LOCUS       c00106_gnlPro..        15195 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLJPBJOP_106.
ACCESSION   c00106_gnlPro..
VERSION     c00106_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:25:19
            Original ID  :: gnl|Prokka|BLJPBJOP_106
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2052
            Orig. end    :: 17247
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15195
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12052:17140]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15088
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15195
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15195
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             43..2304
                     /locus_tag="ctg106_3"
                     /transl_table=11
                     /translation="MSQIPSLISDLAVILISAGLVTLLFKKLKQPVVLGYIVAGILAGP
                     AIKEIPTVTDVESIRIWADIGVVFLLFALGLDFSFKKLMKVGGTAVIGAVTVVIGMMTF
                     GYITGLSLGWGHMNSLFLGGMLSMSSTTIIFKAFDDMGLRNQRFAGVVFGILVVEDLFA
                     VLLMVLLSTLAVSKHVEGMELLDSVIKLGVFLLFCFVVGIYLIPSFLKRARTFLNDETL
                     LIVSIGLCLGMVMIATKAGFSSALGAFVMGSILAETIDAEHIEHIVKPVKDLFGAIFFV
                     SVGMLIDPVLLWEYKIPILILTLVVMVGQILFATFGVLLSGQTVKVAIQSGFSLAQIGE
                     FAFIIASLGLTLKVTDNFLYPIVVAVSVITTFFTPYMIRMAEPAYKIAERVIPASWMSF
                     LERYSSGSNTIRQKSAWDKLLKALVRIVGTYTAVTLVLIFIWLQFVAPFIINQLPGLQG
                     QIISLVLILLLISPMLRAIMMKKNHSVEYQQLWHDSKYNRGPLVSLIVLRIILCIGLVM
                     LPIARLLNTAVGIGLAIAATVIALVIFSKRLKKQSILMERHFFTNLTARELENERNAPI
                     NQRFASHLLERDLHLADFEVKQNSPSMGKTLKELNFRQKCNVNIVTIIRGSKRINIPGG
                     NERLYPFDKLVVVGADDDLAHFRQYIEERYKESLNNLQETKEVNMEQFFISEGSGLIGR
                     TILESGIRDNSGCLVIGIERDARSIKNPPPTTVFEQGDIVWIVGEHEKVLRLSEGKTVK
                     "
     CDS             2333..3091
                     /locus_tag="ctg106_4"
                     /transl_table=11
                     /translation="MKFIGIIPARYASTRFPGKPLADMAGRPMIQRVYEQVKDVLDAVC
                     VATDDSRIEAAVKAFGGNVVMTSDQHRSGTDRVYEAYTKVGQGYDVVVNIQGDEPFIHP
                     EQIETLKACFTDVGTQIATLVKPFRPDDDFETTLFNANSPKVVLNKNNEAMYFSRSIIP
                     YMRGKNYQEWLPNHTYYKHIGLYAYRADTLKEITHLPQSPLELAESLEQLRWLENGYKI
                     KVGITQQETIGIDTPEDMEKALAFLSQQHG"
     CDS             complement(3072..3905)
                     /locus_tag="ctg106_5"
                     /transl_table=11
                     /translation="MDKKEKLLQKRVAGLFALLCVIFFQFFDSDHLFLKEEVVSVASLP
                     EVLVGYWGKPAWLACSMAKVLTSLFVPVGGGAVLITAVLMLEWWASLFILRKFNVGDMA
                     PLYALFPVVMEWGTYCSPYYHLNSILSLVIVLYIFCGYIQIKVKWLSWVTGFILLFAVY
                     CMVGSRLFIFVILVLLYEAEIGEKHWVYWALLLITGTVLPEFLKELYSLSEEQAYQYPQ
                     AWLPAFFPAIMLACVLVATQFKKVRYMQISVWSVSVTSGLLLVLLALTAFSHAVG"
     CDS             complement(4186..6084)
                     /locus_tag="ctg106_6"
                     /transl_table=11
                     /translation="MDKNTLIGFLLIGIVLFAFSWFNKPTPEQLEAQRRYQDSIAQIEL
                     AKQAELQREDSKSTADNSFDSLPDSARDARLKSSFGVFAEAMTGTDDVTVLENDLIELH
                     ISNKGGRISYARLKDYTTYDDKPVILFEGKEASLDFTLVTATNRVLNTADLYFTPVKTQ
                     DPNRLVMRLNTGEGSSLDFIYTVKPDDYMVQFDIKGTSLNGVLAPSTTALDMVWRQKIR
                     QQEQGIKYENRYTALYYKFLSDDVEQLSESKSEDKKVSGRLKWIAYKDKFFSTVMIADE
                     GFESATFDSKMVEADGIVKEFKTTTAVPFDLRGNEATTFRYFFGPNSYPLLKSYDKGVA
                     SDQQLDLERLVPLGASVFRWVNQYFVIPMFDFLGKYIKSYGLIILLMTIIVKLILFPLT
                     YKSYMSSAKMRVLRPQVEELNAKYPGQDKAVERQRATMELYSRAGASPMAGCIPMLLQM
                     PILIALFMFFPSAIELRHQSFLWAHDLSTYDAIFSWNKYIPIITPYFGNHISLFCLLMT
                     ITNVIYTKYNMEMTNTGQQQMPGMKAMMYMMPLMFLVFFNQYASGLTYYYFISTLITIV
                     QTLVFRYTINEDKLLAKLEANKKKPQKKSGFMKRLEEAQRMQQEQLKKQQDQKKKR"
     CDS             complement(6096..7700)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg106_7"
                     /sec_met_domain="GATase (E-value: 2.4e-55, bitscore: 177.3,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VADTKYIFVTGGVVSSLGKGIIAASLGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVPTTRSNNITTGRIYQSVINKE
                     RKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQL
                     KWELGKNCMCVHLTYVPYIAAAKEFKTKPTQHSVKQLQELGIQPDVLVLRTEHLLSNDI
                     TRKVALFCNVDADAVVQSVDVPTIYEVPLVLQRQNMDVTILKKMGLEVGPTPEMKPWKE
                     FLKKKTDATETVKIGLVGKYVELQDAYKSIDESLLQAAIYNDRKLDLHLFHSEKLTEAN
                     AAEQLKDMDGILIAPGFGQRGIEGKFAALKYARENDVPCLGICLGMQCMVIEFARDVLG
                     MTDANSTEMEPNTPFKVIDLMEEQKNITNMGGSMRLGAYDCILKKGSKAYEAYGKEHIQ
                     ERHRHRFEFNSQYREQFEEAGMKCAGENPETGLVEVVEIPALKWFVGVQFHPEYNSTVV
                     NPNPLFVSFVKAAIDNK"
     CDS             7932..9470
                     /locus_tag="ctg106_8"
                     /transl_table=11
                     /translation="MVIKRYFILFSILSLLTNLANAQEVTTITGTNLKDTVQSNAADTI
                     PMIEIEDLDLDNIISLRAQFEKQNQSYSAPVTPNENLLRFLKKDEVELSDEAMYWARLV
                     RDASTIFDANMTFQDTVIADPLFLPLIFKGKLLPKDLSFYDEDAWKNKIDIPQPFIQDT
                     IFKEEVFRQQFREKAQRNIEANHPEYFRYSMRDLPQDKVVAKVIRKPTYQPDLIKVESE
                     ADFSDVDAPVKFIPERRYWTSHFESSLQFAQNYISPNWHKGGVSTLNLTNRELFTYNYN
                     KEKIKFDNSLEIKNNLYTAPKDTLRDYKVGDDVFRIYSNFGYKAFNKWYYTLDLDFKTQ
                     LFSSYAENQNVKLAGLLSPFSINFGLGMKYDLDKTFASSKHKKVTLSANLAPLSYTYVR
                     TLDKDIDLGRHFQKRDGEEEFPYKQSLFGSTVNATMTFQFSRNIIWYSRFYYMTDYKRI
                     QGEFENRLNMAISRFFSTIISLNLRYDDGISKHEDFDSYLQINELLSFGFNYKW"
     CDS             9572..9991
                     /locus_tag="ctg106_9"
                     /transl_table=11
                     /translation="MSESINHNGIIEKIDGNAVFVRIIQQSACSGCHAQSMCSASEKKE
                     KIIEVNDNNPGRFHVNEEVTLCSQSSLGLQAVFLAFVLPLIVVVAAIVAGSCLQWDETT
                     SGLTGLLLLVPYYSILYFLREKLKRKFIFTLKKLN"
     CDS             10001..10966
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 39.1; E-value:
                     3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_10"
                     /sec_met_domain="Fer4_7 (E-value: 7.6e-13, bitscore: 39.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-11, bitscore: 34.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.8e-09, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-10, bitscore: 31.2,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAIGAVFLYAASKKFEVYEDPRIAEVQEALPGA
                     NCGGCGYPGCGGFAAACVKADSLEGLLCPVGGAETMGKVASILGMEAATAEPMVAVVRC
                     NGTCQARPRTNQYDGVKSCAIASSLYGGETNCTFGCLGYGDCESACTFDAIHINLTTGL
                     PEVDEEKCTSCGACVKACPKNIIELRKKGPKSRRIFVSCVNKDKGAAARKACANACIGC
                     GKCVKECPFEAITLENNVAYIDYRKCRLCRKCVAVCPTGAIHELNFPPRKEAAPAVDAD
                     KVKPVTPKAAPAPKAEAPTKVEAAPATAPETITKEETTQK"
     CDS             10979..12310
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_11"
                     /sec_met_domain="Fer4_10 (E-value: 2.6e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.2e-17, bitscore: 52.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7.2e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.7e-32, bitscore: 101.0,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVTNPSNFLVRMGTPISALIEAAGGVPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             12323..13282
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_12"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.2e-120,
                     bitscore: 389.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVVACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLFGKMGGSLGEVSALALLLGLVFMLWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             13315..13920
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_13"
                     /sec_met_domain="FMN_bind (E-value: 3.9e-25, bitscore:
                     78.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FNNKPSEDAYMAVTGDGDSLKIYPATKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSAGPLKVTKDGGNVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             13913..14497
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_14"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-70, bitscore:
                     227.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGLGMGLGFTLALTLLGATRELLGTGKLFGLTLMP
                     EQYGSLIFVLAPGAFIALGYLIAIVNKLRKA"
     CDS             14516..15088
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_15"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.6e-66, bitscore:
                     212.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDKFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALVIFAGIREQLALTRVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             15111..15194
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg106_16"
                     /sec_met_domain="Epimerase (E-value: 1.6e-08, bitscore:
                     24.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYD"
ORIGIN
        1 aaaataaatg tctaactttg ccaaccgaaa aagagtgaaa gcatgtcaca gatcccttca
       61 ttaatttcag acctggcagt aatactgatt tctgcggggc ttgttacttt gcttttcaag
      121 aaattaaagc aaccggtcgt acttggctat attgttgccg gaattctggc aggaccagcc
      181 attaaagaaa tccctaccgt tacagacgta gaaagtatcc gtatctgggc cgacatcggt
      241 gtcgtattcc tgctttttgc cctgggactg gatttcagtt ttaagaaact gatgaaagtc
      301 ggaggcaccg ccgttatcgg agcagtcacc gtcgttatcg ggatgatgac gttcggctat
      361 atcaccggat tgtcgctcgg ctgggggcac atgaatagtc ttttcctggg cggaatgctt
      421 tccatgtcgt ccacgacaat catattcaag gctttcgacg atatggggct gcgcaaccaa
      481 cggtttgccg gagtggtgtt cgggatatta gtggtggaag acttatttgc tgtcctgctg
      541 atggttttgc tttccacact tgccgtcagt aaacatgtcg aagggatgga gttgctcgac
      601 agcgtgataa aactgggggt attcctgctc ttctgttttg tagtcggtat ttaccttatt
      661 ccttctttcc tgaaaagagc acggactttc ctcaatgacg aaaccctgct gatcgtcagt
      721 atcggcctat gcctggggat ggtcatgatc gcgactaaag ccggattttc ttctgcactt
      781 ggcgctttcg tgatggggtc tatccttgct gagacaatcg atgcagaaca tatagaacat
      841 atcgtaaaac cggtaaaaga cttgttcgga gccattttct tcgtttccgt cggcatgctg
      901 atcgacccgg tattactttg ggaatacaaa ataccgatcc tgatactgac actggtcgtc
      961 atggtcggac agatactttt tgccaccttc ggcgtactat tatcgggaca gactgtcaaa
     1021 gtcgccatcc agtccggttt ctcgctggca cagatcggtg agttcgcttt tattatcgcc
     1081 tctttgggac tgacgctcaa agtaacggat aatttccttt acccgatcgt tgtggccgta
     1141 tctgtcataa cgaccttttt tacgccctat atgatacgta tggccgaacc ggcttataaa
     1201 atagctgaac gagtcatccc ggcaagctgg atgagttttc tggaacgtta ttcttctggc
     1261 tccaacacga tccggcagaa aagtgcctgg gacaaactgc tgaaagcatt ggtgcgtatc
     1321 gtcggcacct atacggctgt cacgctggta ctgatcttta tctggttgca attcgtcgct
     1381 ccgttcatta tcaatcagct accgggactg caaggacaaa tcatttccct ggttctgatc
     1441 cttctcctga tctcaccgat gctgcgtgcc atcatgatga aaaagaacca ttccgtagaa
     1501 taccagcaat tgtggcacga cagcaaatat aaccgtggtc cgttggtttc cctgattgtg
     1561 ctccgtatta tattatgtat agggctcgtc atgctgccga tcgcacgcct gctgaacact
     1621 gctgtcggaa tagggctcgc catcgcagcc accgtcatag ccctggttat cttctctaag
     1681 cggttgaaga agcagtcgat cctgatggaa cgccatttct tcacaaacct gacggcacgt
     1741 gaactggaga acgaacgaaa cgctcccatc aaccaacggt tcgccagcca cctgctggaa
     1801 cgcgaccttc acctggctga ttttgaagtg aagcaaaact cccccagtat gggcaagaca
     1861 ctcaaagaac ttaatttcag gcagaaatgc aatgtaaaca tcgttactat tatccgggga
     1921 agcaagcgta tcaacatacc gggaggaaac gaacggcttt atccgtttga taagctggtc
     1981 gtagtcggtg cggatgacga cctggcccat ttccgtcaat acatagagga gcgttataaa
     2041 gaatcgctga ataacctcca ggagactaaa gaggtgaata tggaacaatt ctttatcagt
     2101 gaaggctccg gacttatcgg ccggactatc cttgaatccg gaatacgcga taactccggc
     2161 tgcctggtga tcggtatcga acgagatgcc cgttcaatca aaaacccgcc tccaacaacc
     2221 gtattcgagc agggagatat tgtatggatc gttggcgaac atgagaaagt gcttcgtctc
     2281 agtgagggta aaacagtaaa ataattaact aacgaataaa aacaaccgga gtatgaagtt
     2341 tataggaata ataccggcaa gatatgcctc cacccgcttc ccggggaaac ctttggccga
     2401 catggccggc aggcccatga tacagcgtgt gtatgaacaa gtgaaggatg tactggatgc
     2461 cgtttgtgta gccaccgacg atagccgtat cgaagctgcc gtgaaagcat tcggcggaaa
     2521 tgtcgttatg acttccgacc agcaccggag tggcaccgac cgtgtttacg aagcctacac
     2581 taaagttgga caaggatacg atgtcgttgt caatatccag ggagacgaac ctttcatcca
     2641 tccggaacag atcgagacgt taaaagcatg ttttactgat gtcggcacgc agattgccac
     2701 actggtaaaa ccattccgtc cggacgatga cttcgaaacg acattattca atgcaaactc
     2761 accgaaagtc gttctcaaca agaataacga agcaatgtat ttcagccgtt ccatcattcc
     2821 ttatatgcgc ggcaaaaatt accaggaatg gttacccaac catacgtatt acaaacatat
     2881 cggtttgtat gcttaccggg ccgatacgct gaaagaaatc acccacctgc cccaatcacc
     2941 actggagctt gccgaaagcc tggaacaact cagatggctc gaaaacggct acaagataaa
     3001 agtcggcatc acccagcagg agacaatcgg tatcgacacg cctgaagaca tggagaaagc
     3061 acttgctttt ctcagccaac agcatggctg aacgcagtaa gcgccagcaa taccagtaaa
     3121 agtccggaag tgacagatac agaccataca ctgatctgca tataccggac tttcttaaac
     3181 tgcgtagcca ccaacacaca agccagcatg atagccggga aaaatgccgg aagccatgcc
     3241 tgtggatatt gatatgcctg ttcttctgaa agtgagtaca gttctttcag gaattcaggc
     3301 agcacagtac ccgttatcaa cagcaaagcc caatacaccc aatgcttctc tcctatttcc
     3361 gcctcgtaca acagtacaag gattacaaaa ataaacaacc ggctccccac catacaataa
     3421 accgcaaaca acaaaataaa ccccgtcacc caggagagcc attttacctt tatctgtata
     3481 taaccacaaa atatatacaa aacaataacc aaagaaagaa tagaattcaa atgataataa
     3541 ggactacaat aggttcccca ctccataaca accggaaaca gagcatacaa aggagccata
     3601 tcccctacat tgaatttccg cagaataaat aaagaagccc accattccag catcaacacg
     3661 gccgtaatca aaacagcccc gccaccgaca ggaacaaaca aagacgtaag tactttcgcc
     3721 attgaacaag ccagccatgc aggtttcccc caatagccga ccaacacttc cggcaaactc
     3781 gcaacactta ccacctcttc cttcaggaac aaatgatccg aatcaaaaaa ctggaaaaag
     3841 ataacgcata gcaatgcaaa gagtccagct accctctttt gcaaaagctt ttctttctta
     3901 tccatcagtg aactattttt atacctatta aactcaaaac gtaaagccgg tacttgctat
     3961 tcctaccgga taagtcgtca acgtaagcat aatcatcaat agttgactta tatatcaata
     4021 gtgcaaatat ataaatattt taatacaacg cacgccacat ttcttcaaat tcaagcgatt
     4081 gtacaaaata tacaacttat tgcgcaatcc ggacacaaaa aaggcgtgcc tgagtctttt
     4141 ccggaccggc acgcctctct tttatttatc ttgcagaaaa agctgttatc ttttcttttt
     4201 ctgatcctgt tgtttcttca actgctcctg ctgcatacgc tgcgcttctt ccagacgttt
     4261 catgaaacct gatttcttct gaggcttctt cttgttggct tccagcttag ccagcagctt
     4321 atcttcatta atcgtataac ggaacaccaa tgtctgaaca atcgtgatca gcgtagaaat
     4381 gaagtaatag taagtcagac ccgatgcata ctggttgaag aataccagga acatcagcgg
     4441 catcatatac atcatcgcct tcatacccgg catctgttgc tgtccggtat tggtcatttc
     4501 catattatac ttggtataga taacgttggt gattgtcatc agcagacaga acaaactgat
     4561 gtggttacca aaatacggag tgataatagg aatgtatttg ttccaactga aaatagcatc
     4621 gtatgttgac aaatcgtgcg cccaaaggaa actctggtga cgcagttcga ttgccgacgg
     4681 gaagaacatg aacaaggcga tcaaaatcgg catctgcaac agcatcggga tacaacctgc
     4741 catcgggctt gccccggctc ggctatacaa ttccatagtt gcacgctggc gttccaccgc
     4801 tttatcctgt cccggatatt tggcattaag ctcttccacc tgtggacgaa gcacacgcat
     4861 cttcgctgac gacatatatg atttatatgt caacgggaat aaaatcagtt tcacgataat
     4921 cgtcatcaac aggatgatca gaccgtaact cttgatatat ttacccagga agtcaaacat
     4981 cggaatgacg aaatactggt tcacccaacg gaagacactg gcacccagcg gaaccaagcg
     5041 ttccagatcc aactgctggt ccgaagcaac ccctttgtca tacgatttca gcaacggata
     5101 gctgttcggt ccgaagaaat aacggaaagt cgttgcctca ttgcctctca ggtcaaaagg
     5161 aacggctgtt gtagtcttaa actctttaac gataccgtct gcctcaacca tctttgaatc
     5221 gaaagtggcg ctttcaaaac cttcatcggc aatcatcacc gtcgagaaga atttatcttt
     5281 ataagcaatc catttcagac ggcccgacac cttcttgtct tcgctcttgc tttcgctcag
     5341 ctgctccaca tcatcggaca ggaatttata atacaaggca gtatatctgt tttcatattt
     5401 gataccctgt tcctgctggc ggattttctg acgccatacc atatccaaag cagtcgtact
     5461 cggagccagg acaccgttca ggctcgttcc cttaatatcg aactgaacca tataatcgtc
     5521 cggcttgact gtatagataa agtccagtga actgccttca cctgtattca gtcgcatcac
     5581 caaccggttc gggtcctgtg ttttcaccgg agtgaaatac aggtcggctg tgttcaatac
     5641 gcggttggtt gctgttacca gggtaaagtc aagcgaagcc tcttttcctt caaacaggat
     5701 gaccggctta tcatcatacg ttgtataatc cttcaggcgg gcatatgaaa tacgtcctcc
     5761 cttattactg atatgcagtt cgatcagatc attttccaaa acagttacat catctgtacc
     5821 tgtcattgct tcagcgaata caccgaaact gctcttcagc cgggcatctc tcgcagaatc
     5881 cggcaagcta tcaaaagaat tatcggcagt gcttttgctg tcttcgcgtt gcaactccgc
     5941 ctgtttagcc agttcgatct gagcgatcga gtcctgataa cggcgctggg cttccaactg
     6001 ctcaggcgtc ggtttgttaa accagctgaa tgcaaataaa acaataccaa taagcagaaa
     6061 accaattaat gtgtttttat ccatctataa cgttgttatt tattatcaat agcggctttc
     6121 acaaagctca cgaaaagtgg gttcggatta actaccgtac tgttgtattc cggatggaac
     6181 tgaacaccaa cgaaccattt caacgcagga atttctacca cttccaccag accggtttcc
     6241 ggattctcgc ctgcacattt catgccggct tcttcaaact gttcgcgata ctggctgttg
     6301 aattcgaaac ggtggcggtg acgttcctgg atatgttctt ttccataagc ctcataggct
     6361 ttggaacctt tcttcaggat acagtcgtaa gctcccagac gcatagaacc tcccatattg
     6421 gtaatgttct tctgttcttc catcaggtcg atcaccttaa acggcgtatt cggctccatc
     6481 tcggtcgaat tggcatccgt catacccaaa acgtcgcggg caaattcaat caccatacat
     6541 tgcataccca ggcagatacc caggcaaggc acatcatttt cgcgggcata tttcaaggca
     6601 gcgaactttc cttcgatacc gcgctgtccg aatcccggag caatcaggat accatccatg
     6661 tccttcaact gttcagccgc attggcttca gtcagttttt ccgaatggaa caaatgaaga
     6721 tccagtttgc ggtcgttgta gatagcagcc tgcaacaatg attcgtcgat tgacttataa
     6781 gcatcctgta attccacata tttaccaacc agaccgatct taactgtttc ggtagcatcc
     6841 gtctttttct tcaggaactc tttccagggt ttcatttccg gagtcggccc tacttccagt
     6901 cccatctttt tcaggatagt tacatccatg ttctgacgct gcaataccag cggaacttcg
     6961 taaatagtag gaacgtcgac cgactgcact acagcgtcgg cgtctacgtt acagaacaaa
     7021 gcaaccttgc gggtaatatc attactcagc aaatgttcgg ttctcaagac cagtacatcc
     7081 ggctggatac ccagttcctg caactgtttt acagaatgct gtgtaggttt cgttttaaat
     7141 tctttcgcag ctgcgatata aggtacataa gtaagatgta cgcacataca gttcttaccc
     7201 agttcccatt tcagctggcg aacgctttcg atgaaaggca gcgattcgat atcgcctact
     7261 gttccaccga tttccgtgat cacaaaatca aacttgtact tcgatcccag cagcttcaca
     7321 tttctcttga tctcgtcggt gatatgagga acaacctgca cagtcttgcc cagataatcg
     7381 cccttgcgtt ccttatttat cacactctga taaatacgac ctgtcgtaat attgttcgag
     7441 cgtgtagtcg gaacattcag gaaacgttca taatgtccca ggtccaggtc cgcttcatgt
     7501 ccgtctacgg ttacataaca ttcaccgtgc tcataagggt tcaatgtacc cggatcgata
     7561 ttaatgtagg ggtcaaactt ttggatagta accttgtaac ctctcgcctg aaggagttta
     7621 cccaatgatg cagcaataat tcccttacct aaagaagaga ctacgccgcc cgtaacgaag
     7681 atgtactttg tatctgccac gatagtaata ttttaattgt ctttaattgc tcactcgcat
     7741 ttcaaaactg caaagttagt cattttcatt cagacagcaa gtgtctcgga tattttttca
     7801 aagcacattc atccgcattc cggtttccct attagttcag attgttatat gatgtgaaag
     7861 attagtagat ttcatacttt ttatctaatt tcgcaccgta gatacttata gattgtaaat
     7921 aaaaaggaat tatggttatc aagagatact tcattctatt ttctatactt tcattattga
     7981 caaacctggc aaatgcacag gaagtgacaa ctattaccgg aaccaatctt aaagatacag
     8041 tacagagtaa tgcggctgat actatcccaa tgattgaaat cgaagatctg gacctggata
     8101 atatcataag cctgcgggca caattcgaga aacaaaacca gtcatattct gcaccggtca
     8161 caccgaatga aaatctgctt cgcttcctga aaaaagacga agtggaactg tcggacgaag
     8221 ccatgtactg ggcacgtctg gtgcgcgatg cttccactat cttcgacgcg aatatgacat
     8281 ttcaggatac agtcatagca gacccgctgt ttttaccgct catattcaaa gggaaactcc
     8341 ttccgaaaga tctttccttc tacgatgaag atgcatggaa aaataaaatc gatatcccgc
     8401 aaccttttat tcaggacacc atatttaaag aagaggtgtt cagacagcag ttccgcgaga
     8461 aagcacaaag aaatatagaa gccaaccatc ctgaatattt ccgttattca atgagggatc
     8521 tacctcagga caaagtagtt gccaaagtga tcagaaagcc gacctaccaa ccggacctga
     8581 tcaaggtaga aagcgaagca gacttcagtg acgtggatgc accggtaaaa ttcattcccg
     8641 aaagacgtta ctggacgtca catttcgaaa gttctttaca gtttgctcag aattacatct
     8701 ctccgaactg gcataaaggg ggtgtaagta cgctgaacct gaccaaccgc gaactgttta
     8761 catataatta taataaggaa aagataaagt tcgacaattc actggaaata aagaacaacc
     8821 tgtataccgc tcccaaagat actttgcgcg attacaaagt cggagatgac gtgttccgta
     8881 tctacagtaa ctttggttat aaggcattca acaaatggta ctacacactg gatcttgact
     8941 tcaaaaccca gcttttcagc agttatgccg aaaaccagaa cgttaaactg gccggactgc
     9001 tctcaccttt cagtattaat ttcggtcttg gtatgaaata cgacctggat aaaacgttcg
     9061 cgtcgtccaa acacaaaaaa gtaacgttaa gtgccaacct tgcaccgtta tcttatacgt
     9121 acgttcgtac attagataaa gacatcgacc tgggccggca tttccaaaag agagacggag
     9181 aagaagagtt tccttacaaa caaagcctgt tcggttctac cgtcaacgca actatgacat
     9241 tccagttcag ccggaatatc atctggtatt cgcgtttcta ttacatgaca gattataagc
     9301 gtatccaagg tgagttcgaa aaccgtctga atatggcaat aagtcgattc ttctcgacta
     9361 tcatctcgct gaacttacgt tatgatgatg gtatctccaa gcatgaagac ttcgacagct
     9421 acttacagat taacgagttg ttgagctttg gctttaatta caaatggtaa gctgaacacg
     9481 attatttctg taataaactt tgttaatcgt gacataatat ccaaataatc cttacttttg
     9541 cccctgattt tgcaatgtcg agattacaaa catgagtgaa agtatcaatc acaacggaat
     9601 aatagagaag atcgatggca atgcggtctt tgtcagaatc attcaacaat cggcctgctc
     9661 cggttgccac gcacaaagca tgtgcagcgc atctgaaaag aaggaaaaga tcattgaagt
     9721 gaacgacaat aaccctggca gattccatgt gaacgaagaa gtaaccctat gtagccagag
     9781 ttcgctcggt ctgcaagcgg tttttttggc ctttgtgctt cctctgattg ttgtagttgc
     9841 ggcgattgta gcaggaagct gtttgcaatg ggacgaaaca accagcgggt taaccggtct
     9901 attactacta gttccctact acagtatatt atacttttta cgcgagaaac tgaaaagaaa
     9961 atttatattt accttgaaaa aacttaattg atcaaatatc atgattttaa ttgccgttat
    10021 ttcattagga gccattggag ccatcggcgc agtattcctc tacgccgcct ccaagaagtt
    10081 tgaagtatac gaagatcctc gtatcgcaga ggtccaggag gcattgcccg gagccaactg
    10141 cggaggttgc ggttaccccg gttgcggtgg gtttgcggca gcctgtgtaa aggccgattc
    10201 actggaagga ctgctttgtc cggtcggtgg cgccgaaaca atgggtaagg tcgcatccat
    10261 cctcggtatg gaagctgcta cagccgaacc aatggtagca gttgtccgtt gtaacggaac
    10321 ctgccaggcc cgtccgcgca ccaaccagta tgatggcgta aaaagctgtg ccatagcatc
    10381 ctctttgtac ggaggcgaaa cgaactgtac gttcggttgc ctgggttacg gcgactgcga
    10441 aagtgcctgt accttcgacg ccatccacat caatctaacg accggactac cggaagtgga
    10501 cgaggaaaaa tgtacttcat gcggagcctg cgtcaaagct tgtccgaaaa acattatcga
    10561 actgcgcaaa aagggaccga aatcacgccg tatcttcgtc agctgtgtaa acaaagacaa
    10621 aggagctgct gcccgtaaag catgtgcgaa cgcttgtatc ggttgtggta aatgtgtgaa
    10681 agaatgtccg ttcgaagcaa tcacgctcga aaacaacgtg gcttatatcg actaccgcaa
    10741 atgccgtctg tgccgtaaat gcgtagcagt atgtccgacc ggagcaattc acgaattgaa
    10801 cttcccgccc cgtaaagaag ccgcccctgc tgtggacgcc gacaaagtaa agccagtaac
    10861 gcctaaagct gcaccggccc ctaaagccga agcaccgaca aaagtcgaag ctgcaccggc
    10921 aacagcgcct gaaacaataa caaaagaaga aacaactcaa aaataaaaat ctaatagtat
    10981 gctaaggaca tttcgaatcg gaggtataca tccacccgaa aataaattgt ctgccgggaa
    11041 gaaaataacc ggactggcta tacccaagca ggttattata ccgctaagcc agcatatcgg
    11101 ggctcctgcc caggctgtgg taaagaaggg tgatacggtt aaagtaggta cgcttctcgc
    11161 caaagccgga ggttttgtat cggcgaatat ccactcgtcg gtatccggta aagtaaacaa
    11221 gatagataac gctctcgacg caagcggata caaacgtccc gctatctata ttgatgtgga
    11281 aggtgacgaa tgggaagagt cgatcgaccg cagcgaaacg ctcgtgaaag agtgcccgct
    11341 tccttccaaa gagatcgtag acaagatcgc cgcagccggt atcgtgggtc tgggtggtgc
    11401 gacattcccc acacaggtca aactgatgcc gcctcccgga agcaaagccg agatcatcat
    11461 tatcaatgcc gtagaatgtg agccgtatct gacttccgac cattcattga tgatggagaa
    11521 ggcagagcag attctggtcg gcgttacgct gttgatgaaa gctgtaaatg taacaaaagc
    11581 agtgatcggt atcgaaaaca acaagcctga cgccatcgct catctgagta aactggctac
    11641 agcctataaa ggtatcgaga ttatgccgct gaaagtacag tatccgcaag gaggtgaaaa
    11701 gcaattaatc gatgctgtga ttcgtcgtca ggtgaagagc ggtgcactgc ctatttccgc
    11761 cggagctgta gtacaaaatg taggaactgc ttttgcagtg tatgaagcgg taatgaaaaa
    11821 caaacctttg tttgaacgcg tcgttaccgt gacaggtaaa gcagttacca atccttccaa
    11881 cttcctggtc cgtatgggta cgcctatcag tgcactgatt gaagctgccg gtggtgttcc
    11941 tgaaaataca ggaaagataa tcggtggcgg cccgatgatg ggaaaagccc tgattgctcc
    12001 ggaagtaccg gtaacgaaag gtagttcagg cgtattgctc ctgacaaaag aagagtctgt
    12061 ccgcaaaccg atgcgcgact gtatccgctg tgccaaatgt gtcagcgttt gtccgatggg
    12121 cctcaaccct accctgctga tgaatgcaac agaatttgca gaatgggatt tggccgagaa
    12181 gaattatatc accgactgta tcgagtgcgg ttcttgtagt tatacctgcc cggccaaccg
    12241 tccgttgctg gattatatcc gttcgggtaa aggaaaggta atgggtatca tacgggcacg
    12301 aaagtcataa aaacagagca atatggaaaa taatttaata gtatctcctt cgccccatat
    12361 ccacggcggc gatagcataa gcaaaaatat gtatggtgta ctgattgccc ttgttccggc
    12421 tttcctggta tccctctact acttcgggct gggtgcgctg atcgttactg caacatcggt
    12481 cgtagcctgc gtcctctttg aatatctgat ccagaagttc ctgatgaaaa aggaaccgac
    12541 cgtatgtgac ggttcggcta tcctgaccgg tgtactgctg gcattcaacc tgccgtcgaa
    12601 cctgcctgta tggatcatcc tgatcggtgc actggcagca atcggtatcg gtaagatgtc
    12661 atttggcgga ctgggtaaca atatttttaa cccggcatta gtcggacgtg tattcctgct
    12721 gatctctttc ccggcacaga tgacgatgtg gccggaagtc ggacagctga cagcctacac
    12781 cgacgcaacc accggtgcaa ctgttttatc actgatgaac gaaggggcac tcgacaagtt
    12841 gcctaccctg gtagatatgt tgtttggtaa aatgggcggc agccttggtg aagtaagtgc
    12901 actggcattg ctgctgggac tcgtctttat gttatggaaa aagattatta cctggcagat
    12961 tccggtttct atcctgctga ccgtatttgt attcacaggt attatgcatc tggttaatcc
    13021 ggtacaatac gcaagtccgt tcgttcacct gctgtcggga ggtctgatgc tgggagccat
    13081 ctttatggca accgactatg tgacttcgcc catgagtaag aacggtatgc tggtttacgg
    13141 tgtcggtatc ggtattctga ccaccgttat ccgtctgttt ggttcttatc cggaaggtat
    13201 gtcgtttgct attcttatta tgaatgcatt taccccgctg atcaacagtt atatcaaacc
    13261 taaacatttt ggagggaaat aagcatggca aaactaaaat caacattacc caatatgctc
    13321 ttgtcgctta ccatcatctg tttggttgcg ggagcgatat tagccggagt aaatatgtac
    13381 actaccggcc cgatagcagc ctccaaagct gctgcgctgg aagctgctat caaagctgtt
    13441 acacctgaat tcaacaacaa accgtcagag gacgcttata tggcagttac aggcgacggc
    13501 gattccctga aaatctatcc ggctaccaaa ggcggagagt tcgtaggtgc agctgtcgaa
    13561 agtaatacaa aaaaaggatt cagcggagag atcaaagtga tcgtcggatt cgataaggaa
    13621 ggcaagttat tgaactattc cgtattacag catgcggaaa ctcccggtct gggagctaaa
    13681 atgcaggaat ggttcagtac ggacaagaat aaacaaagcg ttttgggacg cagcctgtcc
    13741 gccggaccat taaaagtaac taaagacggt ggcaacgtgg atgctatcac agcagcaacc
    13801 atcaccagcc gtgcatttct ggatgcggtg aaccgtgctt acagcgcatt cgccggaact
    13861 gacggagtaa ccggtgcaac aaccgctaac actaacgagg gaggaaacga caatgagtaa
    13921 tatgaaagta ttgatgaacg gtatcatcaa agagaacccg acatttgtct tgttgctggg
    13981 tatgtgtcca actctgggaa caacttcttc agcattgaac ggtatgagta tgggactggc
    14041 aaccatgttc gttctgatct gttccaatat ggttatttca gccttgaaga acctgatccc
    14101 cgacatggta cgtattccgg cctttattgt cgtaatcgct acattcgtaa ccgtcgtgca
    14161 gatgtgcatg gaagcattcg ttccggctct ttacgccagc ctgggattgt tcatcccgct
    14221 gatcgttgta aactgtatcg tgttgggacg tgcggaagca tttgccgcta aaaacggagt
    14281 gatcccttcc gcattcgacg gattaggtat gggactcggc tttacgctgg cacttacctt
    14341 gctcggagct acccgcgaat tgctgggaac aggtaaactg ttcggcctga cactgatgcc
    14401 cgaacaatat ggttcgctga tctttgtatt ggctccgggt gcctttatcg cgctgggtta
    14461 cctgattgct attgttaata aattgcgtaa agcctgatat taaaaaacga aagatatgga
    14521 atatatacta atatttatcg cagccgtatt cgtcaacaac gtagtgttgg cgcagttcct
    14581 gggtatctgt ccgttcctgg gcgtatcgaa aaaggtggaa acggcagccg gtatgggtgc
    14641 agcagtaaca ttcgtgttga cgatcgcaac catcgttact ttcctggtgc agaaatatat
    14701 cctggataag ttcggactgg gctttatgca gaccatcagc tttatcctga tcatcgccgc
    14761 gctggttcag atggtcgaga tcatcctgaa aaaggtttct ccggctcttt accaggcact
    14821 tggtgtattt cttccgctga tcaccaccaa ctgctgtatc ctaggtgtcg ccatcctcgt
    14881 aatacaaaaa gaatataatt tattggaatc tgttgtatat gcaatatcaa cagctattgg
    14941 atttgcgcta gctttagtta tctttgcagg gataagagaa cagttggctt tgacacgtgt
    15001 tcccgaaggt atgaaaggta cccctattgc gctgataaca gccggtttac tggcaatggc
    15061 gtttatggga ttctccggaa tcgtataatt taatctaaat agagactagc atgaaaaaga
    15121 aaatcttagt agcaggtgga accggatata ttggctcaca cactacagtt gagttgcaga
    15181 atgcaggtta tgatg
//
