LOCUS       gnlProkkaNOPPFHOF_6    12540 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOPPFHOF_6.
ACCESSION   gnlProkkaNOPPFHOF_6
VERSION     gnlProkkaNOPPFHOF_6
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 21:08:24
            Original ID  :: gnl|Prokka|NOPPFHOF_6
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67860
            Orig. end    :: 80400
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12540
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11557]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12540
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12540
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             845..2176
                     /locus_tag="ctg6_56"
                     /transl_table=11
                     /translation="MEENQHTEFKESWHDEYTRYISAFCNTEGGVLYIGIDDKGEVVGI
                     EQPKKLIEKLPNFIAQKTGIMPLIHLREKAGKEYLEIEVQPSAMPISVHGRYYTRSGSV
                     TSELQGNQLNMFLAAKMGLTWESVIEEDFSLEDIDTDTVERFKLLAKDRVPSIEQETDL
                     LALMERLNLIVGGRFKRAAVVLFGKNVQRYVLQARIKIGKFLTDTEVLTTDIVEGNLIQ
                     QVDRALDILRTKYLLSYISYEGIHRREKLVYPYEALREALLNSIIHREYFVSSEIQVRV
                     YEDKLVIGNEARLHDITVEDLSRPHPSRPHNKLIADVFYKAGFIESWGRGTQRIIDNCL
                     AEGLSAPVYEHKMGFLYLTFFHERINERINERINERINELSDMEREVYQILREEPTIRQ
                     IDLANRLDLTEQYIRKLIKKLKEHGWIERIGARKNGYWKIIEKS"
     CDS             2173..3435
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 121.7;
                     E-value: 6.9e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_57"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-25,
                     bitscore: 82.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILILNTSELTGGAAVAANRLAKALGKSGVEVSMLVRDRKTDHV
                     KVFSVNNSWTSHRLNSFRFIWERLIIFICNFFSKKNLFQVSIANTGTDLSKHPLVQQAD
                     VIHLHWVNQGFLSLSDIKKLVNTGKPIVWTMHDLWPATAICHYPGGCEKYISNCYQCPM
                     LKRNPFFDLAASVFKEKGKIGLSKITFVGCSRWIMEEAQKGNWLRTACFTSIPNPIDVT
                     AFKRMEKRVARKRFDLPEGKFLLLFAAAKLSDTRKGAIFLIEACEKLKEKYQDRIEIVL
                     MGNSSEELISQFPFKVNTLGYISDQDSMISVYACADMFVIPSLEDNLPNTIMESMACGT
                     PCVGFETGGIPEMIDHLKNGYVAKYKDTNDLAVGIKWIIDNQETFRFSEACVRKVHDCY
                     RESVIAEKYIALYQSLCNKRK"
     CDS             3534..5396
                     /locus_tag="ctg6_58"
                     /transl_table=11
                     /translation="MDDQHKPEWIKVDEWDFVEYVDSLLRSQEAVDLEFKTARAGFPNS
                     VWETYSSFANTDGGTIVLGIKEKNGALFVEGLLPEQIVSYRQIICNQLNNPDCVNVNLL
                     TDKNIQEVDYRGKSLLLIYVPRASRSQRPVYLTRNPLNGHTYKRNNEGDYKCTDTEVRR
                     MIADADEEHPRDSRILCNYSMEDIDLDSLKQYRLLLSSRQPDHPWLTLDDMAFLRKLGG
                     YRQDRQTGQEGFTLAGILMFGRTESITDNECAPSYFPDYQEKMSVDENVRWTDRICMDG
                     TWEANLFQFYRRVYPKLSSVLPKPFRLENGVRLEDTTTHVALREAFVNTLVHCDYMEEG
                     NITIEQWKDRYVFKNPGTLLVSKAQYYAGGESICRNKSLQKMFMLIGFSEKAGSGVNKI
                     FMGWKNANWRPPFVEEQSHPDRVVLNLPMESLYPEEVLEELKRLFGREIERIPYDQFTV
                     LALCYSEKQVSNERLQYILNQHSSNITKLLKSMCNAGFLESIGNGRGTRYRLLFLEKDE
                     SKPQKDESKLKKDESKSQKDESKLEKDESKKYMRYEDLSRLILSVCEDYVALEIIAEAV
                     HREASYLINRVIPRMLEDGLLERLYPSSPKHPLQKYRVRQVGNL"
     CDS             5403..6170
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_59"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.1e-30,
                     bitscore: 97.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMNQQPTFSIITITYNAERWLERTILSVLSQSYPNIEYILIDGA
                     SKDKTVEIIKQYESGIASWISEPDKGLYDAMNKGLKRATGDYVWFLNAGDTLYTADTVQ
                     RIVASLKKKVSLPDVIYGETQIVDAEGRSLGMRRLKAPEKLTWKSFRMGMLVCHQSFIS
                     KREIAPLYNTEYRLTADYDWCIQCLRRSKRIHNTRLTLSNFLEEGLSSVNRKASLKERY
                     EVMCKYYGKVSTILLHGWFAVRFYFAKWFKGRV"
     CDS             6194..8698
                     /locus_tag="ctg6_60"
                     /transl_table=11
                     /translation="MRSIMSKWGKHIAAIAVFLVLTVIYFSPAVFEGKVVRQGDTEKAI
                     GMGNSQMDEYEKTAQPGEFSAWSDAMFGGMPYVSGYGNPAPRFPGYLLVEKPLKALGYM
                     DAGMVFTGFVCFYILMCVMGVNWWLAIAGAIAFALASYNLIIIEAGHVTKAYVIAYMPL
                     TLAGMALLFKRKYLWGAVVFLLGVAFSIANTHLQITYYLLLLCFFVYLGYLFNKLKEKA
                     YKELGTVTAIMAGCVILAVLPNAQNMYAQWDLGQNSIRGATELTTTTPSGEKISSGLDK
                     DYAFAWSYGKGELLTLLVPNAYGGSSGGMLGPDSELYKELRAKGAQVGKEVQAPTYWGE
                     KTFTSGPVYFGALVCFLFVLGMFVIRNPMKWWLFGGSVFLILLALGRNFDSFNDFMFHY
                     LPMYNKFRTVEMALVIPGMVFPIIAIWGLKEVLSETVSDALLKKGLIAALAITGGISLI
                     LWLMPSMLLDFRSSFDAQYQLPDWYYNALLMDRASLASADALRSLVFILLGAALLFWFY
                     TSKDRKKVATFVGIGVAVLMLVDLWTVDKRYLNDSNFIRQKPTEVYKETVADQEIMKDK
                     DLSYRVLNLNNPFLETTTSYYHHSVGGYYAAKLRRYQELIDHRLQGELNSVIEAFQKAQ
                     IAEDLMGAFAACPSLNMLNTRYIIYNPEQPPLRNPFAFGNAWFVDKVEVVENADAEIAA
                     LNTINPLTTAVVDKRFADEVKGFTPQLDSTATITLDSYRPNKLVYTTKTNSEQLAVFSE
                     IYYQPGWEATIDGKPAPHFRADWILRAMLVPAGEHQIVFEFRPQGYITAAYITSFSSLI
                     ILLLLIGAIGYSIWRAKKDKTA"
     CDS             complement(8861..9988)
                     /locus_tag="ctg6_61"
                     /transl_table=11
                     /translation="MNKYITYLFLLLLSCGKPQDNNGIFTMDLSKDDLPKTTVSLDDYT
                     TKWTRIDLETTEDCLLDPSFNIYPTDHFIVAYSFNRILVFDHTGHFIREISHFGEGPDE
                     HGLLFNCTVNPTSEQLVFVEMGNTEEIIRYDLSSGKQLTAIPIVAKKQLCDLLFIKDST
                     LVCFPYAGNQKQMAYKQNLAGEWIGTPPIPISEPAGPYNPIPISLFQVDNQWIYKGIYE
                     DTLYLVNNLEPFARFSRKDISPSKTELEVQNSSFINHLFTSNGMSLFGYPQYQLKEVSE
                     GIFDLVLVDFRAFLFNHADKQILEIEKMNCPPLSIIYEQKNLNDLFMLISSRNPKKLVL
                     KVPAEFMGKEEDENPVLFISDLIYPKKKQPTRGKP"
     CDS             complement(10001..11557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_62"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 4.9e-08,
                     bitscore: 25.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.6e-15, bitscore: 49.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.5e-10, bitscore: 31.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.8e-09, bitscore:
                     27.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLEYKNSPVLGFILNSKYYLYDRYSNSIFTVPRIFFEYLDDLI
                     SLDTDEFTQKYHNIFSKEEIIDLFKTLDYCQNDKKLIKPNRIPKFTISSIYSNAKKVEK
                     KLKKELTFLCINITEECNLRCEYCIFSGKYTKSRRHNSNNQIEWNYIEKGVNLFLEHST
                     DSNIRKIGFYGGEPLLYFDIIRKTINYVRSKCDNAIFTITTNATLLKDKILSFFVENNV
                     EITISLDGPQNIHDKNRIFPNGVGSFNTVIKNIESIKRLHHDFFENNIKFSATLSPGKY
                     KIKDLIDFFTYDMFPTLKRADLPLSLNYINYEENKYLSEVKYLDWTKKTENEIFKLYKK
                     IHIKGINKTSEIPAVLRALPIHREMMYINLRSNIAFDEFKFFWPNGACIPGMRSIFLNS
                     KGIFLPCEKLNSETEFCIGDVSTGFDIKKISQLIADYSREIAPLCSNCWAFRFCGECWT
                     TAVKNGQISKDFRSQYCSYIKSYWARRLFLYTEIIEKNPKAFSYQGSIDYPEFMSHMIN
                     E"
     CDS             complement(11601..11774)
                     /locus_tag="ctg6_63"
                     /transl_table=11
                     /translation="MKQKTKKISWENFKDEIKVISAGQQKLLTGGGCACCICSPGNGNS
                     GLGGSTKASISH"
     CDS             complement(11795..12538)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_64"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-11, bitscore:
                     35.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.1e-07, bitscore: 24.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNSFDIVYNNIRKIQLNNTRYFEQYVTINSVYSINITSSLSEFT
                     NYLEAHFKNKFAINIQSSEINDEYTKFHNNFTKSFLSIYENIHIQGFENSSPPLFIISS
                     DLHKKMMFFSRRSNNILQEETRFIPIKSCLPYLNKIYISPTGDIFMCSDLYYIKGFNIG
                     NIDKSIELNKLQDIMTQYTNFRNKTCKKCWVYRFCDFCFYTLYASKERKGINKYCKIIK
                     YDYAQVIKSYIKILKSNGSAFDIYY"
ORIGIN
        1 ctgttttgat ggattttctt tcagaaaatg aagctgtgtt taaaaattca gttcgattga
       61 ttgaacagga gaacaaaggt gtttctgcag cgaggaacca aggtattaaa gaagctagag
      121 gtgagattat tgcctttctt gatgctgatg acgagtggtt acctgattat ttaaaaacta
      181 tcgctttctt ggttgaaaaa tatccggaat gtgatatttt tggtacagct tattcattta
      241 agatgaataa tatgataact cccgcatcaa ttgattatta ttcttttaaa gagaatgagg
      301 gtattttaga taattatttt acgatggcct caaaagcgag aggacctatt tggacttcag
      361 ctgtggctgt tcgaaaaaag gctattttat ctattggttg tttccctgag ggcatttctt
      421 taggtgaaga tgtaatcgtt tgggctaaat tagcttgctt gtataaaata gcttattcga
      481 aatcaaacct agcattgtat agaagagata gcagttgcta tttgagtgtt aagaaaaata
      541 tgcagccagc aataaaagaa gactatgttg gtatagagct ttggaggcta aactgctctt
      601 atcagataaa agacttagat aattatgttt atctttggta caagataaga tttgtaatct
      661 ttgtttttga taatgataag aaaagtgcat ttttggagta tatacgttta ttgccttggg
      721 gattattgaa tttggattgt aactatcatt tgtttttaaa ttgtttacca tattccttgt
      781 tagttaaatt aaatacttgt gttcggagga tatttagaaa aaaagtttga tataatttta
      841 gattatggaa gaaaaccaac ataccgaatt caaagagtca tggcatgacg aatatacccg
      901 ttatatatca gctttctgta atacggaggg tggtgtatta tatatcggta tcgatgataa
      961 aggagaagtt gtagggatag agcagccaaa gaagttgatt gagaaactgc cgaactttat
     1021 cgctcagaaa acgggtatta tgcctcttat ccatttgagg gagaaggccg gtaaagaata
     1081 tttggaaata gaagtccaac cttctgccat gccgatttcc gtgcatggac ggtattatac
     1141 ccggagtgga agcgttactt ccgagctaca agggaatcag ctaaatatgt ttttggctgc
     1201 gaaaatgggt ttgacatggg aaagtgtgat cgaggaggat ttctcattgg aggacataga
     1261 taccgatacg gtagaacgtt ttaagctatt ggctaaagac cgggttcctt ccatcgagca
     1321 ggaaacggat ctgctggctt tgatggagcg gttgaatttg atcgtaggag gccgtttcaa
     1381 gagagccgct gtagtcttgt ttggaaagaa tgtgcagaga tatgtgttac aagctcgtat
     1441 taaaatagga aagttcctta ccgatacgga ggtactgaca accgatattg tcgaggggaa
     1501 cctgattcag caggttgatc gggctttgga tatattgcga acgaaatatt tattaagtta
     1561 tatatcgtat gaggggattc ataggcgtga gaaactggtt tatccctacg aggctctgcg
     1621 ggaagcctta ttgaattcga ttatccatcg agaatatttt gtttcttccg aaattcaggt
     1681 acgtgtttac gaggacaagc tggtgatagg gaatgaagct cgtttgcacg atattacggt
     1741 tgaggacttg tctcgtcctc acccctctag acctcataat aagttgatag cggatgtttt
     1801 ttacaaagct ggctttatcg agagttgggg acggggaaca caacgtatta ttgacaactg
     1861 cttggcagaa ggattatccg ctcctgtata tgagcataag atgggttttt tatacttgac
     1921 tttttttcat gagcggataa atgagcggat aaatgagcgg ataaatgagc ggataaatga
     1981 attgtcggat atggaacggg aggtatatca gatcttgcga gaggagccta ctatccgtca
     2041 aatagattta gcaaatcgtt tggatttgac agagcagtat atccggaagc ttataaaaaa
     2101 gttgaaagag catggttgga ttgaacgcat tggagctagg aaaaatggtt attggaaaat
     2161 aatagagaag tcatgaagat attgatatta aatacctctg aattaaccgg tggagcggca
     2221 gtcgccgcaa accgactagc gaaagcattg ggtaaatctg gtgtagaggt ttctatgtta
     2281 gtacgtgatc ggaaaacaga ccatgtaaaa gttttctctg taaataattc atggacttca
     2341 cataggctta attcttttcg cttcatttgg gaacgactga taatctttat ctgtaacttc
     2401 tttagcaaga agaacctctt tcaagtttcc atagccaata caggcacgga tttatcgaag
     2461 cacccattag tgcaacaggc ggatgtgatt catctgcatt gggtgaatca aggatttttg
     2521 tctctttctg atattaagaa attagtaaat accggaaaac ctattgtgtg gactatgcat
     2581 gatttgtggc cagctacggc tatttgtcat tatccgggag gatgtgagaa gtatatatcg
     2641 aattgttatc agtgcccgat gctgaaacga aatccgtttt ttgatttagc ggcttctgtt
     2701 tttaaggaga aagggaaaat agggttatct aagattacat ttgtcggttg tagccgatgg
     2761 ataatggaag aggcccaaaa aggcaattgg ttgagaacag cctgttttac ctcgattcct
     2821 aacccgattg acgtgacagc ctttaagcgt atggaaaagc gggtggcccg taaacgattc
     2881 gacctgccgg aaggtaagtt ccttcttctt tttgccgccg ctaagctttc agatacccgg
     2941 aaaggagcga tttttttgat cgaggcttgc gaaaaactaa aagagaaata ccaagatcgc
     3001 atagaaatcg tgttgatggg aaatagctcg gaagaattga ttagccagtt tccttttaag
     3061 gtgaatacgc tgggatatat atcggatcaa gactctatga tttccgttta tgcctgtgcc
     3121 gatatgttcg ttattccttc gttggaggat aacttaccca atacgattat ggagtcgatg
     3181 gcatgcggta cgccttgtgt gggatttgag acaggaggga ttccggagat gatagatcat
     3241 ttgaagaatg ggtatgtagc taaatataag gatacaaatg atttggctgt agggattaag
     3301 tggataattg acaaccaaga gacttttcga tttagtgagg cttgcgtccg caaggtgcat
     3361 gattgctata gggaatcggt tattgccgaa aaatatatag ctttgtatca gagcctgtgt
     3421 aataagagaa aatagcgtga aagaagatca gcatatcgaa gtaagaatga atgcttgctg
     3481 gtaagtgatt gaaagcaaat gaaaattgct acatttgtgg aaaaatggaa taaatggacg
     3541 atcagcataa gcctgaatgg attaaggtgg acgagtggga ttttgtagaa tatgtggata
     3601 gcttgttgcg tagtcaagag gctgtcgatt tagagtttaa gaccgctcgt gccggattcc
     3661 caaatagtgt gtgggaaacg tattcttcat ttgcgaatac agatggagga actatcgttc
     3721 tgggaataaa ggagaaaaat ggggcactat ttgtggaggg acttcttcca gagcaaattg
     3781 tgtcttatcg gcaaatcatt tgtaaccaat tgaataatcc ggattgcgtt aatgttaatt
     3841 tacttactga caagaatatt caagaggtag actatagagg aaaatctctt ttgctgattt
     3901 atgttccgag agcatctcgt tcacaacgtc ctgtatattt aacaagaaat cccttgaatg
     3961 gacatactta taaacgaaat aatgagggag attataaatg tacggatacg gaagttcgca
     4021 gaatgattgc cgatgcggat gaggaacatc cgagagattc tcgtatttta tgtaattatt
     4081 caatggaaga tattgatttg gactcactta aacaatatcg actgctactt tctagtcgtc
     4141 agccagatca cccttggttg acacttgatg atatggcttt tttgagaaaa ttgggaggat
     4201 atcgacaaga taggcaaaca ggtcaagaag ggtttacttt agcgggtata ttaatgtttg
     4261 gaaggacaga aagtataacg gataatgaat gtgctccatc ttattttccg gattatcagg
     4321 aaaaaatgtc ggtagatgag aatgttagat ggacagatcg catttgtatg gatggaactt
     4381 gggaagcgaa tctttttcaa ttttatcggc gtgtgtatcc taaattatca tctgtactgc
     4441 ctaagccatt ccgtttggag aatggtgtga gattggaaga tactaccacg catgtcgctt
     4501 tacgtgaggc atttgtaaat acattggtgc attgtgatta tatggaggaa ggaaatataa
     4561 cgatagaaca atggaaagat cgttatgtat ttaaaaatcc cggaacactg ctagtgagta
     4621 aggcccagta ttatgccgga ggtgaaagta tatgccgtaa taagagcttg caaaagatgt
     4681 ttatgctgat tggcttctct gagaaagcag gaagtggggt gaataagatt tttatgggtt
     4741 ggaaaaatgc gaattggaga cctccatttg tggaggagca aagtcacccg gatcgggtgg
     4801 tgttgaattt accgatggaa agtttgtatc cagaggaagt cttagaagaa cttaagcgtc
     4861 tgtttggacg ggaaattgaa agaattccat atgatcaatt cacggttttg gctctttgtt
     4921 actctgaaaa acaagtatct aatgaaagac ttcaatatat tttgaaccaa catagctcaa
     4981 atattacaaa gctactaaaa agtatgtgca atgctggttt tttggagtct ataggaaatg
     5041 gccggggaac taggtaccgt ttgctgtttt tggagaagga tgaaagcaag cctcaaaagg
     5101 atgaaagcaa actgaagaag gatgaaagca agtctcaaaa agatgaaagc aaactggaga
     5161 aggatgaaag taagaaatat atgcgttatg aggatttgtc gaggttaata ctatctgttt
     5221 gtgaggatta tgtagctctg gaaataatag cggaagctgt tcatagagag gcttcttatt
     5281 taattaatcg ggttatacca agaatgttag aggatgggct actagagaga ttatatccgt
     5341 cttctcctaa gcatccttta caaaaatatc gtgtgagaca agtcggaaat ttataagaga
     5401 taatggaaat gaatcagcaa cctacatttt cgatcataac gatcacctat aatgcggagc
     5461 gatggttgga gcgtacgata ttgagcgtac ttagccagtc gtatccgaat atcgagtata
     5521 tattgattga cggagcgtcg aaggataaga ccgtagagat catcaagcaa tatgagtccg
     5581 gtatcgcttc ttggataagc gagcctgata aaggcttgta tgatgctatg aataagggat
     5641 tgaagcgggc tacgggggat tatgtgtggt tcctgaatgc gggggataca ctttataccg
     5701 cagataccgt gcaaagaatt gtggcgtctt tgaaaaagaa agtatctttg ccagacgtga
     5761 tttacggaga gacccagatc gttgatgcgg agggtagatc attagggatg cgcagattga
     5821 aagcaccgga gaaactgact tggaaaagtt tccggatggg aatgttggtt tgtcaccagt
     5881 cgtttatatc aaaacgggag atcgctccgt tatataatac ggaataccgt ttgacggcgg
     5941 attatgattg gtgtatccaa tgtctgagac gatcgaaaag aatacataat acacgtttga
     6001 ccctgtctaa ttttttagag gaaggattaa gtagtgtgaa ccggaaagct tccttaaagg
     6061 agcgatatga ggtcatgtgt aagtattatg gcaaggtgtc gacgattctg ttgcatggtt
     6121 ggttcgccgt gagattctat tttgccaaat ggtttaaagg tagagtataa acaataaatt
     6181 atagataagt tttatgcgga gtataatgag taaatgggga aaacatatcg cagcgatagc
     6241 cgtattcttg gtattgacgg tgatttattt ttctccggcc gtatttgagg gtaaggtagt
     6301 ccggcaaggg gatacggaaa aggctatcgg tatggggaat agccagatgg atgaatatga
     6361 gaagacggcc caaccgggag aattcagcgc atggtctgat gctatgtttg gcggaatgcc
     6421 ttatgtgtcg ggatatggaa atccggctcc acgatttccc ggatatcttt tagtggagaa
     6481 gcctttaaaa gcgctggggt atatggatgc ggggatggtg tttaccggat tcgtttgttt
     6541 ctatatcttg atgtgtgtca tgggcgtaaa ttggtggttg gcgatcgctg gtgctatcgc
     6601 tttcgcttta gcatcttata atctgatcat tatagaggcc ggccatgtca cgaaagcgta
     6661 tgtaatcgct tatatgccat taacgttggc gggtatggcc ctgttgttca agcgtaagta
     6721 tttatggggg gcggtcgtgt tcttgttggg tgtcgcattc tctatcgcga atacgcacct
     6781 gcaaatcact tattatttat tattactttg cttcttcgtt tatttgggat atttgttcaa
     6841 taaactgaag gaaaaagctt ataaagaact gggtacggta accgctatta tggctggatg
     6901 cgtgatattg gcggtgttgc cgaatgccca gaatatgtat gctcaatggg atttgggaca
     6961 gaactctatc cgtggggcta cggaattaac gacaacgacc ccttcgggcg agaagatttc
     7021 ttccggctta gacaaggatt atgcgttcgc ttggagctat ggaaaagggg agttgttgac
     7081 cttgttggtc ccgaatgcct atggtggaag ttcaggtgga atgctaggcc cggattctga
     7141 gctatataag gaattaaggg cgaaaggcgc tcaagtcgga aaagaggtac aggctcctac
     7201 ctattgggga gagaagacat ttacttccgg gccggtttat ttcggggcat tggtctgctt
     7261 cttgtttgtt ctgggaatgt tcgtgatccg gaatccgatg aaatggtggt tattcggagg
     7321 ttctgtcttt ttgatattgc tggcattggg acgtaatttt gatagcttca atgactttat
     7381 gttccattac ttgccgatgt ataataagtt ccgtaccgta gagatggcat tggttattcc
     7441 gggtatggta tttcctatta tcgctatatg gggattgaaa gaggtgttat ccgagaccgt
     7501 gagcgatgcc ttgttgaaga aaggattgat cgctgctttg gctatcacgg ggggcatttc
     7561 tttaatcctt tggttgatgc cgagtatgct gttggatttc cgttcttctt tcgacgctca
     7621 atatcagttg ccagattggt attacaacgc cttgttaatg gatcgtgctt ccttggcttc
     7681 ggcggatgcg ttgcgctctt tggtctttat cttattaggg gcggctttgt tgttctggtt
     7741 ctatacctcg aaagatcgga aaaaggtggc gacattcgta gggatcggtg ttgcggtctt
     7801 gatgttggtt gacttatgga cggtggataa acggtatttg aacgatagta actttatccg
     7861 ccagaaacct acagaggtat ataaagagac ggtagccgat caagaaatca tgaaggataa
     7921 ggacctttct tatcgtgtct tgaatttgaa taatcctttc ttggagacaa cgacctcgta
     7981 ctatcaccat tccgttggtg gttattatgc cgcgaagctg agacggtacc aagaactgat
     8041 cgaccaccgt ctgcaaggag agcttaactc ggttatcgag gctttccaga aagcgcagat
     8101 cgcggaggat ttgatggggg cgttcgctgc ttgcccgtcc ttgaatatgc taaatacacg
     8161 ttatattatc tataatccgg agcaaccgcc tttgaggaat ccgttcgctt tcggcaacgc
     8221 ttggtttgtg gataaagtgg aggtcgtgga gaatgcggat gcggaaatag cggcgttgaa
     8281 tacgattaat ccgttaacga cggcggttgt cgataaacgt ttcgctgatg aggtgaaagg
     8341 tttcacgcct caattggact ctaccgctac gataacattg gatagttatc gccctaataa
     8401 gttagtttat acgacgaaga ctaattctga gcaattagca gtattctctg agatctatta
     8461 tcaaccggga tgggaggcta cgattgatgg gaagcccgct cctcatttcc gggcggattg
     8521 gatattaagg gctatgttag ttcctgcggg agagcatcag atcgtatttg agtttagacc
     8581 gcaaggttat attacggcgg cttatataac ctcatttagt tcattgataa tccttttgtt
     8641 attgattgga gcgatcggtt actcgatctg gagagctaaa aaagacaaga cagcctaaat
     8701 atccagttgt agagacgggg cgtgccccgt ctcggcacag actaatgggt attttaaagt
     8761 ttccattttg aggagatgag acggggcacg ccccgtctct acaactaggt ggaaattggt
     8821 aacgattatt cgttatggat aaagccaagc agttttctcg ttagggtttc ccacgagtgg
     8881 gctgcttttt ctttggatat atcaagtcgg atatgaataa gactgggttt tcatcttctt
     8941 cttttcccat gaattccgct ggaactttta gtaccaattt cttcgggttc cgggaggaga
     9001 tcagcatgaa tagatcattt aaattttttt gttcataaat aattgacaga ggtgggcagt
     9061 tcattttttc tatttcaaga atttgtttgt ctgcgtgatt aaaaaggaag gctcgaaaat
     9121 caactaaaac taaatcgaat atgccttcag atacttcttt taactgatat tgcgggtatc
     9181 cgaataatga cattccgtta gaggtaaaca gatgatttat aaaagagctg ttctgtacct
     9241 ctaattctgt ttttgatgga ctgatgtctt tccttgaaaa acgagcgaaa ggttctaaat
     9301 tattcactaa gtaaagcgtg tcttcgtaga tccctttata gatccattga ttatccactt
     9361 gaaatagact gataggtatg ggattatatg gacctgccgg ttcggagatg ggaatggggg
     9421 gtgttccaat ccattccccg gctagatttt gtttgtaggc catttgcttt tgattgcctg
     9481 cgtatgggaa gcagacaagt gtagagtcct tgataaataa taagtcacat aactgctttt
     9541 ttgcgacgat tggtatcgca gtcaattgtt tgccactcga tagatcataa cgaattattt
     9601 cttcggtatt tcccatttct acgaagacaa gttgttcact cgtaggattg actgtacagt
     9661 tgaataaaag accatgttcg tcgggacctt ctccgaaatg ggagatctcg cggataaaat
     9721 gtcctgtatg gtcgaatacg aggattcgat taaaggaata agcgacaata aaatgatctg
     9781 tagggtagat gttaaacgat ggatcaagta ggcaatcttc agtagtctca agatctatcc
     9841 ttgtccattt ggttgtataa tcatccaatg ataccgttgt tttgggaagg tcatctttgg
     9901 atagatccat tgtgaatata ccgttattat cttggggctt tccgcaagat aataataaaa
     9961 ggaatagata tgtaatgtat ttgttcatgg ttgttttagt ttattcgtta atcatgtgag
    10021 acataaattc aggataatct atacttcctt gataagagaa tgctttggga tttttttcga
    10081 ttatttctgt atacaaaaat agccttcttg cccaataact ttttatataa ctgcaatatt
    10141 gcgatctaaa atcttttgat atttgtccat tctttactgc ggttgtccag cattccccac
    10201 aaaacctaaa tgcccagcag ttggaacata gtggagctat ttctcttgag taatctgcta
    10261 tgagttgtga tatttttttt atgtcaaatc ctgttgatac atcacctatg caaaactctg
    10321 tttctgaatt tagtttctcg catggcaaaa agatcccttt agaattcaag aaaatacttc
    10381 tcatcccagg tatgcaggct ccattaggcc aaaagaactt aaattcatca aaagctatat
    10441 tacttcttaa attgatatac atcatttctc gatgaatagg tagggctctt agaactgctg
    10501 gtatttcaga agttttattg attcctttta tatggatttt tttatataac ttaaaaattt
    10561 cgttttcagt tttttttgtc caatctaaat attttacttc gcttaaatat ttattttctt
    10621 cgtaatttat ataattaaga cttaatggaa ggtctgctct tttcagcgta gggaacatat
    10681 cgtatgtaaa aaagtcaatt aaatctttga ttttgtattt cccaggtgat aatgtcgctg
    10741 agaattttat attattttca aaaaaatcat gatgtaatcg tttgatagat tctatgtttt
    10801 ttatgacggt gttaaaactc ccaacgccat taggaaaaat cctgttttta tcatgaatgt
    10861 tttgaggacc atctaggcta atggtgatct ctacattatt ttctacaaag aaagacaaaa
    10921 ttttgtcttt tagtaaagtt gcatttgtgg taattgtgaa aattgcgtta tcacatttac
    10981 ttcggacata attgatagtt tttcttatta tgtcaaaata tagaagaggt tctcctccat
    11041 agaaacctat ttttctaata ttagagtctg tgctgtgttc taagaataaa ttaacacctt
    11101 tttctatata attccactcg atttgattgt tgctgttatg tcttcttgat ttcgtatatt
    11161 tcccagagaa tatgcagtac tcgcatctga gattacattc ttcagttata tttatgcata
    11221 ggaaggttaa ttcttttttg agtttctttt ctactttttt agcgttagaa tagatggatg
    11281 aaatggtgaa tttaggtatt ctattaggtt ttattagttt tttgtcgttt tggcaataat
    11341 ctaatgtctt aaatagatct ataatctcct cttttgaaaa aatattatga tatttttgag
    11401 tgaattcatc tgtgtcaagg ctaattagat cgtctaaata ctcaaaaaat attcttggaa
    11461 ctgtaaaaat ggaattggaa tatctatcgt ataggtaata ttttgaattt aaaatgaaac
    11521 ctagtactgg gctatttttg tattctagtt tttccataaa gtgaaagctt atgcggggag
    11581 agaaatctcc ccgcaggtta ttaatgtgaa attgaagctt tggttgagcc tcctaaaccg
    11641 ctattcccat tacctgggct acagatgcag caagcacatc cacctccggt gagtaacttt
    11701 tgctgtccgg cagagattac tttaatctcg tctttaaagt tttcccatga gattttcttc
    11761 gttttttgtt tcatacgctg aataatttta tatgttagta atatatatca aacgcactcc
    11821 cgtttgattt taatatctta atatatgatt tgatgacttg ggcgtaatca tattttatta
    11881 ttttacaata tttatttatt ccttttcgtt ctttagaagc atataatgta taaaaacaaa
    11941 aatcgcagaa tctataaacc caacattttt tacatgtttt atttctgaag ttagtgtatt
    12001 gtgtcattat atcttgtagc ttgtttaatt ctatagattt atcaatattt ccgatattaa
    12061 atccttttat gtaatataaa tcgctgcaca tgaaaatgtc acctgtcggt gatatatata
    12121 tcttgtttaa gtaaggaagg cagcttttta tgggaataaa tcttgtttct tcttgcagga
    12181 tgttgtttga tcttcttgaa aagaacatca tctttttatg taagtcgctg gaaattataa
    12241 ataaaggggg ggagctattt tcgaatcctt gtatgtgtat attttcatat attgataaaa
    12301 aggattttgt gaaattatta tggaatttcg tgtattcatc gtttatctca gatgattgaa
    12361 tatttatagc aaatttattt ttgaaatgtg cttctagata gttggtgaat tcggaaaggg
    12421 aacttgttat attgattgaa tatacggaat ttattgttac atattgttcg aagtatcttg
    12481 tgttgtttag ttgtattttg cgtatattgt tatatactat atcaaaactg ttttttttat
//
