LOCUS       c00016_gnlPro..        13765 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EANCLMDJ_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:59:41
            Original ID  :: gnl|Prokka|EANCLMDJ_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13765
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13765
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[275:3765]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      276..3765
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13765
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13765
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(276..1043)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1084..3042)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3064..3765)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3966..4238
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4241..5056
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5090..5497)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLDLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5752..6459)
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLTESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6754..7494
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(7712..7846)
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGRYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(7958..8158)
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8172..9377)
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATKDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9401..10147)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_12"
                     /sec_met_domain="adh_short_C2 (E-value: 2.1e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10276..10794)
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10858..12468)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12591..13298
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ctaattcctg taatcaacat ttttctttct ctcgaagaaa gatgggggcc gtcgctgtcg
       61 gacgggggct tgcttaggtt tcgtccggca tttccaagta cggtctcctg gattactggg
      121 tgccttccgg tgtaacaatt ttttacgctg cgcgacgatg aggaagcaac tgtctggtat
      181 tttattcctg gttcaaggaa atctggtaat gaaaaaactc ccgacagccg atgccgccgg
      241 gagtttttac agagcgtctt aagaaggaat cttctttaga aacagaggcc ttccttggcg
      301 ttggcccgca tgaagtcgcg gttgaggcgg gcgatgttgt ccacgctgat gcctttcggg
      361 caggcggctt cacattcata ctggttcgtg cagttgccaa agccttccgc ttccatctgc
      421 ttcatcatgg ccaggacgcg cttggaacgt tccggctggc cctgcggcag cagattgaga
      481 tgggcgatct tggcggaggt gaacagcatg gcggaagcgt ttttacagga ggccacgcag
      541 gcgccgcagc cgatgcaggc ggccgcgtca aaggcggcgt ccgccttcac tttttccacg
      601 gcgatgttgt tggcgttcgg cgcggaaccg gtacgcacgt caatatagcc tccagcggcg
      661 atgatgcggt ccagggcgga gcggtccacc atcaggtccc gcaggattgg gaaagccttc
      721 gcgcggaagg gttcaatcca gacggtatcg ccatccttga acttgcgcat gtgaagctgg
      781 caagtggtca cctggcgttc cggcccgtgg ggaatgccgt tgatggtcag ggagcacatg
      841 ccgcagatgc cttcccggca gtcgtggtca aaatggatgg gttccttgcc ttccttgacc
      901 aggccttcat tgacgatgtc cagcatttcc aggaaggagg cgtccaccgg aatgtccttg
      961 gcggcatagg tctcaatgcg gcccttggct tcccggtttt cctggcgcca gaccttgaga
     1021 gtgagattga gtgttttagc catgttataa tctttctttt gagtgttaat gtattggcta
     1081 tctttacttg tagctgcgga tggcaaggtg cacgttctcg aaggtcagcg gttccttgtg
     1141 gagaacaggc aggctgtcca cgccagtgta ttcccaggcg gctacatagg cgtattcatc
     1201 gtcgttgcgc ttagcttcgc cgtccggcaa ctggtattcc acgcggaagt gggcgccgca
     1261 ggattcctgg cggttcaggg cgtcatagca gagcagctgg gcgaattcca ggaagtcggc
     1321 cacgcggcag gctttttcca gttccgcgtt gataccgtcc gccgtgccgg ttacgcgcac
     1381 gttttcccag aattccttgc ggagctgggg aatgcgttca atggcgtggg tcaggctttc
     1441 ttccgtgcgg gccatgccgc agtcttccca catgatgagg cccagttccc ggtggaagga
     1501 gtccaccgtc ttggtgccct tcacattcag gagcttgttg atgcgttcct tcacttcgtc
     1561 ttccgcagcc ttgaattccg gggcggcggt ggtgacggcg ccgggcttgg tggtcgtcag
     1621 gtaagcgggc agcgtggcgg gaatgacgaa gtagccgtca gacaggccct gcatcagggc
     1681 ggaggctccc aggcggttgg cgccgtggtc ggagaagttg gcttcaccga ggacgtgcag
     1741 ccccttcacg ttggacatga ggttgtagtc cacccacagg ccgcccatgg tgtagtggga
     1801 ggcggggtag atcatcatgg gcgtttcatg ggggtcgtcg tccgtgattt cttcgtacat
     1861 gtcaaacaga ttaccgtatt ggccgtcaat ccattcgcgg cccatgcgct tgatttcatc
     1921 cgcaaaatcc aggaagacgc ccttgccggt gacggccacg ccgcggccgt cgtcgcaggc
     1981 ttccttggcg gcgcgggagg aaatgtcgcg cggagccagg ttgccgaagg agggatactt
     2041 gcgttccagg tagtagtccc gttcttcttc gggaacatcg gaaggcttga tttccttctt
     2101 acggattttt tctgcggttt cacgggactt gggcacccag atgcggccgc tgttgcggag
     2161 ggattccgac atcagcgtca gtttggactg gtagtcgcct ttgaccggaa tgcaggtggg
     2221 gtggatttgc gtgaagcagg ggttggcgaa gaaggcacca cgcttgtagg ctttgtaggc
     2281 ggcagtgacg ttgcaaccca tcgcgttggt ggacaggaag aacacgttgc cgtagccgcc
     2341 cgtgcagagc aggacggtat cccctgcgta ggatttgatt tcgccggtaa ccagattgcg
     2401 ggtgacgatg cccttggctt cgccgtccac cagcaccaga tccatcattt catggcggga
     2461 gaacatttca atgtgtccct tggccacttc cttttccagg gcctggtagg cacccagcag
     2521 gagctgctgg cccgtctgtc cgcgtgcgta gaaggttcgc ttgagctggg cgccgccgaa
     2581 ggagcggttg tccagcaggc cgccgtattc acggccgaag ggaacgccct gggccacaca
     2641 ctggtcaatg atgttggagg agacttccgc cagacggtag acattggctt cacgggcgcg
     2701 gaagtcgccg cctttaacgg tgtcgtaaaa caggcggtaa acggagtcgc cgtcgttctg
     2761 gtagttcttg gccgcgttaa tgccgccctg ggccgcaatg gagtgggcgc ggcgggggct
     2821 gtcctggtag cagaagcatt tgacgttgta gccaagttcg gcaagcgtgg cggcagcgga
     2881 ggcgccagcc aggccggaac ctaccacaag taccgtgtac ttgcgcttgt tgttcggatt
     2941 gatcagtttg gactcaagtt tgtacttgga ccatttgtcc tgaatagggc cggagggaat
     3001 tttggcatcc ggcatccagt cgcttacggg aaaattaatc atgactttga gaggagttga
     3061 tggttatttg atgataccca gaagaaccga gaccggcacg gagatgaagc ccaggcagat
     3121 aatcgcgccg taggcgatgg cgataaagtt gtagaagggc cggattttgc gggaatcgac
     3181 gcccacagtc tggaagatgg actgtacccc gtggcgcaga tggctgaaca gcatcagaac
     3241 ggccaggatg tagaaggcgg agcaccatac gttggagaat ccggtcacga tcatcttgta
     3301 cacgtcaaag gtttccaccg taccgtcgga aataaaggtg gtgaactggg cggggtcgta
     3361 tcccacgcgc agggtgtact ggtacaggtg gtagatcagg aacaccagga cggtcaaacc
     3421 ggtatagatc atgtagcggg aggagagcgt tgccttaatg gtgttcttga acacgtaggg
     3481 ttcgcgggcc gcatggtttt ccagcttcag ctggatggtc agccagacgt ggatgatgaa
     3541 gatcaccgca agccccgcgc ggattcccca gagggctgct tccggcatgg agtgcaggcc
     3601 gtgggcgtag gtgttgatcc attcagggcc tccgaagatg agaaggttgc ctgccaggtg
     3661 tcccgcaagg aacaagacca aacataaccc cgtcagagcc acaatgattt tgcggccgat
     3721 ggaggatgtc acgaatgtac atatggtttt tactagtgca ttcataggcg ctctaatgaa
     3781 ataaatgcgt cttcacagga tgcccggttc aagcccggat ggcaagcctc ttcttgaatt
     3841 tccggcgctt ttcggatttt tgaaaaaccg gggaaagagg ttgctgttta tcagtttgga
     3901 atggttatca ttttgttgcc tgttccggct tgacgaggct ttccgcatag gcgtatcgtc
     3961 tgtgcatgaa aagaagtaaa aaggaggtgc tggacgcgga tttcgcagcg gcgcgcgccg
     4021 gcgttctgga tgtggccgca tttctggacc gggtggaccg cggggaaggg gaggcggatt
     4081 tccgctacca tgccctgatg gatgttcttc ccctcttgtc cgcatccggc cccggacgcg
     4141 tccgggccat tctggaagcc ctttcctaca gggatgacac cgtgccggaa accgccgcag
     4201 ccaaagcggc ctgcggagcc ccgaacctca gcaaataaga atgatggctt tcatagaacc
     4261 tcatatacat atggtgtgcc gcaccacgga cgaataccgg gccatggcgc aggccggctg
     4321 cctggcggta ggggaaccgg cgttctgggc cggttacgac cgttcgtccg cggacggttt
     4381 ccgggattat ttcgtacagc ttacggaatg cgaacccgcc agggcggcca agttcggcat
     4441 ggaccattac acatggctgt gcatcaatcc caaggaggcg caggacgtgg ctttcgcgcg
     4501 ggatgtgatg aaactgattc cggagttcat tgaccggccc aatgtcctcg gcatcgggga
     4561 aatagggctg aaccggaata cttcccatga aatgactatt tttgaagagc atctggatct
     4621 ggcggtgcgc ctcaaccagc ttgtgctgat tcacactccc catctggaag acaagcttaa
     4681 ggggaccgta atgattcttt ccgccctgaa aaaccgtccg gatctggacc cttgccgcgt
     4741 gctggtggat cactgtgagg aacatacctt cccgctggtg aaggaggccg gttactgggc
     4801 cgggctgacc ctttatccca ccagcaagct gaatcccaag cgggcggcgg atattctgga
     4861 attgtacgga atggaccgtg tctgggccaa ttccgcggcg gactgggggg attccgatcc
     4921 cctggcgctg acggccctgg cctgcgagct acgcaggcgc ggtttttccc ggcaggaaac
     4981 ggaacgtctt ctcctggaaa atccggagac attcatggga cagtccccga agttccggaa
     5041 agtgtcgtcc cgctaattcc gcccgaggcg cggcggagga tacggccctc tagtccccgt
     5101 ccgggaaaaa gacggtgagg acggcgccca ggatgaccgc cgcgtcatcc agaaggtcca
     5161 gcctgccgat tccgtcaaac aggaattcgt cgggagtcag gatgtaggcg ccggcggcgg
     5221 ccagaaggca tatattccgt ttgttgaaaa aacgcggttc tccttttctg cttttgaaat
     5281 accggaacag gcgcagtagc agctgctgtt tttgaaggtt catggacggg aacgggggat
     5341 aaaggttcaa gctcagccat tttcccactc cttttccctg tttcggggaa ggagtctgtt
     5401 gccgacggac ggaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg
     5461 ggctgttccg gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc
     5521 atgggaaaaa ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgacccta
     5581 ccgggggaga ctgaatgcca tttttccgtc aagtgctggc cgtgaggttg ccgcagcaaa
     5641 tggaagcttt tcccctctgt tttttcggca gatgtttgaa cggataagga aaaggccggc
     5701 tcacgatttt gtgagccggc ctttgaatat agggaggcgg acggtacagg cttatgccct
     5761 gcggcggcgc atcatcagcg cggccagtcc cagcaggccc agggaagccg tggcgggttc
     5821 cggaatgctg gcgatttcac tcatcagttg accaacttgt tcctgggaaa ggagggagtc
     5881 gtggatgtag agctgttcga tggattcagt cagtcctgcg tccatgagaa tctgatcaat
     5941 ttgctggttg ccgaatttca ggccgctgtt ggaatagtac gtagcgctgt cgccaaaata
     6001 gatgcgggtg ccaagatctc cggtgactac ggaaatggtc agggaccctt ccgtgcccag
     6061 cggggtgtca acgacgggcc cgctgtatga ggtgttgttc cataatccct ggagtttccg
     6121 gtccgtgttc aggcccacgc cccagcttac actgctgttt ttggcgttaa acagagcggt
     6181 ataggtctcc ggagtgttga ttttggacag atcaagaacc atcgtcacag acataacgtc
     6241 gcggttgttg gtaccgtatc cgttgaaggt tatcccggat aacgtcagat tgctgtcgtc
     6301 agacgtgatg gaaacggaat ctttcagggt gccgaaatcc gccgtttggg aggtaaagtc
     6361 cgaatatccc acgatagagc tatccagcag agtggtattc gcggtggcgc tcaggctcat
     6421 gccggccgaa agaatcaggg tggataataa tttcttcatg gtcagtatct taataaaatg
     6481 atgcaagatt caatgtatgc acttgcgctt gaataacgaa tttggaattc cccaatcgga
     6541 tttggaatcc gtcaagtaat gaaaaagagg ccaaatcaat catgaaacca atgaataaca
     6601 aagattgccc cgtcatcttg acaaaagaac cagagatatt aaaaaatcat tattttcaat
     6661 gaattataaa tacaatatac taacccttaa tatttttaat tgcttgcgga ttccaaattc
     6721 gctacaagtt gccatccaaa aggaataata aatatgaaga aaacactgac atttttaatc
     6781 gcgatgggaa gctttgctgt ttcctcggag gcagcgaccg tttttaatta ttacactccc
     6841 ggtacggata attacaatag taccatccat gggttttatc ttggcctggg gtcttcttcc
     6901 ctggctcctt ccgattcctc ttctccctcc tccctgtccg gagagatcag actggacagt
     6961 tttacgctgc gcggagccgc caacaatttg ggcgctaatg tcacttacgg cttcctggtg
     7021 ctgaatggct ccgacaattc ggtcatcggc tggagcacca atacgggaac tactgcagca
     7081 gggattaatc tgacgttcag tttttcttcc ctggatggtt ctcccctgct tcttgacgcg
     7141 gcattgacat accgtttcct ggccgtgagc cagtccgtga tggacttgat gcaggatacg
     7201 tctaaaacgt atttatatgc tgcgggggga acagccgccc ctactgctaa cacggaagga
     7261 gataccgtaa cgatcagcgg cggattgact gctcccggca tccgcggcca ttatgacgcc
     7321 gagggagcgc ctggtgattc tgtcgttatt acgggagcca acggaaccaa tactttcagc
     7381 ttattatccc cgattttcac ggaaatccga ggggaaatgg tgccggaacc agccacggtt
     7441 tccctgggcc tgctgggact ggccgcgctg atgatgcgcc gccgcagggc ttgagcttcc
     7501 tgatggcgaa aaatcggcgg atgagagctg ttcttgcgga acagctcttg ttttttatat
     7561 ccagagagga agaattgctt atccgtatgc gggattcatg ccctccggaa ggtacggaat
     7621 ttccgggggc aggaggccgt atccggtttt ttcggcatgg cggcaatttg ctggaaacgt
     7681 ttttgagacg cagtaccgga aagctttttc tttaccggaa aatgccgtca aattcggcag
     7741 cgcgcttttc gtccatatgg tacacggcag ctttcacata gcggcctttc aggccggata
     7801 gggaacccct ttgcagctca cagacctgga gggccgccgc atacatatta ttcgccgtcc
     7861 tattccccgg cgctggtatt tcggaagaac ggcaatgggc cccatgccca gcacttcata
     7921 ttcttttcca tcgtctgccc tgatgacgga cgttgcatca acgatgtttc ccgacgatgc
     7981 ggctgccgtg gacggcgact gcatccagct ccgggatgaa ggacggactg acgcgcatga
     8041 tatggagcag gtaatgttca tggcagccgg ggacgaaata gttccagaac gcttctctcg
     8101 tgacatgttc cgtttcggca tggtctgagg attgttccgt tcttaatgca atggtcatga
     8161 aaggttgttc tttacggctc ccccttggag aaattccaga ggcggtgcat cgtcataatg
     8221 tccggaatgt tcatggggcg caccacgcgg aacccgatca tgcctccgtc cgtcaggtac
     8281 cagatgcttt tagggttttg aggatcctga cggttccagg cgggggtgct ggcgcggcgc
     8341 gcagcgcttc tcaggctgtc cgggtcgtct tcccacgaac cgccgcgaac gatgtgaggg
     8401 gcgccgggga tgatgaccaa ggggtctttc gcgggcaagc cgctccgttt gccgtaggca
     8461 tccggaacgt aagagtccaa aacccattcc gccacatttc cgtgcatgtc ccggagtccc
     8521 cacttatttg gttttttaga gcctgttttc tggtagcggt cattggagtt gttccagtac
     8581 caggcgtact ggtccagaga ggcttccccg tttccgtaag aataggcgcc gggggagccg
     8641 gcccggcagg cgtattccca ttccgcctcc gtgggcaggc ggtagtaatg cccggtctgg
     8701 gcgctcagcc attcgcagaa tttgctggcg gcgtggtggg acatggagat ggcgggcaga
     8761 ccgtgttcat agccgtggcc catgcccagg ttcatggcgg tgtagggggc ggtaggctgc
     8821 gtaacggagt cccacagttc gtcatccggc tgttcctcca gaagctggcc gtccttggcg
     8881 cgcggacgcc cgttttccat gaaggccgta taaagttccc aggggatttc cgtttccgag
     8941 atccagaagg gggagatgct cactttatgc tgcggacctt cgtccggttt ccggtgcggc
     9001 tcttccgcgg gactccccat gaggaacgtt cctcccggta tggcgaccat gcgcagggaa
     9061 gctcccgcca cgggaaccgt ttccgtgtag gattcaaaac gtgccggatt tccggaagct
     9121 tcaatgagct gatggatttg gcgcgttgtg ccgaccagct cccgggacgg caggtcatcc
     9181 ggaatgggaa gggcaggacc ggcagcgcgg tccagttccc gtttttgcag cgcggatcgg
     9241 ctttctcccc actggcgtgc gctggtaatg cgcgcggcat ctttcgtggc cgggcggggg
     9301 gaattatttt cttcccggca cccggccagc agggcgcttc ctcccagaaa gcaggaaaca
     9361 aggaaaatgc cgcgcatgga atggagaaaa ccggaatgcc ctacatcgtc atgcctccgt
     9421 cgcaggcaat gacctgcccg gtgatgtaac gggcatcgtc agaggcaagg aaggccgtca
     9481 gggcggcgat atcttccacg gaaccttgtt ctttcaaagg tattttctta acgatttctt
     9541 ccttgagatt gtcgggaatg gcattggaca tttccgtgga gatgaagccg ggagcaatgg
     9601 cgttgcacgt gactttgcgc ggagcgaatt cctgagccag tgatttggtg aaaccgatga
     9661 ggcccgcctt ggaagcggcg taattggcct gaccgatgtt gccgacgaga ccgatgacgg
     9721 agctcatgtt gatgatgcgc ccggccgggg atttcatgag aacacgctgg agggccttga
     9781 ccgtattgaa cgcgcttttc aggttggtgt ccagaacggc atcccagtct tcctctttca
     9841 tgcggagcat cagggagtcc cgcgtgatgc cggcgttgtt caccaggatg tcaatctgcg
     9901 ggaagtcttt caaaatggcg gccatggttt cctgaacggc cgcgtaatcc gctacgtcgc
     9961 aggggtaggc cttgcaggaa tccggaaatt ccttgttgat ttcttctgcg gcccccccgc
    10021 agctggatgg actgcggctg atcaggatga ccctggctcc ttccgaagcg aagcggcgcg
    10081 cgacggcatt gccgattccg cggcccgcgc cggtaacgat ggctgtttta cctgctaact
    10141 tttgcatgct gcccacagta aacccgtttt tcacggttcc ggcaagcttg aaatggactt
    10201 ggccgcgcag gaacccatac ggggaagggg cgtgccggga atgaaaaaag agggggggag
    10261 aaacggggcg gggggctact gtccggcctc ttcattttcc cggagtgcac cggggggcgc
    10321 cccgtcttca tccggttcta ccaggtcgct gaattcatcc gaattttcca aaatgtcctt
    10381 taaggcggcg gaaccgtaat agcgggcctc aaacaggcgt ttgccttcct gcctgcagcg
    10441 gttgtccagc atttccattc gtttttccat tttttctatc aaggcgtctt ctttctcctt
    10501 ttccgcatcg ttcaatttat cctgaagctg gaggaaatgc cggatgtcct tctgaatgtc
    10561 ctgcagcgtt ttgacggcgt tgtccgcgct ttccttgtcc tgaacgcctg ccaacgtctg
    10621 ctggatattg atggcaaagg aaaaggcctg gttgatcagg gattccgcgg aaggaatttt
    10681 ttccgccgga gccgctgctg cgggggaagc cgttccggcg gccgtttcac caaatgcaag
    10741 agaggctccg gacagaagcg cagaatataa gagaggaaca agaaaagcct tcatcctgtt
    10801 cttttaaggc aggatgaaat ccacggcaag gaaaaagggg aaactgaaaa aagagcctta
    10861 ttccgccgtg atgccgcctt tttcatcgtc cagaatgcct gacttttcca gatagtagtc
    10921 atatccacct gcgtaggcgg tgatggtccc ccggttcaca tgcagggttt tttgtgccag
    10981 ggaacggatg aagtgcacat cgtgggagat gaagaccagt gttccttcat aatgcttcag
    11041 agcctgcacc agggcttcta cggacaaaag gtccaggtgg gtggtcggct cgtccatcag
    11101 caggaggttg ggcggatcca ccaggaattt gaccaggctg agccgcgatt tttccccgcc
    11161 ggaaagaacg ctgacgcgtt tttccacatc cagcctccgg aacaggaagg aacccaggat
    11221 ggaacgcgct tcttcctccc ggatttcagc gctgcatttc atgatttcct ccagcacggt
    11281 attttccgga ttcaggtttt ccgttcgcgc ctgggagaag tagccgatgc gcgtcgtggt
    11341 accgggagtg cgttgtccgg agtcaatggg gatgatgccc gccaggattt tgagaagagt
    11401 ggatttgccc gcgccgttcg ggcctacaag aacagtgcgc tccccgcgtt ccaccagcag
    11461 gtccaggttt tcataaaccc tgcggtcgcc ataggattgg cagacttttt ccagctcaat
    11521 gactttctgg gtgctgcgcg gaggctgggg gaagttgaat ttaaatactt tcctgcgggc
    11581 taccggtttt tgaatgattt tcatcttttc cagctgcttg atgcggctct ggacttgccc
    11641 ggctttggaa ttgatggagc ggaaacggtc aataaattcc tgaatgtgcg ctatttcctt
    11701 ctgctggttg cggtaggccg cctgaagctg ctcgaagcgc acgtcctttt gttggaggaa
    11761 gtccgagtaa ttgccgcggt attccaccag ttcttcgttg tcgatgtcgt acacgctttc
    11821 caccagctca tccatgaaat cccggtcgtg ggaaatcatc aggatggctc cggggtagtt
    11881 tttcaggtat cgctggagcc acagcaggga caggaggtcc aggtggttgg taggttcgtc
    11941 cagcatcagg aggtccggct ccaggacaag gagcttggcc aggtacgcgc gcatgatcca
    12001 gccgccggac atttcccggg cggggcgatg gaagtcgctt tcccgaaagg ccagcccttt
    12061 gagaattttc ttggctttgg gctccagctg gtaaccgttg gcggcgttga aagtgtcaat
    12121 ggcttccgcg tattccggcg tatccgtttt gttggcgttt tccgccgtcc ggatggtgtg
    12181 gatggcctgt tccatttccg gcgtgatgcc cagggcgatt tccagaacgg tttcatcctt
    12241 cggttcgctg gcttcctggg gaagatagcc cacgatggcg tattcatcca tgctgatgga
    12301 gccttcgtcc ggcgtgtctt ctcccagaat catgcggaac agggtggatt tgcctgctcc
    12361 gttggggcca accagagcca cccgttcccc ccagttaatg gtcatttccg tttccctgaa
    12421 caaggtccgt ccggcgtggg attttgtgag atttttgatc gtcagcatgg tgaagagagg
    12481 atgtattcta ccgggatgga aaggggaagg caagagccgt cagggcggag gcaggcattt
    12541 ttgaaagctt tactggattt ttacgcgtag tctgctagcc ttggcgcgcc atgccgacca
    12601 cgcagacatt caggcttttg cttgctgccg cccttttgtg cggatggagt tcctgctgta
    12661 ctcctccggc ggaggattat atacaacaaa cttacgtgca gcagcaaatg tccgggctgg
    12721 ctaatgcctt cctggcgctg ctgccgccgg atcaggcctc tcttcccgct gccggagcgg
    12781 aggccaggtg gctggcggac acggccgtgg tccagtccgc cgcgattgcc cgggacaaca
    12841 ggactgtgct gtttggctgg ctgaacaata ttctggtcaa ttccaacctg cgcgacaggg
    12901 ggttgtgctg gcaggtccag caggatttgt accgggacct gcgccgccgc cccgtgaagt
    12961 atttccgcat agggctgacg attcgagacc gaggaacggg cagggagcac agttgcgtgt
    13021 atgtcaatgc cgcggggaag ggattgcagg gctccattgt tctggatgcc tggaagaact
    13081 gcgggcatct ggtgacgctg acccagaagg accgggaagg cggcaaatgg gaggaggact
    13141 ggcgggaacc atttgtttcc aaggcctttc cggagggcca ttcctacggc atggaacatc
    13201 acctggtctg gcccgggtgg gccaggaaac gccccattct ggttcagcgg atattccagt
    13261 ccgatcagca gaatgaggcg aaggcggccg ctgaataaag gggaagcctg atccggcagg
    13321 aaccggcaca cggtgctgcg ccgcggcggt ttgcggtatc ctccgttttt aaggaaaatc
    13381 ccggcgaatc ggcaaatggc ggagggaatc cggactcagg gcaaataaaa acgcactcag
    13441 tgcgtacacc gagtgcggat taattggata atttgctagt gttgcagggc aaaaccccgc
    13501 tgcaaactta cttgcccttg gcctgcacaa ccggagcggg agcaggagcg gtggtttgct
    13561 gttgctgctg ctgctgggag caggaagcga ccaggcaagc ggcgccggcg atggcgagga
    13621 tagcgatgtt cttcataatt cgaattaaat acagtgtttg ttaactactg gaacctccgc
    13681 atccacggag gtttgctggc accaatgtaa atggtggcaa gtagaaatca agagattttc
    13741 ttgttccatg tcacggcatt acaga
//
