      121 tgtctgccat ttgggtggtg gtagtcaagt cttctgtgaa agtatttatt tctttccaaa
      181 gtccatcgca gtaagcagta ttcttcactg ctgcatatac ggctgctccg gcaaaaacag
      241 ggcaggcgtt ctttatttcc tgagatactt ttatttcaaa catactttta ttcaagttta
      301 tatcaactta cgttcaagtc tattatttat gaatcatgat ccccgacaga atccgtccgg
      361 acttaatgcc caaacgcctt gccgagaaaa actcgtcgtg atgaatatac gtacatatcc
      421 gggcaagctc cacttgtccg gacggcacac cgaaagcaag gatttgcatc cggttcgctt
      481 cccacaagtc gatatgatgt tttccggttt cctctttcct gatagaaata cgaggcatat
      541 caaaaccatt cttctgaaat gcttcataca cttcctcacc cacttcaaaa gaagccaatg
      601 agatactcgg accgatacag gcaactacat cttctccact tgtgccaaac tccttttcca
      661 tccgcaacaa agtatcacgc acgatgtatg ctaccgtccc tctccatccg gcatgaatgg
      721 cagctatggc actatgtttc ttatcatata tcaacacagg aacacaatcc gcagtagaaa
      781 tacaaagaca atatcccggc tcgcgggtaa tcaaagcatc cactccgtgc agcatctcct
      841 gtcgttgttg agacgaagcc gataaataag catccccgat cagcaggcaa ttcgtctcat
      901 gagtctgcac aggaatcacc agttcttcgg gtgtctgcga cattccttcc atcagaagcg
      961 tttgattccg ccggaccttt tccgcctcgt ctccactgta gggcgtacag ttgaatgacg
     1021 cataatttcc ttcgctgcac cctccctgcc gggtagttac aaaatgagaa atgttggagt
     1081 atgagcttaa cgactcatac cccaacattc ttttatctct tgtgattgaa atcatttttc
     1141 ttcccaatcc tcttcttcgt attcgtagtc gagatcatca tcgtcgtcgt cagcgtcttc
     1201 ctcatattca tagtcgagtt cttcatcctc gcccatgtcc ttgagttcct gctgcagacg
     1261 ggtcacgtct ttcggacggt gaacaatgtc ttctatctta ttactttcct tgttcagttc
     1321 ctcccacaga atgtctttca acactgagat tcccaaaccg gaaacagaag aaatgaatat
     1381 atgcggaaca ccctcgggca atgtcggttc aatctcgtcc atcagctcct gatcgagcat
     1441 atcgctcttc gtgatagcca gcacacgttg tttgtccagc atttcgggat tgaacgtacg
     1501 cagctcattc agcaatactt catactcctt gcggatatca tcgctatctg ccggaaccat
     1561 gaacaacagc aacgagttac gctcgatatg acgcagaaac cgcagtccca atccttttcc
     1621 ctgactggct ccctcgatga tgcccggtat gtccgccatc acgaatgact ttccatcgcg
     1681 ataggaaaca attcccagat tcggttcgag tgtcgtaaac gggtaatcgg caatcttcgg
     1741 tttcgcagcc gaaatggcag aaagcaacgt agactttccc gcattcggga aacctaccag
     1801 tcctacatct gccaacagtt tcagctccat gatcaccgtc atttcctgca tcggttcgcc
     1861 cggctgcgca aagcgcggag cctgacgggt agccgtcttg aaatgactgt tgccctgacc
     1921 gccacgaccg cctttcagca agatcacttc ctgtccgtcg tccgtcacat cgcaaaggta
     1981 ttctccggtt tcggcgttat acactaccgt tccgcagggt acttcgatca ctttatccgc
     2041 accgtctttt ccgaaactac ggttcttgct gcccgattcg ccatgacctg ccatcgcatg
     2101 acggtcatac ttcaagtgaa gcaatgtcca gtaattacgg ttaccgcgca agataatatg
     2161 gcctcctctt ccaccatcgc ccccatcggg acctccgtta ggacaatatt tctcgcgcct
     2221 catgtgcgta gagcctcttc cgcccttgcc tgagcgacag tatatcttta cgtaatcaac
     2281 aaaattcgat tcagccatat tttttattta ttataatttg tctactgctt cgcagatatc
     2341 agcgaagata ccatccatag tacccagacc gttgatgtgc tggtatttct tttcgttctt
     2401 gtaccagtcg atcagcggag atgtctgtga atgatataca tgcagacgtt ttttgattgt
     2461 ttcttcgttg tcgtcggcac gaccggagtc tttgccacgt ttgatcagac gtaccatcag
     2521 ttcatcttcc ggaacttcga gatccaacat tacagaaaca tcctgtcctc tttccgccaa
     2581 catcttcttt aatgcttccg cctgtgcaat cgttcttggg aaaccgtcga aaattacacc
     2641 tttgctgtct ttgaagctat cgaatacgct tgccagaata tcaatcatca attcatccgg
     2701 aatcaactgc ccctggtcga tgtaaccttt agcagttttg cccagttccg tgccgttctt
     2761 gatttctgca cgcaatacat ctcctgtcga gatgtggttg attccatact tttctacaat
     2821 acgttcgctc tgcgttcctt ttcctgaacc cggagcaccg aaaattacaa tgttcaacat
     2881 ctttttaacc taaaaattaa tttgtatttg aatttaatct actacagtat aaatatcggg
     2941 ataattgcgt ccgaaaccat cataatccaa tccgtagcca acgataaaat cattcggtat
     3001 ttccatcgct acgtattcta tgttcagatt gaccttcagc ttttccggtt tcaccagcaa
     3061 agaggcgata tgaatcgctt cggggttgcg tgtgcccagt gtatccagca gacgctgcat
     3121 cgtcagtccg gtatctacaa tatcttctac gatcactacc gtacgtccgg caatgtcttc
     3181 attcagcccg atcacttctt taattactcc ggtggaagtc accccctgat aagatgccaa
     3241 cttcacgaat gaaatttcgc acggaatcgt aatatgcttc agcaagtcgg cggtaaacat
     3301 gaacgagccg ttcaacacac tgaggaagag cggattctta cctgccaaat cacgattgat
     3361 ttcgttcgct acgcgaatca cttctttttg aatatcctgt tccttaatgg aaacagtaaa
     3421 ttgcttgtct tttatctgta tggtatccat aaccggtcat tttaaaaaag ttgtcgcaaa
     3481 aatacaattt tttattctac cccgtgcatc atcttctgta atttcttcga gagaaggaac
     3541 agaatcagtg aagcaacacc ggacataatg acgaacagca tgaagaagtc atacatggta
     3601 gcaatctgat aaccaaggat tgatttcact tttccgtctt cgggatagag gccactcagc
     3661 atacctgcaa atttatttgc ggtggcggta gaaagatacc agatccccat catcaaggag
     3721 gcgaaacgta acggactcaa cttattaacc atagaaagcc cgataggtga cagagcgatt
     3781 tctcccattg tatgaataaa ataaagtcct gtcagccaga tcatgctcac ctttactccc
     3841 ggaatagcat ctttcactcc aaaacagatg aagagataac caagagaaag cagtaacaga
     3901 ccgattgcct gtttggtagg ggaagccggt tccatgtttc gcttattcag aaagctccat
     3961 ataccgggca taatataggc aaggatcact acaaaaagcg gattgaatga ctggaaccac
     4021 gaagccggca tctcccagcc gaaaatgctg cggtcagtct gttcggaagc gaataatgtc
     4081 agagaagctc ctgcctgctc gtaagctgcc cagaagaaaa tgacgaagaa agctacgata
     4141 tagattacga aaatacggct acgttctact ttggtcaatg aaccatccag cagaatgagc
     4201 actggaaaga caatacaagc cgtaaagata cccacactaa tccagtcatc gctaaaggca
     4261 tagctaaaaa aggctattaa ggcaaccgta agggcagtaa tgatgatgat attacgtact
     4321 ttggtacgtt tgtccatctt cggatgtgaa atatgttcgg ctttatcctc ctttttttca
     4381 cgtctggcgt cggggacgat accaatcggt tcaccggaag gagagaaaag gtatttattc
     4441 ttctgagttt caaagaggac aacagtgaac agcgtcatga ttccggatgc gaggaatccc
     4501 catttaaagt cctgcggatt ccctgtgtct cccaagaaac cgcaaatcaa aggagcggcg
     4561 aaagaaccta cattaacacc catatagaaa atggtgtatg cagcatccaa ccgtttgtcc
     4621 ccgggttcat ataattgccc gacgagcgaa gaaacggtag gcttaaagca accgttacct
     4681 aaaatcatga atccgagccc gccatacatc agccagtggg caaggtctgt attgttcagt
     4741 gaagaggcac tcataaacat caggaactga ccgactgcca tcatcaccgc tccccaaaat
     4801 accgaacgac ggatgcccca atatttatcg gcaatgtatc cgccgatcaa cggagtcaga
     4861 tagaccagtc cggtgtagct accgtagata gaggccgccg cttctttatc aaaaagcaat
     4921 gcctgcgtca gaaagaggat aaagatagca cgcataccgt agtaactgaa acgttctgcc
     4981 gtgctcgttg cgaaaattag gtaaaggcct ttcggatgcc ctttcaatga actcatgaat
     5041 tatgtgttta gtagtttatg gggcgcaaag gtactaaaaa gtagattaaa tgcctcaaaa
     5101 aagaagattc ttatggaata gaaaaataca ggatggcgtg caagaagtct cagttaccca
     5161 ccttattatg ttttcaacag tgtaaataat caagtggata ttctccttaa atgtgggtca
     5221 gtccccattt atccaaaggt aaattcaaca ttctcaatac tggcatagag cattccttct
     5281 ttttttctaa gcaggatttt gttttccctt gccagccaac cgatagcaat cgctacatcc
     5341 tcgaacgtca aacctaactc atggcacaaa gtgaacatag actgttcgcc cttttcattt
     5401 aagatgcgcc atactttccc ggcattcaag ccaattcttt tcttttccat catgcaaact
     5461 ttagaagatt aaacaattta tatttataat ctaaacattg tgagcacagg agaataacgt
     5521 aaagcacatt actgcactac aaagatatca tttttttcga aaaaagcaaa taatcaaagc
     5581 attagctgct attattagtt acattctaat catttatgcc gatctctgct aaaaaatagc
     5641 acaaataaag aaacagttca attctttttc ataagtttgc agacgagaac taaactaata
     5701 tcgcacattt aaaactttaa ttagcatgac taccaaaaaa ctaacaggaa tactttcgtt
     5761 attcctttgt attatttgcc tcgtgagctg taatgacaat gatgacaact tttctccaat
     5821 cactctggaa tatgaagatc ctcaaattaa gttcgacaac gagagccgtt cttacacact
     5881 gactccgttc agcaaagaaa cgacaccact cttcatcaag ggtggagacg gaacttacaa
     5941 agtgaccaat gagaatgaga aagtggtaca agtaaactac cacaacggaa gtttaacatt
     6001 gaaggcaaag gaaataggac gcgcatccat caagatagaa gacagttcga ataatatgta
     6061 tatactgtct gtcgttgtaa aatatcgtac tcttactcat aaggcgttta cagcaaaagt
     6121 cattgtgaag ggagacgagc ttacatctga agaacacact gagttaatga acaaagtggg
     6181 caattcatat ccgattaata aatatgtatt tacttttatg aatgcggaag acagcaaagg
     6241 aacagtagat ttgtattatt cagataataa catgaaaaca ggcaactttg aaaaagaaca
     6301 tatagtgctg gatgaagaaa atgccattcc catcaaaggt gaatacaaat tgagtgagta
     6361 ttatcgtata acaatcaaag aagataatgg caaagttatt gatactttct atattaccaa
     6421 gaactttcta ccactcctca atacaagaat gaatgctcat ccgttaattc agtactgttt
     6481 tgtcagagan nnnnnnnnnt aaccgtacag tacaaacaag attaccttgc actggaaaat
     6541 gcatatctga ttcaaatagc agaatgagaa ctacactgat tttcttcttt agcagagtga
     6601 atagagtatt tattatatga gcaaactccc cattagattt agcaaaaaac aataagctat
     6661 tagctaatca agaatatgcc catagcatat ttatcacaat cacctcttcc acccttttcc
     6721 tgaacctttg ataaataagg cgattgcggg tgaaagaggt gaaccagagg aatatacagt
     6781 agtagaaaca cgcatgggaa ggttaacaaa cagccatgaa tgttctccgg agagagtaaa
     6841 agtaaatgag ataacaatca ttaatatctg acttctcaac tattaataac tgacacatca
     6901 actattaann nnnnnnnnnn nnnnntaata cctgacaact caagtattaa tacctgaagt
     6961 tccttcccaa aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggaac
     7141 gtgccgcaca ggcgctgact aaagccatca ctaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgccagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg actaatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcactgatc aaaccacgcc aacaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcgcgtg
     7861 cctgtctgcg ctcgggagta ggtctgctga ccgtacacgc gccgttatgc aacaacgata
     7921 ttctgcaaac gtccgccccc gaagccatgg tagaaacaga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca
     8041 acgaggaaac ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac
     8101 tggatgccga cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtgacctg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttta tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaacaag gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaacg tcccctacag cagcaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
     9361 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cggaaaaaag
     9481 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgctcat cattatgggc
     9961 gtactgatag gatgtgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatattg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
    10141 ctatcaggtt ccatacagcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggg atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
    10381 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
    10441 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
    10501 catcggcaaa gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
    10561 attcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
    10621 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
    10681 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
    10741 ccaccatata ttcagaatag gaagagcgaa catcgtgtgt acgaaaatca gcatcaccga
    10801 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tataatgaac cgaacaacgg
    10861 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
    10921 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
    10981 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttggtaa tgatatagac
    11041 aatgtctttc atgcggaaag gttcttctgg ttccagtcct tccgcatcca gtgaagcatc
    11101 cagtttctta tcgtagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
    11161 gagacagaac agaataggag cgggaatatt ggtatggaat acgccgctct catccgtaga
    11221 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagtcgttc caatacgcgc
    11281 ggtcgccatt tccagtccca tagcgagagc catctctttg cctttaaacc acttcacgat
    11341 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccgaaaatag cataacccaa
    11401 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
    11461 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
    11521 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
    11581 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
    11641 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
    11701 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgcggagt cattcagctt
    11761 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
    11821 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
    11881 gacatctgac cggatattcc tgtatgaaga agagcagacc gggcccaata ataaagacag
    11941 gcgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
    12001 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
    12061 ctgtcactga attattctgc tgcaggagca ggagtttcag tagccgaagc ttccgttgct
    12121 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
    12181 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagccgca
    12241 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
    12301 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
    12361 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
    12421 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
    12481 gaattagcgt taataatcaa tttctccaaa aatctgattt ggtctgcaaa gtaagcattt
    12541 tttt
//
