LOCUS       c00081_gnlPro..        15535 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GOCHANPE_81.
ACCESSION   c00081_gnlPro..
VERSION     c00081_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:58:08
            Original ID  :: gnl|Prokka|GOCHANPE_81
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15535
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..360)
                     /locus_tag="ctg81_1"
                     /transl_table=11
                     /translation="MKSVKLASILFYLNSVFVVSCFVSCGSSPTEASSLLTADIRGGMD
                     KPGLLGLGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDRQG
                     PLSSPASELSYHKPFH"
     protocluster    1..15535
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2070:5535]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2071..5535
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15535
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15535
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(470..1948)
                     /locus_tag="ctg81_2"
                     /transl_table=11
                     /translation="MGEVRACAPTHEIMRKEKAFLMNNLYTFAYMRKDLNGARHFSIGI
                     KFTILLFTIAILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVTDINGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPS
                     LALECYLRALEYEGGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDT
                     AGQGRILEEVKKYEALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQER
                     YLYAFIIGIILFICFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQIAL
                     LEKRITKMKEEKDQELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFH
                     DRDAGKIVSEDWELLEVLLNKAYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTETFVEFISSF"
     CDS             2071..2763
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-74, bitscore:
                     239.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGAAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             2812..4755
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.2; E-value:
                     1.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-61, bitscore:
                     197.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-38, bitscore:
                     122.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVHGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFNEAEKNIQARINKLMSIKGKESVDSIHKRLGHI
                     MWEHIGMARNAESLKEAIQMLKDLKKEFWSNVFIPGNADDLNVELEKALRLADFIEIGT
                     LMAHDALDRAESCGGHFREEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             4780..5535
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_5"
                     /sec_met_domain="Fer2_3 (E-value: 8.9e-26, bitscore: 80.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.1e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDINITLKVWRQKGPNVKGQFETYQLKNINQGTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKPDAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             5958..7169
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_6"
                     /sec_met_domain="Radical_SAM (E-value: 9.1e-17, bitscore:
                     51.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             7203..8435
                     /locus_tag="ctg81_7"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHKVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNIDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(8450..8542)
                     /locus_tag="ctg81_8"
                     /transl_table=11
                     /translation="MKKPRCKYTELLLFVNGLSAKLCFVTCNKI"
     CDS             complement(8641..11778)
                     /locus_tag="ctg81_9"
                     /transl_table=11
                     /translation="MIRNIINLKAIILYFGLILCLIAGMPTPAYGSFSYPVKDESYVLV
                     INSYVDGERWSGNLLNMISKFATPEEYTLRIDHMSVMLVDTPEKLKEKQEAFFEVNKKK
                     PDGIIYLGVNGWAFMRDKIREKWGDIPTLVCSETGEMAEDECYFNQRHSSDRVIPLQEA
                     VKGYNATGLVIPYYVKGSIDLVKELIPGLRRLIFISDRRYVSTWLRDEMEKHMETSFPE
                     GKVDFYTEGSCSMDSLLAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGI
                     SRHPVFSLYDMGVEEGYTIGGYYNSAKTIETALIPLLQQVYNGEDMGKIPVSTVNDPHK
                     YLNYASLISAISNEDNFPRDAIYLNAPPSFLEKYWMQLLGFLIFFLVVVFLAWHYVYRS
                     KQKMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFV
                     VNKRGKEIANLIGGSYPLLLSAVPTVLESGKSFTYEYYFEPTGLYYTIIIMPTSEENVV
                     DAFFIDITDIHKFQTHLKAMNHKLAMALEAADLLPWRYNLAEGKIIYESKVHPGDNIET
                     AEVHTHEVSLKEYFSKIHPSFRACVEKAFDDLCNGKIKKVRKEYCLERLIPGEDRHEWE
                     EIQVMAEYDASGKPKALIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEI
                     RTPLNAIVGFSNILASTDDLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTY
                     DYVDINAVLRDLEQSAHLKNKNPDVQISFKDYLEPCVIYTDRNRLSQLMINLLNNAMKF
                     TQAGSILFGYKLKDDNTLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICE
                     MIVTQMKGTIGVDSMEGKGSKFWFTLPFQPKKELFPSEEQKPVTLEKIARSEVTILIAE
                     DNSSNYRLFESILKPEYKLIHAWNGKEAVELFHQHKPQLILMDIKMPVMDGYEATAEIR
                     KVSASVPIIAVTAYAFAQDEQRIINSGFDAYTAKPINGKILKDKISTLLTHRIILM"
     CDS             12009..12785
                     /locus_tag="ctg81_10"
                     /transl_table=11
                     /translation="MELMDMKDYDIDFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPS
                     LFDLLVSWPMLLVVSGIFMIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRIYWPLGL
                     ILLGLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHI
                     VLDPVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVDS
                     FLAGCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     CDS             12793..13587
                     /locus_tag="ctg81_11"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGQGSLLLLLAIAIQCALLTLYGDLPLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIGRQMEEKTAPPPTTVPEEILDRISVK
                     DGTRIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             complement(13925..14443)
                     /locus_tag="ctg81_12"
                     /transl_table=11
                     /translation="MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQM
                     LVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGSFINGEVFDDRSFEAG
                     EPAELTVSDMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFD
                     LEVTRIVKE"
ORIGIN
        1 atggaacggt ttgtgatatg atagctcaga tgctggagaa gaaaggggtc cttgccgatc
       61 gaacaggacg atacggggct cttttacggg aagcacatag atatatcgat ctgtcacggc
      121 ataatcataa actccgtcta tcaacgaggc atcatccgtg gtcacctcta aagggacaaa
      181 agtaaccccc ttgatctcat cgcctaatcc caatagcccc ggtttatcca tcccccctct
      241 tatatccgca gttaaaagag aggacgcttc cgttggcgaa gaaccgcatg acacgaaaca
      301 agaaacgaca aaaacactat ttaaataaaa caagatagag gctaacttta cacttttcat
      361 aaccatgctt ttttgcctcc aaaaatatcc cgcatatctc acaaatcaca tgataaatga
      421 gaacaaaaat gagaacaaac ctgccaagac cgctataaat acataataat caaaaacttg
      481 agataaactc cacaaatgtc tccgtagaac cttctttctt aaaaatcttc cggaatagac
      541 gaggacgaag taccgaacta ttatatttca atacccgtgt gatctggttg gcgggaacgc
      601 cgatcttcgt aagcatacag accttcaact ccgtatcgga aatagcagga tatagttttt
      661 tcagccgtaa ggtaaagtca tcataagcct tattcaacag cacctccaaa agctcccaat
      721 cctcagagac aatcttgccg gcatcccgat cgtgaaactt ctcatagacc tccgatttcc
      781 gcaagatcgc aacagataat aaatgcttac tctccttatt atgaatcgac tcgttacaaa
      841 tctccagccg ttgtttttcc aattgtaagg aaaccaacat caactcttga tccttttctt
      901 ccttcatttt cgtaattctc ttttccaaga gggcgatttg ccgttcattc tcttcttttt
      961 cttctcgcat acgttgttgc tggctagcaa tcgagcgtcg caaggcttct tcccttcgaa
     1021 gagcgttttc ctgcgtattt ctccatcgcc gataaaggag gaagcaaata aatagaatta
     1081 tgccgataat aaacgcgtac agataacgct cctgtcccct ttgcgatagc atcaattctt
     1141 tcctatacaa gtcctcacga accggcctta catcataccg ggaagtgatc tgataaatcg
     1201 attctctcgc tgacagcgat ccgatagaat cccgtaacgc ctcgtatttc ttgacttcct
     1261 ccagtatccg gccttgtccg gccgtatcat tcaagagctg atattgggca ctcgcttttc
     1321 tcaaaaaaga catggccttg ccatataatt cctgctcggc gtacagcctt cctatctggt
     1381 tatataaccg tccccaaaat tcgtaatccc aattccctcc ctcatattcc aacgcacgta
     1441 aatagcattc caaagctagg gacggttgat ccatatcctc atagactttc ccccggtaaa
     1501 accacgcttt gggaggccag taacagcctc gtgtcgtcct ataataatcc gtagcgatag
     1561 agattatgga atccgatgta tgcctcaatc ccgcctcatc ccgtgattcg gtccataaca
     1621 gacaataacg ggctttctct cgaagcgata atccattgat atccgtcact ttctctaata
     1681 acaccaaagc gctgtccgga tgatgcggaa tcaatttctc tacctgccag aacaggttgc
     1741 catgcttgtc gctcctatac gaaaaaagca caagaaccaa gatcgcgatc gtaaacaata
     1801 agatcgtaaa cttgatccct atagaaaaat gccgtgcccc attcaaatcc ttacgcatat
     1861 aggcaaatgt atataaatta ttcataagga aagccttttc cttccgcatt atttcatgtg
     1921 tcggggcaca tgccctgacc tctcccatta atgcagaaat atttctttaa tcgtttgcgc
     1981 gatatatgga tttagcatac ctttgcgtga taattacata gtttaagtag aaatttctaa
     2041 atacaattaa ataacttaaa ttattatctt atgtggttac ttaattcttc tatcgggaag
     2101 aagctgataa tgagtatatc aggcctcttt cttgttctgt tcttattgtt ccacctgtcg
     2161 atgaacgtgg cggccgtttt ctccggagag gcttataaca tggtttgttc gctgttgggc
     2221 tctaattggt acgctgtggc agctactctc gtattggccg caggcgttgt gatccacttc
     2281 gtgtacgcta tcattcttac cttgcaaaac cgtaaggcac gtggtaacga ccgttacgct
     2341 atcaacgctc gtccgaaagg cgtggaatgg gcatctcaga acatgttcgt tttgggtttg
     2401 atcgttatcc tgttcatgct gttgcacttc agccagttct ggtataagat gatgttcgcc
     2461 gaattgatcg gtcatcacga agtagcattg ggggcagcta tggtatctcc acaagacgga
     2521 gccgctttta tcaactatta cttccaaggt aatgccgtga tcaccgttct ttatttgatc
     2581 tggtacgtgg ctttgtggtt ccacttgact cacggtttct ggagcgctat ccaaacaatc
     2641 ggttggaata acacgatctg gatgaaccgt tgggaatgta tctctaagat cgtagctacg
     2701 gttatttgcg gacttttcgc gatcattact atcatcttct tcctaaacgg agtaggtgct
     2761 taattgcaag ctacaggttt tataattaag aacttttgaa attaaatcat tatgtctgaa
     2821 ataaattcta aaatacctca aggcccgttg gctgagaagt ggactaatta taaaaatcac
     2881 cagaaattgg tgaaccccgc taacaagcgt cgtttggatg ttatcgtagt cggtacaggt
     2941 ttggctggag cttccgctgc cgcatctttg gcagagatgg gattcaacgt attgaacttc
     3001 tgtatccaag attctccccg ccgtgcgcac tctatcgccg ctcaaggtgg tatcaacgcc
     3061 gctaagaact accagaatga tggtgactct gtttaccgtt tgttctacga tacgatcaaa
     3121 ggtggtgact accgtgctcg tgaggctaac gtttatcgtt tggctgaggt ttctaactca
     3181 atcatcgacc agtgcgtggc tcaaggcgtt cctttcgctc gcgaatatgg tggtttgttg
     3241 gataaccgtt cattcggtgg cgctcaggta tcgcgtacgt tctacgcccg tggccagacg
     3301 ggtcagcagc ttttgttagg cgcttattca gcgttgagcc gtcagatcgg tttgggtaag
     3361 gttaagatgt acactcgtca tgagatgttg gatgtagtta aggtagacgg tcgtgctcgt
     3421 ggtatcatcg cccgcaactt gattacaggt aagatcgagc gttacgccgc tcacgctgta
     3481 gttgtagcta cgggtggtta cgttaatacg ttcttcttgt caaccaacgc tatggcatct
     3541 aacggttccg ccgcatggca atgctacaag aaaggcgctt acttcgctaa tccttgtatg
     3601 gttcagatcc acccgacttg cgttccggta cacggtgatt atcagtctaa attgactttg
     3661 atgtccgagt ctttgcgtaa tgatggtcgt atctgggttc cgaagaaact ggaagacgct
     3721 aaggctttac aggcaggaac aaagaaaggt aaagatatac ctgaggcaga tcgcgattat
     3781 tatttggagc gtcgttatcc ggcattcgga aacttggttc ctcgcgacgt ggcttctcgt
     3841 gccgctaaag agcgttgcga cgctggcttc ggtgttaata acacaggttt ggctgtattc
     3901 ttggacttct ccgacgctat caaccgtctg ggtaaagagg ttgtaaaaca gaaatatggt
     3961 aacttgttcg atatgtacga agaaatcacc aacgacgatc catacgaaac tccgatgatg
     4021 atctacccgg cattgcacta ttcaatgggt ggtctgtggg ttgattatga attgatgact
     4081 tctatcccgg gtctgttcgc tatcggtgag gcaaacttct ccgatcacgg cgcaaaccgt
     4141 ttgggtgctt ccgcattgat gcaaggtttg gccgatggtt acttcgtatt accttataca
     4201 atccagaact acttgtcaga ccagattcag gttccgcgtt tcagcaccga tctgcctgag
     4261 ttcaacgagg cagagaagaa tatccaagcc cgtatcaata aattgatgag tatcaagggc
     4321 aaagagtctg ttgattctat ccacaaacgt ttgggacaca tcatgtggga acacatcggt
     4381 atggctcgta acgcagagag cttgaaagag gctatccaga tgttgaaaga cttgaagaag
     4441 gaattctgga gcaacgtatt cattccgggt aacgcagatg acttgaacgt agagttggag
     4501 aaagcattac gtttggcaga ctttatcgag atcggtacct tgatggcaca tgacgcttta
     4561 gaccgtgctg aatcttgtgg tggtcacttc cgtgaggagc accagactga ggaaggcgag
     4621 gcattacgtc acgatgacaa attcatgtat gtctcttgtt gggaatatca gggtgaggat
     4681 aaagaccctg ttatgctgaa ggaagatttg aactatgaat tcgtagttcc tcagacacgt
     4741 aactataaga agtaatcaat cattgcaaaa attagaatca tggataaaga tataaatatc
     4801 acactcaaag tttggcgtca gaaaggtccg aatgtaaaag gacaattcga aacttaccaa
     4861 cttaaaaaca tcaaccaagg cacttctttc ttggaaatgt tggatatcct gaacgagcaa
     4921 ttaatcagcg aaggtaaaga acctgttgtt tttgaccatg actgtcgtga aggtatctgc
     4981 ggtatgtgtt cattgtatgt aaacggacat ccgcatggac cggcaactgg agctacgact
     5041 tgccagttat acatgcgccg tttcaacgat ggtgagacca tcacgatcga accgtggcgt
     5101 tccgccggtt tcccggtaat ccgcgacttg atggtagacc gttacgctta cgataaaatc
     5161 attcaggctg gtggtttcac atccgtaaat accggtggtg tacccgacgc aaacgcaatt
     5221 cctattccta agccagacgc agagatggca atggatgccg ctgcttgtat cggttgtggc
     5281 gcttgtgccg ccgcttgtaa gaacggttca gctatgttgt tcgtatccgc taaggttagc
     5341 cagttggctt tattacctca aggtaaggta gaggctgccc gccgtgcgaa agcaatggtc
     5401 gctaaaatgg atgaacttgg cttcggtaac tgtacgaaca cacgcgcttg cgagatggag
     5461 tgtccgaaga acatctccgt tagtaacatc gctcgtttga accgtgagtt catttgcgct
     5521 aagctacaag actaatattt gattagtata tcatggaaaa ggcgtctttc tctaaaagaa
     5581 aggcgccttt ttatttttgt tatatattga aaaacataat ttagcactac agatcttgac
     5641 aggaattgaa aagtccgtat atttgtatcg tggttttttc ataatagtat tagatttaag
     5701 gttaacaaag tttggttagg gcttgtcgtg agacaggctt taattgttta tagacctacc
     5761 ttttaaatat ggaccacaaa atactgcaaa tagagattgt ttagcgtcat tttatcgtcg
     5821 atctttgcct ttaaagatca tatagtatat gctaataagt attttatttg gcttcttatg
     5881 ttattttctc cgggtgttga tcaaacacaa ggaaaaaatc atgcgccaga taagacaaat
     5941 ggtaaaacaa aaataaaatg gacaaaaaac gaaccaccag ttctttcagg gcaatgagca
     6001 cggaaagaaa actcgagtcg atcttccttt tcgtaacagg ccgatgcaac gccaaatgcg
     6061 cgatgtgctt ctatgcccaa gaaatggata agaagcaacc cgacctcact ttcgatgaaa
     6121 tcaagaaaat atcagaaacc gccgggcaat tcaaccgatt atggatatcc gggggtgagc
     6181 ctaccctgcg tgaggatcta ccggaaatat tggagttatt ctacaaaaac aaccatatca
     6241 aagatgtgaa catccctacg aacggcttaa aaccagaccg gatcgtcgaa tgggtaaaac
     6301 ggttccgcca gaactgcccg gattgtaata ttaacgtaag cctttccttg gatggtttcg
     6361 gtacgaccca cgatacacag agaggtgtac cgggaaactt ctataaggca ctggaaaccc
     6421 tgcgtaagat acaggagaat ttcggagacg acggcaaggt cctgaaaaat atagcaaccg
     6481 ttatcacgaa atacaatata gaccagatag aagacttcat gacttgggta tacggacgtt
     6541 tccgtacctc cacacatacg attgaggccg ccagaggcat gacccgtgac gatggcgtga
     6601 aaatcctaac cgagtcaacg ctacgcaaaa tacaagatga catatcccct atctattctg
     6661 cttatgcgga tcggatggta gcggatacca ccggcttaag gaaaccgatc acacgcttct
     6721 tctatctcgg ccttatacgt accttatata atgtgcgtgc cagcaacata gatcacccga
     6781 ccccttgggg gatggattgt acggccggag agactacctt ggtaatcgac tacgacggac
     6841 gttttcgtgc ctgcgagcta cgggaaccgc tcggaaatat aaaagaatat ggttgcgata
     6901 taagtaaagt gatgaatagc gaagcgatga aacaggaaat agccgctatc ggacatgggt
     6961 ataaagccaa ctgttggtgt acgcacggct gctggatcac ctcatctgtc attttcaatc
     7021 cacgtaaaat gattcgctcc gtatataaag gataccggga aacgaaacga ttgaatcatc
     7081 ccttagccat caatgagcag aaactacaaa cgatggaagc caaataccat ctggacatcg
     7141 agcgtttgcg tcaactgaat atccggtaaa caagaccctc atagcccata aataaacgta
     7201 gcatgaaaat actattagta accagaggct cacaaggcga cgtccttcct tatttggcca
     7261 tagcggccga attggaaaga cgtggccata aggtgaccat caatctccct caaatattcg
     7321 aggagaccgt taaaccctac ggatttaaat acgtattgca gcagtttgac gatatcggcg
     7381 gcatgatcga tagcgcagcg caaaactcac ataaattccg gccattcctt aaatggatga
     7441 ggaacgtgat cgataaacag ttcgatcaat tgattcccct actaaaagag catgatattt
     7501 tagtatcgac caactcggaa tttgctgtcg caagtatcgc cgagtattgc aagaagccct
     7561 tgatacgtac cgcctacgcc ccgttcttgc cgggtaagaa gattcccccg gccgtattgc
     7621 catttcccaa acccaacccg atcatcaccc ctgccatcct atggaagttg atgaaccgga
     7681 tgaccaattt catggtcaaa gacacgatca acaagaaccg ggctaaatac ggactcgctc
     7741 cgatccgcaa ttttggctat cacgcgggag agcgttcata taattacttg cttttcagcc
     7801 agcacctagg aaacatagat ccggactgga cgttcgaatg gtcgatcgga ggctattgct
     7861 tcaatgacac ttttcaatat gatgagaagg cttacgagga aatgatatca ttcgtcgaca
     7921 gcgctcaaag ccctattatc ttttttaccc tcgggagttg tagttccaag gatggtaacc
     7981 gtttcagcaa agccttggtc gatatttgca agaaacatga ttatcggctc atcatcggtt
     8041 ccggttgggc aaagacagga atcaccttac aagcggataa acatttattc ttaatgaagc
     8101 agccggttcc gcataatttg atattcccgc actgcgacgg cgttatccat catggaggtt
     8161 gcggcacgac ccatagcgta ggaagggcgg gaaagcccca attaatcact ccgttgatta
     8221 tcgatcaacc ctattggtcc tatcgaatcc accaattagg gttagggccg gaaggggtta
     8281 agatagcgaa agcgagcgag caggagatcg aacgcaaggt ttgtgatctg gtcaccaatc
     8341 cgctttataa gaaaaatgcc gctcatatag gcgagatgat ccaaaaagag ggaggtataa
     8401 agaatatatg cgactctatc gaaagatttc aatgaggcat aagttcctat tagattttat
     8461 tacatgttac aaaacacaat ttagcactta aaccattgac aaataacagt aactccgtat
     8521 atttgcatcg tggttttttc ataatagtat tagatttaag gttaacaaag tttggttagg
     8581 gcttgtcgtg agacaggctt taattgtttt ataaggtctg cttcccgcaa agcccttcga
     8641 ttacatcaga ataatccgat gcgtcaataa agttgatatc ttgtctttta agatcttccc
     8701 attaatcggt ttcgccgtat aggcatcaaa tccactatta atgatccgtt gctcatcttg
     8761 ggcgaaagca taagccgtca ccgcaataat aggcacgcta gcagaaacct tacgaatctc
     8821 tgcggtagcc tcgtatccat ccatgaccgg catctttata tccatcaaga tcaactgcgg
     8881 tttgtgctga tgaaatagct ccacagcctc ctttccattc catgcatgaa tcaatttata
     8941 ttcaggcttc aatatagact caaacaggcg ataattactg gaattgtcct cagcgatcaa
     9001 gatcgtaacc tcacttcggg cgatcttctc caaagtaaca ggcttctgct cttcactagg
     9061 aaataattct ttcttcggct gaaaaggcaa tgtaaaccag aacttagagc ctttcccttc
     9121 catagaatca accccgatcg ttcctttcat ctgggtaaca atcatctcac agatgcttaa
     9181 acccagtcct gttccttgag cgaaagtatt cagtttcaca aaacgtccga aaatatcttt
     9241 ccgcttattc tccgggattc cgcagccggt atcctctaca tagaaccaca acgtattatc
     9301 atccttcaac ttatagccaa ataagatcga tcctgcctgc gtaaatttca tggcattgtt
     9361 caacagattg atcatcagtt gagacagacg atttcgatcc gtataaatca cgcaaggctc
     9421 cagataatcc ttaaatgaga tctgtacatc cggattctta ttcttcaaat gagccgattg
     9481 ctccaaatcc ctcaatacag cgttaatatc cacatagtca taagtaaact ccaaggtacc
     9541 cgcctcaatc tttgacaaat ccaagatatc gtttatcaac tgcaacaata gggaattatt
     9601 attctcgata atatcagcga attccttctt atcctcaagg tcatcggtcg aggcaaggat
     9661 attagagaaa cctactatcg catttaacgg tgtacgtatc tcatggctca tatttgctaa
     9721 aaacgctgat ttcaatttat tcgactcttc cgccttatcc ctagccattc gaaggtcatg
     9781 ttccaattgc ttacgctcgg taatagatat cgtagacccg atcaacgctt tcggtttacc
     9841 ggaagcatca tattcggcca ttacctgtat ctcctcccac tcatggcgat cttctcccgg
     9901 aatcaaccgc tccagacaat attcttttcg tactttcttt attttcccat tacacaaatc
     9961 atcgaaagcc ttttccacgc aagccctgaa agacgggtgt atcttgctga aatattcctt
    10021 caacgaaacc tcatgggtat gcacctccgc tgtctctata ttatctcccg gatgtacttt
    10081 cgactcatag ataatcttcc cttcagccag attatatcgc cacggtaaaa gatctgccgc
    10141 ctctaacgcc atagccagct tatgattcat ggctttcaaa tgcgtctgga atttatggat
    10201 atccgtaata tcaataaaaa acgcgtcaac tacattctct tccgaggtag gcatgatgat
    10261 aatcgtatag taaagccctg tcggctcaaa ataatactca taagtgaagg attttccact
    10321 ctctaaaacc gtaggcactg ccgataggag caaaggataa ctcccgccaa tcaaatttgc
    10381 gatctctttt ccacgcttat ttaccacaaa atctttagga gcgattttct cctcgaaagc
    10441 atggttcaca tctaaaacct gcacatcgat ttgcgtacct tcccgaatca gtcgctgccg
    10501 tatataaggt aatggcatat tattaaataa atcacggtaa cgggacaata acctcaactc
    10561 tacttccttc atcttttgct tagaacgata cacgtaatgc cacgctaaaa acactactac
    10621 cagaaagaat atcagaaagc ctaacagttg catccaatat ttttccaaga aagagggagg
    10681 tgcattcaag tagatcgcat cacgcgggaa attatcttca ttagatatcg cacttatcaa
    10741 cgaagcataa ttcaaatatt tatgaggatc atttaccgtc gaaaccggaa tcttgcccat
    10801 atcttcaccg ttataaactt gttgtagcaa ggggattaga gcagtctcaa tcgttttagc
    10861 gctattataa tatccaccaa tcgtatatcc ttcttccacg cccatatcat ataaagaaaa
    10921 aacaggatgc ctagaaatgc cgtttatacc ttgatacaaa gtactatata ataacgagtg
    10981 attcaagaaa ggtttctcgg taatccacga gtaatacatc acggctgtcg ctcgatgcgg
    11041 atctttctcc gacagaaccg ccaataaact atccatggag caagaaccct ccgtataaaa
    11101 atccactttc ccctcaggga aagaagtttc catatgtttc tccatctcat cccgaagcca
    11161 tgtggaaaca taacgtctgt cggatatgaa aatcagacgt ctcaaacccg ggattaattc
    11221 cttaaccaag tcgatcgaac ctttaacata ataagggata accaatcccg tagcgttata
    11281 ccccttaacc gcctcttgta aaggaatcac cctatcagag gaatgcctct gattaaaata
    11341 gcattcatct tctgccattt cacccgtttc cgaacagacc agagtgggaa tatcccccca
    11401 tttctcccgg atcttatccc gcataaaagc ccatccattt acgcctaagt agataattcc
    11461 atccggcttc ttcttattaa cttcaaagaa ggcctcttgc ttctctttta atttctctgg
    11521 cgtatcaacc aacatcacgc tcatatgatc tatccggagg gtgtactcct ccggggtagc
    11581 gaacttcgag atcatgttta ataaattgcc agaccagcgt tcgccatcca catatgaatt
    11641 tattaccaat acatacgatt catccttgac cggatatgaa aaactcccat aagccggagt
    11701 cggcataccg gctatcaagc ataaaatcaa tccaaaataa agtattattg cctttaaatt
    11761 tataatattt cgtatcattc cctacattcc tctattgcag ttgtaaagac aaagatattc
    11821 cttaattatc aactaatctt atcaaactcg tttttttatc aagttttggt gtcaaattca
    11881 cgtttcttac aaactaaagg cttttttaat cgggattatt cggttattta ccgatactcg
    11941 tatagaaatc agcggtattt acttgtgtat agaatgacga acccgtacat ttgataaaaa
    12001 acaaaaaaat ggaacttatg gatatgaaag attatgacat cgattttaaa gagaagagga
    12061 caaacgggta tctgatcgct accttattta tcattgtcgg tatattattt ttactgcgga
    12121 atctaggaat gatagatcca tctttatttg acttgcttgt atcttggccg atgctgcttg
    12181 tcgtgtcggg catctttatg attttccacc gtaatccggt aggaggtatg ctcctcgtgg
    12241 gcgtgggagt ctatttcctt ttcccgcagt taaattggat cacgaacgat ttcttacgta
    12301 tatattggcc gttaggatta atcctgttag gattggtcat catgctgaag cggaaagatt
    12361 ctatccgcac gaaaaagcat aaacgtcctt ttaaccatcc ccctttcggg cacagaaagc
    12421 ctaacgatga gatcaactac gagacagata acggtttcgt atcggttgac accactttca
    12481 actcggtaag gcacatcgta ctggaccccg tattcaaggg ggcggacata gacgtatctt
    12541 tcggcaacgt gatcctcgat cttaaaaaaa caacattaga ggctgatgaa accatcataa
    12601 acatagatag ctccttcagc ggcgtagtaa tatacgttcc taaaggatgg ctggttcgtc
    12661 taaaggttga ttccttcttg gctggatgcc aagacatgag ggacctgaca gaaacaaccg
    12721 acatgacgca cacgttatat atatgtggag acttgtcgtt cagcggcctt gaactaagag
    12781 actaaactca tcatgcaaga acatcctatt acaacatcca tattacataa agggcaggga
    12841 agcctattat tacttttagc catagcgatc caatgcgcat tattaactct ttatggcgat
    12901 cttccgttga gcatcacttt ggtcgatagc ttactttcca tcgcattgtt cgccgtagcg
    12961 ggatattatc tttggtatgt acaatgtacg ttacatatca tgcaagcacg agtggctttc
    13021 gccgtactcg tacaaatcgc ttgcatagcc ggatgctcga tcttgctaca aatattcgga
    13081 ttggaagatt gggaggaatt ctcgatcacg attccttttc gattcctgtt cggcctaatg
    13141 gcatggatca ttctatccca atggtatgcc agccgggaaa gaaagagtga ggcggaacct
    13201 atcgggagac aaatggagga aaagacggca cctcccccga ctaccgttcc ggaggagatt
    13261 ctagatcgta tatccgtaaa agacgggaca cgtattcata tcatcccgat aaaagagata
    13321 ttctatttgc aagcatgtgg cgactatgtg accttattca ccacttccgg tcagcacgta
    13381 aaggagcaaa ccatgaagta tttcgagcga agccttcctt ctccggagtt cgttcgtata
    13441 catcgctctt atatcgttaa tacggaacag atattgcgag tagaactatt cggaaaagaa
    13501 acctatcaag tacgattaaa ggatggaacc tatcttcgtg ccagtagcgc tggctataag
    13561 ctactcaaag aacgtctttc cctttagcag tcctataaaa gggacctaat catcgttaaa
    13621 attagaagat tttgattgta atatatagag ttttgtgttg tgtaacactt tttggcaagc
    13681 atcgatatgt tacttaacat atattagttg caaaagactt gacaaatggt cttgacgaac
    13741 gtatctttgc atcgtggttt tttcataata gtattagatt taaggttaac aaagtttggt
    13801 tagggcttgt cgtgagacag gctttaattg tttataggga tttgcttccc tagatttaca
    13861 tataactata aaaaaacggc cacccctaaa aagaggcgac cgtaattatt cttaatgaaa
    13921 gaacctactc tttgacaatc cttgtaactt ccaaatcaaa gatcaaagtc gtataaggct
    13981 ttattatgac acttcccgaa gcactccttc cagccgaacc gtatcccatc tgttgaggaa
    14041 tccaaatctc ccaacgatct cctgggtgca tattctgtaa cgctgtagca aaaccatcta
    14101 ccatatcaga aacagtaagc tcggcaggct ctccagcctc gaaagaacga tcatcaaaaa
    14161 cttcaccatt tataaaagag cctttataat aacattccac cttgctcgta taataaatcg
    14221 gctccttact ctccccagtc ttcaagacct tgtaaaggat aaatccggca ttactttgag
    14281 aactcaattg ctcgaaaccc ggaaccagca tctgggcttg aaaagcctcc tcattctgga
    14341 ccttccaaac ctcatccacc tctagtgcct catcatcatc cccacaagag gtgatcatga
    14401 gcacgcaaaa caacatcaac gcgatatgcc agtacttctt cattcgttta ctctattacc
    14461 tttttcaata aattcttcat actcaccttc tccgtgataa tatcgtgaag cttatcgatg
    14521 cttacgcgct cttgctccat cgtgtcacgg aaacggatcg ttacgcaatt atccttcaag
    14581 gtgtcatggt ctaccgtaat acaatacggg gtaccgatcg catcctgacg gcgataacgc
    14641 ttaccaatag aatccttctc gtcgtattgg caacggaagt cgaaacgcaa catatttata
    14701 atctcctcag ctttctcggg caggccatct ttcttcacca atggcaatac ggccaatttg
    14761 atcggagcca aggctgcggg caacttcaat accacacggc tctcgccatt cgccaacgtc
    14821 tcctcgcagt aagaacccgc catgatgctc aagaacacac ggtctacacc gatcgaggtc
    14881 tcgattacat acggagtgta actctggttc aactccggat cgaaatattg gatcttttta
    14941 ccggaaaact tctcatgctg actcaagtcg aagttcgtac ggctatgtat accctccact
    15001 tccttaaatc cgaacggcat ctcgaactcg atatccgtag ccgcgttagc gtagtgagcc
    15061 aacttctcat gatcgtgata acgatacttc tgatctccca agccaagagc ttgatgccat
    15121 ttcaagcgag tagacttcca tttcttgaac cactcgatct cctcacccgg acgaacaaag
    15181 aattgcatct ccatttgctc gaactcacgc atacggaaga taaactgacg agccacgatc
    15241 tcattacgga acgccttacc gatctgggcg ataccgaacg ggatcttcat acggccagtc
    15301 ttctgcacat tcaagaagtt cacgaaaata ccttgggccg tctccggacg aagataaacc
    15361 ttcatcgctc catcagcggt agaacccata tccgtagaga acatcaagtt aaactggcga
    15421 acctccgtcc agttacgagt tccggaaatc gggcaaacga tctcgcaatc caagatcaat
    15481 tggcgaagat cctcgaagtt agactcgttc atcgccttgc tataacgctc atgga
//
